Page last updated: 2024-09-03

n,n-dimethylarginine and febuxostat

n,n-dimethylarginine has been researched along with febuxostat in 2 studies

Compound Research Comparison

Studies
(n,n-dimethylarginine)
Trials
(n,n-dimethylarginine)
Recent Studies (post-2010)
(n,n-dimethylarginine)
Studies
(febuxostat)
Trials
(febuxostat)
Recent Studies (post-2010) (febuxostat)
2,2162281,221818133710

Protein Interaction Comparison

ProteinTaxonomyn,n-dimethylarginine (IC50)febuxostat (IC50)
Multidrug resistance-associated protein 4Homo sapiens (human)1.9
AlbuminHomo sapiens (human)0.0013
Xanthine dehydrogenase/oxidase [Includes: Xanthine dehydrogenase Rattus norvegicus (Norway rat)0.004
Xanthine dehydrogenase/oxidaseHomo sapiens (human)0.0164
Nuclear receptor ROR-gammaMus musculus (house mouse)0.025
Xanthine dehydrogenase/oxidaseBos taurus (cattle)0.0166
Histamine H3 receptorCavia porcellus (domestic guinea pig)0.03
Broad substrate specificity ATP-binding cassette transporter ABCG2Homo sapiens (human)0.027

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (50.00)24.3611
2020's1 (50.00)2.80

Authors

AuthorsStudies
Alshahawey, M; Elsaid, TW; Sabri, NA; Shahin, SM1
Doi, Y; Fukae, S; Ikeda, S; Kawano, H; Koga, S; Maemura, K; Minami, T; Nakata, T; Tsuneto, A; Yonekura, T1

Trials

2 trial(s) available for n,n-dimethylarginine and febuxostat

ArticleYear
Effect of Febuxostat on the Endothelial Dysfunction in Hemodialysis Patients: A Randomized, Placebo-Controlled, Double-Blinded Study.
    American journal of nephrology, 2017, Volume: 45, Issue:5

    Topics: Administration, Oral; Adult; Alanine Transaminase; Arginine; Aspartate Aminotransferases; C-Reactive Protein; Cardiovascular Diseases; Double-Blind Method; Endothelium, Vascular; Enzyme Inhibitors; Febuxostat; Female; Humans; Incidence; Kidney Failure, Chronic; Male; Middle Aged; Pancytopenia; Placebos; Prospective Studies; Renal Dialysis; Risk Factors; Treatment Outcome; Uric Acid; Xanthine Oxidase

2017
Randomized, Open-Label, Cross-Over Comparison of the Effects of Benzbromarone and Febuxostat on Endothelial Function in Patients with Hyperuricemia.
    International heart journal, 2020, Sep-29, Volume: 61, Issue:5

    Topics: Adiponectin; Aged; Arginine; Benzbromarone; Cross-Over Studies; Endothelium, Vascular; Febuxostat; Female; Gout Suppressants; Humans; Hyperemia; Hyperuricemia; Male; Middle Aged; Organic Anion Transporters; Organic Cation Transport Proteins; Treatment Outcome; Uric Acid; Uricosuric Agents; Xanthine Oxidase

2020