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n,n'-bis(1-decylnipecotoyl)piperazine and alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid

n,n'-bis(1-decylnipecotoyl)piperazine has been researched along with alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid in 1 studies

*alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid: An IBOTENIC ACID homolog and glutamate agonist. The compound is the defining agonist for the AMPA subtype of glutamate receptors (RECEPTORS, AMPA). It has been used as a radionuclide imaging agent but is more commonly used as an experimental tool in cell biological studies. [MeSH]

*alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid: An IBOTENIC ACID homolog and glutamate agonist. The compound is the defining agonist for the AMPA subtype of glutamate receptors (RECEPTORS, AMPA). It has been used as a radionuclide imaging agent but is more commonly used as an experimental tool in cell biological studies. [MeSH]

Compound Research Comparison

Studies
(n,n'-bis(1-decylnipecotoyl)piperazine)
Trials
(n,n'-bis(1-decylnipecotoyl)piperazine)
Recent Studies (post-2010)
(n,n'-bis(1-decylnipecotoyl)piperazine)
Studies
(alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid)
Trials
(alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid)
Recent Studies (post-2010) (alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid)
7002,89911609

Protein Interaction Comparison

ProteinTaxonomyn,n'-bis(1-decylnipecotoyl)piperazine (IC50)alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (IC50)
Glutamate receptor 1Rattus norvegicus (Norway rat)0.157
Glutamate receptor 2Rattus norvegicus (Norway rat)0.1765
Glutamate receptor 3Rattus norvegicus (Norway rat)0.1765
Glutamate receptor 4Rattus norvegicus (Norway rat)0.1765
Glutamate receptor 1Mus musculus (house mouse)0.04
Glutamate receptor 2Mus musculus (house mouse)0.04
Glutamate receptor 1Homo sapiens (human)0.1353
Glutamate receptor 2Homo sapiens (human)0.1353
Glutamate receptor 3Homo sapiens (human)0.1353
Glutamate receptor 4Homo sapiens (human)0.1353
Glutamate receptor 4Mus musculus (house mouse)0.04
Glutamate receptor 3Mus musculus (house mouse)0.04

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bahr, BA; Munirathinam, S1

Other Studies

1 other study(ies) available for n,n'-bis(1-decylnipecotoyl)piperazine and alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid

ArticleYear
Repeated contact with subtoxic soman leads to synaptic vulnerability in hippocampus.
    Journal of neuroscience research, 2004, Sep-01, Volume: 77, Issue:5

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Blotting, Western; Brain Diseases; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Excitatory Amino Acid Agonists; Gene Expression Regulation; Hippocampus; Nipecotic Acids; Organ Culture Techniques; Piperazines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Soman; Staining and Labeling; Synapses; Synaptophysin; Trimethyltin Compounds

2004