n,n-dideethylchloroquine has been researched along with desethylchloroquine in 18 studies
| Studies (n,n-dideethylchloroquine) | Trials (n,n-dideethylchloroquine) | Recent Studies (post-2010) (n,n-dideethylchloroquine) | Studies (desethylchloroquine) | Trials (desethylchloroquine) | Recent Studies (post-2010) (desethylchloroquine) |
|---|---|---|---|---|---|
| 23 | 0 | 1 | 126 | 14 | 16 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (44.44) | 18.7374 |
| 1990's | 7 (38.89) | 18.2507 |
| 2000's | 2 (11.11) | 29.6817 |
| 2010's | 1 (5.56) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
| Augustijns, P; Geusens, P; Verbeke, N | 1 |
| Iredale, J; Wainer, IW | 1 |
| Khalil, SK; Miller, DR; Nygard, GA | 1 |
| Augustijns, P; Jongsma, HW; Verbeke, N | 1 |
| Bourdon, R; Chevalier, P; Escande, C; Verdier, F | 1 |
| Ajayi, FO; Kuye, JO; Salako, LA | 2 |
| Ajayi, FO; Salako, LA | 1 |
| Benziger, DP; Brown, RR; Stroshane, RM | 1 |
| Aderounmu, AF | 1 |
| Bergqvist, Y; Eckerbom, S | 1 |
| Aderounmu, AF; Fleckenstein, L | 1 |
| Oosterhuis, B; Van Boxtel, CJ; Van den Berg, M; Wetsteyn, J | 1 |
| Fieger, H; Iredale, J; Wainer, IW | 1 |
| Brazier, JL; Chaulet, JF; Prevosto, JM; Robet, Y; Soares, O | 1 |
| Baethge, BA; Botstein, GR; Caldwell, J; Dietz, F; Ettlinger, R; Furst, DE; Gibbs, JP; Golden, HE; Lindsley, H; McLaughlin, GE; Moreland, LW; Munster, T; Roberts, WN; Rooney, TW; Rothschild, B; Sack, M; Sebba, AI; Shen, D; Weisman, M; Welch, KE; Yocum, D | 1 |
| Bagenda, D; Kalyesubula, I; Myers, C; Neely, M; Olness, K | 1 |
18 other study(ies) available for n,n-dideethylchloroquine and desethylchloroquine
| Article | Year |
|---|---|
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
Chloroquine levels in blood during chronic treatment of patients with rheumatoid arthritis.
Topics: Adult; Aged; Arthritis, Rheumatoid; Blood Proteins; Chloroquine; Female; Humans; Isomerism; Male; Middle Aged; Protein Binding; Retrospective Studies; Time Factors | 1992 |
Determination of hydroxychloroquine and its major metabolites in plasma using sequential achiral-chiral high-performance liquid chromatography.
Topics: Animals; Biological Availability; Chloroquine; Chromatography, High Pressure Liquid; Hydroxychloroquine; Male; Rabbits; Spectrophotometry, Ultraviolet; Stereoisomerism | 1992 |
Steady-state pharmacokinetics of hydroxychloroquine in rheumatoid arthritis patients.
Topics: Administration, Oral; Arthritis, Rheumatoid; Chloroquine; Female; Half-Life; Humans; Hydroxychloroquine; Male | 1991 |
Transplacental distribution of chloroquine in sheep.
Topics: Animals; Chloroquine; Female; Fetus; Half-Life; Injections, Intramuscular; Maternal-Fetal Exchange; Placenta; Pregnancy; Sheep | 1991 |
Sensitive radioimmunoassay and enzyme-linked immunosorbent assay for the simultaneous determination of chloroquine and its metabolites in biological fluids.
Topics: Animals; Chloroquine; Enzyme-Linked Immunosorbent Assay; Haptens; Humans; Indicators and Reagents; Iodine Radioisotopes; Polylysine; Rabbits; Radioimmunoassay; Swine | 1990 |
Comparison of the partitioning in vitro of chloroquine and its desethyl metabolites between the erythrocytes and plasma of healthy subjects and those with falciparum malaria.
Topics: Adolescent; Adult; Animals; Child; Chloroquine; Erythrocytes; Female; Humans; Kinetics; Malaria; Male; Plasma; Plasmodium falciparum; Time Factors | 1989 |
Distribution and urinary excretion of the desethylmetabolites of chloroquine in the rat.
Topics: Animals; Chloroquine; Dealkylation; Female; Male; Rats; Tissue Distribution | 1987 |
Antimalarial activity of bisdesethylchloroquine against P. falciparum and P. berghei berghei.
Topics: Animals; Chloroquine; Dose-Response Relationship, Drug; Drug Resistance, Microbial; Malaria; Mice; Plasmodium berghei; Plasmodium falciparum | 1987 |
High-performance liquid chromatographic assay for hydroxychloroquine and three of its major metabolites, desethylhydroxychloroquine, desethylchloroquine and bidesethylchloroquine, in human plasma.
Topics: Chloroquine; Chromatography, High Pressure Liquid; Freezing; Humans; Hydroxychloroquine | 1986 |
In vitro assessment of the antimalarial activity of chloroquine and its major metabolites.
Topics: Chloroquine; Drug Resistance, Microbial; Microbial Sensitivity Tests; Plasmodium falciparum | 1984 |
An improved gas chromatographic method for the simultaneous determination of chloroquine and two metabolites using capillary columns.
Topics: Biotransformation; Chloroquine; Chromatography, Gas; Humans | 1984 |
Pharmacokinetics of chloroquine diphosphate in the dog.
Topics: Absorption; Administration, Oral; Animals; Antimalarials; Chloroquine; Chromatography, Thin Layer; Dogs; Injections, Intravenous; Kinetics; Male | 1983 |
HPLC-analysis and preliminary pharmacokinetic parameter estimations of chloroquine.
Topics: Chloroquine; Chromatography, High Pressure Liquid; Half-Life; Humans; Kinetics; Labetalol | 1981 |
Enantioselective determination of hydroxychloroquine and its major metabolites in urine and the observation of a reversal in the (+)/(-)-hydroxychloroquine ratio.
Topics: Chloroquine; Chromatography, High Pressure Liquid; Humans; Hydroxychloroquine; Stereoisomerism | 1993 |
Simultaneous determination of chloroquine and quinine in human biological fluids by high-performance liquid chromatography.
Topics: Chloroquine; Chromatography, High Pressure Liquid; Erythrocytes; Humans; Indicators and Reagents; Plasma; Quinine; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet | 1993 |
Hydroxychloroquine concentration-response relationships in patients with rheumatoid arthritis.
Topics: Adult; Antirheumatic Agents; Arthritis, Rheumatoid; Chloroquine; Eye Diseases; Gastrointestinal Diseases; Humans; Hydroxychloroquine; Logistic Models; Multicenter Studies as Topic; Oxidation-Reduction; Randomized Controlled Trials as Topic; Retrospective Studies; Severity of Illness Index | 2002 |
Effect of chloroquine on human immunodeficiency virus (HIV) vertical transmission.
Topics: Animals; Antimalarials; Chloroquine; Chromatography, High Pressure Liquid; Cohort Studies; Female; Fetal Blood; HIV Infections; Humans; Infant, Newborn; Infectious Disease Transmission, Vertical; Malaria, Falciparum; Pregnancy; Pregnancy Complications, Infectious; Uganda | 2003 |