n-methylaspartate has been researched along with thiophenes in 8 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 7 (87.50) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (12.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Corbett, R; Cornfeldt, ML; Dunn, RW; Fielding, S; Laws-Ricker, L; Martin, LL; Payack, JF; Rush, DK; Wilmot, CA | 1 |
| Echevarria, E; Hughes, J; Hunter, JC; Robles, L; Tortella, FC | 1 |
| Chernack, J; Cornfeldt, ML; Fielding, S; Martin, LL; Payack, JF; Ramirez, V; Rudolphi, KA; Rush, DK; Wilker, JC; Wilmot, CA | 1 |
| Elben, U; Grome, JJ; Lee, GE; Lee, TB; Martin, LL; Paulus, E; Porsche-Wiebking, E; Rudolphi, KA; Rush, DK; Wilmot, CA | 1 |
| Katsuta, K; Kinoshita, T; Kuno, A; Nakanishi, H; Ohkubo, M; Shirakawa, K; Takasugi, H; Ueda, Y | 1 |
| Battaglia, G; Bruno, V; Catania, MV; Di Grezia, R; Kingston, A; Nicoletti, F; O'Neill, MJ | 1 |
| Battaglia, G; Bond, A; Bruno, V; Clark, BP; Harris, JR; Kingston, AE; Lodge, D; Monn, JA; Nicoletti, F; O'Neill, MJ; Schoepp, DD | 1 |
| Chiarugi, A; Formentini, L; Gerace, E; Landucci, E; Moroni, F; Pellegrini-Giampietro, DE; Scartabelli, T | 1 |
8 other study(ies) available for n-methylaspartate and thiophenes
| Article | Year |
|---|---|
Preclinical anxiolytic profiles of 7189 and 8319, novel non-competitive NMDA antagonists.
Topics: Aniline Compounds; Animals; Anti-Anxiety Agents; Anticonvulsants; Behavior, Animal; Binding, Competitive; Diazepam; Dizocilpine Maleate; Dose-Response Relationship, Drug; Learning; Male; Mice; N-Methylaspartate; Piperazines; Rats; Rats, Inbred Strains; Seizures; Thiophenes; Tritium; Yohimbine | 1990 |
PD117302, a selective non-peptide opioid kappa agonist, protects against NMDA and maximal electroshock convulsions in rats.
Topics: Animals; Anticonvulsants; Aspartic Acid; Dose-Response Relationship, Drug; Electroshock; Flurothyl; Male; N-Methylaspartate; Pyrroles; Random Allocation; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, kappa; Thiophenes; Time Factors | 1990 |
Preclinical anticonvulsant and neuroprotective profile of 8319, a non-competitive NMDA antagonist.
Topics: Aniline Compounds; Animals; Anticonvulsants; Binding, Competitive; Brain Diseases; Brain Ischemia; Dizocilpine Maleate; Gerbillinae; Hippocampus; Male; Mice; Mice, Inbred Strains; N-Methylaspartate; Rats; Rats, Inbred Strains; Thiophenes; Tritium | 1990 |
Synthesis, resolution, and SAR of (+/-)-2-amino-N-methyl-alpha-(3-methyl-2-thienyl)benzeneethanamine++ + and related analogs as noncompetitive NMDA antagonists with neuroprotective properties.
Topics: Aniline Compounds; Animals; Anti-Anxiety Agents; Anticonvulsants; Binding, Competitive; Brain Ischemia; Cerebral Infarction; Crystallography, X-Ray; Disease Models, Animal; Gerbillinae; Hippocampus; Isomerism; Male; Mice; Molecular Structure; N-Methylaspartate; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Structure-Activity Relationship; Thiophenes | 1994 |
Studies on cerebral protective agents. X. Synthesis and evaluation of anticonvulsant activities for novel 4,5,6,7-tetrahydrothieno[3,3-c]pyridines and related compounds.
Topics: Animals; Anticonvulsants; Convulsants; Excitatory Amino Acid Agonists; Hypoxia; Injections, Intraventricular; Male; Mice; Mice, Inbred ICR; N-Methylaspartate; Pyridines; Stereoisomerism; Structure-Activity Relationship; Thiophenes; X-Ray Diffraction | 1996 |
Neuroprotective activity of the potent and selective mGlu1a metabotropic glutamate receptor antagonist, (+)-2-methyl-4 carboxyphenylglycine (LY367385): comparison with LY357366, a broader spectrum antagonist with equal affinity for mGlu1a and mGlu5 recept
Topics: Animals; Astrocytes; Benzoates; Caudate Nucleus; Cells, Cultured; Cerebral Cortex; Excitatory Amino Acid Antagonists; Fetus; Gerbillinae; Glycine; Ischemic Attack, Transient; Male; Mice; N-Methylaspartate; Necrosis; Neurons; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Thiophenes | 1999 |
Neuroprotective actions of novel and potent ligands of group I and group II metabotropic glutamate receptors.
Topics: Animals; Benzoates; Bridged Bicyclo Compounds; Cells, Cultured; Cerebral Cortex; Drug Evaluation, Preclinical; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Gerbillinae; Glycine; Ischemia; Male; N-Methylaspartate; Nerve Degeneration; Neurons; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Thiophenes | 1999 |
Mild activation of poly(ADP-ribose) polymerase (PARP) is neuroprotective in rat hippocampal slice models of ischemic tolerance.
Topics: Amino Acid Chloromethyl Ketones; Animals; Caspase 3; Caspase 7; Caspase Inhibitors; Cell Death; Cell Hypoxia; Cells, Cultured; Glucose; Glycine; Hippocampus; Ischemic Preconditioning; Isoquinolines; MAP Kinase Signaling System; N-Methylaspartate; Neurons; Neuroprotective Agents; Phenanthrenes; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Rats; Rats, Wistar; Resorcinols; Thiophenes | 2012 |