Page last updated: 2024-08-25

n-methylscopolamine and brucine

n-methylscopolamine has been researched along with brucine in 7 studies

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (57.14)18.2507
2000's2 (28.57)29.6817
2010's1 (14.29)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bacáková, L; El-Fakahany, EE; Jakubík, J; Tucek, S1
Bonnet, D; Daval, SB; Galzi, JL; Hibert, M; Ilien, B; Kellenberger, E; Valant, C1
Birdsall, NJ; Gharagozloo, P; Kuonen, D; Lazareno, S; Popham, A1
Birdsall, NJ; Gharagozloo, P; Lazareno, S; Popham, A1
Birdsall, B; Birdsall, NJ; Fukazawa, T; Gharagozloo, P; Hashimoto, T; Kuwano, H; Lazareno, S; Popham, A; Sugimoto, M1
Havlas, Z; Lysíková, M; Tucek, S1
Buller, S; Holzgrabe, U; Mohr, K; Zlotos, DP1

Other Studies

7 other study(ies) available for n-methylscopolamine and brucine

ArticleYear
Positive cooperativity of acetylcholine and other agonists with allosteric ligands on muscarinic acetylcholine receptors.
    Molecular pharmacology, 1997, Volume: 52, Issue:1

    Topics: Acetylcholine; Allosteric Regulation; Animals; Binding, Competitive; CHO Cells; Cricetinae; Ligands; Muscarinic Agonists; N-Methylscopolamine; Receptors, Muscarinic; Scopolamine Derivatives

1997
Fluorescent derivatives of AC-42 to probe bitopic orthosteric/allosteric binding mechanisms on muscarinic M1 receptors.
    Journal of medicinal chemistry, 2012, Mar-08, Volume: 55, Issue:5

    Topics: Allosteric Regulation; Calcium; Fluorescence Resonance Energy Transfer; Fluorescent Dyes; Green Fluorescent Proteins; HEK293 Cells; Humans; Models, Molecular; Molecular Probes; Piperidines; Radioligand Assay; Receptor, Muscarinic M1; Recombinant Fusion Proteins; Rhodamines; Solubility; Structure-Activity Relationship

2012
Subtype-selective positive cooperative interactions between brucine analogues and acetylcholine at muscarinic receptors: radioligand binding studies.
    Molecular pharmacology, 1998, Volume: 53, Issue:3

    Topics: Acetylcholine; Allosteric Regulation; Animals; CHO Cells; Cricetinae; N-Methylscopolamine; Radioligand Assay; Receptors, Muscarinic; Strychnine

1998
Allosteric interactions of quaternary strychnine and brucine derivatives with muscarinic acetylcholine receptors.
    Journal of medicinal chemistry, 1999, Feb-11, Volume: 42, Issue:3

    Topics: Allosteric Regulation; Animals; CHO Cells; Cricetinae; Humans; Muscarinic Antagonists; N-Methylscopolamine; Receptors, Muscarinic; Structure-Activity Relationship; Strychnine

1999
Allosteric effects of four stereoisomers of a fused indole ring system with 3H-N-methylscopolamine and acetylcholine at M1-M4 muscarinic receptors.
    Life sciences, 1999, Volume: 64, Issue:6-7

    Topics: Acetylcholine; Allosteric Regulation; Allosteric Site; Animals; Cell Membrane; CHO Cells; Cricetinae; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Humans; Indoles; Kinetics; Muscarinic Agonists; Muscarinic Antagonists; N-Methylscopolamine; Propylbenzilylcholine Mustard; Receptors, Muscarinic; Stereoisomerism; Strychnine; Thermodynamics

1999
Interactions between allosteric modulators and 4-DAMP and other antagonists at muscarinic receptors: potential significance of the distance between the N and carboxyl C atoms in the molecules of antagonists.
    Neurochemical research, 2001, Volume: 26, Issue:4

    Topics: Alcuronium; Allosteric Regulation; Animals; CHO Cells; Cricetinae; Muscarinic Antagonists; N-Methylscopolamine; Piperidines; Radioligand Assay; Strychnine; Tritium

2001
Bisquaternary dimers of strychnine and brucine. A new class of potent enhancers of antagonist binding to muscarinic M2 receptors.
    Bioorganic & medicinal chemistry, 2003, Jun-12, Volume: 11, Issue:12

    Topics: Allosteric Regulation; Animals; Dimerization; Molecular Conformation; Muscarinic Antagonists; N-Methylscopolamine; Radioligand Assay; Receptor, Muscarinic M2; Structure-Activity Relationship; Strychnine; Swine

2003