n,n'-bis(2-hydroxybenzyl)ethylenediamine-n,n'-diacetic acid has been researched along with deferoxamine in 15 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (33.33) | 18.7374 |
| 1990's | 6 (40.00) | 18.2507 |
| 2000's | 4 (26.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bao, Y; Metterville, J; Pitt, CG; Rosenkrantz, H; Thompson, J; Wani, MC | 1 |
| Faller, B; Wohnsland, F | 1 |
| Chitambar, CR; Lundberg, JH | 1 |
| Chew, BP; Tanaka, TS; Tjoelker, LW | 1 |
| Cerny, EA; Lau, EH; Rahman, YE; Wright, BJ | 1 |
| Carnes, BA; Cerny, EA; Lau, EH; Rahman, YE | 1 |
| Grady, RW; Hershko, C; Link, G | 1 |
| Giardina, PJ; Grady, RW; Hilgartner, MW; Salbe, AD | 1 |
| Hider, RC; Tilbrook, GS | 1 |
| Bergeron, RJ; Brittenham, GM; Wiegand, J | 3 |
| Hershko, C; Konijn, AM; Link, G | 1 |
| Cook, J | 1 |
| Cunningham, S; Hillard, CJ; Kalivendi, SV; Kalyanaraman, B; Kotamraju, S; Shang, T | 1 |
2 review(s) available for n,n'-bis(2-hydroxybenzyl)ethylenediamine-n,n'-diacetic acid and deferoxamine
| Article | Year |
|---|---|
Iron chelators for clinical use.
Topics: Biological Transport; Deferoxamine; Drug Delivery Systems; Edetic Acid; Ferric Compounds; Free Radical Scavengers; Humans; Iron; Iron Chelating Agents; Iron Overload; Ligands; Molecular Weight; Oxidation-Reduction; Pentetic Acid; Razoxane; Solubility; Structure-Activity Relationship; Tissue Distribution | 1998 |
Iron chelators for thalassaemia.
Topics: Administration, Oral; Aza Compounds; Chelating Agents; Deferiprone; Deferoxamine; Edetic Acid; Humans; Iron; Iron Chelating Agents; Iron Overload; Long-Term Care; Pyridones; Thalassemia | 1998 |
1 trial(s) available for n,n'-bis(2-hydroxybenzyl)ethylenediamine-n,n'-diacetic acid and deferoxamine
| Article | Year |
|---|---|
Results from a phase I clinical trial of HBED.
Topics: Adolescent; Adult; beta-Thalassemia; Chelating Agents; Deferoxamine; Edetic Acid; Female; Humans; Iron; Male; Transfusion Reaction | 1994 |
12 other study(ies) available for n,n'-bis(2-hydroxybenzyl)ethylenediamine-n,n'-diacetic acid and deferoxamine
| Article | Year |
|---|---|
Esters and lactones of phenolic amino carboxylic acids: prodrugs for iron chelation.
Topics: Animals; Blood Transfusion; Carboxylic Acids; Erythrocyte Transfusion; Esters; Hydrolysis; Indicators and Reagents; Iron; Iron Chelating Agents; Lactones; Liver; Magnetic Resonance Spectroscopy; Mice; Spectrophotometry, Infrared; Spleen; Structure-Activity Relationship | 1986 |
High-throughput permeability pH profile and high-throughput alkane/water log P with artificial membranes.
Topics: Alkanes; Humans; Hydrogen-Ion Concentration; Intestinal Absorption; Membranes, Artificial; Octanols; Permeability; Pharmaceutical Preparations; Solubility; Water | 2001 |
Interaction of gallium nitrate with fludarabine and iron chelators: effects on the proliferation of human leukemic HL60 cells.
Topics: Antineoplastic Agents; Cell Division; Deferoxamine; Drug Synergism; Edetic Acid; Gallium; Humans; Iron; Iron Chelating Agents; Leukemia, Promyelocytic, Acute; Tumor Cells, Cultured; Vidarabine Phosphate | 1990 |
In vitro growth inhibition of mastitis causing bacteria by phenolics and metal chelators.
Topics: Animals; Butylated Hydroxyanisole; Butylated Hydroxytoluene; Cattle; Chelating Agents; Deferoxamine; Edetic Acid; Escherichia coli; Ethylenediamines; Female; Hydroquinones; In Vitro Techniques; Klebsiella pneumoniae; Mastitis, Bovine; Pentetic Acid; Phenols; Staphylococcus aureus; Streptococcus agalactiae | 1985 |
Improvement of iron removal from the reticuloendothelial system by liposome encapsulation of N,N'-bis[2-hydroxybenzyl]-ethylenediamine-N,N'-diacetic acid (HBED). Comparison with desferrioxamine.
Topics: Animals; Bile; Bile Canaliculi; Chelating Agents; Deferoxamine; Edetic Acid; Feces; Female; Iron; Kupffer Cells; Liposomes; Liver; Mice; Microscopy, Electron; Mononuclear Phagocyte System; Tissue Distribution | 1983 |
Enhanced iron removal from liver parenchymal cells in experimental iron overload: liposome encapsulation of HBED and phenobarbital administration.
Topics: Animals; Deferoxamine; Edetic Acid; Feces; Ferritins; Iron; Liposomes; Liver; Mice; Phenobarbital | 1983 |
Development and evaluation of the improved iron chelating agents EHPG, HBED and their dimethyl esters.
Topics: Administration, Oral; Animals; Deferoxamine; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Interactions; Edetic Acid; Ethylenediamines; Female; Infusions, Parenteral; Iron Chelating Agents; Iron Radioisotopes; Rats; Rats, Inbred Strains; Transfusion Reaction | 1984 |
HBED: A potential alternative to deferoxamine for iron-chelating therapy.
Topics: Animals; Antidotes; Chelating Agents; Deferoxamine; Edetic Acid; Haplorhini; Iron Overload; Male; Rats; Rats, Sprague-Dawley; Transfusion Reaction | 1998 |
HBED: the continuing development of a potential alternative to deferoxamine for iron-chelating therapy.
Topics: Administration, Oral; Animals; Cebus; Deferoxamine; Edetic Acid; Injections, Intravenous; Injections, Subcutaneous; Iron; Iron Chelating Agents; Iron Overload; Iron-Dextran Complex; Male; Rats; Rats, Sprague-Dawley | 1999 |
Radiation sensitization of mammalian cells by metal chelators.
Topics: Animals; Cell Cycle; Chelating Agents; Colony-Forming Units Assay; Cricetinae; Cricetulus; Deferiprone; Deferoxamine; DNA Replication; Edetic Acid; Fibroblasts; Genes, p53; Humans; Iron Chelating Agents; Lung; Lung Neoplasms; Mimosine; Pyridones; Radiation-Sensitizing Agents; S Phase; Tumor Cells, Cultured | 2001 |
HBED ligand: preclinical studies of a potential alternative to deferoxamine for treatment of chronic iron overload and acute iron poisoning.
Topics: Acute Disease; Animals; Blood Pressure; Cebus; Chronic Disease; Deferoxamine; Disease Models, Animal; Dogs; Drug Administration Routes; Drug Evaluation, Preclinical; Edetic Acid; Heart Rate; Iron; Iron Chelating Agents; Iron Overload; Male; Poisoning; Rats; Rats, Sprague-Dawley; Therapeutic Equivalency | 2002 |
1-Methyl-4-phenylpyridinium (MPP+)-induced apoptosis and mitochondrial oxidant generation: role of transferrin-receptor-dependent iron and hydrogen peroxide.
Topics: 1-Methyl-4-phenylpyridinium; Aconitate Hydratase; Animals; Antioxidants; Apoptosis; Caspase 3; Caspases; Cells, Cultured; Deferoxamine; Edetic Acid; Female; Glutathione Peroxidase; Glutathione Peroxidase GPX1; Humans; Hydrogen Peroxide; Iron; Iron Chelating Agents; Male; Metalloporphyrins; Mitochondria; NADH, NADPH Oxidoreductases; Neurons; Oxidants; Oxidative Stress; Parkinson Disease; Reactive Oxygen Species; Receptors, Transferrin; Staining and Labeling; Transferrin | 2003 |