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n-methylscopolamine and oxotremorine

n-methylscopolamine has been researched along with oxotremorine in 94 studies

Research

Studies (94)

Timeframe	Studies, this research(%)	All Research%
pre-1990	42 (44.68)	18.7374
1990's	41 (43.62)	18.2507
2000's	9 (9.57)	29.6817
2010's	1 (1.06)	24.3611
2020's	1 (1.06)	2.80

Authors

Authors	Studies
Bacáková, L; El-Fakahany, EE; Jakubík, J; Tucek, S	1
Go, ML; Sim, MK; Xu, R	1
Bernhardt, G; Gmeiner, P; Hübner, H; Keller, M; Pegoli, A; She, X; Wifling, D	1
Bernhardt, G; Carpenter, J; Chen, M; Gmeiner, P; Gruber, CG; Holliday, ND; Hübner, H; Keller, M; Pegoli, A; She, X; Wan, J; Wifling, D	1
Lüllmann, H; Mohr, K	1
Ehlert, FJ; Gerstin, EH; Luong, T	1
Aronstam, RS; Catravas, JD; Ryan, US	1
Jakobs, KH; Liebmann, C; Nawrath, S; Schnittler, M; Schubert, H	1
Ehlert, FJ; Griffin, MT; Hsu, HH; Hunter, AL; Luong, T; Thomas, EA	1
Bauer, A; Schulz, JB; Zilles, K	1
Hacksell, U; Nilsson, BM; Ringdahl, B; Vargas, HM	1
Davidson, RK; Dilsaver, SC; Majchrzak, MJ; Snider, RM	1
Ballesteros, LA; Bichajian, LH; Ferrendelli, CA; Fisher, A; Hanchett, HE; Potter, LT; Zhang, R	1
Findlay, JB; Saunders, J	1
Dilsaver, SC; Flemmer, DD; Peck, JA	2
Delen, FM; Ehlert, FJ; Liem, HA; Yun, SH	1
Baker, R; Freedman, SB; MacLeod, AM; Merchant, KJ; Patel, S; Roe, M; Saunders, J	1
Ehlert, FJ; Rathbun, BE	1
Kellar, KJ; Price, DL; Wagster, MV; Walker, LC; Whitehouse, PJ	1
Birdsall, NJ; Curtis, C; Eveleigh, P; Hulme, EC; Pedder, EK; Poyner, DR; Wheatley, M	1
Hollingsworth, PJ; Smith, CB	1
Hacksell, U; Lundkvist, JR; Ringdahl, B	1
Brunner, F; Christophe, J; Gillard, M; Svoboda, M; Waelbroeck, M	1
Cross, AJ; Green, AR; Hunter, AJ; Jones, JA; Murray, TK	1
Delen, FM; Ehlert, FJ; Friedman, DJ; Self, DW; Yun, SH	1
Ek, B; Nahorski, S	1
Kito, S; Matsubayashi, H; Miyoshi, R; Mizuno, K	1
Bleakman, D; Naftalin, RJ	1
Anderson, W; Dickinson, KE; Hirschowitz, BI; Matsumoto, H; Pruitt, RE; Uemura, N	1
Chuang, DM; Xu, J	1
Anthony, BL; Aronstam, RS; Dennison, RL; Narayanan, TK	1
Ehlert, FJ	4
Lüllmann, H; Mohr, K; Pfeffer, J	1
Abdel-Latif, AA; Honkanen, RE	1
Baker, R; Freedman, SB; Harley, EA; Saunders, J; Showell, GA; Snow, RJ	1
Freedman, SB; Harley, EA; Iversen, LL	1
Chiang, PK; Gordon, RK; Witkin, JM	1
Hamm, RJ; Knisely, JS	1
Christophe, J; Gillard, M; Waelbroeck, M	1
Birdsall, NJ; Hulme, EC; Keen, M	1
Chien, JL; Warren, JR	1
Baker, SP; Posner, P	1
Ehlert, FJ; Jenden, DJ	1
Ahlenius, S; Larsson, K	1
Berrie, CP; Birdsall, NJ; Hulme, EC; Keen, M; Stockton, JM	1
Sillén, U	1
Bevan, P	1
Driscoll, P; Gentsch, C; Martin, JR	1
Christophe, J; De Neef, P; Robberecht, P; Waelbroeck, M	3
Daniotti, S; Del Soldato, P	1
Kuhar, MJ; Lepor, H	1
Klein, WL; Siman, RG	1
Birdsall, NJ; De Belleroche, J; Hulme, EC; Kilpatrick, IC	1
Hjälmås, K; Rubenson, A; Sillén, U	1
Glick, SD; Guido, RA	1
Orpen, G; Steiner, M	1
DeSantis, LM; Sharif, NA; Williams, GW	1
Herremans, AH; Hijzen, TH; Olivier, B; Slangen, JL	1
Wells, JW; Wreggett, KA	1
Kostenis, E; Maass, A; Mohr, K	1
Luthin, GR; Ruggieri, MR; Wang, P	1
Freedman, SB; Patel, S	1
Fisher, SK; Levey, AI; Slowiejko, DM	1
Kramss, RH; Mangano, RM; Trybulski, EJ; Zhang, J	1
Antonsson, BM; Ek, B	1
Eglen, RM; Sharif, NA; To, ZP	1
Consolo, S; Garcia Ruiz, AJ; La Porta, C; Ladinsky, H; Zambelli, M	1
Cristi, C; Raithby, A; Snider, M; Tanner, C; Vanderwolf, CH	1
Jones, SB; King, LB	1
Alemán, V; del Guante, MA; Ortega, A; Prado-Alcalá, RA	1
Cheng, E; Cline, RT; Fraser, CM; Geoghagen, NS; Lee, NH	1
Maass, A; Mohr, K	1
Ala, TA; Aldrich, SL; Anderson, LE; Bordayo, EZ; Fawcett, JR; Fraticelli, AI; Frey, WH; Johnson, MN; Kjome, JR; Klevan, LC; Swenson, KA; Venters, HD	1
Chahdi, A; Daeffler, L; Gies, JP; Landry, Y	1
Amenta, F; Natale, D; Piergentili, A; Tayebati, SK	1
Curtis, CA; Hulme, EC; Ward, SD	1
Azpiazu, I; Cruzblanca, H; Gautam, N; Li, P; Linder, M; Zhuo, M	1
Chang, DJ; Cho, NJ; Hwang, JM; Kaang, BK; Kim, US; Lee, YS; Park, YS	1
Cordon, CJ; Padnos, B; Smith, EC	1
Park, PS; Sum, CS; Wells, JW	1
Ehlert, FJ; Griffin, MT; Hsu, JC; Shehnaz, D	1
Antony, J; Grossmüller, M; Holzgrabe, U; Mohr, K; Tränkle, C	1
Barak, D; Pittel, Z; Segall, Y	1
Angers, S; Ma, AW; Pisterzi, LF; Redka, DS; Wells, JW	1
Grauer, E; Levy, A	1
Blackstone, K; Pratt, WE	1
Charlton, SJ; Dowling, MR; Sykes, DA	1

Reviews

1 review(s) available for n-methylscopolamine and oxotremorine

Article	Year
Cardioselective muscarinic antagonists. Federation proceedings, 1987, Volume: 46, Issue:8 Topics: Animals; Carbachol; Cardiotonic Agents; Carrier Proteins; Cyclic AMP; Cyclic AMP Receptor Protein; Dose-Response Relationship, Drug; Heart; N-Methylscopolamine; Oxotremorine; Phorbol Esters; Pirenzepine; Receptors, Adrenergic; Receptors, Cholinergic; Receptors, Muscarinic; Scopolamine Derivatives	1987

Other Studies

93 other study(ies) available for n-methylscopolamine and oxotremorine

Article	Year
Positive cooperativity of acetylcholine and other agonists with allosteric ligands on muscarinic acetylcholine receptors. Molecular pharmacology, 1997, Volume: 52, Issue:1 Topics: Acetylcholine; Allosteric Regulation; Animals; Binding, Competitive; CHO Cells; Cricetinae; Ligands; Muscarinic Agonists; N-Methylscopolamine; Receptors, Muscarinic; Scopolamine Derivatives	1997
Synthesis and pharmacological characterization of O-alkynyloximes of tropinone and N-methylpiperidinone as muscarinic agonists. Journal of medicinal chemistry, 1998, Aug-13, Volume: 41, Issue:17 Topics: Animals; Aorta; Binding, Competitive; Drug Design; Escape Reaction; In Vitro Techniques; Male; Maze Learning; Mice; Models, Molecular; Molecular Structure; Muscarinic Agonists; Muscle Contraction; Muscle, Smooth, Vascular; N-Methylscopolamine; Nuclear Magnetic Resonance, Biomolecular; Piperidines; Pirenzepine; Rabbits; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Structure-Activity Relationship; Tropanes	1998
Radiolabeled Dibenzodiazepinone-Type Antagonists Give Evidence of Dualsteric Binding at the M Journal of medicinal chemistry, 2017, 04-27, Volume: 60, Issue:8 Topics: Benzodiazepinones; Binding Sites; Molecular Dynamics Simulation; Muscarinic Antagonists; Radioisotopes; Receptor, Muscarinic M2	2017
Red-Emitting Dibenzodiazepinone Derivatives as Fluorescent Dualsteric Probes for the Muscarinic Acetylcholine M Journal of medicinal chemistry, 2020, 04-23, Volume: 63, Issue:8 Topics: Animals; CHO Cells; Cholinergic Agents; Cricetulus; Fluorescent Dyes; Muscarinic Antagonists; Phthalimides; Protein Structure, Secondary; Quaternary Ammonium Compounds; Receptor, Muscarinic M2	2020
C14-aminosteroid LNF 209, an agent with positive inotropic and antimuscarinic activity. Journal of cardiovascular pharmacology, 1992, Volume: 20, Issue:5 Topics: Androstanes; Animals; Binding Sites; Cardiotonic Agents; Female; Guinea Pigs; Heart Atria; Ileum; In Vitro Techniques; Male; Mannosides; Myocardial Contraction; Myocardium; N-Methylscopolamine; Ouabain; Oxotremorine; Parasympatholytics; Radioligand Assay; Receptors, Muscarinic; Scopolamine Derivatives; Stimulation, Chemical	1992
Heparin, dextran and trypan blue allosterically modulate M2 muscarinic receptor binding properties and interfere with receptor-mediated inhibition of adenylate cyclase. The Journal of pharmacology and experimental therapeutics, 1992, Volume: 263, Issue:3 Topics: Adenylyl Cyclase Inhibitors; Allosteric Regulation; Animals; Dextrans; Dose-Response Relationship, Drug; Heparin; In Vitro Techniques; Male; Myocardium; N-Methylscopolamine; Oxotremorine; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Scopolamine Derivatives; Trypan Blue	1992
Muscarinic binding sites on bovine pulmonary arterial endothelial cells in culture. Pharmacology, 1992, Volume: 44, Issue:6 Topics: Allosteric Site; Animals; Binding Sites; Cattle; Cells, Cultured; Endothelium, Vascular; Muscarinic Antagonists; N-Methylscopolamine; Oxotremorine; Parasympatholytics; Parasympathomimetics; Pulmonary Artery; Quinuclidinyl Benzilate; Radioligand Assay; Receptors, Muscarinic; Scopolamine Derivatives	1992
Binding characteristics and functional G protein coupling of muscarinic acetylcholine receptors in rat duodenum smooth muscle membranes. Naunyn-Schmiedeberg's archives of pharmacology, 1992, Volume: 345, Issue:1 Topics: Animals; Binding Sites; Binding, Competitive; Cell Membrane; Cerebral Cortex; Duodenum; Female; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Kinetics; Male; Muscle, Smooth; Myocardium; N-Methylscopolamine; Oxotremorine; Parasympatholytics; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Scopolamine Derivatives; Submandibular Gland	1992
Conversion of N-(2-chloroethyl)-4-piperidinyl diphenylacetate (4-DAMP mustard) to an aziridinium ion and its interaction with muscarinic receptors in various tissues. Molecular pharmacology, 1992, Volume: 41, Issue:4 Topics: Alkylation; Animals; Aziridines; Binding Sites; Brain; Diphenylacetic Acids; Drug Interactions; Hydrogen-Ion Concentration; Ileum; In Vitro Techniques; Kinetics; Male; Myocardium; N-Methylscopolamine; Oxotremorine; Piperidines; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Scopolamine Derivatives; Submandibular Gland; Temperature	1992
Muscarinic desensitization after septal lesions in rat hippocampus: evidence for the involvement of G-proteins. Neuroscience, 1992, Volume: 47, Issue:1 Topics: Animals; GTP-Binding Proteins; Guanylyl Imidodiphosphate; Hippocampus; Ibotenic Acid; Kinetics; Male; N-Methylscopolamine; Oxotremorine; Parasympatholytics; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Scopolamine Derivatives	1992
Phenyl-substituted analogues of oxotremorine as muscarinic antagonists. Journal of medicinal chemistry, 1992, Jan-24, Volume: 35, Issue:2 Topics: Animals; Binding, Competitive; Cerebral Cortex; Guinea Pigs; In Vitro Techniques; Magnetic Resonance Spectroscopy; Male; Mice; Muscle, Smooth; N-Methylscopolamine; Oxotremorine; Parasympatholytics; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Scopolamine Derivatives; Structure-Activity Relationship; Tremor	1992
A nicotinic receptor antagonist enhances the hypothermic response to a muscarinic agonist. Progress in neuro-psychopharmacology & biological psychiatry, 1991, Volume: 15, Issue:4 Topics: Animals; Body Temperature; Male; Mecamylamine; N-Methylscopolamine; Oxotremorine; Parasympathomimetics; Rats; Rats, Inbred Strains; Receptors, Nicotinic; Scopolamine Derivatives	1991
Evidence of paired M2 muscarinic receptors. Molecular pharmacology, 1991, Volume: 39, Issue:2 Topics: Animals; Binding Sites; Binding, Competitive; Brain Stem; Buffers; GTP-Binding Proteins; Guanine Nucleotides; Kinetics; Ligands; Male; Muscarinic Antagonists; Myocardium; N-Methylscopolamine; Oxotremorine; Parasympatholytics; Quinuclidinyl Benzilate; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Scopolamine Derivatives; Tritium	1991
Monoamine neurotransmitter receptors: ligand-receptor models. Biochemical Society symposium, 1990, Volume: 57 Topics: Animals; Binding Sites; Ligands; Models, Chemical; Molecular Structure; N-Methylscopolamine; Neurotransmitter Agents; Oxotremorine; Receptors, Muscarinic; Receptors, Neurotransmitter; Scopolamine Derivatives	1990
Exposure to constant darkness enhances the thermic response of the rat to a muscarinic agonist. Pharmacology, biochemistry, and behavior, 1991, Volume: 38, Issue:1 Topics: Animals; Body Temperature; Darkness; Dose-Response Relationship, Drug; Male; N-Methylscopolamine; Oxotremorine; Parasympatholytics; Parasympathomimetics; Rats; Rats, Inbred Strains; Scopolamine Derivatives	1991
Bright light blocks the capacity of inescapable swim stress to supersensitize a central muscarinic mechanism. Pharmacology, biochemistry, and behavior, 1990, Volume: 36, Issue:4 Topics: Animals; Body Temperature; Light; N-Methylscopolamine; Oxotremorine; Parasympatholytics; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Scopolamine Derivatives; Stress, Psychological; Swimming	1990
The interaction of amitriptyline, doxepin, imipramine and their N-methyl quaternary ammonium derivatives with subtypes of muscarinic receptors in brain and heart. The Journal of pharmacology and experimental therapeutics, 1990, Volume: 253, Issue:1 Topics: Adenylyl Cyclase Inhibitors; Amitriptyline; Animals; Brain; Doxepin; Heart; Imipramine; In Vitro Techniques; Male; N-Methylscopolamine; Oxotremorine; Pirenzepine; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Scopolamine Derivatives	1990
Synthesis and muscarinic activities of 1,2,4-thiadiazoles. Journal of medicinal chemistry, 1990, Volume: 33, Issue:7 Topics: Animals; Binding, Competitive; Cerebral Cortex; Indicators and Reagents; Kinetics; Ligands; Models, Molecular; Molecular Structure; N-Methylscopolamine; Oxotremorine; Parasympathomimetics; Rats; Receptors, Muscarinic; Scopolamine Derivatives; Structure-Activity Relationship; Thiadiazoles; X-Ray Diffraction	1990
Signaling through the muscarinic receptor-adenylate cyclase system of the heart is buffered against GTP over a range of concentrations. Molecular pharmacology, 1990, Volume: 38, Issue:1 Topics: Adenylyl Cyclase Inhibitors; Animals; Carbachol; Guanosine Triphosphate; Male; Myocardium; N-Methylscopolamine; Oxotremorine; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Scopolamine Derivatives	1990
Laminar organization and age-related loss of cholinergic receptors in temporal neocortex of rhesus monkey. The Journal of neuroscience : the official journal of the Society for Neuroscience, 1990, Volume: 10, Issue:9 Topics: Aging; Animals; Autoradiography; Macaca mulatta; N-Methylscopolamine; Oxotremorine; Pirenzepine; Receptors, Cholinergic; Receptors, Muscarinic; Receptors, Nicotinic; Scopolamine Derivatives; Temporal Lobe; Tissue Distribution	1990
Binding and hydrodynamic properties of muscarinic receptor subtypes solubilized in 3-(3-cholamidopropyl)dimethylammonio-2-hydroxy-1-propanesulfonate. Molecular pharmacology, 1989, Volume: 36, Issue:3 Topics: Animals; Cell Membrane; Centrifugation, Density Gradient; Cerebral Cortex; Cholic Acids; Detergents; GTP-Binding Proteins; Guanylyl Imidodiphosphate; Lacrimal Apparatus; Myocardium; N-Methylscopolamine; Oxotremorine; Rats; Receptors, Muscarinic; Scopolamine Derivatives; Solubility	1989
Effects of muscarinic receptor agonists and antagonists on alpha 2-adrenoceptors in rat brain. European journal of pharmacology, 1989, Sep-13, Volume: 168, Issue:2 Topics: Animals; Atropine; Atropine Derivatives; Brain; Clonidine; Male; N-Methylscopolamine; Neurons; Oxotremorine; Parasympatholytics; Pilocarpine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Muscarinic; Scopolamine; Scopolamine Derivatives; Time Factors	1989
Conformationally restricted analogues of the muscarinic agent N-methyl-N-(1-methyl-4-pyrrolidino-2-butynyl)acetamide. Journal of medicinal chemistry, 1989, Volume: 32, Issue:4 Topics: Animals; Biological Assay; Cerebral Cortex; Chemical Phenomena; Chemistry; Guinea Pigs; Ileum; Mice; Molecular Conformation; Muscle Contraction; N-Methylscopolamine; Oxotremorine; Parasympathomimetics; Pyrrolidines; Rats; Receptors, Muscarinic; Scopolamine Derivatives; Structure-Activity Relationship; Tremor	1989
Bretylium tosylate binds preferentially to muscarinic receptors labelled with [3H]oxotremorine M (SH or 'high affinity' receptors) in rat heart and brain cortex. European journal of pharmacology, 1989, Jan-24, Volume: 160, Issue:1 Topics: Animals; Bretylium Compounds; Bretylium Tosylate; Cerebral Cortex; Guanosine Triphosphate; Heart; In Vitro Techniques; Male; Membranes; Myocardium; N-Methylscopolamine; Oxotremorine; Pilocarpine; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Scopolamine Derivatives	1989
The cholinergic pharmacology of tetrahydroaminoacridine in vivo and in vitro. British journal of pharmacology, 1989, Volume: 98, Issue:1 Topics: Aminoacridines; Animals; Behavior, Animal; Brain Chemistry; Cholinesterase Inhibitors; Gallamine Triethiodide; In Vitro Techniques; Male; Mice; Myocardium; N-Methylscopolamine; Nicotine; Oxotremorine; Parasympathetic Nervous System; Physostigmine; Pirenzepine; Rats; Receptors, Muscarinic; Scopolamine Derivatives; Tacrine	1989
Coupling of subtypes of the muscarinic receptor to adenylate cyclase in the corpus striatum and heart. The Journal of pharmacology and experimental therapeutics, 1989, Volume: 251, Issue:2 Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Binding, Competitive; Corpus Striatum; Gallamine Triethiodide; Male; Myocardium; N-Methylscopolamine; Oxotremorine; Pirenzepine; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Muscarinic; RNA, Messenger; Scopolamine Derivatives	1989
Muscarinic receptor coupling to inositol phospholipid metabolism in guinea-pig cerebral cortex, parotid gland and ileal smooth muscle. Biochemical pharmacology, 1988, Dec-01, Volume: 37, Issue:23 Topics: Animals; Atropine; Carbachol; Cerebral Cortex; Guanosine Triphosphate; Guinea Pigs; Ileum; Muscle, Smooth; N-Methylscopolamine; Oxotremorine; Parotid Gland; Phosphatidylinositols; Pirenzepine; Receptors, Muscarinic; Scopolamine Derivatives	1988
Effects of somatostatin on muscarinic acetylcholine receptor binding in the rat hippocampus. Japanese journal of pharmacology, 1986, Volume: 40, Issue:2 Topics: Animals; Binding Sites; Hippocampus; Kinetics; Male; N-Methylscopolamine; Oxotremorine; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Scopolamine Derivatives; Somatostatin; Tritium	1986
Prevention of guanine nucleotide-induced reductions in muscarinic agonist binding to rabbit ileal submucosal membranes by lidamidine and tetracaine. Naunyn-Schmiedeberg's archives of pharmacology, 1988, Volume: 337, Issue:4 Topics: Adrenergic beta-Agonists; Animals; Guanine Nucleotides; Guanylyl Imidodiphosphate; Ileum; In Vitro Techniques; Intestinal Mucosa; N-Methylscopolamine; Oxotremorine; Phenylurea Compounds; Rabbits; Receptors, Muscarinic; Scopolamine Derivatives; Sodium Fluoride; Tetracaine	1988
Muscarinic cholinergic receptor subtype on frog esophageal peptic cells: binding and secretion studies. The Journal of pharmacology and experimental therapeutics, 1988, Volume: 246, Issue:3 Topics: Acetylcholine; Animals; Atropine; Bethanechol; Bethanechol Compounds; Carbachol; Esophagus; Imipramine; Kinetics; N-Methylscopolamine; Oxotremorine; Pepsinogens; Pirenzepine; Propranolol; Radioligand Assay; Rana catesbeiana; Receptors, Muscarinic; Scopolamine Derivatives	1988
Muscarinic acetylcholine receptor-mediated phosphoinositide turnover in cultured cerebellar granule cells: desensitization by receptor agonists. The Journal of pharmacology and experimental therapeutics, 1987, Volume: 242, Issue:1 Topics: Animals; Atropine; Carbachol; Cells, Cultured; Cerebellum; Kinetics; Male; N-Methylscopolamine; Oxotremorine; Phorbol Esters; Phosphatidylinositols; Pirenzepine; Quinuclidinyl Benzilate; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Scopolamine Derivatives; Virulence Factors, Bordetella	1987
Effects of halothane on high affinity agonist binding and guanine nucleotide sensitivity of muscarinic acetylcholine receptors from brainstem of rat. Neuropharmacology, 1987, Volume: 26, Issue:8 Topics: Animals; Brain Stem; GTP-Binding Proteins; Guanine Nucleotides; Guanylyl Imidodiphosphate; Halothane; Kinetics; Male; N-Methylscopolamine; Oxotremorine; Rats; Rats, Inbred Strains; Receptors, Cholinergic; Scopolamine Derivatives	1987
Gallamine allosterically antagonizes muscarinic receptor-mediated inhibition of adenylate cyclase activity in the rat myocardium. The Journal of pharmacology and experimental therapeutics, 1988, Volume: 247, Issue:2 Topics: Adenylyl Cyclase Inhibitors; Algorithms; Animals; Dose-Response Relationship, Drug; Gallamine Triethiodide; Heart; Male; Myocardium; N-Methylscopolamine; Oxotremorine; Pyrrolidines; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Scopolamine Derivatives	1988
Release of N-[3H]methylscopolamine from isolated guinea pig atria is controlled by diffusion and rebinding. The Journal of pharmacology and experimental therapeutics, 1988, Volume: 247, Issue:2 Topics: Animals; Carbachol; Diffusion; Female; Guinea Pigs; Heart Atria; Male; Membranes; Myocardium; N-Methylscopolamine; Oxotremorine; Receptors, Muscarinic; Scopolamine Derivatives; Time Factors	1988
Characterization of cholinergic muscarinic receptors in the rabbit iris. Biochemical pharmacology, 1988, Jul-01, Volume: 37, Issue:13 Topics: Animals; Atropine; Carbachol; Cerebral Cortex; Ileum; Iris; Kinetics; Methacholine Chloride; Methacholine Compounds; Microsomes; N-Methylscopolamine; Oxotremorine; Pirenzepine; Quinuclidinyl Benzilate; Rabbits; Receptors, Muscarinic; Scopolamine Derivatives	1988
2-Methyl-1,3-dioxaazaspiro[4.5]decanes as novel muscarinic cholinergic agonists. Journal of medicinal chemistry, 1988, Volume: 31, Issue:2 Topics: Animals; Bridged Bicyclo Compounds; Bridged-Ring Compounds; Dioxolanes; Dioxoles; In Vitro Techniques; Inositol Phosphates; Male; Molecular Conformation; N-Methylscopolamine; Oxotremorine; Parasympathomimetics; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Scopolamine Derivatives; Spiro Compounds; Structure-Activity Relationship	1988
Relative affinities of drugs acting at cholinoceptors in displacing agonist and antagonist radioligands: the NMS/Oxo-M ratio as an index of efficacy at cortical muscarinic receptors. British journal of pharmacology, 1988, Volume: 93, Issue:2 Topics: Animals; Binding, Competitive; Cerebral Cortex; In Vitro Techniques; Inositol; Male; N-Methylscopolamine; Oxotremorine; Phospholipids; Rats; Receptors, Cholinergic; Receptors, Muscarinic; Scopolamine Derivatives; Synaptosomes	1988
Comparison of in vitro actions with behavioral effects of antimuscarinic agents. The Journal of pharmacology and experimental therapeutics, 1987, Volume: 242, Issue:3 Topics: alpha-Amylases; Animals; Behavior, Animal; Dose-Response Relationship, Drug; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; N-Methylscopolamine; Oxotremorine; Parasympatholytics; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Scopolamine Derivatives; Structure-Activity Relationship	1987
Developmental differences in the analgesia produced by the central cholinergic system. Developmental psychobiology, 1987, Volume: 20, Issue:3 Topics: Age Factors; Animals; Male; N-Methylscopolamine; Oxotremorine; Pain; Rats; Rats, Inbred Strains; Reaction Time; Receptors, Muscarinic; Scopolamine; Scopolamine Derivatives; Sensory Thresholds	1987
Effects of an alkylating derivative of oxotremorine (BM 123A) on heart rate, muscarinic receptors and adenylate cyclase activity in the rabbit myocardium. The Journal of pharmacology and experimental therapeutics, 1987, Volume: 241, Issue:3 Topics: Adenylyl Cyclases; Animals; Aziridines; Azirines; Guanosine Triphosphate; Heart Rate; Male; Mathematics; Myocardium; N-Methylscopolamine; Oxotremorine; Pyrrolidinones; Rabbits; Receptors, Muscarinic; Scopolamine Derivatives	1987
Muscarinic receptor heterogeneity in rat central nervous system. II. Brain receptors labeled by [3H]oxotremorine-M correspond to heterogeneous M2 receptors with very high affinity for agonists. Molecular pharmacology, 1987, Volume: 32, Issue:1 Topics: Animals; Binding, Competitive; Brain; Carbachol; Cerebral Cortex; Kinetics; Male; Myocardium; N-Methylscopolamine; Oxotremorine; Parasympatholytics; Pilocarpine; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Scopolamine Derivatives	1987
The binding of pirenzepine to digitonin-solubilized muscarinic acetylcholine receptors from the rat myocardium. British journal of pharmacology, 1986, Volume: 87, Issue:2 Topics: Animals; Benzodiazepinones; Binding, Competitive; Cell Membrane; Centrifugation, Density Gradient; Digitonin; In Vitro Techniques; Myocardium; N-Methylscopolamine; Oxotremorine; Pirenzepine; Rats; Receptors, Muscarinic; Scopolamine Derivatives; Solubility	1986
Muscarinic receptor coupling to intracellular calcium release in rat pancreatic acinar carcinoma. Cancer research, 1986, Volume: 46, Issue:11 Topics: Animals; Binding, Competitive; Calcium; Carbachol; Carcinoma; N-Methylscopolamine; Oxotremorine; Pancreatic Neoplasms; Proteins; Rats; Rats, Inbred F344; Receptors, Muscarinic; Scopolamine Derivatives	1986
Irreversible binding of acetylethylcholine mustard to cardiac cholinergic muscarinic receptors. Molecular pharmacology, 1986, Volume: 30, Issue:5 Topics: Acetylcholine; Animals; Atropine; Carbachol; Cell Membrane; Guanylyl Imidodiphosphate; Heart Rate; Male; Myocardium; N-Methylscopolamine; Oxotremorine; Quinuclidinyl Benzilate; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Scopolamine Derivatives	1986
Coupling of muscarinic receptors to adenylate cyclase in the rabbit myocardium: effects of receptor inactivation. The Journal of pharmacology and experimental therapeutics, 1987, Volume: 240, Issue:1 Topics: Adenylyl Cyclases; Alkylation; Animals; Binding, Competitive; Choline; Dithiothreitol; Dose-Response Relationship, Drug; Guanosine Triphosphate; Kinetics; Male; Mathematics; Myocardium; N-Methylscopolamine; Oxotremorine; Quinuclidinyl Benzilate; Rabbits; Receptors, Muscarinic; Scopolamine Derivatives	1987
The binding of a 2-chloroethylamine derivative of oxotremorine (BM 123) to muscarinic receptors in the rat cerebral cortex. Molecular pharmacology, 1985, Volume: 28, Issue:2 Topics: Alkylation; Animals; Atropine; Benzodiazepinones; Binding Sites; Binding, Competitive; Cerebral Cortex; Gallamine Triethiodide; Kinetics; N-Methylscopolamine; Oxotremorine; Pirenzepine; Pyrrolidinones; Quinuclidinyl Benzilate; Rats; Receptors, Muscarinic; Scopolamine Derivatives; Structure-Activity Relationship; Thiosulfates	1985
Central muscarinic receptors and male rat sexual behavior: facilitation by oxotremorine but not arecoline or pilocarpine in methscopolamine pretreated animals. Psychopharmacology, 1985, Volume: 87, Issue:2 Topics: Animals; Arecoline; Dose-Response Relationship, Drug; Female; Male; N-Methylscopolamine; Oxotremorine; Pilocarpine; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Scopolamine Derivatives; Sexual Behavior, Animal	1985
Solubilization and characterization of high and low affinity pirenzepine binding sites from rat cerebral cortex. British journal of pharmacology, 1985, Volume: 85, Issue:3 Topics: Animals; Binding, Competitive; Centrifugation, Density Gradient; Cerebral Cortex; Digitonin; In Vitro Techniques; N-Methylscopolamine; Oxotremorine; Quinuclidinyl Benzilate; Rats; Receptors, Muscarinic; Scopolamine Derivatives; Solubility	1985
The relationship between muscarinic receptor occupancy and adenylate cyclase inhibition in the rabbit myocardium. Molecular pharmacology, 1985, Volume: 28, Issue:5 Topics: Adenylyl Cyclase Inhibitors; Animals; Carbachol; Guanosine Triphosphate; In Vitro Techniques; Male; Models, Structural; Myocardium; N-Methylscopolamine; Oxotremorine; Rabbits; Receptors, Muscarinic; Scopolamine Derivatives; Tritium	1985
Central neurotransmitter mechanisms involved in the control of urinary bladder function. An experimental study in the rat. Scandinavian journal of urology and nephrology. Supplementum, 1980, Volume: 58 Topics: Animals; Brain; Diazepam; Levodopa; Male; Models, Biological; Muscimol; N-Methylscopolamine; Neurotransmitter Agents; Oxotremorine; Rats; Receptors, Cell Surface; Receptors, Dopamine; Receptors, GABA-A; Receptors, Muscarinic; Scopolamine Derivatives; Urinary Bladder	1980
Effect of muscarinic ligands on the electrical activity recorded from the hippocampus: a quantitative approach. British journal of pharmacology, 1984, Volume: 82, Issue:2 Topics: Amphetamine; Animals; Arecoline; Bromocriptine; Electrophysiology; Hippocampus; Injections, Intravenous; Male; N-Methylscopolamine; Neurons, Afferent; Oxotremorine; Parasympathetic Nervous System; Parasympathomimetics; Rats; Receptors, Muscarinic; Scopolamine Derivatives; Stereotaxic Techniques	1984
Differential response to cholinergic stimulation in psychogenitically selected rat lines. Psychopharmacology, 1984, Volume: 83, Issue:3 Topics: Animals; Body Temperature; Female; Male; N-Methylscopolamine; Oxotremorine; Parasympathetic Nervous System; Rats; Rats, Inbred Strains; Salivation; Scopolamine; Scopolamine Derivatives; Tears; Tremor	1984
Inhibitory effects of quinidine on rat heart muscarinic receptors. Life sciences, 1984, Sep-03, Volume: 35, Issue:10 Topics: Animals; Atropine; Binding, Competitive; Heart; Kinetics; Mathematics; Myocardium; N-Methylscopolamine; Oxotremorine; Quinidine; Rats; Receptors, Muscarinic; Scopolamine Derivatives	1984
Comparative studies of the effects of some antimuscarinic agents on gastric damage and pupillary reflex in the rat. British journal of pharmacology, 1984, Volume: 82, Issue:2 Topics: Animals; Atropine; Benzodiazepinones; Female; N-Methylscopolamine; Oxotremorine; Parasympatholytics; Pirenzepine; Propantheline; Rats; Rats, Inbred Strains; Reflex, Pupillary; Scopolamine Derivatives; Stomach Diseases	1984
Effects of verapamil on the binding properties of rat heart muscarinic receptors: evidence for an allosteric site. Biochemical and biophysical research communications, 1984, May-31, Volume: 121, Issue:1 Topics: Allosteric Site; Animals; Binding, Competitive; Kinetics; Myocardium; N-Methylscopolamine; Oxotremorine; Rats; Receptors, Muscarinic; Scopolamine Derivatives; Verapamil	1984
Characterization of muscarinic cholinergic receptor binding in the vas deferens, bladder, prostate and penis of the rabbit. The Journal of urology, 1984, Volume: 132, Issue:2 Topics: Animals; Atropine; Binding, Competitive; Diazoxide; Haloperidol; In Vitro Techniques; Male; N-Methylscopolamine; Oxotremorine; Parasympathomimetics; Penis; Phentolamine; Propranolol; Prostate; Rabbits; Radioligand Assay; Receptors, Muscarinic; Scopolamine Derivatives; Urinary Bladder; Vas Deferens	1984
Multiple effects of short-chain alcohols on binding to rat heart muscarinic receptors. The Biochemical journal, 1984, Apr-15, Volume: 219, Issue:2 Topics: 1-Propanol; Animals; Ethanol; Heart; In Vitro Techniques; Kinetics; Macromolecular Substances; Methanol; Myocardium; N-Methylscopolamine; Oxotremorine; Rats; Receptors, Muscarinic; Scopolamine Derivatives	1984
Differential regulation of muscarinic and nicotinic receptors by cholinergic stimulation in cultured avian retina cells. Brain research, 1983, Feb-28, Volume: 262, Issue:1 Topics: Animals; Atropine; Carbachol; Cells, Cultured; Chick Embryo; N-Methylscopolamine; Neurons; Nicotine; Oxotremorine; Quinuclidinyl Benzilate; Receptors, Cholinergic; Receptors, Muscarinic; Receptors, Nicotinic; Retina; Scopolamine Derivatives; Tubocurarine	1983
Presynaptic muscarinic receptors on dopaminergic terminals in the nucleus accumbens. Brain research, 1982, Feb-25, Volume: 234, Issue:2 Topics: Animals; Dopamine; Male; N-Methylscopolamine; Nucleus Accumbens; Oxotremorine; Propylbenzilylcholine Mustard; Quinuclidinyl Benzilate; Rats; Rats, Inbred Strains; Receptors, Cholinergic; Receptors, Dopamine; Receptors, Muscarinic; Scopolamine Derivatives; Septal Nuclei; Synapses; Tegmentum Mesencephali	1982
Central cholinergic mechanisms in L-DOPA induced hyperactive urinary bladder of the rat. Urological research, 1982, Volume: 10, Issue:5 Topics: Animals; Atropine; Brain; Calcium; Hexamethonium Compounds; Levodopa; Male; N-Methylscopolamine; Oxotremorine; Phentolamine; Rats; Receptors, Adrenergic; Receptors, Cholinergic; Reserpine; Scopolamine Derivatives; Sotalol; Urinary Bladder	1982
Scopolamine self-administration: cholinergic involvement in reward mechanisms. Life sciences, 1982, Aug-30, Volume: 31, Issue:9 Topics: Animals; Arecoline; Atropine; Behavior, Animal; Female; Mecamylamine; N-Methylscopolamine; Oxotremorine; Parasympathetic Nervous System; Physostigmine; Pilocarpine; Rats; Rats, Inbred Strains; Reinforcement, Psychology; Reward; Scopolamine; Scopolamine Derivatives; Self Administration	1982
The WAGxDA rat: an animal model of cholinergic supersensitivity. Biological psychiatry, 1995, Jun-15, Volume: 37, Issue:12 Topics: Animals; Autonomic Nervous System Diseases; Behavior, Animal; Body Temperature; Brain Chemistry; Disease Models, Animal; Female; Kinetics; Male; Muscarinic Agonists; N-Methylscopolamine; Oxotremorine; Parasympathetic Nervous System; Parasympatholytics; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Scopolamine Derivatives; Stress, Psychological	1995
Affinities of muscarinic drugs for [3H]N-methylscopolamine (NMS) and [3H]oxotremorine (OXO) binding to a mixture of M1-M4 muscarinic receptors: use of NMS/OXO-M ratios to group compounds into potential agonist, partial agonist, and antagonist classes. Neurochemical research, 1995, Volume: 20, Issue:6 Topics: Animals; Binding, Competitive; Brain; Cholinergic Agents; Kinetics; Lung; Muscarinic Agonists; Muscarinic Antagonists; Myocardium; N-Methylscopolamine; Oxotremorine; Rabbits; Radioligand Assay; Rats; Receptors, Muscarinic; Scopolamine Derivatives; Tritium	1995
Cholinergic drug effects on a delayed conditional discrimination task in the rat. Behavioral neuroscience, 1995, Volume: 109, Issue:3 Topics: Animals; Appetitive Behavior; Arecoline; Brain; Conditioning, Operant; Discrimination Learning; Dose-Response Relationship, Drug; Injections, Intraperitoneal; Male; Mental Recall; N-Methylscopolamine; Oxotremorine; Parasympatholytics; Physostigmine; Rats; Rats, Wistar; Receptors, Cholinergic; Retention, Psychology; Scopolamine; Scopolamine Derivatives; Synaptic Transmission; Tacrine	1995
Cooperativity manifest in the binding properties of purified cardiac muscarinic receptors. The Journal of biological chemistry, 1995, Sep-22, Volume: 270, Issue:38 Topics: Allosteric Regulation; Animals; GTP-Binding Proteins; Guanylyl Imidodiphosphate; In Vitro Techniques; Molecular Weight; Muscarinic Antagonists; Myocardium; N-Methylscopolamine; Oxotremorine; Parasympatholytics; Pirenzepine; Quinuclidinyl Benzilate; Radioligand Assay; Receptors, Muscarinic; Sarcolemma; Scopolamine Derivatives; Swine	1995
Potentiation by alcuronium of the antimuscarinic effect of N-methylscopolamine in guinea pig left atria. European journal of pharmacology, 1995, Jan-05, Volume: 272, Issue:1 Topics: Alcuronium; Allosteric Regulation; Animals; Atrial Function; Binding Sites; Cholinesterase Inhibitors; Computer Simulation; Guinea Pigs; Heart Atria; In Vitro Techniques; Isoindoles; Myocardial Contraction; N-Methylscopolamine; Oxotremorine; Parasympatholytics; Phthalimides; Receptors, Muscarinic; Regression Analysis; Scopolamine Derivatives	1995
Muscarinic acetylcholine receptor subtypes mediating urinary bladder contractility and coupling to GTP binding proteins. The Journal of pharmacology and experimental therapeutics, 1995, Volume: 273, Issue:2 Topics: Animals; GTP-Binding Proteins; Humans; Muscarinic Agonists; Muscle Contraction; N-Methylscopolamine; Oxotremorine; Precipitin Tests; Radioligand Assay; Receptors, Muscarinic; Scopolamine Derivatives; Species Specificity; Urinary Bladder	1995
The muscarinic receptor agonist L-658,903 modulates the in vivo accumulation of inositol monophosphates in mouse brain. European journal of pharmacology, 1994, May-17, Volume: 267, Issue:3 Topics: Animals; Binding Sites; Brain; Dose-Response Relationship, Drug; In Vitro Techniques; Inositol Phosphates; Lithium Chloride; Male; Mice; N-Methylscopolamine; Oxadiazoles; Oxotremorine; Parasympatholytics; Pilocarpine; Quinuclidines; Receptors, Muscarinic; Scopolamine; Scopolamine Derivatives	1994
Sequestration of muscarinic cholinergic receptors in permeabilized neuroblastoma cells. Journal of neurochemistry, 1994, Volume: 62, Issue:5 Topics: Adenosine Triphosphate; Binding Sites; Calcium; Cell Line; Cell Membrane; Cell Membrane Permeability; Cytosol; Digitonin; Guanine Nucleotides; Humans; Kinetics; N-Methylscopolamine; Neuroblastoma; Oxotremorine; Phosphatidylinositols; Quinuclidinyl Benzilate; Receptors, Muscarinic; Scopolamine Derivatives; Tumor Cells, Cultured	1994
The synthesis and biochemical pharmacology of enantiomerically pure methylated oxotremorine derivatives. Journal of medicinal chemistry, 1993, Nov-12, Volume: 36, Issue:23 Topics: Animals; Binding, Competitive; Cerebral Cortex; Guanylyl Imidodiphosphate; Male; Methylation; N-Methylscopolamine; Oxotremorine; Pirenzepine; Quinuclidinyl Benzilate; Rats; Rats, Wistar; Receptors, Muscarinic; Scopolamine Derivatives; Stereoisomerism	1993
Studies of muscarinic receptor reserve linked to phosphoinositide hydrolysis in parotid gland and cerebral cortex. Acta physiologica Scandinavica, 1993, Volume: 147, Issue:3 Topics: Animals; Carbachol; Cerebral Cortex; Choline; Guinea Pigs; Hydrolysis; In Vitro Techniques; Kinetics; N-Methylscopolamine; Oxotremorine; Parasympathomimetics; Parotid Gland; Phosphatidylinositols; Pirenzepine; Receptors, Muscarinic; Scopolamine Derivatives	1993
Muscarinic M3 receptors mediate total inositol phosphates accumulation in murine HSDM1C1 fibrosarcoma cells. European journal of pharmacology, 1993, Jan-04, Volume: 244, Issue:1 Topics: Animals; Binding, Competitive; Carbachol; Dioxolanes; Fibrosarcoma; Inositol Phosphates; Mice; Muscarine; Muscarinic Antagonists; N-Methylscopolamine; Oxotremorine; Parasympatholytics; Parasympathomimetics; Pirenzepine; Radioligand Assay; Receptors, Muscarinic; Scopolamine Derivatives; Tumor Cells, Cultured	1993
Differences between rat dorsal and ventral hippocampus in muscarinic receptor agonist binding and interaction with phospholipase C. European journal of pharmacology, 1993, Jan-15, Volume: 244, Issue:2 Topics: Alkaloids; Animals; Carbachol; Furans; Guanylyl Imidodiphosphate; Hippocampus; Male; Membranes; Mitochondria; N-Methylscopolamine; Naphthalenes; Oxotremorine; Parasympatholytics; Parasympathomimetics; Phosphatidylinositols; Piperidines; Pirenzepine; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Scopolamine Derivatives; Synaptosomes; Type C Phospholipases	1993
Effects of some cholinergic agonists on neocortical slow wave activity in rats with basal forebrain lesions. Brain research bulletin, 1993, Volume: 31, Issue:5 Topics: Animals; Arecoline; Body Temperature; Brain; Cerebral Cortex; Dose-Response Relationship, Drug; Electroencephalography; Kainic Acid; Male; N-Methylscopolamine; Oxotremorine; Parasympatholytics; Parasympathomimetics; Pilocarpine; Prosencephalon; Rats; Scopolamine Derivatives; Tacrine	1993
Muscarinic cholinergic receptors in brain and atrial membranes of adult brook trout (Salvelinus fontinalis) measured by radioligand binding techniques. Comparative biochemistry and physiology. Part C, Pharmacology, toxicology & endocrinology, 1995, Volume: 112, Issue:1 Topics: Animals; Atropine; Binding, Competitive; Brain Chemistry; Carbachol; Heart Atria; Kinetics; Muscarinic Agonists; Muscarinic Antagonists; N-Methylscopolamine; Oxotremorine; Parasympatholytics; Pirenzepine; Radioligand Assay; Receptors, Muscarinic; Scopolamine; Scopolamine Derivatives; Trout	1995
Changes in rat brain muscarinic receptors after inhibitory avoidance learning. Life sciences, 1996, Volume: 58, Issue:9 Topics: Amygdala; Animals; Avoidance Learning; Brain; Cerebral Cortex; Discrimination, Psychological; Hippocampus; Kinetics; Male; Memory; N-Methylscopolamine; Neostriatum; Organ Specificity; Oxotremorine; Pirenzepine; Rats; Rats, Wistar; Receptors, Muscarinic; Reinforcement, Psychology; Scopolamine Derivatives	1996
Alanine scanning mutagenesis of conserved arginine/lysine-arginine/lysine-X-X-arginine/lysine G protein-activating motifs on m1 muscarinic acetylcholine receptors. Molecular pharmacology, 1996, Volume: 50, Issue:1 Topics: Alanine; Amino Acid Sequence; Animals; Base Sequence; Binding Sites; Binding, Competitive; Carbachol; Cell Membrane; CHO Cells; Conserved Sequence; Cricetinae; DNA Primers; GTP-Binding Proteins; Guanosine Triphosphate; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; N-Methylscopolamine; Oxotremorine; Protein Structure, Secondary; Quinuclidinyl Benzilate; Receptor, Muscarinic M2; Receptors, Muscarinic; Recombinant Proteins; Scopolamine Derivatives; Second Messenger Systems; Transfection	1996
Opposite effects of alcuronium on agonist and on antagonist binding to muscarinic receptors. European journal of pharmacology, 1996, Jun-03, Volume: 305, Issue:1-3 Topics: Alcuronium; Animals; Cell Membrane; In Vitro Techniques; Muscarinic Agonists; Muscarinic Antagonists; Myocardium; N-Methylscopolamine; Nicotinic Antagonists; Oxotremorine; Protein Binding; Receptors, Muscarinic; Scopolamine Derivatives; Swine	1996
Inhibition of antagonist and agonist binding to the human brain muscarinic receptor by arachidonic acid. Journal of molecular neuroscience : MN, 1998, Volume: 10, Issue:3 Topics: Adult; Arachidonic Acids; Chromans; Fatty Acids; Feedback; Frontal Lobe; Glutathione; Humans; Kinetics; Manganese; Muscarinic Agonists; Muscarinic Antagonists; N-Methylscopolamine; Oxotremorine; Palmitic Acid; Quinuclidinyl Benzilate; Receptors, Muscarinic	1998
Inhibition of GTPase activity of Gi proteins and decreased agonist affinity at M2 muscarinic acetylcholine receptors by spermine and methoctramine. British journal of pharmacology, 1999, Volume: 127, Issue:4 Topics: Animals; Diamines; GTP Phosphohydrolases; GTP-Binding Protein alpha Subunits, Gi-Go; Muscarinic Agonists; Muscarinic Antagonists; N-Methylscopolamine; Organ Specificity; Oxotremorine; Rats; Receptor, Muscarinic M2; Receptors, Muscarinic; Spermine; Swine	1999
Evaluation of an agonist index: affinity ratio for compounds active on muscarinic cholinergic M2 receptors. Journal of autonomic pharmacology, 1999, Volume: 19, Issue:2 Topics: Animals; Binding, Competitive; Cerebral Cortex; Guinea Pigs; Ileum; In Vitro Techniques; Isometric Contraction; Male; Muscle, Smooth; Myocardium; N-Methylscopolamine; Oxotremorine; Rabbits; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Submandibular Gland; Urinary Bladder; Vas Deferens; Visual Cortex	1999
Alanine-scanning mutagenesis of transmembrane domain 6 of the M(1) muscarinic acetylcholine receptor suggests that Tyr381 plays key roles in receptor function. Molecular pharmacology, 1999, Volume: 56, Issue:5 Topics: Acetylcholine; Alanine; Animals; Atropine; Binding, Competitive; COS Cells; Immunohistochemistry; Ligands; Muscarinic Agonists; Muscarinic Antagonists; Mutagenesis, Site-Directed; N-Methylscopolamine; Oxotremorine; Phosphatidylinositols; Pilocarpine; Protein Structure, Tertiary; Quinuclidinyl Benzilate; Rats; Receptor, Muscarinic M1; Receptors, Muscarinic; Tyrosine	1999
A G protein gamma subunit-specific peptide inhibits muscarinic receptor signaling. The Journal of biological chemistry, 1999, Dec-10, Volume: 274, Issue:50 Topics: Amino Acid Sequence; Animals; Brain; Calcium; Calcium Channels; Carbachol; Cattle; Cells, Cultured; CHO Cells; Clonidine; Cricetinae; Cytoplasm; Guanosine 5'-O-(3-Thiotriphosphate); Heterotrimeric GTP-Binding Proteins; In Vitro Techniques; N-Methylscopolamine; Neurons; Oxotremorine; Peptide Fragments; Receptor, Muscarinic M4; Receptors, Adrenergic, alpha-2; Receptors, Muscarinic; Receptors, Somatostatin; Signal Transduction; Spinal Cord; Superior Cervical Ganglion; Transfection	1999
Cloning and functional characterization of a Caenorhabditis elegans muscarinic acetylcholine receptor. Receptors & channels, 1999, Volume: 6, Issue:6 Topics: Acetylcholine; Amino Acid Sequence; Animals; Atropine; Base Sequence; Binding, Competitive; Caenorhabditis elegans; Chloride Channels; CHO Cells; Cloning, Molecular; Cricetinae; Gene Expression; Ion Channel Gating; Ligands; Molecular Sequence Data; N-Methylscopolamine; Oxotremorine; Receptors, Muscarinic; Recombinant Proteins; Scopolamine; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Xenopus	1999
Peripheral versus central muscarinic effects on blood pressure, cardiac contractility, heart rate, and body temperature in the rat monitored by radiotelemetry. Pharmacology & toxicology, 2001, Volume: 89, Issue:1 Topics: Animals; Blood Pressure; Body Temperature; Drug Interactions; Heart Rate; Male; Motor Activity; Muscarinic Agonists; Muscarinic Antagonists; Myocardial Contraction; N-Methylscopolamine; Oxotremorine; Parasympatholytics; Rats; Rats, Long-Evans; Telemetry	2001
Effects of N-ethylmaleimide on conformational equilibria in purified cardiac muscarinic receptors. The Journal of biological chemistry, 2002, Sep-27, Volume: 277, Issue:39 Topics: Animals; Blotting, Western; Carbachol; Cell Line; Enzyme Inhibitors; Ethylmaleimide; Humans; Insecta; Kinetics; Ligands; Models, Chemical; Muscarinic Agonists; N-Methylscopolamine; Oxotremorine; Parasympatholytics; Precipitin Tests; Protein Binding; Protein Conformation; Quinuclidinyl Benzilate; Receptor, Muscarinic M2; Receptors, Muscarinic; Sulfhydryl Reagents; Swine; Time Factors	2002
Comparison of the pharmacological antagonism of M2 and M3 muscarinic receptors expressed in isolation and in combination. Biochemical pharmacology, 2003, Apr-15, Volume: 65, Issue:8 Topics: Animals; CHO Cells; Cricetinae; Cyclic AMP; Humans; Kinetics; Muscarinic Antagonists; N-Methylscopolamine; Oxotremorine; Phosphatidylinositols; Pirenzepine; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Receptors, Muscarinic; Recombinant Proteins; Transfection	2003
Allosteric site in M2 acetylcholine receptors: evidence for a major conformational change upon binding of an orthosteric agonist instead of an antagonist. Naunyn-Schmiedeberg's archives of pharmacology, 2006, Volume: 372, Issue:4 Topics: Allosteric Regulation; Allosteric Site; Animals; Binding, Competitive; Gallamine Triethiodide; In Vitro Techniques; Isoindoles; Muscarinic Agonists; Muscarinic Antagonists; Myocardium; N-Methylscopolamine; Obidoxime Chloride; Oxotremorine; Phthalimides; Protein Conformation; Pyridinium Compounds; Receptor, Muscarinic M2; Swine	2006
Function-specific blockage of M(1) and M(3) muscarinic acetylcholine receptors by VX and echothiophate. Brain research, 2006, Apr-26, Volume: 1085, Issue:1 Topics: Animals; Atropine; CHO Cells; Cholinesterase Inhibitors; Colforsin; Cricetinae; Cyclic AMP; Dose-Response Relationship, Drug; Drug Interactions; Echothiophate Iodide; Muscarinic Agonists; Muscarinic Antagonists; N-Methylscopolamine; Organothiophosphorus Compounds; Oxotremorine; Phosphatidylinositols; Protein Binding; Receptor, Muscarinic M1; Receptor, Muscarinic M3; Transfection; Tritium	2006
Recovery of oligomers and cooperativity when monomers of the M2 muscarinic cholinergic receptor are reconstituted into phospholipid vesicles. Biochemistry, 2007, Jul-03, Volume: 46, Issue:26 Topics: Animals; Guanylyl Imidodiphosphate; Humans; Ligands; Liposomes; N-Methylscopolamine; Oxotremorine; Phospholipids; Protein Structure, Quaternary; Quinuclidinyl Benzilate; Receptor, Muscarinic M2; Spodoptera	2007
Oxotremorine-induced hypothermia as a method for evaluating long-term neuronal changes following poisoning by cholinesterase inhibitors in rats. Toxicology, 2007, Dec-05, Volume: 242, Issue:1-3 Topics: Aldicarb; Animals; Body Temperature; Carbamates; Central Nervous System; Cholinesterase Inhibitors; Disease Models, Animal; Hypothermia; Lethal Dose 50; Male; Muscarinic Agonists; Muscarinic Antagonists; N-Methylscopolamine; Organophosphorus Compounds; Organothiophosphorus Compounds; Oxotremorine; Peripheral Nervous System; Rats; Rats, Sprague-Dawley; Recovery of Function; Reproducibility of Results; Sarin; Seizures; Time Factors; Toxicity Tests	2007
Nucleus accumbens acetylcholine and food intake: decreased muscarinic tone reduces feeding but not food-seeking. Behavioural brain research, 2009, Mar-02, Volume: 198, Issue:1 Topics: Acetylcholine; Animals; Dose-Response Relationship, Drug; Eating; Feeding Behavior; Male; Microinjections; Muscarinic Agonists; Muscarinic Antagonists; N-Methylscopolamine; Nucleus Accumbens; Oxotremorine; Parasympatholytics; Pirenzepine; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic	2009
Exploring the mechanism of agonist efficacy: a relationship between efficacy and agonist dissociation rate at the muscarinic M3 receptor. Molecular pharmacology, 2009, Volume: 76, Issue:3 Topics: Acetylcholine; Animals; Binding, Competitive; CHO Cells; Cricetinae; Cricetulus; Humans; Kinetics; Models, Biological; Muscarinic Agonists; N-Methylscopolamine; Oxotremorine; Receptor, Muscarinic M3	2009