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n,n'-diphenyl-4-phenylenediamine and deferoxamine

n,n'-diphenyl-4-phenylenediamine has been researched along with deferoxamine in 26 studies

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-19906 (23.08)18.7374
1990's18 (69.23)18.2507
2000's2 (7.69)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Farber, JL; Yamamoto, K1
Autor, AP; Thies, RL1
Farber, JL; Harman, AW; Kyle, ME; Serroni, A1
Casini, AF; Coleman, JB; Farber, JL; Serroni, A1
Brown, PC; Chen, Q; Jones, TW; Stevens, JL1
Farber, JL; Kyle, ME; Sakaida, I; Serroni, A1
Farber, JL; Kyle, ME; Nakae, D; Sakaida, S; Serroni, A1
Reed, DJ; Thomas, CE1
Farber, JL; Kyle, ME; Nakae, D; Serroni, A1
Cohen, P; Di Monte, D; Sandy, MS; Smith, MT1
Farber, JL; Gilfor, D; Kyle, ME; Miccadei, S; Nakae, D1
Ellen, JM; Farber, JL; Gerson, RJ; Gilfor, D; Serroni, A1
Farber, JL; Gilfor, E; Glascott, PA1
Iesaki, T; Ochi, R; Okada, T; Yamaguchi, H1
de Bont, HJ; Mulder, GJ; Nagelkerke, JF; van de Water, B; Zoeteweij, JP1
Brunk, UT; Ollinger, K1
Roeser, NF; Sogabe, K; Venkatachalam, MA; Weinberg, JM1
Cenas, N; Dickancaite, E; Kalvelyte, A; Serapiniene, N1
Byrne, AM; Herman, B; Lemasters, JJ; Nieminen, AL1
Cederbaum, AI; Chen, Q; Galleano, M1
Anusevicius, Z; Cenas, N; Dickancaite, E; Nemeikaite, A; Nivinskas, H; Sarlauskas, J; Segura-Aguilar, J1
Cènas, N; Dickancaité, E; Kalvelytè, A; Nemeikaitè, A1
Furuno, K; Shimomichi, K; Suetsugu, T; Sugihara, N; Tsuruta, Y1
Ball, JG; Harmon, RC; Hong, SK; Meadows, MK; Rankin, GO; Valentovic, M1
Anusevicius, Z; Cenas, N; Nemeikaite-Ceniene, A; Nivinskas, H; Sarlauskas, J1
Cummings, BS; Gelasco, AK; Kinsey, GR; McHowat, J; Schnellmann, RG1

Other Studies

26 other study(ies) available for n,n'-diphenyl-4-phenylenediamine and deferoxamine

ArticleYear
Metabolism of pyridine nucleotides in cultured rat hepatocytes intoxicated with tert-butyl hydroperoxide.
    Biochemical pharmacology, 1992, Mar-03, Volume: 43, Issue:5

    Topics: Animals; Benzamides; Carmustine; Cell Death; Cells, Cultured; Deferoxamine; Drug Interactions; Hydrogen Peroxide; Liver; Male; NAD; NADP; Peroxides; Phenylenediamines; Rats; Rats, Inbred Strains; tert-Butylhydroperoxide; Time Factors

1992
Reactive oxygen injury to cultured pulmonary artery endothelial cells: mediation by poly(ADP-ribose) polymerase activation causing NAD depletion and altered energy balance.
    Archives of biochemistry and biophysics, 1991, May-01, Volume: 286, Issue:2

    Topics: Adenine Nucleotides; Animals; Antioxidants; Catalase; Cattle; Cell Survival; Cells, Cultured; Deferoxamine; Endothelium, Vascular; Energy Metabolism; Enzyme Activation; Free Radicals; Fumarates; Hydrogen Peroxide; Kinetics; NAD; Oxygen; Phenylenediamines; Poly(ADP-ribose) Polymerases; Pulmonary Artery; Superoxide Dismutase; Superoxides

1991
The killing of cultured hepatocytes by N-acetyl-p-benzoquinone imine (NAPQI) as a model of the cytotoxicity of acetaminophen.
    Biochemical pharmacology, 1991, Apr-15, Volume: 41, Issue:8

    Topics: Acetaminophen; Acidosis; Adenosine Triphosphate; Animals; Benzoflavones; Benzoquinones; beta-Naphthoflavone; Carmustine; Cell Survival; Cells, Cultured; Deferoxamine; Glutathione; Glutathione Reductase; Imines; In Vitro Techniques; Liver; Models, Biological; Monensin; Oxidation-Reduction; Phenylenediamines; Rats

1991
Evidence for the participation of activated oxygen species and the resulting peroxidation of lipids in the killing of cultured hepatocytes by aryl halides.
    Toxicology and applied pharmacology, 1990, Sep-15, Volume: 105, Issue:3

    Topics: Animals; Bromobenzenes; Carmustine; Cell Survival; Cells, Cultured; Chlorobenzenes; Deferoxamine; Hydrogen Peroxide; Iodobenzenes; Lipid Peroxidation; Liver; Male; Oxygen; Phenylenediamines; Pyridines; Rats; Rats, Inbred Strains

1990
The mechanism of cysteine conjugate cytotoxicity in renal epithelial cells. Covalent binding leads to thiol depletion and lipid peroxidation.
    The Journal of biological chemistry, 1990, Dec-15, Volume: 265, Issue:35

    Topics: Animals; Antioxidants; Carbon-Sulfur Lyases; Cell Line; Cell Survival; Cysteine; Deferoxamine; Dithiothreitol; Epithelium; In Vitro Techniques; Kidney; Lipid Peroxides; Lyases; Phenylenediamines; Rats; Sulfhydryl Compounds

1990
Metabolism of acetaminophen by cultured rat hepatocytes. Depletion of protein thiol groups without any loss of viability.
    Biochemical pharmacology, 1990, Sep-15, Volume: 40, Issue:6

    Topics: Acetaminophen; Animals; Carmustine; Cells, Cultured; Deferoxamine; Glutathione; Glutathione Disulfide; Liver; Male; Phenylenediamines; Proteins; Rats; Rats, Inbred Strains; Sulfhydryl Compounds

1990
Protein thiol depletion and the killing of cultured hepatocytes by hydrogen peroxide.
    Biochemical pharmacology, 1989, Nov-01, Volume: 38, Issue:21

    Topics: Animals; Cell Survival; Cells, Cultured; Deferoxamine; Disulfides; Ferric Compounds; Glucose Oxidase; Glutathione; Glutathione Disulfide; Hydrogen Peroxide; Iron Chelating Agents; Lipid Peroxides; Liver; Male; Oxidation-Reduction; Phenylenediamines; Rats; Rats, Inbred Strains; Vitamin K

1989
Effect of extracellular Ca++ omission on isolated hepatocytes. I. Induction of oxidative stress and cell injury.
    The Journal of pharmacology and experimental therapeutics, 1988, Volume: 245, Issue:2

    Topics: Animals; Antioxidants; Calcium; Cells, Cultured; Deferoxamine; Egtazic Acid; Kinetics; L-Lactate Dehydrogenase; Liver; Male; Malondialdehyde; Phenylenediamines; Rats; Rats, Inbred Strains

1988
1,3-(2-Chloroethyl)-1-nitrosourea potentiates the toxicity of acetaminophen both in the phenobarbital-induced rat and in hepatocytes cultured from such animals.
    Molecular pharmacology, 1988, Volume: 34, Issue:4

    Topics: Acetaminophen; Acetone; Carmustine; Cell Survival; Deferoxamine; Drug Synergism; Enzyme Induction; Glutathione; Liver; Male; Maleates; Methylcholanthrene; Phenobarbital; Phenylenediamines

1988
Role of active oxygen in paraquat and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) cytotoxicity.
    Basic life sciences, 1988, Volume: 49

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Antioxidants; Carmustine; Cell Survival; Cells, Cultured; Deferoxamine; Free Radicals; Lipid Peroxidation; Liver; Paraquat; Phenylenediamines; Pyridines; Rats; Reference Values; Vitamin E

1988
Oxidative cell injury in the killing of cultured hepatocytes by allyl alcohol.
    Archives of biochemistry and biophysics, 1988, Volume: 265, Issue:2

    Topics: 1-Propanol; Acrolein; Animals; Cell Survival; Cells, Cultured; Deferoxamine; Drug Interactions; Glutathione; Glutathione Transferase; Lipid Peroxides; Liver; Male; Oxidation-Reduction; Phenylenediamines; Propanols; Rats; Rats, Inbred Strains

1988
Killing of cultured hepatocytes by the mixed-function oxidation of ethoxycoumarin.
    Biochemical pharmacology, 1986, Dec-01, Volume: 35, Issue:23

    Topics: Animals; Carmustine; Cell Survival; Cells, Cultured; Coumarins; Deferoxamine; Glutathione; Glutathione Reductase; Iron; Lipid Peroxides; Liver; Oxidation-Reduction; Phenylenediamines; Proadifen; Rats; Rats, Inbred Strains

1986
Relationship of the metabolism of vitamins C and E in cultured hepatocytes treated with tert-butyl hydroperoxide.
    Molecular pharmacology, 1995, Volume: 48, Issue:1

    Topics: Animals; Antioxidants; Ascorbic Acid; Cells, Cultured; Deferoxamine; DNA Damage; DNA, Single-Stranded; Lipid Peroxidation; Liver; Male; Peroxides; Phenylenediamines; Rats; Rats, Sprague-Dawley; tert-Butylhydroperoxide; Vitamin E

1995
Inhibition of vasoactive amine induced contractions of vascular smooth muscle by hydrogen peroxide in rabbit aorta.
    Cardiovascular research, 1994, Volume: 28, Issue:7

    Topics: Acetylcholine; Animals; Antioxidants; Aorta; Deferoxamine; Depression, Chemical; Endothelium, Vascular; Hydrogen Peroxide; In Vitro Techniques; Indomethacin; Male; Muscle Contraction; Muscle, Smooth, Vascular; Phenylenediamines; Phenylephrine; Potassium; Rabbits

1994
Role of mitochondrial Ca2+ in the oxidative stress-induced dissipation of the mitochondrial membrane potential. Studies in isolated proximal tubular cells using the nephrotoxin 1,2-dichlorovinyl-L-cysteine.
    The Journal of biological chemistry, 1994, May-20, Volume: 269, Issue:20

    Topics: Animals; Antioxidants; Benzene Derivatives; Calcium; Cysteine; Deferoxamine; Egtazic Acid; Flow Cytometry; In Vitro Techniques; Intracellular Membranes; Kidney Tubules, Proximal; Kinetics; Male; Membrane Potentials; Mitochondria; Oxygen; Phenylenediamines; Rats; Rats, Wistar

1994
Cellular injury induced by oxidative stress is mediated through lysosomal damage.
    Free radical biology & medicine, 1995, Volume: 19, Issue:5

    Topics: Adenosine Triphosphate; Animals; Antineoplastic Agents; Antioxidants; Calcium; Cell Survival; Cells, Cultured; Cytochalasin B; Cytosol; Deferoxamine; Endocytosis; Glutathione; Iron Chelating Agents; Kinetics; Liver; Lysosomes; Male; Monensin; Naphthoquinones; Oxidative Stress; Phenylenediamines; Rats; Rats, Wistar; Time Factors

1995
Differential cytoprotection by glycine against oxidant damage to proximal tubule cells.
    Kidney international, 1996, Volume: 50, Issue:3

    Topics: Animals; Antioxidants; Cell Hypoxia; Cells, Cultured; Deferoxamine; Female; Glycine; Hemostatics; Hydroxyquinolines; Iron; Kidney Tubules, Proximal; Lipid Peroxidation; Oxidative Stress; Peroxides; Phenylenediamines; Rabbits; Reactive Oxygen Species; Siderophores; tert-Butylhydroperoxide; Vitamin K

1996
Toxicity of daunorubicin and naphthoquinones to HL-60 cells: an involvement of oxidative stress.
    Biochemistry and molecular biology international, 1997, Volume: 41, Issue:5

    Topics: Antibiotics, Antineoplastic; Antioxidants; Apoptosis; Benzoquinones; Cell Survival; Daunorubicin; Deferoxamine; HL-60 Cells; Humans; Iron Chelating Agents; Naphthoquinones; Oxidative Stress; Phenylenediamines

1997
Mitochondrial permeability transition in hepatocytes induced by t-BuOOH: NAD(P)H and reactive oxygen species.
    The American journal of physiology, 1997, Volume: 272, Issue:4 Pt 1

    Topics: Animals; Antioxidants; Cells, Cultured; Deferoxamine; Liver; Male; Mitochondria, Liver; NAD; NADP; Oxidation-Reduction; Permeability; Peroxides; Phenylenediamines; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; tert-Butylhydroperoxide; Trifluoperazine

1997
Cytotoxicity and apoptosis produced by arachidonic acid in Hep G2 cells overexpressing human cytochrome P4502E1.
    The Journal of biological chemistry, 1997, Jun-06, Volume: 272, Issue:23

    Topics: alpha-Tocopherol; Antioxidants; Apoptosis; Ascorbic Acid; Aspirin; Carcinoma, Hepatocellular; Cell Survival; Chromans; Cytochrome P-450 CYP2E1; Deferoxamine; Humans; L-Lactate Dehydrogenase; Liver Neoplasms; Oleic Acid; Phenylenediamines; Propyl Gallate; Proto-Oncogene Proteins c-bcl-2; Recombinant Proteins; Transfection; Tumor Cells, Cultured; Vitamin E

1997
Nitrobenzimidazoles as substrates for DT-diaphorase and redox cycling compounds: their enzymatic reactions and cytotoxicity.
    Archives of biochemistry and biophysics, 1997, Oct-15, Volume: 346, Issue:2

    Topics: Animals; Antioxidants; Benzimidazoles; Cell Line, Transformed; Cell Survival; Deferoxamine; Enzyme Inhibitors; Kidney; Kinetics; Liver; Molecular Structure; NAD(P)H Dehydrogenase (Quinone); NADP; Nitro Compounds; Phenylenediamines; Rats; Sheep; Spectrophotometry; Substrate Specificity

1997
Prooxidant character of flavonoid cytotoxicity: structure-activity relationships.
    Biochemistry and molecular biology international, 1998, Volume: 45, Issue:5

    Topics: Animals; Antioxidants; Cell Death; Cell Line, Transformed; Chelating Agents; Deferoxamine; Flavonoids; HL-60 Cells; Humans; Lipid Peroxidation; Malondialdehyde; Oxidants; Oxidation-Reduction; Oxidative Stress; Phenylenediamines; Sheep; Structure-Activity Relationship

1998
Lipid peroxidation induced by adriamycin in linolenic acid-loaded cultured hepatocytes.
    Pharmacology & toxicology, 1998, Volume: 83, Issue:4

    Topics: 7-Alkoxycoumarin O-Dealkylase; alpha-Linolenic Acid; Animals; Antibiotics, Antineoplastic; Antioxidants; Cells, Cultured; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Deferoxamine; Dose-Response Relationship, Drug; Doxorubicin; Enzyme Inhibitors; L-Lactate Dehydrogenase; Lipid Peroxidation; Liver; Male; Malondialdehyde; Phenylenediamines; Proadifen; Rats; Rats, Wistar; Vitamin E

1998
2-Amino-5-chlorophenol toxicity in renal cortical slices from Fischer 344 rats: effect of antioxidants and sulfhydryl agents.
    Toxicology and applied pharmacology, 1999, Nov-15, Volume: 161, Issue:1

    Topics: Animals; Antioxidants; Ascorbic Acid; Buthionine Sulfoximine; Chlorophenols; Deferoxamine; Dithiothreitol; Dose-Response Relationship, Drug; Free Radicals; Gluconeogenesis; Glutathione; In Vitro Techniques; Iron; Iron Chelating Agents; Kidney Cortex; Lipid Peroxidation; Male; Phenylenediamines; Pyruvic Acid; Rats; Rats, Inbred F344; Sulfhydryl Reagents

1999
Cytotoxicity of RH1 and related aziridinylbenzoquinones: involvement of activation by NAD(P)H:quinone oxidoreductase (NQO1) and oxidative stress.
    Archives of biochemistry and biophysics, 2003, Aug-01, Volume: 416, Issue:1

    Topics: Animals; Antioxidants; Aziridines; Benzoquinones; Cells, Cultured; Deferoxamine; Dicumarol; Enzyme Activation; Fibroblasts; Lipid Peroxidation; NAD(P)H Dehydrogenase (Quinone); NADP; NADPH-Ferrihemoprotein Reductase; Oxidative Stress; Phenylenediamines; Structure-Activity Relationship; Toxicity Tests

2003
Inactivation of endoplasmic reticulum bound Ca2+-independent phospholipase A2 in renal cells during oxidative stress.
    Journal of the American Society of Nephrology : JASN, 2004, Volume: 15, Issue:6

    Topics: Animals; Annexin A5; Antioxidants; Butylated Hydroxytoluene; Carbon; Cells, Cultured; Chelating Agents; Deferoxamine; Dithiothreitol; Dose-Response Relationship, Drug; Electron Spin Resonance Spectroscopy; Endoplasmic Reticulum; Female; Free Radicals; Group VI Phospholipases A2; Iron Chelating Agents; Kidney; Kidney Tubules; Magnetics; Microsomes; Naphthalenes; Oxidants; Oxidative Stress; Phenylenediamines; Phosphodiesterase Inhibitors; Phospholipases A; Phospholipases A2; Phospholipids; Pyrones; Rabbits; Reactive Oxygen Species; tert-Butylhydroperoxide; Time Factors

2004