n-methylscopolamine has been researched along with guanosine 5'-o-(3-thiotriphosphate) in 25 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 12 (48.00) | 18.2507 |
| 2000's | 9 (36.00) | 29.6817 |
| 2010's | 4 (16.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bali, JP; Cros, G; Serrano, JJ; Soulié, ML | 1 |
| Jakobs, KH; Liebmann, C; Nawrath, S; Schnittler, M; Schubert, H | 1 |
| Haga, T; Rinken, A | 1 |
| Olianas, MC; Onali, P | 2 |
| Challiss, RA; Nahorski, SR; Stuart, JA; Willars, GB | 1 |
| Chidiac, P; Green, MA; Wells, JW | 1 |
| Maullu, C; Olianas, MC; Onali, P | 2 |
| Adem, A; Ingianni, A; Karlsson, E; Maullu, C; Olianas, MC; Onali, P | 1 |
| Birdsall, B; Birdsall, NJ; Fukazawa, T; Gharagozloo, P; Hashimoto, T; Kuwano, H; Lazareno, S; Popham, A; Sugimoto, M | 1 |
| Azpiazu, I; Cruzblanca, H; Gautam, N; Li, P; Linder, M; Zhuo, M | 1 |
| Adem, A; Karlsson, E; Maullu, C; Mulugeta, E; Olianas, MC; Onali, P | 1 |
| Corsini, GU; Maggio, R; Novi, F; Scarselli, M | 1 |
| Doi, Y; Kaibara, M; Mitarai, S; Murasaki, O; Nagase, Y; Sumikawa, K; Taniyama, K | 1 |
| Adem, A; Karlsson, E; Olianas, MC; Onali, P | 1 |
| Dolezal, V; El-Fakahany, EE; Jakubík, J | 1 |
| Dolezal, V; Iivonen, H; Jakubík, J; Machová, E; Michal, P; Oksman, M; Tanila, H | 1 |
| Challiss, RA; Langmead, CJ; Mistry, R; Thomas, RL; Wood, MD | 1 |
| Dolezal, V; Jakubik, J; Karlsson, E; Mordvintsev, DY; Polyak, YL; Rodionov, DI; Tsetlin, VI; Utkin, YN | 1 |
| Christopoulos, A; Felder, CC; Leach, K; Loiacono, RE; McKinzie, DL; Mogg, A; Sexton, PM; Shaw, DB | 1 |
| Dolezal, V; El-Fakahany, EE; Jakubík, J; Randáková, A | 1 |
| Doležal, V; El-Fakahany, EE; Jakubík, J; Janíčková, H | 1 |
| Doležal, V; El-Fakahany, EE; Jakubík, J; Janíčková, H; Randáková, A | 1 |
| Dolejší, E; Doležal, V; Liraz, O; Michaelson, DM; Rudajev, V; Zimčík, P | 1 |
25 other study(ies) available for n-methylscopolamine and guanosine 5'-o-(3-thiotriphosphate)
| Article | Year |
|---|---|
Impairment of contractile response to carbachol and muscarinic receptor coupling in gastric antral smooth muscle cells isolated from diabetic streptozotocin-treated rats and db/db mice.
Topics: Animals; Carbachol; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Disease Models, Animal; Erythromycin; Female; Guanosine 5'-O-(3-Thiotriphosphate); Insulin; Male; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Muscle Contraction; Muscle, Smooth; N-Methylscopolamine; Pyloric Antrum; Rats; Receptors, Muscarinic; Scopolamine Derivatives; Streptozocin | 1992 |
Binding characteristics and functional G protein coupling of muscarinic acetylcholine receptors in rat duodenum smooth muscle membranes.
Topics: Animals; Binding Sites; Binding, Competitive; Cell Membrane; Cerebral Cortex; Duodenum; Female; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Kinetics; Male; Muscle, Smooth; Myocardium; N-Methylscopolamine; Oxotremorine; Parasympatholytics; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Scopolamine Derivatives; Submandibular Gland | 1992 |
Solubilization and characterization of atrial muscarinic acetylcholine receptors in sucrose monolaurate.
Topics: Animals; Cell Membrane; Centrifugation, Density Gradient; Drug Stability; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Half-Life; Heart Atria; Myocardium; N-Methylscopolamine; Quinuclidinyl Benzilate; Receptors, Muscarinic; Scopolamine Derivatives; Solubility; Sucrose; Swine; Temperature; Thermodynamics | 1993 |
Characterization of the G protein involved in the muscarinic stimulation of adenylyl cyclase of rat olfactory bulb.
Topics: Adenosine Diphosphate Ribose; Adenylyl Cyclases; Animals; Binding, Competitive; Carbachol; Cholera Toxin; Enzyme Activation; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Immune Sera; Male; Muscarinic Agonists; N-Methylscopolamine; Neuropeptides; Olfactory Bulb; Pituitary Adenylate Cyclase-Activating Polypeptide; Rats; Rats, Sprague-Dawley; Scopolamine Derivatives; Tritium | 1996 |
Contrasting effects of phorbol ester and agonist-mediated activation of protein kinase C on phosphoinositide and Ca2+ signalling in a human neuroblastoma.
Topics: Animals; Calcium; Calcium-Transporting ATPases; Carbachol; Cell Line; CHO Cells; Cricetinae; Cytosol; Enzyme Activation; Enzyme Inhibitors; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Inositol 1,4,5-Trisphosphate; Isoenzymes; Kinetics; Lithium; N-Methylscopolamine; Neuroblastoma; Phorbol 12,13-Dibutyrate; Phosphatidylinositols; Protein Kinase C; Receptor, Muscarinic M3; Receptors, Muscarinic; Recombinant Proteins; Scopolamine Derivatives; Signal Transduction; Terpenes; Thapsigargin; Transfection; Tumor Cells, Cultured | 1996 |
Cardiac muscarinic receptors. Relationship between the G protein and multiple states of affinity.
Topics: Animals; Carbachol; Cell Membrane; Cricetinae; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanylyl Imidodiphosphate; Mesocricetus; Muscarinic Antagonists; Myocardium; N-Methylscopolamine; Osmolar Concentration; Parasympatholytics; Propylbenzilylcholine Mustard; Receptors, Muscarinic; Scopolamine Derivatives; Tritium | 1997 |
Impairment of muscarinic stimulation of adenylyl cyclase by heparin in rat olfactory bulb.
Topics: Adenylyl Cyclases; Animals; Carbachol; Colforsin; Corpus Striatum; Enzyme Activation; GTP-Binding Protein alpha Subunits, Gs; Guanosine 5'-O-(3-Thiotriphosphate); Heparin; In Vitro Techniques; Kinetics; Male; Muscarinic Agonists; N-Methylscopolamine; Olfactory Bulb; Parasympatholytics; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Scopolamine Derivatives | 1997 |
Effects of clozapine on rat striatal muscarinic receptors coupled to inhibition of adenylyl cyclase activity and on the human cloned m4 receptor.
Topics: Adenylyl Cyclases; Alkylation; Animals; Cell Membrane; CHO Cells; Clozapine; Colforsin; Corpus Striatum; Cricetinae; Cyclic AMP; Guanosine 5'-O-(3-Thiotriphosphate); Humans; In Vitro Techniques; Male; Muscarinic Antagonists; N-Methylscopolamine; Protein Binding; Quinolines; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Synaptosomes | 1997 |
Selectivity profile of muscarinic toxin 3 in functional assays of cloned and native receptors.
Topics: Adenylyl Cyclases; Animals; Cell Membrane; CHO Cells; Cricetinae; Gene Expression; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Intercellular Signaling Peptides and Proteins; Metallothionein 3; Mice; Muscarinic Antagonists; N-Methylscopolamine; Peptides; Receptor, Muscarinic M1; Receptor, Muscarinic M2; Receptor, Muscarinic M4; Receptors, Muscarinic; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; Sulfur Radioisotopes; Tritium; Tumor Cells, Cultured | 1999 |
Mixed agonist-antagonist properties of clozapine at different human cloned muscarinic receptor subtypes expressed in Chinese hamster ovary cells.
Topics: Animals; Antipsychotic Agents; Atropine; Binding Sites; Cell Membrane; CHO Cells; Cloning, Molecular; Clozapine; Cricetinae; Cyclic AMP; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Inositol Phosphates; Muscarinic Agonists; Muscarinic Antagonists; N-Methylscopolamine; Receptor, Muscarinic M1; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Receptors, Muscarinic; Sulfur Radioisotopes | 1999 |
Allosteric effects of four stereoisomers of a fused indole ring system with 3H-N-methylscopolamine and acetylcholine at M1-M4 muscarinic receptors.
Topics: Acetylcholine; Allosteric Regulation; Allosteric Site; Animals; Cell Membrane; CHO Cells; Cricetinae; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Humans; Indoles; Kinetics; Muscarinic Agonists; Muscarinic Antagonists; N-Methylscopolamine; Propylbenzilylcholine Mustard; Receptors, Muscarinic; Stereoisomerism; Strychnine; Thermodynamics | 1999 |
A G protein gamma subunit-specific peptide inhibits muscarinic receptor signaling.
Topics: Amino Acid Sequence; Animals; Brain; Calcium; Calcium Channels; Carbachol; Cattle; Cells, Cultured; CHO Cells; Clonidine; Cricetinae; Cytoplasm; Guanosine 5'-O-(3-Thiotriphosphate); Heterotrimeric GTP-Binding Proteins; In Vitro Techniques; N-Methylscopolamine; Neurons; Oxotremorine; Peptide Fragments; Receptor, Muscarinic M4; Receptors, Adrenergic, alpha-2; Receptors, Muscarinic; Receptors, Somatostatin; Signal Transduction; Spinal Cord; Superior Cervical Ganglion; Transfection | 1999 |
Inhibition of acetylcholine muscarinic M(1) receptor function by the M(1)-selective ligand muscarinic toxin 7 (MT-7).
Topics: Acetylcholine; Animals; Carbachol; Cell Membrane; CHO Cells; Cholinergic Agents; Cricetinae; Cyclic AMP; Elapid Venoms; Guanosine 5'-O-(3-Thiotriphosphate); Inositol Phosphates; Muscarinic Antagonists; N-Methylscopolamine; Receptor, Muscarinic M1; Receptors, Muscarinic; Tritium | 2000 |
An unusual form of the association binding kinetics of N-[3H]methylscopolamine to the split muscarinic M2trunk/M2tail receptor.
Topics: Adenylyl Cyclases; Animals; Cell Membrane; Cells, Cultured; Chlorocebus aethiops; COS Cells; Gallamine Triethiodide; Guanosine 5'-O-(3-Thiotriphosphate); Indicators and Reagents; Kinetics; Muscarinic Antagonists; N-Methylscopolamine; Nicotinic Antagonists; Parasympatholytics; Peptide Fragments; Plasmids; Quinuclidinyl Benzilate; Receptor, Muscarinic M2; Receptors, Muscarinic | 2003 |
Site of action of the general anesthetic propofol in muscarinic M1 receptor-mediated signal transduction.
Topics: Acetylcholine; Anesthetics, Intravenous; Animals; Cystic Fibrosis Transmembrane Conductance Regulator; DNA, Complementary; Electrophysiology; G Protein-Coupled Inwardly-Rectifying Potassium Channels; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Protein alpha Subunits, Gs; Guanosine 5'-O-(3-Thiotriphosphate); Humans; N-Methylscopolamine; Oocytes; Parasympatholytics; Patch-Clamp Techniques; Potassium Channels; Potassium Channels, Inwardly Rectifying; Propofol; Radioligand Assay; Rats; Receptor, Muscarinic M1; Receptor, Muscarinic M2; Signal Transduction; Xenopus laevis | 2003 |
Action of the muscarinic toxin MT7 on agonist-bound muscarinic M1 receptors.
Topics: Acetylcholine; Animals; Cell Membrane; CHO Cells; Cholinergic Agents; Cloning, Molecular; Cricetinae; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Inositol Phosphates; Muscarinic Agonists; N-Methylscopolamine; Parasympatholytics; Receptor, Muscarinic M1 | 2004 |
Differences in kinetics of xanomeline binding and selectivity of activation of G proteins at M(1) and M(2) muscarinic acetylcholine receptors.
Topics: Animals; Carbachol; CHO Cells; Cricetinae; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Kinetics; Muscarinic Agonists; N-Methylscopolamine; Pyridines; Receptor, Muscarinic M1; Receptor, Muscarinic M2; Thiadiazoles | 2006 |
Impairment of muscarinic transmission in transgenic APPswe/PS1dE9 mice.
Topics: Acetylcholinesterase; Age Factors; Amyloid beta-Protein Precursor; Analysis of Variance; Animals; Animals, Genetically Modified; Dose-Response Relationship, Drug; Female; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Mice; Mutation; N-Methylscopolamine; Piperidines; Presenilin-1; Protein Binding; Receptors, Muscarinic; Synaptic Transmission; Vesicular Acetylcholine Transport Proteins | 2008 |
G protein coupling and signaling pathway activation by m1 muscarinic acetylcholine receptor orthosteric and allosteric agonists.
Topics: Animals; CHO Cells; Cricetinae; Cricetulus; Cyclic AMP; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Protein alpha Subunits, Gq-G11; GTP-Binding Protein alpha Subunits, Gs; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Inositol 1,4,5-Trisphosphate; Muscarinic Agonists; N-Methylscopolamine; Piperidines; Quinolones; Receptor, Muscarinic M1; Signal Transduction | 2008 |
Weak toxin WTX from Naja kaouthia cobra venom interacts with both nicotinic and muscarinic acetylcholine receptors.
Topics: Acetylcholine; Adrenal Glands; Animals; CHO Cells; Cricetinae; Cricetulus; Elapid Venoms; Female; Guanosine 5'-O-(3-Thiotriphosphate); Male; Mice; N-Methylscopolamine; Rats; Rats, Wistar; Receptors, Muscarinic; Receptors, Nicotinic | 2009 |
Molecular mechanisms of action and in vivo validation of an M4 muscarinic acetylcholine receptor allosteric modulator with potential antipsychotic properties.
Topics: Acetylcholine; Allosteric Regulation; Allosteric Site; Animals; Antipsychotic Agents; Avoidance Learning; Binding, Competitive; Cell Line; Corpus Striatum; Cricetinae; Cricetulus; Dose-Response Relationship, Drug; Guanosine 5'-O-(3-Thiotriphosphate); In Vitro Techniques; Mice; Mice, Knockout; Models, Molecular; Multivariate Analysis; Muscarinic Antagonists; N-Methylscopolamine; Nicotinic Acids; Parasympatholytics; Phosphorylation; Protein Transport; Quinuclidinyl Benzilate; Radioligand Assay; Rats; Receptor, Muscarinic M4; Signal Transduction; Thiophenes; Tritium | 2010 |
Divergence of allosteric effects of rapacuronium on binding and function of muscarinic receptors.
Topics: Acetylcholine; Allosteric Regulation; Allosteric Site; Animals; Binding, Competitive; CHO Cells; Cricetinae; Cricetulus; Female; Guanosine 5'-O-(3-Thiotriphosphate); Muscarinic Agonists; N-Methylscopolamine; Neuromuscular Nondepolarizing Agents; Radioligand Assay; Receptors, Muscarinic; Vecuronium Bromide | 2009 |
Negative cooperativity in binding of muscarinic receptor agonists and GDP as a measure of agonist efficacy.
Topics: Allosteric Regulation; Animals; CHO Cells; Cricetinae; Cricetulus; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Humans; Kinetics; Muscarinic Agonists; Muscarinic Antagonists; N-Methylscopolamine; Protein Binding; Radioligand Assay; Receptor, Muscarinic M2; Recombinant Proteins; Transfection | 2011 |
Subtype differences in pre-coupling of muscarinic acetylcholine receptors.
Topics: Animals; Binding, Competitive; Carbachol; CHO Cells; Cricetinae; Cricetulus; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Kinetics; Mutation; N-Methylscopolamine; Receptors, Muscarinic | 2011 |
Apolipoprotein E4 reduces evoked hippocampal acetylcholine release in adult mice.
Topics: Acetylcholine; Age Factors; Animals; Apolipoprotein E3; Apolipoprotein E4; Choline O-Acetyltransferase; Guanosine 5'-O-(3-Thiotriphosphate); Hippocampus; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; N-Methylscopolamine; Receptors, Muscarinic; Tritium; Vesicular Acetylcholine Transport Proteins | 2016 |