n-methylaspartate has been researched along with sirolimus in 13 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (7.69) | 18.2507 |
| 2000's | 2 (15.38) | 29.6817 |
| 2010's | 9 (69.23) | 24.3611 |
| 2020's | 1 (7.69) | 2.80 |
| Authors | Studies |
|---|---|
| Dawson, TM; Dawson, VL; Dinerman, JL; Snyder, SH; Steiner, JP; Uhl, GR | 1 |
| Kawamata, T; Nakai, M; Tanaka, C; Taniguchi, T; Terashima, A; Yasuda, M | 1 |
| Font-Nieves, M; Martín, ME; Petegnief, V; Planas, AM; Salinas, M | 1 |
| Benavides, AD; Caccamo, A; Javors, MA; Kraig, E; Majumder, S; Medina, DX; Oddo, S; Richardson, A; Strong, R | 1 |
| Bettio, LE; Budni, J; Colla, AR; Cunha, MP; Oliveira, Á; Pazini, FL; Rodrigues, AL | 1 |
| Ichikawa, A; Ishii, K; Kurauchi, Y; Mori, A; Nakahara, T; Sakamoto, K | 1 |
| Aoki, Y; Asano, D; Ishii, K; Mori, A; Nakahara, T; Sakamoto, K; Ushikubo, H | 1 |
| Aoki, Y; Asano, D; Hayashi, I; Ishii, K; Mori, A; Nakahara, T; Sakamoto, K; Ushikubo, H | 2 |
| Bishop, WA; Fischer, AJ; Goodman, ZA; Palazzo, I; Todd, L; Volkov, L; Zelinka, CP | 1 |
| Ashkenazi, S; Berent, E; Weizman, A; Yuhas, Y | 1 |
| Meng, Y; Ren, WH; Shi, XY; Wan, L; Wang, J; Yang, G; Zou, LP | 1 |
| Kim, EJ; Kim, MJ; Lee, M; Yum, MS | 1 |
13 other study(ies) available for n-methylaspartate and sirolimus
| Article | Year |
|---|---|
Immunosuppressant FK506 enhances phosphorylation of nitric oxide synthase and protects against glutamate neurotoxicity.
Topics: Amino Acid Oxidoreductases; Animals; Cell Death; Cells, Cultured; Cerebral Cortex; Excitatory Amino Acid Antagonists; Fetus; Glutamates; Glutamic Acid; Immunosuppressive Agents; N-Methylaspartate; Neurons; Neurotoxins; Nitric Oxide Synthase; Phosphorylation; Polyenes; Rats; Rats, Sprague-Dawley; Sirolimus; Tacrolimus | 1993 |
Rapamycin and FK506 induce long-term potentiation by pairing stimulation via an intracellular Ca(2+) signaling mechanism in rat hippocampal CA1 neurons.
Topics: Animals; Calcium; Calcium Signaling; Chelating Agents; Dose-Response Relationship, Drug; Drug Interactions; Egtazic Acid; Electric Stimulation; Excitatory Postsynaptic Potentials; Hippocampus; Immunophilins; Long-Term Potentiation; Male; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Rats; Rats, Wistar; Sirolimus; Tacrolimus; Tacrolimus Binding Proteins; Time Factors | 2000 |
Nitric oxide mediates NMDA-induced persistent inhibition of protein synthesis through dephosphorylation of eukaryotic initiation factor 4E-binding protein 1 and eukaryotic initiation factor 4G proteolysis.
Topics: Adaptor Proteins, Signal Transducing; Animals; Carrier Proteins; Cell Cycle Proteins; Cell Survival; Cells, Cultured; Coculture Techniques; Cytoprotection; Eukaryotic Initiation Factor-4G; Eukaryotic Initiation Factors; Intracellular Signaling Peptides and Proteins; N-Methylaspartate; Neurons; Nitric Oxide; Nitric Oxide Synthase; Phosphoproteins; Phosphorylation; Protein Binding; Protein Biosynthesis; Rats; Rats, Sprague-Dawley; Sirolimus | 2008 |
Lifelong rapamycin administration ameliorates age-dependent cognitive deficits by reducing IL-1β and enhancing NMDA signaling.
Topics: Aging; Animals; Drosophila melanogaster; Interleukin-1beta; Learning; Memory Disorders; Mice; N-Methylaspartate; Signal Transduction; Sirolimus; TOR Serine-Threonine Kinases | 2012 |
Guanosine produces an antidepressant-like effect through the modulation of NMDA receptors, nitric oxide-cGMP and PI3K/mTOR pathways.
Topics: Analysis of Variance; Animals; Antidepressive Agents; Arginine; Cyclic GMP; Depression; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Excitatory Amino Acid Agents; Exploratory Behavior; Female; Freezing Reaction, Cataleptic; Guanosine; Hindlimb Suspension; Immunosuppressive Agents; Male; Mice; N-Methylaspartate; Nitric Oxide; Phosphatidylinositol 3-Kinases; Receptors, N-Methyl-D-Aspartate; Serine; Signal Transduction; Sirolimus; Swimming; TOR Serine-Threonine Kinases | 2012 |
Rapamycin prevents N-methyl-D-aspartate-induced retinal damage through an ERK-dependent mechanism in rats.
Topics: Animals; Extracellular Signal-Regulated MAP Kinases; Immunohistochemistry; In Situ Nick-End Labeling; Male; N-Methylaspartate; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Retina; Sirolimus | 2014 |
Preventive effects of rapamycin on inflammation and capillary degeneration in a rat model of NMDA-induced retinal injury.
Topics: Animals; Anti-Inflammatory Agents; Capillaries; Male; N-Methylaspartate; Rats, Sprague-Dawley; Retinal Diseases; Sirolimus | 2015 |
Protective Effects of Everolimus against N-Methyl-D-aspartic Acid-Induced Retinal Damage in Rats.
Topics: Animals; Disease Models, Animal; Everolimus; Extracellular Signal-Regulated MAP Kinases; In Situ Nick-End Labeling; Inflammation; Intravitreal Injections; Leukocyte Common Antigens; Male; N-Methylaspartate; Neuroprotective Agents; Phosphorylation; Protein Kinase Inhibitors; Rats, Sprague-Dawley; Retina; Retinal Diseases; Retinal Ganglion Cells; Sirolimus; TOR Serine-Threonine Kinases | 2015 |
mTor signaling is required for the formation of proliferating Müller glia-derived progenitor cells in the chick retina.
Topics: Animals; Cell Movement; Cell Nucleus; Cell Proliferation; Chickens; Ependymoglial Cells; Fibroblast Growth Factor 2; Insulin; Insulin-Like Growth Factor I; Insulin-Like Growth Factor II; MAP Kinase Signaling System; Models, Biological; N-Methylaspartate; Neuroglia; PAX6 Transcription Factor; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; Retina; Signal Transduction; Sirolimus; Stem Cells; TOR Serine-Threonine Kinases | 2016 |
Protective effects of PF-4708671 against N-methyl-d-aspartic acid-induced retinal damage in rats.
Topics: Animals; Calcium-Binding Proteins; Imidazoles; Kidney Diseases; Leukocyte Common Antigens; Leukocytes; Male; Microfilament Proteins; Microglia; N-Methylaspartate; Neuroprotective Agents; Phosphorylation; Piperazines; Protein Kinase Inhibitors; Rats; Rats, Sprague-Dawley; Ribosomal Protein S6 Kinases; Sirolimus | 2016 |
Ketamine upregulates eNOS expression in human astroglial A172 cells: Possible role in its antidepressive properties.
Topics: Astrocytes; Cell Line, Transformed; Dose-Response Relationship, Drug; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glioblastoma; Humans; Immunosuppressive Agents; Ketamine; MAP Kinase Signaling System; N-Methylaspartate; Nitric Oxide Synthase Type III; RNA, Messenger; Sirolimus; Time Factors; Up-Regulation; Valine | 2017 |
Regulatory role of hippocampal PI3K and mTOR signaling pathway in NMDA-induced infant spasm rats.
Topics: Animals; Cell Death; Disease Models, Animal; Female; Hippocampus; N-Methylaspartate; Phosphatidylinositol 3-Kinase; Phosphorylation; Protein Kinase Inhibitors; Rats, Sprague-Dawley; Signal Transduction; Sirolimus; Spasm; TOR Serine-Threonine Kinases; Wortmannin | 2019 |
Rapamycin Cannot Reduce Seizure Susceptibility in Infantile Rats with Malformations of Cortical Development Lacking mTORC1 Activation.
Topics: Animals; Female; Malformations of Cortical Development; Mechanistic Target of Rapamycin Complex 1; N-Methylaspartate; Pregnancy; Rats; Seizures; Sirolimus; Spasm; TOR Serine-Threonine Kinases | 2022 |