Compounds > n-methylisoindigotin
Page last updated: 2024-09-03

n-methylisoindigotin and indirubin

n-methylisoindigotin has been researched along with indirubin in 5 studies

Compound Research Comparison

Studies
(n-methylisoindigotin)		Trials
(n-methylisoindigotin)		Recent Studies (post-2010)
(n-methylisoindigotin)		Studies
(indirubin)		Trials
(indirubin)		Recent Studies (post-2010) (indirubin)
340113473184

Protein Interaction Comparison

ProteinTaxonomyn-methylisoindigotin (IC50)indirubin (IC50)
Glycogen synthase kinase-3 beta Sus scrofa (pig)1
[Tau protein] kinase Sus scrofa (pig)1
Cyclin-dependent kinase 14Homo sapiens (human)2.2
G2/mitotic-specific cyclin-B2Homo sapiens (human)8.25
Epidermal growth factor receptorHomo sapiens (human)2
Insulin receptorHomo sapiens (human)2
Cyclin-dependent kinase 1Homo sapiens (human)7.74
Cyclin-dependent kinase 4Homo sapiens (human)2.2
G2/mitotic-specific cyclin-B1Homo sapiens (human)8.8333
G2/mitotic-specific cyclin-BMarthasterias glacialis (spiny starfish)1
Cyclin-A2Homo sapiens (human)3.525
Cyclin-dependent kinase 11BHomo sapiens (human)2.2
Kit ligandHomo sapiens (human)2
G1/S-specific cyclin-E1Homo sapiens (human)4.85
Cyclin-dependent kinase 2Homo sapiens (human)3.24
Vascular endothelial growth factor receptor 2Homo sapiens (human)2
Cyclin-dependent kinase 8Homo sapiens (human)2.2
Glycogen synthase kinase-3 alphaHomo sapiens (human)1.5
Glycogen synthase kinase-3 betaHomo sapiens (human)0.8515
Cyclin-dependent kinase 7Homo sapiens (human)2.2
Cyclin-dependent kinase 9Homo sapiens (human)2.2
Cyclin-dependent kinase 3Homo sapiens (human)2.2
Cyclin-dependent kinase 6Homo sapiens (human)2.2
Cyclin-dependent-like kinase 5 Homo sapiens (human)6.15
Cyclin-dependent kinase 16Homo sapiens (human)2.2
Cyclin-dependent kinase 17Homo sapiens (human)2.2
Cyclin-dependent kinase 18Homo sapiens (human)2.2
Cyclin-dependent kinase 13Homo sapiens (human)2.2
Cyclin-dependent kinase 5 activator 1Homo sapiens (human)6.7143
Cyclin-dependent kinase 10Homo sapiens (human)2.2
Cyclin-dependent kinase 20Homo sapiens (human)2.2
G2/mitotic-specific cyclin-B3Homo sapiens (human)8.25
Cyclin-dependent kinase 15Homo sapiens (human)2.2
Cyclin-dependent kinase 19Homo sapiens (human)2.2
Cyclin-dependent kinase 1Oryzias latipes (Japanese medaka)1
Cyclin-dependent kinase 12Homo sapiens (human)2.2

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19901 (20.00)18.7374
1990's1 (20.00)18.2507
2000's1 (20.00)29.6817
2010's2 (40.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chen, RH; Ji, XJ; Li, K; Liu, XM; Wang, LG1
Gao, BH; Liu, JZ; Wu, GY1
Hao, Y; Liu, B; Qian, L; Xiao, Z1
Chen, F; Hou, M; Ji, C; Li, L; Ma, D; Sun, J; Yan, S; Zhang, M1
Deng, X; Gao, Q; Gao, X; Gu, L; Wang, Q; Wang, Y; Xiong, X; Ye, B; Zeng, Z1

Reviews

1 review(s) available for n-methylisoindigotin and indirubin

ArticleYear
Indirubin and meisoindigo in the treatment of chronic myelogenous leukemia in China.
    Leukemia & lymphoma, 2002, Volume: 43, Issue:9

    Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Blast Crisis; China; Dose-Response Relationship, Drug; Humans; Hydroxyurea; Indoles; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Mice; Models, Chemical; Time Factors; Treatment Outcome

2002

Other Studies

4 other study(ies) available for n-methylisoindigotin and indirubin

ArticleYear
Pharmacological studies of meisoindigo: absorption and mechanism of action.
    Biomedical and environmental sciences : BES, 1991, Volume: 4, Issue:3

    Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Indoles; Rats

1991
[Studies on the mechanism of antitumor action of Dian III].
    Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae, 1984, Volume: 6, Issue:6

    Topics: Animals; Antineoplastic Agents; DNA; Indoles; Kinetics; Mice; Rats; Thymidine; Uridine

1984
Imatinib achieved complete cytogenetic response in a CML patient received 32-year indirubin and its derivative treatment.
    Leukemia research, 2010, Volume: 34, Issue:2

    Topics: Adult; Benzamides; Cytogenetic Analysis; Humans; Imatinib Mesylate; Indoles; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Male; Neoplasm, Residual; Philadelphia Chromosome; Piperazines; Pyrimidines; Remission Induction

2010
Meisoindigo, but not its core chemical structure indirubin, inhibits zebrafish interstitial leukocyte chemotactic migration.
    Pharmaceutical biology, 2017, Volume: 55, Issue:1

    Topics: Animals; Animals, Genetically Modified; Anti-Inflammatory Agents; Chemotaxis, Leukocyte; Disease Models, Animal; Dose-Response Relationship, Drug; Green Fluorescent Proteins; Indoles; Inflammation; Leukocytes; Molecular Structure; Signal Transduction; Structure-Activity Relationship; Time Factors; Zebrafish

2017