Page last updated: 2024-08-25

n-methylscopolamine and atropine

n-methylscopolamine has been researched along with atropine in 116 studies

Research

Studies (116)

Timeframe	Studies, this research(%)	All Research%
pre-1990	51 (43.97)	18.7374
1990's	37 (31.90)	18.2507
2000's	19 (16.38)	29.6817
2010's	8 (6.90)	24.3611
2020's	1 (0.86)	2.80

Authors

Authors	Studies
Christopoulos, A; El-Fakahany, EE; Pierce, TL; Sorman, JL	1
Go, ML; Sim, MK; Xu, R	1
Aoki, I; Fujikawa, T; Hasegawa, T; Hirose, H; Kimura, T; Mase, T; Mitsuya, M; Nishikibe, M; Noguchi, K; Numazawa, T; Ohtake, N; Sasaki, K; Sato, A	1
Bodor, N; Browne, CE; Buchwald, P; Farag, HH; Hochhaus, G; Huang, F; Ji, F; Wu, WM	1
Chen, Y; Cheng, K; Kennedy, RH; Khurana, S; Raufman, JP; Zimniak, P	1
Fruchart-Gaillard, C; Marquer, C; Ménez, A; Mourier, G; Servent, D	1
Charlton, SJ; Dowling, MR	1
Bloodworth, LM; Hamdan, FF; Han, SJ; Jacobson, KA; Kim, SK; Li, JH; Wess, J; Zhang, X	1
Bonnet, D; Daval, SB; Galzi, JL; Hibert, M; Ilien, B; Kellenberger, E; Valant, C	1
Bernhardt, G; Gmeiner, P; Hübner, H; Keller, M; Pegoli, A; She, X; Wifling, D	1
Bernhardt, G; Carpenter, J; Chen, M; Gmeiner, P; Gruber, CG; Holliday, ND; Hübner, H; Keller, M; Pegoli, A; She, X; Wan, J; Wifling, D	1
Ally, A; Hara, Y; Murayama, S	1
Akerman, KE; Kukkonen, J	1
Kajimura, M; Reuben, MA; Sachs, G	1
Shainberg, A; Waisberg, M	1
Bellido, I; Garcia, AJ; Gómez, A; Marquez, E; Martos, F; Pavia, J; Sanchez de la Cuesta, F	1
Vanderwolf, CH	1
Musílková, J; Shelkovnikov, SA; Starshinova, LA; Tucek, S	1
Yang, CM	1
Lambert, DG; Nahorski, SR; Wojcikiewicz, RJ	1
Bartfai, T; Grabczewska, E; Maslinski, W; Ryzewski, J	1
Haga, T; Honda, N; Ichiyama, A; Kajimura, M; Kaneko, E	1
Alonso, R; Didier, M; Soubrie, P	1
el-Fakahany, EE; Lee, NH	2
Chiang, PK; Covington, J; Jackson, BW; Leader, H; Newman, AH; Oleshansky, M; Weissman, BA	1
Ackerman, MS; Korc, M; Roeske, WR	1
Hollingsworth, PJ; Smith, CB	1
Ackerman, MS; Heck, RJ; Korc, M; Roeske, WR	1
Palm, D; Pitschner, HF; Schlepper, M; Schulte, B; Wellstein, A	1
Shimizu, H; Watanabe, H	1
Bali, JP; Magous, R; Moummi, C; Strosberg, D	1
Ek, B; Nahorski, S	1
Amrhein, CL; Cioffi, CL; el-Fakahany, EE; McKinney, M; Richelson, E; Stenstrom, S; Surichamorn, W	1
Costa, LG	1
Hsu, CT; Hyman, PE; Jing, J; Snape, WJ; Tomomasa, T	1
Anderson, W; Dickinson, KE; Hirschowitz, BI; Matsumoto, H; Pruitt, RE; Uemura, N	1
Wilkerson, RD	1
Chuang, DM; Xu, J	1
Gillin, JC; Janowsky, D; Risch, SC; Ziegler, M	1
Miranda, HI; Silva, WI; Wolstenholme, WW	1
Auriga, C; Birdsall, NJ; Boer, R; Schudt, C	1
Abdel-Latif, AA; Honkanen, RE	1
Dwyer, TM; Farley, JM; Yang, CM	1
Fisher, SK	1
Davis, LH; Kauffman, FC; Viana, GB	1
Ahmad, A; Chiang, PK; Gordon, RK	1
Bali, JP; Baudiere, B; Giraldo, E; Ladinsky, H; Monferini, E	1
Ban, T; Shingai, R; Usami, K	1
Christophe, J; Gillard, M; Waelbroeck, M	1
Baker, SP; Posner, P	1
Barlow, RB; Dawson, S	1
el-Fakahany, EE; Lee, JH	1
Giraldo, E; Hammer, R; Monferini, E	1
Ehlert, FJ; Jenden, DJ	1
Alatienne, M; Duchene-Marullaz, P; Gueorguiev, G; Kantelip, JP	1
Ellis, J; Lenox, RH	1
El-Fakahany, EE; Feigenbaum, P	1
Harden, TK; Petch, LA; Traynelis, SF; Waldo, GL	1
Eckelman, WC; Francis, B; Gibson, RE; Grissom, MP; Reba, RC	1
Kuhar, MJ; Lepor, H	2
Christophe, J; De Neef, P; Robberecht, P; Waelbroeck, M	1
Moreno-Yanes, JA; Salazar, J	1
Daniotti, S; Del Soldato, P	1
Baissat, J; Chassaing, C; Duchêne-Marullaz, P; Dureng, G	1
Albinus, M; Winne, D	1
Kuhar, MJ; Wamsley, JK; Zarbin, MA	1
Blozovski, D; Hennocq, N	1
Klein, WL; Siman, RG	1
Hammer, R	1
Hirshkowitz, M; Karacan, I; Thornby, JI	1
Hughes, RA	1
Hjälmås, K; Rubenson, A; Sillén, U	1
Glick, SD; Guido, RA	1
Leppik, R; van Giersbergen, PL	1
Christopoulos, A; Mitchelson, F	1
Chowdhury, P; Doi, R; Inoue, K; Kaji, H; Rayford, PL	1
Bellido, I; Gomez, A; Sanchez de la Cuesta, F	1
Proska, J; Tucek, S	1
Butler, T; Dobbie, JW; Duffield, R; Hjelle, JT; Ho, AK; Miller-Hjelle, MA; Reith, M; Steidley, KR	1
Bacáková, L; el-Fakahany, EE; Jakubík, J; Tucek, S	1
Jones, SB; King, LB	1
Brann, MR; Burstein, ES; Spalding, TA	1
Birdsall, NJ; Clementi, F; Court, JA; Griffiths, M; Johnson, M; Kerwin, JM; Morris, CM; Oakley, AE; Perry, EK; Spurden, D	1
Kim, CY; Sohn, UD	1
Christopoulos, A; Lanzafame, A; Mitchelson, F	2
Allal, C; Brefel-Courbon, C; Gharib, C; Lazartigues, E; Montastruc, JL; Rascol, O; Tran, MA	1
Bartoszko-Malik, A; Raufman, JP; Zimniak, P	1
Harbon, S; Lajat, S; Tanfin, Z	1
Maullu, C; Olianas, MC; Onali, P	1
Fu, HM; Fu, ML; Hjalmarson, A; Matsui, S; Wallukat, G	1
Fang, JC; Liu, J; Mittal, RK; Sarosiek, I; Yamamoto, Y	1
Christopoulos, A; El-Fakahany, EE; Parsons, AM	1
Curtis, CA; Hulme, EC; Ward, SD	1
Chang, DJ; Cho, NJ; Hwang, JM; Kaang, BK; Kim, US; Lee, YS; Park, YS	1
De Bruin, VM; De Sousa, FC; Marinho, MM; Viana, GS	1
Janowsky, DS	1
El-Fakahany, EE; Jakubík, J; Tucek, S	1
Corner, B	1
HERXHEIMER, A	1
Azpiazu, I; Gautam, N	1
Barak, D; Pittel, Z; Segall, Y	1
De Lorme, KC; El-Fakahany, EE; Grant, MK; Sikorski, KL	1
Hatanaka, T; Miyata, K; Noguchi, Y; Ohtake, A; Okutsu, H; Saitoh, C; Sasamata, M; Sato, S; Suzuki, M; Ukai, M; Yuyama, H	1
Appadu, BL; Cembala, TM; Forde, SC; Lambert, DG	1
Avlani, VA; Christopoulos, A; McLoughlin, DJ; Sexton, PM	1
Huang, TJ; Ko, WC; Lin, LH; Lin, YL; Wang, SH; Wu, SN	1
El-Fakahany, EE; Grant, MK; Noetzel, MJ	1
Christopoulos, A; Sexton, PM; Stewart, GD	1
Anisuzzaman, AS; Cheng, JT; Lee, KS; Muramatsu, I; Nishimune, A; Suzuki, F; Wang, MH; Yoshiki, H	1
Anisuzzaman, AS; Muramatsu, I; Nishimune, A; Uwada, J; Yoshiki, H	1
Anisuzzaman, AS; Hayashi, H; Ikeuchi, H; Khan, MR; Ma, Y; Maemoto, A; Muramatsu, I; Semba, S; Suzuki, Y; Takano, T; Taniguchi, T; Uchino, M; Ushikubi, F; Uwada, J	1
Catterall, WA; Cheah, CS; Kalume, F; Oakley, JC; Scheuer, T; Westenbroek, RE; Yu, FH	1
Anisuzzaman, ASM; Morishima, S; Muramatsu, I; Uwada, J; Yoshiki, H	1

Trials

1 trial(s) available for n-methylscopolamine and atropine

Article	Year
Cholinergic blockade inhibits gastro-oesophageal reflux and transient lower oesophageal sphincter relaxation through a central mechanism. Gut, 1999, Volume: 44, Issue:5 Topics: Adult; Atropine; Cholinergic Antagonists; Esophagogastric Junction; Esophagus; Female; Gastroesophageal Reflux; Humans; Hydrogen-Ion Concentration; Male; Manometry; Middle Aged; Muscle Relaxation; N-Methylscopolamine; Parasympatholytics; Peristalsis; Pressure	1999

Article

Year

Cholinergic blockade inhibits gastro-oesophageal reflux and transient lower oesophageal sphincter relaxation through a central mechanism.

Gut, 1999, Volume: 44, Issue:5

Topics: Adult; Atropine; Cholinergic Antagonists; Esophagogastric Junction; Esophagus; Female; Gastroesophageal Reflux; Humans; Hydrogen-Ion Concentration; Male; Manometry; Middle Aged; Muscle Relaxation; N-Methylscopolamine; Parasympatholytics; Peristalsis; Pressure

1999

Other Studies

115 other study(ies) available for n-methylscopolamine and atropine

Article	Year
On the unique binding and activating properties of xanomeline at the M1 muscarinic acetylcholine receptor. Molecular pharmacology, 1998, Volume: 53, Issue:6 Topics: Animals; Atropine; Carbachol; CHO Cells; Cricetinae; Dose-Response Relationship, Drug; Humans; Muscarinic Agonists; N-Methylscopolamine; Nitric Oxide Synthase; Phosphatidylinositols; Pyridines; Receptor, Muscarinic M1; Receptors, Muscarinic; Thiadiazoles; Time Factors	1998
Synthesis and pharmacological characterization of O-alkynyloximes of tropinone and N-methylpiperidinone as muscarinic agonists. Journal of medicinal chemistry, 1998, Aug-13, Volume: 41, Issue:17 Topics: Animals; Aorta; Binding, Competitive; Drug Design; Escape Reaction; In Vitro Techniques; Male; Maze Learning; Mice; Models, Molecular; Molecular Structure; Muscarinic Agonists; Muscle Contraction; Muscle, Smooth, Vascular; N-Methylscopolamine; Nuclear Magnetic Resonance, Biomolecular; Piperidines; Pirenzepine; Rabbits; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Structure-Activity Relationship; Tropanes	1998
Pharmacological properties of (2R)-N-[1-(6-aminopyridin-2-ylmethyl)piperidin-4-yl]-2-[(1R)-3,3-difluorocyclopentyl]-2-hydroxy-2-phenylacetamide: a novel mucarinic antagonist with M(2)-sparing antagonistic activity. The Journal of pharmacology and experimental therapeutics, 2001, Volume: 297, Issue:2 Topics: Animals; Benzeneacetamides; Brain; Bronchoconstriction; Heart Atria; Heart Rate; Humans; In Vitro Techniques; Male; Mice; Mice, Inbred ICR; Muscarinic Antagonists; Muscle, Smooth; Muscle, Smooth, Vascular; Piperidines; Pirenzepine; Pyridines; Rabbits; Rats; Rats, Sprague-Dawley; Receptor, Muscarinic M2; Receptors, Muscarinic; Trachea; Tremor; Vas Deferens	2001
Receptor binding studies of soft anticholinergic agents. AAPS pharmSci, 2001, Volume: 3, Issue:4 Topics: Animals; Cholinergic Antagonists; Dose-Response Relationship, Drug; Drug Stability; Guinea Pigs; Humans; Ileum; Protein Binding; Quantitative Structure-Activity Relationship; Receptors, Muscarinic	2001
Lithocholylcholine, a bile acid/acetylcholine hybrid, is a muscarinic receptor antagonist. The Journal of pharmacology and experimental therapeutics, 2002, Volume: 303, Issue:1 Topics: Acetylcholine; Acetylcholinesterase; Animals; Aorta, Thoracic; Atropine; Carbachol; CHO Cells; Cricetinae; In Vitro Techniques; Inositol Phosphates; Kinetics; Lithocholic Acid; Male; Muscarinic Antagonists; Muscle, Smooth; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Recombinant Proteins; Taurolithocholic Acid	2002
Identification of various allosteric interaction sites on M1 muscarinic receptor using 125I-Met35-oxidized muscarinic toxin 7. Molecular pharmacology, 2006, Volume: 69, Issue:5 Topics: Allosteric Regulation; Binding Sites; Elapid Venoms; Humans; Iodine Radioisotopes; Kinetics; Ligands; Methionine; Oxidation-Reduction; Protein Folding; Receptor, Muscarinic M1; Spectrometry, Mass, Electrospray Ionization	2006
Quantifying the association and dissociation rates of unlabelled antagonists at the muscarinic M3 receptor. British journal of pharmacology, 2006, Volume: 148, Issue:7 Topics: Algorithms; Animals; Atropine; Binding, Competitive; Cell Membrane; CHO Cells; Cricetinae; Indicators and Reagents; Kinetics; Ligands; Muscarinic Antagonists; N-Methylscopolamine; Radioligand Assay; Receptor, Muscarinic M3; Scopolamine Derivatives; Tiotropium Bromide	2006
Distinct structural changes in a G protein-coupled receptor caused by different classes of agonist ligands. The Journal of biological chemistry, 2007, Sep-07, Volume: 282, Issue:36 Topics: Amino Acid Substitution; Animals; Chlorocebus aethiops; COS Cells; Cysteine; Ligands; Models, Molecular; Mutation, Missense; Protein Structure, Secondary; Protein Structure, Tertiary; Rats; Receptor, Muscarinic M3	2007
Fluorescent derivatives of AC-42 to probe bitopic orthosteric/allosteric binding mechanisms on muscarinic M1 receptors. Journal of medicinal chemistry, 2012, Mar-08, Volume: 55, Issue:5 Topics: Allosteric Regulation; Calcium; Fluorescence Resonance Energy Transfer; Fluorescent Dyes; Green Fluorescent Proteins; HEK293 Cells; Humans; Models, Molecular; Molecular Probes; Piperidines; Radioligand Assay; Receptor, Muscarinic M1; Recombinant Fusion Proteins; Rhodamines; Solubility; Structure-Activity Relationship	2012
Radiolabeled Dibenzodiazepinone-Type Antagonists Give Evidence of Dualsteric Binding at the M Journal of medicinal chemistry, 2017, 04-27, Volume: 60, Issue:8 Topics: Benzodiazepinones; Binding Sites; Molecular Dynamics Simulation; Muscarinic Antagonists; Radioisotopes; Receptor, Muscarinic M2	2017
Red-Emitting Dibenzodiazepinone Derivatives as Fluorescent Dualsteric Probes for the Muscarinic Acetylcholine M Journal of medicinal chemistry, 2020, 04-23, Volume: 63, Issue:8 Topics: Animals; CHO Cells; Cholinergic Agents; Cricetulus; Fluorescent Dyes; Muscarinic Antagonists; Phthalimides; Protein Structure, Secondary; Quaternary Ammonium Compounds; Receptor, Muscarinic M2	2020
Central cardiovascular effects of physostigmine in anesthetized cats. Neuropharmacology, 1992, Volume: 31, Issue:9 Topics: Anesthesia; Animals; Atropine; Blood Pressure; Cats; Dose-Response Relationship, Drug; Female; Heart Rate; Hemodynamics; Kidney; Male; N-Methylscopolamine; Physostigmine; Receptors, Muscarinic; Scopolamine Derivatives; Sympathetic Nervous System; Vagotomy	1992
Apparent noncompetitive antagonism of muscarinic receptor mediated Ca2+ mobilization by some muscarinic antagonists. Biochemical and biophysical research communications, 1992, Dec-15, Volume: 189, Issue:2 Topics: Atropine; Calcium; Fura-2; Humans; Kinetics; Muscarinic Antagonists; N-Methylscopolamine; Neuroblastoma; Parasympatholytics; Piperidines; Pirenzepine; Receptors, Muscarinic; Scopolamine Derivatives; Spectrometry, Fluorescence; Tumor Cells, Cultured	1992
The muscarinic receptor gene expressed in rabbit parietal cells is the m3 subtype. Gastroenterology, 1992, Volume: 103, Issue:3 Topics: Animals; Atropine; Base Sequence; Blotting, Southern; Molecular Sequence Data; N-Methylscopolamine; Parietal Cells, Gastric; Piperidines; Pirenzepine; Polymerase Chain Reaction; Rabbits; Receptors, Muscarinic; RNA, Messenger; Scopolamine Derivatives	1992
Characterization of muscarinic cholinergic receptors in intact myocardial cells in vitro. Biochemical pharmacology, 1992, Jun-09, Volume: 43, Issue:11 Topics: Animals; Atropine; Cells, Cultured; Down-Regulation; Electric Stimulation; Gallopamil; Half-Life; Kinetics; Myocardial Contraction; Myocardium; N-Methylscopolamine; Radioligand Assay; Rats; Receptors, Muscarinic; Scopolamine Derivatives; Thyroid Hormones	1992
Muscarinic receptor subtypes in human and rat colon smooth muscle. Biochemical pharmacology, 1992, Jun-09, Volume: 43, Issue:11 Topics: Animals; Atropine; Binding, Competitive; Colon; Humans; Infant, Newborn; Male; Muscle, Smooth; N-Methylscopolamine; Pirenzepine; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Scopolamine Derivatives	1992
Anti-muscarinic drug effects in a swim-to-platform test: dose-response relations. Behavioural brain research, 1991, Aug-29, Volume: 44, Issue:2 Topics: Animals; Atropine; Behavior, Animal; Dose-Response Relationship, Drug; Injections, Intraperitoneal; Injections, Subcutaneous; Male; N-Methylscopolamine; Parasympatholytics; Rats; Scopolamine; Scopolamine Derivatives; Swimming	1991
Interaction of the neuromuscular blocking drug atracurium with muscarinic acetylcholine receptors. Physiological research, 1991, Volume: 40, Issue:3 Topics: Animals; Atracurium; Atropine; Cerebral Cortex; Dose-Response Relationship, Drug; Drug Interactions; Female; Heart Atria; Male; Muscarine; Muscle, Smooth; N-Methylscopolamine; Parasympatholytics; Parasympathomimetics; Quinuclidinyl Benzilate; Rats; Rats, Inbred Strains; Receptors, Cholinergic; Scopolamine Derivatives; Tritium	1991
Characterization of muscarinic receptors in dog tracheal smooth muscle cells. Journal of autonomic pharmacology, 1991, Volume: 11, Issue:1 Topics: Animals; Atropine; Carbachol; Diamines; Dogs; In Vitro Techniques; Kinetics; Muscle, Smooth; N-Methylscopolamine; Parasympatholytics; Piperidines; Pirenzepine; Receptors, Muscarinic; Scopolamine Derivatives; Trachea	1991
Regulation of muscarinic agonist-induced activation of phosphoinositidase C in electrically permeabilized SH-SY5Y human neuroblastoma cells by guanine nucleotides. Journal of neurochemistry, 1990, Volume: 54, Issue:2 Topics: Atropine; Calcium; Cell Membrane Permeability; Electric Stimulation; Guanine Nucleotides; Humans; N-Methylscopolamine; Neuroblastoma; Parasympatholytics; Parasympathomimetics; Phosphoric Diester Hydrolases; Scopolamine Derivatives; Tumor Cells, Cultured	1990
Muscarinic antagonist binding to intact rat thymocytes. Acta chemica Scandinavica (Copenhagen, Denmark : 1989), 1990, Volume: 44, Issue:2 Topics: Animals; Atropine; Benzilates; Kinetics; Male; Muscarine; N-Methylscopolamine; Piperidines; Quinuclidinyl Benzilate; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Scopolamine Derivatives; Thymus Gland	1990
Carbachol-induced potentiation and inhibition of acid secretion by guinea pig gastric gland. European journal of pharmacology, 1990, Mar-13, Volume: 178, Issue:1 Topics: Aminopyrine; Animals; Atropine; Binding, Competitive; Carbachol; Dose-Response Relationship, Drug; Gastric Acid; Gastric Mucosa; Guinea Pigs; Histamine; In Vitro Techniques; Male; N-Methylscopolamine; Parasympathomimetics; Pirenzepine; Receptors, Muscarinic; Scopolamine Derivatives	1990
[3H]N-methylscopolamine binding studies reveal M2 and M3 muscarinic receptor subtypes on cerebellar granule cells in primary culture. Journal of neurochemistry, 1990, Volume: 55, Issue:1 Topics: Animals; Atropine; Binding, Competitive; Cell Survival; Cells, Cultured; Cerebellum; Diamines; Granulocytes; N-Methylscopolamine; Parasympatholytics; Piperidines; Pirenzepine; Receptors, Muscarinic; Scopolamine Derivatives; Tritium	1990
The allosteric binding profile of himbacine: a comparison with other cardioselective muscarinic antagonists. European journal of pharmacology, 1990, Apr-10, Volume: 179, Issue:1-2 Topics: Alkaloids; Allosteric Regulation; Animals; Atropine; Binding, Competitive; Diamines; Dose-Response Relationship, Drug; Furans; Gallamine Triethiodide; Male; Myocardium; N-Methylscopolamine; Naphthalenes; Piperidines; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Scopolamine Derivatives	1990
Aprophit: an irreversible antagonist for muscarinic receptors. Biochemical pharmacology, 1990, Sep-15, Volume: 40, Issue:6 Topics: Adrenal Glands; Animals; Atropine; Binding, Competitive; Brain; Catecholamines; Guinea Pigs; Male; N-Methylscopolamine; Parasympatholytics; Phenylpropionates; Pirenzepine; Rats; Receptors, Muscarinic; Scopolamine Derivatives; Thiocyanates	1990
A cholinergic antagonist identifies a subclass of muscarinic receptors in isolated rat pancreatic acini. The Journal of pharmacology and experimental therapeutics, 1987, Volume: 240, Issue:1 Topics: Amylases; Animals; Atropine; Carbachol; Cerebral Cortex; Dose-Response Relationship, Drug; Kinetics; Male; Myocardium; N-Methylscopolamine; Pancreas; Pirenzepine; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Scopolamine Derivatives	1987
Effects of muscarinic receptor agonists and antagonists on alpha 2-adrenoceptors in rat brain. European journal of pharmacology, 1989, Sep-13, Volume: 168, Issue:2 Topics: Animals; Atropine; Atropine Derivatives; Brain; Clonidine; Male; N-Methylscopolamine; Neurons; Oxotremorine; Parasympatholytics; Pilocarpine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Muscarinic; Scopolamine; Scopolamine Derivatives; Time Factors	1989
Identification and characterization of muscarinic receptors in cultured human pancreatic carcinoma cells. Pancreas, 1989, Volume: 4, Issue:3 Topics: Atropine; Carbachol; Cell Line; Humans; Inositol Phosphates; Kinetics; N-Methylscopolamine; Pancreatic Neoplasms; Parasympatholytics; Pirenzepine; Receptors, Muscarinic; Scopolamine Derivatives; Tumor Cells, Cultured	1989
AF-DX 116 discriminates heart from gland M2-cholinoceptors in man. Life sciences, 1989, Volume: 45, Issue:6 Topics: Adult; Animals; Atropine; Blood Pressure; Cattle; Cell Membrane; Cerebral Cortex; Heart Rate; Humans; Kinetics; Male; Myocardium; N-Methylscopolamine; Organ Specificity; Pirenzepine; Propranolol; Receptors, Cholinergic; Reference Values; Saliva; Salivary Glands; Scopolamine Derivatives; Swine	1989
Effect of anticholinergic drugs on striatal acetylcholine release and motor activity in freely moving rats studied by brain microdialysis. Japanese journal of pharmacology, 1989, Volume: 51, Issue:1 Topics: Acetylcholine; Animals; Atropine; Brain Chemistry; Corpus Striatum; Dialysis; Male; Motor Activity; N-Methylscopolamine; Parasympatholytics; Rats; Rats, Inbred Strains; Scopolamine; Scopolamine Derivatives; Tissue Distribution	1989
Muscarinic receptors in isolated smooth muscle cells from gastric antrum. Biochemical pharmacology, 1988, Apr-01, Volume: 37, Issue:7 Topics: Acetylcholine; Animals; Antibodies, Monoclonal; Atropine; Cyclic AMP; Dose-Response Relationship, Drug; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; N-Methylscopolamine; Pyloric Antrum; Rabbits; Receptors, Muscarinic; Scopolamine Derivatives	1988
Muscarinic receptor coupling to inositol phospholipid metabolism in guinea-pig cerebral cortex, parotid gland and ileal smooth muscle. Biochemical pharmacology, 1988, Dec-01, Volume: 37, Issue:23 Topics: Animals; Atropine; Carbachol; Cerebral Cortex; Guanosine Triphosphate; Guinea Pigs; Ileum; Muscle, Smooth; N-Methylscopolamine; Oxotremorine; Parotid Gland; Phosphatidylinositols; Pirenzepine; Receptors, Muscarinic; Scopolamine Derivatives	1988
Pseudo-noncompetitive antagonism of muscarinic receptor-mediated cyclic GMP formation and phosphoinositide hydrolysis by pirenzepine. The Journal of pharmacology and experimental therapeutics, 1988, Volume: 247, Issue:3 Topics: Animals; Atropine; Carbachol; Cyclic GMP; Hydrolysis; Mice; N-Methylscopolamine; Phosphatidylinositols; Pirenzepine; Receptors, Muscarinic; Scopolamine Derivatives	1988
Specific binding of [3H]methylscopolamine to glass fibre filters. The Journal of pharmacy and pharmacology, 1987, Volume: 39, Issue:3 Topics: Animals; Aplysia; Atropine; Atropine Derivatives; Chemical Phenomena; Chemistry, Physical; Filtration; gamma-Aminobutyric Acid; Glass; N-Methylscopolamine; Norepinephrine; Receptors, Muscarinic; Scopolamine; Scopolamine Derivatives	1987
Development of the muscarinic receptor in rabbit gastric smooth muscle. The American journal of physiology, 1988, Volume: 254, Issue:5 Pt 1 Topics: Animals; Animals, Newborn; Atropine; Bethanechol; Bethanechol Compounds; Dose-Response Relationship, Drug; Kinetics; Muscle Contraction; Muscle Development; Muscle, Smooth; N-Methylscopolamine; Phenethylamines; Piperidines; Rabbits; Receptors, Muscarinic; Scopolamine Derivatives; Stomach	1988
Muscarinic cholinergic receptor subtype on frog esophageal peptic cells: binding and secretion studies. The Journal of pharmacology and experimental therapeutics, 1988, Volume: 246, Issue:3 Topics: Acetylcholine; Animals; Atropine; Bethanechol; Bethanechol Compounds; Carbachol; Esophagus; Imipramine; Kinetics; N-Methylscopolamine; Oxotremorine; Pepsinogens; Pirenzepine; Propranolol; Radioligand Assay; Rana catesbeiana; Receptors, Muscarinic; Scopolamine Derivatives	1988
Cardiovascular effects of cocaine: enhancement by yohimbine and atropine. The Journal of pharmacology and experimental therapeutics, 1989, Volume: 248, Issue:1 Topics: Animals; Atropine; Blood Pressure; Cardiovascular System; Cocaine; Coronary Circulation; Dogs; Heart Rate; Myocardial Contraction; N-Methylscopolamine; Norepinephrine; Oxygen Consumption; Scopolamine Derivatives; Yohimbine	1989
Muscarinic acetylcholine receptor-mediated phosphoinositide turnover in cultured cerebellar granule cells: desensitization by receptor agonists. The Journal of pharmacology and experimental therapeutics, 1987, Volume: 242, Issue:1 Topics: Animals; Atropine; Carbachol; Cells, Cultured; Cerebellum; Kinetics; Male; N-Methylscopolamine; Oxotremorine; Phorbol Esters; Phosphatidylinositols; Pirenzepine; Quinuclidinyl Benzilate; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Scopolamine Derivatives; Virulence Factors, Bordetella	1987
Antagonistic effects of scopolamine and atropine on the physostigmine response in man. Military medicine, 1987, Volume: 152, Issue:11 Topics: Adult; Affect; Atropine; Cardiovascular System; Double-Blind Method; Drug Evaluation; Humans; Male; N-Methylscopolamine; Neurosecretory Systems; Parasympatholytics; Physostigmine; Scopolamine; Scopolamine Derivatives	1987
Pre- and post-synaptic muscarinic receptors of the rat vas deferens: an update. Puerto Rico health sciences journal, 1988, Volume: 7, Issue:2 Topics: Animals; Atropine; Binding, Competitive; Male; Membrane Potentials; Muscle, Smooth; N-Methylscopolamine; Neuromuscular Junction; Pirenzepine; Rats; Rats, Inbred Strains; Receptors, Cholinergic; Receptors, Muscarinic; Scopolamine Derivatives; Synapses; Terminology as Topic; Vas Deferens	1988
Does the prolonged occupancy of M1 receptors by telenzepine protect them against the action of vagally released acetylcholine? Pharmacology, 1988, Volume: 37 Suppl 1 Topics: Acetylcholine; Animals; Atropine; Binding, Competitive; Brain; Cattle; In Vitro Techniques; Kinetics; N-Methylscopolamine; Pirenzepine; Rats; Receptors, Muscarinic; Scopolamine Derivatives; Vagus Nerve	1988
Characterization of cholinergic muscarinic receptors in the rabbit iris. Biochemical pharmacology, 1988, Jul-01, Volume: 37, Issue:13 Topics: Animals; Atropine; Carbachol; Cerebral Cortex; Ileum; Iris; Kinetics; Methacholine Chloride; Methacholine Compounds; Microsomes; N-Methylscopolamine; Oxotremorine; Pirenzepine; Quinuclidinyl Benzilate; Rabbits; Receptors, Muscarinic; Scopolamine Derivatives	1988
Muscarinic stimulation of submucosal glands in swine trachea. Journal of applied physiology (Bethesda, Md. : 1985), 1988, Volume: 64, Issue:1 Topics: Animals; Atropine; Binding, Competitive; Carbachol; Exocrine Glands; Isoflurophate; Male; Mucus; N-Methylscopolamine; Pirenzepine; Quinuclidinyl Benzilate; Receptors, Muscarinic; Scopolamine Derivatives; Swine; Trachea	1988
Recognition of muscarinic cholinergic receptors in human SK-N-SH neuroblastoma cells by quaternary and tertiary ligands is dependent upon temperature, cell integrity, and the presence of agonists. Molecular pharmacology, 1988, Volume: 33, Issue:4 Topics: Atropine; Binding, Competitive; Carbachol; Humans; Kinetics; Ligands; N-Methylscopolamine; Neuroblastoma; Quinuclidinyl Benzilate; Receptors, Muscarinic; Scopolamine; Scopolamine Derivatives; Temperature; Tumor Cells, Cultured	1988
Effects of organophosphates and nerve growth factor on muscarinic receptor binding number in rat pheochromocytoma PC12 cells. Toxicology and applied pharmacology, 1988, Volume: 93, Issue:2 Topics: Animals; Atropine; Cholinesterases; Dose-Response Relationship, Drug; N-Methylscopolamine; Nerve Growth Factors; Organophosphorus Compounds; Pheochromocytoma; Phosphorylation; Physostigmine; Rats; Receptors, Muscarinic; Scopolamine Derivatives; Soman; Tumor Cells, Cultured	1988
Influence of ligand choice on the apparent binding profile of gallamine to cardiac muscarinic receptors. Identification of three main types of gallamine-muscarinic receptor interactions. The Journal of pharmacology and experimental therapeutics, 1988, Volume: 246, Issue:3 Topics: Algorithms; Alkylation; Animals; Atropine; Binding Sites; Gallamine Triethiodide; Male; Myocardium; N-Methylscopolamine; Quinuclidinyl Benzilate; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Scopolamine Derivatives	1988
A microtechnique for quantification of detergent-solubilized muscarinic and nicotinic acetylcholine receptors using a semi-automated cell harvestor. FEBS letters, 1987, Apr-20, Volume: 214, Issue:2 Topics: Animals; Atropine; Bungarotoxins; Digitonin; In Vitro Techniques; Microchemistry; N-Methylscopolamine; Neuroblastoma; Polyethylene Glycols; Quinuclidinyl Benzilate; Receptors, Muscarinic; Receptors, Nicotinic; Scopolamine Derivatives; Solubility	1987
Characterization of the muscarinic receptor subtype in isolated gastric fundic cells of the rabbit. Biochemical pharmacology, 1987, Sep-15, Volume: 36, Issue:18 Topics: Aminopyrine; Animals; Atropine; Carbachol; Gastric Fundus; Kinetics; Male; N-Methylscopolamine; Piperidines; Pirenzepine; Rabbits; Receptors, Muscarinic; Scopolamine Derivatives	1987
Muscarinic cholinergic receptor binding and electrophysiological response to acetylcholine in cultured rat caudate putamen nucleus neurons. Brain research, 1987, Sep-08, Volume: 420, Issue:1 Topics: Acetylcholine; Action Potentials; Animals; Atropine; Caudate Nucleus; Cells, Cultured; N-Methylscopolamine; Putamen; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Scopolamine Derivatives	1987
In vitro effects of gallamine on dissociation kinetics of (3H)N-methylscopolamine and (3H)pirenzepine from rat brain muscarinic receptors. Journal of receptor research, 1986, Volume: 6, Issue:1 Topics: Animals; Atropine; Benzodiazepinones; Binding, Competitive; Cerebral Cortex; Corpus Striatum; Gallamine Triethiodide; Hippocampus; Kinetics; Male; Myocardium; N-Methylscopolamine; Pirenzepine; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Scopolamine Derivatives; Substrate Specificity	1986
Irreversible binding of acetylethylcholine mustard to cardiac cholinergic muscarinic receptors. Molecular pharmacology, 1986, Volume: 30, Issue:5 Topics: Acetylcholine; Animals; Atropine; Carbachol; Cell Membrane; Guanylyl Imidodiphosphate; Heart Rate; Male; Myocardium; N-Methylscopolamine; Oxotremorine; Quinuclidinyl Benzilate; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Scopolamine Derivatives	1986
The selectivity of the (-)-and (+)-forms of hyoscine methiodide and of hyoscyamine camphorsulphonate for muscarinic (M2) receptors. British journal of pharmacology, 1986, Volume: 89, Issue:2 Topics: Animals; Atropine; Guinea Pigs; Heart; Ileum; In Vitro Techniques; Muscle, Smooth; Myocardial Contraction; N-Methylscopolamine; Receptors, Muscarinic; Scopolamine; Scopolamine Derivatives; Stereoisomerism	1986
Agonist-induced muscarinic acetylcholine receptor down-regulation in intact rat brain cells. European journal of pharmacology, 1986, Dec-02, Volume: 132, Issue:1 Topics: Animals; Atropine; Brain; Carbachol; Female; In Vitro Techniques; Male; N-Methylscopolamine; Parasympathomimetics; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Scopolamine Derivatives	1986
Selective labelling of M1-receptors in autonomic ganglia with 3H-pirenzepine. Arzneimittel-Forschung, 1985, Volume: 35, Issue:1A Topics: Animals; Atropine; Benzodiazepinones; Binding, Competitive; Cattle; Ganglia, Autonomic; Ganglia, Sympathetic; In Vitro Techniques; N-Methylscopolamine; Pirenzepine; Quinuclidinyl Benzilate; Radioligand Assay; Receptors, Muscarinic; Scopolamine Derivatives; Synaptosomes	1985
The binding of a 2-chloroethylamine derivative of oxotremorine (BM 123) to muscarinic receptors in the rat cerebral cortex. Molecular pharmacology, 1985, Volume: 28, Issue:2 Topics: Alkylation; Animals; Atropine; Benzodiazepinones; Binding Sites; Binding, Competitive; Cerebral Cortex; Gallamine Triethiodide; Kinetics; N-Methylscopolamine; Oxotremorine; Pirenzepine; Pyrrolidinones; Quinuclidinyl Benzilate; Rats; Receptors, Muscarinic; Scopolamine Derivatives; Structure-Activity Relationship; Thiosulfates	1985
Chronotropic and dromotropic effects of atropine and hyoscine methobromide in unanaesthetized dogs. British journal of anaesthesia, 1985, Volume: 57, Issue:2 Topics: Animals; Atropine; Autonomic Nervous System; Cardiac Pacing, Artificial; Dogs; Electrocardiography; Heart Conduction System; Heart Rate; N-Methylscopolamine; Parasympatholytics; Propranolol; Scopolamine Derivatives; Stimulation, Chemical; Time Factors	1985
Quaternary forms of classical muscarinic antagonists distinguish subpopulations of muscarinic receptors: correlation with gallamine-defined subpopulations. Biochemical and biophysical research communications, 1985, Feb-15, Volume: 126, Issue:3 Topics: Allosteric Site; Animals; Atropine; Atropine Derivatives; Binding, Competitive; Brain; Gallamine Triethiodide; In Vitro Techniques; Male; N-Methylscopolamine; Parasympatholytics; Quinuclidinyl Benzilate; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Scopolamine; Scopolamine Derivatives	1985
Regulation of muscarinic cholinergic receptor density in neuroblastoma cells by brief exposure to agonist: possible involvement in desensitization of receptor function. The Journal of pharmacology and experimental therapeutics, 1985, Volume: 233, Issue:1 Topics: Animals; Atropine; Carbachol; Cell Differentiation; Cell Line; Dose-Response Relationship, Drug; Mice; N-Methylscopolamine; Neuroblastoma; Parasympathomimetics; Receptors, Muscarinic; Scopolamine Derivatives; Temperature	1985
Agonist-induced alteration in the membrane form of muscarinic cholinergic receptors. The Journal of biological chemistry, 1985, Oct-25, Volume: 260, Issue:24 Topics: Astrocytoma; Atropine; Carbachol; Cell Fractionation; Cell Line; Cell Membrane; Centrifugation, Density Gradient; Guanosine Triphosphate; Humans; Kinetics; N-Methylscopolamine; Quinuclidinyl Benzilate; Receptors, Muscarinic; Scopolamine Derivatives	1985
The use of tritium labeled compounds to develop gamma-emitting receptor-binding radiotracers. International journal of nuclear medicine and biology, 1982, Volume: 9, Issue:3 Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Atropine; Dihydroalprenolol; Dioxanes; Dogs; Guinea Pigs; Heart; Humans; Male; N-Methylscopolamine; Parasympatholytics; Pindolol; Prazosin; Propanolamines; Quinuclidinyl Benzilate; Rabbits; Radionuclide Imaging; Rats; Scopolamine Derivatives; Tritium	1982
Characterization and localization of the muscarinic cholinergic receptor in human prostatic tissue. The Journal of urology, 1984, Volume: 132, Issue:2 Topics: Animals; Atropine; Autoradiography; Binding, Competitive; Dogs; Humans; In Vitro Techniques; Male; N-Methylscopolamine; Prostate; Prostatic Hyperplasia; Rabbits; Radioligand Assay; Receptors, Muscarinic; Scopolamine Derivatives; Swine	1984
Inhibitory effects of quinidine on rat heart muscarinic receptors. Life sciences, 1984, Sep-03, Volume: 35, Issue:10 Topics: Animals; Atropine; Binding, Competitive; Heart; Kinetics; Mathematics; Myocardium; N-Methylscopolamine; Oxotremorine; Quinidine; Rats; Receptors, Muscarinic; Scopolamine Derivatives	1984
[Biochemical studies on muscarinic cholinergic receptors of the rat brain: specific labeling of this protein using the photoaffinity method]. Acta cientifica venezolana, 1984, Volume: 35, Issue:1 Topics: Affinity Labels; Animals; Atropine; Binding Sites; Brain Chemistry; Cell Membrane; Male; N-Methylscopolamine; Parasympatholytics; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Scopolamine Derivatives	1984
Comparative studies of the effects of some antimuscarinic agents on gastric damage and pupillary reflex in the rat. British journal of pharmacology, 1984, Volume: 82, Issue:2 Topics: Animals; Atropine; Benzodiazepinones; Female; N-Methylscopolamine; Oxotremorine; Parasympatholytics; Pirenzepine; Propantheline; Rats; Rats, Inbred Strains; Reflex, Pupillary; Scopolamine Derivatives; Stomach Diseases	1984
Pharmacological evidence for cardiac muscarinic receptor subtypes. Life sciences, 1984, Oct-22, Volume: 35, Issue:17 Topics: Acetylcholine; Animals; Arecoline; Atropine; Benzodiazepinones; Binding Sites; Butylscopolammonium Bromide; Carbachol; Female; Guinea Pigs; Heart Rate; Male; Myocardial Contraction; Myocardium; N-Methylscopolamine; Pirenzepine; Quaternary Ammonium Compounds; Receptors, Muscarinic; Scopolamine Derivatives	1984
Subclasses of muscarinic receptors in isolated gastric mucosal cells: receptor characterization and parietal cell function. European journal of pharmacology, 1983, Oct-28, Volume: 94, Issue:3-4 Topics: Animals; Atropine; Benzodiazepinones; Binding, Competitive; Carbachol; Dogs; Gastric Mucosa; Guanine Nucleotides; Guinea Pigs; In Vitro Techniques; Male; Models, Biological; N-Methylscopolamine; Pilocarpine; Pirenzepine; Receptors, Muscarinic; Scopolamine Derivatives	1983
Distribution of muscarinic cholinergic high and low affinity agonist binding sites: a light microscopic autoradiographic study. Brain research bulletin, 1984, Volume: 12, Issue:3 Topics: Animals; Atropine; Autoradiography; Brain; Brain Stem; Carbachol; Kinetics; Male; N-Methylscopolamine; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Scopolamine Derivatives; Spinal Cord	1984
Characterization of muscarinic cholinergic receptor binding in the vas deferens, bladder, prostate and penis of the rabbit. The Journal of urology, 1984, Volume: 132, Issue:2 Topics: Animals; Atropine; Binding, Competitive; Diazoxide; Haloperidol; In Vitro Techniques; Male; N-Methylscopolamine; Oxotremorine; Parasympathomimetics; Penis; Phentolamine; Propranolol; Prostate; Rabbits; Radioligand Assay; Receptors, Muscarinic; Scopolamine Derivatives; Urinary Bladder; Vas Deferens	1984
Effects of antimuscarinic cholinergic drugs injected systemically or into the hippocampo-entorhinal area upon passive avoidance learning in young rats. Psychopharmacology, 1982, Volume: 76, Issue:4 Topics: Age Factors; Animals; Atropine; Atropine Derivatives; Avoidance Learning; Extinction, Psychological; Female; Hippocampus; Limbic System; Male; N-Methylscopolamine; Rats; Receptors, Muscarinic; Retention, Psychology; Scopolamine; Scopolamine Derivatives	1982
Differential regulation of muscarinic and nicotinic receptors by cholinergic stimulation in cultured avian retina cells. Brain research, 1983, Feb-28, Volume: 262, Issue:1 Topics: Animals; Atropine; Carbachol; Cells, Cultured; Chick Embryo; N-Methylscopolamine; Neurons; Nicotine; Oxotremorine; Quinuclidinyl Benzilate; Receptors, Cholinergic; Receptors, Muscarinic; Receptors, Nicotinic; Retina; Scopolamine Derivatives; Tubocurarine	1983
Subclasses of muscarinic receptors and pirenzepine. Further experimental evidence. Scandinavian journal of gastroenterology. Supplement, 1982, Volume: 72 Topics: Atropine; Benzodiazepinones; Gastric Juice; Humans; N-Methylscopolamine; Pirenzepine; Receptors, Cholinergic; Receptors, Muscarinic; Scopolamine Derivatives	1982
Sleep spindles: pharmacological effects in humans. Sleep, 1982, Volume: 5, Issue:1 Topics: Atropine; Azepines; Caffeine; Cerebral Cortex; Computers; Dose-Response Relationship, Drug; Double-Blind Method; Electroencephalography; Evoked Potentials; Flurazepam; Haloperidol; Humans; N-Methylscopolamine; Phenobarbital; Scopolamine; Scopolamine Derivatives; Sleep Stages; Thalidomide; Tryptophan	1982
Anticholinergic drugs, blood-brain-barrier and tonic immobility in chickens. Physiology & behavior, 1982, Volume: 29, Issue:1 Topics: Aging; Animals; Atropine; Atropine Derivatives; Blood-Brain Barrier; Chickens; Dose-Response Relationship, Drug; Fear; Motor Activity; N-Methylscopolamine; Parasympatholytics; Scopolamine; Scopolamine Derivatives	1982
Central cholinergic mechanisms in L-DOPA induced hyperactive urinary bladder of the rat. Urological research, 1982, Volume: 10, Issue:5 Topics: Animals; Atropine; Brain; Calcium; Hexamethonium Compounds; Levodopa; Male; N-Methylscopolamine; Oxotremorine; Phentolamine; Rats; Receptors, Adrenergic; Receptors, Cholinergic; Reserpine; Scopolamine Derivatives; Sotalol; Urinary Bladder	1982
Scopolamine self-administration: cholinergic involvement in reward mechanisms. Life sciences, 1982, Aug-30, Volume: 31, Issue:9 Topics: Animals; Arecoline; Atropine; Behavior, Animal; Female; Mecamylamine; N-Methylscopolamine; Oxotremorine; Parasympathetic Nervous System; Physostigmine; Pilocarpine; Rats; Rats, Inbred Strains; Reinforcement, Psychology; Reward; Scopolamine; Scopolamine Derivatives; Self Administration	1982
Modulation of agonist binding by guanine nucleotides in CHO cells expressing muscarinic m1-m5 receptors. Naunyn-Schmiedeberg's archives of pharmacology, 1995, Volume: 352, Issue:2 Topics: Animals; Atropine; Carbachol; CHO Cells; Cricetinae; Guanine Nucleotides; Guanylyl Imidodiphosphate; Humans; Kinetics; Muscarinic Agonists; Muscarinic Antagonists; N-Methylscopolamine; Parasympatholytics; Radioligand Assay; Receptors, Muscarinic; Scopolamine Derivatives	1995
[3H]N-methylscopolamine dissociation from muscarine receptors affected by low concentrations of allosteric modulators. European journal of pharmacology, 1995, Aug-15, Volume: 290, Issue:3 Topics: Allosteric Regulation; Animals; Atropine; Binding, Competitive; Gallamine Triethiodide; Guinea Pigs; In Vitro Techniques; Kinetics; Ligands; Muscarinic Antagonists; N-Methylscopolamine; Nicotinic Antagonists; Parasympatholytics; Receptors, Muscarinic; Scopolamine Derivatives	1995
Structural and functional changes of exocrine pancreas induced by FK506 in rats. Gastroenterology, 1993, Volume: 104, Issue:4 Topics: Amylases; Analysis of Variance; Animals; Atropine; Body Weight; Calcimycin; Calcium; Carbachol; Cholecystokinin; Colforsin; Cytosol; Dose-Response Relationship, Drug; Feeding Behavior; Kinetics; Male; N-Methylscopolamine; Pancreas; Rats; Rats, Sprague-Dawley; Receptors, Cholecystokinin; Reference Values; Scopolamine; Scopolamine Derivatives; Secretin; Sincalide; Tacrolimus; Tetradecanoylphorbol Acetate; Time Factors; Trypsinogen; Vasoactive Intestinal Peptide	1993
Atropine and glycopyrronium show similar binding patterns to M2 (cardiac) and M3 (submandibular gland) muscarinic receptor subtypes in the rat. British journal of anaesthesia, 1995, Volume: 74, Issue:5 Topics: Animals; Atropine; Binding, Competitive; Glycopyrrolate; Heart Ventricles; In Vitro Techniques; Male; N-Methylscopolamine; Parasympatholytics; Pirenzepine; Rats; Rats, Wistar; Receptors, Muscarinic; Scopolamine Derivatives; Submandibular Gland	1995
Mechanisms of steric and cooperative actions of alcuronium on cardiac muscarinic acetylcholine receptors. Molecular pharmacology, 1994, Volume: 45, Issue:4 Topics: Alcuronium; Animals; Atropine; Heart; Kinetics; Male; N-Methylscopolamine; Rats; Rats, Wistar; Receptors, Muscarinic; Scopolamine Derivatives	1994
Multiple drug classes and hyperosmolarity alter binding of muscarinic drugs to mesothelial cells in vitro. Advances in peritoneal dialysis. Conference on Peritoneal Dialysis, 1995, Volume: 11 Topics: Animals; Atropine; Cells, Cultured; Cocaine; Cycloheximide; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Epithelium; Mannitol; Muscarinic Antagonists; N-Methylscopolamine; Osmolar Concentration; Parasympatholytics; Peritoneum; Piperazines; Quinuclidinyl Benzilate; Rabbits; Receptors, Muscarinic; Scopolamine Derivatives; Sodium Chloride	1995
Constitutive activity of the M1-M4 subtypes of muscarinic receptors in transfected CHO cells and of muscarinic receptors in the heart cells revealed by negative antagonists. FEBS letters, 1995, Dec-18, Volume: 377, Issue:2 Topics: Animals; Atropine; Carbachol; Cells, Cultured; CHO Cells; Cricetinae; Cyclic AMP; Humans; Inositol Phosphates; Muscarinic Antagonists; Myocardium; N-Methylscopolamine; Pirenzepine; Quinuclidinyl Benzilate; Rats; Receptors, Muscarinic; Scopolamine Derivatives; Transfection; Tritium	1995
Muscarinic cholinergic receptors in brain and atrial membranes of adult brook trout (Salvelinus fontinalis) measured by radioligand binding techniques. Comparative biochemistry and physiology. Part C, Pharmacology, toxicology & endocrinology, 1995, Volume: 112, Issue:1 Topics: Animals; Atropine; Binding, Competitive; Brain Chemistry; Carbachol; Heart Atria; Kinetics; Muscarinic Agonists; Muscarinic Antagonists; N-Methylscopolamine; Oxotremorine; Parasympatholytics; Pirenzepine; Radioligand Assay; Receptors, Muscarinic; Scopolamine; Scopolamine Derivatives; Trout	1995
Constitutive activation of chimeric m2/m5 muscarinic receptors and delineation of G-protein coupling selectivity domains. Biochemical pharmacology, 1996, Feb-23, Volume: 51, Issue:4 Topics: 3T3 Cells; Adenylyl Cyclases; Animals; Atropine; beta-Galactosidase; Binding, Competitive; Carbachol; Cell Division; Cell Line; Cell Transformation, Neoplastic; Chlorocebus aethiops; GTP-Binding Proteins; Humans; Kinetics; Mice; N-Methylscopolamine; Phosphatidylinositols; Receptors, Muscarinic; Recombinant Fusion Proteins; Scopolamine Derivatives; Signal Transduction; Transfection	1996
The role of the cholinergic system in the development of the human cerebellum. Brain research. Developmental brain research, 1995, Dec-21, Volume: 90, Issue:1-2 Topics: Acetylcholine; Atropine; Autoradiography; Binding, Competitive; Cerebellum; Choline O-Acetyltransferase; Embryonic and Fetal Development; Gestational Age; Humans; Immunohistochemistry; N-Methylscopolamine; Receptor, Nerve Growth Factor; Receptors, Muscarinic; Receptors, Nerve Growth Factor; Receptors, Nicotinic; Scopolamine Derivatives	1995
Suppression of the rat micturition reflex by imipramine. Journal of autonomic pharmacology, 1997, Volume: 17, Issue:1 Topics: Adrenergic Uptake Inhibitors; alpha-Methyltyrosine; Animals; Antidepressive Agents, Tricyclic; Atropine; Cholinergic Agents; Dose-Response Relationship, Drug; Drug Interactions; Enuresis; Enzyme Inhibitors; Female; Fenclonine; Hemicholinium 3; Imipramine; Injections, Intraperitoneal; Injections, Intravenous; Injections, Intraventricular; Methyltyrosines; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; N-Methylscopolamine; Parasympatholytics; Rats; Rats, Sprague-Dawley; Scopolamine Derivatives; Serotonin Agents; Urination	1997
Three allosteric modulators act at a common site, distinct from that of competitive antagonists, at muscarinic acetylcholine M2 receptors. The Journal of pharmacology and experimental therapeutics, 1997, Volume: 282, Issue:1 Topics: Alcuronium; Allosteric Regulation; Animals; Atropine; Female; Gallamine Triethiodide; Guinea Pigs; Male; Muscarinic Antagonists; N-Methylscopolamine; Receptor, Muscarinic M2; Receptors, Muscarinic; Scopolamine Derivatives	1997
Central cardiovascular effects of tacrine in the conscious dog: a role for catecholamines and vasopressin release. European journal of pharmacology, 1998, May-08, Volume: 348, Issue:2-3 Topics: Animals; Atropine; Blood Pressure; Bradycardia; Cholinesterase Inhibitors; Dogs; Dose-Response Relationship, Drug; Epinephrine; Female; Injections, Intravenous; Male; Muscarinic Antagonists; N-Methylscopolamine; Norepinephrine; Parasympathomimetics; Receptors, Muscarinic; Tacrine; Vasopressins	1998
Lithocholyltaurine interacts with cholinergic receptors on dispersed chief cells from guinea pig stomach. The American journal of physiology, 1998, Volume: 274, Issue:6 Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Atropine; Carbachol; Chief Cells, Gastric; Cholagogues and Choleretics; Cholecystokinin; Guinea Pigs; Male; N-Methylscopolamine; Parasympatholytics; Pepsinogens; Receptors, Cholinergic; Sincalide; Taurolithocholic Acid	1998
Carbachol-induced desensitization of PLC-beta pathway in rat myometrium: downregulation of Gqalpha/G11alpha. The American journal of physiology, 1998, Volume: 275, Issue:3 Topics: Aluminum Compounds; Animals; Atropine; Carbachol; Enzyme Inhibitors; Female; Fluorides; GTP-Binding Proteins; In Vitro Techniques; Indoles; Inositol; Inositol Phosphates; Isoenzymes; Kinetics; Membrane Potentials; Myometrium; N-Methylscopolamine; Phorbol 12,13-Dibutyrate; Phosphatidylinositols; Phospholipase C beta; Radioligand Assay; Rats; Rats, Wistar; Receptors, Muscarinic; Signal Transduction; Type C Phospholipases	1998
Mixed agonist-antagonist properties of clozapine at different human cloned muscarinic receptor subtypes expressed in Chinese hamster ovary cells. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 1999, Volume: 20, Issue:3 Topics: Animals; Antipsychotic Agents; Atropine; Binding Sites; Cell Membrane; CHO Cells; Cloning, Molecular; Clozapine; Cricetinae; Cyclic AMP; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Inositol Phosphates; Muscarinic Agonists; Muscarinic Antagonists; N-Methylscopolamine; Receptor, Muscarinic M1; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Receptors, Muscarinic; Sulfur Radioisotopes	1999
Autoantibodies against M2 muscarinic receptors in patients with cardiomyopathy display non-desensitized agonist-like effects. Life sciences, 1999, Volume: 64, Issue:6-7 Topics: Animals; Atropine; Autoantibodies; Binding Sites; Carbachol; Cardiomyopathy, Dilated; Cells, Cultured; Depression, Chemical; Dose-Response Relationship, Drug; Down-Regulation; Heart Rate; Humans; Muscarinic Agonists; Muscarinic Antagonists; Myocardium; N-Methylscopolamine; Rats; Rats, Wistar; Receptor, Muscarinic M2; Receptors, Muscarinic; Time Factors	1999
Pharmacological analysis of the novel mode of interaction between xanomeline and the M1 muscarinic acetylcholine receptor. The Journal of pharmacology and experimental therapeutics, 1999, Volume: 289, Issue:3 Topics: Animals; Atropine; Binding, Competitive; Carbachol; CHO Cells; Citrulline; Cricetinae; Humans; Kinetics; Muscarinic Agonists; N-Methylscopolamine; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Pirenzepine; Pyridines; Radioligand Assay; Receptor, Muscarinic M1; Receptors, Muscarinic; Recombinant Proteins; Thiadiazoles; Transfection; Tritium	1999
Alanine-scanning mutagenesis of transmembrane domain 6 of the M(1) muscarinic acetylcholine receptor suggests that Tyr381 plays key roles in receptor function. Molecular pharmacology, 1999, Volume: 56, Issue:5 Topics: Acetylcholine; Alanine; Animals; Atropine; Binding, Competitive; COS Cells; Immunohistochemistry; Ligands; Muscarinic Agonists; Muscarinic Antagonists; Mutagenesis, Site-Directed; N-Methylscopolamine; Oxotremorine; Phosphatidylinositols; Pilocarpine; Protein Structure, Tertiary; Quinuclidinyl Benzilate; Rats; Receptor, Muscarinic M1; Receptors, Muscarinic; Tyrosine	1999
Cloning and functional characterization of a Caenorhabditis elegans muscarinic acetylcholine receptor. Receptors & channels, 1999, Volume: 6, Issue:6 Topics: Acetylcholine; Amino Acid Sequence; Animals; Atropine; Base Sequence; Binding, Competitive; Caenorhabditis elegans; Chloride Channels; CHO Cells; Cloning, Molecular; Cricetinae; Gene Expression; Ion Channel Gating; Ligands; Molecular Sequence Data; N-Methylscopolamine; Oxotremorine; Receptors, Muscarinic; Recombinant Proteins; Scopolamine; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Xenopus	1999
Behavioral and neurochemical alterations after lithium-pilocarpine administration in young and adult rats: a comparative study. Pharmacology, biochemistry, and behavior, 2000, Volume: 65, Issue:3 Topics: Age Factors; Animals; Atropine; Behavior, Animal; Brain; Lithium; Male; N-Methylscopolamine; Pilocarpine; Rats; Rats, Wistar; Receptors, Dopamine; Receptors, Muscarinic; Spiperone	2000
The allosteric interaction of otenzepad (AF-DX 116) at muscarinic M2 receptors in guinea pig atria. European journal of pharmacology, 2001, Mar-30, Volume: 416, Issue:3 Topics: Acetylcholine; Allosteric Regulation; Animals; Atropine; Carbachol; Cardiotonic Agents; Dexetimide; Electric Stimulation; Female; Gallamine Triethiodide; Guinea Pigs; Heart Atria; In Vitro Techniques; Kinetics; Male; Muscarinic Antagonists; N-Methylscopolamine; Nicotinic Antagonists; Parasympatholytics; Phthalimides; Pirenzepine; Quaternary Ammonium Compounds; Radioligand Assay; Receptor, Muscarinic M2; Receptors, Muscarinic	2001
Central anticholinergics to treat nerve-agent poisoning. Lancet (London, England), 2002, Jan-19, Volume: 359, Issue:9302 Topics: Animals; Antidotes; Atropine; Central Nervous System Agents; Chemical Warfare Agents; Cholinergic Antagonists; Cholinesterase Inhibitors; Mice; N-Methylscopolamine; Physostigmine; Scopolamine	2002
Allosteric modulation by persistent binding of xanomeline of the interaction of competitive ligands with the M1 muscarinic acetylcholine receptor. The Journal of pharmacology and experimental therapeutics, 2002, Volume: 301, Issue:3 Topics: Allosteric Regulation; Animals; Atropine; Binding, Competitive; Buffers; CHO Cells; Cricetinae; Dose-Response Relationship, Drug; Humans; Kinetics; Ligands; Muscarinic Agonists; N-Methylscopolamine; Pyridines; Receptor, Muscarinic M1; Receptors, Muscarinic; Thiadiazoles; Tritium	2002
Intravenous atropine treatment in infantile hypertrophic pyloric stenosis. Archives of disease in childhood, 2003, Volume: 88, Issue:1 Topics: Atropine; Humans; Infant; Infant, Newborn; Infusions, Intravenous; Muscarinic Antagonists; N-Methylscopolamine; Pyloric Stenosis	2003
A comparison of some atropine-like drugs in man, with particular reference to their end-organ specificity. British journal of pharmacology and chemotherapy, 1958, Volume: 13, Issue:2 Topics: Accommodation, Ocular; Atropine; Heart Rate; Humans; Male; Methantheline; N-Methylscopolamine; Organ Specificity; Parasympatholytics; Propantheline; Pupil; Quaternary Ammonium Compounds; Salivation; Scopolamine; Sweating	1958
A G protein gamma subunit peptide stabilizes a novel muscarinic receptor state. Biochemical and biophysical research communications, 2006, Mar-24, Volume: 341, Issue:4 Topics: Acetylcholine; Animals; Atropine; Carbachol; CHO Cells; Cricetinae; Cricetulus; GTP-Binding Protein alpha Subunit, Gi2; N-Methylscopolamine; Peptide Fragments; Protein Prenylation; Quinuclidinyl Benzilate; Receptor, Muscarinic M2	2006
Function-specific blockage of M(1) and M(3) muscarinic acetylcholine receptors by VX and echothiophate. Brain research, 2006, Apr-26, Volume: 1085, Issue:1 Topics: Animals; Atropine; CHO Cells; Cholinesterase Inhibitors; Colforsin; Cricetinae; Cyclic AMP; Dose-Response Relationship, Drug; Drug Interactions; Echothiophate Iodide; Muscarinic Agonists; Muscarinic Antagonists; N-Methylscopolamine; Organothiophosphorus Compounds; Oxotremorine; Phosphatidylinositols; Protein Binding; Receptor, Muscarinic M1; Receptor, Muscarinic M3; Transfection; Tritium	2006
Long-term wash-resistant effects of brief interaction of xanomeline at the M1 muscarinic receptor. Neuroscience letters, 2006, Dec-13, Volume: 410, Issue:1 Topics: Animals; Atropine; Binding, Competitive; CHO Cells; Cricetinae; Cricetulus; Drug Interactions; Humans; Muscarinic Agonists; Muscarinic Antagonists; N-Methylscopolamine; Pyridines; Receptor, Muscarinic M1; Thiadiazoles; Time Factors; Transfection; Tritium	2006
Pharmacological characterization of a new antimuscarinic agent, solifenacin succinate, in comparison with other antimuscarinic agents. Biological & pharmaceutical bulletin, 2007, Volume: 30, Issue:1 Topics: Animals; Atropine; Benzhydryl Compounds; Benzilates; Benzofurans; Binding, Competitive; Carbachol; CHO Cells; Cholinergic Agonists; Cresols; Cricetinae; Cricetulus; Dose-Response Relationship, Drug; In Vitro Techniques; Male; Mandelic Acids; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; N-Methylscopolamine; Phenylpropanolamine; Pyrrolidines; Quinuclidines; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, Muscarinic; Solifenacin Succinate; Tetrahydroisoquinolines; Tolterodine Tartrate; Transfection; Urinary Bladder; Urinary Bladder, Overactive; Urination	2007
Allosteric interaction of the neuromuscular blockers vecuronium and pancuronium with recombinant human muscarinic M2 receptors. European journal of pharmacology, 2007, Aug-13, Volume: 569, Issue:1-2 Topics: Allosteric Regulation; Animals; Atropine; Binding, Competitive; CHO Cells; Cricetinae; Cricetulus; Gallamine Triethiodide; Humans; Kinetics; Muscarinic Antagonists; N-Methylscopolamine; Neuromuscular Blocking Agents; Pancuronium; Radioligand Assay; Receptor, Muscarinic M2; Recombinant Proteins; Tritium; Vecuronium Bromide	2007
The impact of orthosteric radioligand depletion on the quantification of allosteric modulator interactions. The Journal of pharmacology and experimental therapeutics, 2008, Volume: 325, Issue:3 Topics: Alcuronium; Allosteric Regulation; Animals; Atropine; Carbachol; Cell Membrane; CHO Cells; Cricetinae; Cricetulus; Gallamine Triethiodide; Ligands; Models, Biological; N-Methylscopolamine; Radioligand Assay; Receptor, Muscarinic M2; Tritium	2008
Bronchodilatory effects of S-isopetasin, an antimuscarinic sesquiterpene of Petasites formosanus, on obstructive airway hyperresponsiveness. European journal of pharmacology, 2008, Apr-28, Volume: 584, Issue:2-3 Topics: Acetylcholine; Animals; Atropine; Binding, Competitive; Bronchial Hyperreactivity; Bronchoconstrictor Agents; Bronchodilator Agents; Cells, Cultured; Cholinesterase Inhibitors; Diamines; Dose-Response Relationship, Drug; Guinea Pigs; Humans; Ipratropium; Male; Muscarinic Antagonists; Muscle, Smooth; N-Methylscopolamine; Neostigmine; Petasites; Piperidines; Protein Binding; Receptor, Muscarinic M3; Sesquiterpenes; Time Factors; Trachea	2008
Mechanisms of M3 muscarinic receptor regulation by wash-resistant xanomeline binding. Pharmacology, 2009, Volume: 83, Issue:5 Topics: Animals; Atropine; Binding Sites; Carbachol; Cell Line, Transformed; Cricetinae; Drug Interactions; Female; GTP-Binding Protein alpha Subunits, Gq-G11; Humans; Muscarinic Agonists; N-Methylscopolamine; Phosphatidylinositols; Pilocarpine; Pyridines; Quinuclidinyl Benzilate; Receptor, Muscarinic M3; Thiadiazoles; Time Factors; Transfection	2009
Detection of novel functional selectivity at M3 muscarinic acetylcholine receptors using a Saccharomyces cerevisiae platform. ACS chemical biology, 2010, Apr-16, Volume: 5, Issue:4 Topics: 3T3 Cells; Animals; Atropine; Gene Expression; Genes, Reporter; GTP-Binding Protein alpha Subunits; GTP-Binding Protein alpha Subunits, Gq-G11; Humans; Mice; Muscarinic Antagonists; N-Methylscopolamine; Pirenzepine; Receptor, Muscarinic M3; Recombinant Fusion Proteins; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins	2010
Assessment of novel muscarinic acetylcholine receptors in rat cerebral cortex by a tissue segment binding method. Journal of pharmacological sciences, 2010, Volume: 112, Issue:4 Topics: Acetylcholine; Animals; Atropine; Cerebral Cortex; In Vitro Techniques; Male; N-Methylscopolamine; Quinuclidinyl Benzilate; Radioligand Assay; Rats; Rats, Wistar; Receptors, Muscarinic	2010
Intracellular distribution of functional M(1) -muscarinic acetylcholine receptors in N1E-115 neuroblastoma cells. Journal of neurochemistry, 2011, Volume: 118, Issue:6 Topics: Animals; Atropine; Blotting, Western; Calcium; Carbachol; Cell Line, Tumor; Elapid Venoms; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Immunohistochemistry; Inositol Phosphates; Kinetics; Mice; Muscarinic Agonists; Muscarinic Antagonists; N-Methylscopolamine; Neuroblastoma; Peptides, Cyclic; Pirenzepine; Protein Kinase Inhibitors; Quinuclidinyl Benzilate; Receptor, Muscarinic M1; Receptors, Cell Surface	2011
M1 is a major subtype of muscarinic acetylcholine receptors on mouse colonic epithelial cells. Journal of gastroenterology, 2013, Volume: 48, Issue:8 Topics: Animals; Atropine; Benzofurans; Colitis; Colon; Elapid Venoms; Epithelial Cells; Inflammation; Intestinal Mucosa; Male; Mice; Mice, Inbred BALB C; N-Methylscopolamine; Parasympatholytics; Pyrrolidines; Radioligand Assay; Receptor, Muscarinic M1; Receptor, Muscarinic M3	2013
Sudden unexpected death in a mouse model of Dravet syndrome. The Journal of clinical investigation, 2013, Volume: 123, Issue:4 Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atrioventricular Block; Atropine; Bradycardia; Disease Models, Animal; Epilepsies, Myoclonic; Epilepsy, Tonic-Clonic; Heart Rate; Humans; Mice; Mice, Knockout; N-Methylscopolamine; NAV1.1 Voltage-Gated Sodium Channel; Parasympatholytics	2013
Comparison of subcellular distribution and functions between exogenous and endogenous M1 muscarinic acetylcholine receptors. Life sciences, 2013, Jul-19, Volume: 93, Issue:1 Topics: Analysis of Variance; Animals; Atropine; Blotting, Western; Calcium; CHO Cells; Cricetinae; Cricetulus; Mice; Microscopy, Confocal; N-Methylscopolamine; Organelles; Pirenzepine; Quinuclidinyl Benzilate; Radioligand Assay; Receptor, Muscarinic M1; Recombinant Proteins; Tritium	2013