Page last updated: 2024-09-03

n,n-dimethylarginine and symmetric dimethylarginine

n,n-dimethylarginine has been researched along with symmetric dimethylarginine in 229 studies

Compound Research Comparison

Studies
(n,n-dimethylarginine)
Trials
(n,n-dimethylarginine)
Recent Studies (post-2010)
(n,n-dimethylarginine)
Studies
(symmetric dimethylarginine)
Trials
(symmetric dimethylarginine)
Recent Studies (post-2010) (symmetric dimethylarginine)
2,2162281,22142827314

Research

Studies (229)

TimeframeStudies, this research(%)All Research%
pre-19901 (0.44)18.7374
1990's2 (0.87)18.2507
2000's57 (24.89)29.6817
2010's146 (63.76)24.3611
2020's23 (10.04)2.80

Authors

AuthorsStudies
Nissim, I; Pereira, G; Segal, S; Yudkoff, M1
Kim, S; Lee, YJ; Paik, WK; Park, JO; Rawal, N; Whitaker, JN1
Dillon, MJ; Frend, A; Goonasekera, CD; Rees, DD; Shah, V; Woolard, P1
Fleck, C; Janz, A; Karge, E; Schweitzer, F; Schwertfeger, M; Stein, G1
Beck, W; Deppisch, RM; Pommer, W; Riedel, E; Schröder, M1
Bode-Böger, SM; Böger, RH; Chowienczyk, PJ; Fisher, I; Jackson, G; McGing, E; Ritter, JM; Walker, HA1
Balint, RF; Cooke, JP; Her, JH; Kimoto, M; Stühlinger, MC; Tsao, PS1
Aso, T; Azuma, H; Beppu, M; Goto, M; Obayashi, S1
Deng, HW; Jiang, JL; Li Ns, NS; Li, YJ1
Adimoolam, S; Asagami, T; Cooke, JP; Ito, A; Kimoto, M; Lin, KY; Reaven, GM; Tsao, PS; Tsuji, H1
Bonfigli, AR; Coppa, G; Gambini, A; Marra, M; Testa, I; Testa, R1
Brattström, L; Brudin, L; Hultberg, B; Teerlink, T; Wanby, P1
Dweik, RA1
Gehring, H; Pahlich, S; Zakaryan, RP1
Blomster, H; Kontkanen, M; Puustjärvi, T; Teräsvirta, M; Uusitalo, H; Valtonen, P1
Holte, AV; Jensen, AL; Kristensen, AT; Moesgaard, SG; Mogensen, T; Mølbak, J; Olsen, LH; Reynolds, AJ; Teerlink, T1
Ayajiki, K; Gemba, M; Okamura, T; Shinozaki, K; Yamamizu, K1
Carru, C; Carta, F; Deiana, L; Gaspa, L; Pinna, A; Sotgia, S; Zinellu, A; Zinellu, E1
Arikan, E; Guldiken, S; Karadag, CH1
Benndorf, RA; Bierend, A; Böger, GI; Böger, RH; Dumbadze, E; Maas, R; Rudolph, TK; Schwedhelm, E1
Bode-Boger, SM; Ertl, T; Martens-Lobenhoffer, J; Sulyok, E; Vida, G2
Grooteman, MP; Nubé, MJ; Teerlink, T; Twisk, JW; Wauters, IM1
Brooks, ER; Miller, A; Price, HE; Smith, FA; Vicente, FB; Wang, S1
Fliser, D; Kielstein, JT1
Acikel, C; Caglar, K; Cakir, E; Eyileten, T; Kurt, Y; Oguz, Y; Saglam, M; Sonmez, A; Tasar, M; Vural, A; Yenicesu, M; Yilmaz, MI1
Alfthan, G; Juonala, M; Kähönen, M; Laitinen, T; Marniemi, J; Raitakari, OT; Taittonen, L; Viikari, JS1
Moriatis, M; Naidoo, D; Salonikas, C; Sim, AS; Wang, J; Wang, XL; Wilcken, DE1
Asberg, A; Bigonah, A; Hov, GG; Sagen, E1
Boccioletti, V; Cominacini, L; Garbin, U; Manfro, S; Pasini, AF; Stranieri, C1
Carru, C; Deiana, L; Formato, M; Scanu, B; Sotgia, S; Zinellu, A1
Brown, RD; Carlström, M; Edlund, J; Larsson, E; Palm, F; Persson, AE; Sällström, J; Teerlink, T; Wåhlin, N1
Axelsson, J; Caglar, K; Cakir, E; Carrero, JJ; Eyileten, T; Lindholm, B; Oguz, Y; Qureshi, AR; Saglam, M; Sonmez, A; Stenvinkel, P; Vural, A; Yenicesu, M; Yilmaz, MI1
Beer, JC; Cottin, Y; Duvillard, L; Gambert, P; Guilland, JC; Korandji, C; Lagrost, AC; Lorgis, L; Moreau, D; Rochette, L; Sicard, P; Vergely, C; Zeller, M1
Boeger, RH; Deussen, A; Henle, T; Pexa, A; Schwedhelm, E1
Almer, G; Gasser, R; Gruber, HJ; Horejsi, R; Mangge, H; März, W; Mayer, C; Meinitzer, A; Möller, R; Pilz, S; Truschnig-Wilders, M1
Barbara, JA; Hewitson, CL; Mangoni, AA; McAteer-Carr, B; Whiting, MJ; Woodman, RJ1
Arning, E; Bottiglieri, T; Cooke, JP; Dayal, S; Faraci, FM; Kimoto, M; Lentz, SR; Murry, DJ; Rodionov, RN1
Colaianna, M; Corso, G; D'Apolito, O; Paglia, G; Schiavone, S; Trabace, L; Tricarico, F; Zotti, M1
Corso, G; D'Apolito, O; Garofalo, D; Paglia, G; Tricarico, F1
Iversen, J; Strandgaard, S; Wang, D; Wilcox, CS1
Carru, C; Deiana, L; Scanu, B; Sotgia, S; Zinellu, A1
Kiefte-de Jong, JC; Nanayakkara, PW; Olthof, MR; Smulders, YM; Stehouwer, CD; Teerlink, T; ter Wee, PM; Twisk, JW; van Guldener, C; van Ittersum, FJ1
Cignarelli, M; Corso, G; D'Apolito, O; Garofalo, D; Lamacchia, O; Paglia, G; Pilotti, A; Tricarico, F1
Billecke, SS; D'Alecy, LG; Gadegbeku, CA; Jamerson, KA; Perlman, RL; Platel, R; Whitesall, SE1
Surdacki, A1
Akyel, A; Biberoglu, G; Cengel, A; Hasanoglu, A; Kocaman, SA; Sahinarslan, A; Timurkaynak, T1
Cortina, B; del Olmo, JA; Lluch, P; Lluch, S; Mauricio, MD; Rodrigo, JM; Segarra, G; Serra, MA; Vila, JM1
Andrzejak, R; Antonowicz-Juchniewicz, J; Chachaj, A; Dzietczenia, J; Kuliczkowski, K; Mazur, G; Szuba, A; Wróbel, T1
Dhondt, A; Glorieux, G; Leybaert, L; Schepers, E; Vanholder, R1
Drescher, FT; Rauwerda, JA; Richir, MC; Siroen, MP; Teerlink, T; van Leeuwen, PA; Wiest, R; Zorger, N1
Egger, G; Holt, DW; Kiechl, S; Lee, T; Mayr, M; Santer, P; Thompson, G; Tsimikas, S; Willeit, J; Xu, Q1
Goniewicz, ML; Sobczak, A; Szoltysek-Boldys, I1
Brouns, R; De Deyn, PP; Marescau, B; Possemiers, I; Sheorajpanday, R1
Blackwelder, WC; Hazen, SL; Kato, GJ; Machado, RF; Taylor, JG; Wang, Z1
Aucella, F; Boeger, R; Gesualdo, L; Maas, R; Margaglione, M; Schwedhelm, E; Tripepi, G; Vigilante, M; Zoccali, C1
Brennan, DM; Cho, L; Hazen, SL; Tang, WH; Wang, Z1
Blom, H; Carmichael, SL; Finnell, RH; Shaw, GM; Ueland, PM; Vollset, SE; Yang, W1
Bernecker, C; Fauler, G; Fazekas, F; Gruber, HJ; Höbarth, G; Horejsi, R; Lechner, A; Meinitzer, A; Renner, W; Truschnig-Wilders, M; Wallner-Blazek, M; Weiss, S1
Dubiel, JS; Dudek, D; Marewicz, E; Pryjma, J; Rakowski, T; Surdacki, A; Szastak, G; Wieczorek-Surdacka, E1
Mangoni, AA1
Baylis, C; Carson, L; Donley, D; Murphy, EC; Neal, W; Yeater, R1
Francesconi, M; Mittermayer, F; Pleiner, J; Wolzt, M1
Biemond, BJ; Brandjes, DP; Duits, AJ; Landburg, PP; Muskiet, FA; Schnog, JB; Teerlink, T1
Ajtay, Z; Awiszus, F; Bode-Böger, SM; Cziráki, A; Martens-Lobenhoffer, J; Németh, A; Sulyok, E; Szabados, S; Szabó, C1
Artusi, C; Boffa, GM; Ivanova, M; Plebani, M; Zaninotto, M1
Kanazawa, I; Nabika, T; Notsu, Y; Sugimoto, T; Yamaguchi, T; Yano, S2
Bennett, C; Dasarathy, S; Edmison, JM; Kalhan, SC; Kasumov, T; Lopez, R1
Bode-Böger, SM; Bódis, J; Kovács, GL; Martens-Lobenhoffer, J; Sulyok, E; Várnagy, A1
Altun, GD; Aydogdu, N; Gunduz, O; Karadag, H; Kaya, O; Torun, N; Vardar, SA1
Boehm, BO; Drechsler, C; Kielstein, JT; März, W; Meinitzer, A; Pilz, S; Ritz, E; Winkelmann, BR1
Kim, SJ; Lee, SW; Uhm, CS; Yoo, BC1
Gilinsky, MA; Latysheva, TV; Petrakova, GM1
Collin, B; Cottin, Y; Duvillard, L; Goirand, F; Guilland, JC; Korandji, C; Lauzier, B; Moreau, D; Rochette, L; Sicard, P; Vergely, C; Zeller, M1
Blackwell, S; O'Reilly, DS; Reid, D; Talwar, D1
Atzler, D; Benndorf, RA; Böger, RH; Darius, H; Diehm, C; Endres, HG; Lüneburg, N; Maas, R; Schwedhelm, E; Thiem, U; von Stritzky, B1
Beckmann, B; Gutzki, FM; Jordan, J; Tsikas, D1
Ajtay, Z; Alotti, N; Bode-Böger, SM; Cziráki, A; Lenkey, Z; Martens-Lobenhoffer, J; Németh, Á; Sulyok, E; Szabados, S; Szabó, C1
Böger, RH; Schwedhelm, E1
Chen, B; Ji, X; Liang, Y; Wang, Y; Yi, L; Zhang, P; Zhou, Z1
Bucciarelli, T; D'Orazio, N; Felaco, M; Franceschelli, S; Gaeta, R; Grilli, A; Riccioni, G; Speranza, L1
Bode-Böger, SM; Bukowska, A; Ghanem, A; Goette, A; Hammwöhner, M; Klein, HU; Lehmann, HI; Martens-Lobenhoffer, J; Röhl, FW1
Forman, A; Leone, A; Morris, RC; Schmidlin, O; Sebastian, A1
Barreto, DV; Barreto, FC; Eloot, S; Glorieux, G; Liabeuf, S; Massy, Z; Schepers, E; Vanholder, R1
Baek, IH; Chae, JW; Kang, W; Kwon, KI1
Kinugasa, S; Shinohara, K; Wakatsuki, A1
Anderssohn, M; Böger, RH; Fourie, CM; Glyn, MC; Huisman, HW; Lüneburg, N; Malan, L; Malan, NT; Mels, CM; Schutte, AE; Schutte, R; Smith, W; Van Rooyen, JM1
Hsu, CN; Huang, LT; Lau, YT; Lin, CY; Tain, YL1
Abhary, S; Burdon, KP; Craig, JE; Hewitt, AW; Javadiyan, S; Mills, RA; Straga, T; Whiting, MJ1
Billecke, S; Chen, AF; Craig, T; D'Alecy, LG; Haywood, JR; Hinojosa-Laborde, C; Northcott, CA; Patel, KP1
Caplin, B; Leiper, J1
Blom, HJ; Castro, R; Jakobs, C; Janssen, MC; Kluijtmans, LA; Rivera, I; Rocha, MS; Smulders, Y; Tavares de Almeida, I; Teerlink, T1
Barassi, A; Ciociola, F; Colpi, GM; Corsi, MM; Dozio, E; Fermo, I; Finati, E; Ghilardi, F; Melzi d'Eril, GV; Paroni, R1
Kokot, F; Kunsdorf-Wnuk, A; Wnuk, Z1
Barth, S; Cassel, C; Deng, W; Fischer, U; Grässer, FA; Gross, H; Hennard, C; Kremmer, E; Leonhardt, H; Mamiani, A; Masouris, I; Moritz, B; Neuenkirchen, N; Noessner, E; Ostareck, D; Ostareck-Lederer, A; Stober-Grässer, U1
Djindjić, N; Ilić, M; Krstić, N; Mladenović, D; Nicković, J; Nicković, V; Nikolić, J1
Bueno-Betí, C; Hermenegildo, C; Laguna-Fernández, A; Lázaro-Franco, M; Monsalve, E; Novella, S; Sanchís, J; Sobrino, A; Tarín, JJ1
Chan, K; Chen, DB; Ehsanipoor, RM; Fitzmaurice, LE; Fortson, W; Liao, WX; Wing, DA1
Basic, J; Cvetkovic, T; Ilic, A; Ljubisavljevic, S; Pavlovic, D; Pavlovic, R; Stojanovic, I; Stukalov, M; Vojinovic, S1
Böger, R; Breitling, LP; Brenner, H; Koenig, W; Maas, R; Rothenbacher, D; Schwedhelm, E; Siegerink, B; Vossen, CY1
Bartáková, V; Bělobrádková, J; Jurajda, M; Kaňková, K; Klepárník, M; Krusová, D; Kuricová, K; Malúšková, D; Mužík, J; Olšovský, J; Pácal, L; Pavlík, T; Rehořová, J; Stěpánková, S; Svojanovský, J; Tanhäuserová, V; Tomandl, J1
Anderssohn, M; Böger, RH; Frey, N; Lüneburg, N; Lutz, M; Rosenberg, M; Schwedhelm, E; Zugck, C1
Bucciarelli, T; Felaco, M; Franceschelli, S; Gallina, S; Patruno, A; Pesce, M; Riccioni, G; Speranza, L1
Attia, JR; Carru, C; Mangoni, AA; McEvoy, M; Zinellu, A1
Linz, TH; Lunte, SM1
He, H; Jiang, H; Li, X; Liu, X; Liu, Y; Wang, H; Wang, S; Yuan, L; Zhang, W1
Balestrieri, ML; Castaldo, D; Cautela, D; Giovane, A; Servillo, L1
Brykner, R; Cwynar-Zając, Ł; Dzięgiel, P; Ewa Chlebda-Sieragowska, E; Fereniec-Gołębiewska, L; Gomułkiewicz, A; Kwiatkowska, J; Merwid-Ląd, A; Pieśniewska, M; Sozański, T; Szeląg, A; Szuba, A; Trocha, M1
Betz, B; Böger, RH; Kniepert, J; Kress, T; Möller-Ehrlich, K; Sauvant, C; Schneider, R; Schwedhelm, E; Wanner, C1
Davids, M; Teerlink, T1
Agho, K; Attia, J; Carru, C; Hancock, S; Inder, K; Kelly, B; Mangoni, AA; McEvoy, MA; Peel, R; Schofield, P; Smith, W; Soiza, RL; Zinellu, A1
Boeger, RH; Hamer, M; Lambert, GW; Malan, L; Malan, NT; Reimann, M; Schlaich, MP; Ziemssen, T1
Anderssohn, M; Atzler, D; Ayers, CR; Böger, RH; de Lemos, JA; Gore, MO; Grant, PJ; Khera, A; Lüneburg, N; McGuire, DK; Schwedhelm, E1
Cvetkovic, TP; Djordjevic, VM; Paunovic, GJ; Pavlovic, DD; Stefanovic, NZ; Stojanovic, DR; Stojanovic, IR; Velickovic-Radovanovic, RM1
Agho, K; Attia, J; Mangoni, AA; McEvoy, M; Peel, R; Schofield, P; Smith, W; Soiza, RL1
Ajjan, R; Anderssohn, M; Böger, RH; Grant, PJ; Lüneburg, N; McLachlan, S; Price, JF; Robertson, C; Schwedhelm, E; Strachan, MW; Williamson, RM1
De Gennaro Colonna, V; Ferrario, P; Lavanga, V; Pascale, V; Pascale, W; Sansone, V1
Baranyi, A; Kapfhammer, HP; Meinitzer, A; Putz-Bankuti, C; Rothenhäusler, HB; Stauber, R1
Caceres, TB; Chen, J; Chen, X; Gong, Q; Hevel, JM; Liu, L; Peng, J; Shi, Y; Teng, M; Wang, C; Wang, J; Wu, J; Zhang, Z; Zhu, Y; Zuo, X1
Bucciarelli, T; D'Orazio, N; Gallina, S; Riccioni, G; Scotti, L; Speranza, L; Speziale, G1
Bode-Böger, SM; Fliser, D; Kielstein, JT; Schepers, E; Speer, T1
Atzler, D; Böger, RH; Dörr, M; Friedrich, N; Kroemer, HK; Nauck, M; Schwedhelm, E; Völker, U; Völzke, H; Wallaschofski, H1
Huang, YH; Kuo, HC; Lee, CP; Tain, YL1
Atzler, D; Böger, RH; Friedrich, N; Ittermann, T; Nauck, M; Schwedhelm, E1
Bammens, B; Claes, KJ; de Loor, H; Evenepoel, P; Kuypers, DR; Lerut, E; Meijers, B; Naesens, M; Sprangers, B; Vanrenterghem, Y1
Adachi, T; Hakuno, D; Kimura, K; Kujiraoka, T; Masaki, N; Miyazaki, K; Namba, T; Shiraishi, Y; Toya, T; Yada, H1
Gerstoft, J; Kvale, D; Manner, IW; Nielsen, SD; Os, I; Pedersen, KK; Seljeflot, I; Trøseid, M1
Anderssohn, M; Benjamin, EJ; Bernges, I; Blankenberg, S; Böger, RH; Carter, AM; Chen, MH; Erdmann, J; Fornage, M; Gieger, C; Glazer, NL; Grant, PJ; Heckbert, SR; Ikram, MA; Illig, T; Kittel, A; König, IR; König, J; Lackner, K; Lieb, W; Loley, C; Longstreth, WT; Lüneburg, N; Lunetta, KL; Maas, R; Meisinger, C; Munzel, T; Ojeda, FM; Psaty, BM; Schillert, A; Schunkert, H; Schwedhelm, E; Seshadri, S; Smith, N; Sticht, H; Sullivan, LM; Vasan, RS; Wang, TJ; Wichmann, HE; Wiggins, KL; Wild, PS; Xanthakis, V; Zeller, T; Ziegler, A1
Delafontaine, P; Egan, P; Fernandez, C; Giles, TD; Kandavar, R; Kim, C; Roffidal, LE; Sander, GE; Sukhanov, S; Velaga, S1
Lappegård, KT; Nestvold, TK; Nielsen, EW; Seljeflot, I; Thoresen, H; Trøseid, M1
Akar, I; Ince, I; Senol, S; Tekumit, H1
Eisel, UL; Garrelds, IM; Kop, WJ; Mommersteeg, PM; Schalkwijk, CG; Schoemaker, RG1
Borderie, D; Bos, C; Huneau, JF; Magné, J; Mariotti, F; Mathé, V1
Bondesson, U; Egeröd, H; Hedeland, M; Henrohn, D; Sandqvist, A; Wernroth, L; Wikström, G1
Bosco, G; Bucciarelli, T; Bucciarelli, V; Di Ilio, E; Guagnano, MT; Martini, F; Riccioni, G; Scotti, L; Speranza, L1
Auguadro, C; D'Arrigo, G; Grassi, G; Mallamaci, F; Mancia, G; Pizzini, P; Scalise, F; Seravalle, G; Spaziani, D; Trevano, FQ; Tripepi, G; Zoccali, C1
Aldámiz-Echevarria, L; Andrade, F; Couce, ML; de Las Heras, J; Llarena, M1
Aydogdu, N; Cakir, E; Erbas, H; Türksever, A1
Aycan-Ustyol, E; Bekpinar, S; Dinccag, N; Gurdol, F; Unlucerci, Y; Yenidunya, G1
Closs, EI; Longo, A; Palmieri, F; Palmieri, L; Porcelli, V1
Appelbaum, S; Atzler, D; Bauer, C; Blankenberg, S; Böger, RH; Hoffmann, B; Lackner, KJ; Münzel, T; Ojeda, FM; Ramuschkat, M; Schnabel, RB; Schwedhelm, E; Sinning, CR; Wild, PS; Zeller, T1
Amouzadeh-Ghadikolai, O; Baranyi, A; Baranyi, M; Hlade, P; Koppitz, M; Meinitzer, A; Reicht, G; Robier, C; Rothenhäusler, HB; Theokas, S1
Cherkanova, MS; Gilinsky, MA; Sukhovershin, RA1
Bode-Böger, SM; Brilloff, S; Burdin, DV; Demyanov, AV; Hohenstein, B; Jarzebska, N; Martens-Lobenhoffer, J; Rodionov, RN; Weiss, N1
Atzler, D; Bahls, M; Böger, RH; Dörr, M; Felix, SB; Friedrich, N; Ittermann, T; Schwedhelm, E; Völzke, H1
Berardo, C; Di Pasqua, LG; Ferrigno, A; Richelmi, P; Rizzo, V; Vairetti, M1
Bazer, FW; Che, D; Hou, Y; Hu, S; Jia, S; Nawaratna, G; Wang, F; Wu, G1
Prostran, M; Radenkovic, M; Stojanovic, M1
Deveci, F; İn, E; Kaman, D1
Guzman, M; Hasbun, A; Matyksa, MT; Mehr, Z; Modereger, B; Pesek, JJ; Phan, VT; Watanable, S1
Ambrosio, G; Cvetkovic, T; Ilic, MD; Ilic, S; Kocic, G; Lazarevic, G; Pavlovic, R; Zivanovic, S1
Boelaert, J; Eloot, S; Glorieux, G; Lynen, F; Schepers, E; Vanholder, R1
Bestle, MH; Haase, N; Itenov, TS; Johansson, PI; Mortensen, KM; Müller, RB; Olsen, NV; Ostrowski, SR; Perner, A; Søe-Jensen, P1
Atzler, D; Benjamin, EJ; Böger, RH; Ellinor, PT; Larson, MG; Levy, D; Lubitz, SA; Maas, R; Magnani, JW; McManus, DD; Schnabel, RB; Schwedhelm, E; Vasan, RS; Wang, N; Yin, X1
Cervar-Zivkovic, M; Eberhard, K; Kolovetsiou-Kreiner, V; Lang, U; Mayer-Pickel, K; Mörtl, MG; Obermayer-Pietsch, B; Schlembach, D1
Derkacz, A; Doroszko, A; Gutherc, R; Jasiczek, J; Mazur, G; Rola, P; Szahidewicz-Krupska, E; Szymczyszyn, A1
Bifulco, F; Carru, C; Fois, AG; Mangoni, AA; Pirina, P; Sotgia, S; Sotgiu, E; Zinellu, A; Zinellu, E1
Bode-Böger, SM; Bornstein, SR; Brilloff, S; Brocker, C; Burdin, DV; Demyanov, AV; Gonzalez, F; Jarzebska, N; Kolobov, AA; Maas, R; Martens-Lobenhoffer, J; Mieth, M; Rodionov, RN; Samusik, N; Soshnev, AA; Weiss, N1
Atzler, D; Boeing, H; Böger, RH; Cordts, K; di Giuseppe, R; Menzel, J; Schwedhelm, E; Weikert, C; Wirth, J1
Illes, Z; Keki, S; Lantos, J; Menyhei, G; Molnar, T; Nagy, L; Szabo, P; Volgyi, E1
Au Yeung, SL; Lam, HS; Lin, SL; Schooling, CM1
Gaksch, M; Grübler, MR; Kienreich, K; März, W; Meinitzer, A; Müllner, C; Pieske, B; Pilz, S; Richtig, G; Scharnagl, H; Schmid, J; Schwetz, V; Tomaschitz, A; Trummer, C; Verheyen, ND1
Banerjee, T; Coresh, J; Hai, X; Hostetter, TH; Hwang, S; Melamed, ML; Meyer, TW; Powe, NR; Shafi, T1
Bernasconi, L; Christ-Crain, M; Henzen, C; Hoess, C; Huber, A; Kulkarni, P; Meier, MA; Mueller, B; Ottiger, M; Schuetz, P; Steuer, C; Thomann, R; Vögeli, A; Zimmerli, W1
Senol, A; Senol, S1
Bailey, FJ; Lundgren, BR; Moley, G; Nomura, CT1
Bawden, CS; Fraser, CK; Kuchel, TR; Middleton, B; Morton, AJ; Pennings, JL; Rudiger, SR; Skene, DJ1
Hsu, CN; Tain, YL1
Arós, F; Clish, CB; Corella, D; Estruch, R; Fitó, M; Gómez-Gracia, E; Guasch-Ferré, M; Hruby, A; Hu, FB; Lapetra, J; Liang, L; Martínez-González, MA; Romaguera, D; Ros, E; Ruiz-Canela, M; Salas-Salvadó, J; Serra-Majem, L; Toledo, E; Wang, DD; Yu, E1
Singh, SA; Srinivasan, K; Venkatesh, R1
Cvetkovic, T; Stefanovic, N; Stojanovic, D; Stojanovic, M; Velickovic-Radovanovic, R; Zivkovic, N1
Adamiec, R; Dumas, I; Fiodorenko-Dumas, Z; Mastej, K1
Atzler, D; Böger, RH; Chen, P; Chen, Y; Fassett, J; Guo, H; Hu, X; Kwak, D; Liu, X; Lu, Z; Schwedhelm, E; Wang, H; Xu, X; Yue, W; Zhang, P1
Atzler, D; Böger, RH; Huisman, HW; Kruger, R; Malan, L; Malan, NT; Mels, CMC; Schutte, AE; Schwedhelm, E; Smith, W; van Rooyen, JM1
Lackner, HK; Lucovnik, M; Moertl, MG; Papousek, I; Roessler, A; Schmid-Zalaudek, K; Schulter, G1
Bernasconi, L; Christ-Crain, M; Henzen, C; Hoess, C; Huber, A; Meier, MA; Mueller, B; Ottiger, M; Schuetz, P; Steuer, C; Thomann, R; Vögeli, A; Zimmerli, W1
Chen, XP; Hu, XL; Li, MP; Song, PY; Tang, J1
Delrue, W; Dhondt, A; Eloot, S; Glorieux, G; Roels, S; Schepers, E; Van Biesen, W; Vanholder, R1
Burt, MG; Drake, SM; Mangelsdorf, BL; Mangoni, AA; Radhakutty, A; Rowland, A; Smith, MD; Thompson, CH1
Bode-Böger, SM; Emrich, IE; Fliser, D; Heine, GH; Martens-Lobenhoffer, J; Wagenpfeil, S; Zawada, AM1
Bollenbach, A; Savvidou, MD; Tsikas, D1
Bjørke-Jenssen, A; Bjørke-Monsen, AL; Ueland, PM1
Ali-Sisto, T; Honkalampi, K; Koivumaa-Honkanen, H; Lehto, SM; Mäntyselkä, P; Nandania, J; Ruusunen, A; Tolmunen, T; Valkonen-Korhonen, M; Velagapudi, V; Viinamäki, H1
Cahill, LS; Conroy, AL; Elphinstone, R; Gamble, JL; Gazdzinski, LM; Kain, KC; Kalilani-Phiri, L; Madanitsa, M; McDonald, CR; Mwapasa, V; Philson, AC; Sled, JG; Ter Kuile, FO; Zhong, KJY1
Berghold, A; Degoricija, V; Frank, S; Meinitzer, A; Potočnjak, I; Pregartner, G; Radulović, B; Trbušić, M1
Appel, D; Böger, RH; Czorlich, P; Goetz, AE; Hannemann, J; Schwedhelm, E; Seeberger, M1
Bondesson, U; Hedeland, M; Lundgren, J; Rådegran, G; Sandqvist, A; Wikström, G1
Biedroń, M; Butrym, A; Chachaj, A; Fleszar, MG; Gamian, A; Karczewski, M; Krzystek-Korpacka, M; Mazur, G; Rybka, J; Szuba, A; Wiśniewski, J; Wróbel, T1
Chandrasekharan, UM; Elaine Husni, M; Hazen, SL; Wang, S; Wang, Z; Wilson Tang, WH; Wu, Y1
Ağbaş, A; Aitkenhead, H; Çalışkan, S; Canpolat, N; Ekmekçi, H; Mayes, M; Schaefer, F; Sever, L; Shroff, R; Yılmaz, A1
Bjørke-Monsen, AL; Fløtre, CH; Helm, T; Lund, A; Svingen, GFT; Ueland, PM; Varsi, K1
Arós, F; Bullo, M; Clish, C; Cofán, M; Corella, D; Dennis, C; Estruch, R; Fitó, M; Guasch-Ferré, M; Gutiérrez-Bedmar, M; Hu, FB; Lapetra, J; Liang, L; Martínez-González, MA; Papandreou, C; Razquin, C; Romaguera, D; Ros, E; Ruiz-Canela, M; Salas-Salvadó, J; Serra-Majem, L; Sorlí, JV; Toledo, E; Wang, DD; Yu, E1
Brodmann, M; Gary, T; Hackl, G; Hafner, F; Jud, P; Meinitzer, A; Seinost, G; Verheyen, N1
Abdel Rahman, MF; Amir, M; Gad, MZ; Hassanein, SI1
Gordon, AC; Lambden, S; Leiper, J; Piper, S; Tomlinson, J1
Atzler, D; Böger, RH; Choe, CU; Cordts, K; Gerloff, C; Grant, PJ; Grzybowski, R; Hornig, S; Lezius, S; Lüneburg, N; Magnus, T; Neu, A; Schwedhelm, E; Thomalla, G1
Abusoglu, G; Abusoglu, S; Avci, A; Demir, K; Eryavuz, D; Hosaf, M; Unlu, A1
Alcalde, C; Aldámiz-Echevarría, L; Andrade, F; Bueno, MA; Ceberio, L; Couce, ML; de Las Heras, J; Nambo, PS; Núñez-Marcos, S; Villate, O1
Dimitroulas, T; Kitas, GD1
Bollenbach, A; Huneau, JF; Mariotti, F; Tsikas, D1
Baamonde-Laborda, E; Gonzalez-Cabrera, F; Oliva-Damaso, E; Oliva-Damaso, N; Payan, J; Rodriguez-Esparragon, F; Rodriguez-Perez, JC; Santana-Estupiñan, R1
Auge, D; Chafai, A; Fromm, MF; Gessner, A; Maas, R; Mieth, M; Müller, F1
Bednarz-Misa, I; Bronowicka-Szydełko, A; Fleszar, MG; Gacka, M; Gamian, A; Kędzior, K; Krzystek-Korpacka, M; Masłowski, L; Wiśniewski, J; Witkiewicz, W1
Bode-Böger, SM; Jarzebska, N; Mangoni, AA; Martens-Lobenhoffer, J; Rodionov, RN1
Diakowska, D; Fleszar, MG; Gamian, A; Krzystek-Korpacka, M; Wiśniewski, J; Zboch, M1
Bartoszewicz, M; Giebułtowicz, J; Kasprowicz, K; Korytowska, N; Ratkowski, W; Renke, M; Rita-Tkachenko, P; Wołyniec, W; Zorena, K1
Bahls, M; Böger, RH; Büttner, P; Hindricks, G; Kornej, J; Schwedhelm, E; Thiele, H1
Bartha, E; Molnar, T; Nagy, L; Szabo, Z1
Bassu, S; Carru, C; Castagna, F; Erre, GL; Mangoni, AA; Passiu, G; Piga, M; Sotgia, S; Zinellu, A1
Bergia, RE; Campbell, WW; Kim, JE; Roseguini, BT1
Doroszko, A; Fortuna, P; Gajecki, D; Gawryś, J; Gawryś, K; Leśniewska, J; Majda, F; Mlynarz, P; Szahidewicz-Krupska, E; Wiśniewski, J1
Bollinger, L; Ertelt, A; Gehlen, H; Kuban, S; Liertz, S; Merle, R; Stumpff, F1
Lynch, KL; van Wijk, XMR; Yun, C1
Appel, D; Böger, R; Czorlich, P; Haddad, M; Hannemann, J; Lamszus, K; Mader, MM; Mohme, M; Schwedhelm, E; Westphal, M1
Adamiec, R; Dumas, I; Fiodorenko-Dumas, Z; Małecki, R; Paprocka-Borowicz, M; Rabczynski, M1
Abuşoğlu, G; Akdağ, T; Dursunoğlu, D; Kaynar, M; Saygın, Y; Sivrikaya, A; Ünlü, A1
Alptekin, H; Karaman, S; Onmaz, DE; Sivrikaya, A1
Bakker, SJL; Bollenbach, A; Post, A; Tsikas, D1
Couderc, F; Koval, D; Sommerová, B; Tůma, P1
Balfanz, P; Böger, R; Dahl, E; Dreher, M; Hannemann, J; Hartmann, B; Marx, N; Müller-Wieland, D; Schwedhelm, E; Ule, J1
Asıl, M; Kebapçılar, L; Korkmaz, H; Öztürk, B; Temel, T1
Attia, JR; Hancock, SJ; Holliday, E; Mangoni, AA; McEvoy, MA; Oldmeadow, C; Peel, R; Smith, WT; Talley, NJ; Walker, MM1
Atzler, D; Böger, RH; Duncan, MS; Hannemann, J; Maas, R; Moser, C; Schwedhelm, E; Vasan, RS; Xanthakis, V; Yola, IM1
Bosch, A; Fromm, MF; Gemeinhardt, A; Gessner, A; Kannenkeril, D; Maas, R; Mayr, A; Schmieder, RE; Staerk, C1
Beckmann, B; Brinkmann, F; Dillenhöfer, S; Frank, M; Hamelmann, E; Hanusch, B; Holtmann, M; Jöckel, KH; Koerner-Rettberg, C; Langrock, C; Legenbauer, T; Lücke, T; Maasjosthusmann, P; Reinehr, T; Sinningen, K; Tsikas, D1
Bonnitcha, P; Fitzpatrick, M; Ireland, A; Koay, YC; Nguyen, VL; O'Sullivan, J; Sullivan, D1
Doğan, Ö; Haşimi, A; Serdar, CC; Serdar, MA1
Drapała, A; Samborowska, E; Szlęzak, D; Ufnal, M; Wróbel, M1

Reviews

13 review(s) available for n,n-dimethylarginine and symmetric dimethylarginine

ArticleYear
The lung in the balance: arginine, methylated arginines, and nitric oxide.
    American journal of physiology. Lung cellular and molecular physiology, 2007, Volume: 292, Issue:1

    Topics: Animals; Arginine; Humans; Lung; Methylation; Models, Biological; Nitric Oxide; omega-N-Methylarginine; Protein-Arginine N-Methyltransferases

2007
Protein arginine methylation: Cellular functions and methods of analysis.
    Biochimica et biophysica acta, 2006, Volume: 1764, Issue:12

    Topics: Arginine; DNA Repair; F-Box Proteins; Humans; Mass Spectrometry; Methyltransferases; Protein Processing, Post-Translational; Protein-Arginine N-Methyltransferases; Proteomics; RNA Processing, Post-Transcriptional; S-Adenosylmethionine; Signal Transduction; Transcription, Genetic

2006
L-arginine analogs--inactive markers or active agents in atherogenesis?
    Cardiovascular & hematological agents in medicinal chemistry, 2008, Volume: 6, Issue:4

    Topics: Arginine; Atherosclerosis; Biomarkers; Coronary Disease; Endothelium, Vascular; Humans; Inflammation; Nitric Oxide; Oxidative Stress

2008
The emerging role of symmetric dimethylarginine in vascular disease.
    Advances in clinical chemistry, 2009, Volume: 48

    Topics: Arginine; Cardiovascular Diseases; Homeostasis; Humans; Nitric Oxide; Nitric Oxide Synthase Type III; Renal Insufficiency

2009
The role of asymmetric and symmetric dimethylarginines in renal disease.
    Nature reviews. Nephrology, 2011, Volume: 7, Issue:5

    Topics: Arginine; Humans; Kidney; Renal Insufficiency, Chronic; Risk Factors

2011
Endogenous nitric oxide synthase inhibitors in the biology of disease: markers, mediators, and regulators?
    Arteriosclerosis, thrombosis, and vascular biology, 2012, Volume: 32, Issue:6

    Topics: Amidohydrolases; Animals; Arginine; Binding Sites; Binding, Competitive; Biomarkers; Cardiovascular Agents; Cardiovascular Diseases; Catalytic Domain; Enzyme Inhibitors; Humans; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine

2012
Dimethylarginines ADMA and SDMA: the real water-soluble small toxins?
    Seminars in nephrology, 2014, Volume: 34, Issue:2

    Topics: Arginine; Biomarkers; Cardiovascular Diseases; Humans; Kidney Diseases; Water

2014
Endothelial Dysfunction in Renal Failure: Current Update.
    Current medicinal chemistry, 2016, Volume: 23, Issue:19

    Topics: Arginine; Endothelium, Vascular; Humans; Nitric Oxide; Oxidative Stress; Renal Insufficiency; Uremia; Vascular Cell Adhesion Molecule-1; Vitamin D Deficiency

2016
Toxic Dimethylarginines: Asymmetric  Dimethylarginine (ADMA) and Symmetric  Dimethylarginine (SDMA).
    Toxins, 2017, 03-06, Volume: 9, Issue:3

    Topics: Animals; Arginine; Humans; Toxins, Biological

2017
AGXT2: An unnegligible aminotransferase in cardiovascular and urinary systems.
    Journal of molecular and cellular cardiology, 2017, Volume: 113

    Topics: Animals; Arginine; Cardiovascular Diseases; Cardiovascular System; Humans; Kidney Diseases; Transaminases

2017
Genetic regulation of dimethylarginines and endothelial dysfunction in rheumatoid arthritis.
    Amino acids, 2019, Volume: 51, Issue:7

    Topics: Arginine; Arthritis, Rheumatoid; Atherosclerosis; Biomarkers; Cardiovascular Diseases; Endothelium, Vascular; Humans; Inflammation; Nitric Oxide; Nitric Oxide Synthase; Polymorphism, Single Nucleotide; Transaminases

2019
Asymmetric (ADMA) and Symmetric (SDMA) Dimethylarginines in Chronic Kidney Disease: A Clinical Approach.
    International journal of molecular sciences, 2019, Jul-26, Volume: 20, Issue:15

    Topics: Aging; Animals; Arginine; Cardiovascular Diseases; Endothelium, Vascular; Humans; Metabolic Networks and Pathways; Molecular Targeted Therapy; Prognosis; Renal Dialysis; Renal Insufficiency, Chronic

2019
The Second Life of Methylarginines as Cardiovascular Targets.
    International journal of molecular sciences, 2019, Sep-17, Volume: 20, Issue:18

    Topics: Amidohydrolases; Animals; Arginine; Biological Transport; Biomarkers; Cardiovascular Diseases; Cardiovascular System; Disease Susceptibility; Energy Metabolism; Humans; Molecular Targeted Therapy

2019

Trials

19 trial(s) available for n,n-dimethylarginine and symmetric dimethylarginine

ArticleYear
Endothelium-dependent vasodilation is independent of the plasma L-arginine/ADMA ratio in men with stable angina: lack of effect of oral L-arginine on endothelial function, oxidative stress and exercise performance.
    Journal of the American College of Cardiology, 2001, Volume: 38, Issue:2

    Topics: Administration, Oral; Angina Pectoris; Arginine; Dinoprost; Double-Blind Method; Endothelium, Vascular; Exercise; Exercise Test; F2-Isoprostanes; Forearm; Heart Rate; Humans; Injections, Intra-Arterial; Male; Middle Aged; Oxidative Stress; Regional Blood Flow; Vasodilation

2001
Asymmetric dimethylarginine determines the improvement of endothelium-dependent vasodilation by simvastatin: Effect of combination with oral L-arginine.
    Journal of the American College of Cardiology, 2007, Jun-12, Volume: 49, Issue:23

    Topics: Aged; Aged, 80 and over; Arginine; C-Reactive Protein; Drug Therapy, Combination; Endothelium, Vascular; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lipoproteins; Male; Middle Aged; Nitric Oxide Synthase Type III; Simvastatin; Vasodilation

2007
Plasma dimethylarginine levels in chronic hemodialysis patients are independent of the type of dialyzer applied.
    Blood purification, 2007, Volume: 25, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Arginine; beta 2-Microglobulin; Biocompatible Materials; Complement C3a; Cross-Over Studies; Equipment Design; Female; Humans; Kidney Failure, Chronic; Male; Membranes, Artificial; Middle Aged; Nitric Oxide; Prospective Studies; Renal Dialysis

2007
Improving proteinuria, endothelial functions and asymmetric dimethylarginine levels in chronic kidney disease: ramipril versus valsartan.
    Blood purification, 2007, Volume: 25, Issue:4

    Topics: Adult; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Arginine; Biomarkers; Blood Glucose; C-Reactive Protein; Female; Glomerular Filtration Rate; Hemorheology; Humans; Insulin Resistance; Kidney Failure, Chronic; Lipids; Male; Middle Aged; Proteinuria; Ramipril; Renin-Angiotensin System; Tetrazoles; Valine; Valsartan; Vasodilation

2007
Randomized placebo-controlled trial assessing a treatment strategy consisting of pravastatin, vitamin E, and homocysteine lowering on plasma asymmetric dimethylarginine concentration in mild to moderate CKD.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2009, Volume: 53, Issue:1

    Topics: Adult; Aged; Anticholesteremic Agents; Arginine; Carotid Arteries; Chronic Disease; Creatinine; Double-Blind Method; Female; Folic Acid; Homocysteine; Humans; Kidney Diseases; Lipoproteins, LDL; Male; Middle Aged; Pravastatin; Vitamin B 12; Vitamin B 6; Vitamin E

2009
Effects of an exercise intervention using Dance Dance Revolution on endothelial function and other risk factors in overweight children.
    International journal of pediatric obesity : IJPO : an official journal of the International Association for the Study of Obesity, 2009, Volume: 4, Issue:4

    Topics: Arginine; Biomarkers; Blood Glucose; Blood Pressure; Body Height; Body Mass Index; Body Weight; Brachial Artery; Child; Dance Therapy; Endothelium, Vascular; Exercise Therapy; Female; Humans; Inflammation Mediators; Insulin; Lipids; Male; Nitrates; Nitrites; Overweight; Oxygen Consumption; Patient Compliance; Physical Fitness; Risk Factors; Time Factors; Treatment Outcome; Ultrasonography; Vasodilation; Video Games

2009
Treatment with alpha-lipoic acid reduces asymmetric dimethylarginine in patients with type 2 diabetes mellitus.
    Translational research : the journal of laboratory and clinical medicine, 2010, Volume: 155, Issue:1

    Topics: Arginine; Diabetes Mellitus, Type 2; Double-Blind Method; Female; Humans; Male; Middle Aged; Thioctic Acid

2010
Symmetrical and asymmetrical dimethylarginine as predictors for mortality in patients referred for coronary angiography: the Ludwigshafen Risk and Cardiovascular Health study.
    Clinical chemistry, 2011, Volume: 57, Issue:1

    Topics: Aged; Arginine; Biomarkers; Cardiovascular Diseases; Coronary Angiography; Coronary Disease; Female; Humans; Linear Models; Male; Middle Aged; Mortality; Predictive Value of Tests; Prognosis; Renal Insufficiency; Risk Factors

2011
Salt sensitivity in blacks: evidence that the initial pressor effect of NaCl involves inhibition of vasodilatation by asymmetrical dimethylarginine.
    Hypertension (Dallas, Tex. : 1979), 2011, Volume: 58, Issue:3

    Topics: Adult; Arginine; Black or African American; Blood Pressure; Dose-Response Relationship, Drug; Female; Hemodynamics; Humans; Hypertension; Male; Middle Aged; Sodium Chloride, Dietary; Time Factors; Vascular Resistance; Vasodilation

2011
The biological evaluation of ADMA/SDMA and eNOS in patients with ACHF.
    Frontiers in bioscience (Elite edition), 2013, 01-01, Volume: 5, Issue:2

    Topics: Adult; Aged; Alanine Transaminase; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Arginine; Aspartate Aminotransferases; Blotting, Western; Chromatography, High Pressure Liquid; Digoxin; Diuretics; Echocardiography; Electron Transport Complex IV; Female; Heart Failure; Humans; Kidney Function Tests; Leukocytes, Mononuclear; Male; Middle Aged; Nitric Oxide Synthase Type III; Oxygen

2013
Digital plethysmography and arginine metabolism in prehypertension: effect of nebivolol therapy.
    Journal of clinical hypertension (Greenwich, Conn.), 2015, Volume: 17, Issue:1

    Topics: Adult; Antihypertensive Agents; Arginine; Benzopyrans; Blood Pressure; Citrulline; Endothelium, Vascular; Ethanolamines; Female; Humans; Male; Middle Aged; Nebivolol; Nitric Oxide; Plethysmography; Prehypertension; Prospective Studies; Regional Blood Flow

2015
Changes in plasma levels of asymmetric dimethylarginine, symmetric dimethylarginine, and arginine after a single dose of vardenafil in patients with pulmonary hypertension.
    Vascular pharmacology, 2015, Volume: 73

    Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Arginine; Atrial Function, Right; Atrial Pressure; Biomarkers; Cardiac Output; Female; Humans; Hypertension, Pulmonary; Male; Middle Aged; Phosphodiesterase 5 Inhibitors; Time Factors; Treatment Outcome; Vardenafil Dihydrochloride; Vasodilator Agents

2015
Asymmetric and Symmetric Dimethylarginine and Sympathetic Nerve Traffic after Renal Denervation in Patients with Resistant Hypertension.
    Clinical journal of the American Society of Nephrology : CJASN, 2015, Sep-04, Volume: 10, Issue:9

    Topics: Aged; Arginine; Blood Pressure; Drug Resistance; Female; Heart Rate; Humans; Hypertension; Longitudinal Studies; Male; Middle Aged; Muscle, Skeletal; Sympathectomy; Sympathetic Nervous System

2015
Effect of the transdermal low-level laser therapy on endothelial function.
    Lasers in medical science, 2016, Volume: 31, Issue:7

    Topics: Adult; Angiostatins; Arginine; Female; Fibroblast Growth Factors; Glutathione; Humans; Lasers, Semiconductor; Low-Level Light Therapy; Male; Nitric Oxide; Vascular Endothelial Growth Factor A

2016
Effects of Vitamin D3 on asymmetric- and symmetric dimethylarginine in arterial hypertension.
    The Journal of steroid biochemistry and molecular biology, 2018, Volume: 175

    Topics: Aged; Analysis of Variance; Arginine; Blood Pressure; Cholecalciferol; Dietary Supplements; Double-Blind Method; Female; Humans; Hypertension; Male; Middle Aged; Vitamin D; Vitamin D Deficiency

2018
Serum Asymmetric and Symmetric Dimethylarginine and Morbidity and Mortality in Hemodialysis Patients.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2017, Volume: 70, Issue:1

    Topics: Arginine; Cardiovascular Diseases; Female; Humans; Male; Middle Aged; Morbidity; Prospective Studies; Renal Dialysis

2017
Hemodiafiltration is associated with reduced inflammation, oxidative stress and improved endothelial risk profile compared to high-flux hemodialysis in children.
    PloS one, 2018, Volume: 13, Issue:6

    Topics: Adolescent; Arginine; Biomarkers; Child; Female; Hemodiafiltration; Humans; Inflammation; Male; Oxidative Stress; Prospective Studies; Treatment Outcome

2018
A high-protein meal does not improve blood pressure or vasoactive biomarker responses to acute exercise in humans.
    Nutrition research (New York, N.Y.), 2020, Volume: 81

    Topics: Adult; Arginine; Biomarkers; Blood Pressure; Cross-Over Studies; Dietary Fats; Dietary Proteins; Double-Blind Method; Exercise; Female; Humans; Male; Meals; Postprandial Period

2020
Effects of treatment with SGLT-2 inhibitors on arginine-related cardiovascular and renal biomarkers.
    Cardiovascular diabetology, 2022, 01-06, Volume: 21, Issue:1

    Topics: Arginine; Benzhydryl Compounds; Biomarkers; Blood Glucose; Cross-Over Studies; Diabetes Mellitus, Type 2; Double-Blind Method; Female; Glucosides; Glycated Hemoglobin; Humans; Male; Middle Aged; Predictive Value of Tests; Prospective Studies; Sodium-Glucose Transporter 2 Inhibitors; Time Factors; Treatment Outcome

2022

Other Studies

197 other study(ies) available for n,n-dimethylarginine and symmetric dimethylarginine

ArticleYear
Urinary excretion of dimethylarginines in premature infants.
    Biochemical medicine, 1984, Volume: 32, Issue:2

    Topics: Adolescent; Adult; Aging; Arginine; Body Weight; Child; Child, Preschool; Diet; Gestational Age; Humans; Infant; Infant, Newborn; Infant, Premature; Male; Methylhistidines; Muscle Proteins; Nitrogen; Proteins

1984
Urinary excretion of NG-dimethylarginines in multiple sclerosis patients: preliminary observations.
    Journal of the neurological sciences, 1995, Volume: 129, Issue:2

    Topics: Arginine; Case-Control Studies; Chromatography, High Pressure Liquid; Humans; Multiple Sclerosis; Reference Values; Sensitivity and Specificity

1995
Nitric oxide synthase inhibitors and hypertension in children and adolescents.
    Journal of hypertension, 1997, Volume: 15, Issue:8

    Topics: Adolescent; Animals; Arginine; Child; Endothelium, Vascular; Enzyme Inhibitors; Female; Glomerular Filtration Rate; Humans; Hypertension; Hypertension, Renal; Hypertension, Renovascular; In Vitro Techniques; Male; Mice; Muscle Contraction; Nitric Oxide Synthase; omega-N-Methylarginine; Phenylephrine; Renin; Vasoconstrictor Agents

1997
Serum concentrations of asymmetric (ADMA) and symmetric (SDMA) dimethylarginine in renal failure patients.
    Kidney international. Supplement, 2001, Volume: 78

    Topics: Adult; Aged; Amino Acids; Arginine; Blood Pressure; Case-Control Studies; Creatinine; Female; Humans; Kidney Failure, Chronic; Kidney Transplantation; Male; Middle Aged; Renal Dialysis

2001
Increased reduction of dimethylarginines and lowered interdialytic blood pressure by the use of biocompatible membranes.
    Kidney international. Supplement, 2001, Volume: 78

    Topics: Adult; Aged; Arginine; beta 2-Microglobulin; Biocompatible Materials; Blood Pressure; Diabetic Nephropathies; Female; Hematocrit; Hemodiafiltration; Hemoglobins; Humans; Kidney Failure, Chronic; Kidneys, Artificial; Male; Membranes, Artificial; Middle Aged; Renal Dialysis; Urea

2001
Homocysteine impairs the nitric oxide synthase pathway: role of asymmetric dimethylarginine.
    Circulation, 2001, Nov-20, Volume: 104, Issue:21

    Topics: Amidohydrolases; Animals; Aorta; Arginine; Arteriosclerosis; Cattle; Cell Line; Culture Techniques; Endothelium, Vascular; Homocysteine; Hydrolases; Hyperhomocysteinemia; Kinetics; Methionine; Nitric Oxide; Nitric Oxide Synthase; Recombinant Fusion Proteins; Signal Transduction

2001
Endogenous nitric oxide synthase inhibitors in endothelial cells, endothelin-1 within the vessel wall, and intimal hyperplasia in perimenopausal human uterine arteries.
    Journal of cardiovascular pharmacology, 2002, Volume: 39, Issue:2

    Topics: Adult; Arginine; Arteries; Chromatography, High Pressure Liquid; Climacteric; Cyclic GMP; Endothelin-1; Endothelium, Vascular; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Female; Humans; Hyperplasia; In Vitro Techniques; Middle Aged; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Tunica Intima; Tunica Media; Uterus

2002
Probucol preserves endothelial function by reduction of the endogenous nitric oxide synthase inhibitor level.
    British journal of pharmacology, 2002, Volume: 135, Issue:5

    Topics: Animals; Aorta, Thoracic; Arginine; Endothelium, Vascular; Enzyme Inhibitors; Lipoproteins, LDL; Male; Malondialdehyde; Muscle, Smooth, Vascular; Nitric Oxide Synthase; Probucol; Rats; Rats, Sprague-Dawley; Vasodilation

2002
Impaired nitric oxide synthase pathway in diabetes mellitus: role of asymmetric dimethylarginine and dimethylarginine dimethylaminohydrolase.
    Circulation, 2002, Aug-20, Volume: 106, Issue:8

    Topics: Amidohydrolases; Animals; Antioxidants; Aorta; Arginine; Cell Line; Cells, Cultured; Cyclic GMP; Diabetes Mellitus, Experimental; Endothelium, Vascular; Enzyme Inhibitors; Glucose; Humans; Male; Muscle, Smooth, Vascular; Nitric Oxide Synthase; Oxidative Stress; Polyethylene Glycols; Rats; Rats, Sprague-Dawley; Superoxide Dismutase

2002
High-performance liquid chromatographic assay of asymmetric dimethylarginine, symmetric dimethylarginine, and arginine in human plasma by derivatization with naphthalene-2,3-dicarboxaldehyde.
    Analytical biochemistry, 2003, Jul-01, Volume: 318, Issue:1

    Topics: Arginine; Cardiovascular Diseases; Chromatography, High Pressure Liquid; Humans; Indicators and Reagents; Naphthalenes; Reference Standards; Reproducibility of Results; Spectrometry, Fluorescence; Stereoisomerism

2003
Asymmetric dimethylarginine and total homocysteine in plasma after oral methionine loading.
    Scandinavian journal of clinical and laboratory investigation, 2003, Volume: 63, Issue:5

    Topics: Administration, Oral; Adult; Arginine; Homocysteine; Humans; Male; Methionine; Middle Aged; Time Factors

2003
Asymmetric dimethylarginine is not elevated in exfoliation syndrome but symmetric dimethylarginine is related to exfoliative glaucoma.
    Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2007, Volume: 245, Issue:2

    Topics: Aged; Arginine; Chromatography, High Pressure Liquid; Cross-Sectional Studies; Exfoliation Syndrome; Female; Glaucoma; Homocysteine; Humans; Male; Oxidative Stress; Prospective Studies

2007
Effects of breed, gender, exercise and white-coat effect on markers of endothelial function in dogs.
    Research in veterinary science, 2007, Volume: 82, Issue:3

    Topics: Alaska; Animals; Arginine; Biomarkers; Color; Dogs; Endothelium; Enzyme Inhibitors; Female; Gene Expression Regulation; Hair; Male; Nitric Oxide; Physical Conditioning, Animal; Sex Characteristics; von Willebrand Factor

2007
Oral administration of both tetrahydrobiopterin and L-arginine prevents endothelial dysfunction in rats with chronic renal failure.
    Journal of cardiovascular pharmacology, 2007, Volume: 49, Issue:3

    Topics: Acetylcholine; Administration, Oral; Animals; Aorta; Arginine; Biopterins; Blood Pressure; Calcimycin; Drug Synergism; Drug Therapy, Combination; Endothelium, Vascular; Kidney Failure, Chronic; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type III; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Superoxides

2007
High-throughput CZE-UV determination of arginine and dimethylated arginines in human plasma.
    Electrophoresis, 2007, Volume: 28, Issue:12

    Topics: Arginine; Electrophoresis, Capillary; Homoarginine; Humans; Plasma; Spectrophotometry, Ultraviolet

2007
Asymmetric dimethylarginine levels in thyroid diseases.
    Journal of endocrinological investigation, 2007, Volume: 30, Issue:3

    Topics: Adult; Arginine; Biomarkers; Female; Humans; Hyperthyroidism; Hypothyroidism; Male; Middle Aged; Thyroid Diseases

2007
Plasma asymmetric dimethylarginine concentration during the perinatal period.
    Neonatology, 2007, Volume: 92, Issue:1

    Topics: Adult; Arginine; Blood Circulation; Endothelium, Vascular; Female; Humans; Infant, Newborn; Nitric Oxide; Nitric Oxide Synthase; Placental Circulation; Postpartum Period; Pregnancy; Pregnancy Trimester, Third

2007
Measurement of arginine derivatives in pediatric patients with chronic kidney disease using high-performance liquid chromatography-tandem mass spectrometry.
    Clinical chemistry and laboratory medicine, 2007, Volume: 45, Issue:10

    Topics: Adolescent; Arginine; Biomarkers; Case-Control Studies; Child; Chromatography, High Pressure Liquid; Female; Humans; Kidney Failure, Chronic; Male; Reproducibility of Results; Sensitivity and Specificity; Siblings; Tandem Mass Spectrometry; Time Factors

2007
Lowering asymmetric dimethylarginine--a new mechanism mediating the renoprotective effects of renin-angiotensin system inhibitors in proteinuric patients?
    Blood purification, 2007, Volume: 25, Issue:4

    Topics: Amidohydrolases; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Arginine; Biomarkers; Hemorheology; Humans; Kidney; Kidney Failure, Chronic; Proteinuria; Rats; Renin-Angiotensin System; Vasodilation

2007
Brachial artery flow-mediated dilation and asymmetrical dimethylarginine in the cardiovascular risk in young Finns study.
    Circulation, 2007, Sep-18, Volume: 116, Issue:12

    Topics: Adult; Arginine; Biomarkers; Brachial Artery; Cardiovascular Diseases; Cross-Sectional Studies; Endothelium, Vascular; Female; Finland; Follow-Up Studies; Hemorheology; Humans; Male; Nitric Oxide Synthase Type III; Oxidative Stress; Risk; Sampling Studies; Vasodilation

2007
Relations between markers of renal function, coronary risk factors and the occurrence and severity of coronary artery disease.
    Atherosclerosis, 2008, Volume: 197, Issue:2

    Topics: Age Factors; Aged; Arginine; Biomarkers; Cohort Studies; Coronary Artery Disease; Cystatin C; Cystatins; Female; Glomerular Filtration Rate; Homocysteine; Humans; Male; Middle Aged; Renal Insufficiency; Risk Factors

2008
Health-associated reference values for arginine, asymmetric dimethylarginine (ADMA) and symmetric dimethylarginine (SDMA) measured with high-performance liquid chromatography.
    Scandinavian journal of clinical and laboratory investigation, 2007, Volume: 67, Issue:8

    Topics: Adult; Age Distribution; Aged; Arginine; Chromatography, High Pressure Liquid; Female; Health; Humans; Male; Middle Aged; Reference Values

2007
Nebivolol reduces asymmetric dimethylarginine in endothelial cells by increasing dimethylarginine dimethylaminohydrolase 2 (DDAH2) expression and activity.
    Pharmacological research, 2007, Volume: 56, Issue:6

    Topics: Adrenergic beta-Antagonists; Amidohydrolases; Antihypertensive Agents; Arginine; Atenolol; Benzopyrans; Cell Line; Endothelial Cells; Ethanolamines; Female; Humans; Male; Nebivolol; Nitric Oxide Synthase Type III; RNA, Messenger

2007
Assessment of protein-incorporated arginine methylation in biological specimens by CZE UV-detection.
    Electrophoresis, 2007, Volume: 28, Issue:23

    Topics: Arginine; Blood Proteins; Cells, Cultured; Electrophoresis, Capillary; Endothelium, Vascular; Feasibility Studies; Humans; Methylation; Protein Processing, Post-Translational; Protein-Arginine N-Methyltransferases; Proteins; Sensitivity and Specificity; Specimen Handling; Spectrophotometry, Ultraviolet; Umbilical Veins

2007
Role of nitric oxide deficiency in the development of hypertension in hydronephrotic animals.
    American journal of physiology. Renal physiology, 2008, Volume: 294, Issue:2

    Topics: Animals; Arginine; Blood Pressure; Disease Models, Animal; Diuresis; Enzyme Inhibitors; Hydronephrosis; Hypertension; Indazoles; Kidney; Kidney Cortex; Kidney Tubules, Proximal; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type III; Potassium; Rats; Rats, Sprague-Dawley; Sodium; Sodium Chloride, Dietary; Ureteral Obstruction

2008
ADMA levels correlate with proteinuria, secondary amyloidosis, and endothelial dysfunction.
    Journal of the American Society of Nephrology : JASN, 2008, Volume: 19, Issue:2

    Topics: Adult; Amyloidosis; Arginine; Chronic Disease; Endothelium; Female; Glomerulonephritis; Humans; Male; Multivariate Analysis; Predictive Value of Tests; Proteinuria; Risk Factors

2008
Impact of asymmetric dimethylarginine on mortality after acute myocardial infarction.
    Arteriosclerosis, thrombosis, and vascular biology, 2008, Volume: 28, Issue:5

    Topics: Aged; Aged, 80 and over; Arginine; Biomarkers; Cohort Studies; Female; Follow-Up Studies; Humans; Male; Middle Aged; Myocardial Infarction; Predictive Value of Tests; Prognosis; Prospective Studies; Regression Analysis

2008
Effects of moderate hyperhomocysteinaemia induced by 4 weeks methionine-enriched diet on metabolite profile and mesenteric artery function in rats.
    The British journal of nutrition, 2008, Volume: 99, Issue:5

    Topics: Animals; Arginine; Biomarkers; Cardiovascular Diseases; Chromatography, High Pressure Liquid; Diet; Homocysteine; Hyperhomocysteinemia; Male; Mesenteric Arteries; Methionine; Rats; Rats, Wistar; Vasodilation

2008
Asymmetric dimethylarginine (ADMA) is tightly correlated with growth in juveniles without correlations to obesity related disorders.
    Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association, 2008, Volume: 116, Issue:9

    Topics: Adolescent; Alkaline Phosphatase; Arginine; Atherosclerosis; Blood Pressure; Body Mass Index; Child; Female; Growth; Humans; Male; Obesity; Reference Values; Regression Analysis; Young Adult

2008
Symmetric dimethylarginine is an independent predictor of intradialytic hypotension.
    American journal of hypertension, 2008, Volume: 21, Issue:8

    Topics: Aged; Arginine; Biomarkers; Blood Pressure; Female; Humans; Hypotension; Kidney Failure, Chronic; Male; Middle Aged; omega-N-Methylarginine; Predictive Value of Tests; Renal Dialysis

2008
Tissue-specific downregulation of dimethylarginine dimethylaminohydrolase in hyperhomocysteinemia.
    American journal of physiology. Heart and circulatory physiology, 2008, Volume: 295, Issue:2

    Topics: Amidohydrolases; Animals; Arginine; Carotid Arteries; Cell Line; Cystathionine beta-Synthase; Disease Models, Animal; Dose-Response Relationship, Drug; Down-Regulation; Endothelial Cells; Endothelium, Vascular; Folic Acid; Gene Expression Regulation, Enzymologic; Homocysteine; Hyperhomocysteinemia; Liver; Methionine; Methylation; Mice; Mice, Inbred C57BL; Mice, Knockout; Nitric Oxide; RNA, Messenger; Vasodilation; Vasodilator Agents

2008
Determination of dimethylarginine levels in rats using HILIC-MS/MS: an in vivo microdialysis study.
    Journal of separation science, 2008, Volume: 31, Issue:13

    Topics: Animals; Arginine; Chromatography, Liquid; Enzyme Inhibitors; Microdialysis; Nitric Oxide Synthase; Prefrontal Cortex; Rats; Rats, Wistar; Reference Standards; Tandem Mass Spectrometry

2008
Evaluation of mobile phase, ion pairing, and temperature influence on an HILIC-MS/MS method for L-arginine and its dimethylated derivatives detection.
    Journal of separation science, 2008, Volume: 31, Issue:13

    Topics: Acrylonitrile; Arginine; Blood Chemical Analysis; Chromatography, Liquid; Indicators and Reagents; Reference Standards; Tandem Mass Spectrometry; Temperature; Trifluoroacetic Acid

2008
Asymmetric dimethylarginine, oxidative stress, and vascular nitric oxide synthase in essential hypertension.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2009, Volume: 296, Issue:2

    Topics: Adult; Arginine; Blood Pressure; Buttocks; Endothelium-Dependent Relaxing Factors; Female; Humans; Hypertension; Linoleic Acids; Lipid Peroxidation; Male; Microvessels; Middle Aged; Nitric Oxide; Nitric Oxide Synthase; Oxidative Stress; Subcutaneous Tissue; Up-Regulation; Vasodilation; Young Adult

2009
Determination of protein-incorporated methylated arginine reference values in healthy subjects whole blood and evaluation of factors affecting protein methylation.
    Clinical biochemistry, 2008, Volume: 41, Issue:14-15

    Topics: Adult; Aged; Aged, 80 and over; Arginine; Female; Health; Humans; Male; Methylation; Middle Aged; omega-N-Methylarginine; Proteins; Reference Values; Regression Analysis

2008
Development and validation of a fast quantitative method for plasma dimethylarginines analysis using liquid chromatography-tandem mass spectrometry.
    Clinical biochemistry, 2008, Volume: 41, Issue:16-17

    Topics: Arginine; Calibration; Chromatography, Liquid; Humans; Quality Control; Reproducibility of Results; Tandem Mass Spectrometry

2008
Blood content of asymmetric dimethylarginine: new insights into its dysregulation in renal disease.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2009, Volume: 24, Issue:2

    Topics: Adult; Arginine; Biomarkers; Case-Control Studies; Erythrocytes; Female; Humans; Hypertension; Kidney Failure, Chronic; Male; Middle Aged; Peptide Hydrolases; Plasma

2009
Asymmetric dimethylarginine and coronary collateral vessel development.
    Coronary artery disease, 2008, Volume: 19, Issue:7

    Topics: Adult; Aged; Arginine; Biomarkers; Collateral Circulation; Coronary Angiography; Coronary Circulation; Coronary Stenosis; Female; Humans; Male; Middle Aged; Odds Ratio

2008
Unchanged plasma levels of dimethylarginines and nitric oxide in chronic hepatitis C.
    Scandinavian journal of gastroenterology, 2009, Volume: 44, Issue:2

    Topics: Adult; Antiviral Agents; Arginine; Case-Control Studies; Female; Hepatitis C, Chronic; Humans; Interferon alpha-2; Interferon-alpha; Male; Middle Aged; Nitric Oxide; Polyethylene Glycols; Recombinant Proteins; Ribavirin

2009
Asymmetric dimethylarginine in hematological malignancies: a preliminary study.
    Leukemia & lymphoma, 2008, Volume: 49, Issue:12

    Topics: Adult; Aged; Arginine; Biomarkers, Tumor; Case-Control Studies; Female; Hematologic Neoplasms; Humans; Male; Middle Aged; Prognosis; Risk Factors

2008
Role of symmetric dimethylarginine in vascular damage by increasing ROS via store-operated calcium influx in monocytes.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2009, Volume: 24, Issue:5

    Topics: Angiotensin-Converting Enzyme Inhibitors; Anticoagulants; Arginine; Calcium; Calcium Channel Blockers; Calcium Channels; Captopril; Edetic Acid; Enzyme Inhibitors; Humans; Imidazoles; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; Reactive Oxygen Species; Respiratory Burst; Thapsigargin; Vascular Diseases

2009
Transjugular intrahepatic portosystemic shunt-placement increases arginine/asymmetric dimethylarginine ratio in cirrhotic patients.
    World journal of gastroenterology, 2008, Dec-21, Volume: 14, Issue:47

    Topics: Adult; Aged; Aged, 80 and over; Arginine; Female; Follow-Up Studies; Humans; Hypertension, Portal; Liver; Liver Cirrhosis; Male; Middle Aged; Nitric Oxide; Portasystemic Shunt, Transjugular Intrahepatic

2008
Asymmetric and symmetric dimethylarginines are of similar predictive value for cardiovascular risk in the general population.
    Atherosclerosis, 2009, Volume: 205, Issue:1

    Topics: Adult; Aged; Arginine; Cardiovascular Diseases; Cohort Studies; Female; Humans; Male; Mass Spectrometry; Middle Aged; Nitric Oxide; Proportional Hazards Models; Prospective Studies; Risk

2009
ADMA and SDMA levels in healthy men exposed to tobacco smoke.
    Atherosclerosis, 2009, Volume: 205, Issue:2

    Topics: Adolescent; Adult; Arginine; Cerebrovascular Disorders; Coronary Vessels; Humans; Male; Middle Aged; Nitric Oxide Synthase; Regression Analysis; Risk Factors; Smoking; Tobacco Smoke Pollution

2009
Dimethylarginine levels in cerebrospinal fluid of hyperacute ischemic stroke patients are associated with stroke severity.
    Neurochemical research, 2009, Volume: 34, Issue:9

    Topics: Aged; Arginine; Brain Ischemia; Female; Humans; Ischemic Attack, Transient; Male; Middle Aged; Stroke

2009
Endogenous nitric oxide synthase inhibitors in sickle cell disease: abnormal levels and correlations with pulmonary hypertension, desaturation, haemolysis, organ dysfunction and death.
    British journal of haematology, 2009, Volume: 145, Issue:4

    Topics: Anemia, Sickle Cell; Arginine; Case-Control Studies; Citrulline; Follow-Up Studies; Hemolysis; Humans; Hypertension, Pulmonary; Kidney Diseases; Linear Models; Nitric Oxide Synthase; omega-N-Methylarginine; Oxygen; Proportional Hazards Models; Risk; Survival Rate

2009
Methylarginines and mortality in patients with end stage renal disease: a prospective cohort study.
    Atherosclerosis, 2009, Volume: 207, Issue:2

    Topics: Adult; Aged; Arginine; Biomarkers; Female; Hemoglobins; Humans; Kaplan-Meier Estimate; Kidney Failure, Chronic; Male; Methylation; Middle Aged; Predictive Value of Tests; Proportional Hazards Models; Prospective Studies; Renal Dialysis; Risk Assessment; Risk Factors

2009
Targeted metabolomic evaluation of arginine methylation and cardiovascular risks: potential mechanisms beyond nitric oxide synthase inhibition.
    Arteriosclerosis, thrombosis, and vascular biology, 2009, Volume: 29, Issue:9

    Topics: Aged; Arginine; Biomarkers; C-Reactive Protein; Cardiovascular Diseases; Chromatography, High Pressure Liquid; Citrulline; Coronary Artery Disease; Creatinine; Female; Humans; Lysine; Male; Metabolomics; Methylation; Middle Aged; Nitric Oxide Synthase; Odds Ratio; omega-N-Methylarginine; Ornithine; Prognosis; Prospective Studies; Protein Processing, Post-Translational; Risk Assessment; Risk Factors; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Time Factors

2009
Nested case-control study of one-carbon metabolites in mid-pregnancy and risks of cleft lip with and without cleft palate.
    Pediatric research, 2009, Volume: 66, Issue:5

    Topics: Adult; Arginine; Carbon; Case-Control Studies; Cleft Lip; Cleft Palate; Dietary Supplements; Female; Folic Acid; Humans; Maternal Age; Nutritional Sciences; Odds Ratio; Pregnancy; Vitamins

2009
Increased nitric oxide stress is associated with migraine.
    Cephalalgia : an international journal of headache, 2010, Volume: 30, Issue:4

    Topics: Adult; Aged; Amidohydrolases; Arginine; Female; Humans; Male; Migraine with Aura; Nitrates; Nitric Oxide; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Nitrites; Polymorphism, Genetic; Risk Factors; Stress, Physiological

2010
Synergistic effects of asymmetrical dimethyl-L-arginine accumulation and endothelial progenitor cell deficiency on renal function decline during a 2-year follow-up in stable angina.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2010, Volume: 25, Issue:8

    Topics: Adult; Aged; Angina Pectoris; Angioplasty, Balloon, Coronary; Antigens, CD34; Arginine; Biomarkers; Cell Count; Endothelial Cells; Follow-Up Studies; Glomerular Filtration Rate; Humans; Kidney; Leukocytes; Male; Middle Aged; Multivariate Analysis; Stem Cells

2010
Plasma asymmetric dimethylarginine concentrations in sickle cell disease are related to the hemolytic phenotype.
    Blood cells, molecules & diseases, 2010, Apr-15, Volume: 44, Issue:4

    Topics: Adult; Albuminuria; Anemia, Sickle Cell; Arginine; beta-Thalassemia; Cholelithiasis; Female; Hemolysis; Humans; Hypertension, Pulmonary; Leg Ulcer; Male; Middle Aged; Nitric Oxide; Osteonecrosis; Phenotype; Priapism; Retinal Diseases; Sickle Cell Trait; Young Adult

2010
Effects of stent implementation on plasma levels of asymmetric dimethylarginine in patients with or without ST-segment elevation acute myocardial infarction.
    International journal of molecular medicine, 2010, Volume: 25, Issue:4

    Topics: Angioplasty, Balloon, Coronary; Arginine; Case-Control Studies; Coronary Angiography; Female; Humans; Male; Methylation; Middle Aged; Myocardial Infarction; Ornithine; Stents; Ultrasonography

2010
HPLC determination of plasma dimethylarginines: method validation and preliminary clinical application.
    Clinica chimica acta; international journal of clinical chemistry, 2010, Nov-11, Volume: 411, Issue:21-22

    Topics: Adolescent; Adult; Aged; Arginine; Cardiovascular Diseases; Chromatography, High Pressure Liquid; Creatine; Endothelium, Vascular; Female; Glomerular Filtration Rate; Humans; Kidney Function Tests; Male; Middle Aged; Renal Insufficiency, Chronic; Young Adult

2010
Relationships between dimethylarginine and the presence of vertebral fractures in type 2 diabetes mellitus.
    Clinical endocrinology, 2010, Volume: 73, Issue:4

    Topics: Adult; Aged; Arginine; Bone Density; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Female; Humans; Male; Middle Aged; Risk Factors; Spinal Fractures

2010
Plasma levels of asymmetric dimethylarginine in patients with biopsy-proven nonalcoholic fatty liver disease.
    Metabolism: clinical and experimental, 2011, Volume: 60, Issue:6

    Topics: Adult; Arginine; Biopsy; Blood Glucose; Chromatography, High Pressure Liquid; Fatty Liver; Female; Glomerular Filtration Rate; Humans; Insulin Resistance; Liver; Male; Middle Aged

2011
Negative association of L-arginine methylation products with oocyte numbers.
    Human reproduction (Oxford, England), 2010, Volume: 25, Issue:12

    Topics: Adult; Arginine; Female; Fertilization in Vitro; Follicular Fluid; Humans; Methylation; Oocytes; Ovulation Induction

2010
The alteration of asymmetric dimetilarginine (ADMA) levels in cardiac and gastrocnemius muscles following radioactive iodine application in guinea pigs and the effect of L-carnitine on this alteration.
    International journal of radiation biology, 2011, Volume: 87, Issue:1

    Topics: Animals; Arginine; Carnitine; Guinea Pigs; Heart; Homoarginine; Iodine Radioisotopes; Male; Muscle, Skeletal; Myocardium; Radiation-Protective Agents; Thyroid Hormones

2011
Posttranslational arginine methylation of lamin A/C during myoblast fusion.
    Biochimica et biophysica acta, 2011, Volume: 1814, Issue:2

    Topics: Amino Acid Sequence; Animals; Arginine; Blotting, Western; Cell Differentiation; Cells, Cultured; Electrophoresis, Gel, Two-Dimensional; Lamin Type A; Membrane Fusion; Methylation; Molecular Sequence Data; Muscle Development; Muscle Fibers, Skeletal; Myoblasts, Skeletal; Protein Processing, Post-Translational; Protein-Arginine N-Methyltransferases; Rats; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

2011
Dimethylarginines and serotonin in the blood of spontaneously hypertensive rats.
    Bulletin of experimental biology and medicine, 2009, Volume: 148, Issue:6

    Topics: Animals; Arginine; Hydroxyindoleacetic Acid; Nitric Oxide; Rats; Rats, Inbred SHR; Rats, Wistar; Serotonin

2009
Asymmetric dimethylarginine as a risk factor for cardiovascular disease in Japanese patients with type 2 diabetes mellitus.
    Clinical endocrinology, 2011, Volume: 74, Issue:4

    Topics: Aged; Arginine; Asian People; Cardiovascular Diseases; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Female; Humans; Male; Middle Aged; Regression Analysis; Risk Factors

2011
Time course of asymmetric dimethylarginine (ADMA) and oxidative stress in fructose-hypertensive rats: a model related to metabolic syndrome.
    Atherosclerosis, 2011, Volume: 214, Issue:2

    Topics: Animals; Aorta; Arginine; Blood Glucose; Blood Pressure; Body Weight; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fructose; Heart Rate; Hypertension; Male; Metabolic Syndrome; NADPH Oxidases; Nitric Oxide Synthase Type II; Oxidative Stress; Rats; Rats, Sprague-Dawley; Time Factors; Tyrosine; Vasodilation; Vasodilator Agents

2011
Plasma dimethylarginines during the acute inflammatory response.
    European journal of clinical investigation, 2011, Volume: 41, Issue:6

    Topics: Acute-Phase Reaction; Aged; Aged, 80 and over; Arginine; Arthroplasty, Replacement, Knee; Cohort Studies; Dimethylamines; Enzyme Inhibitors; Female; Humans; Inflammation; Knee Joint; Male; Middle Aged; Nitric Oxide; Nitric Oxide Synthase; Postoperative Complications

2011
Asymmetric dimethylarginine as an independent risk marker for mortality in ambulatory patients with peripheral arterial disease.
    Journal of internal medicine, 2011, Volume: 269, Issue:3

    Topics: Aged; Arginine; Biomarkers; Cardiovascular Diseases; Cerebrovascular Disorders; Enzyme Inhibitors; Epidemiologic Methods; Female; Germany; Humans; Male; Nitric Oxide Synthase; Peripheral Arterial Disease; Prognosis

2011
Simultaneous gas chromatography-tandem mass spectrometry quantification of symmetric and asymmetric dimethylarginine in human urine.
    Analytical biochemistry, 2011, Jun-01, Volume: 413, Issue:1

    Topics: Adult; Arginine; Gas Chromatography-Mass Spectrometry; Humans; Stereoisomerism; Tandem Mass Spectrometry

2011
Effects of coronary revascularization with or without cardiopulmonary bypass on plasma levels of asymmetric dimethylarginine.
    Coronary artery disease, 2011, Volume: 22, Issue:4

    Topics: Aged; Arginine; Biomarkers; Cardiopulmonary Bypass; Chromatography, High Pressure Liquid; Coronary Artery Bypass; Coronary Artery Disease; Female; Humans; Male; Middle Aged; Reperfusion Injury; Tandem Mass Spectrometry

2011
Quantitation of L-arginine and asymmetric dimethylarginine in human plasma by LC-selective ion mode-MS for Type 2 diabetes mellitus study.
    Chemical & pharmaceutical bulletin, 2011, Volume: 59, Issue:7

    Topics: Adult; Aged; Arginine; Chromatography, High Pressure Liquid; Diabetes Mellitus, Type 2; Female; Humans; Male; Mass Spectrometry; Middle Aged

2011
The biological effect of pharmacological treatment on dimethylaminohydrolases (DDAH-1) and cationic amino acid transporter-1 (CAT-1) expression in patients with acute congestive heart failure.
    Microvascular research, 2011, Volume: 82, Issue:3

    Topics: Acute Disease; Aged; Amidohydrolases; Arginine; Cardiovascular Agents; Cationic Amino Acid Transporter 1; Chromatography, High Pressure Liquid; Echocardiography, Doppler; Female; Heart Failure; Humans; Italy; Male; Middle Aged; Stroke Volume; Treatment Outcome; Ventricular Function, Left

2011
Asymmetric dimethylarginine predicts appropriate implantable cardioverter-defibrillator intervention in patients with left ventricular dysfunction.
    Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology, 2011, Volume: 13, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Arginine; Biomarkers; Defibrillators, Implantable; Follow-Up Studies; Humans; Male; Middle Aged; Nitric Oxide; Predictive Value of Tests; Prospective Studies; Retrospective Studies; Risk Factors; Tachycardia, Ventricular; Treatment Outcome; Ventricular Dysfunction, Left

2011
Symmetric dimethylarginine as a proinflammatory agent in chronic kidney disease.
    Clinical journal of the American Society of Nephrology : CJASN, 2011, Volume: 6, Issue:10

    Topics: Acetylcysteine; Aged; Aged, 80 and over; Arginine; Belgium; Biomarkers; Case-Control Studies; Cell Line; Chronic Disease; Cross-Sectional Studies; Female; Humans; Inflammation Mediators; Interleukin-6; Kidney Diseases; Linear Models; Male; Middle Aged; Monocytes; NF-kappa B; Predictive Value of Tests; ROC Curve; Tumor Necrosis Factor-alpha

2011
Simultaneous determination of L-arginine, asymmetric dimethylarginine, and symmetric dimethylarginine in the plasma of rodents with LC-MS/MS.
    Arzneimittel-Forschung, 2011, Volume: 61, Issue:6

    Topics: Animals; Arginine; Calibration; Chromatography, High Pressure Liquid; Indicators and Reagents; Male; Mass Spectrometry; Mice; Mice, Inbred ICR; Quality Control; Rats; Rats, Sprague-Dawley; Reference Standards; Reproducibility of Results; Tandem Mass Spectrometry

2011
Increased asymmetric dimethylarginine and enhanced inflammation are associated with impaired vascular reactivity in women with endometriosis.
    Atherosclerosis, 2011, Volume: 219, Issue:2

    Topics: Adult; Arginine; Biomarkers; Brachial Artery; C-Reactive Protein; Case-Control Studies; Endometriosis; Female; Humans; Inflammation Mediators; Interleukin-6; Japan; Least-Squares Analysis; Lipids; Regression Analysis; Serum Amyloid A Protein; Ultrasonography, Doppler; Up-Regulation; Vasodilation

2011
Ethnicity-specific differences in L-arginine status in South African men.
    Journal of human hypertension, 2012, Volume: 26, Issue:12

    Topics: Adult; Aged; Arginine; Black People; Cardiovascular Diseases; Cross-Sectional Studies; Humans; Hypertension; Linear Models; Male; Middle Aged; Multivariate Analysis; Prevalence; Risk Factors; South Africa; White People

2012
The combined ratios of L-arginine and asymmetric and symmetric dimethylarginine as biomarkers in spontaneously hypertensive rats.
    Translational research : the journal of laboratory and clinical medicine, 2012, Volume: 159, Issue:2

    Topics: Amidohydrolases; Animals; Arginine; Biomarkers; Blood Pressure; Hypertension; Male; Models, Animal; Nitric Oxide; Rats; Rats, Inbred SHR; Rats, Inbred WKY

2012
Birth by cesarean section is associated with elevated neonatal plasma levels of dimethylarginines.
    Pediatrics international : official journal of the Japan Pediatric Society, 2012, Volume: 54, Issue:4

    Topics: Arginine; Cesarean Section; Delivery, Obstetric; Female; Humans; Infant, Newborn; Male; Pregnancy

2012
Elevation of serum asymmetrical and symmetrical dimethylarginine in patients with advanced glaucoma.
    Investigative ophthalmology & visual science, 2012, Apr-18, Volume: 53, Issue:4

    Topics: Aged; Arginine; Biomarkers; Female; Follow-Up Studies; Glaucoma; Humans; Intraocular Pressure; Male; Nitric Oxide Synthase; Retrospective Studies; Severity of Illness Index; Tandem Mass Spectrometry

2012
Nitric oxide synthase, ADMA, SDMA, and nitric oxide activity in the paraventricular nucleus throughout the etiology of renal wrap hypertension.
    American journal of physiology. Heart and circulatory physiology, 2012, Jun-01, Volume: 302, Issue:11

    Topics: Animals; Arginine; Blood Pressure; Disease Models, Animal; Enzyme Inhibitors; Hypertension, Renal; Kidney; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Paraventricular Hypothalamic Nucleus; Rats; Rats, Sprague-Dawley

2012
Asymmetric dimethylarginine in adults with cystathionine β-synthase deficiency.
    Atherosclerosis, 2012, Volume: 222, Issue:2

    Topics: Adult; Arginine; Biomarkers; Chromatography, High Pressure Liquid; Endothelium, Vascular; Homocysteine; Homocystinuria; Humans

2012
Asymmetric dimethylarginine (ADMA), symmetric dimethylarginine (SDMA) and L-arginine in patients with arteriogenic and non-arteriogenic erectile dysfunction.
    International journal of andrology, 2012, Volume: 35, Issue:5

    Topics: Adult; Arginine; Erectile Dysfunction; Humans; Impotence, Vasculogenic; Male; Middle Aged

2012
Diagnostic value of plasma asymmetric and symmetric dimethylarginine levels in liver transplant recipients.
    Polskie Archiwum Medycyny Wewnetrznej, 2012, Volume: 122, Issue:7-8

    Topics: Alanine Transaminase; Arginine; Aspartate Aminotransferases; Biomarkers; Cadaver; Fibrosis; Humans; Kidney Transplantation; Predictive Value of Tests; Renal Insufficiency, Chronic

2012
Binding of the heterogeneous ribonucleoprotein K (hnRNP K) to the Epstein-Barr virus nuclear antigen 2 (EBNA2) enhances viral LMP2A expression.
    PloS one, 2012, Volume: 7, Issue:8

    Topics: Antibodies, Monoclonal; Antibody Specificity; Arginine; Cell Line; DNA; Epstein-Barr Virus Infections; Epstein-Barr Virus Nuclear Antigens; Gene Expression Regulation, Viral; Herpesvirus 4, Human; Heterogeneous-Nuclear Ribonucleoprotein K; Humans; Immunoprecipitation; Methylation; Molecular Sequence Data; Multiprotein Complexes; Mutant Proteins; Promoter Regions, Genetic; Protein Binding; Protein Transport; Repetitive Sequences, Amino Acid; snRNP Core Proteins; Transfection; Viral Matrix Proteins; Viral Proteins

2012
Diagnostical significance of dimethylarginine in the development of hepatorenal syndrome in patients with alcoholic liver cirrhosis.
    Vojnosanitetski pregled, 2012, Volume: 69, Issue:8

    Topics: Adult; Aged; Arginine; Biomarkers; Creatinine; Disease Progression; Hepatorenal Syndrome; Humans; Liver Cirrhosis, Alcoholic; Male; Middle Aged

2012
Estradiol, acting through estrogen receptor alpha, restores dimethylarginine dimethylaminohydrolase activity and nitric oxide production in oxLDL-treated human arterial endothelial cells.
    Molecular and cellular endocrinology, 2013, Jan-05, Volume: 365, Issue:1

    Topics: Amidohydrolases; Arginine; Blotting, Western; Cells, Cultured; Endothelium, Vascular; Estradiol; Estrogen Antagonists; Estrogen Receptor alpha; Estrogen Receptor beta; Estrogens, Non-Steroidal; Humans; Isoenzymes; Lipoproteins, LDL; Nitric Oxide; Nitric Oxide Synthase Type III; Protein Stability; Protein-Arginine N-Methyltransferases; Receptors, Estrogen; Receptors, G-Protein-Coupled; Repressor Proteins; Umbilical Arteries

2013
Nitric oxide and carbon monoxide production and metabolism in preeclampsia.
    Reproductive sciences (Thousand Oaks, Calif.), 2013, Volume: 20, Issue:5

    Topics: Adult; Amidohydrolases; Arginine; Biomarkers; Blotting, Western; Carbon Monoxide; Case-Control Studies; Enzyme-Linked Immunosorbent Assay; Female; Heme Oxygenase-1; Humans; Nitric Oxide; Placenta; Pre-Eclampsia; Predictive Value of Tests; Pregnancy; Prospective Studies; Young Adult

2013
INF-β1b therapy modulates L-arginine and nitric oxide metabolism in patients with relapse remittent multiple sclerosis.
    Journal of the neurological sciences, 2012, Dec-15, Volume: 323, Issue:1-2

    Topics: Adult; Arginase; Arginine; Biomarkers; Drug Monitoring; Female; Follow-Up Studies; Humans; Inflammation; Interferon beta-1b; Interferon-beta; Male; Middle Aged; Multiple Sclerosis, Relapsing-Remitting; Nitrates; Nitric Oxide; Nitrites; Nitroso Compounds; Severity of Illness Index; Sulfhydryl Compounds; Tyrosine; Young Adult

2012
Asymmetric and symmetric dimethylarginine and risk of secondary cardiovascular disease events and mortality in patients with stable coronary heart disease: the KAROLA follow-up study.
    Clinical research in cardiology : official journal of the German Cardiac Society, 2013, Volume: 102, Issue:3

    Topics: Aged; Arginine; Biomarkers; Cause of Death; Chromatography, Liquid; Coronary Disease; Female; Follow-Up Studies; Germany; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Multivariate Analysis; Predictive Value of Tests; Prognosis; Proportional Hazards Models; Prospective Studies; Recurrence; Risk Assessment; Risk Factors; Tandem Mass Spectrometry; Time Factors

2013
ADMA, SDMA and L-arginine/ADMA ratio but not DDAH genetic polymorphisms are reliable predictors of diabetic nephropathy progression as identified by competing risk analysis.
    Kidney & blood pressure research, 2012, Volume: 36, Issue:1

    Topics: Adult; Aged; Amidohydrolases; Arginine; Cross-Sectional Studies; Czech Republic; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Disease Progression; Female; Follow-Up Studies; Humans; Male; Methylation; Middle Aged; Multivariate Analysis; Polymorphism, Single Nucleotide; Predictive Value of Tests; Prognosis; Reproducibility of Results; Risk Factors

2012
The L-Arginine-asymmetric dimethylarginine ratio is an independent predictor of mortality in dilated cardiomyopathy.
    Journal of cardiac failure, 2012, Volume: 18, Issue:12

    Topics: Arginine; Biomarkers; Cardiomyopathies; Cardiomyopathy, Dilated; Chromatography, Liquid; Creatinine; Female; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Multivariate Analysis; Myocardial Ischemia; Natriuretic Peptide, Brain; Peptide Fragments; Severity of Illness Index; Tandem Mass Spectrometry

2012
Transsulfuration pathway thiols and methylated arginines: the Hunter Community Study.
    PloS one, 2013, Volume: 8, Issue:1

    Topics: Adrenergic beta-Antagonists; Aged; Aged, 80 and over; Aging; Amidohydrolases; Arginine; Australia; C-Reactive Protein; Cardiovascular Diseases; Cohort Studies; Community Medicine; Cysteine; Dipeptides; Female; Glutathione; Homocysteine; Humans; Male; Middle Aged; Taurine

2013
Heat-assisted extraction for the determination of methylarginines in serum by CE.
    Electrophoresis, 2013, Volume: 34, Issue:11

    Topics: Arginine; Cardiovascular Diseases; Electrophoresis, Capillary; Hot Temperature; Humans; omega-N-Methylarginine; Solid Phase Extraction

2013
Effects of salvianolic acid A on plasma and tissue dimethylarginine levels in a rat model of myocardial infarction.
    Journal of cardiovascular pharmacology, 2013, Volume: 61, Issue:6

    Topics: Amidohydrolases; Animals; Arginine; Caffeic Acids; Chromatography, High Pressure Liquid; Creatinine; Disease Models, Animal; Heart Ventricles; Kidney; Lactates; Liver; Male; Myocardial Infarction; Proton Pump Inhibitors; Rats; Rats, Sprague-Dawley; Tandem Mass Spectrometry

2013
The methylarginines NMMA, ADMA, and SDMA are ubiquitous constituents of the main vegetables of human nutrition.
    Nitric oxide : biology and chemistry, 2013, Apr-01, Volume: 30

    Topics: Arginine; Chromatography, High Pressure Liquid; Chromatography, Reverse-Phase; Vegetables

2013
Influence of ezetimibe on ADMA-DDAH-NO pathway in rat liver subjected to partial ischemia followed by global reperfusion.
    Pharmacological reports : PR, 2013, Volume: 65, Issue:1

    Topics: Amidohydrolases; Animals; Anticholesteremic Agents; Arginine; Azetidines; Ezetimibe; Liver; Male; Nitric Oxide; Nitric Oxide Synthase Type III; Rats; Rats, Wistar; Real-Time Polymerase Chain Reaction; Reperfusion Injury; RNA, Messenger; Time Factors

2013
Increased symmetrical dimethylarginine in ischemic acute kidney injury as a causative factor of renal L-arginine deficiency.
    Translational research : the journal of laboratory and clinical medicine, 2013, Volume: 162, Issue:2

    Topics: Acute Kidney Injury; Amidohydrolases; Animals; Arginine; Blotting, Western; Chromatography, High Pressure Liquid; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Female; Intracellular Signaling Peptides and Proteins; Kidney; Kidney Function Tests; Protein-Arginine N-Methyltransferases; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Reperfusion Injury; Tandem Mass Spectrometry

2013
Plasma concentrations of arginine and asymmetric dimethylarginine do not reflect their intracellular concentrations in peripheral blood mononuclear cells.
    Metabolism: clinical and experimental, 2013, Volume: 62, Issue:10

    Topics: Arginine; Biomarkers; Homoarginine; Humans; Leukocytes, Mononuclear; Nitric Oxide

2013
Serum methylarginines and incident depression in a cohort of older adults.
    Journal of affective disorders, 2013, Volume: 151, Issue:2

    Topics: Aged; Aged, 80 and over; Arginine; Depression; Female; Follow-Up Studies; Humans; Incidence; Male; Middle Aged; New South Wales; Nitric Oxide Synthase

2013
Effects of acute and chronic stress on the L-arginine nitric oxide pathway in black and white South Africans: the sympathetic activity and ambulatory blood pressure in Africans study.
    Psychosomatic medicine, 2013, Volume: 75, Issue:8

    Topics: Acute Disease; Adult; Arginine; Black People; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Cardiovascular Diseases; Chronic Disease; Cold Temperature; Cross-Sectional Studies; Disease Susceptibility; Female; Hemodynamics; Humans; Male; Middle Aged; Motor Activity; Nitric Oxide; Pressure; Rest; South Africa; Stress, Psychological; Stroop Test; White People

2013
Symmetrical dimethylarginine predicts mortality in the general population: observations from the Dallas heart study.
    Arteriosclerosis, thrombosis, and vascular biology, 2013, Volume: 33, Issue:11

    Topics: Adult; Aged; Arginine; Cardiovascular Diseases; Female; Follow-Up Studies; Humans; Male; Middle Aged; Predictive Value of Tests; Prognosis; Proportional Hazards Models; Risk Factors; Texas

2013
Gender differences in oxidative and nitrosative stress parameters in kidney transplant patients on tacrolimus-based immunosuppression.
    International urology and nephrology, 2014, Volume: 46, Issue:6

    Topics: Adult; Advanced Oxidation Protein Products; Arginine; Catalase; Female; Healthy Volunteers; Humans; Immunosuppressive Agents; Kidney Transplantation; Male; Middle Aged; Mycophenolic Acid; Nitrates; Nitrites; Oxidative Stress; Prednisone; Sex Factors; Sulfhydryl Compounds; Tacrolimus; Thiobarbituric Acid Reactive Substances

2014
Memory impairment is associated with serum methylarginines in older adults.
    Current Alzheimer research, 2014, Volume: 11, Issue:1

    Topics: Aged; Aged, 80 and over; Arginine; Atrial Fibrillation; Cohort Studies; Diabetes Mellitus; Educational Status; Female; Humans; Logistic Models; Male; Memory Disorders; Middle Aged; Multivariate Analysis; Neuropsychological Tests; Odds Ratio; Severity of Illness Index

2014
Genetic and environmental determinants of dimethylarginines and association with cardiovascular disease in patients with type 2 diabetes.
    Diabetes care, 2014, Volume: 37, Issue:3

    Topics: Aged; Arginine; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Environment; Female; Genotype; Humans; Intermittent Claudication; Male; Middle Aged; Polymorphism, Single Nucleotide; Risk Factors

2014
L-arginine, asymmetric dimethylarginine, and symmetric dimethylarginine in plasma and synovial fluid of patients with knee osteoarthritis.
    Medical science monitor : international medical journal of experimental and clinical research, 2013, Nov-26, Volume: 19

    Topics: Arginine; Case-Control Studies; Humans; Nitric Oxide; Osteoarthritis, Knee; Signal Transduction; Synovial Fluid; Thiobarbituric Acid Reactive Substances

2013
Asymmetric dimethylarginine responses during interferon-α-induced depression in patients with chronic hepatitis C infection.
    Psychosomatic medicine, 2014, Volume: 76, Issue:3

    Topics: Adult; Analysis of Variance; Antiviral Agents; Arginine; Cardiovascular Diseases; Chromatography, Liquid; Depression; Depressive Disorder; Drug Therapy, Combination; Female; Hepatitis C, Chronic; Humans; Interferon-alpha; Male; Nitric Oxide Synthase; Prospective Studies; Psychiatric Status Rating Scales; Regression Analysis; Ribavirin; Risk Factors; Time Factors

2014
Structural determinants for the strict monomethylation activity by trypanosoma brucei protein arginine methyltransferase 7.
    Structure (London, England : 1993), 2014, May-06, Volume: 22, Issue:5

    Topics: Amino Acid Sequence; Arginine; Catalytic Domain; Crystallography, X-Ray; Guanidine; Histones; Methylation; Models, Molecular; Molecular Sequence Data; Protein Multimerization; Protein-Arginine N-Methyltransferases; Protozoan Proteins; S-Adenosylhomocysteine; S-Adenosylmethionine; Trypanosoma brucei brucei

2014
ADMA/SDMA in elderly subjects with asymptomatic carotid atherosclerosis: values and site-specific association.
    International journal of molecular sciences, 2014, Apr-15, Volume: 15, Issue:4

    Topics: Aged; Aged, 80 and over; Arginine; C-Reactive Protein; Carotid Arteries; Carotid Artery Diseases; Carotid Intima-Media Thickness; Cholesterol; Cholesterol, LDL; Female; Humans; Male; Middle Aged; Triglycerides

2014
Incidence of all-cause and cardiovascular mortality predicted by symmetric dimethylarginine in the population-based study of health in pomerania.
    PloS one, 2014, Volume: 9, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Arginine; Cardiovascular Diseases; Female; Humans; Incidence; Male; Middle Aged; Young Adult

2014
Asymmetric and symmetric dimethylarginine are associated with coronary artery lesions in Kawasaki disease.
    The Journal of pediatrics, 2014, Volume: 165, Issue:2

    Topics: Arginine; Biomarkers; Child, Preschool; Coronary Artery Disease; Coronary Vessels; Female; Humans; Immunoglobulins, Intravenous; Infant; Male; Mucocutaneous Lymph Node Syndrome

2014
Serum reference intervals of homoarginine, ADMA, and SDMA in the study of health in Pomerania.
    Clinical chemistry and laboratory medicine, 2014, Volume: 52, Issue:12

    Topics: Adult; Aged; Arginine; Biomarkers; Body Mass Index; Cardiovascular Diseases; Chromatography, High Pressure Liquid; Female; Homoarginine; Humans; Male; Middle Aged; Reference Values; Renal Insufficiency, Chronic; Risk Factors; Tandem Mass Spectrometry

2014
Time course of asymmetric dimethylarginine and symmetric dimethylarginine levels after successful renal transplantation.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2014, Volume: 29, Issue:10

    Topics: Adult; Aged; Arginine; Biomarkers; Case-Control Studies; Chromatography, High Pressure Liquid; Female; Glomerular Filtration Rate; Humans; Kidney Transplantation; Male; Middle Aged; Postoperative Complications; Prospective Studies; Renal Insufficiency, Chronic; Risk Factors; Young Adult

2014
Association between brachial-ankle pulse wave velocity and the ratio of l-arginine to asymmetric dimethylarginine in patients undergoing coronary angiography.
    Journal of cardiology, 2015, Volume: 65, Issue:4

    Topics: Aged; Ankle Brachial Index; Arginine; Blood Pressure; Coronary Angiography; Coronary Artery Disease; Cross-Sectional Studies; Female; Heart Rate; Hematocrit; Hemoglobins; Humans; Kidney; Male; Middle Aged; Natriuretic Peptide, Brain; Pulse Wave Analysis; Vascular Stiffness

2015
Monocyte activation, but not microbial translocation, is independently associated with markers of endovascular dysfunction in HIV-infected patients receiving cART.
    Journal of acquired immune deficiency syndromes (1999), 2014, Dec-01, Volume: 67, Issue:4

    Topics: Adult; Aged; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Arginine; Bacterial Translocation; Biomarkers; Cardiovascular Diseases; Female; Fibrin Fibrinogen Degradation Products; HIV Infections; Humans; Lipopolysaccharide Receptors; Lipopolysaccharides; Male; Middle Aged; Monocytes

2014
Genome-wide association study of L-arginine and dimethylarginines reveals novel metabolic pathway for symmetric dimethylarginine.
    Circulation. Cardiovascular genetics, 2014, Volume: 7, Issue:6

    Topics: Adult; Aged; Amidohydrolases; Arginine; Binding Sites; Cohort Studies; Female; Genetic Loci; Genome-Wide Association Study; Genotype; HEK293 Cells; Humans; Male; Mediator Complex; Middle Aged; Polymorphism, Single Nucleotide; Protein Structure, Tertiary; Risk Factors; Stroke; Substrate Specificity; Transaminases

2014
Soluble CD14 is associated with markers of vascular dysfunction in bariatric surgery patients.
    Metabolic syndrome and related disorders, 2015, Volume: 13, Issue:3

    Topics: Adipose Tissue; Adult; Age Factors; Arginine; Bariatric Surgery; Biomarkers; Female; Humans; Lipopolysaccharide Receptors; Lipopolysaccharides; Male; Middle Aged; Monocytes; Obesity; Prospective Studies; Risk Factors; Sex Factors; Vascular Diseases

2015
The role of asymmetric and symmetric dimethylarginine in acute deep vein thrombosis.
    Annals of vascular surgery, 2015, Volume: 29, Issue:5

    Topics: Acute Disease; Adult; Arginine; Biomarkers; Case-Control Studies; Chromatography, High Pressure Liquid; Female; Humans; Male; Middle Aged; Treatment Outcome; Venous Thrombosis

2015
Nitric oxide dysregulation in patients with heart failure: the association of depressive symptoms with L-arginine, asymmetric dimethylarginine, symmetric dimethylarginine, and isoprostane.
    Psychosomatic medicine, 2015, Volume: 77, Issue:3

    Topics: Aged; Arginine; Depression; Female; Heart Failure; Humans; Isoprostanes; Linear Models; Male; Middle Aged; Nitric Oxide; Oxidative Stress

2015
Plasma asymmetric and symmetric dimethylarginine in a rat model of endothelial dysfunction induced by acute hyperhomocysteinemia.
    Amino acids, 2015, Volume: 47, Issue:9

    Topics: Amidohydrolases; Animals; Arginine; Cathepsin D; Disease Models, Animal; Endothelium, Vascular; Gene Expression Regulation; Hyperhomocysteinemia; Liver; Male; Methionine; Rats; Rats, Wistar; Ubiquitin

2015
Physical exercise reduces synthesis of ADMA, SDMA, and L-Arg.
    Frontiers in bioscience (Elite edition), 2015, 06-01, Volume: 7, Issue:3

    Topics: Arginine; Biomarkers; Coronary Artery Disease; Exercise; Female; Humans; Male; Middle Aged; Nitric Oxide

2015
Dimethylarginines as biomarkers for the kidney transplant management in methylmalonic aciduria.
    Nephrology (Carlton, Vic.), 2015, Volume: 20, Issue:8

    Topics: Adult; Allografts; Amino Acid Metabolism, Inborn Errors; Arginine; Biomarkers; Cause of Death; Disease Progression; Fatal Outcome; Humans; Immunosuppressive Agents; Kidney Failure, Chronic; Kidney Transplantation; Living Donors; Male; Pancreatitis; Predictive Value of Tests; Risk Factors; Time Factors; Treatment Outcome

2015
Asymmetric dimethylarginine in experimental breast cancer; action of Vitamin C and E.
    JPMA. The Journal of the Pakistan Medical Association, 2015, Volume: 65, Issue:8

    Topics: Animals; Antioxidants; Arginase; Arginine; Ascorbic Acid; Female; Mammary Neoplasms, Experimental; Mice; Nitric Oxide; Nitric Oxide Synthase; Vitamin E

2015
The effect of nephropathy on plasma sphingosine 1-phosphate concentrations in patients with type 2 diabetes.
    Clinical biochemistry, 2015, Volume: 48, Issue:18

    Topics: Albuminuria; Apolipoproteins; Apolipoproteins M; Arginine; Biological Transport; Cholesterol, HDL; Cholesterol, LDL; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Female; Humans; Lipocalins; Lysophospholipids; Male; Middle Aged; Sphingosine; Triglycerides

2015
Asymmetric dimethylarginine is transported by the mitochondrial carrier SLC25A2.
    Amino acids, 2016, Volume: 48, Issue:2

    Topics: Amino Acid Transport Systems, Basic; Arginine; Biological Transport; Carrier Proteins; Cell Line, Tumor; Humans; Kidney Tubules, Proximal; Mitochondria; Mitochondrial Membranes; Transaminases

2016
ADMA, subclinical changes and atrial fibrillation in the general population.
    International journal of cardiology, 2016, Jan-15, Volume: 203

    Topics: Adult; Aged; Arginine; Atrial Fibrillation; Biomarkers; Chromatography, Liquid; Echocardiography; Electrocardiography; Female; Germany; Humans; Male; Middle Aged; Morbidity; omega-N-Methylarginine; Oxidative Stress; Population Surveillance; Tandem Mass Spectrometry

2016
Nitric Oxide-Related Biological Pathways in Patients with Major Depression.
    PloS one, 2015, Volume: 10, Issue:11

    Topics: Adult; Arginase; Arginine; Biological Availability; Case-Control Studies; Demography; Depressive Disorder, Major; Female; Humans; Male; Middle Aged; Nitric Oxide; Psychometrics; Signal Transduction

2015
Methylarginines in Mice with Experimental Atherosclerosis.
    Bulletin of experimental biology and medicine, 2015, Volume: 160, Issue:1

    Topics: Animals; Arginine; Atherosclerosis; Cholesterol; Endothelium, Vascular; Male; Mice; Mice, Inbred CBA; Nitric Oxide Synthase; omega-N-Methylarginine; Poloxamer; Triglycerides

2015
Acetylation of asymmetric and symmetric dimethylarginine: an undercharacterized pathway of metabolism of endogenous methylarginines.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2016, Volume: 31, Issue:1

    Topics: Acetylation; Animals; Arginine; Chromatography, Liquid; Kidney; Male; Metabolic Networks and Pathways; Mice; Mice, Inbred C57BL; Nephrectomy; Organ Specificity; Protein Processing, Post-Translational

2016
L-Arginine Derivatives Are Associated with the Hyperthyroid State in the General Population.
    Thyroid : official journal of the American Thyroid Association, 2016, Volume: 26, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Arginine; Atherosclerosis; Cross-Sectional Studies; Female; Germany; Humans; Hyperthyroidism; Male; Middle Aged; Regression Analysis; Thyroid Function Tests; Thyroid Gland; Thyrotropin; Thyroxine; Triiodothyronine; Young Adult

2016
Changes in Biliary Levels of Arginine and its Methylated Derivatives after Hepatic Ischaemia/Reperfusion.
    Basic & clinical pharmacology & toxicology, 2016, Volume: 119, Issue:1

    Topics: Alanine Transaminase; Alkaline Phosphatase; Amidohydrolases; Amino Acid Transport Systems, Basic; Animals; Arginine; Aspartate Aminotransferases; Bile; Citrulline; Liver; Liver Diseases; Male; Nitric Oxide; Rats; Rats, Wistar; Reperfusion Injury; RNA, Messenger

2016
Whole-body synthesis of L-homoarginine in pigs and rats supplemented with L-arginine.
    Amino acids, 2016, Volume: 48, Issue:4

    Topics: Animal Feed; Animals; Arginine; Body Weight; Creatinine; Dietary Supplements; Female; Glycine max; Homoarginine; Male; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; Swine; Zea mays

2016
Assessment of heat shock proteins and endothelial dysfunction in acute pulmonary embolism.
    Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, 2016, Volume: 27, Issue:4

    Topics: Acute Disease; Adult; Aged; Arginine; Biomarkers; Case-Control Studies; Endothelium, Vascular; Female; Gene Expression; Heat-Shock Proteins; HSP27 Heat-Shock Proteins; HSP70 Heat-Shock Proteins; HSP90 Heat-Shock Proteins; Humans; Male; Middle Aged; Molecular Chaperones; Oxidative Stress; Oxygen; Pulmonary Artery; Pulmonary Embolism

2016
The separation and analysis of symmetric and asymmetric dimethylarginine and other hydrophilic isobaric compounds using aqueous normal phase chromatography.
    Journal of chromatography. A, 2016, Apr-08, Volume: 1441

    Topics: Arginine; Case-Control Studies; Chromatography, Liquid; Humans; Hydrophobic and Hydrophilic Interactions; Silicates; Tuberculosis, Pulmonary; Water

2016
Detrimental effects of a bout of physical exercise on circulating endogenous inhibitors of endothelial function in patients with coronary artery disease.
    Journal of cardiovascular medicine (Hagerstown, Md.), 2017, Volume: 18, Issue:8

    Topics: Adult; Aged; Arginine; Biomarkers; Case-Control Studies; Coronary Artery Disease; Echocardiography; Exercise; Exercise Test; Female; Humans; Male; Middle Aged; Nitric Oxide Synthase; Risk Factors; Young Adult

2017
Determination of Asymmetric and Symmetric Dimethylarginine in Serum from Patients with Chronic Kidney Disease: UPLC-MS/MS versus ELISA.
    Toxins, 2016, 05-13, Volume: 8, Issue:5

    Topics: Arginine; Chromatography, High Pressure Liquid; Enzyme-Linked Immunosorbent Assay; Humans; Renal Insufficiency, Chronic; Tandem Mass Spectrometry

2016
High Levels of Methylarginines Were Associated With Increased Mortality in Patients With Severe Sepsis.
    Shock (Augusta, Ga.), 2016, Volume: 46, Issue:4

    Topics: Aged; Arginine; Female; Humans; Male; Middle Aged; Nitric Oxide; Proportional Hazards Models; Sepsis; Shock, Septic

2016
Asymmetric dimethylarginine, related arginine derivatives, and incident atrial fibrillation.
    American heart journal, 2016, Volume: 176

    Topics: Aged; Arginine; Atrial Fibrillation; Biomarkers; Cohort Studies; Female; Humans; Incidence; Male; Middle Aged; Oxidative Stress; Proportional Hazards Models; Reproducibility of Results; Statistics as Topic

2016
Endothelin 1, ADMA and SDMA in pregnancies with obstetric and thrombotic antiphospholipid syndrome.
    Journal of reproductive immunology, 2016, Volume: 116

    Topics: Adult; Antiphospholipid Syndrome; Arginine; Chronic Disease; Endothelin-1; Endothelium, Vascular; Female; Humans; Hypertension; Pre-Eclampsia; Pregnancy; Prognosis; Thrombosis; Young Adult

2016
Arginines Plasma Concentration and Oxidative Stress in Mild to Moderate COPD.
    PloS one, 2016, Volume: 11, Issue:8

    Topics: Age Factors; Aged; Aged, 80 and over; Arginine; Aryldialkylphosphatase; Biomarkers; Case-Control Studies; Female; Forced Expiratory Volume; Humans; Linear Models; Male; Middle Aged; Nitric Oxide; Oxidative Stress; Pulmonary Disease, Chronic Obstructive; Severity of Illness Index; Sex Factors; Taurine

2016
Diabetes-linked transcription factor HNF4α regulates metabolism of endogenous methylarginines and β-aminoisobutyric acid by controlling expression of alanine-glyoxylate aminotransferase 2.
    Scientific reports, 2016, 10-18, Volume: 6

    Topics: Aminoisobutyric Acids; Animals; Arginine; Cardiovascular Diseases; Cell Line; Diabetes Mellitus, Type 2; Gene Expression Regulation; Hepatocyte Nuclear Factor 4; Humans; Liver; Mice; Mice, Inbred C57BL; Mice, Knockout; Polymorphism, Single Nucleotide; Promoter Regions, Genetic; Risk; RNA, Small Interfering; Transaminases

2016
Higher serum asymmetric dimethylarginine is related to higher risk of heart failure in the EPIC-Potsdam study.
    Amino acids, 2017, Volume: 49, Issue:1

    Topics: Adult; Aged; Arginine; Biomarkers; Feeding Behavior; Female; Germany; Heart Failure; Humans; Male; Middle Aged; Myocardial Infarction; Prognosis; Proportional Hazards Models; Prospective Studies; Risk

2017
l-Arginine Pathway Metabolites Predict Need for Intra-operative Shunt During Carotid Endarterectomy.
    European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery, 2016, Volume: 52, Issue:6

    Topics: Aged; Anaerobiosis; Area Under Curve; Arginine; Biomarkers; Blood Gas Analysis; Blood-Brain Barrier; Capillary Permeability; Carotid Stenosis; Cerebrovascular Circulation; Constriction; Endarterectomy, Carotid; Female; Humans; Jugular Veins; Lactic Acid; Male; Middle Aged; Pilot Projects; Predictive Value of Tests; Prospective Studies; Radial Artery; Reproducibility of Results; Risk Factors; ROC Curve; S100 Calcium Binding Protein beta Subunit; Time Factors; Treatment Outcome

2016
Effect of l-arginine, asymmetric dimethylarginine, and symmetric dimethylarginine on ischemic heart disease risk: A Mendelian randomization study.
    American heart journal, 2016, Volume: 182

    Topics: Arginine; Female; Genome-Wide Association Study; Humans; Male; Mediator Complex; Mendelian Randomization Analysis; Myocardial Infarction; Polymorphism, Single Nucleotide; Transaminases

2016
Admission levels of asymmetric and symmetric dimethylarginine predict long-term outcome in patients with community-acquired pneumonia.
    Respiratory research, 2017, 01-23, Volume: 18, Issue:1

    Topics: Adult; Aged; Arginine; Biomarkers; Community-Acquired Infections; Female; Humans; Longitudinal Studies; Male; Middle Aged; Patient Admission; Pneumonia; Prevalence; Proportional Hazards Models; Risk Assessment; Risk Factors; Survival Analysis; Switzerland

2017
Investigation of Asymmetric and Symmetric Dimethylarginine Levels after Iloprost Treatment in Patients with Buerger's Disease.
    European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery, 2017, Volume: 53, Issue:3

    Topics: Adult; Aged; Arginine; Biomarkers; Female; Humans; Iloprost; Infusions, Intravenous; Male; Middle Aged; Thromboangiitis Obliterans; Time Factors; Treatment Outcome; Vasodilator Agents

2017
DdaR (PA1196) Regulates Expression of Dimethylarginine Dimethylaminohydrolase for the Metabolism of Methylarginines in Pseudomonas aeruginosa PAO1.
    Journal of bacteriology, 2017, 04-15, Volume: 199, Issue:8

    Topics: Amidohydrolases; Arginine; Bacterial Proteins; Gene Expression Regulation, Bacterial; Gene Expression Regulation, Enzymologic; omega-N-Methylarginine; Pseudomonas aeruginosa; RNA Polymerase Sigma 54

2017
Metabolic profiling of presymptomatic Huntington's disease sheep reveals novel biomarkers.
    Scientific reports, 2017, 02-22, Volume: 7

    Topics: Amino Acids, Branched-Chain; Animals; Animals, Genetically Modified; Area Under Curve; Arginine; Biomarkers; Citrulline; Genotype; Huntington Disease; Logistic Models; Metabolomics; ROC Curve; Sheep

2017
Plasma Arginine/Asymmetric Dimethylarginine Ratio and Incidence of Cardiovascular Events: A Case-Cohort Study.
    The Journal of clinical endocrinology and metabolism, 2017, 06-01, Volume: 102, Issue:6

    Topics: Aged; Arginine; Cardiovascular Diseases; Case-Control Studies; Chromatography, Liquid; Citrulline; Cohort Studies; Female; Humans; Incidence; Male; Middle Aged; Multivariate Analysis; Myocardial Infarction; omega-N-Methylarginine; Ornithine; Proportional Hazards Models; Prospective Studies; Risk Factors; Stroke; Tandem Mass Spectrometry

2017
Effect of arginine:lysine and glycine:methionine intake ratios on dyslipidemia and selected biomarkers implicated in cardiovascular disease: A study with hypercholesterolemic rats.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2017, Volume: 91

    Topics: Administration, Oral; Amino Acids; Animals; Arginine; Biomarkers; Body Weight; Cardiovascular Diseases; Dyslipidemias; Glycine; Homocysteine; Hypercholesterolemia; Lipids; Liver; Lysine; Male; Methionine; Nitric Oxide; Organ Size; Rats, Wistar

2017
Renalase Assessment With Regard to Kidney Function, Lipid Disturbances, and Endothelial Dysfunction Parameters in Stable Renal Transplant Recipients.
    Progress in transplantation (Aliso Viejo, Calif.), 2017, Volume: 27, Issue:2

    Topics: Adult; Antihypertensive Agents; Arginine; C-Reactive Protein; Case-Control Studies; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Creatinine; Cross-Sectional Studies; Endothelium, Vascular; Female; Glomerular Filtration Rate; Hemoglobins; Humans; Hypertension; Intercellular Adhesion Molecule-1; Kidney Transplantation; Male; Middle Aged; Monoamine Oxidase; Renal Insufficiency, Chronic; Severity of Illness Index; Vascular Cell Adhesion Molecule-1

2017
Physical activity - related changes in ADMA and vWF levels in patients with type 2 diabetes: A preliminary study.
    Advances in clinical and experimental medicine : official organ Wroclaw Medical University, 2017, Volume: 26, Issue:4

    Topics: Adult; Arginine; Cholesterol, HDL; Diabetes Mellitus, Type 2; Exercise; Female; Humans; Male; Middle Aged; von Willebrand Factor

2017
Cardiomyocyte dimethylarginine dimethylaminohydrolase-1 (DDAH1) plays an important role in attenuating ventricular hypertrophy and dysfunction.
    Basic research in cardiology, 2017, 08-17, Volume: 112, Issue:5

    Topics: Amidohydrolases; Animals; Arginine; Atrial Natriuretic Factor; Disease Models, Animal; Fibrosis; Genetic Predisposition to Disease; Hypertrophy, Left Ventricular; Male; Mice, Knockout; Myocytes, Cardiac; Nitric Oxide; Phenotype; Signal Transduction; Tyrosine; Ventricular Dysfunction, Left; Ventricular Function, Left; Ventricular Remodeling

2017
Asymmetric dimethylarginine and symmetric dimethylarginine prospectively relates to carotid wall thickening in black men: the SABPA study.
    Amino acids, 2017, Volume: 49, Issue:11

    Topics: Adult; Arginine; Black People; Cardiovascular Diseases; Carotid Intima-Media Thickness; Follow-Up Studies; Humans; Male; Middle Aged; Prospective Studies; Regression Analysis; South America; White People

2017
Systemic vascular resistance and endogenous inhibitors of nitric oxide synthesis in early- compared to late-onset preeclampsia: preliminary findings.
    Hypertension in pregnancy, 2017, Volume: 36, Issue:3

    Topics: Adult; Arginine; Case-Control Studies; Female; Humans; Pre-Eclampsia; Pregnancy; Vascular Resistance; Young Adult

2017
Asymmetric Dimethylarginine Predicts Long-Term Outcome in Patients with Acute Exacerbation of Chronic Obstructive Pulmonary Disease.
    Lung, 2017, Volume: 195, Issue:6

    Topics: Aged; Aged, 80 and over; Arginine; Biomarkers; Disease Progression; Female; Humans; Male; Middle Aged; Prognosis; Proportional Hazards Models; Pulmonary Disease, Chronic Obstructive; Risk Factors; Severity of Illness Index; Survival Rate; Switzerland; Time Factors

2017
Spontaneous variability of pre-dialysis concentrations of uremic toxins over time in stable hemodialysis patients.
    PloS one, 2017, Volume: 12, Issue:10

    Topics: Aged; Aged, 80 and over; Analysis of Variance; Arginine; beta 2-Microglobulin; Creatinine; Female; Hemodialysis Solutions; Hippurates; Humans; Indican; Male; Middle Aged; Observer Variation; Phosphorus; Renal Dialysis; Renal Insufficiency, Chronic; Toxins, Biological; Urea; Uric Acid

2017
Opposing effects of rheumatoid arthritis and low dose prednisolone on arginine metabolomics.
    Atherosclerosis, 2017, Volume: 266

    Topics: Administration, Oral; Aged; Arginine; Arthritis, Rheumatoid; Biomarkers; Case-Control Studies; Chromatography, Liquid; Drug Administration Schedule; Endothelium, Vascular; Female; Glucocorticoids; Homoarginine; Humans; Male; Mass Spectrometry; Metabolomics; Middle Aged; Prednisolone; Time Factors; Treatment Outcome

2017
Symmetric dimethylarginine (SDMA) outperforms asymmetric dimethylarginine (ADMA) and other methylarginines as predictor of renal and cardiovascular outcome in non-dialysis chronic kidney disease.
    Clinical research in cardiology : official journal of the German Cardiac Society, 2018, Volume: 107, Issue:3

    Topics: Aged; Arginine; Biomarkers; Cardiovascular Diseases; Chromatography, Liquid; Disease Progression; Female; Germany; Humans; Incidence; Male; Middle Aged; omega-N-Methylarginine; Prognosis; Renal Dialysis; Renal Insufficiency, Chronic; Risk Assessment; Risk Factors

2018
Inverse correlation between maternal plasma asymmetric dimethylarginine (ADMA) and birthweight percentile in women with impaired placental perfusion: circulating ADMA as an NO-independent indicator of fetal growth restriction?
    Amino acids, 2018, Volume: 50, Issue:2

    Topics: Adult; Arginine; Biomarkers; Birth Weight; Female; Fetal Growth Retardation; Fetus; Gestational Age; Humans; Infant, Newborn; Male; Nitrates; Nitric Oxide; Nitrites; Placenta; Pre-Eclampsia; Pregnancy; Pregnancy Outcome

2018
Amniotic Fluid Arginine from Gestational Weeks 13 to 15 Is a Predictor of Birth Weight, Length, and Head Circumference.
    Nutrients, 2017, Dec-14, Volume: 9, Issue:12

    Topics: Adult; Amniotic Fluid; Arginine; Birth Weight; Dietary Supplements; Female; Fetal Growth Retardation; Humans; Infant; Male; Middle Aged; Nitric Oxide; Pregnancy; Pregnancy Trimesters; Young Adult

2017
Global arginine bioavailability ratio is decreased in patients with major depressive disorder.
    Journal of affective disorders, 2018, 03-15, Volume: 229

    Topics: Adult; Aged; Arginine; Biological Availability; Citrulline; Depressive Disorder, Major; Female; Humans; Male; Middle Aged; Nitric Oxide; Ornithine; Oxidative Stress; Surveys and Questionnaires; Young Adult

2018
Malaria in pregnancy alters l-arginine bioavailability and placental vascular development.
    Science translational medicine, 2018, 03-07, Volume: 10, Issue:431

    Topics: Animals; Arginine; Female; Humans; Malaria; Mice; Nitric Oxide; Placenta; Pregnancy; Pregnancy Outcome; Prospective Studies

2018
Serum concentrations of asymmetric and symmetric dimethylarginine are associated with mortality in acute heart failure patients.
    International journal of cardiology, 2018, 06-15, Volume: 261

    Topics: Acute Disease; Aged; Aged, 80 and over; Arginine; Biomarkers; Cohort Studies; Female; Heart Failure; Humans; Male; Mortality; Stroke Volume

2018
Asymmetric and Symmetric Dimethylarginines are Markers of Delayed Cerebral Ischemia and Neurological Outcome in Patients with Subarachnoid Hemorrhage.
    Neurocritical care, 2018, Volume: 29, Issue:1

    Topics: Adult; Aged; Arginine; Biomarkers; Brain Ischemia; Cerebral Angiography; Female; Humans; Incidence; Male; Middle Aged; Outcome Assessment, Health Care; Subarachnoid Hemorrhage

2018
Alterations in plasma L-arginine and methylarginines in heart failure and after heart transplantation.
    Scandinavian cardiovascular journal : SCJ, 2018, Volume: 52, Issue:4

    Topics: Arginine; Biomarkers; Citrulline; Endothelium, Vascular; Female; Heart Failure; Heart Transplantation; Hemodynamics; Humans; Male; Middle Aged; Nitric Oxide; Ornithine; Prospective Studies; Time Factors; Treatment Outcome

2018
Asymmetric and symmetric dimethylarginines and mortality in patients with hematological malignancies-A prospective study.
    PloS one, 2018, Volume: 13, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Arginine; Biomarkers, Tumor; Case-Control Studies; Female; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Myeloid, Acute; Lymphoma, Non-Hodgkin; Male; Middle Aged; Prognosis; Prospective Studies; Survival Rate; Young Adult

2018
Elevated levels of plasma symmetric dimethylarginine and increased arginase activity as potential indicators of cardiovascular comorbidity in rheumatoid arthritis.
    Arthritis research & therapy, 2018, 06-08, Volume: 20, Issue:1

    Topics: Aged; Arginase; Arginine; Arthritis, Rheumatoid; Biomarkers; Cardiovascular Diseases; Comorbidity; Female; Humans; Hyperlipidemias; Hypertension; Male; Middle Aged; Prevalence; Risk Factors; United States

2018
Plasma Homoarginine Concentrations According to Use of Hormonal Contraception.
    Scientific reports, 2018, 08-15, Volume: 8, Issue:1

    Topics: Adolescent; Adult; Arginine; Chromatography, Liquid; Contraception; Contraceptives, Oral, Hormonal; Estrogens; Female; Homoarginine; Humans; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Progestins; Tandem Mass Spectrometry; Young Adult

2018
Changes in arginine are inversely associated with type 2 diabetes: A case-cohort study in the PREDIMED trial.
    Diabetes, obesity & metabolism, 2019, Volume: 21, Issue:2

    Topics: Aged; Aged, 80 and over; Arginine; Case-Control Studies; Citrulline; Cohort Studies; Diabetes Mellitus, Type 2; Diet, Fat-Restricted; Diet, Mediterranean; Female; Humans; Incidence; Insulin Resistance; Male; Middle Aged; omega-N-Methylarginine; Ornithine; Risk Factors

2019
Homoarginine/ADMA ratio and homoarginine/SDMA ratio as independent predictors of cardiovascular mortality and cardiovascular events in lower extremity arterial disease.
    Scientific reports, 2018, 09-21, Volume: 8, Issue:1

    Topics: Aged; Arginine; Biomarkers; Cardiovascular Diseases; Cardiovascular System; Female; Homoarginine; Humans; Incidence; Lower Extremity; Male; Middle Aged; Prospective Studies; Risk Factors; Vascular Diseases

2018
AGXT2 and DDAH-1 genetic variants are highly correlated with serum ADMA and SDMA levels and with incidence of coronary artery disease in Egyptians.
    Molecular biology reports, 2018, Volume: 45, Issue:6

    Topics: Adult; Amidohydrolases; Arginine; Case-Control Studies; Coronary Artery Disease; Egypt; Female; Genetic Variation; Genotype; Humans; Incidence; Male; Middle Aged; Nitric Oxide; Polymorphism, Single Nucleotide; Transaminases

2018
Evidence for a protective role for the rs805305 single nucleotide polymorphism of dimethylarginine dimethylaminohydrolase 2 (DDAH2) in septic shock through the regulation of DDAH activity.
    Critical care (London, England), 2018, 12-11, Volume: 22, Issue:1

    Topics: Amidohydrolases; Arginine; Biomarkers; Humans; Organ Dysfunction Scores; Polymorphism, Single Nucleotide; Protective Agents; Shock, Septic; Statistics, Nonparametric; Time Factors

2018
Guanidino compound ratios are associated with stroke etiology, internal carotid artery stenosis and CHA
    Journal of the neurological sciences, 2019, 02-15, Volume: 397

    Topics: Aged; Arginine; Biomarkers; Brain Ischemia; Carotid Arteries; Carotid Stenosis; Cross-Sectional Studies; Female; Homoarginine; Humans; Intracranial Hemorrhages; Male; Middle Aged; Recurrence; Stroke

2019
Total methylated arginine load as a risk parameter in subjects with masked hypertension.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 2020, Volume: 42, Issue:2

    Topics: Arginine; Biomarkers; Blood Pressure Determination; Female; Humans; Hypertension; Male; Masked Hypertension; Middle Aged; Nitric Oxide; omega-N-Methylarginine; Risk Factors

2020
Asymmetric dimethylarginine as a potential biomarker for management and follow-up of phenylketonuria.
    European journal of pediatrics, 2019, Volume: 178, Issue:6

    Topics: Arginine; Biomarkers; Case-Control Studies; Child; Creatinine; Cross-Sectional Studies; Diet, Protein-Restricted; Female; Humans; Male; Phenylketonurias; Spain

2019
Asymmetric and Symmetric Protein Arginine Dimethylation: Concept and Postprandial Effects of High-Fat Protein Meals in Healthy Overweight Men.
    Nutrients, 2019, Jun-27, Volume: 11, Issue:7

    Topics: Adult; Arginine; Biomarkers; Diet, High-Fat; Diet, High-Protein; Gas Chromatography-Mass Spectrometry; Humans; Interleukin-6; Male; Middle Aged; Overweight; Postprandial Period; Time Factors; Tumor Necrosis Factor-alpha; Urinalysis; Young Adult

2019
Establishment of reference values for the lysine acetylation marker N
    Amino acids, 2019, Volume: 51, Issue:9

    Topics: Adolescent; Adult; Arginine; Biomarkers; Cardiovascular Diseases; Carnitine; Chromatography, Liquid; Citrulline; Creatinine; Female; Homoarginine; Humans; Lysine; Male; Middle Aged; Ornithine; Reference Values; Renal Insufficiency, Chronic; Tandem Mass Spectrometry; Young Adult

2019
Metabolites of the Nitric Oxide (NO) Pathway Are Altered and Indicative of Reduced NO and Arginine Bioavailability in Patients with Cardiometabolic Diseases Complicated with Chronic Wounds of Lower Extremities: Targeted Metabolomics Approach (LC-MS/MS).
    Oxidative medicine and cellular longevity, 2019, Volume: 2019

    Topics: Aged; Arginine; Cardiovascular Diseases; Case-Control Studies; Chemokines; Citrulline; Cytokines; Female; Growth Hormone; Humans; Lower Extremity; Male; Metabolomics; Middle Aged; Nitric Oxide; Wounds and Injuries

2019
Targeted metabolomic analysis of nitric oxide/L-arginine pathway metabolites in dementia: association with pathology, severity, and structural brain changes.
    Scientific reports, 2019, 09-24, Volume: 9, Issue:1

    Topics: Arginine; Biomarkers; Brain; Citrulline; Dementia; Female; Humans; Male; Metabolomics; Middle Aged; Nitric Oxide; Signal Transduction

2019
Changes in Water Soluble Uremic Toxins and Urinary Acute Kidney Injury Biomarkers After 10- and 100-km Runs.
    International journal of environmental research and public health, 2019, 10-28, Volume: 16, Issue:21

    Topics: Acute Kidney Injury; Acute-Phase Proteins; Adult; Albuminuria; Arginine; Biomarkers; Creatinine; Female; Glomerular Filtration Rate; Humans; Lipocalin-2; Lipocalins; Male; Methylamines; Middle Aged; Running; Urea; Uric Acid; Water

2019
Arginine derivatives in atrial fibrillation progression phenotypes.
    Journal of molecular medicine (Berlin, Germany), 2020, Volume: 98, Issue:7

    Topics: Aged; Arginine; Atrial Fibrillation; Biomarkers; Cohort Studies; Disease Progression; Female; Homoarginine; Humans; Male; Middle Aged; Phenotype

2020
Increased symmetric dimethylarginine, but not asymmetric dimethylarginine, concentrations are associated with transient myocardial ischemia and predict outcome.
    The Journal of international medical research, 2020, Volume: 48, Issue:6

    Topics: Aged; Arginine; Biomarkers; Coronary Angiography; Coronary Artery Disease; Coronary Vessels; Dipyridamole; Female; Follow-Up Studies; Heart; Heart Function Tests; Humans; Male; Middle Aged; Myocardial Perfusion Imaging; Prospective Studies; Risk Assessment; Tomography, X-Ray Computed

2020
Comprehensive arginine metabolomics and peripheral vasodilatory capacity in rheumatoid arthritis: A monocentric cross-sectional study.
    Microvascular research, 2020, Volume: 131

    Topics: Aged; Aged, 80 and over; Arginine; Arthritis, Rheumatoid; Biomarkers; Case-Control Studies; Citrulline; Cross-Sectional Studies; Female; Fingers; Homoarginine; Humans; Italy; Male; Metabolomics; Middle Aged; Vasodilation

2020
Increased Intraplatelet ADMA Level May Promote Platelet Activation in Diabetes Mellitus.
    Oxidative medicine and cellular longevity, 2020, Volume: 2020

    Topics: Adenosine Diphosphate; Adult; Aged; Arginine; Blood Platelets; Calcium; Case-Control Studies; Chromatography, High Pressure Liquid; Diabetes Mellitus, Type 2; Female; Humans; Male; Mass Spectrometry; Middle Aged; Nitric Oxide; Platelet Activation; Platelet Aggregation; Risk Factors

2020
Asymmetric dimethylarginine-A potential cardiac biomarker in horses.
    Journal of veterinary cardiology : the official journal of the European Society of Veterinary Cardiology, 2021, Volume: 33

    Topics: Animals; Arginine; Biomarkers; Enzyme-Linked Immunosorbent Assay; Female; Heart Diseases; Horse Diseases; Horses; Male; Prospective Studies; Reference Values

2021
Evaluation of Biomarkers in Sepsis: High Dimethylarginine (ADMA and SDMA) Concentrations Are Associated with Mortality.
    The journal of applied laboratory medicine, 2021, 04-29, Volume: 6, Issue:3

    Topics: Arginine; Biomarkers; Humans; Sepsis

2021
Intrathecal and systemic alterations of L-arginine metabolism in patients after intracerebral hemorrhage.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2021, Volume: 41, Issue:8

    Topics: Aged; Arginine; Case-Control Studies; Cerebral Hemorrhage; Chromatography, High Pressure Liquid; Citrulline; Female; Humans; Male; Middle Aged; Nitric Oxide; Nitric Oxide Synthase; Ornithine; Risk Factors; Tandem Mass Spectrometry; Up-Regulation

2021
Lack of evidence of the correlation between plasma Asymmetrical Dimethylarginine correlation and IMT in type 2 diabetic patients with chronic vascular complication.
    Acta biochimica Polonica, 2021, Feb-05, Volume: 68, Issue:1

    Topics: Adult; Aged; Arginine; Atherosclerosis; Carotid Artery, Internal; Carotid Intima-Media Thickness; Case-Control Studies; Chronic Disease; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Humans; Male; Middle Aged; Risk Factors; Ultrasonography, Doppler, Color

2021
Is there a relation between serum methylarginine levels and infertility?
    Hormone molecular biology and clinical investigation, 2021, Jan-27, Volume: 42, Issue:3

    Topics: Adult; Arginine; Biomarkers; Disease Susceptibility; Humans; Infertility; Male; Oligospermia; ROC Curve; Semen Analysis; Sperm Count; Young Adult

2021
Altered methylarginine levels after surgery in subjects with multinodular goiter.
    Hormone molecular biology and clinical investigation, 2021, Feb-22, Volume: 42, Issue:3

    Topics: Adult; Arginine; Biomarkers; Case-Control Studies; Chromatography, High Pressure Liquid; Female; Goiter, Nodular; Humans; Male; Middle Aged; omega-N-Methylarginine; Postoperative Period; Sensitivity and Specificity

2021
Whole-body arginine dimethylation is associated with all-cause mortality in adult renal transplant recipients.
    Amino acids, 2021, Volume: 53, Issue:4

    Topics: Adult; Aged; Arginine; Biomarkers; Cardiovascular Diseases; Cause of Death; Female; Heart Disease Risk Factors; Humans; Kidney Transplantation; Male; Methylation; Middle Aged; Protein Processing, Post-Translational; Tissue Donors; Transplant Recipients

2021
Electrophoretic Determination of Symmetric and Asymmetric Dimethylarginine in Human Blood Plasma with Whole Capillary Sample Injection.
    International journal of molecular sciences, 2021, Mar-15, Volume: 22, Issue:6

    Topics: Acetonitriles; Anions; Arginine; Electric Conductivity; Electrophoresis, Capillary; Humans; Limit of Detection

2021
Elevated serum SDMA and ADMA at hospital admission predict in-hospital mortality of COVID-19 patients.
    Scientific reports, 2021, 05-10, Volume: 11, Issue:1

    Topics: Aged; Aged, 80 and over; Arginine; Biomarkers; Cohort Studies; COVID-19; Female; Hospital Mortality; Hospitalization; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Risk Factors; SARS-CoV-2

2021
Evaluation of serum neutrophil gelatinase-associated lipocalin (NGAL), asymmetric dimethylarginine (ADMA) and symmetric dimethylarginine (SDMA) levels, and their relations with disease type and activity in inflammatory bowel diseases
    Turkish journal of medical sciences, 2021, 10-21, Volume: 51, Issue:5

    Topics: Adult; Aged; Arginine; Biomarkers; Colitis, Ulcerative; Crohn Disease; Female; Humans; Inflammatory Bowel Diseases; Lipocalin-2; Male; Middle Aged

2021
Serum L-arginine and endogenous methylarginine concentrations predict irritable bowel syndrome in adults: A nested case-control study.
    United European gastroenterology journal, 2021, Volume: 9, Issue:7

    Topics: Aged; Aged, 80 and over; Arginine; Biomarkers; Case-Control Studies; Cohort Studies; Female; Humans; Irritable Bowel Syndrome; Logistic Models; Male; Middle Aged; Nitric Oxide; Odds Ratio; Psychological Distress; ROC Curve

2021
Associations of circulating dimethylarginines with the metabolic syndrome in the Framingham Offspring study.
    PloS one, 2021, Volume: 16, Issue:9

    Topics: Arginine; Biomarkers; Cross-Sectional Studies; Female; Humans; Male; Metabolic Syndrome; Middle Aged; Prevalence; Prospective Studies; Tandem Mass Spectrometry

2021
Characterization of the L-Arginine/Nitric Oxide Pathway and Oxidative Stress in Pediatric Patients with Atopic Diseases.
    International journal of molecular sciences, 2022, Feb-15, Volume: 23, Issue:4

    Topics: Arginine; Asthma; Child; Dermatitis, Atopic; Female; Homoarginine; Humans; Male; Malondialdehyde; Nitrates; Nitric Oxide; Nitrites; Oxidative Stress; Signal Transduction

2022
Design and validation of an LC-MS/MS method for simultaneous quantification of asymmetric dimethylguanidino valeric acid, asymmetric dimethylarginine and symmetric dimethylarginine in human plasma.
    Pathology, 2022, Volume: 54, Issue:5

    Topics: Arginine; Cardiovascular Diseases; Chromatography, High Pressure Liquid; Chromatography, Liquid; Female; Humans; Male; Non-alcoholic Fatty Liver Disease; Tandem Mass Spectrometry

2022
Association of serum ADMA, SDMA and L-NMMA concentrations with disease progression in COVID-19 patients.
    Biochemia medica, 2023, Feb-15, Volume: 33, Issue:1

    Topics: Arginine; COVID-19; Disease Progression; Humans; omega-N-Methylarginine

2023
Urinary excretion of asymmetric (ADMA) and symmetric (SDMA) dimethylarginine is positively related to nitric oxide level in tissues of normotensive and hypertensive rats.
    Amino acids, 2023, Volume: 55, Issue:4

    Topics: Animals; Arginine; Chromatography, Liquid; Citrulline; Hypertension; Male; Nitric Oxide; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Tandem Mass Spectrometry

2023