n,n-dipropyl-2-(4-methoxy-3-(2-phenylethoxy)phenyl)ethylamine monohydrochloride has been researched along with alpha-(4-fluorophenyl)-4-(5-fluoro-2-pyrimidinyl)-1-piperazine butanol in 4 studies
| Studies (n,n-dipropyl-2-(4-methoxy-3-(2-phenylethoxy)phenyl)ethylamine monohydrochloride) | Trials (n,n-dipropyl-2-(4-methoxy-3-(2-phenylethoxy)phenyl)ethylamine monohydrochloride) | Recent Studies (post-2010) (n,n-dipropyl-2-(4-methoxy-3-(2-phenylethoxy)phenyl)ethylamine monohydrochloride) | Studies (alpha-(4-fluorophenyl)-4-(5-fluoro-2-pyrimidinyl)-1-piperazine butanol) | Trials (alpha-(4-fluorophenyl)-4-(5-fluoro-2-pyrimidinyl)-1-piperazine butanol) | Recent Studies (post-2010) (alpha-(4-fluorophenyl)-4-(5-fluoro-2-pyrimidinyl)-1-piperazine butanol) |
|---|---|---|---|---|---|
| 5 | 0 | 2 | 90 | 1 | 2 |
| 98 | 0 | 29 | 90 | 1 | 2 |
| Protein | Taxonomy | n,n-dipropyl-2-(4-methoxy-3-(2-phenylethoxy)phenyl)ethylamine monohydrochloride (IC50) | alpha-(4-fluorophenyl)-4-(5-fluoro-2-pyrimidinyl)-1-piperazine butanol (IC50) |
|---|---|---|---|
| Cytochrome P450 3A4 | Homo sapiens (human) | 0.83 | |
| Tryptophan 5-hydroxylase 1 | Rattus norvegicus (Norway rat) | 6.43 | |
| 5-hydroxytryptamine receptor 2A | Rattus norvegicus (Norway rat) | 0.83 | |
| Alpha-1B adrenergic receptor | Rattus norvegicus (Norway rat) | 0.8267 | |
| 5-hydroxytryptamine receptor 1A | Rattus norvegicus (Norway rat) | 0.91 | |
| Alpha-1D adrenergic receptor | Rattus norvegicus (Norway rat) | 0.8267 | |
| 5-hydroxytryptamine receptor 1B | Rattus norvegicus (Norway rat) | 1.5 | |
| 5-hydroxytryptamine receptor 1D | Rattus norvegicus (Norway rat) | 1.5 | |
| 5-hydroxytryptamine receptor 1F | Rattus norvegicus (Norway rat) | 1.5 | |
| Alpha-1A adrenergic receptor | Rattus norvegicus (Norway rat) | 0.8267 | |
| D(2) dopamine receptor | Mus musculus (house mouse) | 2.431 | |
| D(2) dopamine receptor | Rattus norvegicus (Norway rat) | 6.9225 | |
| Sigma non-opioid intracellular receptor 1 | Homo sapiens (human) | 0.06 | |
| Sigma non-opioid intracellular receptor 1 | Rattus norvegicus (Norway rat) | 0.073 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chaki, S; Hatayama, K; Kawashima, Y; Nakazato, A; Ohta, K; Okuyama, S; Sekiguchi, Y | 1 |
| Araki, H; Ogawa, S; Okuyama, S; Otomo, S; Tsuchida, K | 1 |
| Araki, H; Ogawa, S; Okuyama, S; Otomo, S | 1 |
| Furukawa, H; Hasegawa, T; Kitaichi, K; Nabeshima, T; Noda, Y | 1 |
4 other study(ies) available for n,n-dipropyl-2-(4-methoxy-3-(2-phenylethoxy)phenyl)ethylamine monohydrochloride and alpha-(4-fluorophenyl)-4-(5-fluoro-2-pyrimidinyl)-1-piperazine butanol
| Article | Year |
|---|---|
Design, synthesis, structure-activity relationships, and biological characterization of novel arylalkoxyphenylalkylamine sigma ligands as potential antipsychotic drugs.
Topics: Animals; Anisoles; Antipsychotic Agents; Brain; Drug Design; Drug Evaluation, Preclinical; In Vitro Techniques; Ligands; Male; Mice; Mice, Inbred ICR; Propylamines; Radioligand Assay; Rats; Rats, Wistar; Receptors, Dopamine D2; Receptors, sigma; Stereotyped Behavior; Structure-Activity Relationship | 1999 |
The sigma-selective ligand NE-100 attenuates the effect of phencyclidine in a rat diving model.
Topics: Animals; Anisoles; Carbazoles; Diving; Male; Motor Activity; Phencyclidine; Piperidines; Propylamines; Pyrimidines; Rats; Rats, Wistar; Receptors, sigma | 1995 |
Effect of NE-100, a novel sigma receptor ligand, on phencyclidine-induced cognitive dysfunction.
Topics: Animals; Anisoles; Anti-Anxiety Agents; Cognition Disorders; Drug Interactions; Ligands; Male; Phencyclidine; Physical Exertion; Piperidines; Propylamines; Pyrimidines; Rats; Rats, Wistar; Receptors, sigma; Ritanserin; Swimming | 1994 |
In vivo functional interaction between phencyclidine binding sites and sigma receptors to produce head-weaving behavior in rats.
Topics: Animals; Anisoles; Behavior, Animal; Binding Sites; Dizocilpine Maleate; Guanidines; Male; Phenazocine; Piperidines; Propylamines; Pyrimidines; Rats; Rats, Wistar; Receptors, Phencyclidine; Receptors, sigma | 1996 |