Page last updated: 2024-09-03

n,n-dimethylarginine and allopurinol

n,n-dimethylarginine has been researched along with allopurinol in 5 studies

Compound Research Comparison

Studies
(n,n-dimethylarginine)
Trials
(n,n-dimethylarginine)
Recent Studies (post-2010)
(n,n-dimethylarginine)
Studies
(allopurinol)
Trials
(allopurinol)
Recent Studies (post-2010) (allopurinol)
2,2162281,22115,0967433,363

Protein Interaction Comparison

ProteinTaxonomyn,n-dimethylarginine (IC50)allopurinol (IC50)
Xanthine dehydrogenase/oxidase [Includes: Xanthine dehydrogenase Rattus norvegicus (Norway rat)3.3765
Xanthine dehydrogenase/oxidaseHomo sapiens (human)3.1861
Xanthine dehydrogenase/oxidaseBos taurus (cattle)5.0758
Histamine H3 receptorCavia porcellus (domestic guinea pig)8.69

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's4 (80.00)24.3611
2020's1 (20.00)2.80

Authors

AuthorsStudies
Förstermann, U1
Gori, T; Münzel, T; Schulz, E1
Debreczeni, B; Hamar, J; Kaminski, PM; Koller, A; Veresh, Z; Wolin, MS1
Alshahawey, M; Elsaid, TW; Sabri, NA; Shahin, SM1
Doi, Y; Fukae, S; Ikeda, S; Kawano, H; Koga, S; Maemura, K; Minami, T; Nakata, T; Tsuneto, A; Yonekura, T1

Reviews

2 review(s) available for n,n-dimethylarginine and allopurinol

ArticleYear
Nitric oxide and oxidative stress in vascular disease.
    Pflugers Archiv : European journal of physiology, 2010, Volume: 459, Issue:6

    Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Antioxidants; Arginine; Aryldialkylphosphatase; Biopterins; Calcium; Cardiovascular Diseases; Catalase; Electron Transport; Glutathione Peroxidase; Heme Oxygenase (Decyclizing); Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Mitochondria; NADPH Oxidases; Nitric Oxide; Nitric Oxide Synthase Type III; Oxidative Stress; Phosphorylation; Protein Multimerization; Reactive Oxygen Species; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Risk Factors; Superoxide Dismutase; Superoxides; Thioredoxins; Vascular Diseases; Xanthine Oxidase

2010
Oxidative stress and endothelial dysfunction in hypertension.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2011, Volume: 34, Issue:6

    Topics: Animals; Arginine; Endothelium, Vascular; Humans; Hypertension; NADPH Oxidases; Nitric Oxide Synthase Type III; Oxidative Stress; Prognosis; Reactive Oxygen Species; Xanthine Oxidase

2011

Trials

2 trial(s) available for n,n-dimethylarginine and allopurinol

ArticleYear
Effect of Febuxostat on the Endothelial Dysfunction in Hemodialysis Patients: A Randomized, Placebo-Controlled, Double-Blinded Study.
    American journal of nephrology, 2017, Volume: 45, Issue:5

    Topics: Administration, Oral; Adult; Alanine Transaminase; Arginine; Aspartate Aminotransferases; C-Reactive Protein; Cardiovascular Diseases; Double-Blind Method; Endothelium, Vascular; Enzyme Inhibitors; Febuxostat; Female; Humans; Incidence; Kidney Failure, Chronic; Male; Middle Aged; Pancytopenia; Placebos; Prospective Studies; Renal Dialysis; Risk Factors; Treatment Outcome; Uric Acid; Xanthine Oxidase

2017
Randomized, Open-Label, Cross-Over Comparison of the Effects of Benzbromarone and Febuxostat on Endothelial Function in Patients with Hyperuricemia.
    International heart journal, 2020, Sep-29, Volume: 61, Issue:5

    Topics: Adiponectin; Aged; Arginine; Benzbromarone; Cross-Over Studies; Endothelium, Vascular; Febuxostat; Female; Gout Suppressants; Humans; Hyperemia; Hyperuricemia; Male; Middle Aged; Organic Anion Transporters; Organic Cation Transport Proteins; Treatment Outcome; Uric Acid; Uricosuric Agents; Xanthine Oxidase

2020

Other Studies

1 other study(ies) available for n,n-dimethylarginine and allopurinol

ArticleYear
Asymmetric dimethylarginine reduces nitric oxide donor-mediated dilation of arterioles by activating the vascular renin-angiotensin system and reactive oxygen species.
    Journal of vascular research, 2012, Volume: 49, Issue:4

    Topics: Acetophenones; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Arginine; Arterioles; Catalase; Male; Muscle, Skeletal; NADPH Oxidases; Nitric Oxide Donors; Nitric Oxide Synthase; Nitroprusside; Oxidative Stress; Pyrogallol; Rats; Rats, Wistar; Reactive Oxygen Species; Renin-Angiotensin System; Superoxide Dismutase; Vasodilation; Xanthine Oxidase

2012