Page last updated: 2024-08-25

n-methylscopolamine and scopolamine hydrobromide

n-methylscopolamine has been researched along with scopolamine hydrobromide in 120 studies

Research

Studies (120)

TimeframeStudies, this research(%)All Research%
pre-199053 (44.17)18.7374
1990's48 (40.00)18.2507
2000's13 (10.83)29.6817
2010's6 (5.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ball, WJ; Farr, CD; Norman, AB; Paula, S; Tabet, MR1
Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K1
Bermudez, M; Holzgrabe, U; Klöckner, J; Kostenis, E; Mohr, K; Schmitz, J; Schrage, R; Tränkle, C; van der Mey, D; Wolber, G1
Evenden, JL; Iversen, SD; Lavis, L1
Mazurkiewicz, M; Riekkinen, PJ; Sirviö, J1
Lydon, RG; Nakajima, S1
Banfi, S; Biagetti, R; Dorigotti, L; Magnani, M; Pozzi, O1
Lejeune, H; Soffié, M1
Duling, BR; Rivers, RJ1
Fenton, GW; Sloan, EP; Standage, KP1
Moran, PM1
Goto, Y; Hara, N; Hara, Y; Yamasaki, K1
Allen, Y; Arendt, T; Gray, JA; Hodges, H; Lantos, PL; Mitchell, SN; Sinden, J1
Vanderwolf, CH1
Church, AC; Flexner, JB; Flexner, LB1
Hootman, SR; Kovalcik, SA; Valles, SM1
Maeda, N; Matsuoka, N; Yamaguchi, I1
Chen, PS; Grau, JW; Illich, PA; Meagher, MW1
Brazier, MM; Dohanich, GP; McMullan, DM1
Janowsky, DS; Overstreet, DH; Rezvani, AH1
Feenstra, M; Stroet, J; van Haaren, F; van Hest, A1
Delen, FM; Ehlert, FJ1
Blanchard, DC; Blanchard, RJ; Rodgers, RJ; Wong, LK1
Gabriel, M; Henzi, V; Kubota, Y1
Endo, H; Goto, T; Ikari, H; Kuzuya, F; Tajima, T1
Garver, DL; Giordano, M; Hagenmeyer-Houser, SH; Russell, KH; Sanberg, PR; Zubrycki, EM1
Hunter, AJ; Murray, TK1
Hamburger-Bar, R; Lerer, B; Roth, D1
Hollingsworth, PJ; Smith, CB1
Cassel, JC; Kelche, C1
van Haaren, F; van Hest, A1
Fleckenstein, P; Müller, WE; Riemann, D; Stoll, L1
Berry, SD; Salvatierra, AT1
Shimizu, H; Watanabe, H1
van Haaren, F; van Hattum, T; van Hest, A1
Costa, LG1
Mayer, DJ; Watkins, LR1
Gillin, JC; Janowsky, D; Risch, SC; Ziegler, M1
Broks, P; Poppleton, P; Preston, GC; Stahl, SM; Traub, M; Ward, C1
Franklin, SR; Tang, AH1
Bogles, J; Petelka, S; Santi, A1
Fisher, SK1
Baron, SP; Peele, DB1
Dixon, CE; Hamm, RJ; Hayes, RL; Jenkins, LW; Lyeth, BG; Stonnington, HH; Young, HF1
Mueller, K1
Hamm, RJ; Knisely, JS1
Chen, YM; Cintrón, NM1
Mattingly, BA1
Bolhuis, JJ; Bures, J; Buresová, O1
Bodnar, RJ; Kramer, E; Sperber, ES1
Ladowsky, RL; Ossenkopp, KP; Sutherland, C1
Heise, GA; Viscardi, AP1
Barlow, RB; Dawson, S1
Corcoran, ME; Westerberg, V1
Heise, GA; Hudson, JD1
Ellis, J; Lenox, RH1
Berkowitz, A; Janowsky, DS; Risch, SC; Turken, A1
Furukawa, T; Imaizumi, J; Mizuki, Y; Noda, Y; Ushijima, I; Yamada, K; Yamada, M1
Parker, LA; Smith, RJ1
Bieger, D1
Raskin, LA; Rauch, SL1
Warburton, DM; Wesnes, K2
Driscoll, P; Gentsch, C; Martin, JR1
Hayes, RL; Katayama, Y; Kinscheck, IB; Mayer, DJ; Watkins, LR1
Horsburgh, RJ; Hughes, RN1
Blozovski, D; Hennocq, N1
Nagy, ZM; Porada, KJ1
Cool-Hauser, VA; Gormezano, I; Harvey, JA1
Ogawa, N; Yoshimura, H1
Hirshkowitz, M; Karacan, I; Thornby, JI1
Hughes, RA1
Glick, SD; Guido, RA1
Yoshimura, H1
Heale, VR; Vanderwolf, CH2
Herremans, AH; Hijzen, TH; Olivier, B; Slangen, JL1
Bohenek, DL; Fanselow, MS; Young, SL1
Chowdhury, P; Doi, R; Inoue, K; Kaji, H; Rayford, PL1
Higgins, GA; Jones, DN; Kirkby, DL1
Barnes, JC; Dennes, RP1
Petrillo, M; Powers, AS; Ritter, CA1
Freedman, SB; Patel, S1
Durkin, TP; Toumane, A1
Koch, KL; Stern, RM; Uijtdehaage, SH1
Moerschbaecher, JM; Pakarinen, ED1
Jones, SB; King, LB1
Bhatnagar, S; Costall, B; Murphy, D; Smythe, JW; Timothy, C1
Bjorklund, A; Dunnett, SB; Leanza, G; Muir, J; Nilsson, OG; Wiley, RG1
Dringenberg, HC; Vanderwolf, CH1
Bymaster, FP; Mitch, CH; Olesen, PH; Sauerberg, P; Shannon, HE; Sheardown, MJ; Suzdak, PD; Swedberg, MD; Ward, JS1
Dodart, JC; Mathis, C; Ungerer, A1
Vanderwolf, CH; Zibrowski, EM1
Deacon, RM; Nichols, BP; Rawlins, JN; Richmond, MA1
Barbanoj, M; Casas, M; Jané, F; Kulisevsky, J; Prat, G; Robledo, P1
Asaka, Y; Berry, SD; Seager, MA1
Davies, W; Humby, T; Laird, FM; Wilkinson, LS1
Anagnostaras, SG; Fanselow, MS; Goodrich, S; Maren, S; Sage, JR1
Chang, DJ; Cho, NJ; Hwang, JM; Kaang, BK; Kim, US; Lee, YS; Park, YS1
Gordon, CJ; Grantham, TA1
De Rosa, E; Hasselmo, ME1
Calignano, A; Di Pierro, P; Esposito, C; Mancuso, F; Porta, R; Sommella, MG1
Cook, JM; DeLorey, TM; He, X; Lameh, J; Lin, RC; Loew, GH; McBrady, B1
Cella, SG; Locatelli, V; Muller, EE; Pitsikas, N; Rigamonti, AE; Sala, M1
Janowsky, DS1
de Azevedo, LC; Häckl, LP; Marino-Neto, J; Paschoalini, MA; Zizemer, JR1
LAURSEN, EE1
HERXHEIMER, A1
NEZAMIS, JE; ROBERT, A1
HEIKEL, PE1
Eberle, EL; Shannon, HE1
Ballard, T; Feldon, J; Higgins, GA; Pryce, CR; Spinelli, S1
Shannon, HE; Yang, L1
Hodges, DB; Hogan, JB; Jones, KM; Lindner, MD; Markus, EJ1
Gattuso, B; Hogue, P; Lissek, S; Lynch, C; Nayal, C; Powers, AS1
Bitanihirwe, BK; Dubroqua, S; Feldon, J; Singer, P; Yee, BK1
Brown, KL; Comalli, DM; Kennard, JA; Sherer, DJ; Woodruff-Pak, DS1
Singer, P; Yee, BK1
Krochmal, AR; Roth, TC1

Reviews

1 review(s) available for n-methylscopolamine and scopolamine hydrobromide

ArticleYear
Multiple endogenous opiate and non-opiate analgesia systems: evidence of their existence and clinical implications.
    Annals of the New York Academy of Sciences, 1986, Volume: 467

    Topics: Acupuncture Therapy; Analgesia; Animals; Cholecystokinin; Conditioning, Classical; Desipramine; Dimethyl Sulfoxide; Drug Interactions; Electroshock; Endorphins; Enkephalin, Leucine; Mecamylamine; Morphine; N-Methylscopolamine; Naloxone; Naltrexone; Norepinephrine; Proglumide; Rats; Receptors, Cell Surface; Receptors, Cholecystokinin; Scopolamine; Scopolamine Derivatives; Serotonin; Spinal Cord

1986

Trials

4 trial(s) available for n-methylscopolamine and scopolamine hydrobromide

ArticleYear
Modelling dementia: effects of scopolamine on memory and attention.
    Neuropsychologia, 1988, Volume: 26, Issue:5

    Topics: Adolescent; Adult; Attention; Brain; Dementia; Female; Humans; Male; Memory; Mental Recall; Middle Aged; Models, Biological; N-Methylscopolamine; Neuropsychological Tests; Orientation; Reaction Time; Receptors, Cholinergic; Scopolamine; Scopolamine Derivatives

1988
Effects of scopolamine and nicotine on human rapid information processing performance.
    Psychopharmacology, 1984, Volume: 82, Issue:3

    Topics: Afferent Pathways; Cholinergic Fibers; Female; Humans; Male; N-Methylscopolamine; Nicotine; Psychomotor Performance; Scopolamine; Scopolamine Derivatives

1984
Effects of scopolamine on stimulus sensitivity and response bias in a visual vigilance task.
    Neuropsychobiology, 1983, Volume: 9, Issue:2-3

    Topics: Adolescent; Adult; Brain; Cholinergic Fibers; Depression, Chemical; Dose-Response Relationship, Drug; Female; Humans; Male; N-Methylscopolamine; Psychomotor Performance; Scopolamine; Scopolamine Derivatives

1983
Effects of scopolamine on autonomic profiles underlying motion sickness susceptibility.
    Aviation, space, and environmental medicine, 1993, Volume: 64, Issue:1

    Topics: Adult; Analysis of Variance; Drug Evaluation; Electric Stimulation; Electrocardiography; Fourier Analysis; Heart Rate; Humans; Male; Motion Sickness; N-Methylscopolamine; Parasympathetic Nervous System; Parasympatholytics; Rotation; Scopolamine; Scopolamine Derivatives; Vagus Nerve

1993

Other Studies

115 other study(ies) available for n-methylscopolamine and scopolamine hydrobromide

ArticleYear
Three-dimensional quantitative structure-activity relationship modeling of cocaine binding by a novel human monoclonal antibody.
    Journal of medicinal chemistry, 2004, Jan-01, Volume: 47, Issue:1

    Topics: Animals; Antibodies, Monoclonal; Binding, Competitive; Cocaine; Enzyme-Linked Immunosorbent Assay; Humans; Mice; Models, Molecular; Quantitative Structure-Activity Relationship; Radioligand Assay

2004
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.
    Bioorganic & medicinal chemistry, 2009, Oct-01, Volume: 17, Issue:19

    Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship

2009
QSAR-based permeability model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8

    Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2011
Dualsteric muscarinic antagonists--orthosteric binding pose controls allosteric subtype selectivity.
    Journal of medicinal chemistry, 2014, Aug-14, Volume: 57, Issue:15

    Topics: Allosteric Regulation; Animals; Atropine Derivatives; Binding Sites; CHO Cells; Cricetulus; Drug Inverse Agonism; Humans; Molecular Conformation; Molecular Docking Simulation; Molecular Dynamics Simulation; Muscarinic Agonists; Muscarinic Antagonists; Mutation; Naphthalimides; Phthalimides; Radioligand Assay; Receptor, Muscarinic M2; Scopolamine Derivatives; Stereoisomerism; Structure-Activity Relationship

2014
Blockade of conditioned taste aversion by scopolamine and N-methyl scopolamine: associative conditioning, not amnesia.
    Psychopharmacology, 1992, Volume: 106, Issue:2

    Topics: Amnesia; Animals; Ascorbic Acid; Avoidance Learning; Chlorides; Conditioning, Operant; Lithium; Lithium Chloride; Male; N-Methylscopolamine; Neostigmine; Parasympatholytics; Physostigmine; Rats; Rats, Inbred Strains; Scopolamine; Scopolamine Derivatives; Sucrose; Taste

1992
Effects of an inhibitor of GABA-aminotransferase (gamma-vinyl-GABA) on the spatial navigation deficit induced by muscarinic blockade.
    Pharmacology, biochemistry, and behavior, 1992, Volume: 43, Issue:1

    Topics: 4-Aminobutyrate Transaminase; Aminocaproates; Animals; Learning; Male; N-Methylscopolamine; Parasympatholytics; Rats; Rats, Wistar; Scopolamine; Scopolamine Derivatives; Space Perception; Swimming; Vigabatrin

1992
Differential effects of scopolamine on working and reference memory depend upon level of training.
    Pharmacology, biochemistry, and behavior, 1992, Volume: 43, Issue:2

    Topics: Animals; Male; Memory; Memory, Short-Term; N-Methylscopolamine; Parasympathetic Nervous System; Parasympatholytics; Rats; Scopolamine; Scopolamine Derivatives

1992
Oxiracetam antagonizes the disruptive effects of scopolamine on memory in the radial maze.
    Psychopharmacology, 1992, Volume: 106, Issue:2

    Topics: Animals; Dose-Response Relationship, Drug; Male; Memory; Motor Activity; N-Methylscopolamine; Parasympathetic Nervous System; Parasympatholytics; Physostigmine; Psychotropic Drugs; Pyrrolidines; Rats; Rats, Inbred Strains; Scopolamine; Scopolamine Derivatives

1992
Cholinergic blockade and response timing in rats.
    Psychopharmacology, 1992, Volume: 106, Issue:2

    Topics: Animals; Behavior, Animal; Conditioning, Operant; Male; Motivation; N-Methylscopolamine; Parasympatholytics; Physostigmine; Rats; Rats, Inbred Strains; Reinforcement Schedule; Scopolamine; Scopolamine Derivatives; Taste

1992
Arteriolar endothelial cell barrier separates two populations of muscarinic receptors.
    The American journal of physiology, 1992, Volume: 262, Issue:4 Pt 2

    Topics: Administration, Topical; Animals; Arterioles; Cricetinae; Endothelium, Vascular; Male; Mesocricetus; Methacholine Chloride; N-Methylscopolamine; Receptors, Muscarinic; Reference Values; Scopolamine; Scopolamine Derivatives

1992
Anticholinergic drug effects on quantitative electroencephalogram, visual evoked potential, and verbal memory.
    Biological psychiatry, 1992, Mar-15, Volume: 31, Issue:6

    Topics: Adult; Cerebral Cortex; Electroencephalography; Evoked Potentials, Visual; Female; Humans; Injections, Subcutaneous; Male; Memory, Short-Term; Mental Recall; N-Methylscopolamine; Parasympatholytics; Reaction Time; Retention, Psychology; Scopolamine; Scopolamine Derivatives; Verbal Learning

1992
Scopolamine deficits in negative patterning discrimination: evidence for a role of the central cholinergic system in retention but not acquisition of non-spatial configural association learning.
    Behavioural brain research, 1992, Jun-08, Volume: 48, Issue:2

    Topics: Amphetamine; Animals; Association Learning; Attention; Auditory Perception; Discrimination Learning; Hippocampus; Injections, Subcutaneous; Male; N-Methylscopolamine; Parasympatholytics; Problem Solving; Rats; Receptors, Cholinergic; Retention, Psychology; Scopolamine; Scopolamine Derivatives; Visual Perception

1992
GABAA and GABAB-receptor agonists evoked vagal nerve efferent transmission in the rat.
    Japanese journal of pharmacology, 1991, Volume: 55, Issue:1

    Topics: Acetylcholine; Animals; Baclofen; Bicuculline; Efferent Pathways; Gastric Acid; Male; Muscimol; N-Methylscopolamine; Parasympatholytics; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, GABA-A; Scopolamine; Scopolamine Derivatives; Synaptic Transmission; Vagus Nerve

1991
The effects of cholinergic drugs and cholinergic-rich foetal neural transplants on alcohol-induced deficits in radial maze performance in rats.
    Behavioural brain research, 1991, Apr-18, Volume: 43, Issue:1

    Topics: Acetylcholine; Alcohol Drinking; Alcoholism; Animals; Brain Mapping; Brain Tissue Transplantation; Cholinergic Fibers; Discrimination Learning; Ethanol; Fetal Tissue Transplantation; Ganglionic Blockers; Hexamethonium; Hexamethonium Compounds; Male; Mecamylamine; Mental Recall; Mesencephalon; N-Methylscopolamine; Nerve Regeneration; Nicotine; Norepinephrine; Orientation; Parasympatholytics; Rats; Rats, Inbred Strains; Receptors, Cholinergic; Retention, Psychology; Scopolamine; Scopolamine Derivatives

1991
Anti-muscarinic drug effects in a swim-to-platform test: dose-response relations.
    Behavioural brain research, 1991, Aug-29, Volume: 44, Issue:2

    Topics: Animals; Atropine; Behavior, Animal; Dose-Response Relationship, Drug; Injections, Intraperitoneal; Injections, Subcutaneous; Male; N-Methylscopolamine; Parasympatholytics; Rats; Scopolamine; Scopolamine Derivatives; Swimming

1991
Long-term suppression in mice of the development of complementary memory storage sites: effect of a muscarinic antagonist.
    Pharmacology, biochemistry, and behavior, 1991, Volume: 39, Issue:3

    Topics: Amnesia; Animals; Brain; Injections; Injections, Intraventricular; Injections, Subcutaneous; Memory; Mice; N-Methylscopolamine; Parasympatholytics; Parasympathomimetics; Puromycin; Scopolamine; Scopolamine Derivatives

1991
Mechanism of agonist-induced downregulation of muscarinic receptors in rat pancreatic acini.
    The American journal of physiology, 1991, Volume: 261, Issue:1 Pt 1

    Topics: Animals; Binding Sites; Carbachol; Cells, Cultured; Down-Regulation; Kinetics; N-Methylscopolamine; Pancreas; Parasympatholytics; Rats; Receptors, Muscarinic; Scopolamine; Scopolamine Derivatives

1991
Septohippocampal cholinergic pathway and penile erections induced by dopaminergic and cholinergic stimulants.
    Brain research, 1990, Dec-24, Volume: 537, Issue:1-2

    Topics: Amantadine; Animals; Apomorphine; Brain; Denervation; Dopamine Agents; Dose-Response Relationship, Drug; Hippocampus; Male; N-Methylscopolamine; Neural Pathways; Parasympathetic Nervous System; Parasympathomimetics; Penile Erection; Pilocarpine; Rats; Scopolamine; Scopolamine Derivatives; Sulpiride

1990
Role of cholinergic systems in pain modulation: I. Impact of scopolamine on environmentally induced hypoalgesia and pain reactivity.
    Behavioral neuroscience, 1991, Volume: 105, Issue:1

    Topics: Animals; Arousal; Electroshock; Habituation, Psychophysiologic; Male; Mental Recall; N-Methylscopolamine; Nociceptors; Parasympatholytics; Rats; Rats, Inbred Strains; Reaction Time; Receptors, Cholinergic; Scopolamine; Scopolamine Derivatives; Sensory Thresholds; Social Environment; Vocalization, Animal

1991
Cholinergic regulation of sexual behavior in female hamsters.
    Physiology & behavior, 1990, Volume: 47, Issue:1

    Topics: Animals; Brain; Cerebral Ventricles; Cholinergic Antagonists; Cricetinae; Estradiol; Female; Injections, Intraperitoneal; Mesocricetus; N-Methylscopolamine; Ovariectomy; Physostigmine; Posture; Progesterone; Scopolamine; Scopolamine Derivatives; Sexual Behavior, Animal; Time Factors

1990
Reduction in ethanol preference following injection of centrally and peripherally acting antimuscarinic agents.
    Alcohol and alcoholism (Oxford, Oxfordshire), 1990, Volume: 25, Issue:1

    Topics: Alcohol Drinking; Animals; Brain; Dose-Response Relationship, Drug; N-Methylscopolamine; Parasympatholytics; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Scopolamine; Scopolamine Derivatives

1990
Scopolamine differentially disrupts the behavior of male and female Wistar rats in a delayed nonmatching to position procedure.
    Pharmacology, biochemistry, and behavior, 1990, Volume: 35, Issue:4

    Topics: Animals; Dose-Response Relationship, Drug; Female; Male; Memory; N-Methylscopolamine; Parasympatholytics; Random Allocation; Rats; Rats, Inbred Strains; Scopolamine; Scopolamine Derivatives; Sex Characteristics

1990
Influence of pH on the binding of scopolamine and N-methylscopolamine to muscarinic receptors in the corpus striatum and heart of rats.
    Molecular pharmacology, 1990, Volume: 38, Issue:1

    Topics: Animals; Corpus Striatum; Hydrogen-Ion Concentration; In Vitro Techniques; Myocardium; N-Methylscopolamine; Rats; Receptors, Muscarinic; Scopolamine; Scopolamine Derivatives

1990
Effects of scopolamine on antipredator defense reactions in wild and laboratory rats.
    Pharmacology, biochemistry, and behavior, 1990, Volume: 36, Issue:3

    Topics: Aggression; Animals; Cats; Defense Mechanisms; Fear; Female; Male; Muridae; N-Methylscopolamine; Parasympatholytics; Rats; Scopolamine; Scopolamine Derivatives; Species Specificity

1990
Scopolamine but not haloperidol disrupts training-induced neuronal activity in cingulate cortex and limbic thalamus during learning in rabbits.
    Brain research, 1990, Jun-04, Volume: 518, Issue:1-2

    Topics: Animals; Avoidance Learning; Dose-Response Relationship, Drug; Electroshock; Gyrus Cinguli; Haloperidol; Limbic System; Male; N-Methylscopolamine; Neurons; Parasympatholytics; Rabbits; Reference Values; Scopolamine; Scopolamine Derivatives; Thalamus

1990
Some effects of CNS cholinergic neurons on memory.
    Journal of neural transmission. Supplementum, 1990, Volume: 30

    Topics: Acetylcholine; Animals; Avoidance Learning; Brain; Chromatography, High Pressure Liquid; Male; Memory; N-Methylscopolamine; Neurons; Parasympathetic Nervous System; Parasympatholytics; Rats; Rats, Inbred Strains; Scopolamine; Scopolamine Derivatives

1990
Neuroleptic-induced emotional defecation: effects of scopolamine and haloperidol.
    Psychopharmacology, 1989, Volume: 99, Issue:1

    Topics: Animals; Defecation; Emotions; Haloperidol; Male; N-Methylscopolamine; Parasympathetic Nervous System; Rats; Rats, Inbred Strains; Scopolamine; Scopolamine Derivatives

1989
Cholinergic mechanisms in a simple test of olfactory learning in the rat.
    Psychopharmacology, 1989, Volume: 99, Issue:2

    Topics: Animals; Brain; Discrimination, Psychological; Injections, Intraventricular; Learning; Male; N-Methylscopolamine; Parasympathetic Nervous System; Rats; Scopolamine; Scopolamine Derivatives; Smell

1989
Peripheral versus central manifestations in the toxic interaction of lithium and pilocarpine.
    Biological psychiatry, 1989, Jan-15, Volume: 25, Issue:2

    Topics: Animals; Brain; Chlorides; Cholinergic Fibers; Dose-Response Relationship, Drug; Drug Synergism; Lithium; Lithium Chloride; Male; N-Methylscopolamine; Peripheral Nerves; Pilocarpine; Rats; Rats, Inbred Strains; Scopolamine; Scopolamine Derivatives

1989
Effects of muscarinic receptor agonists and antagonists on alpha 2-adrenoceptors in rat brain.
    European journal of pharmacology, 1989, Sep-13, Volume: 168, Issue:2

    Topics: Animals; Atropine; Atropine Derivatives; Brain; Clonidine; Male; N-Methylscopolamine; Neurons; Oxotremorine; Parasympatholytics; Pilocarpine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Muscarinic; Scopolamine; Scopolamine Derivatives; Time Factors

1989
Scopolamine treatment and fimbria-fornix lesions: mimetic effects on radial maze performance.
    Physiology & behavior, 1989, Volume: 46, Issue:3

    Topics: Animals; Behavior, Animal; Female; Limbic System; Memory; N-Methylscopolamine; Physostigmine; Rats; Scopolamine; Scopolamine Derivatives

1989
The effects of scopolamine and methylscopolamine on visual and auditory discriminations in male and female Wistar rats.
    Pharmacology, biochemistry, and behavior, 1989, Volume: 32, Issue:3

    Topics: Acoustic Stimulation; Animals; Auditory Pathways; Female; Male; N-Methylscopolamine; Photic Stimulation; Rats; Rats, Inbred Strains; Scopolamine; Scopolamine Derivatives; Visual Pathways

1989
A simple but highly sensitive radioreceptor assay for the determination of scopolamine and biperiden in human plasma.
    Research communications in chemical pathology and pharmacology, 1989, Volume: 64, Issue:1

    Topics: Animals; Biperiden; Brain Chemistry; Humans; Male; Mice; N-Methylscopolamine; Piperidines; Radioligand Assay; Scopolamine; Scopolamine Derivatives

1989
Scopolamine disruption of septo-hippocampal activity and classical conditioning.
    Behavioral neuroscience, 1989, Volume: 103, Issue:4

    Topics: Animals; Conditioning, Eyelid; Electroencephalography; Evoked Potentials; Female; Hippocampus; Male; N-Methylscopolamine; Parasympatholytics; Rabbits; Receptors, Cholinergic; Scopolamine; Scopolamine Derivatives; Septum Pellucidum

1989
Effect of anticholinergic drugs on striatal acetylcholine release and motor activity in freely moving rats studied by brain microdialysis.
    Japanese journal of pharmacology, 1989, Volume: 51, Issue:1

    Topics: Acetylcholine; Animals; Atropine; Brain Chemistry; Corpus Striatum; Dialysis; Male; Motor Activity; N-Methylscopolamine; Parasympatholytics; Rats; Rats, Inbred Strains; Scopolamine; Scopolamine Derivatives; Tissue Distribution

1989
Scopolamine and methylscopolamine differentially affect fixed-consecutive-number performance of male and female Wistar rats.
    Pharmacology, biochemistry, and behavior, 1989, Volume: 33, Issue:2

    Topics: Animals; Behavior, Animal; Discrimination, Psychological; Female; Male; N-Methylscopolamine; Parasympatholytics; Rats; Rats, Inbred Strains; Reinforcement Schedule; Scopolamine; Scopolamine Derivatives; Sex Factors

1989
Specific binding of [3H]methylscopolamine to glass fibre filters.
    The Journal of pharmacy and pharmacology, 1987, Volume: 39, Issue:3

    Topics: Animals; Aplysia; Atropine; Atropine Derivatives; Chemical Phenomena; Chemistry, Physical; Filtration; gamma-Aminobutyric Acid; Glass; N-Methylscopolamine; Norepinephrine; Receptors, Muscarinic; Scopolamine; Scopolamine Derivatives

1987
Antagonistic effects of scopolamine and atropine on the physostigmine response in man.
    Military medicine, 1987, Volume: 152, Issue:11

    Topics: Adult; Affect; Atropine; Cardiovascular System; Double-Blind Method; Drug Evaluation; Humans; Male; N-Methylscopolamine; Neurosecretory Systems; Parasympatholytics; Physostigmine; Scopolamine; Scopolamine Derivatives

1987
Discriminative stimulus properties of physostigmine in rats.
    European journal of pharmacology, 1988, Aug-09, Volume: 153, Issue:1

    Topics: Animals; Conditioning, Operant; Discrimination, Psychological; Dose-Response Relationship, Drug; Male; N-Methylscopolamine; Physostigmine; Pirenzepine; Rats; Rats, Inbred Strains; Receptors, Cholinergic; Reinforcement Schedule; Scopolamine; Scopolamine Derivatives

1988
The effect of scopolamine and physostigmine on working and reference memory in pigeons.
    Behavioral and neural biology, 1988, Volume: 49, Issue:1

    Topics: Animals; Columbidae; Memory; Memory, Short-Term; N-Methylscopolamine; Physostigmine; Receptors, Cholinergic; Scopolamine; Scopolamine Derivatives; Time Factors

1988
Recognition of muscarinic cholinergic receptors in human SK-N-SH neuroblastoma cells by quaternary and tertiary ligands is dependent upon temperature, cell integrity, and the presence of agonists.
    Molecular pharmacology, 1988, Volume: 33, Issue:4

    Topics: Atropine; Binding, Competitive; Carbachol; Humans; Kinetics; Ligands; N-Methylscopolamine; Neuroblastoma; Quinuclidinyl Benzilate; Receptors, Muscarinic; Scopolamine; Scopolamine Derivatives; Temperature; Tumor Cells, Cultured

1988
Effects of scopolamine on repeated acquisition of radial-arm maze performance by rats.
    Journal of the experimental analysis of behavior, 1988, Volume: 49, Issue:2

    Topics: Animals; Discrimination Learning; Dose-Response Relationship, Drug; Male; N-Methylscopolamine; Orientation; Rats; Rats, Inbred Strains; Scopolamine; Scopolamine Derivatives

1988
Effects of anticholinergic treatment on transient behavioral suppression and physiological responses following concussive brain injury to the rat.
    Brain research, 1988, May-10, Volume: 448, Issue:1

    Topics: Animals; Blood Pressure; Brain; Brain Concussion; Heart Rate; Male; Mecamylamine; N-Methylscopolamine; Parasympatholytics; Rats; Rats, Inbred Strains; Reflex; Scopolamine; Scopolamine Derivatives

1988
Voltammetric evidence in vivo of cholinergic modulation of extracellular ascorbic acid and uric acid in rat striatum.
    Brain research, 1987, Apr-07, Volume: 408, Issue:1-2

    Topics: Animals; Ascorbic Acid; Cholinergic Fibers; Corpus Striatum; Electrochemistry; Male; N-Methylscopolamine; Pilocarpine; Rats; Rats, Inbred Strains; Scopolamine; Scopolamine Derivatives; Uric Acid

1987
Developmental differences in the analgesia produced by the central cholinergic system.
    Developmental psychobiology, 1987, Volume: 20, Issue:3

    Topics: Age Factors; Animals; Male; N-Methylscopolamine; Oxotremorine; Pain; Rats; Rats, Inbred Strains; Reaction Time; Receptors, Muscarinic; Scopolamine; Scopolamine Derivatives; Sensory Thresholds

1987
A sensitive radioreceptor assay for determining scopolamine concentrations in plasma and urine.
    Journal of pharmaceutical sciences, 1987, Volume: 76, Issue:4

    Topics: Chromatography, Liquid; Humans; N-Methylscopolamine; Radioligand Assay; Receptors, Muscarinic; Scopolamine; Scopolamine Derivatives

1987
Scopolamine disrupts leverpress shock escape learning in rats.
    Pharmacology, biochemistry, and behavior, 1986, Volume: 24, Issue:6

    Topics: Analysis of Variance; Animals; Avoidance Learning; Conditioning, Operant; Escape Reaction; Male; N-Methylscopolamine; Parasympathetic Nervous System; Rats; Rats, Inbred Strains; Scopolamine; Scopolamine Derivatives; Septum Pellucidum

1986
Differential effects of cholinergic blockade on performance of rats in the water tank navigation task and in a radial water maze.
    Behavioral neuroscience, 1986, Volume: 100, Issue:4

    Topics: Animals; Discrimination Learning; Hippocampus; Male; Memory; Mental Recall; N-Methylscopolamine; Neural Pathways; Orientation; Rats; Receptors, Cholinergic; Retention, Psychology; Scopolamine; Scopolamine Derivatives

1986
Effects of muscarinic receptor antagonism upon two forms of stress-induced analgesia.
    Pharmacology, biochemistry, and behavior, 1986, Volume: 25, Issue:1

    Topics: Acetylcholine; Animals; Body Temperature; Feeding Behavior; Male; N-Methylscopolamine; Pain; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Scopolamine; Scopolamine Derivatives; Sensory Thresholds; Stress, Physiological

1986
Motor activity changes and conditioned taste aversions induced by administration of scopolamine in rats: role of the area postrema.
    Pharmacology, biochemistry, and behavior, 1986, Volume: 25, Issue:1

    Topics: Animals; Avoidance Learning; Food Preferences; Male; Motor Activity; N-Methylscopolamine; Neurosecretory Systems; Rats; Scopolamine; Scopolamine Derivatives; Taste

1986
Effects of scopolamine on components of delayed response performance in the rat.
    Pharmacology, biochemistry, and behavior, 1986, Volume: 25, Issue:3

    Topics: Animals; Discrimination, Psychological; Dose-Response Relationship, Drug; Male; Memory; N-Methylscopolamine; Rats; Rats, Inbred Strains; Reinforcement, Psychology; Retention, Psychology; Scopolamine; Scopolamine Derivatives

1986
The selectivity of the (-)-and (+)-forms of hyoscine methiodide and of hyoscyamine camphorsulphonate for muscarinic (M2) receptors.
    British journal of pharmacology, 1986, Volume: 89, Issue:2

    Topics: Animals; Atropine; Guinea Pigs; Heart; Ileum; In Vitro Techniques; Muscle, Smooth; Myocardial Contraction; N-Methylscopolamine; Receptors, Muscarinic; Scopolamine; Scopolamine Derivatives; Stereoisomerism

1986
Antagonism of central but not peripheral cholinergic receptors retards amygdala kindling in rats.
    Experimental neurology, 1987, Volume: 95, Issue:1

    Topics: Amygdala; Animals; Anticonvulsants; Brain; Kindling, Neurologic; Male; Membrane Potentials; N-Methylscopolamine; Rats; Rats, Inbred Strains; Receptors, Cholinergic; Scopolamine; Scopolamine Derivatives

1987
Effects of pesticides and drugs on working memory in rats: continuous delayed response.
    Pharmacology, biochemistry, and behavior, 1985, Volume: 23, Issue:4

    Topics: Animals; Carbaryl; Chlordiazepoxide; Chlorphenamidine; Conditioning, Operant; Discrimination, Psychological; Male; Memory; N-Methylscopolamine; Nitriles; Pesticides; Physostigmine; Propoxur; Pyrethrins; Rats; Rats, Inbred Strains; Scopolamine; Scopolamine Derivatives

1985
Quaternary forms of classical muscarinic antagonists distinguish subpopulations of muscarinic receptors: correlation with gallamine-defined subpopulations.
    Biochemical and biophysical research communications, 1985, Feb-15, Volume: 126, Issue:3

    Topics: Allosteric Site; Animals; Atropine; Atropine Derivatives; Binding, Competitive; Brain; Gallamine Triethiodide; In Vitro Techniques; Male; N-Methylscopolamine; Parasympatholytics; Quinuclidinyl Benzilate; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Scopolamine; Scopolamine Derivatives

1985
Antagonism of physostigmine induced lethality by a combination of scopolamine and methscopolamine.
    Acta pharmacologica et toxicologica, 1985, Volume: 56, Issue:2

    Topics: Animals; Drug Synergism; Mice; N-Methylscopolamine; Physostigmine; Scopolamine; Scopolamine Derivatives

1985
Characteristics of yawning behavior induced by apomorphine, physostigmine and pilocarpine.
    Archives internationales de pharmacodynamie et de therapie, 1985, Volume: 273, Issue:2

    Topics: Animals; Apomorphine; Behavior, Animal; Haloperidol; Male; Mecamylamine; N-Methylscopolamine; Physostigmine; Pilocarpine; Rats; Rats, Inbred Strains; Scopolamine; Scopolamine Derivatives; Time Factors

1985
Chin rub CRs are elicited by flavors associated with apomorphine, scopolamine, methscopolamine, physostigmine and neostigmine.
    Pharmacology, biochemistry, and behavior, 1985, Volume: 23, Issue:4

    Topics: Animals; Apomorphine; Conditioning, Operant; Male; N-Methylscopolamine; Neostigmine; Physostigmine; Rats; Rats, Inbred Strains; Scopolamine; Scopolamine Derivatives; Taste

1985
Muscarinic activation of rhombencephalic neurones controlling oesophageal peristalsis in the rat.
    Neuropharmacology, 1984, Volume: 23, Issue:12A

    Topics: Acetylcholine; Animals; Deglutition; Electric Stimulation; Esophagus; Motor Neurons; N-Methylscopolamine; Neurons; Parasympatholytics; Peristalsis; Physostigmine; Quipazine; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Scopolamine; Scopolamine Derivatives; Synaptic Transmission

1984
Cholinergic mediation of spatial memory in the preweanling rat: application of the radial arm maze paradigm.
    Behavioral neuroscience, 1984, Volume: 98, Issue:1

    Topics: Animals; Animals, Newborn; Arecoline; Cholinergic Fibers; Discrimination Learning; Female; Hippocampus; Male; Memory; Mental Recall; N-Methylscopolamine; Orientation; Rats; Rats, Inbred Strains; Retention, Psychology; Scopolamine; Scopolamine Derivatives; Synaptic Transmission

1984
Differential response to cholinergic stimulation in psychogenitically selected rat lines.
    Psychopharmacology, 1984, Volume: 83, Issue:3

    Topics: Animals; Body Temperature; Female; Male; N-Methylscopolamine; Oxotremorine; Parasympathetic Nervous System; Rats; Rats, Inbred Strains; Salivation; Scopolamine; Scopolamine Derivatives; Tears; Tremor

1984
Muscarinic cholinergic mediation of opiate and non-opiate environmentally induced analgesias.
    Brain research, 1984, May-23, Volume: 300, Issue:2

    Topics: Analgesia; Animals; Central Nervous System; Cholinergic Fibers; Conditioning, Classical; Electroshock; Male; Mecamylamine; N-Methylscopolamine; Pain; Rats; Receptors, Muscarinic; Scopolamine; Scopolamine Derivatives

1984
Modification of novelty preferences in rats by current and prior treatment with scopolamine and methylscopolamine.
    Psychopharmacology, 1981, Volume: 73, Issue:4

    Topics: Animals; Exploratory Behavior; Female; Male; Motor Activity; N-Methylscopolamine; Rats; Scopolamine; Scopolamine Derivatives; Sex Factors; Time Factors

1981
Effects of antimuscarinic cholinergic drugs injected systemically or into the hippocampo-entorhinal area upon passive avoidance learning in young rats.
    Psychopharmacology, 1982, Volume: 76, Issue:4

    Topics: Age Factors; Animals; Atropine; Atropine Derivatives; Avoidance Learning; Extinction, Psychological; Female; Hippocampus; Limbic System; Male; N-Methylscopolamine; Rats; Receptors, Muscarinic; Retention, Psychology; Scopolamine; Scopolamine Derivatives

1982
Delayed emergency of cholinergic inhibitory functioning in undernourished mice.
    Behavioral and neural biology, 1982, Volume: 35, Issue:3

    Topics: Animals; Arousal; Brain; Female; Male; Mice; Motor Activity; N-Methylscopolamine; Neural Inhibition; Protein-Energy Malnutrition; Receptors, Cholinergic; Scopolamine; Scopolamine Derivatives

1982
Effects of scopolamine and methylscopolamine on classical conditioning of the rabbit nictitating membrane response.
    The Journal of pharmacology and experimental therapeutics, 1983, Volume: 225, Issue:1

    Topics: Acoustic Stimulation; Animals; Conditioning, Classical; Conditioning, Eyelid; Dose-Response Relationship, Drug; Electric Stimulation; Female; Male; N-Methylscopolamine; Nictitating Membrane; Photic Stimulation; Rabbits; Scopolamine; Scopolamine Derivatives

1983
Pharmaco-ethological analysis of agonistic behavior between resident and intruder mice: effect of anticholinergic drugs.
    Japanese journal of pharmacology, 1982, Volume: 32, Issue:6

    Topics: Aggression; Animals; Humans; Male; Mice; Mice, Inbred ICR; Motor Activity; N-Methylscopolamine; Parasympatholytics; Rats; Scopolamine; Scopolamine Derivatives

1982
Sleep spindles: pharmacological effects in humans.
    Sleep, 1982, Volume: 5, Issue:1

    Topics: Atropine; Azepines; Caffeine; Cerebral Cortex; Computers; Dose-Response Relationship, Drug; Double-Blind Method; Electroencephalography; Evoked Potentials; Flurazepam; Haloperidol; Humans; N-Methylscopolamine; Phenobarbital; Scopolamine; Scopolamine Derivatives; Sleep Stages; Thalidomide; Tryptophan

1982
Anticholinergic drugs, blood-brain-barrier and tonic immobility in chickens.
    Physiology & behavior, 1982, Volume: 29, Issue:1

    Topics: Aging; Animals; Atropine; Atropine Derivatives; Blood-Brain Barrier; Chickens; Dose-Response Relationship, Drug; Fear; Motor Activity; N-Methylscopolamine; Parasympatholytics; Scopolamine; Scopolamine Derivatives

1982
Scopolamine self-administration: cholinergic involvement in reward mechanisms.
    Life sciences, 1982, Aug-30, Volume: 31, Issue:9

    Topics: Animals; Arecoline; Atropine; Behavior, Animal; Female; Mecamylamine; N-Methylscopolamine; Oxotremorine; Parasympathetic Nervous System; Physostigmine; Pilocarpine; Rats; Rats, Inbred Strains; Reinforcement, Psychology; Reward; Scopolamine; Scopolamine Derivatives; Self Administration

1982
Regional changes in brain cholinergic enzyme activities after bilateral olfactory bulbectomy in relation to mouse-killing behavior by rats.
    Pharmacology, biochemistry, and behavior, 1981, Volume: 15, Issue:3

    Topics: Acetylcholinesterase; Aggression; Animals; Brain; Choline O-Acetyltransferase; Humans; Male; N-Methylscopolamine; Olfactory Bulb; Rats; Rats, Inbred Strains; Scopolamine; Scopolamine Derivatives

1981
Scopolamine blocks olfaction-induced fast waves but not olfactory evoked potentials in the dentate gyrus.
    Behavioural brain research, 1995, Volume: 68, Issue:1

    Topics: Animals; Electric Stimulation; Electroencephalography; Evoked Potentials; Hippocampus; Male; N-Methylscopolamine; Olfactory Bulb; Parasympatholytics; Rats; Scopolamine; Scopolamine Derivatives; Smell; Stereotaxic Techniques

1995
Cholinergic drug effects on a delayed conditional discrimination task in the rat.
    Behavioral neuroscience, 1995, Volume: 109, Issue:3

    Topics: Animals; Appetitive Behavior; Arecoline; Brain; Conditioning, Operant; Discrimination Learning; Dose-Response Relationship, Drug; Injections, Intraperitoneal; Male; Mental Recall; N-Methylscopolamine; Oxotremorine; Parasympatholytics; Physostigmine; Rats; Rats, Wistar; Receptors, Cholinergic; Retention, Psychology; Scopolamine; Scopolamine Derivatives; Synaptic Transmission; Tacrine

1995
Scopolamine impairs acquisition and facilitates consolidation of fear conditioning: differential effects for tone vs context conditioning.
    Neurobiology of learning and memory, 1995, Volume: 63, Issue:2

    Topics: Acoustic Stimulation; Amygdala; Animals; Arousal; Association Learning; Brain; Cholinergic Fibers; Conditioning, Classical; Discrimination Learning; Dose-Response Relationship, Drug; Electroshock; Fear; Hippocampus; Long-Term Potentiation; Male; Mental Recall; N-Methylscopolamine; Parasympatholytics; Rats; Retention, Psychology; Scopolamine; Scopolamine Derivatives; Social Environment

1995
Structural and functional changes of exocrine pancreas induced by FK506 in rats.
    Gastroenterology, 1993, Volume: 104, Issue:4

    Topics: Amylases; Analysis of Variance; Animals; Atropine; Body Weight; Calcimycin; Calcium; Carbachol; Cholecystokinin; Colforsin; Cytosol; Dose-Response Relationship, Drug; Feeding Behavior; Kinetics; Male; N-Methylscopolamine; Pancreas; Rats; Rats, Sprague-Dawley; Receptors, Cholecystokinin; Reference Values; Scopolamine; Scopolamine Derivatives; Secretin; Sincalide; Tacrolimus; Tetradecanoylphorbol Acetate; Time Factors; Trypsinogen; Vasoactive Intestinal Peptide

1993
Influence of prefeeding and scopolamine upon performance in a delayed matching-to-position task.
    Behavioural brain research, 1995, Volume: 67, Issue:2

    Topics: Animals; Choice Behavior; Conditioning, Operant; Discrimination Learning; Dose-Response Relationship, Drug; Male; Memory, Short-Term; Mental Recall; Motivation; N-Methylscopolamine; Orientation; Parasympatholytics; Rats; Reaction Time; Satiation; Scopolamine; Scopolamine Derivatives

1995
Attenuation of scopolamine-induced spatial memory deficits in the rat by cholinomimetic and non-cholinomimetic drugs using a novel task in the 12-arm radial maze.
    Psychopharmacology, 1993, Volume: 111, Issue:4

    Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Biphenyl Compounds; Bridged Bicyclo Compounds; Cholinergic Agents; Dose-Response Relationship, Drug; Imidazoles; Injections, Intraventricular; Losartan; Male; Maze Learning; Memory; Memory, Short-Term; N-Methylscopolamine; Parasympatholytics; Physostigmine; Pilocarpine; Rats; Scopolamine; Scopolamine Derivatives; Space Perception; Spiro Compounds; Tetrazoles

1993
Dentate gyrus and olfactory bulb responses to olfactory and noxious stimulation in urethane anaesthetized rats.
    Brain research, 1994, Aug-01, Volume: 652, Issue:2

    Topics: Anesthesia; Animals; Electrophysiology; Hippocampus; Male; Muscarinic Antagonists; N-Methylscopolamine; Olfactory Bulb; Pain; Parasympatholytics; Rats; Scopolamine; Scopolamine Derivatives; Smell; Urethane

1994
A role for acetylcholine in spatial memory in turtles.
    Physiology & behavior, 1994, Volume: 56, Issue:1

    Topics: Acetylcholine; Animals; Brain Mapping; Cerebral Cortex; Discrimination Learning; Mental Recall; N-Methylscopolamine; Neural Pathways; Orientation; Prosencephalon; Retention, Psychology; Scopolamine; Scopolamine Derivatives; Turtles

1994
The muscarinic receptor agonist L-658,903 modulates the in vivo accumulation of inositol monophosphates in mouse brain.
    European journal of pharmacology, 1994, May-17, Volume: 267, Issue:3

    Topics: Animals; Binding Sites; Brain; Dose-Response Relationship, Drug; In Vitro Techniques; Inositol Phosphates; Lithium Chloride; Male; Mice; N-Methylscopolamine; Oxadiazoles; Oxotremorine; Parasympatholytics; Pilocarpine; Quinuclidines; Receptors, Muscarinic; Scopolamine; Scopolamine Derivatives

1994
Time gradient for post-test vulnerability to scopolamine-induced amnesia following the initial acquisition session of a spatial reference memory task in mice.
    Behavioral and neural biology, 1993, Volume: 60, Issue:2

    Topics: Animals; Cerebral Cortex; Cholinergic Fibers; Discrimination Learning; Dose-Response Relationship, Drug; Hippocampus; Injections, Intraperitoneal; Male; Mental Recall; Mice; Mice, Inbred C57BL; N-Methylscopolamine; Neural Pathways; Orientation; Parasympatholytics; Scopolamine; Scopolamine Derivatives; Septal Nuclei; Substantia Innominata

1993
Comparison of the effects of scopolamine and methylscopolamine on the performance of a fixed-ratio discrimination in squirrel monkeys.
    Pharmacology, biochemistry, and behavior, 1993, Volume: 44, Issue:4

    Topics: Animals; Discrimination, Psychological; Dose-Response Relationship, Drug; Female; N-Methylscopolamine; Parasympatholytics; Reinforcement Schedule; Saimiri; Scopolamine; Scopolamine Derivatives

1993
Muscarinic cholinergic receptors in brain and atrial membranes of adult brook trout (Salvelinus fontinalis) measured by radioligand binding techniques.
    Comparative biochemistry and physiology. Part C, Pharmacology, toxicology & endocrinology, 1995, Volume: 112, Issue:1

    Topics: Animals; Atropine; Binding, Competitive; Brain Chemistry; Carbachol; Heart Atria; Kinetics; Muscarinic Agonists; Muscarinic Antagonists; N-Methylscopolamine; Oxotremorine; Parasympatholytics; Pirenzepine; Radioligand Assay; Receptors, Muscarinic; Scopolamine; Scopolamine Derivatives; Trout

1995
Muscarinic antagonists are anxiogenic in rats tested in the black-white box.
    Pharmacology, biochemistry, and behavior, 1996, Volume: 54, Issue:1

    Topics: Animals; Anxiety; Arousal; Behavior, Animal; Hypothalamo-Hypophyseal System; Male; Motor Activity; Muscarinic Antagonists; N-Methylscopolamine; Parasympatholytics; Pituitary-Adrenal System; Rats; Scopolamine; Scopolamine Derivatives; Stress, Psychological; Theta Rhythm

1996
Selective immunolesioning of the basal forebrain cholinergic system disrupts short-term memory in rats.
    The European journal of neuroscience, 1996, Volume: 8, Issue:7

    Topics: Animals; Antibodies, Monoclonal; Arecoline; Cholinergic Agents; Conditioning, Operant; Female; Hippocampus; Immunotoxins; Memory Disorders; Memory, Short-Term; N-Glycosyl Hydrolases; N-Methylscopolamine; Parasympatholytics; Prosencephalon; Rats; Rats, Sprague-Dawley; Reaction Time; Ribosome Inactivating Proteins, Type 1; Saporins; Scopolamine; Scopolamine Derivatives; Septum Pellucidum

1996
Cholinergic activation of the electrocorticogram: an amygdaloid activating system.
    Experimental brain research, 1996, Volume: 108, Issue:2

    Topics: Amygdala; Animals; Electric Stimulation; Electroencephalography; Excitatory Amino Acid Antagonists; Hippocampus; Male; Mesencephalon; Muscarinic Antagonists; N-Methylscopolamine; Parasympathetic Nervous System; Parasympatholytics; Physical Stimulation; Prosencephalon; Rats; Scopolamine; Scopolamine Derivatives; Serotonin

1996
M1 receptor agonist activity is not a requirement for muscarinic antinociception.
    The Journal of pharmacology and experimental therapeutics, 1997, Volume: 281, Issue:2

    Topics: Analgesics; Animals; Atrial Function; Cell Line; Cricetinae; Guinea Pigs; Heart Atria; Humans; Hydrolysis; In Vitro Techniques; Inositol Phosphates; Male; Mice; Muscarinic Agonists; Muscle Contraction; N-Methylscopolamine; Naltrexone; Rabbits; Rats; Rats, Wistar; Receptor, Muscarinic M1; Receptors, Muscarinic; Scopolamine; Scopolamine Derivatives; Transfection; Vas Deferens

1997
Scopolamine-induced deficits in a two-trial object recognition task in mice.
    Neuroreport, 1997, Mar-24, Volume: 8, Issue:5

    Topics: Analysis of Variance; Animals; Blood-Brain Barrier; Drug Evaluation, Preclinical; Male; Mice; Motor Activity; Muscarinic Antagonists; N-Methylscopolamine; Pattern Recognition, Visual; Scopolamine; Scopolamine Derivatives

1997
Oscillatory fast wave activity in the rat pyriform cortex: relations to olfaction and behavior.
    Brain research, 1997, Aug-22, Volume: 766, Issue:1-2

    Topics: Acoustic Stimulation; Anesthetics, Intravenous; Animals; Behavior, Animal; Electrophysiology; Hippocampus; Male; Muscarinic Antagonists; N-Methylscopolamine; Odorants; Olfactory Bulb; Olfactory Mucosa; Olfactory Pathways; Parasympatholytics; Periodicity; Rats; Rats, Inbred Strains; Scopolamine; Smell; Tracheotomy; Urethane

1997
Effects of scopolamine and hippocampal lesions on negative patterning discrimination performance in rats.
    Behavioral neuroscience, 1997, Volume: 111, Issue:6

    Topics: Animals; Cerebral Decortication; Choice Behavior; Conditioning, Operant; Cues; Discrimination Learning; Hippocampus; Male; Muscarinic Antagonists; N-Methylscopolamine; Rats; Rats, Inbred Strains; Reaction Time; Scopolamine

1997
Scopolamine prevents tolerance to the effects of caffeine on rotational behavior in 6-hydroxydopamine-denervated rats.
    European journal of pharmacology, 1999, Jan-29, Volume: 366, Issue:1

    Topics: Animals; Caffeine; Central Nervous System Stimulants; Dose-Response Relationship, Drug; Drug Tolerance; Functional Laterality; Male; Muscarinic Antagonists; N-Methylscopolamine; Nerve Degeneration; Oxidopamine; Parasympatholytics; Rats; Rats, Sprague-Dawley; Scopolamine; Sodium Chloride; Stereotyped Behavior

1999
Scopolamine disruption of behavioral and hippocampal responses in appetitive trace classical conditioning.
    Behavioural brain research, 1999, Volume: 100, Issue:1-2

    Topics: Age Factors; Animals; Appetitive Behavior; Conditioning, Classical; Hippocampus; Injections, Subcutaneous; Mastication; Muscarinic Antagonists; N-Methylscopolamine; Rabbits; Receptors, Cholinergic; Scopolamine

1999
Visuospatial attentional functioning in mice: interactions between cholinergic manipulations and genotype.
    The European journal of neuroscience, 1999, Volume: 11, Issue:8

    Topics: Animals; Attention; Behavior, Animal; Choice Behavior; Genotype; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Motor Activity; Muscarinic Antagonists; N-Methylscopolamine; Reaction Time; Scopolamine; Space Perception; Visual Perception

1999
Scopolamine and Pavlovian fear conditioning in rats: dose-effect analysis.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 1999, Volume: 21, Issue:6

    Topics: Acoustic Stimulation; Amygdala; Animals; Avoidance Learning; Conditioning, Classical; Dose-Response Relationship, Drug; Electroshock; Fear; Female; Long-Term Potentiation; N-Methylscopolamine; Rats; Rats, Long-Evans; Scopolamine

1999
Cloning and functional characterization of a Caenorhabditis elegans muscarinic acetylcholine receptor.
    Receptors & channels, 1999, Volume: 6, Issue:6

    Topics: Acetylcholine; Amino Acid Sequence; Animals; Atropine; Base Sequence; Binding, Competitive; Caenorhabditis elegans; Chloride Channels; CHO Cells; Cloning, Molecular; Cricetinae; Gene Expression; Ion Channel Gating; Ligands; Molecular Sequence Data; N-Methylscopolamine; Oxotremorine; Receptors, Muscarinic; Recombinant Proteins; Scopolamine; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Xenopus

1999
Effect of central and peripheral cholinergic antagonists on chlorpyrifos-induced changes in body temperature in the rat.
    Toxicology, 1999, Dec-20, Volume: 142, Issue:1

    Topics: Animals; Body Temperature; Chlorpyrifos; Cholinergic Fibers; Cholinesterase Inhibitors; Female; Fever; Hypothermia; Insecticides; Muscarinic Antagonists; N-Methylscopolamine; Rats; Rats, Long-Evans; Scopolamine

1999
Muscarinic cholinergic neuromodulation reduces proactive interference between stored odor memories during associative learning in rats.
    Behavioral neuroscience, 2000, Volume: 114, Issue:1

    Topics: Animals; Association Learning; Dose-Response Relationship, Drug; Male; Mental Recall; Muscarinic Antagonists; N-Methylscopolamine; Proactive Inhibition; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Retention, Psychology; Scopolamine; Smell; Synaptic Transmission

2000
Substance P and its transglutaminase-synthesized spermine derivative elicit yawning behavior via nitric oxide in rats.
    Peptides, 2001, Volume: 22, Issue:9

    Topics: Animals; Arginine; Behavior, Animal; Catheterization; Dose-Response Relationship, Drug; Drug Interactions; Indoles; Injections, Intraperitoneal; Isoindoles; Male; N-Methylscopolamine; Neurokinin-1 Receptor Antagonists; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Receptors, Neurokinin-1; Scopolamine; Stereoisomerism; Structure-Activity Relationship; Substance P; Substantia Nigra; Time Factors; Yawning

2001
Influence of benzodiazepine binding site ligands on fear-conditioned contextual memory.
    European journal of pharmacology, 2001, Aug-24, Volume: 426, Issue:1-2

    Topics: Animals; Azides; Benzodiazepines; Binding Sites; Binding, Competitive; Carbolines; Conditioning, Psychological; Convulsants; Fear; Flumazenil; GABA Antagonists; GABA Modulators; Imidazoles; Ligands; Male; Memory; Mice; Mice, Inbred C57BL; Motor Activity; N-Methylscopolamine; Piperazines; Quinolines; Receptors, GABA-A; Scopolamine; Silanes; Tritium

2001
Effects of molsidomine on scopolamine-induced amnesia and hypermotility in the rat.
    European journal of pharmacology, 2001, Aug-31, Volume: 426, Issue:3

    Topics: Amnesia; Animals; Avoidance Learning; Dose-Response Relationship, Drug; Male; Memory; Molsidomine; Motor Activity; Muscarinic Antagonists; N-Methylscopolamine; Rats; Scopolamine; Time Factors; Vasodilator Agents

2001
Central anticholinergics to treat nerve-agent poisoning.
    Lancet (London, England), 2002, Jan-19, Volume: 359, Issue:9302

    Topics: Animals; Antidotes; Atropine; Central Nervous System Agents; Chemical Warfare Agents; Cholinergic Antagonists; Cholinesterase Inhibitors; Mice; N-Methylscopolamine; Physostigmine; Scopolamine

2002
Muscarinic cholinergic receptor blockade impairs free fatty acid mobilization during fasting in pigeons (Columba livia).
    Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology, 2002, Volume: 172, Issue:2

    Topics: Animals; Blood Glucose; Carbachol; Cholinergic Agonists; Columbidae; Fasting; Fatty Acids, Nonesterified; Injections, Intraventricular; Lipolysis; Male; Muscarinic Antagonists; N-Methylscopolamine; Parasympatholytics; Receptors, Muscarinic; Scopolamine

2002
[Fatal effects of methylscopolamine nitrate administration in two cases of congenital pyloric stenosis].
    Nordisk medicin, 1952, Aug-01, Volume: 47, Issue:31

    Topics: Constriction, Pathologic; N-Methylscopolamine; Pyloric Stenosis; Pylorus; Scopolamine

1952
A comparison of some atropine-like drugs in man, with particular reference to their end-organ specificity.
    British journal of pharmacology and chemotherapy, 1958, Volume: 13, Issue:2

    Topics: Accommodation, Ocular; Atropine; Heart Rate; Humans; Male; Methantheline; N-Methylscopolamine; Organ Specificity; Parasympatholytics; Propantheline; Pupil; Quaternary Ammonium Compounds; Salivation; Scopolamine; Sweating

1958
EFFECT OF AN ANTI-ACETYLCHOLINE DRUG, METHSCOPOLAMINE BROMIDE, ON ULCER FORMATION AND GASTRIC MUCUS.
    The Journal of pharmacy and pharmacology, 1964, Volume: 16

    Topics: Acetylcholine; Bromides; Gastric Juice; Gastric Mucosa; Hexosamines; Mucus; N-Methylscopolamine; Parasympatholytics; Peptic Ulcer; Pharmacology; Rats; Research; Scopolamine; Ulcer

1964
The effect of methylscopolamine-nitrate (scopyle) on the stomach in hypertrophic stenosis of the pylorus; a roentgenological study.
    Acta paediatrica, 1949, Volume: 37, Issue:3-4

    Topics: Constriction, Pathologic; Humans; N-Methylscopolamine; Pylorus; Scopolamine; Stomach

1949
Effects of biasing the location of stimulus presentation, and the muscarinic cholinergic receptor antagonist scopolamine, on performance of a 5-choice serial reaction time attention task in rats.
    Behavioural pharmacology, 2006, Volume: 17, Issue:1

    Topics: Animals; Attention; Choice Behavior; Conditioning, Operant; Injections, Subcutaneous; Male; Muscarinic Antagonists; N-Methylscopolamine; Orientation; Pattern Recognition, Visual; Premedication; Probability Learning; Rats; Rats, Sprague-Dawley; Reaction Time; Scopolamine; Serial Learning

2006
Enhancing effects of nicotine and impairing effects of scopolamine on distinct aspects of performance in computerized attention and working memory tasks in marmoset monkeys.
    Neuropharmacology, 2006, Volume: 51, Issue:2

    Topics: Acetylcholine; Animals; Attention; Callithrix; Dose-Response Relationship, Drug; Female; Male; Memory; Motivation; Muscarinic Antagonists; N-Methylscopolamine; Nicotine; Nicotinic Agonists; Receptors, Muscarinic; Receptors, Nicotinic; Reinforcement Schedule; Reward; Scopolamine; Task Performance and Analysis

2006
A non-spatial, stimulus-comparison working memory task in rats and disruption by scopolamine.
    Neuroscience, 2007, Mar-30, Volume: 145, Issue:3

    Topics: Animals; Conditioning, Psychological; Dose-Response Relationship, Drug; Male; Memory; N-Methylscopolamine; Rats; Rats, Sprague-Dawley; Scopolamine; Time Factors

2007
Scopolamine induced deficits in a battery of rat cognitive tests: comparisons of sensitivity and specificity.
    Behavioural pharmacology, 2009, Volume: 20, Issue:3

    Topics: Acetylcholine; Animals; Attention; Behavior, Animal; Cholinergic Antagonists; Cognition; Male; Maze Learning; Mental Recall; N-Methylscopolamine; Psychomotor Performance; Rats; Rats, Long-Evans; Rats, Sprague-Dawley; Reinforcement, Psychology; Scopolamine; Sensitivity and Specificity; Space Perception

2009
Role of acetylcholine in negative patterning in turtles (Chrysemys picta).
    Behavioral neuroscience, 2009, Volume: 123, Issue:4

    Topics: Acetylcholine; Analysis of Variance; Animals; Cholinergic Antagonists; Learning; Muscarinic Antagonists; N-Methylscopolamine; Neuropsychological Tests; Photic Stimulation; Probability; Random Allocation; Scopolamine; Turtles

2009
Sensorimotor gating and vigilance-dependent choice accuracy: a within-subject correlative analysis in wild-type C57BL/6 mice.
    Behavioural brain research, 2011, Feb-02, Volume: 217, Issue:1

    Topics: Animals; Attention; Choice Behavior; Conditioning, Operant; Discrimination, Psychological; Dizocilpine Maleate; Male; Mice; Mice, Inbred C57BL; N-Methylscopolamine; Reflex, Startle; Scopolamine; Sensory Gating; Visual Perception

2011
The context preexposure facilitation effect in mice: a dose-response analysis of pretraining scopolamine administration.
    Behavioural brain research, 2011, Nov-20, Volume: 225, Issue:1

    Topics: Analysis of Variance; Animals; Cholinergic Antagonists; Conditioning, Classical; Dose-Response Relationship, Drug; Electroshock; Fear; Freezing Reaction, Cataleptic; Male; Mice; Mice, Inbred C57BL; N-Methylscopolamine; Reinforcement, Psychology; Scopolamine; Video Recording

2011
Reversal of scopolamine-induced disruption of prepulse inhibition by clozapine in mice.
    Pharmacology, biochemistry, and behavior, 2012, Volume: 101, Issue:1

    Topics: Acoustic Stimulation; Analysis of Variance; Animals; Antipsychotic Agents; Clozapine; Dose-Response Relationship, Drug; Male; Mice; Mice, Inbred C57BL; Muscarinic Antagonists; N-Methylscopolamine; Reflex, Startle; Reproducibility of Results; Scopolamine

2012
Pharmacological evidence is consistent with a prominent role of spatial memory in complex navigation.
    Proceedings. Biological sciences, 2016, Feb-10, Volume: 283, Issue:1824

    Topics: Age Factors; Animals; Central Nervous System; Muscarinic Antagonists; N-Methylscopolamine; Scopolamine; Spatial Memory; Spatial Navigation; Turtles

2016