n,n-dimethylarginine and ng-nitroarginine methyl ester
n,n-dimethylarginine has been researched along with ng-nitroarginine methyl ester in 39 studies
Compound Research Comparison
| Studies (n,n-dimethylarginine) | Trials (n,n-dimethylarginine) | Recent Studies (post-2010) (n,n-dimethylarginine) | Studies (ng-nitroarginine methyl ester) | Trials (ng-nitroarginine methyl ester) | Recent Studies (post-2010) (ng-nitroarginine methyl ester) |
|---|---|---|---|---|---|
| 2,216 | 228 | 1,221 | 12,640 | 117 | 2,342 |
Protein Interaction Comparison
| Protein | Taxonomy | n,n-dimethylarginine (IC50) | ng-nitroarginine methyl ester (IC50) |
|---|---|---|---|
| Neutrophil elastase | Homo sapiens (human) | 2.7 | |
| Nitric oxide synthase, endothelial | Homo sapiens (human) | 2.1 | |
| Nitric oxide synthase, brain | Homo sapiens (human) | 1.1167 | |
| Nitric oxide synthase, inducible | Mus musculus (house mouse) | 2.6 | |
| Nitric oxide synthase, inducible | Homo sapiens (human) | 8 | |
| Collagenase 3 | Homo sapiens (human) | 2.7 |
Research
Studies (39)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (7.69) | 18.2507 |
| 2000's | 20 (51.28) | 29.6817 |
| 2010's | 14 (35.90) | 24.3611 |
| 2020's | 2 (5.13) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Fickling, SA; MacAllister, RJ; Vallance, P; Whitley, GS | 1 |
| Granger, DN; Grisham, MB; Kurose, I; Wolf, R | 1 |
| Barefield, D; Ram, S; White, R; Work, J | 1 |
| Kimura, K; Masuyama, Y; Nishio, I; Tsuda, K | 1 |
| Kimura, K; Masuyama, Y; Nishio, I; Shimamoto, Y; Tsuda, K | 1 |
| Kimura, K; Kinoshita, Y; Masuyama, Y; Nishio, I; Tsuda, K | 1 |
| Azuma, H; Goto, M; Kihara, K; Masuda, H; Okuno, T; Tsujii, T | 1 |
| Cooke, JP; Losordo, DW | 1 |
| Bode-Böger, SM; Fliser, D; Frölich, JC; Haller, H; Hoeper, MM; Impraim, B; Kielstein, JT; Simmel, S; Tsikas, D | 1 |
| Goligorsky, MS; Kajstura, M; Sawamura, T; Smirnova, IV | 1 |
| Dietz, S; Faurie, F; Gross, R; Lajoix, AD; Linck, N; Mani, JC; Petit, P; Pugnière, M; Ribes, G; Roquet, F | 1 |
| Boucher, JL; Brunet, A; David-Dufilho, M; Devynck, MA; Millanvoye, E; Rendu, F; Topal, G | 1 |
| Hayashida, Y; Morishita, T; Nakashima, Y; Nakata, S; Sasaguri, Y; Suda, O; Tasaki, H; Toyohira, Y; Tsujimoto, T; Tsutsui, M; Ueno, S; Ueta, Y; Yanagihara, N | 1 |
| Nishio, I; Tsuda, K | 1 |
| Blau, HM; Cooke, JP; Dayoub, H; Jacobi, J; Kimoto, M; Patterson, AJ; Sydow, K; von Degenfeld, G; Wang, B; Zhang, Y | 1 |
| Augustyniak, RA; Morgan, DA; Victor, RG; Zhang, W | 1 |
| Buerk, DG; Carlsson, PO; Hansell, P; Liss, P; Palm, F | 1 |
| Augustyniak, RA; Thomas, GD; Victor, RG; Zhang, W | 1 |
| Fevery, J; Laleman, W; Nevens, F; Omasta, A; Roskams, T; Severi, T; Van de Casteele, M; Van Landeghem, L; van Pelt, J; Vander Elst, I; Zeegers, M | 1 |
| Bode-Böger, SM; Bukowska, A; Lendeckel, U; Martens-Lobenhoffer, J; Scalera, F; Täger, M | 1 |
| Ayajiki, K; Gemba, M; Okamura, T; Shinozaki, K; Yamamizu, K | 1 |
| Brown, RD; Carlström, M; Edlund, J; Larsson, E; Palm, F; Persson, AE; Sällström, J; Teerlink, T; Wåhlin, N | 1 |
| Chen, JS; Chen, JW; Chen, YH; Huang, PH; Lin, FY; Lin, SJ; Sata, M; Tsai, HY; Wu, TC | 1 |
| Meng, X; Shan, HY; Yi, TN; Zhang, J; Zhang, JS; Zhao, HY | 1 |
| Bigé, N; Boffa, JJ; Chatziantoniou, C; Dussaule, JC; Jouanneau, C; Mihout, F; Ronco, P; Shweke, N | 1 |
| Atzler, D; Bache, RJ; Böger, RH; Chen, Y; Fassett, J; Guo, H; Hu, X; Lu, Z; Schwedhelm, E; Xu, X; Zhang, P | 1 |
| Al-Zobaidy, MJ; Brown, K; Craig, J; Martin, W; Pettifor, G | 1 |
| Billecke, S; Chen, AF; Craig, T; D'Alecy, LG; Haywood, JR; Hinojosa-Laborde, C; Northcott, CA; Patel, KP | 1 |
| Hu, CP; Jiang, JL; Li, YJ; Nie, SD; Wang, S; Yuan, Q; Zhang, WF; Zhou, Z | 1 |
| Closs, EI; Daiber, A; Förstermann, U; Habermeier, A; Jabs, A; Münzel, T; Ostad, MA; Simon, A; Warnholtz, A | 1 |
| Fung, HL; Mohan, S | 1 |
| Helle, F; Hultström, M; Iversen, BM; Palm, F; Schwartz, D; Schwartz, IF; Skogstrand, T | 1 |
| Cheng, MC; Huang, LT; Tain, YL; Wu, TH | 1 |
| Chen, B; Chicoine, LG; Cui, H; Jin, Y; Nelin, LD; Strauch, K | 1 |
| Chakraborti, A; Gulati, K; Ray, A | 1 |
| Barančík, M; Berenyiová, A; Dovinová, I; Hrabárová, E; Jansen, E; Kvandová, M; Majzúnová, M | 1 |
| Cai, GW; Cheng, P; Ding, L; Gao, S; Hu, J; Huang, GY; Wang, L; Zhang, YX | 1 |
| Gulhan, MF; Ozdemir, B; Sahna, E; Selamoglu, Z | 1 |
| Kellum, JA; Lee, Y; Singh, J | 1 |
Reviews
2 review(s) available for n,n-dimethylarginine and ng-nitroarginine methyl ester
| Article | Year |
|---|---|
Nitric oxide pathway as new drug targets for refractory hypertension.
Topics: Animals; Antihypertensive Agents; Arginine; Blood Pressure; Endothelium, Vascular; Humans; Hypertension; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Signal Transduction; Superoxides | 2005 |
A new perspective on NO pathway in sepsis and ADMA lowering as a potential therapeutic approach.
Topics: Animals; Arginine; Humans; Ischemia; NG-Nitroarginine Methyl Ester; Nitric Oxide; Sepsis | 2022 |
Trials
2 trial(s) available for n,n-dimethylarginine and ng-nitroarginine methyl ester
| Article | Year |
|---|---|
Cardiovascular effects of systemic nitric oxide synthase inhibition with asymmetrical dimethylarginine in humans.
Topics: Arginine; Cardiac Output; Cross-Over Studies; Cyclic GMP; Dose-Response Relationship, Drug; Double-Blind Method; Enzyme Inhibitors; Hemodynamics; Humans; Kidney; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Vascular Resistance | 2004 |
Intake of red wine increases the number and functional capacity of circulating endothelial progenitor cells by enhancing nitric oxide bioavailability.
Topics: AC133 Antigen; Adult; Alcoholic Beverages; Antigens, CD; Antigens, CD34; Arginine; Beer; Biological Availability; Biomarkers; Cell Adhesion; Cell Movement; Cell Proliferation; Cells, Cultured; Cellular Senescence; Endothelial Cells; Enzyme Inhibitors; Ethanol; Female; Flow Cytometry; Glycoproteins; Humans; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type III; Peptides; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Prospective Studies; Proto-Oncogene Proteins c-akt; Resveratrol; Stem Cells; Stilbenes; Tumor Necrosis Factor-alpha; Up-Regulation; Vascular Endothelial Growth Factor Receptor-2; Vasodilation; Wine | 2010 |
Other Studies
35 other study(ies) available for n,n-dimethylarginine and ng-nitroarginine methyl ester
| Article | Year |
|---|---|
Metabolism of methylarginines by human vasculature; implications for the regulation of nitric oxide synthesis.
Topics: Amino Acid Oxidoreductases; Arginase; Arginine; Cells, Cultured; Chromatography, High Pressure Liquid; Citrulline; Cytosol; Endothelium, Vascular; Humans; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Saphenous Vein; Umbilical Veins | 1994 |
Effects of an endogenous inhibitor of nitric oxide synthesis on postcapillary venules.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Blood Flow Velocity; Blood Platelets; Cell Adhesion; Cell Aggregation; Endothelium, Vascular; Kinetics; Leukocytes; Male; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Splanchnic Circulation; Stereoisomerism; Venules | 1995 |
Peritoneal dialysis solutions reverse the hemodynamic effects of nitric oxide synthesis inhibitors.
Topics: Animals; Arginine; Dialysis Solutions; Enzyme Inhibitors; Hemodynamics; Male; Mesenteric Arteries; NG-Nitroarginine Methyl Ester; Nitric Oxide; Peritoneal Dialysis; Rats; Rats, Sprague-Dawley; Renal Insufficiency | 1995 |
Nitric oxide improves membrane fluidity of erythrocytes in essential hypertension: An electron paramagnetic resonance investigation.
Topics: Arginine; Blood Pressure; Calcimycin; Cell Membrane; Cyclic GMP; Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Erythrocytes; Hemorheology; Humans; Hypertension; Membrane Fluidity; Middle Aged; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Penicillamine; Spin Labels | 2000 |
Estriol improves membrane fluidity of erythrocytes by the nitric oxide-dependent mechanism: an electron paramagnetic resonance study.
Topics: Arginine; Cyclic GMP; Electron Spin Resonance Spectroscopy; Enzyme Inhibitors; Erythrocyte Membrane; Estriol; Female; Humans; In Vitro Techniques; Male; Membrane Fluidity; Middle Aged; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Penicillamine | 2001 |
Electron paramagnetic resonance investigation on modulatory effect of 17beta-estradiol on membrane fluidity of erythrocytes in postmenopausal women.
Topics: Aged; Arginine; Cyclic GMP; Electron Spin Resonance Spectroscopy; Erythrocytes; Estradiol; Female; Humans; Hypertension; In Vitro Techniques; Membrane Fluidity; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Penicillamine; Postmenopause; S-Nitroso-N-Acetylpenicillamine | 2001 |
Localization and role of nitric oxide synthase and endogenous nitric oxide synthase inhibitors in the rabbit lower urinary tract.
Topics: Animals; Arginine; Culture Techniques; Enzyme Inhibitors; Muscle Relaxation; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rabbits; Urethra; Urinary Bladder | 2002 |
Nitric oxide and angiogenesis.
Topics: Angiogenesis Inhibitors; Angiostatins; Animals; Arginine; Arteriosclerosis; Coronary Circulation; Dogs; Endothelium, Vascular; Matrix Metalloproteinases; Myocardial Ischemia; Neovascularization, Physiologic; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Peptide Fragments; Plasminogen | 2002 |
Asymmetric dimethylarginine upregulates LOX-1 in activated macrophages: role in foam cell formation.
Topics: Arginine; Cell Differentiation; Endothelium, Vascular; Enzyme Inhibitors; Foam Cells; Free Radical Scavengers; HL-60 Cells; Humans; Lipoproteins, LDL; Macrophages; Metalloporphyrins; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Receptors, Cell Surface; Receptors, LDL; RNA, Small Interfering; Umbilical Veins; Up-Regulation | 2004 |
Changes in the dimeric state of neuronal nitric oxide synthase affect the kinetics of secretagogue-induced insulin response.
Topics: Animals; Arginine; Carrier Proteins; Cell Line; Dimerization; Drosophila Proteins; Dyneins; Enzyme Inhibitors; Glucose; Indazoles; Insulin; Insulin Secretion; Kinetics; Male; Miconazole; NG-Nitroarginine Methyl Ester; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitroarginine; Nitroprusside; Rats; Rats, Wistar; Surface Plasmon Resonance | 2004 |
Homocysteine induces oxidative stress by uncoupling of NO synthase activity through reduction of tetrahydrobiopterin.
Topics: Antioxidants; Arginine; Ascorbic Acid; Biopterins; Blotting, Western; Cells, Cultured; Dose-Response Relationship, Drug; Endothelium, Vascular; Ethidium; Fluorescent Dyes; Homocysteine; Humans; L-Lactate Dehydrogenase; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Oxidative Stress; Phosphorylation; Pterins; Reactive Nitrogen Species; Superoxides; Thrombin; Time Factors | 2004 |
Asymmetric dimethylarginine produces vascular lesions in endothelial nitric oxide synthase-deficient mice: involvement of renin-angiotensin system and oxidative stress.
Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Arginine; Coronary Disease; Enzyme Induction; Homocysteine; Imidazoles; Infusion Pumps, Implantable; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Microcirculation; Myocardium; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Nitrites; Olmesartan Medoxomil; omega-N-Methylarginine; Oxidative Stress; Peptidyl-Dipeptidase A; Renin-Angiotensin System; Superoxides; Tetrazoles; Thiazepines | 2004 |
A calcium channel blocker, benidipine, improves cell membrane fluidity in human subjects via a nitric oxide-dependent mechanism. An electron paramagnetic resonance investigation.
Topics: Aged; Arginine; Calcium Channel Blockers; Cell Membrane; Cyclic GMP; Dihydropyridines; Dose-Response Relationship, Drug; Electron Spin Resonance Spectroscopy; Enzyme Inhibitors; Erythrocytes; Female; Hemorheology; Humans; Male; Membrane Fluidity; Middle Aged; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Penicillamine; Viscosity | 2004 |
Overexpression of dimethylarginine dimethylaminohydrolase reduces tissue asymmetric dimethylarginine levels and enhances angiogenesis.
Topics: Amidohydrolases; Animals; Arginine; Enzyme Induction; Female; Hindlimb; Humans; Ischemia; Laser-Doppler Flowmetry; Mice; Mice, Transgenic; Microspheres; Muscle, Skeletal; Neovascularization, Physiologic; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Prostheses and Implants; Recombinant Fusion Proteins | 2005 |
L-NAME- and ADMA-induced sympathetic neural activation in conscious rats.
Topics: Animals; Arginine; Baroreflex; Consciousness; Female; Kidney; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Sinoatrial Node; Sympathectomy; Sympathetic Nervous System | 2006 |
Reduced nitric oxide concentration in the renal cortex of streptozotocin-induced diabetic rats: effects on renal oxygenation and microcirculation.
Topics: Animals; Arginine; Diabetes Mellitus, Experimental; Kidney Cortex; Male; Microcirculation; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxidative Stress; Oxygen; Rats; Rats, Inbred WF; Renal Circulation | 2005 |
A role for asymmetric dimethylarginine in the pathophysiology of portal hypertension in rats with biliary cirrhosis.
Topics: Acetylcholine; Animals; Arginine; Hypertension, Portal; Liver; Liver Cirrhosis, Biliary; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type III; Rats; Rats, Wistar; Thioacetamide; Vasodilation | 2005 |
Effect of L-arginine on asymmetric dimethylarginine (ADMA) or homocysteine-accelerated endothelial cell aging.
Topics: Aging; Arginine; Cells, Cultured; Cellular Senescence; Endothelial Cells; Endothelium, Vascular; Homocysteine; Humans; NG-Nitroarginine Methyl Ester; Oxidative Stress; Telomerase; Time Factors | 2006 |
Oral administration of both tetrahydrobiopterin and L-arginine prevents endothelial dysfunction in rats with chronic renal failure.
Topics: Acetylcholine; Administration, Oral; Animals; Aorta; Arginine; Biopterins; Blood Pressure; Calcimycin; Drug Synergism; Drug Therapy, Combination; Endothelium, Vascular; Kidney Failure, Chronic; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type III; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Superoxides | 2007 |
Role of nitric oxide deficiency in the development of hypertension in hydronephrotic animals.
Topics: Animals; Arginine; Blood Pressure; Disease Models, Animal; Diuresis; Enzyme Inhibitors; Hydronephrosis; Hypertension; Indazoles; Kidney; Kidney Cortex; Kidney Tubules, Proximal; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type III; Potassium; Rats; Rats, Sprague-Dawley; Sodium; Sodium Chloride, Dietary; Ureteral Obstruction | 2008 |
Effect of aspirin on high glucose-induced senescence of endothelial cells.
Topics: Anthracenes; Anti-Inflammatory Agents, Non-Steroidal; Arginine; Aspirin; Caveolin 1; Cells, Cultured; Cellular Senescence; Chromatography, High Pressure Liquid; Endothelial Cells; Flow Cytometry; Glucose; Humans; Immunoblotting; Immunoprecipitation; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type III; Propane; Reactive Oxygen Species | 2009 |
Asymmetric dimethylarginine (ADMA) induces chronic kidney disease through a mechanism involving collagen and TGF-β1 synthesis.
Topics: Animals; Arginine; Collagen; Endothelin-1; Enzyme Inhibitors; Fibrosis; Gene Expression Regulation; Hypertension; Hypoxia-Inducible Factor 1, alpha Subunit; Kidney; Male; Mice; Mice, Inbred Strains; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Oxidative Stress; Renal Insufficiency, Chronic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Transforming Growth Factor beta1 | 2011 |
Dimethylarginine dimethylaminohydrolase-1 is the critical enzyme for degrading the cardiovascular risk factor asymmetrical dimethylarginine.
Topics: Amidohydrolases; Animals; Arginine; Blood Pressure; Cardiovascular Diseases; Cells, Cultured; Endothelial Cells; Enzyme Inhibitors; Female; Genotype; Hypertension; Infusion Pumps, Implantable; Male; Mice; Mice, 129 Strain; Mice, Knockout; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Phenotype; Risk Factors; RNA Interference; Substrate Specificity; Time Factors; Transfection | 2011 |
Stimulus-specific blockade of nitric oxide-mediated dilatation by asymmetric dimethylarginine (ADMA) and monomethylarginine (L-NMMA) in rat aorta and carotid artery.
Topics: Animals; Aorta; Arginine; Carotid Arteries; Female; Male; Naphthyridines; NG-Nitroarginine Methyl Ester; Nitric Oxide; omega-N-Methylarginine; Phenylephrine; Pyrimidines; Rats; Rats, Wistar; Superoxide Dismutase; Vasodilation | 2011 |
Nitric oxide synthase, ADMA, SDMA, and nitric oxide activity in the paraventricular nucleus throughout the etiology of renal wrap hypertension.
Topics: Animals; Arginine; Blood Pressure; Disease Models, Animal; Enzyme Inhibitors; Hypertension, Renal; Kidney; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Paraventricular Hypothalamic Nucleus; Rats; Rats, Sprague-Dawley | 2012 |
Dimethylarginine dimethylaminohydrolase 1 regulates nerve growth factor-promoted differentiation of PC12 cells in a nitric oxide-dependent but asymmetric dimethylargenine-independent manner.
Topics: Amidohydrolases; Analysis of Variance; Animals; Arginine; Cell Differentiation; Enzyme Inhibitors; Microtubule-Associated Proteins; Nerve Growth Factor; Neurites; Neurons; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; PC12 Cells; Rats; RNA, Messenger; Transfection | 2012 |
Impairment of the extrusion transporter for asymmetric dimethyl-L-arginine: a novel mechanism underlying vasospastic angina.
Topics: Adult; Angina Pectoris; Arginine; Blood Platelets; Coronary Vasospasm; Endothelium, Vascular; Enzyme Inhibitors; Humans; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type III; Superoxides | 2012 |
Mechanism of cellular oxidation stress induced by asymmetric dimethylarginine.
Topics: Arginine; Biopterins; Enzyme Inhibitors; Human Umbilical Vein Endothelial Cells; Humans; Lysine; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide Synthase Type III; Nitrites; Oxidative Stress | 2012 |
Nitric oxide in afferent arterioles after uninephrectomy depends on extracellular L-arginine.
Topics: Angiotensin II; Animals; Arginine; Arterioles; Blood Pressure; Body Weight; Enzyme Inhibitors; Extracellular Space; Glomerular Filtration Rate; Homeostasis; Male; Nephrectomy; NG-Nitroarginine Methyl Ester; Nitric Oxide; Organ Size; Rats; Rats, Wistar; Renal Circulation; Vasoconstrictor Agents | 2013 |
Renoprotective effects of melatonin in young spontaneously hypertensive rats with L-NAME.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Amidohydrolases; Animals; Antioxidants; Arginine; Blood Pressure; Deoxyguanosine; Humans; Hypertension; Hypertension, Renal; Kidney; Male; Melatonin; Nephritis; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Inbred SHR | 2014 |
Asymmetric dimethylarginine does not inhibit arginase activity and is pro-proliferative in pulmonary endothelial cells.
Topics: Animals; Arginase; Arginine; Cattle; Cell Proliferation; Endothelial Cells; Lung; NG-Nitroarginine Methyl Ester; Nitric Oxide; omega-N-Methylarginine; Substrate Specificity; Urea | 2014 |
Possible role of nitric oxide (NO) in the regulation of gender related differences in stress induced anxiogenesis in rats.
Topics: Androstenedione; Animals; Anxiety; Arginine; Behavior, Animal; Brain; Enzyme Inhibitors; Female; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Wistar; Sex Factors; Stress, Physiological | 2014 |
ADMA, homocysteine and redox status improvement affected by 7-nitroindazole in spontaneously hypertensive rats.
Topics: Animals; Aorta; Arginine; Biomarkers; Disease Models, Animal; Enzyme Inhibitors; Heart Ventricles; Homocysteine; Hypertension; Indazoles; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Oxidation-Reduction; Rats, Inbred SHR | 2018 |
The protective effects of polysaccharide extract from Xin-Ji-Er-Kang formula on Ang II-induced HUVECs injury, L-NAME-induced hypertension and cardiovascular remodeling in mice.
Topics: Angiotensin II; Animals; Aorta; Arginine; Blood Pressure; Cytokines; Drug Evaluation, Preclinical; Drugs, Chinese Herbal; Endothelial Cells; Endothelium, Vascular; Human Umbilical Vein Endothelial Cells; Humans; Hypertension; Inflammation; Male; Malondialdehyde; Mice; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type III; Oxidative Stress; Phytotherapy; Superoxide Dismutase; Vascular Remodeling | 2019 |
The investigation of antioxidant and anti-inflammatory potentials of apitherapeutic agents on heart tissues in nitric oxide synthase inhibited rats via Nω-nitro-L-arginine methyl ester.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Arginine; Aryldialkylphosphatase; Blood Pressure; Caffeic Acids; Free Radical Scavengers; Male; Myocardium; NF-kappa B; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Oxidants; Oxidative Stress; Phenylethyl Alcohol; Pollen; Propolis; Rats; Rats, Sprague-Dawley | 2021 |