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n,n-di-n-propylserotonin and 8-hydroxy-2-(di-n-propylamino)tetralin

n,n-di-n-propylserotonin has been researched along with 8-hydroxy-2-(di-n-propylamino)tetralin in 2 studies

*8-Hydroxy-2-(di-n-propylamino)tetralin: A serotonin 1A-receptor agonist that is used experimentally to test the effects of serotonin. [MeSH]

Compound Research Comparison

Studies (n,n-di-n-propylserotonin)	Trials (n,n-di-n-propylserotonin)	Recent Studies (post-2010) (n,n-di-n-propylserotonin)	Studies (8-hydroxy-2-(di-n-propylamino)tetralin)	Trials (8-hydroxy-2-(di-n-propylamino)tetralin)	Recent Studies (post-2010) (8-hydroxy-2-(di-n-propylamino)tetralin)
12	1	7	3,530	7	389

Protein Interaction Comparison

Protein	Taxonomy	8-hydroxy-2-(di-n-propylamino)tetralin (IC50)
5-hydroxytryptamine receptor 1A	Homo sapiens (human)	0.0012
5-hydroxytryptamine receptor 1A	Rattus norvegicus (Norway rat)	0.0032
Alpha-2B adrenergic receptor	Rattus norvegicus (Norway rat)	0.81
D(2) dopamine receptor	Bos taurus (cattle)	0.8
Alpha-2C adrenergic receptor	Rattus norvegicus (Norway rat)	0.81
Alpha-2A adrenergic receptor	Rattus norvegicus (Norway rat)	0.81
D(2) dopamine receptor	Rattus norvegicus (Norway rat)	2.8959
Lysosomal alpha-glucosidase	Bos taurus (cattle)	0.0021

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	1 (50.00)	18.7374
1990's	1 (50.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Glennon, RA; Lyon, RA; Slusher, RM; Titeler, M	1
Barf, TA; de Boer, P; Ennis, MD; Ghazal, NB; McGuire, JC; Peroutka, SJ; Smith, MW; Swensson, K; Wikström, H	1

Other Studies

2 other study(ies) available for n,n-di-n-propylserotonin and 8-hydroxy-2-(di-n-propylamino)tetralin

Article	Year
N,N-di-n-propylserotonin: binding at serotonin binding sites and a comparison with 8-hydroxy-2-(di-n-propylamino)tetralin. Journal of medicinal chemistry, 1988, Volume: 31, Issue:4 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Binding Sites; Discrimination Learning; Male; Naphthalenes; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Tetrahydronaphthalenes	1988
5-HT1D receptor agonist properties of novel 2-[5-[[(trifluoromethyl)sulfonyl]oxy]indolyl]ethylamines and their use as synthetic intermediates. Journal of medicinal chemistry, 1996, Nov-22, Volume: 39, Issue:24 Topics: 5-Hydroxytryptophan; Acrylamides; Animals; Brain; CHO Cells; Cricetinae; Cyclic AMP; Ethylamines; Guinea Pigs; Humans; Hydroxyindoleacetic Acid; Hypothermia; Magnetic Resonance Spectroscopy; Mass Spectrometry; Molecular Structure; Rats; Receptors, Serotonin; Recombinant Proteins; Serotonin; Serotonin Antagonists; Structure-Activity Relationship	1996

Article

Year

N,N-di-n-propylserotonin: binding at serotonin binding sites and a comparison with 8-hydroxy-2-(di-n-propylamino)tetralin.

Journal of medicinal chemistry, 1988, Volume: 31, Issue:4

Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Binding Sites; Discrimination Learning; Male; Naphthalenes; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Tetrahydronaphthalenes

1988

5-HT1D receptor agonist properties of novel 2-[5-[[(trifluoromethyl)sulfonyl]oxy]indolyl]ethylamines and their use as synthetic intermediates.

Journal of medicinal chemistry, 1996, Nov-22, Volume: 39, Issue:24

Topics: 5-Hydroxytryptophan; Acrylamides; Animals; Brain; CHO Cells; Cricetinae; Cyclic AMP; Ethylamines; Guinea Pigs; Humans; Hydroxyindoleacetic Acid; Hypothermia; Magnetic Resonance Spectroscopy; Mass Spectrometry; Molecular Structure; Rats; Receptors, Serotonin; Recombinant Proteins; Serotonin; Serotonin Antagonists; Structure-Activity Relationship

1996