n-methylaspartate has been researched along with u-50488 in 10 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 7 (70.00) | 18.2507 |
| 2000's | 3 (30.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jacocks, HM; McMahon, PN; Werling, LL | 1 |
| Althaus, JS; Hudson, CJ; Means, ED; Scherch, HM; Von Voigtlander, PF | 1 |
| Benicourt, C; Junien, JL; Lockhart, BP; Privat, A; Soulard, P | 1 |
| Desban, M; Gauchy, C; Glowinski, J; Kemel, ML; Krebs, MO | 1 |
| Ferkany, J; Kolesnikov, YA; Pasternak, GW | 1 |
| Gu, Y; Huang, LY; Lai, SL | 1 |
| Long, LO; Mokha, SS; Wang, XM; Zhang, KM | 1 |
| Tao, PL; Wu, CC; Wu, SC; Yang, CH | 1 |
| Nardo, L; Soong, Y; Szeto, HH; Walker, D; Wu, D; Young, IR | 1 |
| Baker, AK; Hoffmann, VL; Meert, TF | 1 |
10 other study(ies) available for n-methylaspartate and u-50488
| Article | Year |
|---|---|
Regulation of [3H]dopamine release from guinea pig striatum by NMDA receptor/channel activators and inhibitors.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Corpus Striatum; Dopamine; Glycine; Guinea Pigs; Ion Channels; Magnesium; Male; N-Methylaspartate; Piperazines; Pyrrolidines; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid | 1990 |
The kappa opioid-related anticonvulsants U-50488H and U-54494A attenuate N-methyl-D-aspartate induced brain injury in the neonatal rat.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Animals, Newborn; Brain; Brain Diseases; Diuresis; Dose-Response Relationship, Drug; N-Methylaspartate; Organ Size; Pyrrolidines; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, kappa; Staining and Labeling | 1991 |
Distinct neuroprotective profiles for sigma ligands against N-methyl-D-aspartate (NMDA), and hypoxia-mediated neurotoxicity in neuronal culture toxicity studies.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Anti-Arrhythmia Agents; Antihypertensive Agents; Benzofurans; Brain Ischemia; Cell Death; Cells, Cultured; Dizocilpine Maleate; Hypoxia; Kainic Acid; Ligands; N-Methylaspartate; Neurons; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa; Receptors, Phencyclidine; Receptors, sigma | 1995 |
Role of dynorphin and GABA in the inhibitory regulation of NMDA-induced dopamine release in striosome- and matrix-enriched areas of the rat striatum.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Bicuculline; Corpus Striatum; Dopamine; Dynorphins; gamma-Aminobutyric Acid; Kinetics; Male; N-Methylaspartate; Naloxone; Neurons; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa; Receptors, Opioid, mu; Tetrodotoxin; Tritium | 1994 |
Blockade of mu and kappa 1 opioid analgesic tolerance by NPC17742, a novel NMDA antagonist.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Amino Acids; Analgesics; Animals; Drug Tolerance; Mice; Mice, Inbred Strains; Morphine; N-Methylaspartate; Pyrrolidines; Receptors, Opioid, kappa; Receptors, Opioid, mu | 1993 |
Dynorphin uses a non-opioid mechanism to potentiate N-methyl-D-aspartate currents in single rat periaqueductal gray neurons.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Action Potentials; Analgesics, Non-Narcotic; Animals; Drug Synergism; Dynorphins; N-Methylaspartate; Naloxone; Naltrexone; Narcotic Antagonists; Neurons; Patch-Clamp Techniques; Peptide Fragments; Periaqueductal Gray; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid, kappa | 1998 |
Orphanin FQ (nociceptin) modulates responses of trigeminal neurons evoked by excitatory amino acids and somatosensory stimuli, and blocks the substance P-induced facilitation of N-methyl-D-aspartate-evoked responses.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Excitatory Amino Acid Agonists; Excitatory Amino Acids; Injections, Intraventricular; Iontophoresis; Male; Medulla Oblongata; N-Methylaspartate; Naloxone; Narcotic Antagonists; Neurons; Nociceptin; Opioid Peptides; Physical Stimulation; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Somatosensory Cortex; Substance P; Trigeminal Nerve | 1999 |
Study the mechanisms of U-50,488 to prevent the development of morphine tolerance in guinea pigs.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics, Non-Narcotic; Animals; Drug Tolerance; Excitatory Amino Acid Agonists; Glutamic Acid; Guinea Pigs; In Vitro Techniques; Male; Morphine; N-Methylaspartate; Narcotics; Nitric Oxide; Pain Threshold; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Tritium | 2000 |
Site and mechanism of action of dynorphin A-(1-13) and N-methyl-D-aspartate on ACTH release in fetal sheep.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Adrenocorticotropic Hormone; Animals; Cyclooxygenase Inhibitors; Dynorphins; Female; Fetus; Hypothalamus; Indomethacin; N-Methylaspartate; Peptide Fragments; Pituitary Gland; Placenta; Pregnancy; Receptors, Opioid, kappa; Sheep | 2002 |
Interactions of NMDA antagonists and an alpha 2 agonist with mu, delta and kappa opioids in an acute nociception assay.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Adrenergic alpha-Agonists; Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Benzamides; Clonidine; Dextromethorphan; Dose-Response Relationship, Drug; Drug Synergism; Fentanyl; Ketamine; Male; Mice; Morphine; N-Methylaspartate; Pain; Pain Measurement; Piperazines; Reaction Time; Receptors, Opioid | 2002 |