n-methylaspartate has been researched along with valine in 212 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 117 (55.19) | 18.7374 |
| 1990's | 18 (8.49) | 18.2507 |
| 2000's | 46 (21.70) | 29.6817 |
| 2010's | 30 (14.15) | 24.3611 |
| 2020's | 1 (0.47) | 2.80 |
| Authors | Studies |
|---|---|
| Beckstead, RM; Somers, DL | 1 |
| Dreifuss, JJ; Raggenbass, M; Widmer, H | 1 |
| Arslan, M; Plant, TM; Pohl, CR; Smith, MS | 1 |
| Fukushima, R; Kizu, A; Miyagishi, T; Ono, T; Yoshida, Y | 1 |
| Clements, JD; Jahr, CE; Lester, RA; Westbrook, GL | 1 |
| Baron, BM; McDonald, IA; Miller, F; Muench, D; White, HS; Whitten, JP | 1 |
| Massey, SC; Miller, RF | 1 |
| Girault, JA; Greengard, P; Halpain, S | 1 |
| Gonzales, RA; Woodward, JJ | 1 |
| Biesterfeldt, JP; Compton, RP; Cordi, AA; Hood, WF; Lanthorn, TH; Monahan, JB; Vazquez, MI; Wood, PL | 1 |
| Akerman, KE; Holopainen, I | 1 |
| Aanonsen, LM; Wilcox, GL | 1 |
| Fischbach, GD; O'Brien, RJ | 1 |
| Cherubini, E; King, AE; Nistri, A | 1 |
| Moran, J; Patel, AJ | 1 |
| Buckley, KS; Collins, GG | 1 |
| Chambers, G; Cottrell, JE; Kass, IS | 1 |
| Haberly, LB; Hoffman, WH | 1 |
| Dudek, S; Joly, M; Lynch, G; Muller, D; Schottler, F; Thibault, O | 1 |
| Girdlestone, D; Thomson, AM; West, DC | 1 |
| Dingledine, R; Kleckner, NW; Verdoorn, TA | 1 |
| Chandler, SH | 1 |
| Greenberg, JH; Karp, A; Reivich, M; Uematsu, D | 1 |
| Hablitz, JJ; Sutor, B | 1 |
| Brugger, F; Olpe, HR; Pozza, MF; Steinmann, MW | 1 |
| Pierson, MG; Smith, KL; Swann, JW | 1 |
| Chapman, B; Miller, KD; Stryker, MP | 1 |
| Akoev, GN; Andrianov, IuN; Bromm, B; Sabo, T; Sherman, NO | 1 |
| Choi, DW; Hartley, DM | 1 |
| Dun, NJ; Minota, S; Miyazaki, T; Read, HL; Wang, MY | 1 |
| Anderson, WW; Clark, S; Stasheff, SF; Wilson, WA | 1 |
| Caspary, DM; Faingold, CL; Hoffmann, WE | 1 |
| Bowe, MA; Martin, D; Nadler, JV | 1 |
| Aizenman, E; Rosenberg, PA | 1 |
| Davidoff, RA; Hackman, JC; Zhang, DX | 1 |
| Miyachi, E; Murakami, M | 1 |
| Arslan, M; Plant, TM; Pohl, CR | 1 |
| Collins, JF; Klockgether, T; Schwarz, M; Sontag, KH; Turski, L; Turski, WA | 1 |
| Gibson, BL; Reif-Lehrer, L | 1 |
| Cunningham, JR; Neal, MJ | 1 |
| Lukasiewicz, PD; McReynolds, JS | 1 |
| Lodge, D; Martin, D | 2 |
| Hablitz, JJ | 1 |
| Martin, MR | 1 |
| Baudry, M; Cummins, JT; Kessler, M; Lynch, G; Way, S | 1 |
| Carpenter, DO; Ffrench-Mullen, JM; Hori, N | 1 |
| Curry, K; Magnuson, DS; McLennan, H; Peet, MJ | 1 |
| Canning, HM; Leach, MJ; Marden, CM | 1 |
| Collins, KJ; Wheatley, PL | 1 |
| Collins, JF; Stone, TW | 1 |
| Gregersen, H; McLennan, H; Peet, MJ | 1 |
| Frenk, H; Liban, A; Teichberg, VI; Urca, G | 1 |
| Koek, W; Ornstein, P; Woods, JH | 1 |
| Stone, TW | 1 |
| Davies, J; Evans, RH; Herrling, PL; Jones, AW; Olverman, HJ; Pook, P; Watkins, JC | 1 |
| Dragunow, M; Goddard, GV; Morimoto, K | 1 |
| De Belleroche, JS; Gardiner, IM; Hamilton, MH; Herberg, LJ | 1 |
| King, AE; Nistri, A | 1 |
| Costa, E; Nicoletti, F; Wroblewski, JT | 1 |
| Johnson, KM; Jones, SM; Snell, LD | 2 |
| Ballanyi, K; Endres, W; Grafe, P; Serve, G | 1 |
| Gordon, FJ | 1 |
| Fagg, GE; Foster, AC | 1 |
| Anderson, WW; Swartzwelder, HS; Wilson, WA | 1 |
| Gustafsson, B; Wigström, H | 1 |
| Ito, K; Izumi, Y; Kato, H; Kudo, Y; Miyakawa, H; Ogura, A | 1 |
| Avoli, M; Olivier, A | 1 |
| Cline, HT; Constantine-Paton, M; Debski, EA | 1 |
| Foster, AC; Wong, EH | 1 |
| Cherniack, NS; Mitra, J; Overholt, JL; Prabhakar, NR | 1 |
| Crepel, F; Dupont, JL; Gardette, R | 1 |
| Drejer, J; Honoré, T; Schousboe, A | 1 |
| Lees, GJ | 1 |
| Cherniack, NS; Deal, EC; Haxhiu, MA; Norcia, MP; Strohl, KP; van Lunteren, E | 1 |
| Crunelli, V; Kelly, JS; Leresche, N; Pirchio, M | 1 |
| de Carolis, AS; Frank, C; Sagratella, S | 1 |
| Bockaert, J; Kemp, DE; Schmidt, BH; Sebben, M; Sladeczek, F; Weiss, S | 1 |
| Raigorodsky, G; Urca, G | 2 |
| Barry, MJ; O'Donovan, MJ | 1 |
| Choi, DW; Koh, JY; Peters, S | 1 |
| Aram, JA; Lodge, D | 1 |
| Childs, AM; Evans, RH; Watkins, JC | 1 |
| Caudle, RM; Isaac, L | 2 |
| Burton, NR; Smith, DA; Stone, TW | 1 |
| Beart, PM; Headley, PM; Nicolopoulos, LS; West, DC | 1 |
| Choi, DW; Coulter, DA; Prince, DA; Wong, BY | 1 |
| Ambar, I; Kloog, Y; Sokolovsky, M | 1 |
| Bockaert, J; Pin, JP; Van-Vliet, BJ | 1 |
| Connick, JH; Stone, TW | 1 |
| Carter, CJ; L'Heureux, R; Scatton, B | 1 |
| Pastuszko, A; Wilson, DF | 1 |
| Nishizaki, T; Okada, Y | 1 |
| Lopes da Silva, FH; Melchers, BP; Pennartz, CM; Wadman, WJ | 1 |
| Lee, M; Strahlendorf, HK; Strahlendorf, JC | 1 |
| Fletcher, EJ; Lodge, D | 1 |
| Dingledine, R; Verdoorn, TA | 1 |
| King, AE; Thompson, SW; Urban, L; Woolf, CJ | 1 |
| Astier, H; Tapia-Arancibia, L | 1 |
| Mayer, ML; Vyklický, L; Westbrook, GL | 1 |
| Ben-Ari, Y; Cherubini, E; Neuman, R | 1 |
| Beitz, AJ; Larson, AA | 1 |
| Lynch, G; Muller, D | 1 |
| Burton, NR; Smith, DA; Stone, TW; Williams, TL | 2 |
| Coleman, PA; Miller, RF | 1 |
| Beart, PM; Davies, SN; Jones, MG; Lodge, D; Manallack, DT; Millar, J; Ornstein, PL; Verberne, AJ; Young, N | 1 |
| Linden, DJ; Routtenberg, A; Sheu, FS; Wong, KL | 1 |
| Lauritzen, M; Nicholson, C; Okada, Y; Rice, ME | 1 |
| Balázs, R; Hack, N; Jørgensen, OS | 1 |
| Baudry, M; Jung, MW; Larson, J; Lynch, G; Oliver, M; Seubert, P | 1 |
| Ben-Ari, Y; Corradetti, R; Gaïarsa, JL | 1 |
| Armstrong-James, M; Fox, K | 1 |
| Collins, JF; Curry, K; Perkins, MN; Stone, TW | 1 |
| Collins, JF; Curry, K; Labruyere, J; Olney, JW | 1 |
| Collins, GG | 1 |
| Close, JM; Loewy, AD; Neil, JJ | 1 |
| Lehmann, J; Scatton, B | 1 |
| Eng, P; Hösli, E; Hösli, L; Lehmann, R | 1 |
| Collingridge, GL; Kehl, SJ; McLennan, H | 1 |
| Crunelli, V; Forda, S; Kelly, JS | 1 |
| Collins, JF; Croucher, MJ; Curry, K; Czuczwar, SJ; Joseph, M; Meldrum, BS; Stone, TW | 1 |
| Joëls, M; Urban, IJ | 1 |
| McLennan, H | 1 |
| Mayer, ML; Westbrook, GL | 1 |
| Becquet, D; Deprez, P; Fache, MP; Faudon, M; Giraud, P; Héry, F; Héry, M | 1 |
| Baron, BM; Fisher, M; Hasegawa, Y; Metcalf, G | 1 |
| Xue, GP; Zhang, DS; Zhang, L; Zhang, SS | 1 |
| Berrino, L; D'Amico, M; de Novellis, V; Pizzirusso, A; Rossi, F | 1 |
| Hu, PS; Ross, SB | 1 |
| Gatherer, M; Sundstrom, LE | 1 |
| Mele, A; Oliverio, A; Roullet, P; Sargolini, F | 1 |
| Empson, RM; Gee, VJ; Newberry, NR; Sheardown, MJ | 1 |
| Gorji, A; Köhling, R; Scheller, D; Speckmann, EJ; Straub, H; Tegtmeier, F | 1 |
| Aihara, H; Kondoh, T; Nishizaki, T; Tamaki, N | 1 |
| Guo, Y; Sánchez, C; Udin, SB | 1 |
| Lei, S; McBain, CJ | 1 |
| Hayashi, H; Hirotsu, K; Kagamiyama, H; Miyahara, I; Mizuguchi, H; Nakajima, Y | 1 |
| Iino, M; Kakegawa, W; Ozawa, S; Tsuzuki, K | 1 |
| Amamoto, T; Ando, S; Fujiwara, M; Nakanishi, H; Okada, M; Urae, R; Yazawa, K | 1 |
| Gao, CQ; Kaufman, JM | 1 |
| Chen, A; Hough, CJ; Li, H | 1 |
| Albers, HE; Fukuhara, C; Paul, KN; Tosini, G | 1 |
| Fleischer, W; Görtz, P; Hoinkes, A; Otto, F; Schwahn, B; Siebler, M; Wendel, U | 1 |
| Häusser, M; Nelson, SB; Sjöström, PJ; Turrigiano, GG; Watt, AJ | 1 |
| Aizenman, E; Hara, H | 1 |
| Lin, TB | 1 |
| Lee, YJ; Tsai, LH; Wu, JY | 1 |
| Futai, K; Hayashi, Y; Lashuel, HA; Lo, I; Nakagawa, T; Okamoto, K; Sheng, M; Walz, T | 1 |
| Grantyn, R; Henneberger, C; Jüttner, R; Meier, JC; Rothe, T; Schmidt, SA; Walter, J | 1 |
| Breitinger, HG; Frermann, D; Hollmann, M; Keller, BU; Paarmann, I; Villmann, C | 1 |
| Knöpfel, T; Mutoh, H; Yuan, Q | 1 |
| Hori, K; Kobayashi, M; Masaki, T; Masuo, Y; Miyamoto, M; Noguchi, H; Nomura, M; Takamatsu, K; Tsubokawa, H | 1 |
| Anderson, AJ; Garraway, SM; Mendell, LM | 1 |
| Ellis-Davies, GC; Kasai, H; Matsuzaki, M; Noguchi, J | 1 |
| Auberson, YP; Baumgart, JP; Kim, MJ; McCormack, SG; Osten, P; Pak, D; Qin, Y; Sheng, M; van Aelst, L; Velamoor, V; Zhu, JJ; Zhu, Y | 1 |
| Boeck, CR; Bronzatto, MJ; Jardim, FM; Kroth, EH; Souza, DO; Vendite, D | 1 |
| Hvalby, Ø; Jensen, V; Köhr, G; Kvello, A; Pawlak, V; Schupp, BJ; Seeburg, PH | 1 |
| Gao, E; Ji, W; Suga, N | 1 |
| Grillner, S; Hill, RH; Tsvyetlynska, NA | 1 |
| Darbon, P; Legrand, JC; Streit, J | 1 |
| Laute, MA; Manto, M; Pandolfo, M | 1 |
| Alavez, S; Blancas, S; Morán, J | 1 |
| Addae, JI; Stone, TW; Youssef, FF | 1 |
| Dell'Acqua, ML; Gibson, ES; Smith, KE | 1 |
| Baudry, M; Zhou, M | 1 |
| Yonehara, N; Yoshimura, M | 1 |
| Carpenter-Hyland, EP; Chandler, LJ | 1 |
| Bargas, J; Galarraga, E; Guzman, JN; Lopez-Huerta, VG; Tecuapetla, F | 1 |
| Hsu, KS; Huang, CC | 1 |
| Gonzalo-Gobernado, R; Gonźlez-Vigueras, JM; Herranz, AS; Rodríguez-Navarro, JA; Solís, JM | 1 |
| Farb, DH; Gibbs, TT; Whittaker, MT | 1 |
| Bennett, MV; Rodenas-Ruano, A; Takayasu, Y; Takeuchi, K; Yang, Y; Zukin, RS | 1 |
| Dringenberg, HC; Habib, D | 1 |
| Cohen, D; Segal, M | 1 |
| Fisher, G; Galindo, E; Szókán, G; Tsesarskaia, M | 1 |
| Blankenship, AG; Copenhagen, DR; Edwards, RH; Feller, MB; Ford, KJ; Johnson, J; Seal, RP | 1 |
| Chen, BS; Roche, KW | 1 |
| Berry, JN; Butler, TR; Littleton, JM; Mulholland, PJ; Pauly, JR; Prendergast, MA; Self, RL; Sharrett-Field, LJ; Smith, KJ | 1 |
| Abbas, AK; Afanasenkau, D; Huang, FS; Li, R; Wigström, H | 1 |
| Baba, H; Furue, H; Georgiev, SK; Kohno, T | 1 |
| Dergacheva, O; Jameson, H; Lovett-Barr, MR; Mendelowitz, D; Wang, X | 1 |
| Gire, DH; Pandipati, S; Schoppa, NE | 1 |
| Jiao, YY; Sun, QQ; Zhang, Z | 1 |
| Hall, BJ; Patrick, GN; Schwarz, LA | 1 |
| Colledge, WH; d'Anglemont de Tassigny, X; Herbison, AE; Liu, X; Millar, R; Petersen, SL; Porteous, R | 1 |
| Moenter, SM; Roland, AV | 1 |
| Deng, Q; Fellin, T; Haydon, PG; Moss, SJ; Terunuma, M | 1 |
| Bai, Y; Chen, L; Li, L; Qi, J; Qi, Z; Sun, K; Yang, R; Zhang, Z; Zhou, L | 1 |
| Chen, JP; Hsu, KS; Huang, CC; Yeh, CM | 1 |
| Ardiles, A; Guo, Y; He, K; Huang, S; Huganir, R; Kirkwood, A; Palacios, A; Pasquale, Rd; Treviño, M | 1 |
| Mikroulis, AV; Psarropoulou, C | 1 |
| Bach, EC; Smith, BN | 1 |
| Ahmad, F; Blaesse, P; Kaila, K; Puskarjov, M | 1 |
| Casanova, JE; Conger, KK; Myers, KR; Sheng, Y; Wang, G; Zhu, JJ | 1 |
| Crawford, DC; Jiang, X; Mennerick, S; Taylor, A | 1 |
| Chang, JC; Chang, WP; Chen, IM; Cheng, JK; Chiu, HF; Lin, CH; Lin, CI; Lin, PH | 1 |
| Borszcz, GS; Spuz, CA; Tomaszycki, ML | 1 |
| Landeira-Fernandez, J | 1 |
| Hernan, AE; Pehek, EA | 1 |
| Fujii, S; Yamazaki, Y | 1 |
| Galvin, C; Lee, FS; Ninan, I | 1 |
| Connors, BW; Crandall, SR; Cruikshank, SJ | 1 |
| Addy, NA; Nunes, EJ; Solecki, WB; Wickham, RJ | 1 |
| Nazarinia, E; Rezayof, A; Sardari, M; Yazdanbakhsh, N | 1 |
| Barberis, A; Cella Zanacchi, F; Das, S; Del Bue, A; Diaspro, A; Nieus, T; Pennacchietti, F; Petrini, EM; Rosillo, C; Tyagarajan, SK; Vascon, S | 1 |
| Ashkenazi, S; Berent, E; Weizman, A; Yuhas, Y | 1 |
| Copeland, CS; Neale, SA; Nisenbaum, E; Parri, HR; Salt, TE; Sims, RE; Wall, TM | 1 |
| Bing, YH; Chu, CP; Cui, BR; Cui, LN; Li, BX; Qiu, DL; Zhang, GJ; Zhang, XY | 1 |
1 review(s) available for n-methylaspartate and valine
| Article | Year |
|---|---|
On the excitatory post-synaptic potential evoked by stimulation of the optic tract in the rat lateral geniculate nucleus.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Aminobutyrates; Animals; Aspartic Acid; Calcium; Dipeptides; Glutamates; Glutamic Acid; In Vitro Techniques; Male; N-Methylaspartate; Neurons; Optic Nerve; Rats; Rats, Inbred Strains; Synapses; Thalamic Nuclei; Valine | 1987 |
211 other study(ies) available for n-methylaspartate and valine
| Article | Year |
|---|---|
N-methyl-D-aspartate receptor antagonism alters substance P and met5-enkephalin biosynthesis in neurons of the rat striatum.
Topics: Animals; Corpus Striatum; Enkephalin, Methionine; Enkephalins; Male; N-Methylaspartate; Neurons; Piperazines; Protein Precursors; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Substance P; Tachykinins; Valine | 1992 |
N-methyl-D-aspartate and vasopressin activate distinct voltage-dependent inward currents in facial motoneurones.
Topics: Animals; Arginine Vasopressin; Brain Stem; Dizocilpine Maleate; Electric Conductivity; Evoked Potentials; Facial Nerve; In Vitro Techniques; Membrane Potentials; Motor Neurons; N-Methylaspartate; Rats; Rats, Sprague-Dawley; Valine | 1992 |
Studies of the role of the N-methyl-D-aspartate (NMDA) receptor in the hypothalamic control of prolactin secretion.
Topics: Animals; Hypothalamus; Male; N-Methylaspartate; Prolactin; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Valine | 1992 |
Striatal N-methyl-D-aspartate receptors in haloperidol-induced catalepsy.
Topics: Animals; Catalepsy; Cerebral Cortex; Corpus Striatum; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; Haloperidol; Male; N-Methylaspartate; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Valine | 1991 |
Channel kinetics determine the time course of NMDA receptor-mediated synaptic currents.
Topics: Animals; Animals, Newborn; Aspartic Acid; Cells, Cultured; Evoked Potentials; Glutamates; Glutamic Acid; Hippocampus; Kinetics; N-Methylaspartate; Neurons; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Synapses; Valine | 1990 |
(R)-4-oxo-5-phosphononorvaline: a new competitive glutamate antagonist at the NMDA receptor complex.
Topics: Animals; Binding, Competitive; Cerebellum; Cyclic GMP; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; Kindling, Neurologic; Mice; Mice, Inbred DBA; N-Methylaspartate; Rats; Receptors, N-Methyl-D-Aspartate; Valine | 1990 |
N-methyl-D-aspartate receptors of ganglion cells in rabbit retina.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Electrophysiology; In Vitro Techniques; N-Methylaspartate; Rabbits; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Retina; Retinal Ganglion Cells; Valine | 1990 |
Activation of NMDA receptors induces dephosphorylation of DARPP-32 in rat striatal slices.
Topics: Animals; Aspartic Acid; Calcineurin; Calmodulin-Binding Proteins; Colforsin; Corpus Striatum; Cyclic AMP; Dibenzocycloheptenes; Dizocilpine Maleate; Dopamine and cAMP-Regulated Phosphoprotein 32; Enzyme Activation; N-Methylaspartate; Nerve Tissue Proteins; Phosphates; Phosphoprotein Phosphatases; Phosphoproteins; Phosphorylation; Phosphothreonine; Protein Kinases; Protein Phosphatase 1; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine | 1990 |
Ethanol inhibits N-methyl-D-aspartate-stimulated [3H]norepinephrine release from rat cortical slices.
Topics: Animals; Aspartic Acid; Cerebral Cortex; Culture Techniques; Ethanol; Glycine; Magnesium; Male; N-Methylaspartate; Norepinephrine; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Tetrodotoxin; Valine | 1990 |
Differential modulation of the associated glycine recognition site by competitive N-methyl-D-aspartate receptor antagonists.
Topics: Amino Acids; Animals; Aspartic Acid; Binding Sites; Binding, Competitive; Glycine; Male; N-Methylaspartate; Organophosphorus Compounds; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine | 1990 |
Efflux of 45calcium from cultured primary astrocytes: effects of glutamate receptor agonists and antagonists.
Topics: Animals; Animals, Newborn; Astrocytes; Calcium; Calcium Radioisotopes; Cells, Cultured; Excitatory Amino Acid Antagonists; Glutamates; Kainic Acid; N-Methylaspartate; Quisqualic Acid; Rats; Receptors, Glutamate; Receptors, Neurotransmitter; Valine | 1990 |
Phencyclidine selectively blocks a spinal action of N-methyl-D-aspartate in mice.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Dipeptides; Drug Interactions; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Glutamates; Glutamic Acid; Injections, Spinal; Kainic Acid; Male; Mice; N-Methylaspartate; Norepinephrine; Oxadiazoles; Phencyclidine; Quisqualic Acid; Spinal Cord; Substance P; Tetrazoles; Valine | 1986 |
Characterization of excitatory amino acid receptors expressed by embryonic chick motoneurons in vitro.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Cells, Cultured; Chick Embryo; Dose-Response Relationship, Drug; Electrophysiology; Excitatory Amino Acid Antagonists; Glutamates; In Vitro Techniques; Ion Channels; Kainic Acid; Membrane Potentials; Motor Neurons; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Receptors, Glutamate; Receptors, Neurotransmitter; Spinal Cord; Valine | 1986 |
A study of amino acid-activated currents recorded from frog motoneurones in vitro.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anterior Horn Cells; Aspartic Acid; Glutamates; Glutamic Acid; In Vitro Techniques; Ion Channels; Membrane Potentials; Motor Neurons; N-Methylaspartate; Neural Conduction; Oxadiazoles; Quisqualic Acid; Rana temporaria; Valine | 1987 |
Stimulation of the N-methyl-D-aspartate receptor promotes the biochemical differentiation of cerebellar granule neurons and not astrocytes.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Astrocytes; Cell Differentiation; Cells, Cultured; Cerebellum; Glutaminase; N-Methylaspartate; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; RNA; Valine | 1989 |
Antagonism of monosynaptic excitations in the mouse olfactory cortex slice by 6,7-dinitroquinoxaline-2,3-dione.
Topics: Animals; Aspartic Acid; Cerebral Cortex; In Vitro Techniques; Male; Mice; N-Methylaspartate; Oxadiazoles; Pyramidal Tracts; Quinoxalines; Quisqualic Acid; Receptors, AMPA; Receptors, Kainic Acid; Receptors, Neurotransmitter; Reflex, Monosynaptic; Synapses; Synaptic Transmission; Valine | 1989 |
The N-methyl-D-aspartate antagonists aminophosphonovaleric acid and MK-801 reduce anoxic damage to dentate granule and CA1 pyramidal cells in the rat hippocampal slice.
Topics: 2-Amino-5-phosphonovalerate; Adenosine Triphosphate; Animals; Anticonvulsants; Aspartic Acid; Dibenzocycloheptenes; Dizocilpine Maleate; Evoked Potentials; Hippocampus; Hypoxia; In Vitro Techniques; Male; N-Methylaspartate; Neurotoxins; Pyramidal Tracts; Rats; Rats, Inbred Strains; Valine | 1989 |
Bursting induces persistent all-or-none EPSPs by an NMDA-dependent process in piriform cortex.
Topics: 2-Amino-5-phosphonovalerate; 4-Aminopyridine; Aminopyridines; Animals; Aspartic Acid; Cerebral Cortex; Chlorides; In Vitro Techniques; Ketamine; Magnesium; Membrane Potentials; N-Methylaspartate; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Synapses; Time Factors; Valine | 1989 |
Long-lasting physiological effects of bath applied N-methyl-D-aspartate.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Electric Stimulation; Glycine; Hippocampus; In Vitro Techniques; Male; N-Methylaspartate; Rats; Rats, Inbred Strains; Spermine; Time Factors; Valine | 1989 |
A local circuit neocortical synapse that operates via both NMDA and non-NMDA receptors.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anticonvulsants; Aspartic Acid; Cerebral Cortex; Dipeptides; Electric Stimulation; Female; Ibotenic Acid; In Vitro Techniques; N-Methylaspartate; Neural Conduction; Oxazoles; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Synapses; Valine | 1989 |
N-methyl-D-aspartate/glycine and quisqualate/kainate receptors expressed in Xenopus oocytes: antagonist pharmacology.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Aspartic Acid; Kainic Acid; N-Methylaspartate; Oocytes; Quinoxalines; Receptors, AMPA; Receptors, Glycine; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine | 1989 |
Evidence for excitatory amino acid transmission between mesencephalic nucleus of V afferents and jaw-closer motoneurons in the guinea pig.
Topics: 2-Amino-5-phosphonovalerate; Afferent Pathways; Amino Acids; Aminobutyrates; Animals; Aspartic Acid; Dipeptides; Evoked Potentials; Guinea Pigs; Kynurenic Acid; Male; Masseter Muscle; Mesencephalon; Motor Neurons; N-Methylaspartate; Neurotransmitter Agents; Synapses; Synaptic Transmission; Trigeminal Nuclei; Valine | 1989 |
Cytosolic free calcium and NAD/NADH redox state in the cat cortex during in vivo activation of NMDA receptors.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Calcium; Cats; Cerebral Cortex; Cytosol; Fluorescent Dyes; In Vitro Techniques; Male; N-Methylaspartate; NAD; Oxidation-Reduction; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine | 1989 |
EPSPs in rat neocortical neurons in vitro. II. Involvement of N-methyl-D-aspartate receptors in the generation of EPSPs.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Cerebral Cortex; Evoked Potentials; In Vitro Techniques; Magnesium; Male; N-Methylaspartate; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine | 1989 |
Excitatory amino acid receptors in rat locus coeruleus. An extracellular in vitro study.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Aspartic Acid; Glutamates; In Vitro Techniques; Kainic Acid; Locus Coeruleus; Magnesium; Male; N-Methylaspartate; Neurons; Oxadiazoles; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, Cell Surface; Valine | 1989 |
A slow NMDA-mediated synaptic potential underlies seizures originating from midbrain.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Bicuculline; In Vitro Techniques; Inferior Colliculi; N-Methylaspartate; Picrotoxin; Rats; Seizures; Valine | 1989 |
Visual responses in adult cat visual cortex depend on N-methyl-D-aspartate receptors.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Aspartic Acid; Cats; Electric Conductivity; Kainic Acid; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine; Visual Cortex; Visual Perception | 1989 |
[Analysis of the effect of quisqualate, N-methyl-D- aspartate and several blockers of amino acid receptors on synaptic transmission in the ampullae of Lorenzini].
Topics: 2-Amino-5-phosphonovalerate; 2-Aminoadipic Acid; Aminobutyrates; Animals; Aspartic Acid; Electric Fish; Evoked Potentials; Magnesium; Membrane Potentials; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Sensory Receptor Cells; Skates, Fish; Synapses; Synaptic Transmission; Valine | 1989 |
Delayed rescue of N-methyl-D-aspartate receptor-mediated neuronal injury in cortical culture.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Aspartic Acid; Calcium; Cells, Cultured; Cerebral Cortex; Glutamates; Glutamic Acid; Mice; N-Methylaspartate; Neurons; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Sodium; Valine | 1989 |
Glycine potentiates NMDA responses in rat hippocampal CA1 neurons.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Animals; Aspartic Acid; Glycine; Hippocampus; Humans; N-Methylaspartate; Rats; Valine | 1989 |
NMDA antagonists differentiate epileptogenesis from seizure expression in an in vitro model.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Aspartic Acid; Dibenzocycloheptenes; Disease Models, Animal; Dizocilpine Maleate; Electric Stimulation; Electrophysiology; Epilepsy; Evoked Potentials; Hippocampus; In Vitro Techniques; N-Methylaspartate; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Seizures; Valine | 1989 |
Effects of excitant amino acids on acoustic responses of inferior colliculus neurons.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Animals; Aspartic Acid; Glutamates; Glutamic Acid; Inferior Colliculi; N-Methylaspartate; Parasympathomimetics; Rats; Rats, Inbred Strains; Valine | 1989 |
A grease-gap method for studying the excitatory amino acid pharmacology of CA1 hippocampal pyramidal cells.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Anticonvulsants; Aspartic Acid; Electrophysiology; Female; Glutamates; Hippocampus; Ibotenic Acid; Kainic Acid; Magnesium; N-Methylaspartate; Neurons; Phencyclidine; Rats; Rats, Inbred Strains; Valine | 1989 |
Hundred-fold increase in neuronal vulnerability to glutamate toxicity in astrocyte-poor cultures of rat cerebral cortex.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Astrocytes; Cells, Cultured; Cerebral Cortex; Chromatography, High Pressure Liquid; Electrophysiology; Glutamates; Glycine; Hippocampus; Histocytochemistry; N-Methylaspartate; Neurons; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine | 1989 |
NMDA antagonists and potentiation of NMDA-induced motoneuron depolarizations in the isolated frog spinal cord.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Cell Membrane; Dibenzocycloheptenes; Dizocilpine Maleate; Drug Synergism; Evoked Potentials; Ketamine; Kynurenic Acid; Magnesium; Motor Neurons; N-Methylaspartate; Potassium; Rana pipiens; Spinal Cord; Valine | 1989 |
Coexistence of NMDA and non-NMDA receptors on turtle horizontal cells revealed using isolated retina preparations.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Evoked Potentials, Visual; In Vitro Techniques; Kainic Acid; N-Methylaspartate; Neuromuscular Depolarizing Agents; Oxadiazoles; Quisqualic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Retina; Turtles; Valine | 1989 |
DL-2-amino-5-phosphonopentanoic acid, a specific N-methyl-D-aspartic acid receptor antagonist, suppresses pulsatile LH release in the rat.
Topics: Animals; Aspartic Acid; Luteinizing Hormone; Male; N-Methylaspartate; Orchiectomy; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine | 1988 |
Muscle relaxant action of excitatory amino acid antagonists.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Female; Glutamates; Kynurenic Acid; Male; Muscle Relaxants, Central; Muscle Spasticity; N-Methylaspartate; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine | 1985 |
Mg2+ reduces N-methyl-D-aspartate neurotoxicity in embryonic chick neural retina in vitro.
Topics: 2-Amino-5-phosphonovalerate; 2-Aminoadipic Acid; Animals; Aspartic Acid; Chick Embryo; In Vitro Techniques; Magnesium; N-Methylaspartate; Retina; Valine | 1985 |
Effect of excitatory amino acids and analogues on [3H]acetylcholine release from amacrine cells of the rabbit retina.
Topics: 2-Amino-5-phosphonovalerate; Acetylcholine; Amino Acids; Aminobutyrates; Animals; Aspartic Acid; Cholinergic Fibers; Electroretinography; N-Methylaspartate; Neurons; Pipecolic Acids; Rabbits; Receptors, Amino Acid; Receptors, Cell Surface; Retina; Valine | 1985 |
Synaptic transmission at N-methyl-D-aspartate receptors in the proximal retina of the mudpuppy.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Amino Acids; Animals; Aspartic Acid; In Vitro Techniques; N-Methylaspartate; Necturus; Receptors, Amino Acid; Receptors, Cell Surface; Retina; Retinal Ganglion Cells; Synapses; Synaptic Transmission; Valine | 1985 |
Ketamine acts as a non-competitive N-methyl-D-aspartate antagonist on frog spinal cord in vitro.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Kainic Acid; Ketamine; Magnesium; Motor Neurons; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Rana pipiens; Rana temporaria; Spinal Cord; Valine | 1985 |
Action of excitatory amino acids and their antagonists on hippocampal neurons.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Amino Acids; Aminobutyrates; Animals; Aspartic Acid; Excitatory Amino Acid Antagonists; Glutamic Acid; Guinea Pigs; Hippocampus; Iontophoresis; Manganese; N-Methylaspartate; Neurons; Oxadiazoles; Quisqualic Acid; Tetrodotoxin; Valine | 1985 |
Evidence for an excitatory amino acid as the transmitter of the auditory nerve in the in vitro mouse cochlear nucleus.
Topics: 2-Amino-5-phosphonovalerate; 2-Aminoadipic Acid; Action Potentials; Amino Acids; Animals; Aspartic Acid; Cochlear Nerve; Dose-Response Relationship, Drug; Evoked Potentials; Female; Kainic Acid; Male; Mice; Mice, Inbred C3H; N-Methylaspartate; Neurotransmitter Agents; Oxadiazoles; Pipecolic Acids; Quisqualic Acid; Receptors, Neurotransmitter; Valine; Vestibulocochlear Nerve | 1985 |
Induction of glutamate binding sites in hippocampal membranes by transient exposure to high concentrations of glutamate or glutamate analogs.
Topics: 2-Amino-5-phosphonovalerate; 2-Aminoadipic Acid; Aminobutyrates; Animals; Aspartic Acid; Binding Sites; Chlorides; Chromatography, High Pressure Liquid; Glutamates; Glutamic Acid; Hippocampus; Homocysteine; Kainic Acid; Kinetics; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Rats; Receptors, Glutamate; Receptors, Neurotransmitter; Saponins; Sodium; Valine | 1986 |
A comparison of the effects of quinolinate and N-methyl-aspartate on neurons in rat piriform cortex.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Amino Acids; Animals; Aspartic Acid; Cerebral Cortex; Dose-Response Relationship, Drug; Electric Stimulation; Iontophoresis; N-Methylaspartate; Neurons; Pyridines; Quinolinic Acids; Rats; Valine | 1986 |
Ca2+-dependent depolarization and burst firing of rat CA1 pyramidal neurones induced by N-methyl-D-aspartic acid and quinolinic acid: antagonism by 2-amino-5-phosphonovaleric and kynurenic acids.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Aspartic Acid; Calcium; Convulsants; Electric Conductivity; Electric Stimulation; Evoked Potentials; Hippocampus; In Vitro Techniques; Kynurenic Acid; N-Methylaspartate; Neurons; Oxadiazoles; Pyramidal Tracts; Pyridines; Quinolinic Acid; Quinolinic Acids; Quisqualic Acid; Rats; Valine | 1986 |
(+/-)-cis-2,3-Piperidine dicarboxylic acid is a partial N-methyl-D-aspartate agonist in the in vitro rat cerebellar cGMP model.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Aspartic Acid; Cerebellum; Cyclic GMP; Dose-Response Relationship, Drug; Female; In Vitro Techniques; Magnesium; Male; N-Methylaspartate; Pipecolic Acids; Rats; Rats, Inbred Strains; Valine | 1986 |
Quantitative studies of N-methyl-D-aspartate, 2-amino-5-phosphonovalerate and cis-2,3-piperidine dicarboxylate interactions on the neonatal rat spinal cord in vitro.
Topics: 2-Amino-5-phosphonovalerate; Animals; Animals, Newborn; Aspartic Acid; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Electrophysiology; In Vitro Techniques; Membrane Potentials; N-Methylaspartate; Pipecolic Acids; Rats; Rats, Inbred Strains; Spinal Cord; Valine | 1986 |
Activity of beta-kainic acid on neocortical neurons in vivo and hippocampal neurons in vitro.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Cerebral Cortex; Dipeptides; Dose-Response Relationship, Drug; Evoked Potentials, Somatosensory; Hippocampus; Iontophoresis; Kainic Acid; Male; N-Methylaspartate; Neurons; Rats; Receptors, Neurotransmitter; Valine | 1986 |
2-Amino-5-phosphonovalerate and Co2+ selectively block depolarization and burst firing of rat hippocampal CA1 pyramidal neurones by N-methyl-D-aspartate.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Animals; Aspartic Acid; Cobalt; Evoked Potentials; Hippocampus; Iontophoresis; N-Methylaspartate; Neurons; Oxadiazoles; Pyramidal Tracts; Quisqualic Acid; Rats; Tetrodotoxin; Valine | 1986 |
Absence of side-effects in the anticonvulsant action of cortically applied antagonists of N-methyl-D-aspartate.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Aspartic Acid; Dipeptides; Morphine; N-Methylaspartate; Picrotoxin; Quinoxalines; Rats; Rats, Inbred Strains; Seizures; Strychnine; Valine | 1986 |
Phencyclidine-like behavioral effects in pigeons induced by systemic administration of the excitatory amino acid antagonist, 2-amino-5-phosphonovalerate.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Behavior, Animal; Catalepsy; Columbidae; Dose-Response Relationship, Drug; Injections, Intraventricular; N-Methylaspartate; Phencyclidine; Stereotyped Behavior; Valine | 1986 |
The relative potencies of (-)-2-amino-5-phosphonovalerate and (-)-2-amino-7-phosphonoheptanoate as antagonists of N-methylaspartate and quinolinic acids and repetitive spikes in rat hippocampal slices.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Amino Acids; Animals; Aspartic Acid; Evoked Potentials; Hippocampus; In Vitro Techniques; Male; N-Methylaspartate; Pyridines; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains; Valine | 1986 |
CPP, a new potent and selective NMDA antagonist. Depression of central neuron responses, affinity for [3H]D-AP5 binding sites on brain membranes and anticonvulsant activity.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Aspartic Acid; Binding Sites; Brain; Cats; Cell Membrane; Interneurons; Membrane Potentials; Mice; Motor Neurons; N-Methylaspartate; Neurons; Piperazines; Rats; Spinal Cord; Valine | 1986 |
Deep prepyriform cortex kindling and its relation to amygdala kindling in the rat.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Amygdala; Animals; Aspartic Acid; Cerebral Cortex; Electroencephalography; gamma-Aminobutyric Acid; Kindling, Neurologic; Male; Muscimol; N-Methylaspartate; Rats; Valine | 1986 |
Stimulatory effect of N-methyl aspartate on locomotor activity and transmitter release from rat nucleus accumbens.
Topics: 2-Amino-5-phosphonovalerate; Acetylcholine; Animals; Aspartic Acid; Corpus Striatum; Dopamine; In Vitro Techniques; Male; Motor Activity; N-Methylaspartate; Nialamide; Nucleus Accumbens; Rats; Rats, Inbred Strains; Septal Nuclei; Valine | 1986 |
Blockade by D-aminophosphonovalerate or Mg2+ of excitatory amino acid-induced responses on spinal motoneurons in vitro.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Electric Conductivity; Excitatory Amino Acid Antagonists; In Vitro Techniques; Magnesium; Membrane Potentials; Motor Neurons; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Rana temporaria; Synaptic Transmission; Valine | 1986 |
Magnesium ions inhibit the stimulation of inositol phospholipid hydrolysis by endogenous excitatory amino acids in primary cultures of cerebellar granule cells.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Cells, Cultured; Cerebellum; Drug Synergism; Glutamates; Glutamic Acid; Hydrolysis; Inositol Phosphates; Kainic Acid; Magnesium; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Rats; Sugar Phosphates; Valine; Veratridine | 1987 |
Phencyclidine selectively inhibits N-methyl-D-aspartate-induced hippocampal [3H]norepinephrine release.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Hippocampus; In Vitro Techniques; Kainic Acid; Magnesium; Male; N-Methylaspartate; Norepinephrine; Phencyclidine; Rats; Structure-Activity Relationship; Valine | 1987 |
Excitatory amino acids and intracellular pH in motoneurons of the isolated frog spinal cord.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anterior Horn Cells; Anura; Aspartic Acid; Hydrogen-Ion Concentration; In Vitro Techniques; Kainic Acid; Motor Neurons; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Valine | 1986 |
Aortic baroreceptor reflexes are mediated by NMDA receptors in caudal ventrolateral medulla.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aorta; Aspartic Acid; Electric Stimulation; Female; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Injections, Intraventricular; Medulla Oblongata; Microinjections; N-Methylaspartate; Pressoreceptors; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Reflex; Synaptic Transmission; Valine | 1987 |
Comparison of L-[3H]glutamate, D-[3H]aspartate, DL-[3H]AP5 and [3H]NMDA as ligands for NMDA receptors in crude postsynaptic densities from rat brain.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Binding, Competitive; Brain; Brain Chemistry; Chemical Phenomena; Chemistry; Glutamates; Glutamic Acid; Male; N-Methylaspartate; Radioligand Assay; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine | 1987 |
The NMDA receptor antagonist 2-amino-5-phosphonovalerate blocks stimulus train-induced epileptogenesis but not epileptiform bursting in the rat hippocampal slice.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Electric Stimulation; Electrophysiology; Epilepsy; Hippocampus; Male; N-Methylaspartate; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine | 1987 |
Postsynaptic control of hippocampal long-term potentiation.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Aspartic Acid; Evoked Potentials; GABA Antagonists; Guinea Pigs; Hippocampus; In Vitro Techniques; N-Methylaspartate; Picrotoxin; Synapses; Valine | 1986 |
Biphasic effect of quinolinate on frog spinal, but not rat cortical, neurones: N-methyl-D-aspartate-like depolarisation and a novel type of hyperpolarisation.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anterior Horn Cells; Anura; Aspartic Acid; Drug Interactions; Gyrus Cinguli; Kainic Acid; Ketamine; Magnesium; Membrane Potentials; Motor Neurons; N-Methylaspartate; Pyridines; Quinolinic Acid; Quinolinic Acids; Rats; Valine | 1987 |
Cytoplasmic calcium elevation in hippocampal granule cell induced by perforant path stimulation and L-glutamate application.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Animals; Anticonvulsants; Aspartic Acid; Benzofurans; Calcium; Cytoplasm; Egtazic Acid; Electric Stimulation; Fluorescent Dyes; Fura-2; Glutamates; Glutamic Acid; Guinea Pigs; Hippocampus; In Vitro Techniques; N-Methylaspartate; Neural Pathways; Tetrodotoxin; Valine | 1987 |
Bursting in human epileptogenic neocortex is depressed by an N-methyl-D-aspartate antagonist.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Anticonvulsants; Aspartic Acid; Epilepsy, Temporal Lobe; Humans; In Vitro Techniques; N-Methylaspartate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Temporal Lobe; Valine | 1987 |
N-methyl-D-aspartate receptor antagonist desegregates eye-specific stripes.
Topics: 2-Amino-5-phosphonovalerate; Afferent Pathways; Animals; Aspartic Acid; Evoked Potentials, Visual; N-Methylaspartate; Rana pipiens; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Superior Colliculi; Valine | 1987 |
The novel anticonvulsant MK-801 binds to the activated state of the N-methyl-D-aspartate receptor in rat brain.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Aspartic Acid; Brain; Dibenzocycloheptenes; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; In Vitro Techniques; N-Methylaspartate; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Synaptic Membranes; Valine | 1987 |
Respiratory and vasomotor effects of excitatory amino acid on ventral medullary surface.
Topics: 2-Amino-5-phosphonovalerate; Animals; Apnea; Aspartic Acid; Blood Pressure; Carotid Sinus; Cats; Female; Glutamates; Kainic Acid; Male; Medulla Oblongata; N-Methylaspartate; Oxadiazoles; Phrenic Nerve; Quisqualic Acid; Respiration; Vagotomy; Valine; Vasomotor System | 1987 |
Postnatal development of the chemosensitivity of rat cerebellar Purkinje cells to excitatory amino acids. An in vitro study.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Cerebellar Cortex; Glutamates; Glutamic Acid; In Vitro Techniques; N-Methylaspartate; Oxadiazoles; Purkinje Cells; Quisqualic Acid; Rats; Rats, Inbred Strains; Reaction Time; Valine | 1987 |
Excitatory amino acid-induced release of 3H-GABA from cultured mouse cerebral cortex interneurons.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Binding Sites; Cerebral Cortex; gamma-Aminobutyric Acid; Kainic Acid; Mice; N-Methylaspartate; Neurons; Oxadiazoles; Potassium; Quisqualic Acid; Valine | 1987 |
Effects of ketamine on the in vivo toxicity of quinolinate and N-methyl-D-aspartate in the rat hippocampus.
Topics: 2-Amino-5-phosphonovalerate; Anesthesia, General; Animals; Aspartic Acid; Drug Interactions; Female; Halothane; Hippocampus; Ketamine; N-Methylaspartate; Pentobarbital; Pyridines; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains; Valine | 1987 |
Inhibition of N-methyl-D-aspartate-induced hippocampal [3H]norepinephrine release by phencyclidine is dependent on potassium concentration.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Hippocampus; In Vitro Techniques; Magnesium Sulfate; Male; N-Methylaspartate; Norepinephrine; Phencyclidine; Potassium; Rats; Rats, Inbred Strains; Valine | 1987 |
A role for the ventral surface of the medulla in regulation of nasal resistance.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Airway Resistance; Animals; Aspartic Acid; Blood Pressure; Cats; Lidocaine; Medulla Oblongata; N-Methylaspartate; Nose; Phrenic Nerve; Receptors, Amino Acid; Receptors, Neurotransmitter; Valine | 1987 |
Effects of ketamine and (+)cyclazocine on 4-aminopyridine and "magnesium free" epileptogenic activity in hippocampal slices of rats.
Topics: 2-Amino-5-phosphonovalerate; 4-Aminopyridine; Aminopyridines; Animals; Aspartic Acid; Cyclazocine; Epilepsy; Hippocampus; Ketamine; Magnesium; Male; N-Methylaspartate; Rats; Rats, Inbred Strains; Synaptic Transmission; Valine | 1987 |
Dual action of excitatory amino acids on the metabolism of inositol phosphates in striatal neurons.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Carbachol; Cells, Cultured; Corpus Striatum; Glutamates; Inositol Phosphates; Mice; N-Methylaspartate; Neurons; Oxadiazoles; Quisqualic Acid; Sugar Phosphates; Valine | 1987 |
Intrathecal N-methyl-D-aspartate (NMDA) activates both nociceptive and antinociceptive systems.
Topics: 2-Amino-5-phosphonovalerate; Analgesia; Animals; Aspartic Acid; Behavior, Animal; Decerebrate State; Injections, Spinal; Male; N-Methylaspartate; Nociceptors; Pain; Rats; Valine | 1987 |
The effects of excitatory amino acids and their antagonists on the generation of motor activity in the isolated chick spinal cord.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Chick Embryo; Convulsants; Dipeptides; In Vitro Techniques; Kynurenic Acid; Motor Activity; Motor Neurons; N-Methylaspartate; Spinal Cord; Valine | 1987 |
Pharmacology of glutamate neurotoxicity in cortical cell culture: attenuation by NMDA antagonists.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Cells, Cultured; Cerebral Cortex; Glutamates; Glutamic Acid; Isomerism; Kainic Acid; Mice; N-Methylaspartate; Neurons; Neurotoxins; Oxadiazoles; Quisqualic Acid; Valine | 1988 |
Epileptiform activity induced by alkalosis in rat neocortical slices: block by antagonists of N-methyl-D-aspartate.
Topics: 2-Amino-5-phosphonovalerate; Alkalosis; Animals; Aspartic Acid; Cerebral Cortex; Epilepsy; In Vitro Techniques; Ketamine; Magnesium Deficiency; N-Methylaspartate; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine | 1987 |
The pharmacological selectivity of three NMDA antagonists.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Aspartic Acid; Dibenzocycloheptenes; Dizocilpine Maleate; Hexamethonium Compounds; In Vitro Techniques; Motor Neurons; N-Methylaspartate; Norepinephrine; Piperazines; Rats; Serotonin; Synaptic Transmission; Valine | 1988 |
A novel interaction between dynorphin(1-13) and an N-methyl-D-aspartate site.
Topics: 2-Amino-5-phosphonovalerate; Analgesics; Animals; Aspartic Acid; Atropine; Binding, Competitive; Dipeptides; Dynorphins; Hot Temperature; Kinetics; Male; N-Methylaspartate; Pain; Peptide Fragments; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine | 1988 |
A quantitative pharmacological analysis of some excitatory amino acid receptors in the mouse neocortex in vitro.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Cerebral Cortex; Ibotenic Acid; In Vitro Techniques; Kynurenic Acid; Male; Mice; N-Methylaspartate; Quinolinic Acid; Quinolinic Acids; Receptors, Amino Acid; Receptors, Cell Surface; Valine | 1988 |
An excitatory amino acid projection from ventromedial hypothalamus to periaqueductal gray in the rat: autoradiographic and electrophysiological evidence.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Animals; Aspartic Acid; Autoradiography; Electric Stimulation; Kainic Acid; Male; N-Methylaspartate; Neural Pathways; Periaqueductal Gray; Rats; Rats, Inbred Strains; Reaction Time; Valine; Ventromedial Hypothalamic Nucleus | 1988 |
Dextrorphan and dextromethorphan, common antitussives, are antiepileptic and antagonize N-methyl-D-aspartate in brain slices.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Antitussive Agents; Aspartic Acid; Cerebral Cortex; Dextromethorphan; Dextrorphan; Evoked Potentials; Guinea Pigs; In Vitro Techniques; Levorphanol; Morphinans; N-Methylaspartate; Seizures; Valine | 1988 |
Solubilization of rat brain phencyclidine receptors in an active binding form that is sensitive to N-methyl-D-aspartate receptor ligands.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Binding, Competitive; Brain Chemistry; Cell Membrane; Cholic Acid; Cholic Acids; Detergents; Glutamates; Glutamic Acid; Male; N-Methylaspartate; Phencyclidine; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Receptors, Phencyclidine; Solubility; Valine | 1988 |
NMDA- and kainate-evoked GABA release from striatal neurones differentiated in primary culture: differential blocking by phencyclidine.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Cells, Cultured; Corpus Striatum; gamma-Aminobutyric Acid; Kainic Acid; Mice; N-Methylaspartate; Phencyclidine; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine | 1988 |
Quinolinic acid effects on amino acid release from the rat cerebral cortex in vitro and in vivo.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Aspartic Acid; Cerebral Cortex; In Vitro Techniques; Kainic Acid; Male; N-Methylaspartate; Pyridines; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains; Valine | 1988 |
Differential control by N-methyl-D-aspartate and kainate of striatal dopamine release in vivo: a trans-striatal dialysis study.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Atropine; Carbachol; Corpus Striatum; Dopamine; Kainic Acid; Male; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Rats; Rats, Inbred Strains; Tetrodotoxin; Valine | 1988 |
Amino acids modulate calcium permeability of the plasma membrane of human neuroblastoma cells.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Aspartic Acid; Calcium; Cell Membrane Permeability; Cysteine; Humans; Kainic Acid; N-Methylaspartate; Neuroblastoma; Neurotransmitter Agents; Tumor Cells, Cultured; Valine | 1988 |
Effects of excitatory amino acids on the oxygen consumption of hippocampal slices from the guinea pig.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Amino Acids; Animals; Aspartic Acid; Glutamates; Guinea Pigs; Hippocampus; In Vitro Techniques; Kainic Acid; N-Methylaspartate; Oxadiazoles; Oxygen Consumption; Quisqualic Acid; Receptors, Amino Acid; Receptors, Cell Surface; Spider Venoms; Valine | 1988 |
Influence of dynorphin (1-13) on spinal reflexes in the rat.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Dynorphins; Electrophysiology; Injections, Spinal; Male; N-Methylaspartate; Nerve Fibers; Peptide Fragments; Rats; Rats, Inbred Strains; Receptors, Opioid; Reflex; Spinal Cord; Valine | 1988 |
Quantitative correlation between tetanus-induced decreases in extracellular calcium and LTP.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Animals; Aspartic Acid; Calcium; Electric Stimulation; Extracellular Space; Hippocampus; In Vitro Techniques; Male; N-Methylaspartate; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine | 1988 |
Differential effects of N-methyl-D-aspartic acid and L-homocysteic acid on cerebellar Purkinje neurons.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Amino Acids; Animals; Aspartic Acid; Dipeptides; Glutamates; Homocysteine; Iontophoresis; Ketamine; Male; N-Methylaspartate; Purkinje Cells; Rats; Rats, Inbred Strains; Valine | 1988 |
Glycine reverses antagonism of N-methyl-D-aspartate (NMDA) by 1-hydroxy-3-aminopyrrolidone-2 (HA-966) but not by D-2-amino-5-phosphonovalerate (D-AP5) on rat cortical slices.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Aspartic Acid; Cerebral Cortex; Evoked Potentials; Glycine; In Vitro Techniques; N-Methylaspartate; Pyrrolidinones; Rats; Valine | 1988 |
Excitatory amino acid receptors expressed in Xenopus oocytes: agonist pharmacology.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Chlorides; Female; Ibotenic Acid; Kainic Acid; Membrane Potentials; N-Methylaspartate; Oocytes; Oxadiazoles; Quisqualic Acid; Rats; Receptors, AMPA; Receptors, Drug; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine; Xenopus | 1988 |
An intracellular analysis of amino acid induced excitations of deep dorsal horn neurones in the rat spinal cord slice.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Electrophysiology; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; In Vitro Techniques; Intracellular Membranes; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Rats; Spinal Cord; Tetrodotoxin; Valine | 1988 |
Glutamate stimulates somatostatin release from diencephalic neurons in primary culture.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Cells, Cultured; Diencephalon; Glutamates; Glutamic Acid; Kainic Acid; Magnesium; N-Methylaspartate; Neurons; Oxadiazoles; Phencyclidine; Potassium; Quisqualic Acid; Rats; Somatostatin; Tetrodotoxin; Valine; Veratridine | 1988 |
Sites of antagonist action on N-methyl-D-aspartic acid receptors studied using fluctuation analysis and a rapid perfusion technique.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Binding Sites; Binding, Competitive; Cations, Divalent; Cells, Cultured; Glycine; Hippocampus; Ketamine; Kynurenic Acid; Magnesium; Mice; Mice, Inbred C57BL; N-Methylaspartate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine; Zinc | 1988 |
Epileptiform bursts elicited in CA3 hippocampal neurons by a variety of convulsants are not blocked by N-methyl-D-aspartate antagonists.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Amino Acids; Animals; Anticonvulsants; Aspartic Acid; Convulsants; Hippocampus; In Vitro Techniques; Kainic Acid; Kindling, Neurologic; N-Methylaspartate; Piperazines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine | 1988 |
Behavioral classification of excitatory amino acid receptors in mouse spinal cord.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Behavior, Animal; Glutamates; Glutamic Acid; Glutamine; Kainic Acid; Male; Mice; Mice, Inbred ICR; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Receptors, Amino Acid; Receptors, Cell Surface; Spinal Cord; Valine | 1988 |
Glycine potentiates strychnine-induced convulsions: role of NMDA receptors.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Drug Synergism; Glycine; Injections, Spinal; Mice; N-Methylaspartate; Receptors, Amino Acid; Receptors, Cell Surface; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Seizures; Strychnine; Valine | 1988 |
Long-term potentiation differentially affects two components of synaptic responses in hippocampus.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Evoked Potentials, Somatosensory; Hippocampus; In Vitro Techniques; Membrane Potentials; N-Methylaspartate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Reference Values; Synapses; Valine | 1988 |
Kynurenic acid and AP5 distinguish between NMDA receptor agonists.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Dose-Response Relationship, Drug; Ibotenic Acid; Kynurenic Acid; Mice; N-Methylaspartate; Quinolinic Acid; Quinolinic Acids; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine | 1988 |
Do N-methyl-D-aspartate receptors mediate synaptic responses in the mudpuppy retina?
Topics: 2-Amino-5-phosphonovalerate; Aminobutyrates; Animals; Aspartic Acid; Electroretinography; Light; N-Methylaspartate; Necturus maculosus; Neurons; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Retina; Retinal Ganglion Cells; Stereoisomerism; Synapses; Valine | 1988 |
Amino acid pharmacology in neocortical slices: evidence for bimolecular actions from an extension of the Hill and Gaddum-Schild equations.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Cerebral Cortex; In Vitro Techniques; Kynurenic Acid; Mathematics; Mice; N-Methylaspartate; Pyridines; Quinolinic Acids; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine | 1988 |
A comparison between the in vivo and in vitro activity of five potent and competitive NMDA antagonists.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Aspartic Acid; Binding, Competitive; In Vitro Techniques; N-Methylaspartate; Neurons; Piperazines; Rats; Reflex; Spine; Valine | 1988 |
NMDA receptor blockade prevents the increase in protein kinase C substrate (protein F1) phosphorylation produced by long-term potentiation.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Aspartic Acid; GAP-43 Protein; Hippocampus; Kinetics; Membrane Proteins; N-Methylaspartate; Nerve Tissue Proteins; Phosphoproteins; Phosphorylation; Protein Kinase C; Rats; Reference Values; Valine | 1988 |
Quisqualate, kainate and NMDA can initiate spreading depression in the turtle cerebellum.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Animals; Aspartic Acid; Cerebellum; Electric Stimulation; In Vitro Techniques; Kainic Acid; Magnesium; N-Methylaspartate; Neural Inhibition; Oxadiazoles; Quisqualic Acid; Turtles; Valine | 1988 |
N-methyl-D-aspartate promotes the survival of cerebellar granule cells in culture.
Topics: 2-Amino-5-phosphonovalerate; Animals; Antigens, Surface; Aspartic Acid; Cell Adhesion Molecules; Cell Survival; Cells, Cultured; Cerebellum; N-Methylaspartate; Nerve Tissue Proteins; Potassium; Rats; Rats, Inbred Strains; Valine | 1988 |
Stimulation of NMDA receptors induces proteolysis of spectrin in hippocampus.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Aspartic Acid; Calcium Chloride; Evoked Potentials; Hippocampus; Hydrolysis; In Vitro Techniques; N-Methylaspartate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Spectrin; Valine | 1988 |
D-aminophosphonovaleric acid-sensitive spontaneous giant EPSPs in immature rat hippocampal neurones.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Electric Stimulation; Hippocampus; In Vitro Techniques; Male; N-Methylaspartate; Neurons; Piperazines; Rats; Synapses; Tetrodotoxin; Valine | 1988 |
Evidence for a specific role for cortical NMDA receptors in slow-wave sleep.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Animals; Aspartic Acid; Cerebral Cortex; Iontophoresis; Male; N-Methylaspartate; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Sleep; Valine | 1988 |
Phosphonate analogues of carboxylic acids as aminoacid antagonists on rat cortical neurones.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Cerebral Cortex; Drug Antagonism; Electric Conductivity; Glutamates; Glutamic Acid; Isomerism; Kainic Acid; N-Methylaspartate; Neurons; Organophosphorus Compounds; Rats; Valine | 1981 |
D-aminophosphonovalerate is 100-fold more powerful than D-alpha-aminoadipate in blocking N-methylaspartate neurotoxicity.
Topics: 2-Amino-5-phosphonovalerate; 2-Aminoadipic Acid; Amino Acids, Dicarboxylic; Animals; Aspartic Acid; Female; Hypothalamus; Male; Mice; N-Methylaspartate; Neurons; Organophosphorus Compounds; Structure-Activity Relationship; Valine | 1981 |
Some effects of excitatory amino acid receptor antagonists on synaptic transmission in the rat olfactory cortex slice.
Topics: 2-Amino-5-phosphonovalerate; Aminobutyrates; Animals; Aspartic Acid; Culture Techniques; Dipeptides; Electric Stimulation; Evoked Potentials; N-Methylaspartate; Olfactory Bulb; Olfactory Pathways; Pipecolic Acids; Rats; Receptors, Amino Acid; Receptors, Cell Surface; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Synapses; Synaptic Transmission; Valine | 1982 |
Actions of N-methyl aspartate and its antagonist aminophosphonovalerate on the A5 catecholamine cell group in rat.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Blood Pressure; Brain; Dose-Response Relationship, Drug; Female; Heart Rate; Male; N-Methylaspartate; Neurons; Rats; Receptors, Adrenergic; Receptors, Cell Surface; Receptors, N-Methyl-D-Aspartate; Valine | 1982 |
Characterization of the excitatory amino acid receptor-mediated release of [3H]acetylcholine from rat striatal slices.
Topics: 2-Amino-5-phosphonovalerate; Acetylcholine; Afferent Pathways; Animals; Aspartic Acid; Cerebral Cortex; Corpus Striatum; Dose-Response Relationship, Drug; Glutamates; Glutamic Acid; Hippocampus; Interneurons; Magnesium; Male; N-Methylaspartate; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, Cell Surface; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission; Valine | 1982 |
Effects of the glutamate analogue AMPA and its interaction with antagonists on cultured rat spinal and brain stem neurones.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Brain Stem; Cells, Cultured; Embryo, Mammalian; Glutamates; Ibotenic Acid; N-Methylaspartate; Oxazoles; Rats; Receptors, Cell Surface; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Valine | 1983 |
The antagonism of amino acid-induced excitations of rat hippocampal CA1 neurones in vitro.
Topics: 2-Amino-5-phosphonovalerate; 2-Aminoadipic Acid; Action Potentials; Amino Acids; Animals; Aspartic Acid; Dipeptides; Hippocampus; In Vitro Techniques; Kainic Acid; Male; N-Methylaspartate; Neurons; Oxadiazoles; Quisqualic Acid; Rats; Valine | 1983 |
Blockade of amino acid-induced depolarizations and inhibition of excitatory post-synaptic potentials in rat dentate gyrus.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Dipeptides; Evoked Potentials; Hippocampus; In Vitro Techniques; Kainic Acid; Membrane Potentials; N-Methylaspartate; Oxadiazoles; Pipecolic Acids; Quisqualic Acid; Rats; Synapses; Valine | 1983 |
A comparison of the anticonvulsant potency of (+/-) 2-amino-5-phosphonopentanoic acid and (+/-) 2-amino-7-phosphonoheptanoic acid.
Topics: 2-Amino-5-phosphonovalerate; Acoustic Stimulation; Amino Acids; Animals; Anticonvulsants; Aspartic Acid; Cerebral Cortex; Male; Mice; Mice, Inbred DBA; N-Methylaspartate; Rats; Rats, Inbred Strains; Seizures; Valine | 1983 |
Amino acid neurotransmission between fimbria-fornix fibers and neurons in the lateral septum of the rat: a microiontophoretic study.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Excitatory Amino Acid Antagonists; Glutamates; Hippocampus; Iontophoresis; Male; N-Methylaspartate; Nerve Fibers; Neural Pathways; Neuromuscular Junction; Oxadiazoles; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, Cell Surface; Septal Nuclei; Synaptic Transmission; Valine | 1984 |
A comparison of the effects of N-methyl-D-aspartate and quinolinate on central neurones of the rat.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Iontophoresis; Microinjections; N-Methylaspartate; Neurons; Oxadiazoles; Pyridines; Quinolinic Acid; Quinolinic Acids; Quisqualic Acid; Rats; Somatosensory Cortex; Spinal Cord; Stimulation, Chemical; Valine | 1984 |
Mixed-agonist action of excitatory amino acids on mouse spinal cord neurones under voltage clamp.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Culture Techniques; Electric Conductivity; Glutamates; Glutamic Acid; Homocysteine; Kainic Acid; Membrane Potentials; Mice; Mice, Inbred C57BL; N-Methylaspartate; Neurons; Oxadiazoles; Quisqualic Acid; Spinal Cord; Valine | 1984 |
N-methyl-D-aspartic acid/glycine interactions on the control of 5-hydroxytryptamine release in raphe primary cultures.
Topics: Animals; Cells, Cultured; Embryo, Mammalian; Female; Gestational Age; Glutamates; Glutamic Acid; Glycine; Kinetics; Kynurenic Acid; N-Methylaspartate; Pregnancy; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Rhombencephalon; Serotonin; Strychnine; Valine | 1993 |
The competitive NMDA antagonist MDL-100,453 reduces infarct size after experimental stroke.
Topics: Animals; Blood Pressure; Body Temperature; Brain; Carbon Dioxide; Cerebral Arteries; Cerebral Infarction; Infusion Pumps; Injections, Intravenous; Ischemic Attack, Transient; Male; N-Methylaspartate; Pilot Projects; Placebos; Rats; Rats, Sprague-Dawley; Valine | 1994 |
[Effect of intracerebroventricular injection of N-methyl-D-aspartate on learning and memory in mice].
Topics: Animals; Female; Injections, Intraventricular; Learning; Male; Memory; Mice; N-Methylaspartate; Valine | 1993 |
Opposing effects on blood pressure following the activation of metabotropic and ionotropic glutamate receptors in raphe obscurus in the anaesthetized rat.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Analysis of Variance; Animals; Benzoates; Blood Pressure; Cycloleucine; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Hypertension; Male; Microinjections; N-Methylaspartate; Neurotoxins; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Structure-Activity Relationship; Valine | 1996 |
NMDA receptor-mediated increase in cyclic GMP in the rat cerebellum in vivo is blocked by alaproclate and GEA-857.
Topics: 4-Aminopyridine; Alanine; Animals; Behavior, Animal; Cerebellum; Convulsants; Cyclic GMP; Drug Interactions; Harmaline; Male; N-Methylaspartate; Pentylenetetrazole; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Seizures; Selective Serotonin Reuptake Inhibitors; Valine | 1997 |
Mossy fibre innervation is not required for the development of kainic acid toxicity in organotypic hippocampal slice cultures.
Topics: Animals; Cell Death; Cell Survival; Hippocampus; In Vitro Techniques; Kainic Acid; Microelectrodes; Mossy Fibers, Hippocampal; N-Methylaspartate; Neural Pathways; Pyramidal Cells; Quinoxalines; Rats; Rats, Wistar; Receptors, Glutamate; Time Factors; Valine | 1998 |
Effects of lesions to the glutamatergic afferents to the nucleus accumbens in the modulation of reactivity to spatial and non-spatial novelty in mice.
Topics: Afferent Pathways; Amygdala; Animals; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Exploratory Behavior; Glutamic Acid; Hippocampus; Ibotenic Acid; Injections; Limbic System; Mice; Models, Neurological; Motor Activity; N-Methylaspartate; Nucleus Accumbens; Spatial Behavior; Valine | 1999 |
Chlormethiazole inhibits epileptiform activity by potentiating GABA(A) receptor function.
Topics: Action Potentials; Animals; Bicuculline; Cerebral Cortex; Chlormethiazole; Dose-Response Relationship, Drug; Epilepsy; gamma-Aminobutyric Acid; Male; N-Methylaspartate; Neurons; Neuroprotective Agents; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Tetrodotoxin; Valine | 2000 |
NiCl2 and amiloride induce spreading depression in guinea pig hippocampal slices.
Topics: Amiloride; Animals; Calcium Channel Blockers; Calcium Channels, T-Type; Cortical Spreading Depression; Dose-Response Relationship, Drug; Electrophysiology; Guinea Pigs; Hippocampus; In Vitro Techniques; N-Methylaspartate; Nickel; Valine | 2000 |
NMDA-responsible, APV-insensitive receptor in cultured human astrocytes.
Topics: Astrocytes; Calcium; Cells, Cultured; Glial Fibrillary Acidic Protein; Glycine; GTP-Binding Proteins; Humans; N-Methylaspartate; Receptors, N-Methyl-D-Aspartate; Valine | 2001 |
MAP2 phosphorylation and visual plasticity in Xenopus.
Topics: Aging; Animals; Dendrites; Dose-Response Relationship, Drug; Drug Administration Schedule; Excitatory Amino Acid Agonists; Glutamic Acid; Immunoblotting; Microtubule-Associated Proteins; N-Methylaspartate; Neuronal Plasticity; Phosphorylation; Receptors, N-Methyl-D-Aspartate; Superior Colliculi; Valine; Vision, Binocular; Visual Pathways; Xenopus laevis | 2001 |
Distinct NMDA receptors provide differential modes of transmission at mossy fiber-interneuron synapses.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anticonvulsants; Calcium; Chlorides; Cyclopropanes; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glycine; Hippocampus; In Vitro Techniques; Interneurons; Mossy Fibers, Hippocampal; N-Methylaspartate; Patch-Clamp Techniques; Phenols; Piperidines; Polyamines; Protein Subunits; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission; Valine | 2002 |
Conformational change in aspartate aminotransferase on substrate binding induces strain in the catalytic group and enhances catalysis.
Topics: Aspartate Aminotransferases; Aspartic Acid; Binding Sites; Catalysis; Escherichia coli; Glycine; Hydrogen-Ion Concentration; Kinetics; Ligands; Lysine; Malates; Models, Chemical; Models, Molecular; Mutagenesis, Site-Directed; Mutation; N-Methylaspartate; Oxygen; Photons; Plasmids; Protein Binding; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Spectrophotometry; Tyrosine; Valine | 2003 |
Functional NMDA receptor channels generated by NMDAR2B gene transfer in rat cerebellar Purkinje cells.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Cells, Cultured; Cerebellum; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Gene Transfer Techniques; Genetic Vectors; Green Fluorescent Proteins; Immunohistochemistry; Infections; Luminescent Proteins; Magnesium; N-Methylaspartate; Patch-Clamp Techniques; Purkinje Cells; Rats; Receptors, N-Methyl-D-Aspartate; Sindbis Virus; Valine | 2003 |
How does prolonged caloric restriction ameliorate age-related impairment of long-term potentiation in the hippocampus?
Topics: 2-Amino-5-phosphonovalerate; Aging; Animals; Arachidonic Acid; Calcium; Calcium Signaling; Caloric Restriction; Docosahexaenoic Acids; Excitatory Amino Acid Antagonists; Fatty Acids, Unsaturated; Food Deprivation; Hippocampus; Long-Term Potentiation; Male; Membrane Lipids; N-Methylaspartate; Neural Pathways; Neurons; Organ Culture Techniques; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission; Valine | 2003 |
Stimulation of luteinizing hormone secretion by N-methyl-D,L-aspartic acid in the adult male guinea-pig: incomplete blockade by gonadotropin-releasing hormone receptor antagonism.
Topics: Animals; Gonadotropin-Releasing Hormone; Guinea Pigs; Luteinizing Hormone; Male; N-Methylaspartate; Receptors, LHRH; Valine | 2003 |
Serotonin type II receptor activation facilitates synaptic plasticity via N-methyl-D-aspartate-mediated mechanism in the rat basolateral amygdala.
Topics: Amygdala; Animals; Calcium; Dose-Response Relationship, Drug; Drug Synergism; Electric Stimulation; Excitatory Amino Acid Agonists; Fluorescent Dyes; Fura-2; Glycine; In Vitro Techniques; Indophenol; Ketanserin; Magnesium; Male; Membrane Potentials; N-Methylaspartate; Neuronal Plasticity; Rats; Rats, Sprague-Dawley; Serotonin Antagonists; Serotonin Receptor Agonists; Spiro Compounds; Sulfonamides; Synaptic Transmission; Time Factors; Valine | 2003 |
Transduction of light in the suprachiasmatic nucleus: evidence for two different neurochemical cascades regulating the levels of Per1 mRNA and pineal melatonin.
Topics: Animals; Autoradiography; Cricetinae; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Gene Expression Regulation; Light; Male; Melatonin; Microinjections; N-Methylaspartate; Nuclear Proteins; Pineal Gland; Quinoxalines; Radioimmunoassay; RNA, Messenger; Suprachiasmatic Nucleus; Valine | 2003 |
Implications for hyperhomocysteinemia: not homocysteine but its oxidized forms strongly inhibit neuronal network activity.
Topics: Action Potentials; Animals; Cells, Cultured; Dose-Response Relationship, Drug; Drug Combinations; Drug Interactions; Electric Stimulation; Electrophysiology; Embryo, Mammalian; Homocysteine; Hyperhomocysteinemia; N-Methylaspartate; Neocortex; Nerve Net; Neural Inhibition; Rats; Rats, Wistar; Valine | 2004 |
A proportional but slower NMDA potentiation follows AMPA potentiation in LTP.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Cells, Cultured; Drug Synergism; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; In Vitro Techniques; Long-Term Potentiation; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Quinoxalines; Rats; Receptors, AMPA; Sodium Channel Blockers; Synapses; Tetrodotoxin; Time Factors; Transfection; Valine; Visual Cortex | 2004 |
A molecular technique for detecting the liberation of intracellular zinc in cultured neurons.
Topics: Animals; Cadmium; Cells, Cultured; Cerebral Cortex; DNA-Binding Proteins; Dose-Response Relationship, Drug; Drug Interactions; Embryo, Mammalian; Enzyme Activation; Excitatory Amino Acid Agonists; Gene Expression Regulation, Enzymologic; Genes, Reporter; Intracellular Space; Luciferases; Models, Neurological; Molecular Probe Techniques; N-Methylaspartate; Neurons; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Transcription Factor MTF-1; Transcription Factors; Valine; Zinc | 2004 |
Tetanization-induced pelvic-to-pudendal reflex plasticity in anesthetized rats.
Topics: Animals; Bicuculline; Decerebrate State; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; GABA Antagonists; GABA-A Receptor Antagonists; Glutamic Acid; Long-Term Potentiation; N-Methylaspartate; Nervous System Physiological Phenomena; Neuronal Plasticity; Pelvis; Quinoxalines; Rats; Rats, Wistar; Reflex; Valine | 2004 |
Role of N-methyl-D-aspartate receptors in gastric mucosal blood flow induced by histamine.
Topics: Acids; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Aspartic Acid; Cimetidine; Drug Interactions; Gastric Mucosa; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; Immunohistochemistry; Laser-Doppler Flowmetry; Male; N-Methylaspartate; Prazosin; Propranolol; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Regional Blood Flow; Time Factors; Tripelennamine; Valine; Yohimbine | 2004 |
Quaternary structure, protein dynamics, and synaptic function of SAP97 controlled by L27 domain interactions.
Topics: Adaptor Proteins, Signal Transducing; Analysis of Variance; Animals; Baculoviridae; Biophysics; Brain; Cells, Cultured; Chromatography, Gel; Dendritic Spines; Discs Large Homolog 1 Protein; Disks Large Homolog 4 Protein; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Gene Expression Regulation; Genetic Vectors; Guanylate Kinases; Humans; Immunohistochemistry; In Vitro Techniques; Insecta; Intracellular Signaling Peptides and Proteins; Lentivirus; Long-Term Potentiation; Membrane Proteins; Mice; Microscopy, Confocal; Microscopy, Electron, Scanning; Microscopy, Energy-Filtering Transmission Electron; Mutagenesis; N-Methylaspartate; Nerve Tissue Proteins; Neurons; Patch-Clamp Techniques; Protein Structure, Tertiary; Rats; Receptors, AMPA; Recombinant Fusion Proteins; RNA, Antisense; RNA, Small Interfering; Sequence Alignment; Synapses; Synaptic Transmission; Time Factors; Transfection; Valine | 2004 |
GluR- and TrkB-mediated maturation of GABA receptor function during the period of eye opening.
Topics: Age Factors; Animals; Animals, Newborn; Blotting, Northern; Brain-Derived Neurotrophic Factor; Dizocilpine Maleate; Embryo, Mammalian; Eye; GABA Agonists; Gene Expression Regulation, Developmental; In Vitro Techniques; Mice; Mice, Knockout; N-Methylaspartate; Neural Inhibition; Neurons; Patch-Clamp Techniques; Pyridines; Rats; Rats, Wistar; Receptor, trkB; Receptors, GABA-A; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Superior Colliculi; Synapses; Synaptic Transmission; Valine; Zolpidem | 2005 |
Kinetics and subunit composition of NMDA receptors in respiratory-related neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Blotting, Northern; Brain Stem; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; In Vitro Techniques; Membrane Potentials; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Protein Subunits; Rats; Receptors, N-Methyl-D-Aspartate; Respiration; Restraint, Physical; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Valine | 2005 |
Long-term depression at olfactory nerve synapses.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Calcium; Diagnostic Imaging; Dopamine Antagonists; Dose-Response Relationship, Radiation; Drug Interactions; Electric Stimulation; Evoked Potentials; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glycine; In Vitro Techniques; Long-Term Synaptic Depression; Methoxyhydroxyphenylglycol; Mice; Mice, Inbred ICR; N-Methylaspartate; Neurons; Olfactory Bulb; Patch-Clamp Techniques; Quinoxalines; Sodium Channel Blockers; Sulpiride; Synapses; Tetrodotoxin; Time Factors; Valine | 2005 |
Hippocalcin-deficient mice display a defect in cAMP response element-binding protein activation associated with impaired spatial and associative memory.
Topics: Animals; Association Learning; Avoidance Learning; Behavior, Animal; Blotting, Western; Brain; Cadmium Chloride; Calcium Channel Blockers; Calcium-Binding Proteins; Choice Behavior; Cognition Disorders; Cyclic AMP Response Element-Binding Protein; Discrimination Learning; Dizocilpine Maleate; Drug Interactions; Electric Stimulation; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Flavonoids; Hippocalcin; Hippocampus; Immunohistochemistry; In Vitro Techniques; Male; Maze Learning; Mice; Mice, Knockout; Motor Activity; N-Methylaspartate; Nerve Tissue Proteins; Nimodipine; Phosphorylation; Potassium Chloride; Psychomotor Performance; Reaction Time; Rotarod Performance Test; Spatial Behavior; Valine | 2005 |
BDNF-induced facilitation of afferent-evoked responses in lamina II neurons is reduced after neonatal spinal cord contusion injury.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Afferent Pathways; Age Factors; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Brain-Derived Neurotrophic Factor; Dose-Response Relationship, Radiation; Electric Stimulation; Evoked Potentials; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; In Vitro Techniques; Lamin Type B; Membrane Potentials; N-Methylaspartate; Neurons; Rats; Rats, Sprague-Dawley; Spinal Cord; Spinal Cord Injuries; Synaptic Transmission; Valine | 2005 |
Spine-neck geometry determines NMDA receptor-dependent Ca2+ signaling in dendrites.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Calcium; Calcium Signaling; Dendritic Spines; Diagnostic Imaging; Dose-Response Relationship, Radiation; Glutamates; Hippocampus; In Vitro Techniques; Indoles; Lasers; Membrane Potentials; Models, Neurological; N-Methylaspartate; Patch-Clamp Techniques; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission; Valine | 2005 |
Rap2-JNK removes synaptic AMPA receptors during depotentiation.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Blotting, Western; Cells, Cultured; Drug Interactions; Electric Stimulation; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Fluorescent Antibody Technique; Gene Expression Regulation; Green Fluorescent Proteins; Hippocampus; In Vitro Techniques; JNK Mitogen-Activated Protein Kinases; Long-Term Synaptic Depression; Magnesium; Models, Neurological; Mutagenesis; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Phosphorylation; rap GTP-Binding Proteins; Rats; Receptors, AMPA; Recombinant Proteins; Synaptic Transmission; Time Factors; Transfection; Valine | 2005 |
Effects of glutamate transporter and receptor ligands on neuronal glutamate uptake.
Topics: Amino Acid Transport System X-AG; Animals; Animals, Newborn; Aspartic Acid; Cells, Cultured; Cerebellum; Cycloleucine; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Ligands; N-Methylaspartate; Naphthalenes; Neurons; Neuroprotective Agents; Oxepins; Rats; Rats, Wistar; Receptors, Glutamate; Tritium; Valine | 2005 |
Frequency-dependent impairment of hippocampal LTP from NMDA receptors with reduced calcium permeability.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Dose-Response Relationship, Radiation; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; Hippocampus; Integrases; Long-Term Potentiation; Mice; Mice, Inbred C57BL; Mice, Transgenic; N-Methylaspartate; Patch-Clamp Techniques; Receptors, N-Methyl-D-Aspartate; Valine | 2005 |
Effects of agonists and antagonists of NMDA and ACh receptors on plasticity of bat auditory system elicited by fear conditioning.
Topics: Acetylcholine; Acoustic Stimulation; Action Potentials; Animals; Atropine; Auditory Cortex; Auditory Pathways; Chiroptera; Cholinergic Agonists; Cholinergic Antagonists; Drug Interactions; Electric Stimulation; Fear; Inferior Colliculi; N-Methylaspartate; Neuronal Plasticity; Time Factors; Valine | 2005 |
Role of AMPA receptor desensitization and the side effects of a DMSO vehicle on reticulospinal EPSPs and locomotor activity.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Analgesics, Non-Narcotic; Animals; Behavior, Animal; Benzothiadiazines; Dimethyl Sulfoxide; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Lampreys; Motor Activity; N-Methylaspartate; Nerve Net; Neural Networks, Computer; Neurons; Receptors, AMPA; Spinal Cord; Synapses; Valine | 2005 |
Effects of brain-derived neurotrophic factor (BDNF) on activity mediated by NMDA receptors in rat spinal cord cultures.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Anesthetics, Local; Animals; Antibodies; Brain-Derived Neurotrophic Factor; Drug Administration Schedule; Drug Interactions; Embryo, Mammalian; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; N-Methylaspartate; Neural Inhibition; Neurons; Organ Culture Techniques; Rats; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Tetrodotoxin; Valine | 2005 |
Depression of extra-cellular GABA and increase of NMDA-induced nitric oxide following acute intra-nuclear administration of alcohol in the cerebellar nuclei of the rat.
Topics: Animals; Central Nervous System Depressants; Cerebellar Nuclei; Enzyme Inhibitors; Ethanol; Excitatory Amino Acid Antagonists; Extracellular Fluid; GABA Agonists; gamma-Aminobutyric Acid; Indazoles; Injections, Intraventricular; Male; Microdialysis; N-Methylaspartate; Nipecotic Acids; Nitric Oxide; Quinoxalines; Rats; Rats, Wistar; Tiagabine; Valine | 2005 |
Effect of NMDA antagonists on the death of cerebellar granule neurons at different ages.
Topics: Age Factors; Animals; Animals, Newborn; Apoptosis; Carbachol; Caspase 3; Caspases; Cells, Cultured; Cerebellum; Cholinergic Agonists; Dizocilpine Maleate; N-Methylaspartate; Neurons; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Time Factors; Valine | 2006 |
NMDA-induced preconditioning attenuates synaptic plasticity in the rat hippocampus.
Topics: Action Potentials; Adenosine A1 Receptor Antagonists; Animals; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; Hippocampus; In Vitro Techniques; Long-Term Potentiation; Male; N-Methylaspartate; Neural Inhibition; Neuronal Plasticity; Neurons; NG-Nitroarginine Methyl Ester; Rats; Rats, Sprague-Dawley; Valine; Xanthines | 2006 |
cAMP-dependent protein kinase postsynaptic localization regulated by NMDA receptor activation through translocation of an A-kinase anchoring protein scaffold protein.
Topics: A Kinase Anchor Proteins; Adaptor Proteins, Signal Transducing; Age Factors; Analysis of Variance; Animals; Animals, Newborn; Bacterial Proteins; Blotting, Western; Calcineurin; Cells, Cultured; Cyclic AMP-Dependent Protein Kinases; Cytoplasm; Dendrites; Disks Large Homolog 4 Protein; Drug Interactions; Enzyme Activation; Excitatory Amino Acid Agonists; Gene Expression Regulation; Hippocampus; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; Long-Term Synaptic Depression; Luminescent Proteins; Male; Membrane Proteins; Mutagenesis; N-Methylaspartate; Neurons; Phosphorylation; Protein Transport; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Serine; Synapses; Time Factors; Transfection; Valine | 2006 |
Developmental changes in NMDA neurotoxicity reflect developmental changes in subunit composition of NMDA receptors.
Topics: Age Factors; Animals; Biomarkers; Calpain; Dipeptides; Disks Large Homolog 4 Protein; Dizocilpine Maleate; Enzyme Activation; Excitatory Amino Acid Antagonists; Fluorescent Dyes; Gene Expression Regulation, Developmental; Glucose; Hippocampus; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; L-Lactate Dehydrogenase; Membrane Proteins; N-Methylaspartate; Neurons; Oxygen; Phenols; Piperidines; Propidium; Protein Subunits; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Spectrin; Valine | 2006 |
Alteration in sensitivity of ionotropic glutamate receptors and tachykinin receptors in spinal cord contribute to development and maintenance of nerve injury-evoked neuropathic pain.
Topics: Alanine; Analgesics; Animals; Behavior, Animal; Benzamides; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Indoles; Isoindoles; Male; N-Methylaspartate; Pain; Pain Measurement; Piperidines; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Kainic Acid; Receptors, Tachykinin; Sciatic Nerve; Spinal Cord; Substance P; Valine | 2006 |
Homeostatic plasticity during alcohol exposure promotes enlargement of dendritic spines.
Topics: Actins; Animals; Animals, Newborn; Cell Survival; Central Nervous System Depressants; Dendritic Spines; Disks Large Homolog 4 Protein; Drug Interactions; Ethanol; Excitatory Amino Acid Agonists; Gene Expression Regulation; Hippocrateaceae; Homeostasis; Hypoglycemic Agents; Intracellular Signaling Peptides and Proteins; Membrane Proteins; Microscopy, Confocal; N-Methylaspartate; Neurons; Palmitates; Rats; Synapsins; Valine | 2006 |
Presynaptic modulation by somatostatin in the neostriatum.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Corpus Striatum; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Inhibitory Postsynaptic Potentials; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Presynaptic Terminals; Rats; Rats, Wistar; Somatostatin; Valine | 2008 |
The role of NMDA receptors in regulating group II metabotropic glutamate receptor-mediated long-term depression in rat medial prefrontal cortex.
Topics: Amino Acids; Animals; Animals, Newborn; Bridged Bicyclo Compounds, Heterocyclic; Cyclopropanes; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; In Vitro Techniques; Long-Term Synaptic Depression; Male; N-Methylaspartate; Patch-Clamp Techniques; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Valine | 2008 |
High potassium induces taurine release by osmosensitive and osmoresistant mechanisms in the rat hippocampus in vivo.
Topics: Analysis of Variance; Animals; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Extracellular Space; Hippocampus; Hypertonic Solutions; Male; Microdialysis; N-Methylaspartate; Potassium Chloride; Rats; Rats, Sprague-Dawley; Taurine; Valine; Water-Electrolyte Balance | 2009 |
Pregnenolone sulfate induces NMDA receptor dependent release of dopamine from synaptic terminals in the striatum.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Corpus Striatum; Dopamine; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Male; Microscopy, Electron, Scanning; N-Methylaspartate; Potassium Chloride; Pregnenolone; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Synaptosomes; Tritium; Valine | 2008 |
Developmental switch in requirement for PKA RIIbeta in NMDA-receptor-dependent synaptic plasticity at Schaffer collateral to CA1 pyramidal cell synapses.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Analysis of Variance; Animals; Animals, Newborn; Biophysics; Cyclic AMP-Dependent Protein Kinase RIIbeta Subunit; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Hippocampus; In Vitro Techniques; Mice; Mice, Knockout; N-Methylaspartate; Neural Pathways; Neuronal Plasticity; Pyramidal Cells; Receptors, N-Methyl-D-Aspartate; Synapses; Time Factors; Valine | 2009 |
Alternating low frequency stimulation of medial septal and commissural fibers induces NMDA-dependent, long-lasting potentiation of hippocampal synapses in urethane-anesthetized rats.
Topics: Anesthetics, Intravenous; Animals; Dizocilpine Maleate; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Hippocampus; Male; Mecamylamine; Muscarinic Antagonists; N-Methylaspartate; Nicotinic Antagonists; Rats; Rats, Long-Evans; Scopolamine; Septum of Brain; Synapses; Urethane; Valine | 2009 |
Homeostatic presynaptic suppression of neuronal network bursts.
Topics: Action Potentials; Anesthetics, Local; Animals; Calcium; Cells, Cultured; Dose-Response Relationship, Drug; Electric Stimulation; Embryo, Mammalian; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Extracellular Fluid; Green Fluorescent Proteins; Hippocampus; Inhibitory Postsynaptic Potentials; Lidocaine; N-Methylaspartate; Nerve Net; Neurons; Presynaptic Terminals; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Synaptosomal-Associated Protein 25; Tetrodotoxin; Time Factors; Transfection; Valine; Vesicle-Associated Membrane Protein 2 | 2009 |
HPLC determination of acidic D-amino acids and their N-methyl derivatives in biological tissues.
Topics: Aniline Compounds; Chromatography, High Pressure Liquid; D-Aspartic Acid; Glutamates; Isomerism; N-Methylaspartate; Sensitivity and Specificity; Time Factors; Valine | 2009 |
Synaptic and extrasynaptic factors governing glutamatergic retinal waves.
Topics: Amino Acid Transport Systems, Acidic; Animals; Animals, Newborn; Aspartic Acid; Calcium; Dihydro-beta-Erythroidine; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; GABA Antagonists; Glutamic Acid; In Vitro Techniques; Mice; Mice, Inbred C57BL; Mice, Knockout; Models, Biological; N-Methylaspartate; Neural Inhibition; Nicotinic Antagonists; Patch-Clamp Techniques; Pyridazines; Quinoxalines; Retinal Ganglion Cells; Synapses; Synaptic Transmission; Time Factors; Valine; Vesicular Glutamate Transport Protein 1 | 2009 |
Growth factor-dependent trafficking of cerebellar NMDA receptors via protein kinase B/Akt phosphorylation of NR2C.
Topics: 14-3-3 Proteins; Alanine; Animals; Biotinylation; Cell Line, Transformed; Cells, Cultured; Cerebellum; Dendrites; Excitatory Amino Acid Antagonists; Gene Expression; Green Fluorescent Proteins; Hippocampus; Humans; Immunoprecipitation; In Vitro Techniques; Insulin-Like Growth Factor I; Luminescent Proteins; Mice; Mutation; N-Methylaspartate; Neurons; Oncogene Protein v-akt; Phosphorylation; Protein Structure, Tertiary; Protein Transport; Proto-Oncogene Proteins c-akt; Rats; Receptors, N-Methyl-D-Aspartate; Serine; Signal Transduction; Transfection; Valine | 2009 |
Selective vulnerability of hippocampal cornu ammonis 1 pyramidal cells to excitotoxic insult is associated with the expression of polyamine-sensitive N-methyl-D-asparate-type glutamate receptors.
Topics: Animals; CA1 Region, Hippocampal; CA3 Region, Hippocampal; Dentate Gyrus; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Female; Hippocampus; In Vitro Techniques; Male; N-Methylaspartate; Nerve Degeneration; Neuroprotective Agents; Neurotoxins; Piperidines; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Spermidine; Valine | 2010 |
Bidirectional synaptic plasticity in response to single or paired pulse activation of NMDA receptors.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Biophysics; Dose-Response Relationship, Drug; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Hippocampus; In Vitro Techniques; N-Methylaspartate; Neuronal Plasticity; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Valine | 2010 |
Xenon inhibits excitatory but not inhibitory transmission in rat spinal cord dorsal horn neurons.
Topics: Animals; Excitatory Postsynaptic Potentials; Inhibitory Postsynaptic Potentials; Male; N-Methylaspartate; Patch-Clamp Techniques; Posterior Horn Cells; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Tetrodotoxin; Valine; Xenon | 2010 |
The lateral paragigantocellular nucleus modulates parasympathetic cardiac neurons: a mechanism for rapid eye movement sleep-dependent changes in heart rate.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Biophysics; Electric Stimulation; Excitatory Amino Acid Antagonists; GABA Antagonists; Heart; Heart Rate; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Medulla Oblongata; N-Methylaspartate; Neurons; Nicotine; Nicotinic Agonists; Patch-Clamp Techniques; Pyridazines; Rats; Rats, Sprague-Dawley; Sleep, REM; Time Factors; Vagus Nerve; Valine | 2010 |
Adrenergic receptor-mediated disinhibition of mitral cells triggers long-term enhancement of synchronized oscillations in the olfactory bulb.
Topics: Action Potentials; Adrenergic alpha-Agonists; Animals; Animals, Newborn; Bicuculline; Biological Clocks; Biophysical Phenomena; Electric Stimulation; Excitatory Amino Acid Antagonists; GABA Antagonists; GABA-A Receptor Antagonists; In Vitro Techniques; Inhibitory Postsynaptic Potentials; N-Methylaspartate; Neurons; Norepinephrine; Olfactory Bulb; Pyridazines; Quinoxalines; Rats; Receptors, Adrenergic; Valine | 2010 |
Developmental maturation of excitation and inhibition balance in principal neurons across four layers of somatosensory cortex.
Topics: Animals; Cerebral Cortex; Excitatory Postsynaptic Potentials; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Mice; Mice, Transgenic; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Time Factors; Valine | 2011 |
Activity-dependent ubiquitination of GluA1 mediates a distinct AMPA receptor endocytosis and sorting pathway.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analysis of Variance; Animals; Animals, Newborn; Cells, Cultured; Endocytosis; Endosomal Sorting Complexes Required for Transport; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Green Fluorescent Proteins; Hippocampus; Humans; Immunoprecipitation; Membrane Potentials; Microscopy, Confocal; N-Methylaspartate; Nedd4 Ubiquitin Protein Ligases; Neurons; Organ Culture Techniques; Patch-Clamp Techniques; Protein Transport; Rats; Receptors, AMPA; RNA Interference; Transfection; Ubiquitin-Protein Ligases; Ubiquitination; Valine | 2010 |
Frequency-dependent recruitment of fast amino acid and slow neuropeptide neurotransmitter release controls gonadotropin-releasing hormone neuron excitability.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Anterior Thalamic Nuclei; Biophysics; Electric Stimulation; Excitatory Amino Acid Antagonists; Female; gamma-Aminobutyric Acid; Glutamic Acid; Gonadotropin-Releasing Hormone; Green Fluorescent Proteins; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; N-Methylaspartate; Neurons; Neuropeptides; Neurotransmitter Agents; Patch-Clamp Techniques; Reaction Time; Receptors, G-Protein-Coupled; Receptors, Kisspeptin-1; Statistics, Nonparametric; Synaptic Transmission; Valine | 2011 |
Glucosensing by GnRH neurons: inhibition by androgens and involvement of AMP-activated protein kinase.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Brain; Dihydrotestosterone; Enzyme Activation; Estrogens; Female; GABA Antagonists; Glucose; Gonadotropin-Releasing Hormone; In Vitro Techniques; Membrane Potentials; Mice; Mice, Transgenic; N-Methylaspartate; Neurons; Ovariectomy; Ribonucleotides; Valine | 2011 |
Astrocytic activation of A1 receptors regulates the surface expression of NMDA receptors through a Src kinase dependent pathway.
Topics: Adenosine A1 Receptor Antagonists; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analysis of Variance; Animals; Astrocytes; Biotinylation; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Gene Expression Regulation; Immunoprecipitation; In Vitro Techniques; Mice; Mice, Inbred C57BL; Mice, Transgenic; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Phosphorylation; Receptor, Adenosine A1; Receptors, N-Methyl-D-Aspartate; Signal Transduction; SNARE Proteins; Somatosensory Cortex; src-Family Kinases; Tyrosine; Valine | 2011 |
Cerebroside-A provides potent neuroprotection after cerebral ischaemia through reducing glutamate release and Ca²⁺ influx of NMDA receptors.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Analysis of Variance; Animals; Brain Ischemia; Calcium; Cerebral Infarction; Cerebrosides; Charybdotoxin; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glucose; Glutamic Acid; Hippocampus; Hypoxia; In Vitro Techniques; Infarction, Middle Cerebral Artery; Long-Term Potentiation; Male; Mice; Mice, Inbred C57BL; N-Methylaspartate; Neuroprotective Agents; Neurotoxins; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Tetrazolium Salts; Valine | 2012 |
Sex difference in stress-induced enhancement of hippocampal CA1 long-term depression during puberty.
Topics: Adrenalectomy; Androgens; Animals; Animals, Newborn; Aspartic Acid; CA1 Region, Hippocampal; Corticosterone; Dexamethasone; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Glucocorticoids; Glutamic Acid; In Vitro Techniques; Long-Term Synaptic Depression; Male; Methoxyhydroxyphenylglycol; N-Methylaspartate; Neurons; Ovariectomy; Rats; Rats, Sprague-Dawley; Rats, Wistar; Sex Characteristics; Statistics, Nonparametric; Stress, Psychological; Synaptosomes; Testosterone; Valine | 2012 |
Pull-push neuromodulation of LTP and LTD enables bidirectional experience-induced synaptic scaling in visual cortex.
Topics: Adrenergic Agonists; Adrenergic Antagonists; Analysis of Variance; Animals; Animals, Newborn; Biophysics; Drug Administration Schedule; Drug Interactions; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Isoproterenol; Long-Term Potentiation; Long-Term Synaptic Depression; Methoxamine; Mice; Mice, Inbred C57BL; Mice, Knockout; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Photic Stimulation; Propranolol; Rats; Rats, Long-Evans; Receptors, AMPA; Synapses; Valine; Visual Cortex; Visual Pathways | 2012 |
Endogenous ACh effects on NMDA-induced interictal-like discharges along the septotemporal hippocampal axis of adult rats and their modulation by an early life generalized seizure.
Topics: Acetylcholine; Analysis of Variance; Animals; Atropine; Cholinesterase Inhibitors; Convulsants; Disease Models, Animal; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Hippocampus; In Vitro Techniques; Male; Muscarinic Antagonists; N-Methylaspartate; Neurons; Pentylenetetrazole; Physostigmine; Rats; Rats, Sprague-Dawley; Seizures; Sex Factors; Valine | 2012 |
Presynaptic NMDA receptor-mediated modulation of excitatory neurotransmission in the mouse dorsal motor nucleus of the vagus.
Topics: Animals; Biophysics; Chlorides; Electric Stimulation; Excitatory Amino Acid Agents; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; Glutamates; In Vitro Techniques; Male; Medulla Oblongata; Mice; Motor Neurons; N-Methylaspartate; Patch-Clamp Techniques; Picrotoxin; Presynaptic Terminals; Receptors, N-Methyl-D-Aspartate; Sodium Channel Blockers; Tetrodotoxin; Vagus Nerve; Valine; Zinc Compounds | 2012 |
Activity-dependent cleavage of the K-Cl cotransporter KCC2 mediated by calcium-activated protease calpain.
Topics: Action Potentials; Analysis of Variance; Animals; Animals, Newborn; Calcium; Calcium Ionophores; Calpain; Cycloheximide; Cysteine Proteinase Inhibitors; Dipeptides; Dizocilpine Maleate; Dose-Response Relationship, Drug; Emetine; Excitatory Amino Acid Antagonists; Gene Expression Regulation; Hippocampus; In Vitro Techniques; Ionomycin; K Cl- Cotransporters; Leupeptins; Magnesium; Male; Membrane Potentials; N-Methylaspartate; Patch-Clamp Techniques; Protein Synthesis Inhibitors; Pyramidal Cells; Rats; Rats, Wistar; Statistics, Nonparametric; Symporters; Valine | 2012 |
Arf6-GEF BRAG1 regulates JNK-mediated synaptic removal of GluA1-containing AMPA receptors: a new mechanism for nonsyndromic X-linked mental disorder.
Topics: ADP-Ribosylation Factor 6; ADP-Ribosylation Factors; Amino Acid Motifs; Animals; Animals, Newborn; CA1 Region, Hippocampal; Calcium; Calmodulin; Chelating Agents; Disks Large Homolog 4 Protein; Egtazic Acid; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; HeLa Cells; Humans; Intracellular Signaling Peptides and Proteins; Ionomycin; Luminescent Proteins; Male; MAP Kinase Signaling System; Membrane Glycoproteins; Membrane Potentials; Membrane Proteins; Mutation; N-Methylaspartate; Neurons; Organ Culture Techniques; Patch-Clamp Techniques; Presynaptic Terminals; Protein Binding; Protein Conformation; Rats; Receptors, AMPA; Sulfotransferases; Transfection; Valine | 2012 |
Astrocyte-derived thrombospondins mediate the development of hippocampal presynaptic plasticity in vitro.
Topics: Adenosine; Amines; Animals; Animals, Newborn; Astrocytes; Biophysics; Coculture Techniques; CREB-Binding Protein; Culture Media, Conditioned; Cyclic AMP; Cyclohexanecarboxylic Acids; Dynamin I; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Female; Gabapentin; gamma-Aminobutyric Acid; Hippocampus; Male; N-Methylaspartate; Nerve Tissue Proteins; Neuronal Plasticity; Organ Culture Techniques; Patch-Clamp Techniques; Phosphorylation; Potassium Chloride; Presynaptic Terminals; Protein Kinase Inhibitors; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Statistics, Nonparametric; Synapses; Thionucleotides; Thrombospondins; Valine; Vesicular Glutamate Transport Protein 1 | 2012 |
A mechanistic study on urine retention in d-amphetamine addicts.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Afferent Pathways; Amidines; Amphetamine-Related Disorders; Animals; Benzophenanthridines; Central Nervous System Stimulants; Chronic Disease; Colforsin; Dextroamphetamine; Excitatory Amino Acid Agonists; Female; Glutamic Acid; Isoquinolines; N-Methylaspartate; Oxidants; Protein Kinase Inhibitors; Rats, Wistar; Reflex; Spinal Cord; Sulfonamides; Urinary Retention; Urination; Valine | 2014 |
N-methyl-D-aspartate receptor agonism and antagonism within the amygdaloid central nucleus suppresses pain affect: differential contribution of the ventrolateral periaqueductal gray.
Topics: Animals; Central Amygdaloid Nucleus; Dose-Response Relationship, Drug; Electroshock; Male; N-Methylaspartate; Narcotic Antagonists; Pain; Pain Perception; Peptide Fragments; Periaqueductal Gray; Proto-Oncogene Proteins c-fos; Random Allocation; Rats, Long-Evans; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid, mu; Reflex; Somatostatin; Valine; Vocalization, Animal | 2014 |
Participation of NMDA receptors in the lateral hypothalamus in gastric erosion induced by cold-water restraint.
Topics: Analysis of Variance; Animals; Cold Temperature; Disease Models, Animal; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Hypothalamic Area, Lateral; Male; N-Methylaspartate; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Restraint, Physical; Stomach Ulcer; Valine | 2015 |
Stimulation of glutamate receptors in the ventral tegmental area is necessary for serotonin-2 receptor-induced increases in mesocortical dopamine release.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Amphetamines; Animals; Dopamine; Excitatory Amino Acid Antagonists; Glutamic Acid; Male; Microdialysis; N-Methylaspartate; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, Serotonin, 5-HT2; Serotonin 5-HT2 Receptor Agonists; Valine; Ventral Tegmental Area | 2015 |
Extracellular ATP modulates synaptic plasticity induced by activation of metabotropic glutamate receptors in the hippocampus.
Topics: Adenosine Triphosphate; Animals; CA1 Region, Hippocampal; Dioxolanes; Excitatory Postsynaptic Potentials; Gene Expression Regulation; Guinea Pigs; Long-Term Potentiation; Long-Term Synaptic Depression; Male; Microtomy; N-Methylaspartate; Neurons; Purines; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Synapses; Tissue Culture Techniques; Valine | 2015 |
Alteration of the Centromedial Amygdala Glutamatergic Synapses by the BDNF Val66Met Polymorphism.
Topics: Animals; Brain-Derived Neurotrophic Factor; Central Amygdaloid Nucleus; Conditioning, Classical; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Extinction, Psychological; Fear; Glutamic Acid; In Vitro Techniques; Male; Methionine; Mice; Mice, Inbred C57BL; Mice, Transgenic; N-Methylaspartate; Neurons; Piperidines; Polymorphism, Single Nucleotide; Synapses; Valine | 2015 |
A corticothalamic switch: controlling the thalamus with dynamic synapses.
Topics: Animals; Bacterial Proteins; Central Nervous System Stimulants; Channelrhodopsins; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; gamma-Aminobutyric Acid; In Vitro Techniques; Luminescent Proteins; Mice; Mice, Inbred ICR; Mice, Transgenic; N-Methylaspartate; Neural Pathways; Optogenetics; Picrotoxin; Receptors, Neurotensin; Somatosensory Cortex; Synapses; Thalamus; Valine | 2015 |
Distinct effects of ventral tegmental area NMDA and acetylcholine receptor blockade on conditioned reinforcement produced by food-associated cues.
Topics: Animals; Conditioning, Classical; Conditioning, Operant; Cues; Dopamine; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Male; Mecamylamine; N-Methylaspartate; Nicotinic Antagonists; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Receptors, Nicotinic; Reinforcement, Psychology; Scopolamine; Valine; Ventral Tegmental Area | 2015 |
Contribution of the basolateral amygdala NMDA and muscarinic receptors in rat's memory retrieval.
Topics: Animals; Basolateral Nuclear Complex; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Male; Mental Recall; Muscarinic Antagonists; N-Methylaspartate; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Scopolamine; Valine | 2017 |
Nanoscale Molecular Reorganization of the Inhibitory Postsynaptic Density Is a Determinant of GABAergic Synaptic Potentiation.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Algorithms; Animals; Carrier Proteins; Cells, Cultured; Computer Simulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; GABAergic Neurons; Hippocampus; Long-Term Synaptic Depression; Male; Membrane Proteins; Mice; Mice, Inbred C57BL; Models, Neurological; N-Methylaspartate; Peptides; Polymers; Post-Synaptic Density; Receptors, GABA-A; Valine | 2017 |
Ketamine upregulates eNOS expression in human astroglial A172 cells: Possible role in its antidepressive properties.
Topics: Astrocytes; Cell Line, Transformed; Dose-Response Relationship, Drug; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glioblastoma; Humans; Immunosuppressive Agents; Ketamine; MAP Kinase Signaling System; N-Methylaspartate; Nitric Oxide Synthase Type III; RNA, Messenger; Sirolimus; Time Factors; Up-Regulation; Valine | 2017 |
Astrocytes modulate thalamic sensory processing via mGlu2 receptor activation.
Topics: Animals; Animals, Newborn; Astrocytes; Calcium; Citrates; Dose-Response Relationship, Drug; Enzyme Inhibitors; Excitatory Amino Acid Agents; In Vitro Techniques; Iontophoresis; Male; N-Methylaspartate; Rats; Rats, Sprague-Dawley; Sensory Receptor Cells; Sodium Channel Blockers; Tetrodotoxin; Thalamus; Valine; Vibrissae | 2017 |
NMDARs contribute to the facial stimuli-evoked mossy fiber-granule cell synaptic transmission in vivo in mice.
Topics: Animals; Cerebellar Cortex; Excitatory Amino Acid Antagonists; Mice; Mice, Inbred ICR; N-Methylaspartate; Neurons; Physical Stimulation; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission; Valine; Vibrissae | 2020 |