n-methylcytisine has been researched along with anagyrine* in 2 studies
1 review(s) available for n-methylcytisine and anagyrine
| Article | Year |
|---|---|
Primary constituents of blue cohosh: quantification in dietary supplements and potential for toxicity.
Dietary supplements containing dried roots or extracts of the roots and/or rhizomes of blue cohosh (Caulophyllum thalictroides) are widely available. This botanical has a long history of use by Native Americans and its use continues to the present day. The primary constituents of blue cohosh are its alkaloids and saponins. The structures of the alkaloids magnoflorine, baptifoline, anagyrine, and N-methylcytisine have been known for many years. The last 10 years have seen a great increase in isolation and identification of the large number of saponins present in blue cohosh. Important developments in nuclear magnetic resonance techniques have contributed substantially to the increase in elucidation of the structures of the complex saponins. Several authors have described quantitative methods for both the alkaloids and saponins in blue cohosh. Such methods have made it possible to quantify these constituents in dietary supplements containing this botanical ingredient. Concentrations of both alkaloids and saponins vary substantially in dietary supplements of blue cohosh. The nicotinic alkaloid, N-methylcytisine, a potent toxicant, has been found in all dietary supplements of blue cohosh analyzed. The teratogenic alkaloid anagyrine has been found in some but not all dietary supplements. Topics: Alkaloids; Azocines; Caulophyllum; Chromatography, High Pressure Liquid; Chromatography, Liquid; Dietary Supplements; Female; Humans; Plant Extracts; Plant Roots; Pregnancy; Quinolizines; Reference Standards; Rhizome; Saponins | 2013 |
1 other study(ies) available for n-methylcytisine and anagyrine
| Article | Year |
|---|---|
Analysis of aporphine and quinolizidine alkaloids from Caulophyllum thalictroides by densitometry and HPLC.
High-performance liquid chromatographic (HPLC) and densitometry procedures were developed to determine the principal alkaloids in the roots of C. thalictroides. In both techniques the alkaloids content was assessed using cytisine as an internal standard. The purity and identity of the peaks of the alkaloids was examined by diode array detection and by comparison with the standards. The content of individual alkaloids was found to be in the range 0.02-1.1% w/w. Topics: Alkaloids; Apomorphine; Aporphines; Azocines; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Densitometry; Molecular Structure; Pyridines; Quinolizines; Reproducibility of Results; Time Factors | 1997 |