Page last updated: 2024-08-25

n-methylscopolamine and strychnine

n-methylscopolamine has been researched along with strychnine in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19901 (9.09)18.7374
1990's7 (63.64)18.2507
2000's3 (27.27)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Birdsall, NJ; Lazareno, S1
Bacáková, L; El-Fakahany, EE; Jakubík, J; Tucek, S1
Kuhar, MJ; Price, DL; Tourtellotte, WW; Wamsley, JK; Whitehouse, PJ; Zarbin, MA1
Proska, J; Tucek, S2
Birdsall, NJ; Gharagozloo, P; Kuonen, D; Lazareno, S; Popham, A1
Birdsall, NJ; Gharagozloo, P; Lazareno, S; Popham, A1
Birdsall, B; Birdsall, NJ; Fukazawa, T; Gharagozloo, P; Hashimoto, T; Kuwano, H; Lazareno, S; Popham, A; Sugimoto, M1
Havlas, Z; Lysíková, M; Tucek, S1
Buller, S; Holzgrabe, U; Mohr, K; Zlotos, DP1
Dolezal, V; Jakubík, J1

Other Studies

11 other study(ies) available for n-methylscopolamine and strychnine

ArticleYear
Detection, quantitation, and verification of allosteric interactions of agents with labeled and unlabeled ligands at G protein-coupled receptors: interactions of strychnine and acetylcholine at muscarinic receptors.
    Molecular pharmacology, 1995, Volume: 48, Issue:2

    Topics: Acetylcholine; Allosteric Regulation; Animals; CHO Cells; Cloning, Molecular; Cricetinae; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Ligands; Radioligand Assay; Receptors, Muscarinic; Strychnine

1995
Positive cooperativity of acetylcholine and other agonists with allosteric ligands on muscarinic acetylcholine receptors.
    Molecular pharmacology, 1997, Volume: 52, Issue:1

    Topics: Acetylcholine; Allosteric Regulation; Animals; Binding, Competitive; CHO Cells; Cricetinae; Ligands; Muscarinic Agonists; N-Methylscopolamine; Receptors, Muscarinic; Scopolamine Derivatives

1997
Amyotrophic lateral sclerosis: alterations in neurotransmitter receptors.
    Annals of neurology, 1983, Volume: 14, Issue:1

    Topics: Adult; Aged; Amyotrophic Lateral Sclerosis; Autoradiography; Female; Flunitrazepam; Humans; Male; Middle Aged; Motor Neurons; N-Methylscopolamine; Nerve Degeneration; Neurotransmitter Agents; Receptors, Cell Surface; Receptors, GABA-A; Receptors, Glycine; Receptors, Muscarinic; Receptors, Neurotransmitter; Scopolamine Derivatives; Spinal Cord; Strychnine

1983
Competition between positive and negative allosteric effectors on muscarinic receptors.
    Molecular pharmacology, 1995, Volume: 48, Issue:4

    Topics: Alcuronium; Allosteric Site; Animals; Binding, Competitive; Gallamine Triethiodide; Kinetics; Mathematical Computing; Models, Biological; Myocardium; N-Methylscopolamine; Nicotinic Antagonists; Poisons; Radioligand Assay; Rats; Receptors, Muscarinic; Scopolamine Derivatives; Strychnine; Tritium

1995
Positive allosteric action of eburnamonine on cardiac muscarinic acetylcholine receptors.
    European journal of pharmacology, 1996, Jun-03, Volume: 305, Issue:1-3

    Topics: Alcuronium; Allosteric Regulation; Animals; Cholinergic Agonists; Heart Atria; In Vitro Techniques; Male; N-Methylscopolamine; Nicotinic Antagonists; Parasympatholytics; Protein Binding; Rats; Receptors, Cholinergic; Scopolamine Derivatives; Strychnine; Vinca Alkaloids; Vincamine

1996
Subtype-selective positive cooperative interactions between brucine analogues and acetylcholine at muscarinic receptors: radioligand binding studies.
    Molecular pharmacology, 1998, Volume: 53, Issue:3

    Topics: Acetylcholine; Allosteric Regulation; Animals; CHO Cells; Cricetinae; N-Methylscopolamine; Radioligand Assay; Receptors, Muscarinic; Strychnine

1998
Allosteric interactions of quaternary strychnine and brucine derivatives with muscarinic acetylcholine receptors.
    Journal of medicinal chemistry, 1999, Feb-11, Volume: 42, Issue:3

    Topics: Allosteric Regulation; Animals; CHO Cells; Cricetinae; Humans; Muscarinic Antagonists; N-Methylscopolamine; Receptors, Muscarinic; Structure-Activity Relationship; Strychnine

1999
Allosteric effects of four stereoisomers of a fused indole ring system with 3H-N-methylscopolamine and acetylcholine at M1-M4 muscarinic receptors.
    Life sciences, 1999, Volume: 64, Issue:6-7

    Topics: Acetylcholine; Allosteric Regulation; Allosteric Site; Animals; Cell Membrane; CHO Cells; Cricetinae; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Humans; Indoles; Kinetics; Muscarinic Agonists; Muscarinic Antagonists; N-Methylscopolamine; Propylbenzilylcholine Mustard; Receptors, Muscarinic; Stereoisomerism; Strychnine; Thermodynamics

1999
Interactions between allosteric modulators and 4-DAMP and other antagonists at muscarinic receptors: potential significance of the distance between the N and carboxyl C atoms in the molecules of antagonists.
    Neurochemical research, 2001, Volume: 26, Issue:4

    Topics: Alcuronium; Allosteric Regulation; Animals; CHO Cells; Cricetinae; Muscarinic Antagonists; N-Methylscopolamine; Piperidines; Radioligand Assay; Strychnine; Tritium

2001
Bisquaternary dimers of strychnine and brucine. A new class of potent enhancers of antagonist binding to muscarinic M2 receptors.
    Bioorganic & medicinal chemistry, 2003, Jun-12, Volume: 11, Issue:12

    Topics: Allosteric Regulation; Animals; Dimerization; Molecular Conformation; Muscarinic Antagonists; N-Methylscopolamine; Radioligand Assay; Receptor, Muscarinic M2; Structure-Activity Relationship; Strychnine; Swine

2003
Determinants of positive cooperativity between strychnine-like allosteric modulators and N-methylscopolamine at muscarinic receptors.
    Journal of molecular neuroscience : MN, 2006, Volume: 30, Issue:1-2

    Topics: Allosteric Regulation; Amino Acid Substitution; Asparagine; Mutagenesis, Site-Directed; N-Methylscopolamine; Proline; Protein Conformation; Receptors, Muscarinic; Serine; Strychnine; Threonine; Valine

2006