n-methylaspartate has been researched along with valproic acid in 25 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (8.00) | 18.7374 |
| 1990's | 9 (36.00) | 18.2507 |
| 2000's | 5 (20.00) | 29.6817 |
| 2010's | 6 (24.00) | 24.3611 |
| 2020's | 3 (12.00) | 2.80 |
| Authors | Studies |
|---|---|
| Baron, BM; Dudley, MW; Kane, JM; Miller, FP; Sorensen, SM; Staeger, MA | 1 |
| Kasparow, S; Zeise, ML; Zieglgänsberger, W | 1 |
| Czuczwar, SJ; Janusz, W; Kleinrok, Z; Wamil, A | 1 |
| Kapetanovic, IM; Kupferberg, HJ; Torchin, CD; Yonekawa, WD | 1 |
| Löscher, W | 1 |
| Davies, JA | 1 |
| Czuczwar, SJ; Kleinrok, Z; Turski, WA; Tutka, P | 1 |
| Brown-Croyts, LM; Ko, GY; Teyler, TJ | 1 |
| Andersen, PH; Burns, CM; Chang, H; Crider, AM; el-Assadi, AA; Hinko, CN; Ho, B; Kliem, MA; Klitgaard, H; Seo, TH; Steinmiller, CL; Tietz, EI; Venkatarangan, P | 1 |
| Kábová, R; Liptáková, S; Pometlová, M; Slamberová, R; Velísek, L | 1 |
| Czuczwar, SJ; Haberek, G; Kleinrok, Z; Matyska, J; Pilip, S; Tomczyk, T; Turski, WA; Urbanska, EM | 1 |
| Diependaele, G; Govaerts, SJ; Lambert, DM; Robert, AR; Vandevoorde, S | 1 |
| Bown, CD; Wang, JF; Young, LT | 1 |
| Chuang, DM | 1 |
| Gobbi, G; Janiri, L | 1 |
| Basselin, M; Bell, JM; Chang, L; Chen, M; Rapoport, SI | 1 |
| Kubová, H; Mares, P | 1 |
| Brutsche, NE; Diazgranados, N; Ibrahim, L; Kammerer, WA; Khalife, S; Kronstein, P; Luckenbaugh, DA; Machado-Vieira, R; Manji, HK; Newberg, A; Quezado, Z; Salvadore, G; Zarate, CA | 1 |
| Desai, NS; Higgins, EA; Walcott, EC | 1 |
| Guo, X; Harada, C; Harada, T; Kimura, A; Namekata, K; Noro, T | 1 |
| Biber, K; Masuch, A; Shieh, CH; van Calker, D; van Rooijen, N | 1 |
| Franke, H; Illes, P; Khan, MT; Liu, J; Nerlich, J; Tang, Y | 1 |
| Hayashi, D; Miyazaki, Y; Okubo, T; Suzuki, T; Takizawa, T; Tanaka, K; Usami, M | 1 |
| Fu, L; Jin, Z; Liu, S; Niu, W; Niu, Y; Ren, J; Tian, H; Xie, L; Yao, Z; Yu, C | 1 |
| Bhatia, A; Joshi, R; Kaur, G; Kumar, R; Medhi, B; Mishra, A; Prajapat, M; Sarma, P; Sharma, A; Singla, R | 1 |
3 review(s) available for n-methylaspartate and valproic acid
| Article | Year |
|---|---|
Effects of the antiepileptic drug valproate on metabolism and function of inhibitory and excitatory amino acids in the brain.
Topics: Amino Acids; Animals; Anticonvulsants; Brain; gamma-Aminobutyric Acid; Humans; N-Methylaspartate; Neurotransmitter Agents; Valproic Acid | 1993 |
Mechanisms of action of antiepileptic drugs.
Topics: Acetates; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Epilepsy; GABA Antagonists; Gabapentin; gamma-Aminobutyric Acid; Humans; N-Methylaspartate; Neural Pathways; Receptors, GABA; Receptors, N-Methyl-D-Aspartate; Valproic Acid | 1995 |
The antiapoptotic actions of mood stabilizers: molecular mechanisms and therapeutic potentials.
Topics: Affect; Animals; Antimanic Agents; Apoptosis; Excitatory Amino Acid Agonists; Humans; Lithium; N-Methylaspartate; Rats; Stroke; Valproic Acid | 2005 |
1 trial(s) available for n-methylaspartate and valproic acid
| Article | Year |
|---|---|
A randomized add-on trial of an N-methyl-D-aspartate antagonist in treatment-resistant bipolar depression.
Topics: Adolescent; Adult; Aged; Bipolar Disorder; Diagnostic and Statistical Manual of Mental Disorders; Double-Blind Method; Drug Resistance; Drug Therapy, Combination; Excitatory Amino Acid Antagonists; Female; Humans; Ketamine; Lithium Compounds; Male; Middle Aged; N-Methylaspartate; Placebos; Psychiatric Status Rating Scales; Treatment Outcome; Valproic Acid | 2010 |
21 other study(ies) available for n-methylaspartate and valproic acid
| Article | Year |
|---|---|
2,4-Dihydro-3H-1,2,4-triazol-3-ones as anticonvulsant agents.
Topics: Animals; Anticonvulsants; Chemical Phenomena; Chemistry, Physical; Gerbillinae; Hippocampus; Hypoxia; Male; Mice; Neurons; Phencyclidine; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Triazoles | 1990 |
Valproate suppresses N-methyl-D-aspartate-evoked, transient depolarizations in the rat neocortex in vitro.
Topics: Animals; Diencephalon; Glutamates; In Vitro Techniques; Membrane Potentials; N-Methylaspartate; Rats; Rats, Inbred Strains; Synapses; Telencephalon; Valproic Acid | 1991 |
Inhibition of aminophylline-induced convulsions in mice by antiepileptic drugs and other agents.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Aminophylline; Animals; Anticonvulsants; Aspartic Acid; Diazepam; Female; Mice; N-Methylaspartate; Phenobarbital; Seizures; Synaptic Transmission; Valproic Acid | 1987 |
Effects of pharmacological manipulations on basal and newly synthesized levels of GABA, glutamate, aspartate and glutamine in mouse brain cortex.
Topics: 2-Amino-5-phosphonovalerate; 3-Mercaptopropionic Acid; Amino Acids; Animals; Aspartic Acid; Cerebral Cortex; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glutamine; Male; Mice; N-Methylaspartate; Valproic Acid | 1988 |
Influence of aminophylline and strychnine on the protective activity of excitatory amino acid antagonists against maximal electroshock-induced convulsions in mice.
Topics: Aminophylline; Animals; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Convulsants; Electroshock; Excitatory Amino Acid Antagonists; Male; Mice; N-Methylaspartate; Phosphodiesterase Inhibitors; Piperazines; Seizures; Strychnine; Valproic Acid | 1996 |
The effects of anticonvulsant drugs on NMDA-EPSP, AMPA-EPSP, and GABA-IPSP in the rat hippocampus.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anticonvulsants; Electrophysiology; gamma-Aminobutyric Acid; Hippocampus; Male; N-Methylaspartate; Phenobarbital; Phenytoin; Rats; Rats, Inbred Strains; Valproic Acid | 1997 |
Anticonvulsant activity of novel derivatives of 2- and 3-piperidinecarboxylic acid in mice and rats.
Topics: 4-Aminopyridine; Amygdala; Animals; Anticonvulsants; Brain; Convulsants; Kindling, Neurologic; Male; Mice; Mice, Inbred Strains; Molecular Structure; N-Methylaspartate; Neurotoxins; Nipecotic Acids; Pentylenetetrazole; Pipecolic Acids; Proline; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Receptors, Phencyclidine; Seizures; Structure-Activity Relationship; Valproic Acid | 1996 |
Age-specific N-methyl-D-aspartate-induced seizures: perspectives for the West syndrome model.
Topics: Age Factors; Animals; Behavior, Animal; Disease Models, Animal; Electroencephalography; Humans; Hydrocortisone; N-Methylaspartate; Pyridoxine; Rats; Seizures; Spasms, Infantile; Valproic Acid | 1999 |
NMDA- but not kainate-mediated events reduce efficacy of some antiepileptic drugs against generalized tonic-clonic seizures in mice.
Topics: Animals; Anticonvulsants; Carbamazepine; Diazepam; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Electroshock; Epilepsy, Tonic-Clonic; Kainic Acid; Male; Mice; N-Methylaspartate; Phenobarbital; Phenytoin; Receptors, N-Methyl-D-Aspartate; Valproic Acid | 1999 |
Anticonvulsant activity of N-palmitoylethanolamide, a putative endocannabinoid, in mice.
Topics: Amides; Animals; Anticonvulsants; Cannabinoid Receptor Modulators; Cannabinoids; Convulsants; Disease Models, Animal; Dose-Response Relationship, Drug; Electroshock; Endocannabinoids; Ethanolamines; Male; Mice; N-Methylaspartate; Palmitic Acids; Propionates; Seizures; Valproic Acid | 2001 |
Attenuation of N-methyl-D-aspartate-mediated cytoplasmic vacuolization in primary rat hippocampal neurons by mood stabilizers.
Topics: Animals; Antimanic Agents; Bipolar Disorder; Carbamazepine; Cell Survival; Cells, Cultured; Cytoplasm; Drug Interactions; Fetus; Glial Fibrillary Acidic Protein; Hippocampus; Lithium; Microscopy, Electron; N-Methylaspartate; Nerve Degeneration; Neurons; Neuroprotective Agents; Phosphopyruvate Hydratase; Rats; Treatment Outcome; Vacuoles; Valproic Acid | 2003 |
Sodium- and magnesium-valproate in vivo modulate glutamatergic and GABAergic synapses in the medial prefrontal cortex.
Topics: Action Potentials; Animals; Anticonvulsants; gamma-Aminobutyric Acid; Glutamic Acid; Kainic Acid; Magnesium; N-Methylaspartate; Prefrontal Cortex; Quisqualic Acid; Rats; Rats, Wistar; Salts; Sodium; Synapses; Valproic Acid | 2006 |
Chronic administration of valproic acid reduces brain NMDA signaling via arachidonic acid in unanesthetized rats.
Topics: Animals; Arachidonic Acid; Autoradiography; Behavior, Animal; Brain; Dinoprostone; Male; N-Methylaspartate; Rats; Rats, Inbred F344; Signal Transduction; Thromboxane B2; Valproic Acid | 2008 |
Vigabatrin but not valproate prevents development of age-specific flexion seizures induced by N-methyl-D-aspartate (NMDA) in immature rats.
Topics: Age Factors; Animals; Animals, Newborn; Anticonvulsants; Behavior, Animal; Disease Models, Animal; Epilepsy, Tonic-Clonic; Humans; Infant; N-Methylaspartate; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Seizures; Spasms, Infantile; Valproic Acid; Vigabatrin | 2010 |
Synaptic and intrinsic balancing during postnatal development in rat pups exposed to valproic acid in utero.
Topics: Abnormalities, Drug-Induced; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Female; Male; Models, Neurological; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Prefrontal Cortex; Pregnancy; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Synaptic Potentials; Time Factors; Valproic Acid | 2011 |
Valproic acid prevents NMDA-induced retinal ganglion cell death via stimulation of neuronal TrkB receptor signaling.
Topics: Animals; Cell Death; Mice; N-Methylaspartate; Neuroprotective Agents; Receptor, trkB; Retinal Ganglion Cells; Signal Transduction; Up-Regulation; Valproic Acid | 2015 |
Mechanism of microglia neuroprotection: Involvement of P2X7, TNFα, and valproic acid.
Topics: Adenosine Triphosphate; Animals; Cells, Cultured; Hippocampus; Mice, Inbred C57BL; Mice, Knockout; Microglia; N-Methylaspartate; Neurons; Neuroprotective Agents; Receptors, Purinergic P2X7; RNA, Messenger; Tissue Culture Techniques; Tumor Necrosis Factor-alpha; Up-Regulation; Valproic Acid | 2016 |
Regulation of P2X7 receptor function of neural progenitor cells in the hippocampal subgranular zone by neuronal activity in the dentate gyrus.
Topics: 4-Aminopyridine; Action Potentials; Adenosine Triphosphate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cells, Cultured; Dentate Gyrus; Female; Gabapentin; Male; Mice; Muscimol; N-Methylaspartate; Neural Stem Cells; Neurons; Phenytoin; Receptors, Purinergic P2X7; Tetrodotoxin; Valproic Acid | 2018 |
Valproic acid up-regulates the whole NO-citrulline cycle for potent iNOS-NO signaling to promote neuronal differentiation of adipose tissue-derived stem cells.
Topics: Adipose Tissue; Animals; Arginine; Argininosuccinate Synthase; Cell Differentiation; Citrulline; Enzyme Inhibitors; Male; N-Methylaspartate; Neurons; Nitric Oxide; Nitric Oxide Synthase Type II; Rats, Wistar; Signal Transduction; Stem Cells; Up-Regulation; Valproic Acid | 2021 |
Combined cell grafting and VPA administration facilitates neural repair through axonal regeneration and synaptogenesis in traumatic brain injury.
Topics: Animals; Axons; Brain Injuries, Traumatic; Mice; N-Methylaspartate; Neural Stem Cells; Neurons; Valproic Acid | 2022 |
Granulocyte Colony-Stimulating Factor Improved Core Symptoms of Autism Spectrum Disorder via Modulating Glutamatergic Receptors in the Prefrontal Cortex and Hippocampus of Rat Brains.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Autism Spectrum Disorder; Brain; Brain-Derived Neurotrophic Factor; Disease Models, Animal; Female; Granulocyte Colony-Stimulating Factor; Hippocampus; Humans; N-Methylaspartate; Neuroprotective Agents; Prefrontal Cortex; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Receptors, AMPA; Receptors, Glutamate; Risperidone; Saline Solution; Valproic Acid | 2022 |