n,n-dimethylarginine has been researched along with citrulline in 53 studies
| Studies (n,n-dimethylarginine) | Trials (n,n-dimethylarginine) | Recent Studies (post-2010) (n,n-dimethylarginine) | Studies (citrulline) | Trials (citrulline) | Recent Studies (post-2010) (citrulline) |
|---|---|---|---|---|---|
| 2,216 | 228 | 1,221 | 4,572 | 195 | 1,537 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (1.89) | 18.7374 |
| 1990's | 2 (3.77) | 18.2507 |
| 2000's | 10 (18.87) | 29.6817 |
| 2010's | 33 (62.26) | 24.3611 |
| 2020's | 7 (13.21) | 2.80 |
| Authors | Studies |
|---|---|
| Fast, W; Hu, S; Monzingo, AF; Robertus, JD; Schaller, TH; Wang, Y | 1 |
| Kimoto, M; Ogawa, T; Sasaoka, K | 1 |
| Brian, JE; Faraci, FM; Heistad, DD | 1 |
| Fickling, SA; MacAllister, RJ; Vallance, P; Whitley, GS | 1 |
| Bode-Böger, SM; Krug, O; Martens-Lobenhoffer, J | 1 |
| Chin-Dusting, J; Kaye, DM; Venardos, K; Zhang, WZ | 1 |
| Bellinghieri, G; De Luca, G; Di Giorgio, RM; Mallamace, A; Santoro, D; Savica, V | 1 |
| Sim, AS; Wang, J; Wang, XL; Wilcken, DE | 1 |
| Baylis, C; Tain, YL | 1 |
| Böger, RH; Freese, R; Jambrecina, A; Jung, D; Lukacs, Z; Maas, R; Schulze, F; Schwedhelm, E; Spickler, W | 1 |
| Espey, MG; Harvey-White, J; Jung, CS; Oldfield, EH; Pluta, RM; Seifert, V; Zimmermann, M | 1 |
| Blackwelder, WC; Hazen, SL; Kato, GJ; Machado, RF; Taylor, JG; Wang, Z | 1 |
| Brennan, DM; Cho, L; Hazen, SL; Tang, WH; Wang, Z | 1 |
| Lentz, SR; Murry, DJ; Rodionov, RN; Stevens, JW; Vaulman, SF | 1 |
| Baylis, C; Chen, GF; Moningka, NC; Sasser, JM; Wagner, L; Zharikov, S | 1 |
| Chiandetti, L; Di Gangi, IM; Giordano, G; Gucciardi, A; Moret, V; Naturale, M | 1 |
| Huang, LT; Lau, YT; Lin, CY; Lin, IC; Tain, YL | 1 |
| Hayashi, T; Ina, K; Maeda, M; Morishita, K; Morita, M; Ochiai, M; Watanabe, F | 1 |
| Jung, CS | 1 |
| Akalin, S; Akgul, EO; Alacam, H; Aydin, I; Cakir, E; Danisman, N; Deren, O; Dikmen, ZG; Dogan, P; Keskin, U; Kurt, YG; Polat, B; Yaman, H | 1 |
| Fung, HL; Mohan, S; Shin, S; Wu, CC | 1 |
| Chen, CC; Hsieh, CS; Hsu, CN; Huang, LT; Hung, JF; Tain, YL; Yu, HR | 1 |
| Dalton, RN; Davies, NA; Deutz, NE; Jalan, R; Mookerjee, RP; Revhaug, A; Rose, CF; Sen, S; Sharma, V; Ten Have, GA; Turner, C; van-Eijk, HM; Ytrebo, L | 1 |
| Ast, J; Bogdaski, P; Cielewicz, AR; Drozdowski, M; Jabecka, A; Pawlak-Lemaska, K; Pupek-Musialik, D | 1 |
| Chien, SJ; Hsu, CN; Huang, CF; Huang, LT; Lin, YJ; Tain, YL | 1 |
| Chien, SJ; Huang, CF; Huang, LT; Kuo, HC; Lin, KM; Lin, YJ; Tain, YL | 1 |
| Blackledge, M; Chisty, LT; Driscoll, PC; Kirkpatrick, J; Rasheed, M; Richter, C; Webb, MR | 1 |
| Ragina, NP; Rowland, MR; Sarkar, J; Senagore, AJ; Uyehara, CF | 1 |
| Drašković-Pavlović, B; Majstorović, I; Spasić, S; Tomić, A; Vučević, D; Žunić, G | 1 |
| Delafontaine, P; Egan, P; Fernandez, C; Giles, TD; Kandavar, R; Kim, C; Roffidal, LE; Sander, GE; Sukhanov, S; Velaga, S | 1 |
| He, GW; Liu, Z; Lun, LM; Ning, CP; Wang, HW; Wang, J; Xuan, C; Zhang, BB; Zhao, JX | 1 |
| Berardo, C; Di Pasqua, LG; Ferrigno, A; Richelmi, P; Rizzo, V; Vairetti, M | 1 |
| Chien, SJ; Hsu, CN; Lin, IC; Lo, MH; Tain, YL | 1 |
| Bawden, CS; Fraser, CK; Kuchel, TR; Middleton, B; Morton, AJ; Pennings, JL; Rudiger, SR; Skene, DJ | 1 |
| Arós, F; Clish, CB; Corella, D; Estruch, R; Fitó, M; Gómez-Gracia, E; Guasch-Ferré, M; Hruby, A; Hu, FB; Lapetra, J; Liang, L; Martínez-González, MA; Romaguera, D; Ros, E; Ruiz-Canela, M; Salas-Salvadó, J; Serra-Majem, L; Toledo, E; Wang, DD; Yu, E | 1 |
| Ali-Sisto, T; Honkalampi, K; Koivumaa-Honkanen, H; Lehto, SM; Mäntyselkä, P; Nandania, J; Ruusunen, A; Tolmunen, T; Valkonen-Korhonen, M; Velagapudi, V; Viinamäki, H | 1 |
| Fingerhut, R; Huang, J; Ming, XF; Pillai, SM; Seebeck, P; Verrey, F; Yang, Z | 1 |
| Bondesson, U; Hedeland, M; Lundgren, J; Rådegran, G; Sandqvist, A; Wikström, G | 1 |
| Arós, F; Bullo, M; Clish, C; Cofán, M; Corella, D; Dennis, C; Estruch, R; Fitó, M; Guasch-Ferré, M; Gutiérrez-Bedmar, M; Hu, FB; Lapetra, J; Liang, L; Martínez-González, MA; Papandreou, C; Razquin, C; Romaguera, D; Ros, E; Ruiz-Canela, M; Salas-Salvadó, J; Serra-Majem, L; Sorlí, JV; Toledo, E; Wang, DD; Yu, E | 1 |
| Dzięgiel, P; Fleszar, MG; Gomułkiewicz, A; Kucharska, AZ; Magdalan, J; Matuszewska, A; Nowak, B; Piórecki, N; Rapak, A; Sozański, T; Szeląg, A; Szumny, D; Trocha, M; Wiśniewski, J | 1 |
| Barrio, RJ; Benito, S; Goicolea, MA; Sánchez-Ortega, A; Unceta, N | 1 |
| Bollenbach, A; Brunner, G; Hanff, E; Tsikas, D | 1 |
| Auge, D; Chafai, A; Fromm, MF; Gessner, A; Maas, R; Mieth, M; Müller, F | 1 |
| Bednarz-Misa, I; Bronowicka-Szydełko, A; Fleszar, MG; Gacka, M; Gamian, A; Kędzior, K; Krzystek-Korpacka, M; Masłowski, L; Wiśniewski, J; Witkiewicz, W | 1 |
| Diakowska, D; Fleszar, MG; Gamian, A; Krzystek-Korpacka, M; Wiśniewski, J; Zboch, M | 1 |
| Coleman, E; Cruse, MH; Grasemann, H; Holguin, F; Perez, N; Que, LG; Scialla, TJ; Sharma, S; Smith, V; Wasil, K; Winnica, D | 1 |
| Bassu, S; Carru, C; Castagna, F; Erre, GL; Mangoni, AA; Passiu, G; Piga, M; Sotgia, S; Zinellu, A | 1 |
| Appel, D; Böger, R; Goetz, AE; Hannemann, J; Heinze, G; Windolph, J | 1 |
| Molek, P; Nessler, J; Wlodarczyk, A; Zalewski, J; Zmudzki, P | 1 |
| Appel, D; Böger, R; Czorlich, P; Haddad, M; Hannemann, J; Lamszus, K; Mader, MM; Mohme, M; Schwedhelm, E; Westphal, M | 1 |
| Doroszko, A; Fortuna, P; Gajecki, D; Gawryś, J; Szahidewicz-Krupska, E; Wiśniewski, J | 1 |
| Guo, M; Jiang, GT; Liu, H; Liu, J; She, J; Zhou, B | 1 |
| Drapała, A; Samborowska, E; Szlęzak, D; Ufnal, M; Wróbel, M | 1 |
2 review(s) available for n,n-dimethylarginine and citrulline
| Article | Year |
|---|---|
L-arginine: a new opportunity in the management of clinical derangements in dialysis patients.
Topics: Adult; Aged; Animals; Arginine; Citrulline; Diabetic Nephropathies; Endothelium, Vascular; Female; Humans; Hypertension; Kidney Failure, Chronic; Male; Middle Aged; Nitric Oxide; Renal Dialysis | 2006 |
Asymmetric dimethylarginine (ADMA) in vascular, renal and hepatic disease and the regulatory role of L-arginine on its metabolism.
Topics: Arginine; Citrulline; Dietary Supplements; Hepatocytes; Homocysteine; Humans; Kidney Diseases; Liver Diseases; Nitric Oxide Synthase; Obesity; Risk Factors; Vascular Diseases | 2007 |
6 trial(s) available for n,n-dimethylarginine and citrulline
| Article | Year |
|---|---|
Pharmacokinetic and pharmacodynamic properties of oral L-citrulline and L-arginine: impact on nitric oxide metabolism.
Topics: Administration, Oral; Arginine; Citrulline; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Male; Middle Aged; Nitric Oxide; Nitric Oxide Synthase; Placebos; Vasodilation | 2008 |
Short-term effects of L-citrulline supplementation on arterial stiffness in middle-aged men.
Topics: Ankle Brachial Index; Arginine; Blood Pressure; Citrulline; Humans; Male; Middle Aged; Nitric Oxide; Nitric Oxide Synthase Type III; Placebos; Pulsatile Flow; Vascular Stiffness | 2012 |
Oral L-arginine supplementation in patients with mild arterial hypertension and its effect on plasma level of asymmetric dimethylarginine, L-citruline, L-arginine and antioxidant status.
Topics: Administration, Oral; Adult; Antioxidants; Arginine; Blood Pressure Monitoring, Ambulatory; Citrulline; Dietary Supplements; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Hypertension; Male | 2012 |
Digital plethysmography and arginine metabolism in prehypertension: effect of nebivolol therapy.
Topics: Adult; Antihypertensive Agents; Arginine; Benzopyrans; Blood Pressure; Citrulline; Endothelium, Vascular; Ethanolamines; Female; Humans; Male; Middle Aged; Nebivolol; Nitric Oxide; Plethysmography; Prehypertension; Prospective Studies; Regional Blood Flow | 2015 |
L-Citrulline increases nitric oxide and improves control in obese asthmatics.
Topics: Adult; Aged; Arginine; Asthma; Citrulline; Dietary Supplements; Female; Forced Expiratory Volume; Humans; Male; Middle Aged; Nitric Oxide; Nitric Oxide Synthase Type II; Obesity; Oxidative Stress; Pilot Projects; Proof of Concept Study; Severity of Illness Index; Treatment Outcome; Young Adult | 2019 |
Asymmetric dimethylarginine predicts perioperative cardiovascular complications in patients undergoing medium-to-high risk non-cardiac surgery.
Topics: Arginine; C-Reactive Protein; Citrulline; Humans; Prospective Studies | 2020 |
45 other study(ies) available for n,n-dimethylarginine and citrulline
| Article | Year |
|---|---|
Developing dual and specific inhibitors of dimethylarginine dimethylaminohydrolase-1 and nitric oxide synthase: toward a targeted polypharmacology to control nitric oxide.
Topics: Amidines; Amidohydrolases; Crystallography, X-Ray; Drug Delivery Systems; Enzyme Inhibitors; Humans; Nitric Oxide; Nitric Oxide Synthase Type I; Ornithine; Recombinant Proteins; Substrate Specificity; Thiourea | 2009 |
Occurrence of a new enzyme catalyzing the direct conversion of NG,NG-dimethyl-L-arginine to L-citrulline in rats.
Topics: Amidohydrolases; Animals; Arginine; Citrulline; Female; Hydrolases; Kidney; Mass Spectrometry; Rats; Rats, Inbred Strains | 1987 |
Response of cerebral blood vessels to an endogenous inhibitor of nitric oxide synthase.
Topics: Animals; Arginine; Basilar Artery; Brain; Cerebellum; Cerebrovascular Circulation; Citrulline; Nitric Oxide Synthase; Rabbits; Rats; Rats, Sprague-Dawley | 1995 |
Metabolism of methylarginines by human vasculature; implications for the regulation of nitric oxide synthesis.
Topics: Amino Acid Oxidoreductases; Arginase; Arginine; Cells, Cultured; Chromatography, High Pressure Liquid; Citrulline; Cytosol; Endothelium, Vascular; Humans; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Saphenous Vein; Umbilical Veins | 1994 |
Determination of arginine and asymmetric dimethylarginine (ADMA) in human plasma by liquid chromatography/mass spectrometry with the isotope dilution technique.
Topics: Adult; Aged; Arginine; Calibration; Carbon Isotopes; Chromatography, Liquid; Citrulline; Female; Humans; Indicator Dilution Techniques; Kidney Failure, Chronic; Male; Mass Spectrometry; Middle Aged; Plasma; Sensitivity and Specificity | 2004 |
Adverse effects of cigarette smoke on NO bioavailability: role of arginine metabolism and oxidative stress.
Topics: Adult; Animals; Antioxidants; Arginine; Biological Availability; Biological Transport; Cationic Amino Acid Transporter 1; Cattle; Cells, Cultured; Citrulline; Cotinine; Culture Media; Endothelial Cells; Enzyme Activation; Humans; Male; Nicotiana; Nitric Oxide; Nitric Oxide Synthase; Oxidants; Oxidative Stress; Reactive Oxygen Species; Smoke; Smoking | 2006 |
Determination of dimethylarginine dimethylaminohydrolase activity in the kidney.
Topics: Amidohydrolases; Animals; Arginine; Citrulline; Kidney; Male; Rats; Rats, Sprague-Dawley; Urea | 2007 |
Association of an endogenous inhibitor of nitric oxide synthase with cerebral vasospasm in patients with aneurysmal subarachnoid hemorrhage.
Topics: Adult; Aged; Arginine; Arnold-Chiari Malformation; Citrulline; Enzyme Inhibitors; Female; Humans; Intracranial Aneurysm; Male; Middle Aged; Nitric Oxide Synthase; Nitrites; Subarachnoid Hemorrhage; Vasospasm, Intracranial | 2007 |
Endogenous nitric oxide synthase inhibitors in sickle cell disease: abnormal levels and correlations with pulmonary hypertension, desaturation, haemolysis, organ dysfunction and death.
Topics: Anemia, Sickle Cell; Arginine; Case-Control Studies; Citrulline; Follow-Up Studies; Hemolysis; Humans; Hypertension, Pulmonary; Kidney Diseases; Linear Models; Nitric Oxide Synthase; omega-N-Methylarginine; Oxygen; Proportional Hazards Models; Risk; Survival Rate | 2009 |
Targeted metabolomic evaluation of arginine methylation and cardiovascular risks: potential mechanisms beyond nitric oxide synthase inhibition.
Topics: Aged; Arginine; Biomarkers; C-Reactive Protein; Cardiovascular Diseases; Chromatography, High Pressure Liquid; Citrulline; Coronary Artery Disease; Creatinine; Female; Humans; Lysine; Male; Metabolomics; Methylation; Middle Aged; Nitric Oxide Synthase; Odds Ratio; omega-N-Methylarginine; Ornithine; Prognosis; Prospective Studies; Protein Processing, Post-Translational; Risk Assessment; Risk Factors; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Time Factors | 2009 |
Human alanine-glyoxylate aminotransferase 2 lowers asymmetric dimethylarginine and protects from inhibition of nitric oxide production.
Topics: Adenoviridae; Animals; Arginine; Atherosclerosis; Chlorocebus aethiops; Citrulline; COS Cells; Diabetes Mellitus; Endothelial Cells; Gene Expression; Heart Failure; Humans; Hydrolysis; Hypertension; Kidney; Liver; Mice; Mitochondria; Nitric Oxide; Nitric Oxide Synthase; Transaminases; Transduction, Genetic | 2010 |
Effects of angiotensin type 1 receptor blockade on arginine and ADMA synthesis and metabolic pathways in fawn-hooded hypertensive rats.
Topics: Amidohydrolases; Angiotensin II Type 1 Receptor Blockers; Animals; Arginine; Biphenyl Compounds; Citrulline; Hypertension; Irbesartan; Male; Metabolic Networks and Pathways; Nitric Oxide; Rats; Tetrazoles | 2010 |
Simultaneous quantitative determination of N(G),N(G)-dimethyl-L-arginine or asymmetric dimethylarginine and related pathway's metabolites in biological fluids by ultrahigh-performance liquid chromatography/electrospray ionization-tandem mass spectrometry.
Topics: Adult; Arginine; Body Fluids; Chromatography, High Pressure Liquid; Citrulline; Enzyme Inhibitors; Humans; Infant, Newborn; Middle Aged; Nitric Oxide; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry | 2010 |
Melatonin prevents hypertension and increased asymmetric dimethylarginine in young spontaneous hypertensive rats.
Topics: Analysis of Variance; Animals; Arginine; Blood Pressure; Blotting, Western; Body Weight; Citrulline; Histocytochemistry; Hypertension; Male; Melatonin; Nitric Oxide; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type III; Organ Size; Oxidative Stress; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 2010 |
Nitric oxide synthase inhibitors and cerebral vasospasm.
Topics: Animals; Arginine; Citrulline; Enzyme Inhibitors; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; S-Adenosylmethionine; Vasospasm, Intracranial | 2011 |
The role of asymmetric dimethyl arginine and oxidant/antioxidant system in preeclampsia.
Topics: Adult; Antioxidants; Arginine; Case-Control Studies; Citrulline; Female; Fetal Blood; Humans; Lipid Peroxidation; Malondialdehyde; Oxidants; Oxidative Stress; Pre-Eclampsia; Pregnancy; Young Adult | 2011 |
Continuous exposure to L-arginine induces oxidative stress and physiological tolerance in cultured human endothelial cells.
Topics: Arginase; Arginine; Ascorbic Acid; Cells, Cultured; Citrulline; Culture Media; Down-Regulation; Drug Tolerance; Free Radical Scavengers; Gene Expression; Glucose; Human Umbilical Vein Endothelial Cells; Humans; Nitrates; Nitric Oxide Synthase Type III; Nitrites; Oxidative Stress; Polyethylene Glycols; Superoxide Dismutase; Superoxides | 2012 |
Endotoxemia exacerbates kidney injury and increases asymmetric dimethylarginine in young bile duct-ligated rats.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Acute Kidney Injury; Animals; Arginine; Bile Ducts; Blotting, Western; Chromatography, High Pressure Liquid; Citrulline; Deoxyguanosine; Endotoxemia; Immunohistochemistry; Male; Rats; Rats, Sprague-Dawley | 2012 |
Nitric oxide and L-arginine metabolism in a devascularized porcine model of acute liver failure.
Topics: Animals; Arginase; Arginine; Citrulline; Disease Models, Animal; Female; Liver; Liver Failure, Acute; Nitric Oxide; Ornithine; Portacaval Shunt, Surgical; Sus scrofa | 2012 |
Aminoguanidine attenuates hypertension, whereas 7-nitroindazole exacerbates kidney damage in spontaneously hypertensive rats: the role of nitric oxide.
Topics: Amidohydrolases; Animals; Arginine; Blood Pressure; Citrulline; Guanidines; Hypertension; Indazoles; Kidney Diseases; Male; Nitric Oxide; Nitric Oxide Synthase Type I; Rats; Rats, Inbred SHR; Sodium Chloride, Dietary; Up-Regulation | 2013 |
Two different approaches to restore renal nitric oxide and prevent hypertension in young spontaneously hypertensive rats: l-citrulline and nitrate.
Topics: Animals; Arginine; Citrulline; Dietary Supplements; Hypertension; Male; Nitrates; Nitric Oxide; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 2014 |
Ligand-dependent dynamics of the active-site lid in bacterial dimethylarginine dimethylaminohydrolase.
Topics: Amidohydrolases; Arginine; Catalytic Domain; Citrulline; Kinetics; Ligands; Molecular Dynamics Simulation; Nuclear Magnetic Resonance, Biomolecular; Pseudomonas aeruginosa | 2014 |
Is arginine/asymetric dimethylarginine ratio depletion an indicator of insufficient resuscitation in a porcine model of hemorrhage-reperfusion?
Topics: Animals; Arginine; Biomarkers; Chromatography, Liquid; Citrulline; Female; Fluid Therapy; Interleukin-6; Male; Mass Spectrometry; Resuscitation; Shock, Hemorrhagic; Sus scrofa | 2014 |
Renal transplantation promptly restores excretory function but disturbed L-arginine metabolism persists in patients during the early period after surgery.
Topics: Adult; Arginine; Citrulline; Creatinine; Female; Humans; Kidney Transplantation; Male; Middle Aged; Nitric Oxide; Postoperative Complications; Young Adult | 2015 |
L-citrulline for protection of endothelial function from ADMA-induced injury in porcine coronary artery.
Topics: Animals; Arginine; Cardiovascular Agents; Citrulline; Coronary Vessels; Cyclic GMP; Drug Evaluation, Preclinical; Endothelium, Vascular; Nitric Oxide Synthase Type III; Phosphorylation; Protein Processing, Post-Translational; Superoxides; Sus scrofa; Vascular System Injuries | 2015 |
Changes in Biliary Levels of Arginine and its Methylated Derivatives after Hepatic Ischaemia/Reperfusion.
Topics: Alanine Transaminase; Alkaline Phosphatase; Amidohydrolases; Amino Acid Transport Systems, Basic; Animals; Arginine; Aspartate Aminotransferases; Bile; Citrulline; Liver; Liver Diseases; Male; Nitric Oxide; Rats; Rats, Wistar; Reperfusion Injury; RNA, Messenger | 2016 |
Low urinary citrulline/arginine ratio associated with blood pressure abnormalities and arterial stiffness in childhood chronic kidney disease.
Topics: Adolescent; Arginine; Biomarkers; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Child; Citrulline; Female; Humans; Hypertension; Male; Nitric Oxide; Nitric Oxide Synthase; Pulse Wave Analysis; Renal Insufficiency, Chronic; Taiwan; Vascular Remodeling; Vascular Stiffness | 2016 |
Metabolic profiling of presymptomatic Huntington's disease sheep reveals novel biomarkers.
Topics: Amino Acids, Branched-Chain; Animals; Animals, Genetically Modified; Area Under Curve; Arginine; Biomarkers; Citrulline; Genotype; Huntington Disease; Logistic Models; Metabolomics; ROC Curve; Sheep | 2017 |
Plasma Arginine/Asymmetric Dimethylarginine Ratio and Incidence of Cardiovascular Events: A Case-Cohort Study.
Topics: Aged; Arginine; Cardiovascular Diseases; Case-Control Studies; Chromatography, Liquid; Citrulline; Cohort Studies; Female; Humans; Incidence; Male; Middle Aged; Multivariate Analysis; Myocardial Infarction; omega-N-Methylarginine; Ornithine; Proportional Hazards Models; Prospective Studies; Risk Factors; Stroke; Tandem Mass Spectrometry | 2017 |
Global arginine bioavailability ratio is decreased in patients with major depressive disorder.
Topics: Adult; Aged; Arginine; Biological Availability; Citrulline; Depressive Disorder, Major; Female; Humans; Male; Middle Aged; Nitric Oxide; Ornithine; Oxidative Stress; Surveys and Questionnaires; Young Adult | 2018 |
Kidney Mass Reduction Leads to l-Arginine Metabolism-Dependent Blood Pressure Increase in Mice.
Topics: Animals; Arginase; Arginine; Blood Pressure; Citrulline; Female; Kidney; Male; Mice, Inbred C57BL; Mice, Knockout; Nephrectomy; Nitric Oxide; Organ Size | 2018 |
Alterations in plasma L-arginine and methylarginines in heart failure and after heart transplantation.
Topics: Arginine; Biomarkers; Citrulline; Endothelium, Vascular; Female; Heart Failure; Heart Transplantation; Hemodynamics; Humans; Male; Middle Aged; Nitric Oxide; Ornithine; Prospective Studies; Time Factors; Treatment Outcome | 2018 |
Changes in arginine are inversely associated with type 2 diabetes: A case-cohort study in the PREDIMED trial.
Topics: Aged; Aged, 80 and over; Arginine; Case-Control Studies; Citrulline; Cohort Studies; Diabetes Mellitus, Type 2; Diet, Fat-Restricted; Diet, Mediterranean; Female; Humans; Incidence; Insulin Resistance; Male; Middle Aged; omega-N-Methylarginine; Ornithine; Risk Factors | 2019 |
The iridoid loganic acid and anthocyanins from the cornelian cherry (Cornus mas L.) fruit increase the plasma l-arginine/ADMA ratio and decrease levels of ADMA in rabbits fed a high-cholesterol diet.
Topics: Amidohydrolases; Animals; Anthocyanins; Arginine; Atherosclerosis; Cholesterol, Dietary; Citrulline; Cornus; Dimethylamines; Fruit; Iridoids; Liver; Male; Nitric Oxide Synthase Type III; Rabbits | 2019 |
LC-QQQ-MS routine analysis method for new biomarker quantification in plasma aimed at early chronic kidney disease diagnosis.
Topics: Arginine; Biomarkers; Child; Child, Preschool; Chromatography, Liquid; Citrulline; Creatinine; Early Diagnosis; Female; Glomerular Filtration Rate; Humans; Male; Metabolomics; Plasma; Renal Insufficiency, Chronic; S-Adenosylmethionine; Tandem Mass Spectrometry | 2019 |
Asymmetric dimethylation and citrullination of proteinic arginine and homoarginine synthesis in human Helicobacter pylori infection.
Topics: Adult; Aged; Aged, 80 and over; Arginine; Citrullination; Citrulline; Female; Gas Chromatography-Mass Spectrometry; Helicobacter Infections; Helicobacter pylori; Homoarginine; Humans; Lysine; Male; Methylation; Middle Aged; Nitric Oxide; Ornithine | 2019 |
Establishment of reference values for the lysine acetylation marker N
Topics: Adolescent; Adult; Arginine; Biomarkers; Cardiovascular Diseases; Carnitine; Chromatography, Liquid; Citrulline; Creatinine; Female; Homoarginine; Humans; Lysine; Male; Middle Aged; Ornithine; Reference Values; Renal Insufficiency, Chronic; Tandem Mass Spectrometry; Young Adult | 2019 |
Metabolites of the Nitric Oxide (NO) Pathway Are Altered and Indicative of Reduced NO and Arginine Bioavailability in Patients with Cardiometabolic Diseases Complicated with Chronic Wounds of Lower Extremities: Targeted Metabolomics Approach (LC-MS/MS).
Topics: Aged; Arginine; Cardiovascular Diseases; Case-Control Studies; Chemokines; Citrulline; Cytokines; Female; Growth Hormone; Humans; Lower Extremity; Male; Metabolomics; Middle Aged; Nitric Oxide; Wounds and Injuries | 2019 |
Targeted metabolomic analysis of nitric oxide/L-arginine pathway metabolites in dementia: association with pathology, severity, and structural brain changes.
Topics: Arginine; Biomarkers; Brain; Citrulline; Dementia; Female; Humans; Male; Metabolomics; Middle Aged; Nitric Oxide; Signal Transduction | 2019 |
Comprehensive arginine metabolomics and peripheral vasodilatory capacity in rheumatoid arthritis: A monocentric cross-sectional study.
Topics: Aged; Aged, 80 and over; Arginine; Arthritis, Rheumatoid; Biomarkers; Case-Control Studies; Citrulline; Cross-Sectional Studies; Female; Fingers; Homoarginine; Humans; Italy; Male; Metabolomics; Middle Aged; Vasodilation | 2020 |
The shifted balance of arginine metabolites in acute myocardial infarction patients and its clinical relevance.
Topics: Arginine; Citrulline; Coronary Angiography; Female; Humans; Male; Middle Aged; Ornithine; Proline; ST Elevation Myocardial Infarction; Treatment Outcome | 2021 |
Intrathecal and systemic alterations of L-arginine metabolism in patients after intracerebral hemorrhage.
Topics: Aged; Arginine; Case-Control Studies; Cerebral Hemorrhage; Chromatography, High Pressure Liquid; Citrulline; Female; Humans; Male; Middle Aged; Nitric Oxide; Nitric Oxide Synthase; Ornithine; Risk Factors; Tandem Mass Spectrometry; Up-Regulation | 2021 |
A Cross-Talk between the Erythrocyte L-Arginine/ADMA/Nitric Oxide Metabolic Pathway and the Endothelial Function in Subjects with Type 2 Diabetes Mellitus.
Topics: Adult; Aged; Aged, 80 and over; Arginine; Citrulline; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Endothelium, Vascular; Erythrocytes; Female; Humans; Male; Metabolic Networks and Pathways; Middle Aged; Nitric Oxide | 2021 |
Dysregulated Arginine Metabolism in Young Patients with Chronic Persistent Asthma and in Human Bronchial Epithelial Cells.
Topics: Adult; Arginine; Asthma; Bronchi; Case-Control Studies; Cell Culture Techniques; Chronic Disease; Citrulline; Eosinophils; Epithelial Cells; Female; Humans; Male; Nitric Oxide; Ornithine; Prospective Studies; Young Adult | 2021 |
Urinary excretion of asymmetric (ADMA) and symmetric (SDMA) dimethylarginine is positively related to nitric oxide level in tissues of normotensive and hypertensive rats.
Topics: Animals; Arginine; Chromatography, Liquid; Citrulline; Hypertension; Male; Nitric Oxide; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Tandem Mass Spectrometry | 2023 |