Page last updated: 2024-09-03

n,n-dimethylarginine and sapropterin

n,n-dimethylarginine has been researched along with sapropterin in 11 studies

Compound Research Comparison

Studies
(n,n-dimethylarginine)
Trials
(n,n-dimethylarginine)
Recent Studies (post-2010)
(n,n-dimethylarginine)
Studies
(sapropterin)
Trials
(sapropterin)
Recent Studies (post-2010) (sapropterin)
2,2162281,2212,36293614

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's8 (72.73)29.6817
2010's3 (27.27)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kurabayashi, M; Morita, H; Nagai, R; Nakamura, T; Saito, Y1
Hirata, Y1
Boucher, JL; Brunet, A; David-Dufilho, M; Devynck, MA; Millanvoye, E; Rendu, F; Topal, G1
Kajiya, F; Kashihara, N; Kimoto, M; Miyasaka, T; Mochizuki, S; Ogasawara, Y; Ono, J; Yada, T1
Bryan, RM; Durante, W; Jiang, X; Liao, D; Randhawa, JK; Rumbaut, RE; Schafer, AI; Tan, H; Wang, H; Yang, F; Yang, X1
Ayajiki, K; Gemba, M; Okamura, T; Shinozaki, K; Yamamizu, K1
Akasaka, T; Kaji, S; Kajiya, F; Mochizuki, S; Ogasawara, Y; Tanemoto, K; Yada, T; Yoshida, K1
Cardounel, AJ; Chen, CA; Druhan, LJ; Forbes, SP; Pope, AJ; Zweier, JL1
Förstermann, U1
Aramburo, A; Black, SM; Fineman, JR; Kalkan, G; Kallarackal, S; Kumar, S; Rafikov, R; Rehmani, I; Sharma, S; Sun, X; Tian, J1
Fung, HL; Mohan, S1

Reviews

3 review(s) available for n,n-dimethylarginine and sapropterin

ArticleYear
[Involvement of homocysteine in the pathogenesis of hypertension and hypertensive target-organ damage].
    Nihon rinsho. Japanese journal of clinical medicine, 2004, Volume: 62 Suppl 3

    Topics: Arginine; Arteriosclerosis; Biopterins; Cell Division; Endothelium, Vascular; Folic Acid; Homocysteine; Humans; Hypertension; Insulin Resistance; Muscle, Smooth, Vascular; Nitric Oxide; Oxidative Stress; Risk Factors

2004
[NO and hypertension].
    Nihon rinsho. Japanese journal of clinical medicine, 2004, Volume: 62 Suppl 3

    Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Arginine; Arteriosclerosis; Biopterins; C-Reactive Protein; Endothelium, Vascular; Humans; Hypertension; Mutation; NADPH Oxidases; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Perindopril; Reactive Oxygen Species; Vasodilation

2004
Nitric oxide and oxidative stress in vascular disease.
    Pflugers Archiv : European journal of physiology, 2010, Volume: 459, Issue:6

    Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Antioxidants; Arginine; Aryldialkylphosphatase; Biopterins; Calcium; Cardiovascular Diseases; Catalase; Electron Transport; Glutathione Peroxidase; Heme Oxygenase (Decyclizing); Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Mitochondria; NADPH Oxidases; Nitric Oxide; Nitric Oxide Synthase Type III; Oxidative Stress; Phosphorylation; Protein Multimerization; Reactive Oxygen Species; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Risk Factors; Superoxide Dismutase; Superoxides; Thioredoxins; Vascular Diseases; Xanthine Oxidase

2010

Other Studies

8 other study(ies) available for n,n-dimethylarginine and sapropterin

ArticleYear
Homocysteine induces oxidative stress by uncoupling of NO synthase activity through reduction of tetrahydrobiopterin.
    Free radical biology & medicine, 2004, Jun-15, Volume: 36, Issue:12

    Topics: Antioxidants; Arginine; Ascorbic Acid; Biopterins; Blotting, Western; Cells, Cultured; Dose-Response Relationship, Drug; Endothelium, Vascular; Ethidium; Fluorescent Dyes; Homocysteine; Humans; L-Lactate Dehydrogenase; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Oxidative Stress; Phosphorylation; Pterins; Reactive Nitrogen Species; Superoxides; Thrombin; Time Factors

2004
Systemic nitric oxide production rate during hemodialysis and its relationship with nitric oxide-related factors.
    Blood purification, 2005, Volume: 23, Issue:4

    Topics: Arginine; Biopterins; Blood Pressure; Female; Humans; Lipoproteins, LDL; Male; Middle Aged; Nitrates; Nitric Oxide; Renal Dialysis

2005
Hyperhomocystinemia impairs endothelial function and eNOS activity via PKC activation.
    Arteriosclerosis, thrombosis, and vascular biology, 2005, Volume: 25, Issue:12

    Topics: Animals; Antioxidants; Aorta, Thoracic; Arginine; Biopterins; Cells, Cultured; Cystathionine beta-Synthase; Endothelium, Vascular; Enzyme Activation; Female; Gene Expression Regulation, Enzymologic; Glutathione Peroxidase; Glutathione Peroxidase GPX1; Homocysteine; Humans; Hyperhomocysteinemia; Male; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Protein Kinase C; Pterins; Superoxide Dismutase; Vasodilation

2005
Oral administration of both tetrahydrobiopterin and L-arginine prevents endothelial dysfunction in rats with chronic renal failure.
    Journal of cardiovascular pharmacology, 2007, Volume: 49, Issue:3

    Topics: Acetylcholine; Administration, Oral; Animals; Aorta; Arginine; Biopterins; Blood Pressure; Calcimycin; Drug Synergism; Drug Therapy, Combination; Endothelium, Vascular; Kidney Failure, Chronic; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type III; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Superoxides

2007
Changes of asymmetric dimethylarginine, nitric oxide, tetrahydrobiopterin, and oxidative stress in patients with acute myocardial infarction by medical treatments.
    Clinical hemorheology and microcirculation, 2007, Volume: 37, Issue:3

    Topics: Adult; Aged; Arginine; Biopterins; Case-Control Studies; Drug Therapy; Endothelium, Vascular; Female; Humans; Lipoproteins, LDL; Male; Middle Aged; Myocardial Infarction; Nitric Oxide; Oxidative Stress; Superoxides

2007
Regulation of eNOS-derived superoxide by endogenous methylarginines.
    Biochemistry, 2008, Jul-08, Volume: 47, Issue:27

    Topics: Arginine; Biopterins; Electron Spin Resonance Spectroscopy; Heme; Humans; NADP; Nitric Oxide Synthase Type III; omega-N-Methylarginine; Superoxides

2008
Preserving mitochondrial function prevents the proteasomal degradation of GTP cyclohydrolase I.
    Free radical biology & medicine, 2012, Jul-15, Volume: 53, Issue:2

    Topics: Acetylcarnitine; Adaptor Proteins, Signal Transducing; Animals; Animals, Newborn; Arginine; Biopterins; Disease Models, Animal; Endothelial Cells; Female; GTP Cyclohydrolase; HSP70 Heat-Shock Proteins; Hypertension, Pulmonary; Mitochondria; Nitric Oxide; Nitric Oxide Synthase; Pregnancy; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Pulmonary Artery; Pulmonary Heart Disease; Sheep; Signal Transduction; Ubiquitin-Protein Ligases; Ubiquitination

2012
Mechanism of cellular oxidation stress induced by asymmetric dimethylarginine.
    International journal of molecular sciences, 2012, Volume: 13, Issue:6

    Topics: Arginine; Biopterins; Enzyme Inhibitors; Human Umbilical Vein Endothelial Cells; Humans; Lysine; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide Synthase Type III; Nitrites; Oxidative Stress

2012