Page last updated: 2024-09-03

n,n-dimethylarginine and losartan potassium

n,n-dimethylarginine has been researched along with losartan potassium in 11 studies

Compound Research Comparison

Studies
(n,n-dimethylarginine)
Trials
(n,n-dimethylarginine)
Recent Studies (post-2010)
(n,n-dimethylarginine)
Studies
(losartan potassium)
Trials
(losartan potassium)
Recent Studies (post-2010) (losartan potassium)
2,2162281,22124,3902,4935,408

Protein Interaction Comparison

ProteinTaxonomyn,n-dimethylarginine (IC50)losartan potassium (IC50)
Bile salt export pumpHomo sapiens (human)8.53
Type-1A angiotensin II receptor Rattus norvegicus (Norway rat)0.0082
Type-1B angiotensin II receptorRattus norvegicus (Norway rat)0.0049
Type-2 angiotensin II receptorRattus norvegicus (Norway rat)0.0082
5-hydroxytryptamine receptor 1AMus musculus (house mouse)0.0082
Type-1 angiotensin II receptorCavia porcellus (domestic guinea pig)0.018

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (45.45)29.6817
2010's6 (54.55)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Acchiardo, SR; Cates, TB; Kang, ES; Miles, DE; Tevlin, MT1
Bode-Böger, SM; Kielstein, JT; Martens-Lobenhoffer, J; Postel, SC; Scalera, F; Täger, M1
Desai, A; Warren, JS; Zhao, Y1
Calò, LA; Davis, PA1
Surdacki, A; Wieczorek-Surdacka, E1
Fujiwara, N; Hikichi, Y; Kawagoe, Y; Nakamura, T; Node, K; Sato, E; Ueda, Y1
Bode-Böger, SM; Ehrenreich, H; Hecker, H; Joumaah, M; Kielstein, JT; Li, N; Lichtinghagen, R; Martens-Lobenhoffer, J; Weissenborn, K; Worthmann, H1
Ando, A; Kawashima, M; Mikami, H; Naito, T; Nishimura, H; Nitta, K; Niwayama, J; Ogawa, T; Sanaka, T; Segawa, K; Soga, A; Teramoto, A; Yamatani, K; Yoshikura, T1
Liu, B; Niu, K; Shi, Y; Wang, L; Wang, T; Zhang, Y1
Abe, T; Ando, R; Fukami, K; Ito, S; Kaida, Y; Kimoto, M; Nakayama, Y; Saigusa, D; Sugiyama, M; Taguchi, K; Ueda, S; Yamagishi, SI; Yano, J; Yokoro, M1
de Oliveira-Fonoff, AM; Fernandes, F; Fonseca, KCB; Jordão, MR; Mady, C; Pessoa, FG; Ramires, FJA; Salemi, VMC1

Trials

2 trial(s) available for n,n-dimethylarginine and losartan potassium

ArticleYear
Renovascular protective effects of erythropoietin in patients with chronic kidney disease.
    Internal medicine (Tokyo, Japan), 2011, Volume: 50, Issue:18

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Acute Kidney Injury; Aged; Arginine; Atherosclerosis; Biomarkers; Cardiovascular System; Carotid Intima-Media Thickness; Deoxyguanosine; Dose-Response Relationship, Drug; Erythropoietin; Fatty Acid-Binding Proteins; Female; Glomerular Filtration Rate; Hemoglobins; Humans; Kidney; Kidney Failure, Chronic; Male; Middle Aged; Natriuretic Peptide, Brain; Oxidative Stress; Prospective Studies; Recombinant Proteins; Treatment Outcome

2011
Asymmetric dimethylarginine in response to recombinant tissue-type plasminogen activator and erythropoietin in acute stroke.
    Stroke, 2013, Volume: 44, Issue:8

    Topics: Acute Disease; Aged; Aged, 80 and over; Arginine; Double-Blind Method; Drug Therapy, Combination; Erythropoietin; Female; Humans; Male; Middle Aged; Severity of Illness Index; Stroke; Thrombolytic Therapy; Tissue Plasminogen Activator; Treatment Outcome

2013

Other Studies

9 other study(ies) available for n,n-dimethylarginine and losartan potassium

ArticleYear
Reversible sequestration of nitric oxide by hemoglobin during hemodialysis in end-stage renal disease.
    The American journal of the medical sciences, 2001, Volume: 321, Issue:2

    Topics: Anemia; Arginine; Erythropoietin; Hematocrit; Hemoglobins; Humans; Hypotension; Kidney Failure, Chronic; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Renal Dialysis; Skin Temperature

2001
Erythropoietin increases asymmetric dimethylarginine in endothelial cells: role of dimethylarginine dimethylaminohydrolase.
    Journal of the American Society of Nephrology : JASN, 2005, Volume: 16, Issue:4

    Topics: Amidohydrolases; Antioxidants; Arginine; Cells, Cultured; Darbepoetin alfa; Endothelial Cells; Erythropoietin; Humans; Intracellular Membranes; Nitric Oxide; Oxidative Stress; Pyrrolidines; Recombinant Proteins; Thiocarbamates

2005
Human recombinant erythropoietin augments serum asymmetric dimethylarginine concentrations but does not compromise nitric oxide generation in mice.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2008, Volume: 23, Issue:5

    Topics: Amidohydrolases; Animals; Arginine; Base Sequence; Cells, Cultured; DNA Primers; Endothelial Cells; Epoetin Alfa; Erythropoietin; Humans; Kidney; Kidney Failure, Chronic; Liver; Male; Mice; Mice, Inbred BALB C; Nitric Oxide; Nitric Oxide Synthase Type II; Recombinant Proteins; Up-Regulation; Vascular Diseases

2008
EPO induces rise in serum ADMA but does not prevent the increase in NO release: the likely involvement of HO-1.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2008, Volume: 23, Issue:9

    Topics: Animals; Apoptosis; Arginine; Endothelium, Vascular; Epoetin Alfa; Erythropoietin; Heme Oxygenase-1; Humans; Kidney Failure, Chronic; Nitric Oxide; Nitric Oxide Synthase; Recombinant Proteins; Renal Dialysis

2008
Endothelial and red blood cell turnover rate--factors possibly affecting circulating ADMA levels?
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2009, Volume: 24, Issue:4

    Topics: Amidohydrolases; Arginine; Endothelial Cells; Erythrocytes; Erythropoietin; Humans

2009
Modulation of circulating endothelial progenitor cells by erythropoiesis-stimulating agents in patients with chronic kidney disease stage G5 and 5D
.
    Clinical nephrology, 2016, Volume: 86 (2016), Issue:11

    Topics: Adult; Arginine; Biomarkers; C-Reactive Protein; Cell Count; Darbepoetin alfa; Endothelial Progenitor Cells; Erythropoietin; Female; Hematinics; Humans; Kidney Failure, Chronic; Male; Matrix Metalloproteinase 2; Middle Aged; Prospective Studies; Recombinant Proteins; Renal Dialysis; Vascular Endothelial Growth Factor A

2016
Association of the -449GC and -1151AC polymorphisms in the DDAH2 gene with asymmetric dimethylarginine and erythropoietin resistance in Chinese patients on maintenance hemodialysis.
    Clinical and experimental pharmacology & physiology, 2017, Volume: 44, Issue:9

    Topics: Alleles; Amidohydrolases; Arginine; Asian People; Erythropoietin; Female; Genotype; Humans; Male; Middle Aged; Polymorphism, Single Nucleotide; Renal Dialysis

2017
Asymmetric Dimethylarginine Contributes to the Impaired Response to Erythropoietin in CKD-Anemia.
    Journal of the American Society of Nephrology : JASN, 2017, Volume: 28, Issue:9

    Topics: Aged; Amidohydrolases; Anemia; Animals; Arginine; Cytokines; Drug Resistance; Erythrocyte Indices; Erythrocytes; Erythropoietin; Female; Gene Expression; Hematinics; Hematocrit; Hemoglobins; Humans; Male; Mice; Middle Aged; Muscle Proteins; Nephrectomy; Plasma; Receptors, Erythropoietin; Renal Insufficiency, Chronic

2017
Erythropoietin reduces collagen deposition after myocardial infarction but does not improve cardiac function.
    Canadian journal of physiology and pharmacology, 2018, Volume: 96, Issue:6

    Topics: Animals; Apoptosis; Arginine; Collagen; Diastole; Erythropoietin; Glutathione; Heart; Hematocrit; Hemoglobins; Male; Myocardial Infarction; Myocardium; Oxidative Stress; Rats

2018