Page last updated: 2024-09-03

n,n-dipropyl-2-(4-methoxy-3-(2-phenylethoxy)phenyl)ethylamine monohydrochloride and dextromethorphan

n,n-dipropyl-2-(4-methoxy-3-(2-phenylethoxy)phenyl)ethylamine monohydrochloride has been researched along with dextromethorphan in 3 studies

Compound Research Comparison

Studies
(n,n-dipropyl-2-(4-methoxy-3-(2-phenylethoxy)phenyl)ethylamine monohydrochloride)
Trials
(n,n-dipropyl-2-(4-methoxy-3-(2-phenylethoxy)phenyl)ethylamine monohydrochloride)
Recent Studies (post-2010)
(n,n-dipropyl-2-(4-methoxy-3-(2-phenylethoxy)phenyl)ethylamine monohydrochloride)
Studies
(dextromethorphan)
Trials
(dextromethorphan)
Recent Studies (post-2010) (dextromethorphan)
980292,020342593

Protein Interaction Comparison

ProteinTaxonomyn,n-dipropyl-2-(4-methoxy-3-(2-phenylethoxy)phenyl)ethylamine monohydrochloride (IC50)dextromethorphan (IC50)
Sodium channel protein type 1 subunit alphaRattus norvegicus (Norway rat)1.3
Sodium channel protein type 2 subunit alphaRattus norvegicus (Norway rat)1.3
Sodium channel protein type 3 subunit alphaRattus norvegicus (Norway rat)1.3
Cytochrome P450 2D26Rattus norvegicus (Norway rat)5.6
Cytochrome P450 2D6Homo sapiens (human)2.1768
Sodium-dependent serotonin transporterHomo sapiens (human)0.0027
Sigma non-opioid intracellular receptor 1Cavia porcellus (domestic guinea pig)0.1236

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (66.67)18.2507
2000's1 (33.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hashimoto, K; Iyo, M; Minabe, Y; Narita, N; Yamazaki, K1
Chaki, S; Muramatsu, M; Nakazato, A; Ogawa, S; Okuyama, S; Tanaka, M; Tomisawa, K1
Baeyens, JM; Cobos, EJ; Del Pozo, E1

Other Studies

3 other study(ies) available for n,n-dipropyl-2-(4-methoxy-3-(2-phenylethoxy)phenyl)ethylamine monohydrochloride and dextromethorphan

ArticleYear
Lack of neuroprotective effect of sigma receptor ligands in the neurotoxicity of p-chloroamphetamine in rat brain.
    European journal of pharmacology, 1995, Oct-06, Volume: 293, Issue:3

    Topics: Animals; Anisoles; Antitussive Agents; Cerebral Cortex; Dextromethorphan; Haloperidol; Hydroxyindoleacetic Acid; Ligands; Male; p-Chloroamphetamine; Propylamines; Rats; Rats, Sprague-Dawley; Receptors, sigma; Serotonin; Serotonin Agents

1995
Solubilization and characterization of binding sites for [3H]NE-100, a novel and potent sigma 1 ligand, from guinea pig brain.
    Life sciences, 1996, Volume: 59, Issue:16

    Topics: Animals; Anisoles; Binding, Competitive; Brain; Dextromethorphan; Guinea Pigs; Ligands; Male; Pentazocine; Phenytoin; Propylamines; Radioligand Assay; Receptors, sigma; Tritium

1996
Phenytoin differentially modulates the affinity of agonist and antagonist ligands for sigma 1 receptors of guinea pig brain.
    Synapse (New York, N.Y.), 2005, Mar-01, Volume: 55, Issue:3

    Topics: Allosteric Regulation; Animals; Anisoles; Anticonvulsants; Binding, Competitive; Brain; Dextromethorphan; Drug Interactions; Ethylenediamines; Guinea Pigs; Haloperidol; Ligands; Male; Morpholines; Neurons; Phenazocine; Phenytoin; Piperazines; Piperidines; Progesterone; Propylamines; Receptors, sigma; Synaptic Transmission

2005