Page last updated: 2024-09-03

n,n-dipropyl-2-(4-methoxy-3-(2-phenylethoxy)phenyl)ethylamine monohydrochloride and fluvoxamine

n,n-dipropyl-2-(4-methoxy-3-(2-phenylethoxy)phenyl)ethylamine monohydrochloride has been researched along with fluvoxamine in 6 studies

Compound Research Comparison

Studies
(n,n-dipropyl-2-(4-methoxy-3-(2-phenylethoxy)phenyl)ethylamine monohydrochloride)
Trials
(n,n-dipropyl-2-(4-methoxy-3-(2-phenylethoxy)phenyl)ethylamine monohydrochloride)
Recent Studies (post-2010)
(n,n-dipropyl-2-(4-methoxy-3-(2-phenylethoxy)phenyl)ethylamine monohydrochloride)
Studies
(fluvoxamine)
Trials
(fluvoxamine)
Recent Studies (post-2010) (fluvoxamine)
980292,051518434

Protein Interaction Comparison

ProteinTaxonomyn,n-dipropyl-2-(4-methoxy-3-(2-phenylethoxy)phenyl)ethylamine monohydrochloride (IC50)fluvoxamine (IC50)
DRattus norvegicus (Norway rat)0.54
D(3) dopamine receptorRattus norvegicus (Norway rat)0.54
D(1B) dopamine receptorRattus norvegicus (Norway rat)0.54
D(4) dopamine receptorRattus norvegicus (Norway rat)0.54
Sodium-dependent serotonin transporterHomo sapiens (human)0.0038
Sodium-dependent serotonin transporterRattus norvegicus (Norway rat)0.54
D(2) dopamine receptorRattus norvegicus (Norway rat)0.54
Potassium voltage-gated channel subfamily H member 2Homo sapiens (human)3.1
TransporterRattus norvegicus (Norway rat)0.54

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (16.67)29.6817
2010's5 (83.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fujita, Y; Hashimoto, K; Iyo, M1
Bhuiyan, MS; Fukunaga, K; Shioda, N; Tagashira, H1
Bhuiyan, MS; Fukunaga, K; Tagashira, H1
Kanazawa, M; Kubota, H; Mori, T; Rahmadi, M; Shibasaki, M; Suzuki, T1
Balogh, D; Fekete, A; Hodrea, J; Hosszu, A; Koszegi, S; Lenart, L; Szabo, AJ; Szkibinszkij, E; Vannay, A; Veres-Szekely, A; Wagner, L; Zelena, D1
Kamei, C; Karube, Y; Matsushima, Y; Sugimoto, Y; Takata, J; Terada, K1

Other Studies

6 other study(ies) available for n,n-dipropyl-2-(4-methoxy-3-(2-phenylethoxy)phenyl)ethylamine monohydrochloride and fluvoxamine

ArticleYear
Phencyclidine-induced cognitive deficits in mice are improved by subsequent subchronic administration of fluvoxamine: role of sigma-1 receptors.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2007, Volume: 32, Issue:3

    Topics: Analysis of Variance; Animals; Anisoles; Antipsychotic Agents; Behavior, Animal; Choice Behavior; Cognition Disorders; Dehydroepiandrosterone Sulfate; Drug Administration Schedule; Drug Interactions; Exploratory Behavior; Fluvoxamine; Mice; Mice, Inbred ICR; Motor Activity; Nootropic Agents; Phencyclidine; Piperazines; Propylamines; Receptors, sigma; Retention, Psychology; Selective Serotonin Reuptake Inhibitors; Sigma-1 Receptor

2007
Targeting sigma-1 receptor with fluvoxamine ameliorates pressure-overload-induced hypertrophy and dysfunctions.
    Expert opinion on therapeutic targets, 2010, Volume: 14, Issue:10

    Topics: Animals; Anisoles; Blood Pressure; Cardiotonic Agents; Female; Fluvoxamine; Heart; Humans; Hypertrophy, Left Ventricular; Myocardium; Ovariectomy; Propylamines; Rats; Rats, Wistar; Receptors, Glycine; Receptors, sigma; Selective Serotonin Reuptake Inhibitors; Sigma-1 Receptor; Signal Transduction; Up-Regulation

2010
Sigma-1 receptor stimulation with fluvoxamine activates Akt-eNOS signaling in the thoracic aorta of ovariectomized rats with abdominal aortic banding.
    European journal of pharmacology, 2011, Jan-15, Volume: 650, Issue:2-3

    Topics: Animals; Anisoles; Aorta, Abdominal; Aorta, Thoracic; Aortic Valve Stenosis; Cardiomegaly; Dose-Response Relationship, Drug; Female; Fluvoxamine; Nitric Oxide Synthase Type III; Ovariectomy; Phosphorylation; Propylamines; Proto-Oncogene Proteins c-akt; Rats; Rats, Wistar; Receptors, sigma; Selective Serotonin Reuptake Inhibitors; Sigma-1 Receptor; Signal Transduction

2011
Involvement of sigma 1 receptor in the SSRI-induced suppression of the methamphetamine-induced behavioral sensitization and rewarding effects in mice.
    Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology, 2013, Volume: 33, Issue:2

    Topics: Animals; Anisoles; Behavior, Animal; Disease Models, Animal; Fluvoxamine; Methamphetamine; Mice; Propylamines; Rats; Receptors, sigma; Reward; Schizophrenia; Selective Serotonin Reuptake Inhibitors; Sigma-1 Receptor

2013
The role of sigma-1 receptor and brain-derived neurotrophic factor in the development of diabetes and comorbid depression in streptozotocin-induced diabetic rats.
    Psychopharmacology, 2016, Volume: 233, Issue:7

    Topics: Animals; Anisoles; Brain; Brain-Derived Neurotrophic Factor; Depression; Depressive Disorder; Diabetes Mellitus, Experimental; Fluvoxamine; Male; Narcotic Antagonists; Propylamines; Rats; Receptors, sigma; Selective Serotonin Reuptake Inhibitors; Sigma-1 Receptor; Signal Transduction

2016
Effects of fluvoxamine on nerve growth factor-induced neurite outgrowth inhibition by dexamethasone in PC12 cells.
    Bioscience, biotechnology, and biochemistry, 2019, Volume: 83, Issue:4

    Topics: Animals; Anisoles; Anti-Anxiety Agents; Cell Differentiation; Dexamethasone; Fluvoxamine; Gene Expression Regulation; Glucocorticoids; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Morpholines; Nerve Growth Factor; Neuronal Outgrowth; Neurons; PC12 Cells; Phosphorylation; Propylamines; Proto-Oncogene Proteins c-akt; Rats; Receptors, sigma; Sigma-1 Receptor; Signal Transduction

2019