Page last updated: 2024-09-03

n,n-dimethylarginine and lysine

n,n-dimethylarginine has been researched along with lysine in 12 studies

Compound Research Comparison

Studies (n,n-dimethylarginine)	Trials (n,n-dimethylarginine)	Recent Studies (post-2010) (n,n-dimethylarginine)	Studies (lysine)	Trials (lysine)	Recent Studies (post-2010) (lysine)
2,216	228	1,221	37,449	622	11,213

Protein Interaction Comparison

Protein	Taxonomy	n,n-dimethylarginine (IC50)	lysine (IC50)
Cationic amino acid transporter 3	Homo sapiens (human)		158

Research

Studies (12)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	1 (8.33)	18.2507
2000's	2 (16.67)	29.6817
2010's	9 (75.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Fast, W; Hong, L	1
Lazarides, E; Lin, JM; Wang, C	1
Brennan, DM; Cho, L; Hazen, SL; Tang, WH; Wang, Z	1
Bai, YP; Chen, L; Chen, XP; Guo, YJ; Li, L; Li, YJ; Sun, J; Xia, J; Yang, TL; Zhang, GG	1
Fung, HL; Mohan, S	1
Bleie, O; Borgeraas, H; Løland, KH; Nordrehaug, JE; Nygård, O; Strand, E; Svardal, A; Ueland, PM	1
Akcali, KC; Ayaloglu-Butun, F; Demirel-Yilmaz, E; Han, S; Uludag, MO; Usanmaz, SE	1
Jing, Z; Kuang, L; Liu, N; Yang, J	1
He, J; Jing, Z; Kuang, L; Liu, N; Sun, Z; Wang, Y; Yang, J	1
Singh, SA; Srinivasan, K; Venkatesh, R	1
Bollenbach, A; Brunner, G; Hanff, E; Tsikas, D	1
Auge, D; Chafai, A; Fromm, MF; Gessner, A; Maas, R; Mieth, M; Müller, F	1

Trials

1 trial(s) available for n,n-dimethylarginine and lysine

Article	Year
The association between progression of atherosclerosis and the methylated amino acids asymmetric dimethylarginine and trimethyllysine. PloS one, 2013, Volume: 8, Issue:5 Topics: Adenosine; Aged; Arginine; Coronary Angiography; Coronary Artery Disease; Disease Progression; Ethionine; Female; Folic Acid; Follow-Up Studies; Humans; Lysine; Male; Methylation; Middle Aged; Treatment Outcome; Vitamin B 12; Vitamin B 6; Vitamin B Complex	2013

Article

Year

The association between progression of atherosclerosis and the methylated amino acids asymmetric dimethylarginine and trimethyllysine.

PloS one, 2013, Volume: 8, Issue:5

Topics: Adenosine; Aged; Arginine; Coronary Angiography; Coronary Artery Disease; Disease Progression; Ethionine; Female; Folic Acid; Follow-Up Studies; Humans; Lysine; Male; Methylation; Middle Aged; Treatment Outcome; Vitamin B 12; Vitamin B 6; Vitamin B Complex

2013

Other Studies

11 other study(ies) available for n,n-dimethylarginine and lysine

Article	Year
Inhibition of human dimethylarginine dimethylaminohydrolase-1 by S-nitroso-L-homocysteine and hydrogen peroxide. Analysis, quantification, and implications for hyperhomocysteinemia. The Journal of biological chemistry, 2007, Nov-30, Volume: 282, Issue:48 Topics: Amidohydrolases; Amino Acid Sequence; Animals; Binding Sites; Cloning, Molecular; Cysteine; Dose-Response Relationship, Drug; Drug Design; Homocysteine; Humans; Hydrogen Peroxide; Hyperhomocysteinemia; Kinetics; Molecular Sequence Data; Oxidation-Reduction; Sequence Homology, Amino Acid; Substrate Specificity	2007
Methylations of 70,000-Da heat shock proteins in 3T3 cells: alterations by arsenite treatment, by different stages of growth and by virus transformation. Archives of biochemistry and biophysics, 1992, Aug-15, Volume: 297, Issue:1 Topics: 3T3 Cells; Animals; Arginine; Arsenic; Arsenites; Avian Sarcoma Viruses; Cell Division; Cell Transformation, Viral; Chromatography, Ion Exchange; Electrophoresis, Gel, Two-Dimensional; Heat-Shock Proteins; Lysine; Methionine; Methylation; Mice; Molecular Weight; omega-N-Methylarginine	1992
Targeted metabolomic evaluation of arginine methylation and cardiovascular risks: potential mechanisms beyond nitric oxide synthase inhibition. Arteriosclerosis, thrombosis, and vascular biology, 2009, Volume: 29, Issue:9 Topics: Aged; Arginine; Biomarkers; C-Reactive Protein; Cardiovascular Diseases; Chromatography, High Pressure Liquid; Citrulline; Coronary Artery Disease; Creatinine; Female; Humans; Lysine; Male; Metabolomics; Methylation; Middle Aged; Nitric Oxide Synthase; Odds Ratio; omega-N-Methylarginine; Ornithine; Prognosis; Prospective Studies; Protein Processing, Post-Translational; Risk Assessment; Risk Factors; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Time Factors	2009
The ALDH2 Glu504Lys polymorphism is associated with coronary artery disease in Han Chinese: Relation with endothelial ADMA levels. Atherosclerosis, 2010, Volume: 211, Issue:2 Topics: Aged; Aldehyde Dehydrogenase; Aldehyde Dehydrogenase, Mitochondrial; Arginine; China; Coronary Artery Disease; Endothelium, Vascular; Female; Glutamic Acid; Humans; Lysine; Male; Middle Aged; Odds Ratio; Polymorphism, Genetic; Risk Factors	2010
Mechanism of cellular oxidation stress induced by asymmetric dimethylarginine. International journal of molecular sciences, 2012, Volume: 13, Issue:6 Topics: Arginine; Biopterins; Enzyme Inhibitors; Human Umbilical Vein Endothelial Cells; Humans; Lysine; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide Synthase Type III; Nitrites; Oxidative Stress	2012
Resveratrol affects histone 3 lysine 27 methylation of vessels and blood biomarkers in DOCA salt-induced hypertension. Molecular biology reports, 2015, Volume: 42, Issue:1 Topics: Animals; Antioxidants; Arginine; Biomarkers; Blood Pressure; Blood Vessels; Desoxycorticosterone Acetate; Endothelium, Vascular; Fluorescent Antibody Technique; Histones; Hydrogen Sulfide; Hypertension; Lysine; Male; Methylation; Nitrites; Rats, Wistar; Renal Artery; Resveratrol; Stilbenes; Systole; Vasodilation	2015
LC-MS/MS for the simultaneous determination of polar endogenous ADMA and CML in plasma and urine from diabetics. Bioanalysis, 2015, Volume: 7, Issue:10 Topics: Arginine; Chromatography, High Pressure Liquid; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Humans; Linear Models; Lysine; Retrospective Studies; Tandem Mass Spectrometry	2015
ADMA: a specific biomarker for pathologic progress in diabetic microvascular complications? Biomarkers in medicine, 2016, Volume: 10, Issue:4 Topics: Adult; Aged; Area Under Curve; Arginine; Biomarkers; Case-Control Studies; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glucose Tolerance Test; Glycated Hemoglobin; Humans; Logistic Models; Lysine; Male; Middle Aged; Odds Ratio; Prediabetic State; ROC Curve; Tandem Mass Spectrometry	2016
Effect of arginine:lysine and glycine:methionine intake ratios on dyslipidemia and selected biomarkers implicated in cardiovascular disease: A study with hypercholesterolemic rats. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2017, Volume: 91 Topics: Administration, Oral; Amino Acids; Animals; Arginine; Biomarkers; Body Weight; Cardiovascular Diseases; Dyslipidemias; Glycine; Homocysteine; Hypercholesterolemia; Lipids; Liver; Lysine; Male; Methionine; Nitric Oxide; Organ Size; Rats, Wistar	2017
Asymmetric dimethylation and citrullination of proteinic arginine and homoarginine synthesis in human Helicobacter pylori infection. Amino acids, 2019, Volume: 51, Issue:6 Topics: Adult; Aged; Aged, 80 and over; Arginine; Citrullination; Citrulline; Female; Gas Chromatography-Mass Spectrometry; Helicobacter Infections; Helicobacter pylori; Homoarginine; Humans; Lysine; Male; Methylation; Middle Aged; Nitric Oxide; Ornithine	2019
Establishment of reference values for the lysine acetylation marker N Amino acids, 2019, Volume: 51, Issue:9 Topics: Adolescent; Adult; Arginine; Biomarkers; Cardiovascular Diseases; Carnitine; Chromatography, Liquid; Citrulline; Creatinine; Female; Homoarginine; Humans; Lysine; Male; Middle Aged; Ornithine; Reference Values; Renal Insufficiency, Chronic; Tandem Mass Spectrometry; Young Adult	2019