n-n-dimethylalanine and methylamine

n-n-dimethylalanine has been researched along with methylamine* in 1 studies

Other Studies

1 other study(ies) available for n-n-dimethylalanine and methylamine

Article	Year
Beta-deuterium isotope effects on amine basicity, "inductive" and stereochemical. Journal of the American Chemical Society, 2003, Dec-10, Volume: 125, Issue:49 Secondary beta deuterium isotope effects on acidity constants of ammonium ions are measured using a remarkably precise NMR titration method. Deuteration is found to increase the basicity of methylamine, dimethylamine, benzylamine, and N,N-dimethylaniline. The effect is attributed to a lowered zero-point energy of a CH bond adjacent to an amine nitrogen. The method permits a determination of the stereochemical dependence of the isotope effect in a locked piperidine, and it is found that deuteration is more effective when antiperiplanar to a lone pair. The values are consistent with a cos(2) dependence on dihedral angle, with no detectable angle-independent inductive effect. Topics: Alanine; Amines; Benzylamines; Deuterium Exchange Measurement; Dimethylamines; Hydrogen-Ion Concentration; Kinetics; Magnetic Resonance Spectroscopy; Methylamines; Stereoisomerism	2003

Article

Year

Beta-deuterium isotope effects on amine basicity, "inductive" and stereochemical.

Journal of the American Chemical Society, 2003, Dec-10, Volume: 125, Issue:49

Secondary beta deuterium isotope effects on acidity constants of ammonium ions are measured using a remarkably precise NMR titration method. Deuteration is found to increase the basicity of methylamine, dimethylamine, benzylamine, and N,N-dimethylaniline. The effect is attributed to a lowered zero-point energy of a CH bond adjacent to an amine nitrogen. The method permits a determination of the stereochemical dependence of the isotope effect in a locked piperidine, and it is found that deuteration is more effective when antiperiplanar to a lone pair. The values are consistent with a cos(2) dependence on dihedral angle, with no detectable angle-independent inductive effect.

Topics: Alanine; Amines; Benzylamines; Deuterium Exchange Measurement; Dimethylamines; Hydrogen-Ion Concentration; Kinetics; Magnetic Resonance Spectroscopy; Methylamines; Stereoisomerism

2003