n,n-dideethylchloroquine has been researched along with hydroxychloroquine in 6 studies
| Studies (n,n-dideethylchloroquine) | Trials (n,n-dideethylchloroquine) | Recent Studies (post-2010) (n,n-dideethylchloroquine) | Studies (hydroxychloroquine) | Trials (hydroxychloroquine) | Recent Studies (post-2010) (hydroxychloroquine) |
|---|---|---|---|---|---|
| 23 | 0 | 1 | 5,885 | 474 | 4,041 |
| Protein | Taxonomy | n,n-dideethylchloroquine (IC50) | hydroxychloroquine (IC50) |
|---|---|---|---|
| Muscarinic acetylcholine receptor M2 | Homo sapiens (human) | 2.951 | |
| Alpha-1D adrenergic receptor | Homo sapiens (human) | 4.772 | |
| Toll-like receptor 9 | Homo sapiens (human) | 0.11 | |
| Toll-like receptor 7 | Homo sapiens (human) | 3.4 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (16.67) | 18.7374 |
| 1990's | 3 (50.00) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Iredale, J; Wainer, IW | 1 |
| Khalil, SK; Miller, DR; Nygard, GA | 1 |
| Benziger, DP; Brown, RR; Stroshane, RM | 1 |
| Fieger, H; Iredale, J; Wainer, IW | 1 |
| Baethge, BA; Botstein, GR; Caldwell, J; Dietz, F; Ettlinger, R; Furst, DE; Gibbs, JP; Golden, HE; Lindsley, H; McLaughlin, GE; Moreland, LW; Munster, T; Roberts, WN; Rooney, TW; Rothschild, B; Sack, M; Sebba, AI; Shen, D; Weisman, M; Welch, KE; Yocum, D | 1 |
| Aweeka, F; Gingrich, D; Huang, L; Marzan, F; Sok, V | 1 |
6 other study(ies) available for n,n-dideethylchloroquine and hydroxychloroquine
| Article | Year |
|---|---|
Determination of hydroxychloroquine and its major metabolites in plasma using sequential achiral-chiral high-performance liquid chromatography.
Topics: Animals; Biological Availability; Chloroquine; Chromatography, High Pressure Liquid; Hydroxychloroquine; Male; Rabbits; Spectrophotometry, Ultraviolet; Stereoisomerism | 1992 |
Steady-state pharmacokinetics of hydroxychloroquine in rheumatoid arthritis patients.
Topics: Administration, Oral; Arthritis, Rheumatoid; Chloroquine; Female; Half-Life; Humans; Hydroxychloroquine; Male | 1991 |
High-performance liquid chromatographic assay for hydroxychloroquine and three of its major metabolites, desethylhydroxychloroquine, desethylchloroquine and bidesethylchloroquine, in human plasma.
Topics: Chloroquine; Chromatography, High Pressure Liquid; Freezing; Humans; Hydroxychloroquine | 1986 |
Enantioselective determination of hydroxychloroquine and its major metabolites in urine and the observation of a reversal in the (+)/(-)-hydroxychloroquine ratio.
Topics: Chloroquine; Chromatography, High Pressure Liquid; Humans; Hydroxychloroquine; Stereoisomerism | 1993 |
Hydroxychloroquine concentration-response relationships in patients with rheumatoid arthritis.
Topics: Adult; Antirheumatic Agents; Arthritis, Rheumatoid; Chloroquine; Eye Diseases; Gastrointestinal Diseases; Humans; Hydroxychloroquine; Logistic Models; Multicenter Studies as Topic; Oxidation-Reduction; Randomized Controlled Trials as Topic; Retrospective Studies; Severity of Illness Index | 2002 |
Development and validation of an LC-MS/MS method for determination of hydroxychloroquine, its two metabolites, and azithromycin in EDTA-treated human plasma.
Topics: Anti-Bacterial Agents; Antimalarials; Azithromycin; Blood Specimen Collection; Chloroquine; Chromatography, High Pressure Liquid; Drug Monitoring; Edetic Acid; Humans; Hydroxychloroquine; Limit of Detection; Tandem Mass Spectrometry | 2021 |