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n-methylprotoporphyrin ix and heme

n-methylprotoporphyrin ix has been researched along with heme in 14 studies

Compound Research Comparison

Studies
(n-methylprotoporphyrin ix)
Trials
(n-methylprotoporphyrin ix)
Recent Studies (post-2010)
(n-methylprotoporphyrin ix)
Studies
(heme)
Trials
(heme)
Recent Studies (post-2010) (heme)
320419,0861154,781

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19904 (28.57)18.7374
1990's0 (0.00)18.2507
2000's7 (50.00)29.6817
2010's3 (21.43)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Dailey, HA; Fadigan, A1
De Matteis, F; Marks, GS1
Dailey, HA; Fleming, JE1
de Matteis, F; de Sa, N; Gibbs, AH; Hollands, C; Rizzardini, M1
Franklin Bunn, H; Horiguchi, H1
Correia, MA; Han, XM; Hefner, C; Lee, G; Maher, JJ1
Earley, KW; Feissner, RE; Frawley, ER; Kranz, RG; Loughman, JA; Richard-Fogal, CL1
Feissner, RE; Frawley, ER; Kranz, RG; Richard-Fogal, CL1
Correia, MA; Hefner, C; Liao, M; Maher, JJ; Maltby, DA; Medzihradszky, KF; Pabarcus, MK; Salas-Castillo, SP; Wang, Y; Yan, J1
Arosio, P; Finazzi, D; Gatta, LB; Verardi, R; Vitali, M1
Bickar, D; Guenthner, CJ; Harrington, ME1
Hakkola, J; Lämsä, V; Levonen, AL; Sormunen, R; Yamamoto, M1
Burgio, G; David, P; Deybach, JC; Foote, SJ; Goodman, CD; Gouya, L; Jerkovic, A; Manceau, H; McFadden, GI; McMorran, BJ; Mercereau-Puijalon, O; Puy, H; Smith, CM; Sturm, A; van Dooren, G; Winship, I1
Adachi, Y; Fujisawa, JI; Izawa, S; Ohnishi, K; Sasai, M; Takeda, TA; Taketani, S1

Other Studies

14 other study(ies) available for n-methylprotoporphyrin ix and heme

ArticleYear
Inhibition of ferrochelatase during differentiation of murine erythroleukaemia cells.
    The Biochemical journal, 1987, Apr-15, Volume: 243, Issue:2

    Topics: Animals; Cations, Divalent; Cell Differentiation; Dicarbethoxydihydrocollidine; Dimethyl Sulfoxide; Ferrochelatase; Heme; Leukemia, Erythroblastic, Acute; Lyases; Mice; Organometallic Compounds; Protoporphyrins

1987
The effect of N-methylprotoporphyrin and succinyl-acetone on the regulation of heme biosynthesis in chicken hepatocytes in culture.
    FEBS letters, 1983, Aug-08, Volume: 159, Issue:1-2

    Topics: 5-Aminolevulinate Synthetase; Animals; Chick Embryo; Ferrochelatase; Heme; Heptanoates; Heptanoic Acids; Liver; Phenobarbital; Porphyrins; Protoporphyrins

1983
Bovine ferrochelatase. Kinetic analysis of inhibition by N-methylprotoporphyrin, manganese, and heme.
    The Journal of biological chemistry, 1983, Oct-10, Volume: 258, Issue:19

    Topics: Animals; Cattle; Ferrochelatase; Heme; Kinetics; Lyases; Manganese; Mitochondria, Liver; Molecular Weight; Porphyrins; Protoporphyrins; Structure-Activity Relationship

1983
Inactivation of cytochrome P-450 and production of N-alkylated porphyrins caused in isolated hepatocytes by substituted dihydropyridines. Structural requirements for loss of haem and alkylation of the pyrrole nitrogen atom.
    FEBS letters, 1982, Aug-16, Volume: 145, Issue:1

    Topics: Animals; Cytochrome P-450 Enzyme Inhibitors; Dicarbethoxydihydrocollidine; Ferrochelatase; Heme; Liver; Male; Mice; Mitochondria, Liver; Porphyrins; Protoporphyrins; Structure-Activity Relationship

1982
Erythropoietin induction in Hep3B cells is not affected by inhibition of heme biosynthesis.
    Biochimica et biophysica acta, 2000, Feb-28, Volume: 1495, Issue:3

    Topics: Cell Survival; Deferoxamine; Enzyme Inhibitors; Erythropoietin; Heme; Heptanoates; Humans; Isoniazid; Protoporphyrins; Tumor Cells, Cultured

2000
Heme-reversible impairment of CYP2B1/2 induction in heme-depleted rat hepatocytes in primary culture: translational control by a hepatic alpha-subunit of the eukaryotic initiation factor kinase?
    The Journal of pharmacology and experimental therapeutics, 2005, Volume: 314, Issue:1

    Topics: Aminolevulinic Acid; Animals; Aryl Hydrocarbon Hydroxylases; Cells, Cultured; Cytochrome P-450 CYP2B1; eIF-2 Kinase; Enzyme Induction; Heat-Shock Proteins; Heme; Hepatocytes; Molecular Chaperones; Peptide Elongation Factor 2; Phenobarbital; Phosphorylation; Proteins; Protoporphyrins; Pyrimethamine; Rats; Steroid Hydroxylases; Transcriptional Activation

2005
Recombinant cytochromes c biogenesis systems I and II and analysis of haem delivery pathways in Escherichia coli.
    Molecular microbiology, 2006, Volume: 60, Issue:3

    Topics: Amino Acid Sequence; Bordetella pertussis; Cytochrome c Group; Cytochromes c1; Cytochromes c2; Escherichia coli; Escherichia coli Proteins; Ferrochelatase; Gene Expression Regulation, Bacterial; Heme; Molecular Sequence Data; Protoporphyrins; Recombinant Proteins

2006
Heme concentration dependence and metalloporphyrin inhibition of the system I and II cytochrome c assembly pathways.
    Journal of bacteriology, 2007, Volume: 189, Issue:2

    Topics: Cytochrome c Group; Escherichia coli; Escherichia coli Proteins; Gene Expression Regulation, Bacterial; Heme; Metalloporphyrins; Models, Biological; Mutation; Protoporphyrins; Signal Transduction

2007
Impaired dexamethasone-mediated induction of tryptophan 2,3-dioxygenase in heme-deficient rat hepatocytes: translational control by a hepatic eIF2alpha kinase, the heme-regulated inhibitor.
    The Journal of pharmacology and experimental therapeutics, 2007, Volume: 323, Issue:3

    Topics: Animals; Cells, Cultured; Chromatography, Liquid; Cloning, Molecular; Dexamethasone; eIF-2 Kinase; Electrophoresis, Polyacrylamide Gel; Enzyme Induction; Escherichia coli; Glucocorticoids; Heme; Hepatocytes; Male; Protein Biosynthesis; Protoporphyrins; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Tandem Mass Spectrometry; Tryptophan Oxygenase

2007
Inhibition of heme synthesis alters Amyloid Precursor Protein processing.
    Journal of neural transmission (Vienna, Austria : 1996), 2009, Volume: 116, Issue:1

    Topics: ADAM Proteins; ADAM10 Protein; ADAM17 Protein; Adenosine Triphosphate; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Cell Count; Cell Differentiation; Cell Line; Electron Transport Complex IV; Enzyme Inhibitors; Ferrochelatase; Heme; Humans; Membrane Proteins; Neuroblastoma; Peptide Fragments; Physiological Phenomena; Protein Carbonylation; Protoporphyrins; RNA, Messenger; RNA, Small Interfering; Signal Transduction; Transfection

2009
Heme reversibly damps PERIOD2 rhythms in mouse suprachiasmatic nucleus explants.
    Neuroscience, 2009, Dec-01, Volume: 164, Issue:2

    Topics: Animals; Central Nervous System Agents; Circadian Rhythm; Esophagus; Female; Gene Knock-In Techniques; Heme; Heme Oxygenase (Decyclizing); Hemin; In Vitro Techniques; Luciferases; Male; Mice; Mice, Transgenic; Period Circadian Proteins; Periodicity; Protoporphyrins; Spleen; Suprachiasmatic Nucleus; Thymus Gland

2009
Heme and heme biosynthesis intermediates induce heme oxygenase-1 and cytochrome P450 2A5, enzymes with putative sequential roles in heme and bilirubin metabolism: different requirement for transcription factor nuclear factor erythroid- derived 2-like 2.
    Toxicological sciences : an official journal of the Society of Toxicology, 2012, Volume: 130, Issue:1

    Topics: Animals; Aryl Hydrocarbon Hydroxylases; Bilirubin; Cytochrome P-450 CYP2A6; Cytochrome P450 Family 2; Endoplasmic Reticulum; Enzyme Induction; Gene Expression Regulation, Enzymologic; Heme; Heme Oxygenase-1; Hemin; Hepatocytes; Heptanoates; Homeostasis; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mitochondria; NF-E2-Related Factor 2; Protoporphyrins

2012
Red cells from ferrochelatase-deficient erythropoietic protoporphyria patients are resistant to growth of malarial parasites.
    Blood, 2015, Jan-15, Volume: 125, Issue:3

    Topics: Animals; Erythrocytes; Female; Ferrochelatase; Heme; Humans; Malaria, Falciparum; Male; Mice; Mice, Inbred C57BL; Phenotype; Plasmodium berghei; Protoporphyria, Erythropoietic; Protoporphyrins

2015
Potential role of heme metabolism in the inducible expression of heme oxygenase-1.
    Biochimica et biophysica acta. General subjects, 2017, Volume: 1861, Issue:7

    Topics: Arsenites; Basic-Leucine Zipper Transcription Factors; Carbon Monoxide; Enzyme Induction; Fanconi Anemia Complementation Group Proteins; HEK293 Cells; HeLa Cells; Heme; Heme Oxygenase-1; Heptanoates; Humans; Isothiocyanates; Protoporphyrins; Sodium Compounds; Sulfoxides

2017