n,n-dimethylarginine has been researched along with probucol in 5 studies
| Studies (n,n-dimethylarginine) | Trials (n,n-dimethylarginine) | Recent Studies (post-2010) (n,n-dimethylarginine) | Studies (probucol) | Trials (probucol) | Recent Studies (post-2010) (probucol) |
|---|---|---|---|---|---|
| 2,216 | 228 | 1,221 | 1,488 | 174 | 317 |
| Protein | Taxonomy | n,n-dimethylarginine (IC50) | probucol (IC50) |
|---|---|---|---|
| NAD-dependent protein deacylase sirtuin-5, mitochondrial | Homo sapiens (human) | 1.6 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (60.00) | 29.6817 |
| 2010's | 2 (40.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Deng, HW; Jiang, JL; Li Ns, NS; Li, YJ | 1 |
| Espey, MG; Harvey-White, J; Jung, CS; Oldfield, EH; Pluta, RM; Shilad, S; Whitehead, A | 1 |
| Deng, HW; Hu, CP; Jiang, JL; Li, NS; Li, YJ; Rang, WQ; Zhang, XH | 1 |
| Li, X; Ma, JP; Wang, CX; Wang, L; Wu, CJ; Xia, XS | 1 |
| Fu, Q; Hu, LL; Tian, T; Zhang, H; Zhang, KQ | 1 |
1 trial(s) available for n,n-dimethylarginine and probucol
| Article | Year |
|---|---|
[Impact of adding folic acid, vitamin B(12) and probucol to standard antihypertensive medication on plasma homocysteine and asymmetric dimethylarginine levels of essential hypertension patients].
Topics: Aged; Antihypertensive Agents; Arginine; Female; Folic Acid; Homocysteine; Humans; Hypertension; Male; Middle Aged; Nitric Oxide; Nitric Oxide Synthase Type III; Plasma; Probucol; Vitamin B 12; Vitamin B Complex; Vitamins | 2012 |
4 other study(ies) available for n,n-dimethylarginine and probucol
| Article | Year |
|---|---|
Probucol preserves endothelial function by reduction of the endogenous nitric oxide synthase inhibitor level.
Topics: Animals; Aorta, Thoracic; Arginine; Endothelium, Vascular; Enzyme Inhibitors; Lipoproteins, LDL; Male; Malondialdehyde; Muscle, Smooth, Vascular; Nitric Oxide Synthase; Probucol; Rats; Rats, Sprague-Dawley; Vasodilation | 2002 |
In vitro and in vivo effects of probucol on hydrolysis of asymmetric dimethyl L-arginine and vasospasm in primates.
Topics: Animals; Antioxidants; Arginine; Bilirubin; Cell Culture Techniques; Double-Blind Method; Endothelial Cells; Enzyme Inhibitors; Hydrolysis; Lipid Peroxidation; Macaca fascicularis; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Oxidation-Reduction; Placebos; Probucol; Random Allocation; Subarachnoid Hemorrhage; Time Factors; Umbilical Veins; Vasospasm, Intracranial | 2005 |
Probucol decreases asymmetrical dimethylarginine level by alternation of protein arginine methyltransferase I and dimethylarginine dimethylaminohydrolase activity.
Topics: Amidohydrolases; Antioxidants; Arginine; Cell Line; Endothelial Cells; Humans; L-Lactate Dehydrogenase; Lipoproteins, LDL; Malondialdehyde; Nitric Oxide; Nitric Oxide Synthase Type III; Probucol; Protein-Arginine N-Methyltransferases | 2006 |
Probucol improves erectile function via Activation of Nrf2 and coordinates the HO-1 / DDAH / PPAR-γ/ eNOS pathways in streptozotocin-induced diabetic rats.
Topics: Amidohydrolases; Animals; Arginine; Blood Glucose; Body Weight; Cyclic GMP; Diabetes Mellitus, Experimental; Erectile Dysfunction; Heme Oxygenase-1; Male; Malondialdehyde; NF-E2-Related Factor 2; Nitric Oxide Synthase Type III; PPAR gamma; Probucol; Rats, Sprague-Dawley; Signal Transduction; Streptozocin; Superoxide Dismutase | 2018 |