Compounds > n,n-dimethylarginine
Page last updated: 2024-09-03

n,n-dimethylarginine and angiotensin ii

n,n-dimethylarginine has been researched along with angiotensin ii in 19 studies

Compound Research Comparison

Studies
(n,n-dimethylarginine)		Trials
(n,n-dimethylarginine)		Recent Studies (post-2010)
(n,n-dimethylarginine)		Studies
(angiotensin ii)		Trials
(angiotensin ii)		Recent Studies (post-2010) (angiotensin ii)
2,2162281,22138,1521,0897,413

Protein Interaction Comparison

ProteinTaxonomyn,n-dimethylarginine (IC50)angiotensin ii (IC50)
Atrial natriuretic peptide receptor 3Homo sapiens (human)0.002
Type-1A angiotensin II receptor Rattus norvegicus (Norway rat)0.002
Type-1B angiotensin II receptorRattus norvegicus (Norway rat)0.0018
Type-1 angiotensin II receptorHomo sapiens (human)0.0055
Type-2 angiotensin II receptorRattus norvegicus (Norway rat)0.004
Type-2 angiotensin II receptorHomo sapiens (human)0.0011

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's8 (42.11)29.6817
2010's11 (57.89)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hirata, Y1
Bauersachs, J; Thum, T1
Zoccali, C1
Berti, F; Berti, M; Bianchi, M; Bonomo, S; De Gennaro Colonna, V; Ferrario, P; Guazzi, M; Manfredi, B; Muller, EE; Rossoni, G1
Chen, MF; Li, YJ; Luo, BL; Wang, YJ; Xie, XM; Yang, TL; Zhang, XH1
Hasegawa, K; Hayashi, K; Homma, K; Itoh, H; Kimoto, M; Sugano, N; Tatematsu, S; Wakino, S; Yoshioka, K1
Bode-Böger, SM; Bukowska, A; Lendeckel, U; Martens-Lobenhoffer, J; Scalera, F; Täger, M1
Koller, A; Lotz, G; Racz, A; Veresh, Z1
Baylis, C; Croker, B; Cunningham, MW; Moningka, NC; Sasser, JM1
Aslam, S; Griendling, K; Luo, Z; Teerlink, T; Welch, WJ; Wilcox, CS1
Aslam, S; Falck, JR; Jose, PA; Luo, Z; Teerlink, T; Wang, D; Wang, X; Welch, WJ; Wilcox, CS1
Helle, F; Hultström, M; Iversen, BM; Palm, F; Schwartz, D; Schwartz, IF; Skogstrand, T1
Baylis, C; Cunningham, MW; Sasser, JM1
Chen, L; Cheng, G; Huang, X; Peng, H; Shi, R; Yang, T; Yu, Z; Zhang, G1
Jiao, PL; Li, JK; Liu, B; Sun, JC; Tan, X; Wang, WZ; Wang, YK; Wu, ZT1
Buszman, E; Jasik, K; Rzepecka-Stojko, A; Stojko, J1
Niu, M; Shi, R; Wang, Y; Yin, S; Zhang, F1
Cai, GW; Cheng, P; Ding, L; Gao, S; Hu, J; Huang, GY; Wang, L; Zhang, YX1
Ge, LJ; Peng, XD; Sun, JC; Tan, X; Wang, WZ; Yang, RH1

Reviews

3 review(s) available for n,n-dimethylarginine and angiotensin ii

ArticleYear
[NO and hypertension].
    Nihon rinsho. Japanese journal of clinical medicine, 2004, Volume: 62 Suppl 3

    Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Arginine; Arteriosclerosis; Biopterins; C-Reactive Protein; Endothelium, Vascular; Humans; Hypertension; Mutation; NADPH Oxidases; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Perindopril; Reactive Oxygen Species; Vasodilation

2004
Spotlight on endothelial progenitor cell inhibitors: short review.
    Vascular medicine (London, England), 2005, Volume: 10 Suppl 1

    Topics: Angiotensin II; Animals; Arginine; Atherosclerosis; Bone Marrow Cells; Cell Differentiation; Cell Movement; Endothelial Cells; Humans; Lipoproteins, LDL; Nitric Oxide; Stem Cells

2005
Asymmetric dimethylarginine in end-stage renal disease patients: a biomarker modifiable by calcium blockade and angiotensin II antagonism?
    Kidney international, 2006, Volume: 70, Issue:12

    Topics: Amlodipine; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Arginine; Biomarkers; Calcium; Calcium Channel Blockers; Humans; Kidney Failure, Chronic; Risk Factors; Tetrazoles; Valine; Valsartan

2006

Other Studies

16 other study(ies) available for n,n-dimethylarginine and angiotensin ii

ArticleYear
Asymmetric dimethylarginine (ADMA) induces vascular endothelium impairment and aggravates post-ischemic ventricular dysfunction in rats.
    European journal of pharmacology, 2007, Feb-28, Volume: 557, Issue:2-3

    Topics: Acetylcholine; Angiotensin II; Animals; Aorta; Arginine; Blood Pressure; Endothelium, Vascular; Enzyme Inhibitors; Heart Rate; Male; Myocardial Reperfusion Injury; Nitrates; Nitrites; Perfusion; Rats; Rats, Wistar; RNA, Messenger; Vasoconstrictor Agents; Vasodilator Agents; Ventricular Dysfunction

2007
Role of asymmetric dimethylarginine in inflammatory reactions by angiotensin II.
    Journal of vascular research, 2007, Volume: 44, Issue:5

    Topics: Amidohydrolases; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Arginine; Cell Adhesion; Cells, Cultured; Culture Media, Conditioned; Endothelial Cells; Endothelium, Vascular; Gene Expression Regulation; Humans; Interleukin-8; Losartan; Monocytes; NF-kappa B; Nitrates; Nitric Oxide; Nitrites; Protein-Arginine N-Methyltransferases; Reactive Oxygen Species; Receptors, Interleukin-8B; Repressor Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Necrosis Factor-alpha; Umbilical Veins; Vasculitis; Vasodilation

2007
Role of asymmetric dimethylarginine in vascular injury in transgenic mice overexpressing dimethylarginie dimethylaminohydrolase 2.
    Circulation research, 2007, Jul-20, Volume: 101, Issue:2

    Topics: Amidohydrolases; Amlodipine; Angiotensin II; Animals; Arginine; Blood Pressure; Coronary Circulation; Coronary Vessels; Creatine Kinase, MB Form; Enzyme Activation; Enzyme Inhibitors; Fibrosis; Heart Diseases; Imidazoles; Mice; Mice, Transgenic; Myocardium; Nitric Oxide; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Peptidyl-Dipeptidase A; Pyridines; Time Factors; Tunica Media; Up-Regulation; Vasodilator Agents

2007
Effect of telmisartan on nitric oxide--asymmetrical dimethylarginine system: role of angiotensin II type 1 receptor gamma and peroxisome proliferator activated receptor gamma signaling during endothelial aging.
    Hypertension (Dallas, Tex. : 1979), 2008, Volume: 51, Issue:3

    Topics: Acrylates; Amidohydrolases; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Anilides; Arginine; Benzimidazoles; Benzoates; Cells, Cultured; Cellular Senescence; Down-Regulation; Endothelium, Vascular; Humans; Imidazoles; Nitric Oxide; Oxidative Stress; PPAR gamma; Receptor, Angiotensin, Type 1; Signal Transduction; Telmisartan; Thiophenes; Up-Regulation

2008
ADMA impairs nitric oxide-mediated arteriolar function due to increased superoxide production by angiotensin II-NAD(P)H oxidase pathway.
    Hypertension (Dallas, Tex. : 1979), 2008, Volume: 52, Issue:5

    Topics: Acetophenones; Angiotensin II; Animals; Arginine; Arterioles; Enzyme Inhibitors; Losartan; Male; Muscle, Skeletal; NADPH Oxidases; Nitric Oxide; Oxidative Stress; Quinapril; Rats; Rats, Wistar; Signal Transduction; Superoxides; Tetrahydroisoquinolines; Vasoconstriction; Vasodilation

2008
Asymmetric dimethylarginine in angiotensin II-induced hypertension.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2010, Volume: 298, Issue:3

    Topics: Amidohydrolases; Angiotensin II; Animals; Arginine; Blood Pressure; Fibrosis; Hypertension, Renal; Kidney Cortex; Male; NADPH Oxidases; Nitrates; Nitrites; Oxidative Stress; Protein-Arginine N-Methyltransferases; Rats; Rats, Sprague-Dawley; Thiobarbituric Acid Reactive Substances; Vasoconstrictor Agents

2010
Angiotensin II and NADPH oxidase increase ADMA in vascular smooth muscle cells.
    Hypertension (Dallas, Tex. : 1979), 2010, Volume: 56, Issue:3

    Topics: Analysis of Variance; Angiotensin II; Animals; Arginine; Benzimidazoles; Biphenyl Compounds; Blotting, Western; Cells, Cultured; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; NADPH Oxidases; Rats; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction; Tetrazoles

2010
Impaired endothelial function and microvascular asymmetrical dimethylarginine in angiotensin II-infused rats: effects of tempol.
    Hypertension (Dallas, Tex. : 1979), 2010, Volume: 56, Issue:5

    Topics: Analysis of Variance; Angiotensin II; Animals; Antioxidants; Arginine; Arterioles; Cyclic N-Oxides; Endothelium, Vascular; Male; Malondialdehyde; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Spin Labels; Vasoconstrictor Agents

2010
Nitric oxide in afferent arterioles after uninephrectomy depends on extracellular L-arginine.
    American journal of physiology. Renal physiology, 2013, Apr-15, Volume: 304, Issue:8

    Topics: Angiotensin II; Animals; Arginine; Arterioles; Blood Pressure; Body Weight; Enzyme Inhibitors; Extracellular Space; Glomerular Filtration Rate; Homeostasis; Male; Nephrectomy; NG-Nitroarginine Methyl Ester; Nitric Oxide; Organ Size; Rats; Rats, Wistar; Renal Circulation; Vasoconstrictor Agents

2013
Serelaxin reduces oxidative stress and asymmetric dimethylarginine in angiotensin II-induced hypertension.
    American journal of physiology. Renal physiology, 2014, Dec-15, Volume: 307, Issue:12

    Topics: Angiotensin II; Animals; Antihypertensive Agents; Antioxidants; Arginine; Arterial Pressure; Dinoprost; Disease Models, Animal; Down-Regulation; Humans; Hypertension; Injections, Subcutaneous; Kidney; Liver; Male; NADPH Oxidases; Nitric Oxide; Oxidative Stress; Proteinuria; Rats, Sprague-Dawley; Recombinant Proteins; Relaxin; Thiobarbituric Acid Reactive Substances

2014
Vascular peroxidase 1 up regulation by angiotensin II attenuates nitric oxide production through increasing asymmetrical dimethylarginine in HUVECs.
    Journal of the American Society of Hypertension : JASH, 2016, Volume: 10, Issue:9

    Topics: Amidohydrolases; Angiotensin II; Animals; Aorta; Arginine; Cells, Cultured; Endothelium, Vascular; Gene Knockdown Techniques; Hemeproteins; Human Umbilical Vein Endothelial Cells; Humans; Hydrogen Peroxide; Hypertension; Hypochlorous Acid; Male; NADPH Oxidases; Nitric Oxide; Nitric Oxide Synthase Type III; Peroxidases; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Recombinant Proteins; RNA, Small Interfering; Up-Regulation

2016
The asymmetric dimethylarginine-mediated inhibition of nitric oxide in the rostral ventrolateral medulla contributes to regulation of blood pressure in hypertensive rats.
    Nitric oxide : biology and chemistry, 2017, Jul-01, Volume: 67

    Topics: Amidohydrolases; Angiotensin II; Animals; Arginine; Blood Pressure; Heart Rate; Kidney; Losartan; Male; Medulla Oblongata; Nitric Oxide; omega-N-Methylarginine; Protein-Arginine N-Methyltransferases; Rats, Inbred WKY; Rats, Sprague-Dawley; Sympathetic Nervous System

2017
Anti-Atherogenic Activity of Polyphenol-Rich Extract from Bee Pollen.
    Nutrients, 2017, Dec-18, Volume: 9, Issue:12

    Topics: Angiotensin II; Animals; Arginine; Atherosclerosis; Bees; Cholesterol; Coronary Artery Disease; Diet, High-Fat; Dose-Response Relationship, Drug; Female; Hypercholesterolemia; Mice; Mice, Inbred C57BL; Mice, Knockout; Oxidative Stress; Peptidyl-Dipeptidase A; Pollen; Polyphenols

2017
Nephroprotective effects of nebivolol in 2K1C rats through regulation of the kidney ROS-ADMA-NO pathway.
    Pharmacological reports : PR, 2018, Volume: 70, Issue:5

    Topics: Amidohydrolases; Angiotensin II; Animals; Arginine; Atenolol; Blood Pressure; Hypertension, Renovascular; Kidney; Kidney Function Tests; Male; NADPH Oxidases; Nebivolol; Nitric Oxide; Nitric Oxide Synthase; Protective Agents; Protein-Arginine N-Methyltransferases; Rats; Reactive Oxygen Species; Signal Transduction

2018
The protective effects of polysaccharide extract from Xin-Ji-Er-Kang formula on Ang II-induced HUVECs injury, L-NAME-induced hypertension and cardiovascular remodeling in mice.
    BMC complementary and alternative medicine, 2019, Jun-13, Volume: 19, Issue:1

    Topics: Angiotensin II; Animals; Aorta; Arginine; Blood Pressure; Cytokines; Drug Evaluation, Preclinical; Drugs, Chinese Herbal; Endothelial Cells; Endothelium, Vascular; Human Umbilical Vein Endothelial Cells; Humans; Hypertension; Inflammation; Male; Malondialdehyde; Mice; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type III; Oxidative Stress; Phytotherapy; Superoxide Dismutase; Vascular Remodeling

2019
Interleukin enhancement binding factor 3 inhibits cardiac hypertrophy by targeting asymmetric dimethylarginine-nitric oxide.
    Nitric oxide : biology and chemistry, 2019, 12-01, Volume: 93

    Topics: Amidohydrolases; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Arginine; Cardiomegaly; Down-Regulation; Gene Knockdown Techniques; Losartan; Male; Myocytes, Cardiac; Nitric Oxide; Nuclear Factor 90 Proteins; Rats, Sprague-Dawley

2019