Page last updated: 2024-08-22

n-methylaspartate and propofol

n-methylaspartate has been researched along with propofol in 19 studies

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (26.32)18.2507
2000's9 (47.37)29.6817
2010's3 (15.79)24.3611
2020's2 (10.53)2.80

Authors

AuthorsStudies
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Albert, A; Bonhomme, V; Collette, J; Hans, P; Moonen, G1
Ahmad, I; Pleuvry, BJ1
Bertlik, M; MacDonald, JF; Orser, BA; Wang, LY1
Cottrell, JE; Kass, IS; Zhu, H1
Kitamura, R; Miyawaki, I; Mori, K; Nakamura, K; Yokubol, B1
Inoue, T; Mashimo, T; Shibuta, S; Shimizu, T; Sriranganathan, V; Tomi, K1
Dohi, S; Iida, H; Nagase, K; Ohata, H1
Gillessen, T; Grasshoff, C2
Duan, SM; Xu, AJ; Zeng, YM1
Eriksson, P; Fredriksson, A; Gordh, T; Pontén, E1
Baxter, MG; Crosby, G; Culley, DJ; Murphy, KL1
Chan, HH; Ng, YF; To, CH; Yap, MK1
Meenakshisundaram, R; Senthilkumaran, S; Sweni, S; Thirumalaikolundusubramanian, P1
Azma, T; Hama-Tomioka, K; Hatakeyama, N; Kawahito, S; Kinoshita, H; Kondo, T; Matsuda, N; Nakahata, K1
Corsini, S; Ghezzi, F; Monni, L; Nistri, A1
Chen, J; Hu, B; Shen, M; Wang, F; Yang, Y; Zhou, Q; Zou, X1
Aglio, LS; Akeju, O; Balanza, GA; Brown, EN; Cash, SS; Cosgrove, GR; Eskandar, EN; Lewis, LD; Paulk, AC; Peled, N; Peterfreund, RA; Purdon, PL; Richardson, RM; Santa Cruz Mercado, LA; Soper, D; Tian, F; Williams, ZM; Zelmann, R; Zhou, DW1

Trials

2 trial(s) available for n-methylaspartate and propofol

ArticleYear
Ketamine, not propofol, attenuates cerebrovascular response to carbon dioxide in humans with isoflurane anesthesia.
    Journal of clinical anesthesia, 2001, Volume: 13, Issue:8

    Topics: Adult; Anesthesia, Inhalation; Anesthetics, Inhalation; Anesthetics, Intravenous; Blood Flow Velocity; Blood Pressure; Carbon Dioxide; Cerebrovascular Circulation; Female; Heart Rate; Humans; Isoflurane; Ketamine; Male; Middle Cerebral Artery; N-Methylaspartate; Propofol

2001
Effect of different doses of esketamine compared with fentanyl combined with propofol on hypotension in patients undergoing painless abortion surgery: a prospective, randomized, double-blind controlled clinical trial.
    BMC anesthesiology, 2022, 09-28, Volume: 22, Issue:1

    Topics: Analgesics; Anesthetics, Intravenous; Double-Blind Method; Female; Fentanyl; Humans; Hypotension; Ketamine; N-Methylaspartate; Pregnancy; Propofol; Prospective Studies; Receptors, N-Methyl-D-Aspartate

2022

Other Studies

17 other study(ies) available for n-methylaspartate and propofol

ArticleYear
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Propofol protects cultured rat hippocampal neurons against N-methyl-D-aspartate receptor-mediated glutamate toxicity.
    Journal of neurosurgical anesthesiology, 1994, Volume: 6, Issue:4

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain Ischemia; Cells, Cultured; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Fetus; Glutamic Acid; Hippocampus; Kainic Acid; N-Methylaspartate; Nerve Degeneration; Neurons; Phosphopyruvate Hydratase; Propofol; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Time Factors

1994
Interactions between opioid drugs and propofol in laboratory models of seizures.
    British journal of anaesthesia, 1995, Volume: 74, Issue:3

    Topics: Analgesics, Opioid; Animals; Bicuculline; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Female; Fentanyl; Kainic Acid; Meperidine; Mice; Mice, Inbred Strains; Morphine; N-Methylaspartate; Propofol; Seizures

1995
Inhibition by propofol (2,6 di-isopropylphenol) of the N-methyl-D-aspartate subtype of glutamate receptor in cultured hippocampal neurones.
    British journal of pharmacology, 1995, Volume: 116, Issue:2

    Topics: Animals; Cells, Cultured; Dose-Response Relationship, Drug; Drug Interactions; Hippocampus; Kainic Acid; Mice; Mice, Inbred Strains; N-Methylaspartate; Patch-Clamp Techniques; Propofol; Receptors, N-Methyl-D-Aspartate

1995
The effect of thiopental and propofol on NMDA- and AMPA-mediated glutamate excitotoxicity.
    Anesthesiology, 1997, Volume: 87, Issue:4

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Anesthetics, Intravenous; Animals; Dimethyl Sulfoxide; Excitatory Amino Acid Agonists; Glutamic Acid; Hippocampus; In Vitro Techniques; Male; N-Methylaspartate; Propofol; Rats; Rats, Sprague-Dawley; Thiopental

1997
Suppression of cyclic guanosine monophosphate formation in rat cerebellar slices by propofol, ketamine and midazolam.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1997, Volume: 44, Issue:12

    Topics: Anesthetics, Intravenous; Animals; Cerebellum; Cyclic GMP; Depression, Chemical; Glutamic Acid; In Vitro Techniques; Ketamine; Midazolam; N-Methylaspartate; Nitroprusside; Propofol; Rats; Rats, Wistar; Vasodilator Agents

1997
The effects of propofol on NMDA- or nitric oxide-mediated neurotoxicity in vitro.
    Neuroreport, 2001, Feb-12, Volume: 12, Issue:2

    Topics: Animals; Cell Survival; Cells, Cultured; Cerebral Cortex; Excitatory Amino Acid Agonists; Female; Fetus; Free Radical Scavengers; In Vitro Techniques; N-Methylaspartate; Neurons; Nitric Oxide; Nitric Oxide Donors; Pregnancy; Propofol; Rats; Rats, Wistar; Triazenes

2001
The effect of propofol on increased superoxide concentration in cultured rat cerebrocortical neurons after stimulation of N-methyl-d-aspartate receptors.
    Anesthesia and analgesia, 2002, Volume: 95, Issue:4

    Topics: Anesthetics, Intravenous; Animals; Cells, Cultured; Cerebral Cortex; Excitatory Amino Acid Agonists; Fluorescent Dyes; Free Radical Scavengers; N-Methylaspartate; Neurons; Phenanthridines; Propofol; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Superoxides

2002
Effects of intrathecal NMDA and AMPA receptors agonists or antagonists on antinociception of propofol.
    Acta pharmacologica Sinica, 2004, Volume: 25, Issue:1

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analgesics; Animals; Dizocilpine Maleate; Female; Injections, Spinal; Male; Mice; N-Methylaspartate; Nociceptors; Pain Threshold; Propofol; Quinoxalines; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate

2004
Effects of propofol on N-methyl-D-aspartate receptor-mediated calcium increase in cultured rat cerebrocortical neurons.
    European journal of anaesthesiology, 2005, Volume: 22, Issue:6

    Topics: Anesthetics, Intravenous; Animals; Calcium; Cells, Cultured; Cerebral Cortex; Cytosol; Excitatory Amino Acid Agonists; Female; Fluorescent Dyes; Microscopy, Confocal; N-Methylaspartate; Neurons; Organic Chemicals; Pregnancy; Propofol; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate

2005
Neonatal exposure to a combination of N-methyl-D-aspartate and gamma-aminobutyric acid type A receptor anesthetic agents potentiates apoptotic neurodegeneration and persistent behavioral deficits.
    Anesthesiology, 2007, Volume: 107, Issue:3

    Topics: Analgesics; Anesthetics, Combined; Anesthetics, Intravenous; Animals; Animals, Newborn; Anti-Anxiety Agents; Apoptosis; Behavior, Animal; Brain; Diazepam; Disease Models, Animal; Drug Combinations; Drug Synergism; Excitatory Amino Acid Agonists; GABA Antagonists; Ketamine; Male; Maze Learning; Mice; N-Methylaspartate; Neurodegenerative Diseases; Propofol; Receptors, GABA-A; Sodium Chloride; Thiopental; Time Factors

2007
Different behavioral effects of neurotoxic dorsal hippocampal lesions placed under either isoflurane or propofol anesthesia.
    Hippocampus, 2008, Volume: 18, Issue:3

    Topics: Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Behavior, Animal; Denervation; Hippocampus; Isoflurane; Learning; Learning Disabilities; Male; Memory; Memory Disorders; N-Methylaspartate; Nerve Degeneration; Neurotoxins; Propofol; Rats; Rats, Inbred F344

2008
The characteristics of multifocal electroretinogram in isolated perfused porcine eye: cellular contributions to the in vitro porcine mfERG.
    Documenta ophthalmologica. Advances in ophthalmology, 2008, Volume: 117, Issue:3

    Topics: Aminobutyrates; Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Electroretinography; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Isoflurane; N-Methylaspartate; Pipecolic Acids; Propofol; Retina; Sodium Channel Blockers; Swine; Tetrodotoxin

2008
Propofol's derivative: a potential drug for erectile dysfunction?
    Medical hypotheses, 2011, Volume: 77, Issue:4

    Topics: Anesthetics, Intravenous; Animals; Calcium; Dopamine; Erectile Dysfunction; gamma-Aminobutyric Acid; Male; N-Methylaspartate; Nitric Oxide; Potassium Channels; Propofol; Prostaglandins; Rats; Receptors, Dopamine D2

2011
Roles of neuronal nitric oxide synthase, oxidative stress, and propofol in N-methyl-D-aspartate-induced dilatation of cerebral arterioles.
    British journal of anaesthesia, 2012, Volume: 108, Issue:1

    Topics: Anesthetics, Intravenous; Animals; Arterioles; Cerebrovascular Circulation; Dinoprost; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Fluorescent Antibody Technique; Image Processing, Computer-Assisted; In Vitro Techniques; Male; Microscopy, Video; N-Methylaspartate; NADPH Oxidases; Nitric Oxide; Nitric Oxide Synthase Type I; Oxidative Stress; Propofol; Rats; Rats, Wistar; Superoxides; Vasodilation

2012
Neurotoxicity of propofol on rat hypoglossal motoneurons in vitro.
    Neuroscience letters, 2017, Aug-10, Volume: 655

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Anesthetics, Intravenous; Animals; Animals, Newborn; Apoptosis Inducing Factor; Cell Count; gamma-Aminobutyric Acid; Glycine; Hypoglossal Nerve; In Vitro Techniques; Motor Neurons; N-Methylaspartate; Patch-Clamp Techniques; Propofol; Rats, Wistar

2017
Characterizing brain dynamics during ketamine-induced dissociation and subsequent interactions with propofol using human intracranial neurophysiology.
    Nature communications, 2023, 03-29, Volume: 14, Issue:1

    Topics: Antidepressive Agents; Cerebral Cortex; Humans; Ketamine; N-Methylaspartate; Neurophysiology; Propofol; Receptors, N-Methyl-D-Aspartate

2023