Compounds > n,n-dimethylarginine
Page last updated: 2024-09-03

n,n-dimethylarginine and mocetinostat

n,n-dimethylarginine has been researched along with mocetinostat in 17 studies

Compound Research Comparison

Studies
(n,n-dimethylarginine)		Trials
(n,n-dimethylarginine)		Recent Studies (post-2010)
(n,n-dimethylarginine)		Studies
(mocetinostat)		Trials
(mocetinostat)		Recent Studies (post-2010) (mocetinostat)
2,2162281,22121,7353908,606

Protein Interaction Comparison

ProteinTaxonomyn,n-dimethylarginine (IC50)mocetinostat (IC50)
Histone deacetylase 3Homo sapiens (human)0.7851
Nuclear receptor corepressor 1Homo sapiens (human)0.022
Cytochrome P450 3A4Homo sapiens (human)0.57
Cytochrome P450 2D6Homo sapiens (human)0.102
Cytochrome P450 2C19Homo sapiens (human)0.102
Histone deacetylase 4Homo sapiens (human)0.5717
Histone deacetylase 1Homo sapiens (human)0.3433
Histone deacetylase 7Homo sapiens (human)0.6725
Histone deacetylase 2Homo sapiens (human)0.3537
Histone deacetylase 11 Homo sapiens (human)0.6386
Histone deacetylase 8Homo sapiens (human)0.6725
Histone deacetylase 6Homo sapiens (human)0.5717
Histone deacetylase 5Homo sapiens (human)0.6725
Nuclear receptor corepressor 2Homo sapiens (human)0.045

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (23.53)29.6817
2010's13 (76.47)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Grdić, M; Huber, K; Maurer, G; Niessner, A; Penka, M; Richter, B; Simeon-Rudolf, V; Steiner, S; Strasser, B; Wojta, J; Ziegler, S; Zorn, G1
Conci, E; Cooke, JP; Haubner, BJ; Metzler, B; Pachinger, O; Schwaighofer, J; Stocker, EM; Stühlinger, MC; Tsao, PS1
Abdel Hamid, SG; El-Mesallamy, HO; Gad, MZ1
Bode-Böger, SM; Goette, A; Jentsch-Ullrich, K; Lendeckel, U; Martens-Lobenhoffer, J; Scalera, F; Wolfram, O1
Barbaros, B; Filiz, B; Gonca, O; Halil, Y; Nihal, S; Nurten, T; Ozgür, A1
Karu, I; Pruunsild, C; Starkopf, J; Taal, G; Zilmer, K; Zilmer, M1
Atzler, D; Baldus, S; Blankenberg, S; Böger, RH; D'Alecy, LG; Ehmke, H; Gadegbeku, CA; Hellwinkel, O; Kielstein, JT; Klinke, A; Kubala, L; Lau, D; Lund, N; Maas, R; Meinertz, T; Pekarova, M; Schmidt-Haupt, R; Schwedhelm, E; Slocum, JL; Sydow, K; Tsikas, D; von Leitner, EC; Willems, S1
Bouras, G; Deftereos, S1
Bekpinar, S; Develi-Is, S; Gurdol, F; Kusku-Kiraz, Z; Unlucerci, Y; Uysal, M1
Ali, OA; Chapman, M; Chirkov, YY; Heresztyn, T; Horowitz, JD; Mundisugih, J; Nguyen, TH1
Bekpinar, S; Gurdol, F; Unlucerci, Y; Uysal, M1
Bal, F; Bekpinar, S; Gurdol, F; Kusku-Kiraz, Z; Önder, S; Unlucerci, Y; Uysal, M1
Burma, O; Ilhan, N; Ozguler, IM; Sahna, E; Uysal, A1
Faldynova, L; Karpisek, M; Kovarova, P; Kukla, P; Kusnierova, P; Pleva, L; Plevova, P; Zapletalova, J1
Enko, D; März, W; Meinitzer, A; Pilz, S; Tomaschitz, A; Zelzer, S1
Fülöp, P; Harangi, M; Katkó, M; Lőrincz, H; Paragh, G; Seres, I; Szentpéteri, A; Varga, VE; Zsíros, N1
Lu, XY; Sui, GG; Sun, ZL; Xiao, HB1

Trials

1 trial(s) available for n,n-dimethylarginine and mocetinostat

ArticleYear
The effects of G-CSF-induced mobilization of progenitor cells are limited by ADMA.
    International journal of cardiology, 2010, Sep-03, Volume: 143, Issue:3

    Topics: Aged; Aged, 80 and over; Angina Pectoris; Antioxidants; Arginine; Cells, Cultured; Chromans; Coronary Disease; Endothelial Cells; Female; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Mobilization; Hematopoietic Stem Cells; Humans; Leukocytosis; Male; Middle Aged; Oxidative Stress; Peroxidase; Umbilical Veins

2010

Other Studies

16 other study(ies) available for n,n-dimethylarginine and mocetinostat

ArticleYear
Endurance training reduces circulating asymmetric dimethylarginine and myeloperoxidase levels in persons at risk of coronary events.
    Thrombosis and haemostasis, 2005, Volume: 94, Issue:6

    Topics: Adult; Aged; Arginine; Cardiovascular Diseases; Cyclic GMP; Exercise; Female; Humans; Male; Middle Aged; Peroxidase; Risk Factors

2005
Asymmetric dimethyl L-arginine (ADMA) is a critical regulator of myocardial reperfusion injury.
    Cardiovascular research, 2007, Jul-15, Volume: 75, Issue:2

    Topics: Amidohydrolases; Animals; Arginine; Blotting, Western; Endothelium, Vascular; Immunohistochemistry; Mice; Mice, Inbred C57BL; Mice, Transgenic; Myocardial Ischemia; Myocardial Reperfusion Injury; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Peroxidase

2007
Oxidative stress and asymmetric dimethylarginine are associated with cardiovascular complications in hemodialysis patients: improvements by L-arginine intake.
    Kidney & blood pressure research, 2008, Volume: 31, Issue:3

    Topics: Aged; Arginine; Cardiovascular Diseases; Case-Control Studies; Homocysteine; Humans; Kidney Failure, Chronic; Male; Malondialdehyde; Middle Aged; Oxidative Stress; Peroxidase; Renal Dialysis; Risk Factors

2008
Role of neutrophils in arginine-asymmetric dimethylarginine pathway subsequent to endotoxemia.
    Annals of the New York Academy of Sciences, 2009, Volume: 1173 Suppl 1

    Topics: Animals; Arginine; Disease Models, Animal; Endotoxemia; Guinea Pigs; Lipopolysaccharides; Liver; Male; Neutrophils; Peroxidase; Tyrosine

2009
Inflammatory/oxidative stress during the first week after different types of cardiac surgery.
    Scandinavian cardiovascular journal : SCJ, 2010, Volume: 44, Issue:2

    Topics: Aged; Arginine; Biomarkers; C-Reactive Protein; Cardiac Surgical Procedures; Cardiopulmonary Bypass; Coronary Artery Bypass; Female; Heart Valve Prosthesis Implantation; Homocysteine; Humans; Inflammation; Inflammation Mediators; Interleukin-6; Male; Middle Aged; Oxidative Stress; Peroxidase; Time Factors; Treatment Outcome

2010
Pathogenic cycle between the endogenous nitric oxide synthase inhibitor asymmetrical dimethylarginine and the leukocyte-derived hemoprotein myeloperoxidase.
    Circulation, 2011, Dec-13, Volume: 124, Issue:24

    Topics: Amidohydrolases; Animals; Arginine; Cardiovascular Diseases; Dose-Response Relationship, Drug; Female; HL-60 Cells; Humans; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Models, Animal; Neutrophils; Nitric Oxide; Nitric Oxide Synthase Type III; Peroxidase; Signal Transduction; Superoxides

2011
Editorial (hot topic: cardiovascular disease biomarkers: from tradition to modernity).
    Current topics in medicinal chemistry, 2013, Volume: 13, Issue:2

    Topics: Adiponectin; Arginine; Biomarkers; Cardiovascular Diseases; Cystatin C; Endothelins; Glycopeptides; Humans; MicroRNAs; Natriuretic Peptide, Brain; Peptide Fragments; Peroxidase; Predictive Value of Tests; Troponin

2013
Modulation of arginine and asymmetric dimethylarginine concentrations in liver and plasma by exogenous hydrogen sulfide in LPS-induced endotoxemia.
    Canadian journal of physiology and pharmacology, 2013, Volume: 91, Issue:12

    Topics: Alanine Transaminase; Amidohydrolases; Animals; Arginase; Arginine; Aspartate Aminotransferases; Endotoxemia; Hydrogen Sulfide; Hypoxia-Inducible Factor 1, alpha Subunit; Lipopolysaccharides; Liver; Male; Peroxidase; Rats; Rats, Wistar

2013
Interactions between inflammatory activation and endothelial dysfunction selectively modulate valve disease progression in patients with bicuspid aortic valve.
    Heart (British Cardiac Society), 2014, Volume: 100, Issue:10

    Topics: Aorta; Aortic Valve; Arginine; Bicuspid Aortic Valve Disease; Biomarkers; Disease Progression; Echocardiography; Endothelium, Vascular; Female; Follow-Up Studies; Heart Valve Diseases; Humans; Inflammation; Magnetic Resonance Imaging, Cine; Male; Middle Aged; Nitric Oxide Synthase; Peroxidase; Prognosis; Retrospective Studies; Severity of Illness Index; Vasodilation

2014
Propargylglycine aggravates liver damage in LPS-treated rats: Possible relation of nitrosative stress with the inhibition of H2S formation.
    Pharmacological reports : PR, 2014, Volume: 66, Issue:5

    Topics: Alkynes; Amidohydrolases; Animals; Arginine; Aspartate Aminotransferases; Chromatography, High Pressure Liquid; Cystathionine gamma-Lyase; Endotoxemia; Glutathione; Glycine; Hydrogen Sulfide; Lipopolysaccharides; Liver Diseases; Male; Peroxidase; Rats; Rats, Wistar; Stress, Physiological; Tyrosine

2014
Antidiabetic drug metformin is effective on the metabolism of asymmetric dimethylarginine in experimental liver injury.
    Diabetes research and clinical practice, 2014, Volume: 106, Issue:2

    Topics: Alanine Transaminase; Amidohydrolases; Animals; Arginine; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Galactosamine; Glutathione; Hypoglycemic Agents; Lipopolysaccharides; Male; Metformin; Peroxidase; Protective Agents; Rats; Rats, Sprague-Dawley

2014
Effects of apocynin, an NADPH oxidase inhibitor, on levels of ADMA, MPO, iNOS and TLR4 induced by myocardial ischemia reperfusion.
    Perfusion, 2015, Volume: 30, Issue:6

    Topics: Acetophenones; Animals; Arginine; Male; Myocardial Reperfusion Injury; Myocardium; NADPH Oxidases; Nitric Oxide Synthase Type II; Peroxidase; Rats; Rats, Sprague-Dawley; Toll-Like Receptor 4

2015
Increased levels of MMP-3, MMP-9 and MPO represent predictors of in-stent restenosis, while increased levels of ADMA, LCAT, ApoE and ApoD predict bare metal stent patency.
    Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia, 2015, Volume: 159, Issue:4

    Topics: Aged; Apolipoproteins D; Apolipoproteins E; Arginine; Biomarkers; Case-Control Studies; Coronary Restenosis; Female; Graft Occlusion, Vascular; Humans; Lipoprotein(a); Male; Matrix Metalloproteinase 3; Matrix Metalloproteinase 9; Middle Aged; Percutaneous Coronary Intervention; Peroxidase; Phosphatidylcholine-Sterol O-Acyltransferase; Stents; Vascular Patency

2015
Myeloperoxidase, asymmetric dimethyl-arginine and the renin-angiotensin-aldosterone-system in cardiovascular risk patients: Cross-sectional findings from the Ludwigshafen Risk and Cardiovascular Health (LURIC) study.
    Clinical biochemistry, 2017, Volume: 50, Issue:13-14

    Topics: Aged; Aldosterone; Arginine; Austria; Biomarkers; Cardiovascular Diseases; Cohort Studies; Coronary Angiography; Cross-Sectional Studies; Female; Follow-Up Studies; Germany; Glutathione Peroxidase; Glutathione Peroxidase GPX1; Humans; Male; Middle Aged; Mortality; Peroxidase; Predictive Value of Tests; Prevalence; Prospective Studies; Renin-Angiotensin System; Risk Factors

2017
Paraoxonase-1 and myeloperoxidase correlate with vascular biomarkers in overweight patients with newly diagnosed untreated hyperlipidaemia.
    VASA. Zeitschrift fur Gefasskrankheiten, 2017, Volume: 46, Issue:5

    Topics: Adult; Aged; Arginine; Aryldialkylphosphatase; Biomarkers; C-Reactive Protein; Case-Control Studies; CD40 Ligand; Female; Humans; Hyperlipidemias; Intercellular Adhesion Molecule-1; Lipoproteins, LDL; Male; Middle Aged; Overweight; Peroxidase; Predictive Value of Tests; Vascular Cell Adhesion Molecule-1

2017
Elevated Levels of ADMA Are Associated with Lower DDAH2 and Higher PRMT1 in LPS-Induced Endometritis Rats.
    Inflammation, 2018, Volume: 41, Issue:1

    Topics: Amidohydrolases; Animals; Arginine; Dinoprost; Disease Models, Animal; Down-Regulation; Endometriosis; Female; Interleukin-6; Lipopolysaccharides; Peroxidase; Protein-Arginine N-Methyltransferases; Rats, Wistar; Reactive Oxygen Species; Tumor Necrosis Factor-alpha; Up-Regulation; Uterus

2018