Page last updated: 2024-09-03

n,n-dimethylarginine and d-alpha tocopherol

n,n-dimethylarginine has been researched along with d-alpha tocopherol in 13 studies

Compound Research Comparison

Studies
(n,n-dimethylarginine)
Trials
(n,n-dimethylarginine)
Recent Studies (post-2010)
(n,n-dimethylarginine)
Studies
(d-alpha tocopherol)
Trials
(d-alpha tocopherol)
Recent Studies (post-2010) (d-alpha tocopherol)
2,2162281,22132,1982,9037,258

Protein Interaction Comparison

ProteinTaxonomyn,n-dimethylarginine (IC50)d-alpha tocopherol (IC50)
Glutathione S-transferase PHomo sapiens (human)0.5

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (7.69)18.2507
2000's8 (61.54)29.6817
2010's4 (30.77)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Li, NS; Li, YJ; Liu, GZ; Xiong, Y; Yu, XJ1
Abdulhayoglu, E; Barbato, D; Bustami, R; D'Alecy, LG; Desai, A; Handelman, GJ; Novak, JE; Rajagopalan, S; Saran, R; Warren, JS; Weitzel, W1
Bae, SW; Choi, BY; Choi, YH; Lee, SH; Lee, YS; Pachinger, O; Park, HK; Park, JE; Stühlinger, MC; Yoo, HS; Yu, KH1
Fukuda, S; Fukuoka, K; Kihara, T; Makino, H; Morimoto, H; Nakao, K; Sarai, A; Wada, J; Yano, A1
Deng, HW; Deng, S; Jia, SJ; Li, D; Li, YJ; Wang, L; Xia, K; Yang, ZC; Zhang, XH; Zhang, Z1
Hu, CP; Huang, H; Jia, SJ; Jiang, DJ; Jiang, JL; Li, YJ; Tan, B1
Kiefte-de Jong, JC; Nanayakkara, PW; Olthof, MR; Smulders, YM; Stehouwer, CD; Teerlink, T; ter Wee, PM; Twisk, JW; van Guldener, C; van Ittersum, FJ1
Ciabattoni, G; Cuccurullo, C; Davì, G; Ferroni, P; Guagnano, MT; Manigrasso, MR; Paoletti, V; Pescara, L; Santilli, F1
Chen, XP; Li, YJ; Wang, KS; Wu, Y; Xiang, YY; Yang, ZC; Zou, XQ1
Evans, A; Gey, KF; Gilchrist, SE; McKinley, MC; O'Doherty, MG; Skidmore, PM; Woodside, JV; Yarnell, JW; Young, IS1
Antoniades, C; Bouras, G; Hatzis, G; Marinou, K; Miliou, A; Papageorgiou, N; Stefanadi, E; Stefanadis, C; Tousoulis, D; Tsioufis, C1
Chan, CC; Huang, YT; Lee, FY; Lee, SD; Lee, TY; Lin, HC; Yang, YY; Yeh, YC1
Aydogdu, N; Cakir, E; Erbas, H; Türksever, A1

Trials

4 trial(s) available for n,n-dimethylarginine and d-alpha tocopherol

ArticleYear
Impact of vitamin E on plasma asymmetric dimethylarginine (ADMA) in chronic kidney disease (CKD): a pilot study.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2003, Volume: 18, Issue:11

    Topics: Adult; Aged; alpha-Tocopherol; Antioxidants; Arginine; Chronic Disease; Female; Humans; Kidney; Kidney Diseases; Male; Middle Aged; Oxidative Stress; Pilot Projects

2003
Long-term use of vitamin E-coated polysulfone membrane reduces oxidative stress markers in haemodialysis patients.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2005, Volume: 20, Issue:12

    Topics: Adult; Aged; Aged, 80 and over; Antioxidants; Arginine; Biomarkers; Coated Materials, Biocompatible; Female; Follow-Up Studies; Humans; Kidney Failure, Chronic; Lipoproteins, LDL; Male; Membranes, Artificial; Middle Aged; Nitric Oxide Synthase; Oxidative Stress; Polymers; Prognosis; Renal Dialysis; Sulfones; Time Factors; Vitamin E

2005
Randomized placebo-controlled trial assessing a treatment strategy consisting of pravastatin, vitamin E, and homocysteine lowering on plasma asymmetric dimethylarginine concentration in mild to moderate CKD.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2009, Volume: 53, Issue:1

    Topics: Adult; Aged; Anticholesteremic Agents; Arginine; Carotid Arteries; Chronic Disease; Creatinine; Double-Blind Method; Female; Folic Acid; Homocysteine; Humans; Kidney Diseases; Lipoproteins, LDL; Male; Middle Aged; Pravastatin; Vitamin B 12; Vitamin B 6; Vitamin E

2009
Effect of supplementation with B vitamins and antioxidants on levels of asymmetric dimethylarginine (ADMA) and C-reactive protein (CRP): a double-blind, randomised, factorial design, placebo-controlled trial.
    European journal of nutrition, 2010, Volume: 49, Issue:8

    Topics: Adult; Antioxidants; Arginine; Ascorbic Acid; beta Carotene; Biomarkers; Blood Pressure; C-Reactive Protein; Cardiovascular Diseases; Cholesterol; Dietary Supplements; Double-Blind Method; Homocysteine; Humans; Male; Middle Aged; Protective Agents; Triglycerides; Vitamin B Complex; Vitamin E

2010

Other Studies

9 other study(ies) available for n,n-dimethylarginine and d-alpha tocopherol

ArticleYear
Endogenous inhibitors of nitric oxide synthesis and lipid peroxidation in hyperlipidemic rabbits.
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1996, Volume: 17, Issue:2

    Topics: Animals; Aorta, Thoracic; Arginine; Hyperlipidemias; Lipid Peroxidation; Male; Malondialdehyde; Nitric Oxide; Rabbits; Vasodilation; Vitamin E

1996
Plasma asymmetric dimethylarginine concentrations in newly diagnosed patients with acute myocardial infarction or unstable angina pectoris during two weeks of medical treatment.
    The American journal of cardiology, 2005, Mar-15, Volume: 95, Issue:6

    Topics: Adult; Aged; alpha-Tocopherol; Angina, Unstable; Angioplasty, Balloon, Coronary; Arginine; C-Reactive Protein; Cardiovascular Agents; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Combined Modality Therapy; Coronary Angiography; Coronary Artery Disease; Enzyme Inhibitors; Female; Follow-Up Studies; Humans; Insulin; Lipoproteins, HDL; Male; Middle Aged; Myocardial Infarction; Statistics as Topic; Treatment Outcome; Triglycerides

2005
Asymmetric dimethylarginine reduced erythrocyte deformability in streptozotocin-induced diabetic rats.
    Microvascular research, 2007, Volume: 73, Issue:2

    Topics: Animals; Aorta, Thoracic; Arginine; Diabetes Mellitus, Experimental; Endothelium, Vascular; Erythrocyte Deformability; In Vitro Techniques; Male; Malondialdehyde; Nitric Oxide; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Vitamin E

2007
Taurine protects against low-density lipoprotein-induced endothelial dysfunction by the DDAH/ADMA pathway.
    Vascular pharmacology, 2007, Volume: 46, Issue:5

    Topics: Acetylcholine; Amidohydrolases; Animals; Arginine; Cardiovascular Agents; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Endothelial Cells; Endothelium, Vascular; Enzyme Activation; Humans; Lipoproteins, LDL; Male; Malondialdehyde; Nitric Oxide; Rats; Rats, Sprague-Dawley; Taurine; Time Factors; Tumor Necrosis Factor-alpha; Vasodilation; Vasodilator Agents; Vitamin E

2007
Determinants of platelet activation in hypertensives with microalbuminuria.
    Free radical biology & medicine, 2009, Apr-01, Volume: 46, Issue:7

    Topics: Aged; Albuminuria; Arginine; Biomarkers; Disease Progression; Endothelium; Female; Humans; Hypertension; Intercellular Adhesion Molecule-1; Lipid Peroxidation; Male; Middle Aged; Nitric Oxide; Oxidative Stress; P-Selectin; Platelet Activation; Prostaglandins A; Thromboxane B2; Vitamin E

2009
Asymmetric dimethylarginine impairs glucose utilization via ROS/TLR4 pathway in adipocytes: an effect prevented by vitamin E.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2009, Volume: 24, Issue:1-2

    Topics: 3T3-L1 Cells; Adipocytes; Animals; Arginine; Cell Line; Enzyme Inhibitors; Glucose; Glucose Transporter Type 4; Insulin Receptor Substrate Proteins; Mice; Nitric Oxide; Nitric Oxide Synthase; Reactive Oxygen Species; Signal Transduction; Toll-Like Receptor 4; Tumor Necrosis Factor-alpha; Vitamin E

2009
Methionine-induced homocysteinemia impairs endothelial function in hypertensives: the role of asymmetrical dimethylarginine and antioxidant vitamins.
    American journal of hypertension, 2011, Volume: 24, Issue:8

    Topics: Adult; Antioxidants; Arginine; Ascorbic Acid; Endothelium, Vascular; Female; Homocysteine; Humans; Hyperhomocysteinemia; Hypertension; Male; Methionine; Middle Aged; Vasodilation; Vitamin E

2011
Asymmetric dimethylarginine (ADMA) determines the improvement of hepatic endothelial dysfunction by vitamin E in cirrhotic rats.
    Liver international : official journal of the International Association for the Study of the Liver, 2012, Volume: 32, Issue:1

    Topics: Animals; Antioxidants; Arginine; Drug Synergism; Endothelial Cells; Enzyme Inhibitors; Hemodynamics; Hypertension, Portal; In Vitro Techniques; Lipid Peroxidation; Liver; Liver Cirrhosis, Experimental; Male; Nitric Oxide; Oxidative Stress; Perfusion; Rats; Rats, Sprague-Dawley; Vasoconstriction; Vitamin E

2012
Asymmetric dimethylarginine in experimental breast cancer; action of Vitamin C and E.
    JPMA. The Journal of the Pakistan Medical Association, 2015, Volume: 65, Issue:8

    Topics: Animals; Antioxidants; Arginase; Arginine; Ascorbic Acid; Female; Mammary Neoplasms, Experimental; Mice; Nitric Oxide; Nitric Oxide Synthase; Vitamin E

2015