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n-methylcolchiceinamide, (s)-isomer and colchicine

n-methylcolchiceinamide, (s)-isomer has been researched along with colchicine in 7 studies

*Colchicine: A major alkaloid from Colchicum autumnale L. and found also in other Colchicum species. Its primary therapeutic use is in the treatment of gout, but it has been used also in the therapy of familial Mediterranean fever (PERIODIC DISEASE). [MeSH]

*Colchicine: A major alkaloid from Colchicum autumnale L. and found also in other Colchicum species. Its primary therapeutic use is in the treatment of gout, but it has been used also in the therapy of familial Mediterranean fever (PERIODIC DISEASE). [MeSH]

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19903 (42.86)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's4 (57.14)2.80

Authors

AuthorsStudies
Brossi, A; Chignell, CF; Dumont, R; Quinn, FR; Suffness, M1
Beisler, JA; Neiman, Z; Quinn, FR1
Beisler, JA; Quinn, FR1
Al-Bajalan, HM; Alali, FQ; Chong, KF; Ghawanmeh, AA; Mackeen, MM1
Beletskaya, IP; Fedorov, AY; Gracheva, IA; Schmalz, HG; Shchegravina, ES1
Aminpour, M; Huczyński, A; Janczak, J; Krzywik, J; Maj, E; Moshari, M; Mozga, W; Tuszyński, JA; Wietrzyk, J1
Huczyński, A; Krzywik, J; Maj, E; Mozga, W; Nasulewicz-Goldeman, A; Wietrzyk, J1

Reviews

2 review(s) available for n-methylcolchiceinamide, (s)-isomer and colchicine

ArticleYear
Recent developments on (-)-colchicine derivatives: Synthesis and structure-activity relationship.
    European journal of medicinal chemistry, 2020, Jan-01, Volume: 185

    Topics: Antineoplastic Agents, Phytogenic; Cell Proliferation; Colchicine; Humans; Molecular Structure; Neoplasms

2020
Colchicine Alkaloids and Synthetic Analogues: Current Progress and Perspectives.
    Journal of medicinal chemistry, 2020, 10-08, Volume: 63, Issue:19

    Topics: Alkaloids; Binding Sites; Colchicine; Polymerization; Structure-Activity Relationship; Tubulin

2020

Other Studies

5 other study(ies) available for n-methylcolchiceinamide, (s)-isomer and colchicine

ArticleYear
A novel synthesis of colchicide and analogues from thiocolchicine and congeners: reevaluation of colchicide as a potential antitumor agent.
    Journal of medicinal chemistry, 1987, Volume: 30, Issue:4

    Topics: Animals; Antineoplastic Agents; Colchicine; Mice; Neoplasms, Experimental; Structure-Activity Relationship; Tubulin

1987
Toxicity quantitative structure--activity relationships of colchicines.
    Journal of medicinal chemistry, 1981, Volume: 24, Issue:5

    Topics: Animals; Chemical Phenomena; Chemistry; Colchicine; Lethal Dose 50; Mice; Structure-Activity Relationship

1981
Quantitative structure-activity relationships of colchicines against P388 leukemia in mice.
    Journal of medicinal chemistry, 1981, Volume: 24, Issue:3

    Topics: Animals; Colchicine; Leukemia P388; Leukemia, Experimental; Mathematics; Mice; Structure-Activity Relationship

1981
An insight into the anticancer potential of carbamates and thiocarbamates of 10-demethoxy-10-methylaminocolchicine.
    European journal of medicinal chemistry, 2021, Apr-05, Volume: 215

    Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Colchicine; Drug Screening Assays, Antitumor; Humans; Molecular Docking Simulation; Molecular Structure; Protein Binding; Quantitative Structure-Activity Relationship; Thiocarbamates; Tubulin; Tubulin Modulators

2021
Synthesis and antiproliferative screening of novel doubly modified colchicines containing urea, thiourea and guanidine moieties.
    Bioorganic & medicinal chemistry letters, 2021, 09-01, Volume: 47

    Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Colchicine; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Guanidine; Humans; Molecular Structure; Structure-Activity Relationship; Thiourea; Urea

2021