Page last updated: 2024-08-25

n-methylscopolamine and pirenzepine

n-methylscopolamine has been researched along with pirenzepine in 142 studies

Research

Studies (142)

Timeframe	Studies, this research(%)	All Research%
pre-1990	69 (48.59)	18.7374
1990's	57 (40.14)	18.2507
2000's	9 (6.34)	29.6817
2010's	7 (4.93)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Pinkas-Kramarski, R; Sokolovsky, M; Stein, R	1
Hellman, U; Jolkkonen, M; Karlsson, E; van Giersbergen, PL; Wernstedt, C	1
Go, ML; Sim, MK; Xu, R	1
Bodor, N; Browne, CE; Buchwald, P; Farag, HH; Hochhaus, G; Huang, F; Ji, F; Wu, WM	1
Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S	1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K	1
Artymyshyn, R; Bird, ED; Cassanova, MF; Joyce, JN; Kim, SJ; Kleinman, JE; Lawrence, D; Lexow, N; Senzon, S; Winokur, A	1
Akerman, KE; Hämäläinen, H; Heikkilä, J; Kukkonen, J; Näsman, J; Ojala, P	1
Akerman, KE; Kukkonen, J	1
Drübbisch, V; Lameh, J; Philip, M; Sadée, W; Sharma, YK	1
Kajimura, M; Reuben, MA; Sachs, G	1
Ehlert, FJ; Thomas, EA	2
Flynn, DD; Mash, DC; Vaishnav, AA	1
Bellido, I; Garcia, AJ; Gómez, A; Marquez, E; Martos, F; Pavia, J; Sanchez de la Cuesta, F	1
Atkins, PT; Kitai, ST; Nishi, K; Surmeier, DJ	1
Gómez, A; Laukkonen, S; Marquez, E; Martos, F; Pavia, J; Sánchez de la Cuesta, F	1
Hersey, SJ; Kajimura, M; Sachs, G; Scott, DR; Wilkes, JM	1
Graybiel, AM; Nastuk, MA	2
Annis, SJ; Ehlert, FJ; Leslie, FM; Smith, TD	1
Yang, CM	1
Baumgold, J; Bradbury, BJ; Jacobson, KA; Karton, Y; Paek, R	1
Gomez, A; Laukonnen, S; Marquez, E; Martos, F; Pavia, J; Rius, F; Sanchez de la Cuesta, F	1
Bonner, TI; Brann, MR; Wess, J	1
Buckley, NJ; Lazareno, S; Roberts, FF	1
Hanack, C; Herawi, M; Kopp, R; Lambrecht, G; Moser, U; Mutschler, E; Pfeiffer, A; Tacke, R	1
Ehlert, FJ; Tran, LP	1
Fujimoto, K; Kawashima, K; Oohata, H; Suzuki, T	1
Delen, FM; Ehlert, FJ; Liem, HA; Yun, SH	1
Haga, T; Honda, N; Ichiyama, A; Kajimura, M; Kaneko, E	1
Alonso, R; Didier, M; Soubrie, P	1
Delmendo, RE; Lopez, M; Michel, AD; Whiting, RL	1
Kellar, KJ; Price, DL; Wagster, MV; Walker, LC; Whitehouse, PJ	1
Chiang, PK; Covington, J; Jackson, BW; Leader, H; Newman, AH; Oleshansky, M; Weissman, BA	1
Louie, DS; Owyang, C	1
Ackerman, MS; Korc, M; Roeske, WR	1
Hawthorne, JN; Simmonds, SH; Yagisawa, H	1
Horwitz, J	1
Ferrendelli, CA; Hanchett, HE; Hollifield, MA; Lorenzi, MV; Potter, LT	1
Ackerman, MS; Heck, RJ; Korc, M; Roeske, WR	1
Michel, AD; Stefanich, E; Whiting, RL	2
Palm, D; Pitschner, HF; Schlepper, M; Schulte, B; Wellstein, A	1
Biziere, K; Bourguignon, JJ; Feltz, P; Kan, JP; Michaud, JC; Schumacher, C; Steinberg, R; Wermuth, CG; Worms, P	1
Cross, AJ; Green, AR; Hunter, AJ; Jones, JA; Murray, TK	1
Delen, FM; Ehlert, FJ; Friedman, DJ; Self, DW; Yun, SH	1
Michel, AD; Whiting, RL	2
Cornett, CM; Eglen, RM; Kunysz, EA; Michel, AD; Whiting, RL	1
Brown, DA; Marrion, NV; Marsh, SJ; Smart, TG	1
Ek, B; Nahorski, S	1
Amrhein, CL; Cioffi, CL; el-Fakahany, EE; McKinney, M; Richelson, E; Stenstrom, S; Surichamorn, W	1
Cioffi, CL; el-Fakahany, EE	2
Anderson, W; Dickinson, KE; Hirschowitz, BI; Matsumoto, H; Pruitt, RE; Uemura, N	1
Covington, S; Ertan, A; McCord, R; Ozden, A; Rice, J; Rossowski, WJ	1
Kunysz, EA; Michel, AD; Whiting, RL; Woods, K	1
Delmendo, RE; Michel, AD; Whiting, RL	1
McKinney, M; Richelson, E; Stenstrom, S	1
McKinney, M; Richelson, E	1
Chuang, DM; Xu, J	1
Camus, J; Christophe, J; Waelbroeck, M; Winand, J	1
Miranda, HI; Silva, WI; Wolstenholme, WW	1
Garcia, A; Giraldo, E; Gomez, A; Ladinsky, H; Martos, F; Sanchez de La Cuesta, F; Vigano, MA	1
Beer, MS; Freedman, SB; Harley, EA	1
Franklin, SR; Tang, AH	1
el-Fakahany, EE; Kim, ON; Lai, WS; Lee, NH; Surichamorn, W	1
Auriga, C; Birdsall, NJ; Boer, R; Schudt, C	1
Abdel-Latif, AA; Honkanen, RE	1
Martin, DS; McNeill, JR	1
Birdsall, NJ; Blessed, G; Bonham, JR; Candy, JM; Dick, DJ; Fairbairn, A; Johnson, M; Perry, EK; Perry, RH; Smith, CJ	1
Dwyer, TM; Farley, JM; Yang, CM	1
Giraldo, E; Hammer, R; Ladinsky, H; Viganò, MA	1
Cuevas, N; Miranda, HF; Silva, WI; Wolstenholme, WW	1
Bali, JP; Baudiere, B; Giraldo, E; Ladinsky, H; Monferini, E	1
De Paoli, AM; Giraldo, E; Hammer, R; Martos, F; Monferini, E	1
Dvorkin, B; Larocca, JN; Ledeen, RW; Makman, MH	1
Lauterbach, F	1
Cortés, R; Cymerman, U; Palacios, JM; Skangiel-Kramska, J	1
Cortés, R; Palacios, JM; Probst, A; Tobler, HJ	1
Gremillion, MA; Klein, WL; Lambert, MP; Large, TH	1
Birdsall, NJ; Hulme, EC; Keen, M	1
Giraldo, E; Hammer, R; Ladinsky, H; Monferini, E; Schiavi, GB	1
Christophe, J; Gillard, M; Waelbroeck, M	1
el-Fakahany, EE; Lai, WS; Ramkumar, V	1
el-Fakahany, EE; Lai, WS	1
Blaker, SN; Creese, I; Norman, AB; Thal, L	1
Giraldo, E; Hammer, R; Monferini, E	1
Aronstam, RS; Kirby, ML; Smith, MD	1
el-Fakahany, EE; Lee, JH	1
Bali, JP; Baudiere, B; Magous, R	1
Ehlert, FJ; Jenden, DJ	1
Birdsall, NJ; Caulfield, MP; Cross, AJ; Crow, T; Straughan, DW	1
Cross, AJ; Frith, C; Johnson, JA; Taylor, GR	1
Daniotti, S; Del Soldato, P	1
Baissat, J; Chassaing, C; Duchêne-Marullaz, P; Dureng, G	1
Albinus, M; Winne, D	1
Bárány, E; Berrie, CP; Birdsall, NJ; Burgen, AS; Hulme, EC	1
Hammer, R	2
Bernabeu, R; Cerveñansky, C; Izquierdo, I; Jerusalinsky, D; Kornisiuk, E	1
Baylis, HA; Bunting, R; Mason, WT; Millar, NS; Reaper, C; Sattelle, DB	1
Baghdoyan, HA; Lydic, R; Mallios, VJ	1
Wells, JW; Wreggett, KA	1
Bellido, I; Gomez, A; Sanchez de la Cuesta, F	1
Baghdoyan, HA; Duckrow, RB; Mallios, VJ; Mash, DC	1
Jakubík, J; Tucek, S	1
Camus, J; Feifel, R; Lambrecht, G; Mutschler, E; Rafeiner, K; Rodrigues de Miranda, JF; Strohmann, C; Tacke, R; Tastenoy, M; Waelbroeck, M	1
Adem, A; Hellman, U; Jolkkonen, M; Karlsson, E; Kumlin, E; Satyapan, N; Wernstedt, C	1
Chen, FF; Hsu, HF; Sung, TC; Wu, D; Yang, CM	1
Greten, H; Mirau, S; Raedler, A; Sievers, J; von Schrenck, T	1
Kramss, RH; Mangano, RM; Trybulski, EJ; Zhang, J	1
Antonsson, BM; Ek, B	1
Cappello, B; Di Carlo, R; Greco, G; Meli, R; Muccioli, G; Novellino, E; Perissutti, E; Santagada, V; Silipo, C; Vittoria, A	1
Eglen, RM; Sharif, NA; To, ZP	1
Consolo, S; Garcia Ruiz, AJ; La Porta, C; Ladinsky, H; Zambelli, M	1
Bacáková, L; el-Fakahany, EE; Jakubík, J; Tucek, S	1
Jones, SB; King, LB	1
Barbier, P; Corsini, GU; Di Bugno, C; Fornai, F; Maggio, R; Renzetti, AR; Turbanti, L; Vaglini, F	1
Adem, A; Cowburn, RF; Lannfelt, L; Venizelos, N; Vestling, M; Winblad, B	1
Alemán, V; del Guante, MA; Ortega, A; Prado-Alcalá, RA	1
Bertellotti, L; Boraschi, P; Braccini, G; Marraccini, P; Marrucci, A; Testa, R	1
Baghdoyan, HA	1
Potter, LT; Purkerson, SL	1
Christopoulos, A; El-Fakahany, EE; Parsons, AM	1
Berlan, M; Galitzky, J; Merial, C; Montastruc, JL; Pelat, M; Senard, JM; Verwaerde, P	1
Novelli, F; Sparatore, A; Sparatore, F; Tasso, B	1
Bymaster, FP; Falcone, JF	1
Dauphin, F; Deagostino, A; Desbène, PL; Ducandas, C; Lasne, MC; Martin, J; Morin, C; Perrio, C	1
Ehlert, FJ; Lambrecht, G; Sawyer, GW	1
Christopoulos, A; Lanzafame, A; Mitchelson, F	1
Ehlert, FJ; Griffin, MT; Hsu, JC; Shehnaz, D	1
Arias-Montaño, JA; Sánchez-Lemus, E	1
Blackstone, K; Pratt, WE	1
Christopoulos, A; Sexton, PM; Stewart, GD	1
Fujino, T; Kageyama, A; Nozawa, Y; Yamada, S; Yoshida, A	1
Anisuzzaman, AS; Muramatsu, I; Nishimune, A; Uwada, J; Yoshiki, H	1
Anisuzzaman, ASM; Morishima, S; Muramatsu, I; Uwada, J; Yoshiki, H	1
Conn, PJ; Dean, B; Hopper, S; Scarr, E	1
Hirata, K; Horita, S; Iwata, S; Kinoshita, M; Kobayashi, T; Kobilka, BK; Lee, S; Maeda, S; Murata, T; Suno, R; Tawaramoto, MS; Tsujimoto, H; Vaidehi, N; Yamamoto, M; Yamashita, K; Yasuda, S	1

Reviews

1 review(s) available for n-methylscopolamine and pirenzepine

Article	Year
Cardioselective muscarinic antagonists. Federation proceedings, 1987, Volume: 46, Issue:8 Topics: Animals; Carbachol; Cardiotonic Agents; Carrier Proteins; Cyclic AMP; Cyclic AMP Receptor Protein; Dose-Response Relationship, Drug; Heart; N-Methylscopolamine; Oxotremorine; Phorbol Esters; Pirenzepine; Receptors, Adrenergic; Receptors, Cholinergic; Receptors, Muscarinic; Scopolamine Derivatives	1987

Trials

1 trial(s) available for n-methylscopolamine and pirenzepine

Article	Year
[Usefulness of pirenzepine in the study of the upper digestive tract and the large intestine with double contrast media: comparison with scopolamine methylbromide]. La Radiologia medica, 1996, Volume: 92, Issue:6 Topics: Adult; Aged; Aged, 80 and over; Butylscopolammonium Bromide; Contrast Media; Female; Gastrointestinal Diseases; Heart Rate; Humans; Male; Middle Aged; Muscarinic Antagonists; N-Methylscopolamine; Pirenzepine; Radiography; Scopolamine Derivatives; Single-Blind Method	1996

Article

Year

[Usefulness of pirenzepine in the study of the upper digestive tract and the large intestine with double contrast media: comparison with scopolamine methylbromide].

La Radiologia medica, 1996, Volume: 92, Issue:6

Topics: Adult; Aged; Aged, 80 and over; Butylscopolammonium Bromide; Contrast Media; Female; Gastrointestinal Diseases; Heart Rate; Humans; Male; Middle Aged; Muscarinic Antagonists; N-Methylscopolamine; Pirenzepine; Radiography; Scopolamine Derivatives; Single-Blind Method

1996

Other Studies

140 other study(ies) available for n-methylscopolamine and pirenzepine

Article	Year
Cloned M1 muscarinic receptors mediate both adenylate cyclase inhibition and phosphoinositide turnover. The EMBO journal, 1988, Volume: 7, Issue:10 Topics: Acetylcholine; Adenylyl Cyclase Inhibitors; Animals; Atropine; Carbachol; Cell Line; Cloning, Molecular; GTP-Binding Proteins; Oxotremorine; Phosphatidylinositols; Rats; Receptors, Muscarinic; Recombinant Proteins	1988
A toxin from the green mamba Dendroaspis angusticeps: amino acid sequence and selectivity for muscarinic m4 receptors. FEBS letters, 1994, Sep-19, Volume: 352, Issue:1 Topics: Alkaloids; Amino Acid Sequence; Amino Acids; Animals; Elapid Venoms; Elapidae; Furans; Intercellular Signaling Peptides and Proteins; Kinetics; Molecular Sequence Data; Naphthalenes; Peptides; Piperidines; Pirenzepine; Receptors, Muscarinic; Sequence Analysis	1994
Synthesis and pharmacological characterization of O-alkynyloximes of tropinone and N-methylpiperidinone as muscarinic agonists. Journal of medicinal chemistry, 1998, Aug-13, Volume: 41, Issue:17 Topics: Animals; Aorta; Binding, Competitive; Drug Design; Escape Reaction; In Vitro Techniques; Male; Maze Learning; Mice; Models, Molecular; Molecular Structure; Muscarinic Agonists; Muscle Contraction; Muscle, Smooth, Vascular; N-Methylscopolamine; Nuclear Magnetic Resonance, Biomolecular; Piperidines; Pirenzepine; Rabbits; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Structure-Activity Relationship; Tropanes	1998
Receptor binding studies of soft anticholinergic agents. AAPS pharmSci, 2001, Volume: 3, Issue:4 Topics: Animals; Cholinergic Antagonists; Dose-Response Relationship, Drug; Drug Stability; Guinea Pigs; Humans; Ileum; Protein Binding; Quantitative Structure-Activity Relationship; Receptors, Muscarinic	2001
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain. Bioorganic & medicinal chemistry, 2009, Oct-01, Volume: 17, Issue:19 Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship	2009
QSAR-based permeability model for drug-like compounds. Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8 Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2011
Distribution of beta-adrenergic receptor subtypes in human post-mortem brain: alterations in limbic regions of schizophrenics. Synapse (New York, N.Y.), 1992, Volume: 10, Issue:3 Topics: Adult; Autopsy; Autoradiography; Brain; Cell Membrane; Female; Humans; Imipramine; Iodine Radioisotopes; Limbic System; Male; Middle Aged; N-Methylscopolamine; Organ Specificity; Pindolol; Pirenzepine; Receptors, Adrenergic, beta; Schizophrenia; Scopolamine Derivatives; Serotonin Antagonists; Suicide; Tritium	1992
Muscarinic receptor subtypes in human neuroblastoma cell lines SH-SY5Y and IMR-32 as determined by receptor binding, Ca++ mobilization and northern blotting. The Journal of pharmacology and experimental therapeutics, 1992, Volume: 263, Issue:3 Topics: Blotting, Northern; Calcium; Humans; N-Methylscopolamine; Neuroblastoma; Phosphatidylinositols; Piperidines; Pirenzepine; Radioligand Assay; Receptors, Muscarinic; RNA, Messenger; Scopolamine Derivatives; Tumor Cells, Cultured	1992
Apparent noncompetitive antagonism of muscarinic receptor mediated Ca2+ mobilization by some muscarinic antagonists. Biochemical and biophysical research communications, 1992, Dec-15, Volume: 189, Issue:2 Topics: Atropine; Calcium; Fura-2; Humans; Kinetics; Muscarinic Antagonists; N-Methylscopolamine; Neuroblastoma; Parasympatholytics; Piperidines; Pirenzepine; Receptors, Muscarinic; Scopolamine Derivatives; Spectrometry, Fluorescence; Tumor Cells, Cultured	1992
Mapping the ligand binding pocket of the human muscarinic cholinergic receptor Hm1: contribution of tyrosine-82. Pharmaceutical research, 1992, Volume: 9, Issue:12 Topics: Amino Acid Sequence; Binding, Competitive; Cells, Cultured; Female; GTP-Binding Proteins; Humans; Kidney; Ligands; Molecular Sequence Data; N-Methylscopolamine; Pirenzepine; Point Mutation; Pregnancy; Protein Binding; Receptors, Cholinergic; Scopolamine Derivatives; Transfection; Tyrosine	1992
The muscarinic receptor gene expressed in rabbit parietal cells is the m3 subtype. Gastroenterology, 1992, Volume: 103, Issue:3 Topics: Animals; Atropine; Base Sequence; Blotting, Southern; Molecular Sequence Data; N-Methylscopolamine; Parietal Cells, Gastric; Piperidines; Pirenzepine; Polymerase Chain Reaction; Rabbits; Receptors, Muscarinic; RNA, Messenger; Scopolamine Derivatives	1992
Irreversible effects of 4-DAMP mustard on muscarinic receptors in vivo. Proceedings of the Western Pharmacology Society, 1992, Volume: 35 Topics: Alkylating Agents; Animals; Diphenylacetic Acids; Male; N-Methylscopolamine; Parasympatholytics; Piperidines; Pirenzepine; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Scopolamine Derivatives	1992
Interactions of cocaine with primary and secondary recognition sites on muscarinic receptors. Molecular pharmacology, 1992, Volume: 41, Issue:4 Topics: Adult; Allosteric Site; Binding Sites; Brain Stem; Carbachol; Cocaine; Ethylmaleimide; Guanine Nucleotides; Humans; In Vitro Techniques; Kinetics; Male; N-Methylscopolamine; Pirenzepine; Receptors, Muscarinic; Scopolamine Derivatives	1992
Muscarinic receptor subtypes in human and rat colon smooth muscle. Biochemical pharmacology, 1992, Jun-09, Volume: 43, Issue:11 Topics: Animals; Atropine; Binding, Competitive; Colon; Humans; Infant, Newborn; Male; Muscle, Smooth; N-Methylscopolamine; Pirenzepine; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Scopolamine Derivatives	1992
Muscarinic regulation of cyclic AMP metabolism in rat neostriatal cultures. Brain research, 1990, Nov-26, Volume: 534, Issue:1-2 Topics: 1-Methyl-3-isobutylxanthine; Animals; Carbachol; Cells, Cultured; Corpus Striatum; Cyclic AMP; Embryo, Mammalian; Kinetics; N-Methylscopolamine; Neurons; Parasympatholytics; Pirenzepine; Rats; Receptors, Muscarinic; Scopolamine Derivatives	1990
M1 and M3 muscarinic receptor subtypes in rat forebrain. Methods and findings in experimental and clinical pharmacology, 1991, Volume: 13, Issue:10 Topics: Animals; Binding Sites; Cells, Cultured; Kinetics; Male; N-Methylscopolamine; Parasympatholytics; Pirenzepine; Prosencephalon; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Scopolamine Derivatives	1991
Muscarinic responses of gastric parietal cells. The Journal of membrane biology, 1991, Volume: 122, Issue:2 Topics: Aminopyrine; Animals; Arachidonic Acids; Calcium; Carbachol; Glucose; Image Processing, Computer-Assisted; Ionomycin; N-Methylscopolamine; Parasympatholytics; Parietal Cells, Gastric; Piperidines; Pirenzepine; Rabbits; Receptors, Muscarinic; Scopolamine Derivatives; Tritium	1991
Pharmacologically defined M1 and M2 muscarinic cholinergic binding sites in the cat's substantia nigra: development and maturity. Brain research. Developmental brain research, 1991, Jul-16, Volume: 61, Issue:1 Topics: Animals; Animals, Newborn; Autoradiography; Binding, Competitive; Cats; Fetus; Gestational Age; N-Methylscopolamine; Parasympatholytics; Pirenzepine; Receptors, Muscarinic; Scopolamine Derivatives; Substantia Nigra; Tritium	1991
N-[3H]methylscopolamine labeling of non-M1, non-M2 muscarinic receptor binding sites in rat brain. The Journal of pharmacology and experimental therapeutics, 1991, Volume: 256, Issue:3 Topics: Animals; Autoradiography; Binding Sites; Brain; Drug Interactions; Male; N-Methylscopolamine; Parasympatholytics; Pirenzepine; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Scopolamine Derivatives	1991
Characterization of muscarinic receptors in dog tracheal smooth muscle cells. Journal of autonomic pharmacology, 1991, Volume: 11, Issue:1 Topics: Animals; Atropine; Carbachol; Diamines; Dogs; In Vitro Techniques; Kinetics; Muscle, Smooth; N-Methylscopolamine; Parasympatholytics; Piperidines; Pirenzepine; Receptors, Muscarinic; Scopolamine Derivatives; Trachea	1991
Functionalized congener approach to muscarinic antagonists: analogues of pirenzepine. Journal of medicinal chemistry, 1991, Volume: 34, Issue:7 Topics: Animals; Binding Sites; Binding, Competitive; Cell Membrane; Chemical Phenomena; Chemistry; N-Methylscopolamine; Parasympatholytics; Piperazines; Pirenzepine; Rats; Receptors, Muscarinic; Scopolamine Derivatives; Structure-Activity Relationship	1991
Circadian rhythm in muscarinic receptor subtypes in rat forebrain. Chronobiology international, 1990, Volume: 7, Issue:4 Topics: Animals; Brain; Carbachol; Circadian Rhythm; In Vitro Techniques; Kinetics; Male; N-Methylscopolamine; Pirenzepine; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Scopolamine Derivatives	1990
Chimeric m2/m3 muscarinic receptors: role of carboxyl terminal receptor domains in selectivity of ligand binding and coupling to phosphoinositide hydrolysis. Molecular pharmacology, 1990, Volume: 38, Issue:6 Topics: Animals; Cells, Cultured; Diamines; Hydrolysis; Ligands; N-Methylscopolamine; Phosphatidylinositols; Pirenzepine; Receptors, Muscarinic; Scopolamine Derivatives; Structure-Activity Relationship	1990
Characterization of muscarinic M4 binding sites in rabbit lung, chicken heart, and NG108-15 cells. Molecular pharmacology, 1990, Volume: 38, Issue:6 Topics: Animals; Chickens; Glioma; Guanylyl Imidodiphosphate; In Vitro Techniques; Kinetics; Lung; Male; Myocardium; N-Methylscopolamine; Neuroblastoma; Pirenzepine; Rabbits; Rats; Receptors, Muscarinic; RNA, Messenger; Scopolamine Derivatives; Species Specificity; Tumor Cells, Cultured	1990
Human gastric mucosa expresses glandular M3 subtype of muscarinic receptors. Digestive diseases and sciences, 1990, Volume: 35, Issue:12 Topics: Carbachol; Gastric Mucosa; Humans; In Vitro Techniques; N-Methylscopolamine; Parasympatholytics; Piperazines; Piperidines; Pirenzepine; Receptors, Muscarinic; Scopolamine Derivatives	1990
Regional distribution of M1, M2 and non-M1, non-M2 subtypes of muscarinic binding sites in rat brain. The Journal of pharmacology and experimental therapeutics, 1990, Volume: 255, Issue:3 Topics: Animals; Binding Sites; Binding, Competitive; Brain; Cerebral Cortex; Choline; Kinetics; Male; N-Methylscopolamine; Parasympatholytics; Pirenzepine; Quinuclidinyl Benzilate; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Scopolamine Derivatives; Tritium	1990
Pharmacological differentiation of presynaptic M1 muscarinic receptors modulating acetylcholine release from postsynaptic muscarinic receptors in guinea-pig ileum. General pharmacology, 1990, Volume: 21, Issue:1 Topics: Acetylcholine; Animals; Guinea Pigs; Ileum; In Vitro Techniques; Muscle, Smooth; N-Methylscopolamine; Parasympatholytics; Pirenzepine; Receptors, Muscarinic; Scopolamine Derivatives; Synapses	1990
The interaction of amitriptyline, doxepin, imipramine and their N-methyl quaternary ammonium derivatives with subtypes of muscarinic receptors in brain and heart. The Journal of pharmacology and experimental therapeutics, 1990, Volume: 253, Issue:1 Topics: Adenylyl Cyclase Inhibitors; Amitriptyline; Animals; Brain; Doxepin; Heart; Imipramine; In Vitro Techniques; Male; N-Methylscopolamine; Oxotremorine; Pirenzepine; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Scopolamine Derivatives	1990
Carbachol-induced potentiation and inhibition of acid secretion by guinea pig gastric gland. European journal of pharmacology, 1990, Mar-13, Volume: 178, Issue:1 Topics: Aminopyrine; Animals; Atropine; Binding, Competitive; Carbachol; Dose-Response Relationship, Drug; Gastric Acid; Gastric Mucosa; Guinea Pigs; Histamine; In Vitro Techniques; Male; N-Methylscopolamine; Parasympathomimetics; Pirenzepine; Receptors, Muscarinic; Scopolamine Derivatives	1990
[3H]N-methylscopolamine binding studies reveal M2 and M3 muscarinic receptor subtypes on cerebellar granule cells in primary culture. Journal of neurochemistry, 1990, Volume: 55, Issue:1 Topics: Animals; Atropine; Binding, Competitive; Cell Survival; Cells, Cultured; Cerebellum; Diamines; Granulocytes; N-Methylscopolamine; Parasympatholytics; Piperidines; Pirenzepine; Receptors, Muscarinic; Scopolamine Derivatives; Tritium	1990
On the interaction of gallamine with muscarinic receptor subtypes. European journal of pharmacology, 1990, Jul-03, Volume: 182, Issue:2 Topics: Animals; Binding, Competitive; Cells, Cultured; Chickens; Culture Techniques; Diamines; Female; Gallamine Triethiodide; Guinea Pigs; Heart; Humans; Kinetics; Membranes; Myocardium; N-Methylscopolamine; Pirenzepine; Rats; Receptors, Muscarinic; Scopolamine Derivatives	1990
Laminar organization and age-related loss of cholinergic receptors in temporal neocortex of rhesus monkey. The Journal of neuroscience : the official journal of the Society for Neuroscience, 1990, Volume: 10, Issue:9 Topics: Aging; Animals; Autoradiography; Macaca mulatta; N-Methylscopolamine; Oxotremorine; Pirenzepine; Receptors, Cholinergic; Receptors, Muscarinic; Receptors, Nicotinic; Scopolamine Derivatives; Temporal Lobe; Tissue Distribution	1990
Aprophit: an irreversible antagonist for muscarinic receptors. Biochemical pharmacology, 1990, Sep-15, Volume: 40, Issue:6 Topics: Adrenal Glands; Animals; Atropine; Binding, Competitive; Brain; Catecholamines; Guinea Pigs; Male; N-Methylscopolamine; Parasympatholytics; Phenylpropionates; Pirenzepine; Rats; Receptors, Muscarinic; Scopolamine Derivatives; Thiocyanates	1990
Muscarinic receptor subtypes on rat pancreatic acini: secretion and binding studies. The American journal of physiology, 1986, Volume: 251, Issue:2 Pt 1 Topics: Acetylcholine; Amylases; Animals; Benzodiazepinones; Binding Sites; Male; N-Methylscopolamine; Pancreas; Piperidines; Pirenzepine; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Scopolamine Derivatives; Tritium	1986
A cholinergic antagonist identifies a subclass of muscarinic receptors in isolated rat pancreatic acini. The Journal of pharmacology and experimental therapeutics, 1987, Volume: 240, Issue:1 Topics: Amylases; Animals; Atropine; Carbachol; Cerebral Cortex; Dose-Response Relationship, Drug; Kinetics; Male; Myocardium; N-Methylscopolamine; Pancreas; Pirenzepine; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Scopolamine Derivatives	1987
The muscarinic receptor of rat pituitary GH3 cells is coupled with adenylate cyclase inhibition, but not with phosphoinositide turnover. Biochemical pharmacology, 1988, Jul-01, Volume: 37, Issue:13 Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Animals; Carbachol; Inositol Phosphates; N-Methylscopolamine; Phosphatidylinositols; Pirenzepine; Pituitary Gland; Rats; Receptors, Muscarinic; Scopolamine Derivatives; Thyrotropin-Releasing Hormone; Tumor Cells, Cultured	1988
Muscarinic receptor stimulation increases inositol-phospholipid metabolism and inhibits cyclic AMP accumulation in PC12 cells. Journal of neurochemistry, 1989, Volume: 53, Issue:1 Topics: Animals; Cyclic AMP; Muscarine; N-Methylscopolamine; Pheochromocytoma; Phorbol Esters; Phosphatidylinositols; Phosphodiesterase Inhibitors; Pirenzepine; Protein Kinase C; Receptors, Muscarinic; Scopolamine Derivatives; Stimulation, Chemical; Tumor Cells, Cultured	1989
Tetrahydroaminoacridine and other allosteric antagonists of hippocampal M1 muscarine receptors. Molecular pharmacology, 1989, Volume: 35, Issue:5 Topics: Allosteric Regulation; Aminoacridines; Animals; Ethylmaleimide; Guanylyl Imidodiphosphate; Hippocampus; In Vitro Techniques; N-Methylscopolamine; Parasympatholytics; Pirenzepine; Protein Conformation; Rabbits; Receptors, Muscarinic; Scopolamine Derivatives; Solubility; Tacrine	1989
Identification and characterization of muscarinic receptors in cultured human pancreatic carcinoma cells. Pancreas, 1989, Volume: 4, Issue:3 Topics: Atropine; Carbachol; Cell Line; Humans; Inositol Phosphates; Kinetics; N-Methylscopolamine; Pancreatic Neoplasms; Parasympatholytics; Pirenzepine; Receptors, Muscarinic; Scopolamine Derivatives; Tumor Cells, Cultured	1989
PC12 phaeochromocytoma cells contain an atypical muscarinic receptor binding site. British journal of pharmacology, 1989, Volume: 97, Issue:3 Topics: Adrenal Gland Neoplasms; Animals; Binding, Competitive; Cell Membrane; Kinetics; Myocardium; N-Methylscopolamine; Parasympatholytics; Parasympathomimetics; Pheochromocytoma; Pirenzepine; Quinuclidinyl Benzilate; Rats; Receptors, Muscarinic; Scopolamine Derivatives; Submandibular Gland; Tumor Cells, Cultured	1989
AF-DX 116 discriminates heart from gland M2-cholinoceptors in man. Life sciences, 1989, Volume: 45, Issue:6 Topics: Adult; Animals; Atropine; Blood Pressure; Cattle; Cell Membrane; Cerebral Cortex; Heart Rate; Humans; Kinetics; Male; Myocardium; N-Methylscopolamine; Organ Specificity; Pirenzepine; Propranolol; Receptors, Cholinergic; Reference Values; Saliva; Salivary Glands; Scopolamine Derivatives; Swine	1989
Pharmacological characterization of the aminopyridazine SR 95639A, a selective M1 muscarinic agonist. European journal of pharmacology, 1989, Jul-18, Volume: 166, Issue:2 Topics: Animals; Behavior, Animal; Cisterna Magna; Dose-Response Relationship, Drug; Electrophysiology; Guinea Pigs; In Vitro Techniques; Injections; Male; Morpholines; Muscle Relaxation; N-Methylscopolamine; Parasympathomimetics; Pirenzepine; Pyridazines; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Scopolamine Derivatives; Stereotyped Behavior	1989
The cholinergic pharmacology of tetrahydroaminoacridine in vivo and in vitro. British journal of pharmacology, 1989, Volume: 98, Issue:1 Topics: Aminoacridines; Animals; Behavior, Animal; Brain Chemistry; Cholinesterase Inhibitors; Gallamine Triethiodide; In Vitro Techniques; Male; Mice; Myocardium; N-Methylscopolamine; Nicotine; Oxotremorine; Parasympathetic Nervous System; Physostigmine; Pirenzepine; Rats; Receptors, Muscarinic; Scopolamine Derivatives; Tacrine	1989
Direct labeling of rat M3-muscarinic receptors by [3H]4DAMP. European journal of pharmacology, 1989, Aug-03, Volume: 166, Issue:3 Topics: Adamantane; Animals; Binding, Competitive; Cerebral Cortex; In Vitro Techniques; Ligands; N-Methylscopolamine; Pirenzepine; Proteins; Rats; Receptors, Muscarinic; Scopolamine Derivatives; Submandibular Gland	1989
Coupling of subtypes of the muscarinic receptor to adenylate cyclase in the corpus striatum and heart. The Journal of pharmacology and experimental therapeutics, 1989, Volume: 251, Issue:2 Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Binding, Competitive; Corpus Striatum; Gallamine Triethiodide; Male; Myocardium; N-Methylscopolamine; Oxotremorine; Pirenzepine; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Muscarinic; RNA, Messenger; Scopolamine Derivatives	1989
Radioligand binding characteristics of the chicken cardiac muscarinic receptor. Naunyn-Schmiedeberg's archives of pharmacology, 1989, Volume: 340, Issue:3 Topics: Animals; Binding, Competitive; Cell Line; Cerebral Cortex; Chickens; In Vitro Techniques; Kinetics; Myocardium; N-Methylscopolamine; Parasympatholytics; Pirenzepine; Radioligand Assay; Rats; Receptors, Muscarinic; Scopolamine Derivatives; Submandibular Gland	1989
The interaction of hexamethonium with muscarinic receptor subtypes in vitro. British journal of pharmacology, 1989, Volume: 98, Issue:2 Topics: Animals; Carbachol; Diamines; Guinea Pigs; Hexamethonium Compounds; In Vitro Techniques; Kinetics; Muscle Contraction; Muscle, Smooth, Vascular; Myocardium; N-Methylscopolamine; Pirenzepine; Potassium Chloride; Receptors, Muscarinic; Scopolamine Derivatives; Submandibular Gland	1989
Muscarinic suppression of the M-current in the rat sympathetic ganglion is mediated by receptors of the M1-subtype. British journal of pharmacology, 1989, Volume: 98, Issue:2 Topics: Animals; Calcium; Gallamine Triethiodide; Ganglia, Spinal; Ganglia, Sympathetic; Ileum; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; N-Methylscopolamine; Piperidines; Pirenzepine; Potassium Channels; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Scopolamine Derivatives	1989
Muscarinic receptor coupling to inositol phospholipid metabolism in guinea-pig cerebral cortex, parotid gland and ileal smooth muscle. Biochemical pharmacology, 1988, Dec-01, Volume: 37, Issue:23 Topics: Animals; Atropine; Carbachol; Cerebral Cortex; Guanosine Triphosphate; Guinea Pigs; Ileum; Muscle, Smooth; N-Methylscopolamine; Oxotremorine; Parotid Gland; Phosphatidylinositols; Pirenzepine; Receptors, Muscarinic; Scopolamine Derivatives	1988
Pseudo-noncompetitive antagonism of muscarinic receptor-mediated cyclic GMP formation and phosphoinositide hydrolysis by pirenzepine. The Journal of pharmacology and experimental therapeutics, 1988, Volume: 247, Issue:3 Topics: Animals; Atropine; Carbachol; Cyclic GMP; Hydrolysis; Mice; N-Methylscopolamine; Phosphatidylinositols; Pirenzepine; Receptors, Muscarinic; Scopolamine Derivatives	1988
Lack of alterations in muscarinic receptor subtypes and phosphoinositide hydrolysis upon acute DFP treatment. European journal of pharmacology, 1988, Oct-26, Volume: 156, Issue:1 Topics: Animals; Cerebral Cortex; Hydrolysis; In Vitro Techniques; Isoflurophate; Male; Mice; Mice, Inbred ICR; N-Methylscopolamine; Parasympatholytics; Phosphatidylinositols; Pirenzepine; Receptors, Muscarinic; Scopolamine Derivatives	1988
Muscarinic cholinergic receptor subtype on frog esophageal peptic cells: binding and secretion studies. The Journal of pharmacology and experimental therapeutics, 1988, Volume: 246, Issue:3 Topics: Acetylcholine; Animals; Atropine; Bethanechol; Bethanechol Compounds; Carbachol; Esophagus; Imipramine; Kinetics; N-Methylscopolamine; Oxotremorine; Pepsinogens; Pirenzepine; Propranolol; Radioligand Assay; Rana catesbeiana; Receptors, Muscarinic; Scopolamine Derivatives	1988
Alterations in cholinergic muscarinic and somatostatin binding sites in a patient with idiopathic intestinal pseudo-obstruction. The American journal of the medical sciences, 1988, Volume: 296, Issue:6 Topics: Adult; Binding Sites; Electrophoresis, Polyacrylamide Gel; Humans; Intestinal Pseudo-Obstruction; Jejunum; Male; Membranes; N-Methylscopolamine; Pirenzepine; Receptors, Muscarinic; Receptors, Neurotransmitter; Receptors, Somatostatin; Scopolamine Derivatives; Somatostatin	1988
The human astrocytoma cell line 1321 N1 contains M2-glandular type muscarinic receptors linked to phosphoinositide turnover. British journal of pharmacology, 1989, Volume: 96, Issue:2 Topics: Animals; Astrocytoma; Binding, Competitive; Humans; Inositol Phosphates; Male; N-Methylscopolamine; Pirenzepine; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Scopolamine Derivatives; Sugar Phosphates; Tumor Cells, Cultured	1989
Affinity of muscarinic receptor antagonists for three putative muscarinic receptor binding sites. British journal of pharmacology, 1989, Volume: 96, Issue:2 Topics: Animals; Buffers; Cerebral Cortex; In Vitro Techniques; Male; Myocardium; N-Methylscopolamine; Parasympatholytics; Piperidines; Pirenzepine; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Scopolamine Derivatives; Submandibular Gland	1989
Muscarinic responses and binding in a murine neuroblastoma clone (N1E-115). Mediation of separate responses by high affinity and low affinity agonist-receptor conformations. Molecular pharmacology, 1985, Volume: 27, Issue:2 Topics: Animals; Benzodiazepinones; Carbachol; Clone Cells; Cyclic AMP; Cyclic GMP; Kinetics; Mice; N-Methylscopolamine; Neuroblastoma; Pirenzepine; Protein Conformation; Receptors, Muscarinic; Scopolamine Derivatives	1985
Short-term desensitization of muscarinic cholinergic receptors in mouse neuroblastoma cells: selective loss of agonist low-affinity and pirenzepine high-affinity binding sites. The Journal of pharmacology and experimental therapeutics, 1986, Volume: 238, Issue:3 Topics: Benzodiazepinones; Carbachol; Cells, Cultured; Cyclic GMP; N-Methylscopolamine; Neuroblastoma; Pirenzepine; Protein Conformation; Receptors, Muscarinic; Scopolamine Derivatives; Tritium	1986
Muscarinic responses and binding in a murine neuroblastoma clone (N1E-115): cyclic GMP formation is mediated by a low affinity agonist-receptor conformation and cyclic AMP reduction is mediated by a high affinity agonist-receptor conformation. Molecular pharmacology, 1986, Volume: 30, Issue:3 Topics: Animals; Benzodiazepinones; Carbachol; Cells, Cultured; Cyclic AMP; Cyclic GMP; N-Methylscopolamine; Neuroblastoma; Pirenzepine; Protein Conformation; Quinuclidinyl Benzilate; Receptors, Muscarinic; Scopolamine Derivatives	1986
Muscarinic acetylcholine receptor-mediated phosphoinositide turnover in cultured cerebellar granule cells: desensitization by receptor agonists. The Journal of pharmacology and experimental therapeutics, 1987, Volume: 242, Issue:1 Topics: Animals; Atropine; Carbachol; Cells, Cultured; Cerebellum; Kinetics; Male; N-Methylscopolamine; Oxotremorine; Phorbol Esters; Phosphatidylinositols; Pirenzepine; Quinuclidinyl Benzilate; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Scopolamine Derivatives; Virulence Factors, Bordetella	1987
Different antagonist binding properties of rat pancreatic and cardiac muscarinic receptors. Life sciences, 1987, Nov-09, Volume: 41, Issue:19 Topics: Animals; Binding, Competitive; GTP-Binding Proteins; Kinetics; Male; Myocardium; N-Methylscopolamine; Pancreas; Parasympatholytics; Piperidines; Pirenzepine; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Scopolamine Derivatives; Type C Phospholipases	1987
Pre- and post-synaptic muscarinic receptors of the rat vas deferens: an update. Puerto Rico health sciences journal, 1988, Volume: 7, Issue:2 Topics: Animals; Atropine; Binding, Competitive; Male; Membrane Potentials; Muscle, Smooth; N-Methylscopolamine; Neuromuscular Junction; Pirenzepine; Rats; Rats, Inbred Strains; Receptors, Cholinergic; Receptors, Muscarinic; Scopolamine Derivatives; Synapses; Terminology as Topic; Vas Deferens	1988
Characterization of muscarinic receptor subtypes in human tissues. Life sciences, 1988, Volume: 43, Issue:19 Topics: Brain; Cerebellum; Heart Atria; Heart Ventricles; Humans; Kinetics; Myocardium; N-Methylscopolamine; Organ Specificity; Pirenzepine; Receptors, Muscarinic; Scopolamine Derivatives; Submandibular Gland	1988
Muscarinic M1, M2 receptor binding. Relationship with functional efficacy. European journal of pharmacology, 1988, Oct-26, Volume: 156, Issue:1 Topics: Animals; Cerebral Cortex; Guanine Nucleotides; In Vitro Techniques; Intracellular Membranes; Myocardium; N-Methylscopolamine; Parasympatholytics; Pirenzepine; Rats; Receptors, Cholinergic; Receptors, Muscarinic; Scopolamine Derivatives	1988
Discriminative stimulus properties of physostigmine in rats. European journal of pharmacology, 1988, Aug-09, Volume: 153, Issue:1 Topics: Animals; Conditioning, Operant; Discrimination, Psychological; Dose-Response Relationship, Drug; Male; N-Methylscopolamine; Physostigmine; Pirenzepine; Rats; Rats, Inbred Strains; Receptors, Cholinergic; Reinforcement Schedule; Scopolamine; Scopolamine Derivatives	1988
Effects of aging on the interaction of quinuclidinyl benzilate, N-methylscopolamine, pirenzepine, and gallamine with brain muscarinic receptors. Neurochemical research, 1988, Volume: 13, Issue:12 Topics: Aging; Animals; Binding, Competitive; Cerebellum; Cerebral Cortex; Corpus Striatum; Gallamine Triethiodide; Hippocampus; In Vitro Techniques; Male; N-Methylscopolamine; Pirenzepine; Quinuclidinyl Benzilate; Radioligand Assay; Rats; Receptors, Muscarinic; Scopolamine Derivatives	1988
Does the prolonged occupancy of M1 receptors by telenzepine protect them against the action of vagally released acetylcholine? Pharmacology, 1988, Volume: 37 Suppl 1 Topics: Acetylcholine; Animals; Atropine; Binding, Competitive; Brain; Cattle; In Vitro Techniques; Kinetics; N-Methylscopolamine; Pirenzepine; Rats; Receptors, Muscarinic; Scopolamine Derivatives; Vagus Nerve	1988
Characterization of cholinergic muscarinic receptors in the rabbit iris. Biochemical pharmacology, 1988, Jul-01, Volume: 37, Issue:13 Topics: Animals; Atropine; Carbachol; Cerebral Cortex; Ileum; Iris; Kinetics; Methacholine Chloride; Methacholine Compounds; Microsomes; N-Methylscopolamine; Oxotremorine; Pirenzepine; Quinuclidinyl Benzilate; Rabbits; Receptors, Muscarinic; Scopolamine Derivatives	1988
Pressor and intestinal vascular bed responses to vasopressin after cholinergic blockade. The American journal of physiology, 1988, Volume: 254, Issue:1 Pt 2 Topics: Animals; Arginine Vasopressin; Blood Pressure; Cats; Dose-Response Relationship, Drug; Electric Conductivity; Heart Rate; Intestines; N-Methylscopolamine; Pirenzepine; Regional Blood Flow; Scopolamine Derivatives; Splanchnic Circulation; Vasopressins	1988
Muscarinic cholinergic receptor subtypes in hippocampus in human cognitive disorders. Journal of neurochemistry, 1988, Volume: 50, Issue:3 Topics: Acetylcholinesterase; Aging; Choline O-Acetyltransferase; Cognition Disorders; Hippocampus; Humans; N-Methylscopolamine; Parasympatholytics; Parkinson Disease; Pirenzepine; Receptors, Muscarinic; Reference Values; Scopolamine Derivatives	1988
Autoradiographic localization and biochemical characteristics of M1 and M2 muscarinic binding sites in the striatum of the cat, monkey, and human. The Journal of neuroscience : the official journal of the Society for Neuroscience, 1988, Volume: 8, Issue:3 Topics: Animals; Autoradiography; Binding Sites; Cats; Corpus Striatum; Dopamine; Humans; Macaca fascicularis; N-Methylscopolamine; Pirenzepine; Receptors, Muscarinic; Scopolamine Derivatives	1988
Muscarinic stimulation of submucosal glands in swine trachea. Journal of applied physiology (Bethesda, Md. : 1985), 1988, Volume: 64, Issue:1 Topics: Animals; Atropine; Binding, Competitive; Carbachol; Exocrine Glands; Isoflurophate; Male; Mucus; N-Methylscopolamine; Pirenzepine; Quinuclidinyl Benzilate; Receptors, Muscarinic; Scopolamine Derivatives; Swine; Trachea	1988
Characterization of muscarinic receptors in guinea pig ileum longitudinal smooth muscle. Molecular pharmacology, 1988, Volume: 33, Issue:6 Topics: Animals; Binding, Competitive; Guinea Pigs; Ileum; In Vitro Techniques; Kinetics; Male; Muscle, Smooth; Myocardium; N-Methylscopolamine; Parasympatholytics; Phenoxybenzamine; Piperidines; Pirenzepine; Receptors, Muscarinic; Salivary Glands; Scopolamine Derivatives	1988
Selective antagonism by pirenzepine and N-methyl-scopolamine on muscarinic receptor subtypes of the rat vas deferens. General pharmacology, 1988, Volume: 19, Issue:3 Topics: Animals; Male; Muscle Contraction; Muscle, Smooth; N-Methylscopolamine; Parasympatholytics; Pirenzepine; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Scopolamine Derivatives; Vas Deferens	1988
Direct binding studies on ileal and cardiac muscarinic receptors. British journal of pharmacology, 1987, Volume: 92, Issue:4 Topics: Animals; Gallamine Triethiodide; Guinea Pigs; Ileum; In Vitro Techniques; Kinetics; Male; Membranes; Muscle, Smooth; Myocardium; N-Methylscopolamine; Pirenzepine; Receptors, Muscarinic; Scopolamine Derivatives	1987
Characterization of the muscarinic receptor subtype in isolated gastric fundic cells of the rabbit. Biochemical pharmacology, 1987, Sep-15, Volume: 36, Issue:18 Topics: Aminopyrine; Animals; Atropine; Carbachol; Gastric Fundus; Kinetics; Male; N-Methylscopolamine; Piperidines; Pirenzepine; Rabbits; Receptors, Muscarinic; Scopolamine Derivatives	1987
Characterization of muscarinic receptors in salivary and lacrimal glands of the rat. European journal of pharmacology, 1987, Nov-10, Volume: 143, Issue:2 Topics: Animals; Atropine Derivatives; Dicyclomine; Exocrine Glands; In Vitro Techniques; Lacrimal Apparatus; Male; N-Methylscopolamine; Pirenzepine; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Salivary Glands; Scopolamine Derivatives; Synaptosomes	1987
Muscarinic receptor binding and muscarinic receptor-mediated inhibition of adenylate cyclase in rat brain myelin. The Journal of neuroscience : the official journal of the Society for Neuroscience, 1987, Volume: 7, Issue:12 Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Brain Stem; Myelin Sheath; N-Methylscopolamine; Parasympatholytics; Pirenzepine; Quinuclidinyl Benzilate; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Scopolamine Derivatives; Tritium	1987
Intestinal permeation of nonquaternary amines: a study with telenzepine and pirenzepine in the isolated mucosa of guinea pig jejunum and colon. The Journal of pharmacology and experimental therapeutics, 1987, Volume: 243, Issue:3 Topics: Animals; Biological Transport; Colon; Dose-Response Relationship, Drug; Guinea Pigs; Hydrogen-Ion Concentration; In Vitro Techniques; Intestinal Mucosa; Jejunum; N-Methylscopolamine; Permeability; Phenoxybenzamine; Pirenzepine; Polyethylene Glycols; Scopolamine Derivatives; Temperature	1987
Autoradiographic localization of muscarinic cholinergic receptors in visual areas of cat brain: variations in sensitivity of N-[3H]methylscopolamine binding sites to carbachol and pirenzepine. Neuroscience letters, 1987, Oct-16, Volume: 81, Issue:1-2 Topics: Animals; Autoradiography; Brain; Carbachol; Cats; Male; N-Methylscopolamine; Pirenzepine; Receptors, Muscarinic; Scopolamine Derivatives; Tritium; Visual Pathways	1987
Muscarinic cholinergic receptor subtypes in the human brain. II. Quantitative autoradiographic studies. Brain research, 1986, Jan-08, Volume: 362, Issue:2 Topics: Aged; Autoradiography; Benzodiazepinones; Binding Sites; Binding, Competitive; Brain; Classification; Female; Humans; Male; N-Methylscopolamine; Pirenzepine; Receptors, Muscarinic; Scopolamine Derivatives; Tissue Distribution; Tritium	1986
Parallel postnatal development of choline acetyltransferase activity and muscarinic acetylcholine receptors in the rat olfactory bulb. Journal of neurochemistry, 1986, Volume: 46, Issue:3 Topics: Animals; Animals, Newborn; Benzodiazepinones; Binding, Competitive; Choline O-Acetyltransferase; Electrophoresis, Polyacrylamide Gel; Guanylyl Imidodiphosphate; Isoelectric Point; Molecular Weight; N-Methylscopolamine; Olfactory Bulb; Pirenzepine; Propylbenzilylcholine Mustard; Quinuclidinyl Benzilate; Radioligand Assay; Rats; Receptors, Muscarinic; Receptors, Nicotinic; Scopolamine Derivatives	1986
The binding of pirenzepine to digitonin-solubilized muscarinic acetylcholine receptors from the rat myocardium. British journal of pharmacology, 1986, Volume: 87, Issue:2 Topics: Animals; Benzodiazepinones; Binding, Competitive; Cell Membrane; Centrifugation, Density Gradient; Digitonin; In Vitro Techniques; Myocardium; N-Methylscopolamine; Oxotremorine; Pirenzepine; Rats; Receptors, Muscarinic; Scopolamine Derivatives; Solubility	1986
Binding profile of a novel cardioselective muscarine receptor antagonist, AF-DX 116, to membranes of peripheral tissues and brain in the rat. Life sciences, 1986, May-05, Volume: 38, Issue:18 Topics: Animals; Benzodiazepinones; Binding, Competitive; Cell Membrane; Cerebellum; Cerebral Cortex; Kinetics; Lacrimal Apparatus; Male; Myocardium; N-Methylscopolamine; Organ Specificity; Parasympatholytics; Pirenzepine; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Scopolamine Derivatives; Submandibular Gland	1986
In vitro effects of gallamine on dissociation kinetics of (3H)N-methylscopolamine and (3H)pirenzepine from rat brain muscarinic receptors. Journal of receptor research, 1986, Volume: 6, Issue:1 Topics: Animals; Atropine; Benzodiazepinones; Binding, Competitive; Cerebral Cortex; Corpus Striatum; Gallamine Triethiodide; Hippocampus; Kinetics; Male; Myocardium; N-Methylscopolamine; Pirenzepine; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Scopolamine Derivatives; Substrate Specificity	1986
Multiple binding affinities of N-methylscopolamine to brain muscarinic acetylcholine receptors: differentiation from M1 and M2 receptor subtypes. The Journal of pharmacology and experimental therapeutics, 1986, Volume: 238, Issue:2 Topics: Animals; Benzodiazepinones; Binding, Competitive; Brain; Hot Temperature; In Vitro Techniques; Male; N-Methylscopolamine; Phospholipases A; Phospholipases A2; Pirenzepine; Quinuclidinyl Benzilate; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Scopolamine Derivatives; Trypsin	1986
A selective effect of protein kinase C activation on pirenzepine high-affinity muscarinic receptors in a neuronal clone. European journal of pharmacology, 1986, Sep-23, Volume: 129, Issue:1-2 Topics: Binding, Competitive; Clone Cells; Enzyme Activation; N-Methylscopolamine; Neurons; Pirenzepine; Protein Kinase C; Receptors, Muscarinic; Scopolamine Derivatives; Tetradecanoylphorbol Acetate	1986
Effects of aging and cholinergic deafferentation on putative muscarinic cholinergic receptor subtypes in rat cerebral cortex. Neuroscience letters, 1986, Oct-08, Volume: 70, Issue:2 Topics: Acetylcholine; Aging; Animals; Binding, Competitive; Cerebral Cortex; Choline O-Acetyltransferase; Denervation; Male; N-Methylscopolamine; Olivary Nucleus; Pirenzepine; Quinuclidinyl Benzilate; Rats; Rats, Inbred F344; Receptors, Cholinergic; Scopolamine Derivatives	1986
Selective labelling of M1-receptors in autonomic ganglia with 3H-pirenzepine. Arzneimittel-Forschung, 1985, Volume: 35, Issue:1A Topics: Animals; Atropine; Benzodiazepinones; Binding, Competitive; Cattle; Ganglia, Autonomic; Ganglia, Sympathetic; In Vitro Techniques; N-Methylscopolamine; Pirenzepine; Quinuclidinyl Benzilate; Radioligand Assay; Receptors, Muscarinic; Scopolamine Derivatives; Synaptosomes	1985
Muscarinic acetylcholine receptors in chick heart: influence of heat and N-ethylmaleimide on receptor conformations and interactions with guanine nucleotide-dependent regulatory proteins. Neuroscience letters, 1985, Mar-15, Volume: 54, Issue:2-3 Topics: Animals; Benzodiazepinones; Carbachol; Chick Embryo; Ethylmaleimide; Heart; Hot Temperature; Molecular Conformation; Myocardium; N-Methylscopolamine; Pirenzepine; Receptors, Muscarinic; Scopolamine Derivatives	1985
Heterogeneity of binding of muscarinic receptor antagonists in rat brain homogenates. The Journal of pharmacology and experimental therapeutics, 1985, Volume: 233, Issue:3 Topics: Animals; Benzodiazepinones; Binding Sites; Brain; Female; In Vitro Techniques; Male; N-Methylscopolamine; Parasympatholytics; Pirenzepine; Quinuclidinyl Benzilate; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Scopolamine Derivatives; Tritium	1985
Muscarinic receptors in isolated gastric fundic mucosal cells. Binding-activity relationships. Biochemical pharmacology, 1985, Jul-01, Volume: 34, Issue:13 Topics: Aminopyrine; Animals; Benzodiazepinones; Binding Sites; Carbon Radioisotopes; Gastric Fundus; Gastric Mucosa; In Vitro Techniques; N-Methylscopolamine; Pirenzepine; Rabbits; Receptors, Muscarinic; Scopolamine Derivatives; Time Factors; Tritium	1985
The binding of a 2-chloroethylamine derivative of oxotremorine (BM 123) to muscarinic receptors in the rat cerebral cortex. Molecular pharmacology, 1985, Volume: 28, Issue:2 Topics: Alkylation; Animals; Atropine; Benzodiazepinones; Binding Sites; Binding, Competitive; Cerebral Cortex; Gallamine Triethiodide; Kinetics; N-Methylscopolamine; Oxotremorine; Pirenzepine; Pyrrolidinones; Quinuclidinyl Benzilate; Rats; Receptors, Muscarinic; Scopolamine Derivatives; Structure-Activity Relationship; Thiosulfates	1985
Cortical muscarinic receptor subtypes and Alzheimer's disease. Lancet (London, England), 1982, Dec-04, Volume: 2, Issue:8310 Topics: Alzheimer Disease; Benzodiazepinones; Binding, Competitive; Cerebral Cortex; Dementia; Humans; N-Methylscopolamine; Parasympatholytics; Pirenzepine; Receptors, Cholinergic; Receptors, Muscarinic; Scopolamine Derivatives	1982
Muscarinic cholinergic receptors in a rat phaeochromocytoma cell line. Biochemical and biophysical research communications, 1984, Feb-29, Volume: 119, Issue:1 Topics: Animals; Benzodiazepinones; Cell Line; N-Methylscopolamine; Pheochromocytoma; Pirenzepine; Rats; Receptors, Muscarinic; Scopolamine Derivatives	1984
Comparative studies of the effects of some antimuscarinic agents on gastric damage and pupillary reflex in the rat. British journal of pharmacology, 1984, Volume: 82, Issue:2 Topics: Animals; Atropine; Benzodiazepinones; Female; N-Methylscopolamine; Oxotremorine; Parasympatholytics; Pirenzepine; Propantheline; Rats; Rats, Inbred Strains; Reflex, Pupillary; Scopolamine Derivatives; Stomach Diseases	1984
Pharmacological evidence for cardiac muscarinic receptor subtypes. Life sciences, 1984, Oct-22, Volume: 35, Issue:17 Topics: Acetylcholine; Animals; Arecoline; Atropine; Benzodiazepinones; Binding Sites; Butylscopolammonium Bromide; Carbachol; Female; Guinea Pigs; Heart Rate; Male; Myocardial Contraction; Myocardium; N-Methylscopolamine; Pirenzepine; Quaternary Ammonium Compounds; Receptors, Muscarinic; Scopolamine Derivatives	1984
Subclasses of muscarinic receptors in isolated gastric mucosal cells: receptor characterization and parietal cell function. European journal of pharmacology, 1983, Oct-28, Volume: 94, Issue:3-4 Topics: Animals; Atropine; Benzodiazepinones; Binding, Competitive; Carbachol; Dogs; Gastric Mucosa; Guanine Nucleotides; Guinea Pigs; In Vitro Techniques; Male; Models, Biological; N-Methylscopolamine; Pilocarpine; Pirenzepine; Receptors, Muscarinic; Scopolamine Derivatives	1983
The binding properties of the muscarinic receptors of the cynomolgus monkey ciliary body and the response to the induction of agonist subsensitivity. British journal of pharmacology, 1982, Volume: 77, Issue:4 Topics: Animals; Benzodiazepinones; Carbachol; Ciliary Body; Guanylyl Imidodiphosphate; Kinetics; Macaca fascicularis; N-Methylscopolamine; Pilocarpine; Pirenzepine; Receptors, Cholinergic; Receptors, Muscarinic; Scopolamine Derivatives	1982
Muscarinic receptors in the stomach. Scandinavian journal of gastroenterology. Supplement, 1980, Volume: 66 Topics: Animals; Benzodiazepinones; Carbachol; Dogs; Gastric Fundus; Gastric Mucosa; Guanosine Triphosphate; Muscarinic Antagonists; Muscle, Smooth; N-Methylscopolamine; Piperazines; Pirenzepine; Receptors, Cholinergic; Receptors, Muscarinic; Scopolamine Derivatives; Sympathetic Nervous System	1980
Subclasses of muscarinic receptors and pirenzepine. Further experimental evidence. Scandinavian journal of gastroenterology. Supplement, 1982, Volume: 72 Topics: Atropine; Benzodiazepinones; Gastric Juice; Humans; N-Methylscopolamine; Pirenzepine; Receptors, Cholinergic; Receptors, Muscarinic; Scopolamine Derivatives	1982
Muscarinic toxins from the venom of Dendroaspis snakes with agonist-like actions. Toxicon : official journal of the International Society on Toxinology, 1995, Volume: 33, Issue:4 Topics: Animals; Behavior, Animal; Cerebral Cortex; Elapid Venoms; In Vitro Techniques; Kinetics; Ligands; Memory; Muscarinic Agonists; N-Methylscopolamine; Pirenzepine; Rats; Rats, Wistar; Receptors, Cholinergic; Scopolamine Derivatives; Species Specificity; Stereotaxic Techniques; Synaptosomes	1995
Functional expression of a cloned Drosophila muscarinic acetylcholine receptor in a stable Drosophila cell line. The Journal of experimental biology, 1995, Volume: 198, Issue:Pt 9 Topics: Animals; Calcium; Cell Line; Cloning, Molecular; Drosophila melanogaster; Electrophoresis, Polyacrylamide Gel; Fluorescent Dyes; Fura-2; Gene Expression Regulation; Microscopy, Fluorescence; Molecular Weight; N-Methylscopolamine; Parasympatholytics; Pirenzepine; Receptors, Muscarinic; Scopolamine Derivatives	1995
Muscarinic receptor subtypes are differentially distributed across brain stem respiratory nuclei. The American journal of physiology, 1995, Volume: 268, Issue:6 Pt 1 Topics: Animals; Autoradiography; Brain Stem; Cats; Medulla Oblongata; N-Methylscopolamine; Organ Specificity; Parasympatholytics; Pirenzepine; Pons; Radioligand Assay; Receptors, Muscarinic; Respiration; Scopolamine Derivatives; Solitary Nucleus; Tritium	1995
Cooperativity manifest in the binding properties of purified cardiac muscarinic receptors. The Journal of biological chemistry, 1995, Sep-22, Volume: 270, Issue:38 Topics: Allosteric Regulation; Animals; GTP-Binding Proteins; Guanylyl Imidodiphosphate; In Vitro Techniques; Molecular Weight; Muscarinic Antagonists; Myocardium; N-Methylscopolamine; Oxotremorine; Parasympatholytics; Pirenzepine; Quinuclidinyl Benzilate; Radioligand Assay; Receptors, Muscarinic; Sarcolemma; Scopolamine Derivatives; Swine	1995
Atropine and glycopyrronium show similar binding patterns to M2 (cardiac) and M3 (submandibular gland) muscarinic receptor subtypes in the rat. British journal of anaesthesia, 1995, Volume: 74, Issue:5 Topics: Animals; Atropine; Binding, Competitive; Glycopyrrolate; Heart Ventricles; In Vitro Techniques; Male; N-Methylscopolamine; Parasympatholytics; Pirenzepine; Rats; Rats, Wistar; Receptors, Muscarinic; Scopolamine Derivatives; Submandibular Gland	1995
Localization of muscarinic receptor subtypes in brain stem areas regulating sleep. Neuroreport, 1994, Aug-15, Volume: 5, Issue:13 Topics: Animals; Autoradiography; Brain Stem; Cats; N-Methylscopolamine; Parasympatholytics; Pirenzepine; Receptors, Muscarinic; Scopolamine Derivatives; Sleep, REM	1994
Two populations of muscarinic binding sites in the chick heart distinguished by affinities for ligands and selective inactivation. British journal of pharmacology, 1994, Volume: 113, Issue:4 Topics: Alcuronium; Animals; Chickens; Choline; Cholinergic Agents; Diamines; Female; In Vitro Techniques; Ligands; Male; Muscarinic Antagonists; Myocardium; N-Methylscopolamine; Parasympatholytics; Pirenzepine; Radioligand Assay; Rats; Rats, Wistar; Receptors, Muscarinic; RNA, Messenger; Scopolamine Derivatives	1994
Pertussis toxin blocks M2 muscarinic receptor-mediated effects on contraction and cyclic AMP in the guinea pig ileum, but not M3-mediated contractions and phosphoinositide hydrolysis. The Journal of pharmacology and experimental therapeutics, 1994, Volume: 271, Issue:2 Topics: Adenosine Diphosphate Ribose; Adenylate Cyclase Toxin; Animals; Cyclic AMP; Guanosine Triphosphate; Guinea Pigs; Hydrolysis; Ileum; In Vitro Techniques; Isoproterenol; Male; Muscle Contraction; N-Methylscopolamine; Pertussis Toxin; Phosphatidylinositols; Pirenzepine; Receptors, Muscarinic; Scopolamine Derivatives; Signal Transduction; Virulence Factors, Bordetella	1994
Binding and functional properties of hexocyclium and sila-hexocyclium derivatives to muscarinic receptor subtypes. British journal of pharmacology, 1994, Volume: 112, Issue:2 Topics: Animals; Cattle; Female; Guinea Pigs; Humans; In Vitro Techniques; Male; N-Methylscopolamine; Parasympatholytics; Piperazines; Pirenzepine; Rabbits; Radioligand Assay; Rats; Rats, Wistar; Receptors, Muscarinic; Scopolamine Derivatives; Structure-Activity Relationship; Tumor Cells, Cultured; Vas Deferens	1994
Protein toxins that bind to muscarinic acetylcholine receptors. Annals of the New York Academy of Sciences, 1994, Mar-09, Volume: 710 Topics: Amino Acid Sequence; Animals; Binding, Competitive; Brain; Consensus Sequence; Elapid Venoms; Elapidae; Guinea Pigs; Ileum; In Vitro Techniques; Kinetics; Molecular Sequence Data; Muscle Contraction; Muscle, Smooth; N-Methylscopolamine; Parasympatholytics; Pirenzepine; Protein Binding; Radioligand Assay; Receptors, Muscarinic; Scopolamine Derivatives; Sequence Homology, Amino Acid; Swine; Synaptosomes	1994
Pharmacological characterization of muscarinic receptors in neonatal rat cardiomyocytes. The American journal of physiology, 1993, Volume: 265, Issue:3 Pt 1 Topics: Animals; Animals, Newborn; Cells, Cultured; Cyclic AMP; Inositol Phosphates; Kinetics; Muscarine; Muscarinic Antagonists; Myocardium; N-Methylscopolamine; Piperidines; Pirenzepine; Rats; Receptors, Muscarinic; Scopolamine Derivatives	1993
Characterization of muscarinic receptors on guinea pig gallbladder smooth muscle. Gastroenterology, 1993, Volume: 105, Issue:5 Topics: Animals; Autoradiography; Carbachol; Gallbladder; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; N-Methylscopolamine; Pirenzepine; Receptors, Muscarinic; Scopolamine Derivatives; Tetrodotoxin	1993
The synthesis and biochemical pharmacology of enantiomerically pure methylated oxotremorine derivatives. Journal of medicinal chemistry, 1993, Nov-12, Volume: 36, Issue:23 Topics: Animals; Binding, Competitive; Cerebral Cortex; Guanylyl Imidodiphosphate; Male; Methylation; N-Methylscopolamine; Oxotremorine; Pirenzepine; Quinuclidinyl Benzilate; Rats; Rats, Wistar; Receptors, Muscarinic; Scopolamine Derivatives; Stereoisomerism	1993
Studies of muscarinic receptor reserve linked to phosphoinositide hydrolysis in parotid gland and cerebral cortex. Acta physiologica Scandinavica, 1993, Volume: 147, Issue:3 Topics: Animals; Carbachol; Cerebral Cortex; Choline; Guinea Pigs; Hydrolysis; In Vitro Techniques; Kinetics; N-Methylscopolamine; Oxotremorine; Parasympathomimetics; Parotid Gland; Phosphatidylinositols; Pirenzepine; Receptors, Muscarinic; Scopolamine Derivatives	1993
Synthesis and muscarinic receptor binding profiles of antagonist benzotriazole derivatives. Farmaco (Societa chimica italiana : 1989), 1993, Volume: 48, Issue:7 Topics: Animals; Chromatography, Thin Layer; Guinea Pigs; Ileum; In Vitro Techniques; Kinetics; Male; Muscarinic Antagonists; N-Methylscopolamine; Parasympatholytics; Pirenzepine; Rabbits; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Scopolamine Derivatives; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet; Triazoles	1993
Muscarinic M3 receptors mediate total inositol phosphates accumulation in murine HSDM1C1 fibrosarcoma cells. European journal of pharmacology, 1993, Jan-04, Volume: 244, Issue:1 Topics: Animals; Binding, Competitive; Carbachol; Dioxolanes; Fibrosarcoma; Inositol Phosphates; Mice; Muscarine; Muscarinic Antagonists; N-Methylscopolamine; Oxotremorine; Parasympatholytics; Parasympathomimetics; Pirenzepine; Radioligand Assay; Receptors, Muscarinic; Scopolamine Derivatives; Tumor Cells, Cultured	1993
Differences between rat dorsal and ventral hippocampus in muscarinic receptor agonist binding and interaction with phospholipase C. European journal of pharmacology, 1993, Jan-15, Volume: 244, Issue:2 Topics: Alkaloids; Animals; Carbachol; Furans; Guanylyl Imidodiphosphate; Hippocampus; Male; Membranes; Mitochondria; N-Methylscopolamine; Naphthalenes; Oxotremorine; Parasympatholytics; Parasympathomimetics; Phosphatidylinositols; Piperidines; Pirenzepine; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Scopolamine Derivatives; Synaptosomes; Type C Phospholipases	1993
Constitutive activity of the M1-M4 subtypes of muscarinic receptors in transfected CHO cells and of muscarinic receptors in the heart cells revealed by negative antagonists. FEBS letters, 1995, Dec-18, Volume: 377, Issue:2 Topics: Animals; Atropine; Carbachol; Cells, Cultured; CHO Cells; Cricetinae; Cyclic AMP; Humans; Inositol Phosphates; Muscarinic Antagonists; Myocardium; N-Methylscopolamine; Pirenzepine; Quinuclidinyl Benzilate; Rats; Receptors, Muscarinic; Scopolamine Derivatives; Transfection; Tritium	1995
Muscarinic cholinergic receptors in brain and atrial membranes of adult brook trout (Salvelinus fontinalis) measured by radioligand binding techniques. Comparative biochemistry and physiology. Part C, Pharmacology, toxicology & endocrinology, 1995, Volume: 112, Issue:1 Topics: Animals; Atropine; Binding, Competitive; Brain Chemistry; Carbachol; Heart Atria; Kinetics; Muscarinic Agonists; Muscarinic Antagonists; N-Methylscopolamine; Oxotremorine; Parasympatholytics; Pirenzepine; Radioligand Assay; Receptors, Muscarinic; Scopolamine; Scopolamine Derivatives; Trout	1995
Stereoselective inhibition of muscarinic receptor subtypes by the eight stereoisomers related to rociverine. European journal of pharmacology, 1995, Jul-18, Volume: 290, Issue:2 Topics: Animals; CHO Cells; Cricetinae; Cyclohexanecarboxylic Acids; Female; Muscarinic Antagonists; N-Methylscopolamine; Parasympatholytics; Pirenzepine; Receptors, Muscarinic; Scopolamine Derivatives; Structure-Activity Relationship; Transfection	1995
Characterization of muscarinic acetylcholine receptors in cultured adult skin fibroblasts: effects of the Swedish Alzheimer's disease APP 670/671 mutation on binding levels. Journal of neural transmission. Parkinson's disease and dementia section, 1995, Volume: 10, Issue:1 Topics: Aged; Alzheimer Disease; Amyloid beta-Protein Precursor; Cells, Cultured; Fibroblasts; Humans; Mutation; N-Methylscopolamine; Parasympatholytics; Pirenzepine; Quinuclidinyl Benzilate; Receptors, Muscarinic; Reference Values; Scopolamine Derivatives; Skin; Sweden	1995
Changes in rat brain muscarinic receptors after inhibitory avoidance learning. Life sciences, 1996, Volume: 58, Issue:9 Topics: Amygdala; Animals; Avoidance Learning; Brain; Cerebral Cortex; Discrimination, Psychological; Hippocampus; Kinetics; Male; Memory; N-Methylscopolamine; Neostriatum; Organ Specificity; Oxotremorine; Pirenzepine; Rats; Rats, Wistar; Receptors, Muscarinic; Reinforcement, Psychology; Scopolamine Derivatives	1996
Location and quantification of muscarinic receptor subtypes in rat pons: implications for REM sleep generation. The American journal of physiology, 1997, Volume: 273, Issue:3 Pt 2 Topics: Animals; Autoradiography; Brain Mapping; Brain Stem; Locus Coeruleus; Male; N-Methylscopolamine; Pirenzepine; Pons; Propionates; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Receptor, Muscarinic M1; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Receptors, Muscarinic; Reticular Formation; Scopolamine Derivatives; Sleep, REM; Trigeminal Nuclei; Tritium	1997
Use of antimuscarinic toxins to facilitate studies of striatal m4 muscarinic receptors. The Journal of pharmacology and experimental therapeutics, 1998, Volume: 284, Issue:2 Topics: Alkaloids; Animals; Benzodiazepines; Binding, Competitive; Cats; CHO Cells; Corpus Striatum; Cricetinae; Elapid Venoms; Furans; Gallamine Triethiodide; Humans; Male; Muscarinic Antagonists; N-Methylscopolamine; Naphthalenes; Neurotoxins; Piperidines; Pirenzepine; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptor, Muscarinic M1; Receptor, Muscarinic M4; Receptors, Muscarinic; Recombinant Proteins	1998
Pharmacological analysis of the novel mode of interaction between xanomeline and the M1 muscarinic acetylcholine receptor. The Journal of pharmacology and experimental therapeutics, 1999, Volume: 289, Issue:3 Topics: Animals; Atropine; Binding, Competitive; Carbachol; CHO Cells; Citrulline; Cricetinae; Humans; Kinetics; Muscarinic Agonists; N-Methylscopolamine; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Pirenzepine; Pyridines; Radioligand Assay; Receptor, Muscarinic M1; Receptors, Muscarinic; Recombinant Proteins; Thiadiazoles; Transfection; Tritium	1999
Impaired atrial M(2)-cholinoceptor function in obesity-related hypertension. Hypertension (Dallas, Tex. : 1979), 1999, Volume: 34, Issue:5 Topics: Adenylyl Cyclases; Animals; Blood Pressure; Body Weight; Dogs; Dose-Response Relationship, Drug; Heart Atria; Hypertension; Male; N-Methylscopolamine; Obesity; Pirenzepine; Receptor, Muscarinic M2; Receptors, Muscarinic	1999
Quinolizidinyl derivatives of 5,11-dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one as ligands for muscarinic receptors. Bioorganic & medicinal chemistry letters, 1999, Oct-18, Volume: 9, Issue:20 Topics: Animals; Benzodiazepinones; Binding, Competitive; Ligands; N-Methylscopolamine; Pirenzepine; Pyridines; Quinolizines; Radioligand Assay; Rats; Receptors, Muscarinic	1999
Decreased binding affinity of olanzapine and clozapine for human muscarinic receptors in intact clonal cells in physiological medium. European journal of pharmacology, 2000, Mar-03, Volume: 390, Issue:3 Topics: Animals; Benzodiazepines; Binding, Competitive; CHO Cells; Clozapine; Cricetinae; Dose-Response Relationship, Drug; Humans; Hypotonic Solutions; Isotonic Solutions; Membranes; N-Methylscopolamine; Olanzapine; Pirenzepine; Radioligand Assay; Receptors, Muscarinic; Tritium	2000
Syntheses of R and S isomers of AF-DX 384, a selective antagonist of muscarinic M2 receptors. Bioorganic & medicinal chemistry, 2000, Volume: 8, Issue:3 Topics: Animals; Binding, Competitive; Cyclodextrins; Electrophoresis, Capillary; Ligands; Magnetic Resonance Spectroscopy; Molecular Structure; Muscarinic Antagonists; Myocardium; N-Methylscopolamine; Parasympatholytics; Pirenzepine; Rats; Solvents; Stereoisomerism; Tritium	2000
Functional role of muscarinic M(2) receptors in alpha,beta-methylene ATP induced, neurogenic contractions in guinea-pig ileum. British journal of pharmacology, 2000, Volume: 129, Issue:7 Topics: Adenosine Triphosphate; Animals; Diphenylacetic Acids; Dose-Response Relationship, Drug; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscarinic Antagonists; Muscle Contraction; N-Methylscopolamine; Pertussis Toxin; Piperidines; Pirenzepine; Receptor, Muscarinic M2; Receptors, Muscarinic; Tetrodotoxin; Virulence Factors, Bordetella	2000
The allosteric interaction of otenzepad (AF-DX 116) at muscarinic M2 receptors in guinea pig atria. European journal of pharmacology, 2001, Mar-30, Volume: 416, Issue:3 Topics: Acetylcholine; Allosteric Regulation; Animals; Atropine; Carbachol; Cardiotonic Agents; Dexetimide; Electric Stimulation; Female; Gallamine Triethiodide; Guinea Pigs; Heart Atria; In Vitro Techniques; Kinetics; Male; Muscarinic Antagonists; N-Methylscopolamine; Nicotinic Antagonists; Parasympatholytics; Phthalimides; Pirenzepine; Quaternary Ammonium Compounds; Radioligand Assay; Receptor, Muscarinic M2; Receptors, Muscarinic	2001
Comparison of the pharmacological antagonism of M2 and M3 muscarinic receptors expressed in isolation and in combination. Biochemical pharmacology, 2003, Apr-15, Volume: 65, Issue:8 Topics: Animals; CHO Cells; Cricetinae; Cyclic AMP; Humans; Kinetics; Muscarinic Antagonists; N-Methylscopolamine; Oxotremorine; Phosphatidylinositols; Pirenzepine; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Receptors, Muscarinic; Recombinant Proteins; Transfection	2003
M1 muscarinic receptors contribute to, whereas M4 receptors inhibit, dopamine D1 receptor-induced [3H]-cyclic AMP accumulation in rat striatal slices. Neurochemical research, 2006, Volume: 31, Issue:4 Topics: Alkaloids; Animals; Benzazepines; Carbachol; Cholinergic Agonists; Corpus Striatum; Cyclic AMP; Dopamine Agonists; Furans; Male; Muscarinic Antagonists; N-Methylscopolamine; Naphthalenes; Parasympatholytics; Piperidines; Pirenzepine; Protein Kinase C; Radioligand Assay; Rats; Rats, Wistar; Receptor, Muscarinic M1; Receptor, Muscarinic M4; Receptors, Dopamine D1	2006
Nucleus accumbens acetylcholine and food intake: decreased muscarinic tone reduces feeding but not food-seeking. Behavioural brain research, 2009, Mar-02, Volume: 198, Issue:1 Topics: Acetylcholine; Animals; Dose-Response Relationship, Drug; Eating; Feeding Behavior; Male; Microinjections; Muscarinic Agonists; Muscarinic Antagonists; N-Methylscopolamine; Nucleus Accumbens; Oxotremorine; Parasympatholytics; Pirenzepine; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic	2009
Detection of novel functional selectivity at M3 muscarinic acetylcholine receptors using a Saccharomyces cerevisiae platform. ACS chemical biology, 2010, Apr-16, Volume: 5, Issue:4 Topics: 3T3 Cells; Animals; Atropine; Gene Expression; Genes, Reporter; GTP-Binding Protein alpha Subunits; GTP-Binding Protein alpha Subunits, Gq-G11; Humans; Mice; Muscarinic Antagonists; N-Methylscopolamine; Pirenzepine; Receptor, Muscarinic M3; Recombinant Fusion Proteins; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins	2010
Loss of muscarinic and purinergic receptors in urinary bladder of rats with hydrochloric acid-induced cystitis. Urology, 2010, Volume: 76, Issue:4 Topics: Adenosine Triphosphate; Animals; Benzhydryl Compounds; Benzofurans; Cresols; Cystitis; Disease Models, Animal; Down-Regulation; Female; Hydrochloric Acid; Mandelic Acids; N-Methylscopolamine; Organophosphonates; Phenols; Phenylpropanolamine; Pirenzepine; Polycyclic Compounds; Pyridoxal Phosphate; Pyrrolidines; Quinuclidines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Receptors, Purinergic; Solifenacin Succinate; Tetrahydroisoquinolines; Tolterodine Tartrate; Urinary Bladder; Urination; Urodynamics	2010
Intracellular distribution of functional M(1) -muscarinic acetylcholine receptors in N1E-115 neuroblastoma cells. Journal of neurochemistry, 2011, Volume: 118, Issue:6 Topics: Animals; Atropine; Blotting, Western; Calcium; Carbachol; Cell Line, Tumor; Elapid Venoms; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Immunohistochemistry; Inositol Phosphates; Kinetics; Mice; Muscarinic Agonists; Muscarinic Antagonists; N-Methylscopolamine; Neuroblastoma; Peptides, Cyclic; Pirenzepine; Protein Kinase Inhibitors; Quinuclidinyl Benzilate; Receptor, Muscarinic M1; Receptors, Cell Surface	2011
Comparison of subcellular distribution and functions between exogenous and endogenous M1 muscarinic acetylcholine receptors. Life sciences, 2013, Jul-19, Volume: 93, Issue:1 Topics: Analysis of Variance; Animals; Atropine; Blotting, Western; Calcium; CHO Cells; Cricetinae; Cricetulus; Mice; Microscopy, Confocal; N-Methylscopolamine; Organelles; Pirenzepine; Quinuclidinyl Benzilate; Radioligand Assay; Receptor, Muscarinic M1; Recombinant Proteins; Tritium	2013
Changes in BQCA Allosteric Modulation of [(3)H]NMS Binding to Human Cortex within Schizophrenia and by Divalent Cations. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2016, Volume: 41, Issue:6 Topics: Allosteric Regulation; Cations, Divalent; Cerebral Cortex; Female; Humans; Male; Middle Aged; N-Methylscopolamine; Pirenzepine; Quinolines; Receptor, Muscarinic M1; Receptors, Muscarinic; Schizophrenia	2016
Structural insights into the subtype-selective antagonist binding to the M Nature chemical biology, 2018, Volume: 14, Issue:12 Topics: Binding Sites; Crystallography, X-Ray; Enzyme Stability; Humans; Molecular Dynamics Simulation; Muscarinic Antagonists; Mutation; N-Methylscopolamine; Pirenzepine; Receptor, Muscarinic M2	2018