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n-methylscopolamine and guanosine triphosphate

n-methylscopolamine has been researched along with guanosine triphosphate in 14 studies

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19909 (64.29)18.7374
1990's5 (35.71)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ehlert, FJ; Rathbun, BE1
Jagadeesh, G; Phan, NT; Rao, TS; Sulakhe, PV; Veeranjaneyulu, A1
Ellis, J; Hoss, W1
Brunner, F; Christophe, J; Gillard, M; Svoboda, M; Waelbroeck, M1
Ek, B; Nahorski, S1
Ehlert, FJ3
Harden, TK; Petch, LA; Traynelis, SF; Waldo, GL1
Hammer, R1
Dziekan, LC; Galper, JB; O'Hara, DS; Smith, TW1
Ehlert, FJ; Thomas, EA1
Cheng, E; Cline, RT; Fraser, CM; Geoghagen, NS; Lee, NH1
Birdsall, B; Birdsall, NJ; Fukazawa, T; Gharagozloo, P; Hashimoto, T; Kuwano, H; Lazareno, S; Popham, A; Sugimoto, M1

Reviews

1 review(s) available for n-methylscopolamine and guanosine triphosphate

ArticleYear
Muscarinic receptor subtypes in the central nervous system.
    International review of neurobiology, 1985, Volume: 26

    Topics: Adenylyl Cyclases; Affinity Labels; Animals; Brain; Brain Chemistry; Copper; Disulfides; Gallamine Triethiodide; Guanosine Triphosphate; Guanylate Cyclase; Hormones; Ion Channels; Male; Metals; N-Methylscopolamine; Phosphatidylinositols; Phosphorylation; Quinuclidinyl Benzilate; Radioligand Assay; Rats; Receptors, Muscarinic; Scopolamine Derivatives; Sulfhydryl Compounds

1985

Other Studies

13 other study(ies) available for n-methylscopolamine and guanosine triphosphate

ArticleYear
Signaling through the muscarinic receptor-adenylate cyclase system of the heart is buffered against GTP over a range of concentrations.
    Molecular pharmacology, 1990, Volume: 38, Issue:1

    Topics: Adenylyl Cyclase Inhibitors; Animals; Carbachol; Guanosine Triphosphate; Male; Myocardium; N-Methylscopolamine; Oxotremorine; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Scopolamine Derivatives

1990
MgCl2-sensitive and Gpp(NH)p-sensitive antagonist binding states of rat heart muscarinic receptors: preferential detection at ambient temperature assay and location in two subcellular fractions.
    Molecular and cellular biochemistry, 1990, May-10, Volume: 94, Issue:2

    Topics: Animals; Dithiothreitol; Ethylmaleimide; Guanine Nucleotides; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Kinetics; Magnesium Chloride; Male; Microsomes; Myocardium; N-Methylscopolamine; Quinuclidinyl Benzilate; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Scopolamine Derivatives; Temperature

1990
Bretylium tosylate binds preferentially to muscarinic receptors labelled with [3H]oxotremorine M (SH or 'high affinity' receptors) in rat heart and brain cortex.
    European journal of pharmacology, 1989, Jan-24, Volume: 160, Issue:1

    Topics: Animals; Bretylium Compounds; Bretylium Tosylate; Cerebral Cortex; Guanosine Triphosphate; Heart; In Vitro Techniques; Male; Membranes; Myocardium; N-Methylscopolamine; Oxotremorine; Pilocarpine; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Scopolamine Derivatives

1989
Muscarinic receptor coupling to inositol phospholipid metabolism in guinea-pig cerebral cortex, parotid gland and ileal smooth muscle.
    Biochemical pharmacology, 1988, Dec-01, Volume: 37, Issue:23

    Topics: Animals; Atropine; Carbachol; Cerebral Cortex; Guanosine Triphosphate; Guinea Pigs; Ileum; Muscle, Smooth; N-Methylscopolamine; Oxotremorine; Parotid Gland; Phosphatidylinositols; Pirenzepine; Receptors, Muscarinic; Scopolamine Derivatives

1988
Effects of an alkylating derivative of oxotremorine (BM 123A) on heart rate, muscarinic receptors and adenylate cyclase activity in the rabbit myocardium.
    The Journal of pharmacology and experimental therapeutics, 1987, Volume: 241, Issue:3

    Topics: Adenylyl Cyclases; Animals; Aziridines; Azirines; Guanosine Triphosphate; Heart Rate; Male; Mathematics; Myocardium; N-Methylscopolamine; Oxotremorine; Pyrrolidinones; Rabbits; Receptors, Muscarinic; Scopolamine Derivatives

1987
Coupling of muscarinic receptors to adenylate cyclase in the rabbit myocardium: effects of receptor inactivation.
    The Journal of pharmacology and experimental therapeutics, 1987, Volume: 240, Issue:1

    Topics: Adenylyl Cyclases; Alkylation; Animals; Binding, Competitive; Choline; Dithiothreitol; Dose-Response Relationship, Drug; Guanosine Triphosphate; Kinetics; Male; Mathematics; Myocardium; N-Methylscopolamine; Oxotremorine; Quinuclidinyl Benzilate; Rabbits; Receptors, Muscarinic; Scopolamine Derivatives

1987
Agonist-induced alteration in the membrane form of muscarinic cholinergic receptors.
    The Journal of biological chemistry, 1985, Oct-25, Volume: 260, Issue:24

    Topics: Astrocytoma; Atropine; Carbachol; Cell Fractionation; Cell Line; Cell Membrane; Centrifugation, Density Gradient; Guanosine Triphosphate; Humans; Kinetics; N-Methylscopolamine; Quinuclidinyl Benzilate; Receptors, Muscarinic; Scopolamine Derivatives

1985
The relationship between muscarinic receptor occupancy and adenylate cyclase inhibition in the rabbit myocardium.
    Molecular pharmacology, 1985, Volume: 28, Issue:5

    Topics: Adenylyl Cyclase Inhibitors; Animals; Carbachol; Guanosine Triphosphate; In Vitro Techniques; Male; Models, Structural; Myocardium; N-Methylscopolamine; Oxotremorine; Rabbits; Receptors, Muscarinic; Scopolamine Derivatives; Tritium

1985
Muscarinic receptors in the stomach.
    Scandinavian journal of gastroenterology. Supplement, 1980, Volume: 66

    Topics: Animals; Benzodiazepinones; Carbachol; Dogs; Gastric Fundus; Gastric Mucosa; Guanosine Triphosphate; Muscarinic Antagonists; Muscle, Smooth; N-Methylscopolamine; Piperazines; Pirenzepine; Receptors, Cholinergic; Receptors, Muscarinic; Scopolamine Derivatives; Sympathetic Nervous System

1980
The biphasic response of muscarinic cholinergic receptors in cultured heart cells to agonists. Effects on receptor number and affinity in intact cells and homogenates.
    The Journal of biological chemistry, 1982, Sep-10, Volume: 257, Issue:17

    Topics: Animals; Carbachol; Cell Membrane; Cells, Cultured; Chick Embryo; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Kinetics; Myocardium; N-Methylscopolamine; Quinuclidines; Quinuclidinyl Benzilate; Receptors, Cholinergic; Receptors, Muscarinic; Scopolamine Derivatives

1982
Pertussis toxin blocks M2 muscarinic receptor-mediated effects on contraction and cyclic AMP in the guinea pig ileum, but not M3-mediated contractions and phosphoinositide hydrolysis.
    The Journal of pharmacology and experimental therapeutics, 1994, Volume: 271, Issue:2

    Topics: Adenosine Diphosphate Ribose; Adenylate Cyclase Toxin; Animals; Cyclic AMP; Guanosine Triphosphate; Guinea Pigs; Hydrolysis; Ileum; In Vitro Techniques; Isoproterenol; Male; Muscle Contraction; N-Methylscopolamine; Pertussis Toxin; Phosphatidylinositols; Pirenzepine; Receptors, Muscarinic; Scopolamine Derivatives; Signal Transduction; Virulence Factors, Bordetella

1994
Alanine scanning mutagenesis of conserved arginine/lysine-arginine/lysine-X-X-arginine/lysine G protein-activating motifs on m1 muscarinic acetylcholine receptors.
    Molecular pharmacology, 1996, Volume: 50, Issue:1

    Topics: Alanine; Amino Acid Sequence; Animals; Base Sequence; Binding Sites; Binding, Competitive; Carbachol; Cell Membrane; CHO Cells; Conserved Sequence; Cricetinae; DNA Primers; GTP-Binding Proteins; Guanosine Triphosphate; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; N-Methylscopolamine; Oxotremorine; Protein Structure, Secondary; Quinuclidinyl Benzilate; Receptor, Muscarinic M2; Receptors, Muscarinic; Recombinant Proteins; Scopolamine Derivatives; Second Messenger Systems; Transfection

1996
Allosteric effects of four stereoisomers of a fused indole ring system with 3H-N-methylscopolamine and acetylcholine at M1-M4 muscarinic receptors.
    Life sciences, 1999, Volume: 64, Issue:6-7

    Topics: Acetylcholine; Allosteric Regulation; Allosteric Site; Animals; Cell Membrane; CHO Cells; Cricetinae; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Humans; Indoles; Kinetics; Muscarinic Agonists; Muscarinic Antagonists; N-Methylscopolamine; Propylbenzilylcholine Mustard; Receptors, Muscarinic; Stereoisomerism; Strychnine; Thermodynamics

1999