Page last updated: 2024-08-22

n-methylaspartate and pentylenetetrazole

n-methylaspartate has been researched along with pentylenetetrazole in 84 studies

Research

Studies (84)

Timeframe	Studies, this research(%)	All Research%
pre-1990	8 (9.52)	18.7374
1990's	36 (42.86)	18.2507
2000's	20 (23.81)	29.6817
2010's	14 (16.67)	24.3611
2020's	6 (7.14)	2.80

Authors

Authors	Studies
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J	1
Serratosa, J; Trullas, R; Tusell, JM; Vendrell, M	1
Hume, DA; Le, F; Shanley, BC; Wilce, PA	1
Conti, L; Ellenberger, SR; Ellenberger, WP; Ferkany, JW; Guzewska, ME; Hudkins, R; Kyle, DJ; Narayanan, BA; Patch, R; Rzeszotarski, WJ	1
Berrino, L; Leyva, J; Maione, S; Rossi, F; Vitagliano, S	1
Pleuvry, BJ; Wildin, JD	1
Beal, MF; MacGarvey, U; Miller, J; Vécsei, L	1
Garyaev, AP; Piotrovsky, LB; Poznyakova, LN	1
Oles, RJ; Singh, L; Tricklebank, MD	1
Himori, N; Martin, JR; Moreau, JL	1
Igarashi, H; Kamei, J; Kasuya, Y	1
De Barry, J; Mathis, C; Ungerer, A	1
Oles, R; Singh, L; Woodruff, G	1
Dolin, SJ; Halsey, MJ; Hunter, AB; Little, HJ	1
Curran, T; Hempstead, J; Macgregor-Leon, PF; Mitchelmore, C; Morgan, JI; Sonnenberg, JL	1
Calder, LD; Karler, R; Murphy, V; Turkanis, SA	1
Jackson, BW; Lewin, AH; Marvizón, JC; Monn, JA; Rice, KC; Skolnick, P	1
McCaslin, PP; Morgan, WW	1
Hutchison, AJ; Lehmann, J; McPherson, SE; Mondadori, C; Murphy, DE; Schmutz, M; Sinton, CM; Steel, DJ; Tsai, C; Williams, M	1
Hönack, D; Löscher, W; Nolting, B	1
Balm, M; Coyle, JT; Markl, A; Zaczek, R	1
Klitgaard, H; Laudrup, P	1
Ferrer, I; Planas, AM; Rodríguez Farré, E; Soriano, MA	1
Rauca, C; Rüthrich, HL	1
Carter, MF; Deutsch, SI; Jacobson, KA; Lin, RC; Mastropaolo, J; Meshulam, Y; Von Lubitz, DK	1
Ahmad, I; Lauretti, GR; Pleuvry, BJ	1
Cannizzaro, C; Cannizzaro, G; Flugy, A; Gagliand, M; Mineo, A; Sabatino, M	1
Adachi, I; Eigyo, M; Inoue, Y; Ishibashi, C; Koyabu, K; Matsushita, A; Murata, S; Sakaguchi, I; Shiomi, T; Ueda, M	1
Hornsperger, JM; Knoedgen, B; Sablone, M; Sarhan, S; Seiler, N	1
Belknap, JK; Crabbe, JC; Merrill, CM	1
Abila, B; Davies, JA; Richens, A	1
Bartsch, R; Engel, J; Hönack, D; Kutscher, B; Löscher, W; Polymeropoulos, EE; Rostock, A; Rundfeldt, C; Tober, C; White, HS; Wolf, HH	1
Camón, L; de Vera, N; Giménez-Llort, L; Martínez, E	1
Baran, L; Przegaliñski, E; Siwanowicz, J	1
Hu, PS; Ross, SB	1
Andersen, PH; Burns, CM; Chang, H; Crider, AM; el-Assadi, AA; Hinko, CN; Ho, B; Kliem, MA; Klitgaard, H; Seo, TH; Steinmiller, CL; Tietz, EI; Venkatarangan, P	1
Nance, DM; Wilkinson, M; Wintrip, N	1
Bashkatova, VG; Mikoian, VD; Narkevich, VB; Raevskiĭ, KS; Vanin, AF; Vitskova, GIu	2
Lapin, IP; Mirzaev, SM; Oxenkrug, GF; Ryzov, IV	1
Balestra, M; Borrelli, AR; Cramer, CL; Eismann, MS; Freedman, LR; Hudzik, TJ; Knowles, MK; Mahmood, N; McCarthy, DJ; Murray, RJ; Palmer, GC; Stagnitto, ML	1
Brum, LF; Elisabetsky, E; Souza, DO	1
Juhng, KN; Kirkby, RD; Kokate, TG; Llamas, J; Rogawski, MA; Yamaguchi, S	1
Kim, DC; Todd, MM	1
Abe, K; Nakanishi, K; Saito, H	1
Bijak, M; Chojnacka-Wójcik, E; Czuczwar, SJ; Kroczka, B; Kłodzińska, A; Pilc, A; Swiader, M	1
Bac, P; Delcourt, P; Herrenknecht, C; Maurois, P; Stables, JP; Vamecq, J	1
Atapour, N; Kalantaripour, TP; Niazi, M; Nourpanah, M	1
Bopelet, M; Bum, EN; Herrling, P; Jeker, A; Meyer, C; Olpe, HR; Portet, C; Rakotonirina, A; Rakotonirina, SV; Schmutz, M	1
Alvarado, R; Camacho-Arroyo, I; Manjarrez, J	1
Gustaw, K; Rubaj, A; Sieklucka-Dziuba, M; Zgodzinski, W	1
Amabeoku, GJ; Bienvenu, E; Eagles, PK; Scott, G; Springfield, EP	1
Sasaki-Adams, DM; Stafstrom, CE	1
Bale, AS; Balster, RL; Wiley, JL	1
Liu, KL; Liu, YQ; Ruan, JX; Wang, YA; Zheng, JQ; Zhou, WX	1
Li, JX; Liu, KL; Liu, YQ; Ruan, JX; Wang, YA; Yue, YJ; Zheng, JQ; Zhou, WX	1
Amabeoku, GJ; Green, I; Kabatende, J	1
Choi, D; Harris, RH; Kohn, H; Kupferberg, HJ; Stables, JP; Stöhr, T; Walton, N; White, HS	1
Becker, HC; Carpenter-Hyland, EP; Chandler, LJ; Hearing, MC; Mulholland, PJ; Woodward, JJ	1
Itoh, K; Watanabe, M	1
Bailabar, T; Bum, EN; Hiana, IR; Moto, FC; Nkainsa, LA; Rakotonirina, A; Rakotonirina, SV; Seke Etet, PF; Seyni, P; Taiwe, GS	1
Amabeoku, G	1
Moto, FC; Ngo Bum, E; Ngoupaye, GT; Nkantchoua, GC; Pelanken, MM; Rakotonirina, A; Rakotonirina, SV; Taiwe, GS	1
Godlevskii, LS; Kobolev, EV; Kresyun, VI	1
Baldwin, RA; Jäger, AK; Niquet, J; Pedersen, ME; Stafford, GI; van Staden, J; Wasterlain, CG	1
Aizenman, CD; Bell, MR; Deeg, KE; Lee, RH; Marsh-Armstrong, N; Mills, EA; Ruthazer, ES; Schwartz, N	1
Ekimova, IV; Feĭzulaev, BA; Guzhova, IV; Nitsinskaia, LE; Pastukhov, IuF	1
Bansod, K; Bhutada, P; Dixit, P; Mundhada, D; Mundhada, Y; Umathe, S	1
Ekimova, IV; Guzhova, IV; Margulis, BA; Nitsinskaya, LE; Pastukhov, YF; Romanova, IV	1
Beleboni, RO; Cunha, AO; dos Santos, WF; Fachim, HA; Faggion, SA; Gavin, AS; Pereira, AM	1
Benavidez, JM; Blednov, YA; Harris, RA; Homanics, GE	1
Mikroulis, AV; Psarropoulou, C	1
Aiello, R; Camastra, C; Chimirri, S; Citraro, R; De Sarro, G; Donato, G; Mainardi, P; Perucca, E; Russo, E; Scicchitano, F	1
da Silva Junior, PI; dos Santos, WF; Godoy, LD; Liberato, JL	1
Gmiro, VE; Serdyuk, SE; Veselkina, OS	1
Dehpour, AR; Heidary, MR; Javadi-Paydar, M; Jazaeri, F; Rahimi, N; Sadeghzadeh, M	1
Cruz, SL; Gauthereau-Torres, MY; Rivera-García, MT	1
Ergina, JL; Kalemenev, SV; Postnikova, TY; Trofimova, AM; Zaitsev, AV; Zubareva, OE	1
Aghaei, I; Bahremand, T; Dehpour, AR; Ejtemaei-Mehr, S; Rahimi, N; Shafaroodi, H; Shayan, M; Zamanian, G	1
Kishore, DV; Prasad, NBL; Shylaja, H; Venkataranganna, MV; Viswanatha, GL	1
Abdollahi, A; Alotaibi, G; Dehpour, AR; Ghazi-Khansari, M; Imran Khan, M; Mumtaz, F; Rashki, A; Shadboorestan, A	1
Hložek, T; Kubová, H; Mareš, P; Páleníček, T; Uttl, L	1
Amini-Khoei, H; Boroujeni, SN; Lorigooini, Z; Rahimi-Madiseh, M; Taji, M	1
Amanlou, A; Dehpour, AR; Dejban, P; Eslami, F; Rahimi, N; Shayan, M	1

Other Studies

84 other study(ies) available for n-methylaspartate and pentylenetetrazole

Article	Year
Chemical genetics reveals a complex functional ground state of neural stem cells. Nature chemical biology, 2007, Volume: 3, Issue:5 Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells	2007
Lindane-induced convulsions in NMRI and OF1 mice: antagonism with (+)MK-801 and voltage-dependent calcium channel blockers. Brain research, 1992, Oct-16, Volume: 593, Issue:2 Topics: Animals; Anticonvulsants; Calcium Channel Blockers; Convulsants; Dizocilpine Maleate; Dose-Response Relationship, Drug; Hexachlorocyclohexane; Male; Mice; Mice, Inbred Strains; N-Methylaspartate; Nifedipine; Pentylenetetrazole; Picrotoxin; Seizures; Sesterterpenes; Species Specificity	1992
Involvement of gamma-aminobutyric acid and N-methyl-D-aspartate receptors in the inhibitory effect of ethanol on pentylenetetrazole-induced c-fos expression in rat brain. Journal of neurochemistry, 1992, Volume: 59, Issue:4 Topics: Animals; Azides; Benzodiazepines; Brain; Ethanol; Male; N-Methylaspartate; Pentylenetetrazole; Picrotoxin; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; RNA, Messenger	1992
Pharmacological profile of novel cyclic analogs of 2-amino-7-phosphonoheptanoic acid. Epilepsy research. Supplement, 1992, Volume: 8 Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Brain; Dose-Response Relationship, Drug; Electroshock; Male; Mice; N-Methylaspartate; Pentylenetetrazole; Receptors, N-Methyl-D-Aspartate; Seizures; Structure-Activity Relationship	1992
Pregnenolone sulfate increases the convulsant potency of N-methyl-D-aspartate in mice. European journal of pharmacology, 1992, Sep-04, Volume: 219, Issue:3 Topics: Animals; Dose-Response Relationship, Drug; Drug Synergism; Injections, Intraperitoneal; Male; Mice; N-Methylaspartate; Pentylenetetrazole; Pregnenolone; Receptors, N-Methyl-D-Aspartate; Seizures	1992
Tolerance to the anticonvulsant effects of clobazam in mice. Neuropharmacology, 1992, Volume: 31, Issue:2 Topics: Acoustic Stimulation; Animals; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Benzodiazepinones; Clobazam; Dose-Response Relationship, Drug; Drug Tolerance; Epilepsy; Mice; Mice, Inbred Strains; N-Methylaspartate; Pentylenetetrazole; Seizures	1992
Kynurenine and probenecid inhibit pentylenetetrazol- and NMDLA-induced seizures and increase kynurenic acid concentrations in the brain. Brain research bulletin, 1992, Volume: 28, Issue:2 Topics: Analysis of Variance; Animals; Brain; Cerebral Cortex; Corpus Striatum; Diazepam; Dose-Response Relationship, Drug; Kynurenic Acid; Kynurenine; Male; Mice; N-Methylaspartate; Pentylenetetrazole; Probenecid; Seizures	1992
Dipeptides--analogues of N-acetylaspartylglutamate inhibit convulsive effects of excitatory amino acids in mice. Neuroscience letters, 1991, Apr-29, Volume: 125, Issue:2 Topics: Animals; Cerebral Ventricles; Dipeptides; Glutamates; Glutamic Acid; Injections, Intraventricular; Kainic Acid; Mice; Mice, Inbred Strains; N-Methylaspartate; Neurotoxins; Pentylenetetrazole; Seizures; Structure-Activity Relationship	1991
Modulation of seizure susceptibility in the mouse by the strychnine-insensitive glycine recognition site of the NMDA receptor/ion channel complex. British journal of pharmacology, 1990, Volume: 99, Issue:2 Topics: Acoustic Stimulation; Animals; Aspartic Acid; Diazepam; Injections, Intraventricular; Ion Channels; Kynurenic Acid; Male; Mice; Mice, Inbred DBA; N-Methylaspartate; Pentylenetetrazole; Piperazines; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Seizures; Serine; Strychnine	1990
Cerebral ischemia decreases the behavioral effects and mortality rate elicited by activation of NMDA receptors in mice. Neuropharmacology, 1991, Volume: 30, Issue:11 Topics: Animals; Behavior, Animal; Carbon Dioxide; Dizocilpine Maleate; Female; Hypoxia; Injections, Intraventricular; Ischemic Attack, Transient; Mice; Mice, Inbred Strains; N-Methylaspartate; Nerve Degeneration; Pentylenetetrazole; Receptors, N-Methyl-D-Aspartate; Survival Rate	1991
Modulation by serotonin of glutamate-induced lethality in mice. Research communications in chemical pathology and pharmacology, 1991, Volume: 74, Issue:2 Topics: 5-Hydroxytryptophan; 8-Hydroxy-2-(di-n-propylamino)tetralin; alpha-Methyltyrosine; Analysis of Variance; Animals; Brain; Fenclonine; Male; Methyltyrosines; Mice; N-Methylaspartate; Pentylenetetrazole; Picrotoxin; Piperazines; Reserpine; Serotonin; Sodium Glutamate; Strychnine; Tetrahydronaphthalenes; Tryptophan	1991
NMDA antagonist properties of gamma-L-glutamyl-L-aspartate demonstrated on chemically induced seizures in mice. European journal of pharmacology, 1990, Aug-21, Volume: 185, Issue:1 Topics: Animals; Anticonvulsants; Behavior, Animal; Dipeptides; Dose-Response Relationship, Drug; Injections, Intraventricular; Kainic Acid; Male; Mice; N-Methylaspartate; Pentylenetetrazole; Picrotoxin; Quisqualic Acid; Receptors, N-Methyl-D-Aspartate; Seizures	1990
In vivo interaction of a polyamine with the NMDA receptor. European journal of pharmacology, 1990, May-16, Volume: 180, Issue:2-3 Topics: Animals; Aspartic Acid; Dose-Response Relationship, Drug; Drug Synergism; Injections, Intraventricular; Injections, Subcutaneous; Male; Mice; N-Methylaspartate; Pentylenetetrazole; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Seizures; Spermidine	1990
Anticonvulsant profile of the dihydropyridine calcium channel antagonists, nitrendipine and nimodipine. European journal of pharmacology, 1988, Jul-26, Volume: 152, Issue:1-2 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Anticonvulsants; Aspartic Acid; Atmospheric Pressure; Calcium Channel Blockers; Electrophysiology; Male; N-Methylaspartate; Nimodipine; Nitrendipine; Pentylenetetrazole; Rats; Rats, Inbred Strains; Seizures; Strychnine	1988
Glutamate receptor agonists increase the expression of Fos, Fra, and AP-1 DNA binding activity in the mammalian brain. Journal of neuroscience research, 1989, Volume: 24, Issue:1 Topics: Animals; Anticonvulsants; Aspartic Acid; Binding, Competitive; Blotting, Northern; Convulsants; DNA-Binding Proteins; Electroshock; Gene Expression Regulation; Immunoblotting; Kainic Acid; Male; Mice; Mice, Inbred BALB C; N-Methylaspartate; Nucleic Acid Hybridization; Pentylenetetrazole; Picrotoxin; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Receptors, Glutamate; Receptors, Neurotransmitter; RNA, Messenger; Seizures; Transcription Factors	1989
Pentylenetetrazol kindling in mice. Neuropharmacology, 1989, Volume: 28, Issue:8 Topics: Animals; Anticonvulsants; Aspartic Acid; Brain; Cannabidiol; Electric Stimulation; Kindling, Neurologic; Male; Mice; N-Methylaspartate; Neurotransmitter Agents; Pentylenetetrazole; Picrotoxin	1989
Blockade of N-methyl-D-aspartate induced convulsions by 1-aminocyclopropanecarboxylates. Life sciences, 1989, Volume: 45, Issue:18 Topics: Amino Acids; Amino Acids, Cyclic; Animals; Anticonvulsants; Aspartic Acid; Bicuculline; Dose-Response Relationship, Drug; Electroshock; Male; Mice; N-Methylaspartate; Pentylenetetrazole; Rats; Rats, Inbred Strains; Strychnine; Synaptic Membranes	1989
Continuously infused 2-amino-7-phosphonoheptanoic acid antagonizes N-methyl-D-aspartate-induced elevations of cyclic GMP in vivo in multiple brain areas and chemically-induced seizure activity. Neuropharmacology, 1986, Volume: 25, Issue:8 Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Aspartic Acid; Barbiturates; Bicuculline; Brain; Brain Chemistry; Cyclic GMP; Female; Injections, Intraventricular; N-Methylaspartate; Pentylenetetrazole; Rats; Rats, Inbred Strains	1986
CGS 19755, a selective and competitive N-methyl-D-aspartate-type excitatory amino acid receptor antagonist. The Journal of pharmacology and experimental therapeutics, 1988, Volume: 246, Issue:1 Topics: Acetylcholine; Aconitine; Animals; Anticonvulsants; Aspartic Acid; Avoidance Learning; Binding, Competitive; Darkness; Glutamates; Glutamic Acid; Male; N-Methylaspartate; Pentylenetetrazole; Picrotoxin; Pipecolic Acids; Piperidines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Seizures; Structure-Activity Relationship; Tetrodotoxin	1988
Evaluation of CPP, a selective NMDA antagonist, in various rodent models of epilepsy. Comparison with other NMDA antagonists, and with diazepam and phenobarbital. European journal of pharmacology, 1988, Jul-26, Volume: 152, Issue:1-2 Topics: Amygdala; Animals; Anticonvulsants; Aspartic Acid; Diazepam; Electroshock; Epilepsy; Female; Gerbillinae; Kindling, Neurologic; Male; Mice; N-Methylaspartate; Pentylenetetrazole; Phenobarbital; Piperazines; Psychomotor Performance; Rats; Time Factors	1988
A simple method for quantitative electroencephalographic assessment of drugs with convulsant and anticonvulsant properties. Journal of neuroscience methods, 1986, Volume: 18, Issue:4 Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Aspartic Acid; Convulsants; Diazepam; Electroencephalography; Hippocampus; Injections; Kainic Acid; Male; N-Methylaspartate; Pentylenetetrazole; Rats; Rats, Inbred Strains; Seizures	1986
Metabotropic excitatory amino acid receptor agonists selectively potentiate behavioral effects induced by ionotropic excitatory amino acid receptor agonists in mice. European journal of pharmacology, 1993, Nov-30, Volume: 250, Issue:1 Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Behavior, Animal; Cycloleucine; Drug Synergism; Injections, Intraventricular; Kainic Acid; Male; Mice; N-Methylaspartate; Neurotoxins; Pentylenetetrazole; Receptors, Glutamate; Seizures	1993
Regional expression of inducible heat shock protein-70 mRNA in the rat brain following administration of convulsant drugs. Brain research. Molecular brain research, 1994, Volume: 27, Issue:1 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Brain Chemistry; Convulsants; Gene Expression Regulation; Hexachlorocyclohexane; HSP70 Heat-Shock Proteins; Kainic Acid; Male; N-Methylaspartate; Nerve Tissue Proteins; Organ Specificity; Pentylenetetrazole; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; RNA, Messenger	1994
Moderate hypoxia reduces pentylenetetrazol-induced seizures. Naunyn-Schmiedeberg's archives of pharmacology, 1995, Volume: 351, Issue:3 Topics: Animals; Dizocilpine Maleate; Excitatory Amino Acid Agents; Hypoxia; Male; Mice; Mice, Inbred Strains; N-Methylaspartate; Pentylenetetrazole; Receptors, Purinergic; Seizures; Time Factors; Xanthines	1995
The effects of adenosine A3 receptor stimulation on seizures in mice. European journal of pharmacology, 1995, Feb-24, Volume: 275, Issue:1 Topics: Adenosine; Animals; Clonidine; Drug Interactions; Electroshock; Injections, Intraperitoneal; Male; Mice; N-Methylaspartate; p-Methoxy-N-methylphenethylamine; Pentylenetetrazole; Purinergic P1 Receptor Agonists; Seizures	1995
The activity of opioid analgesics in seizure models utilizing N-methyl-DL-aspartic acid, kainic acid, bicuculline and pentylenetetrazole. Neuropharmacology, 1994, Volume: 33, Issue:2 Topics: Analgesics, Opioid; Animals; Anticonvulsants; Bicuculline; Convulsants; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Kainic Acid; Male; Mice; N-Methylaspartate; Naloxone; Pentylenetetrazole; Seizures	1994
NMDA-GABA interactions in an animal model of behaviour: a gating mechanism from motivation toward psychotic-like symptoms. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 1994, Volume: 4, Issue:2 Topics: Alprazolam; Animals; Behavior, Animal; Desipramine; Disease Models, Animal; Dizocilpine Maleate; gamma-Aminobutyric Acid; Kindling, Neurologic; Male; Motivation; Motor Activity; Muscimol; N-Methylaspartate; Pentylenetetrazole; Psychotic Disorders; Rats; Rats, Wistar; Swimming	1994
Pharmacological studies on a new dihydrothienopyridine calcium antagonist, S-312-d. 5th communication: anticonvulsant effects in mice. Japanese journal of pharmacology, 1994, Volume: 65, Issue:2 Topics: Administration, Oral; Animals; Anticonvulsants; Bemegride; Calcium Channel Blockers; Dihydropyridines; Disease Models, Animal; Electroshock; Female; Injections, Subcutaneous; Male; Mice; Mice, Inbred DBA; N-Methylaspartate; Pentylenetetrazole; Picrotoxin; Seizures	1994
Enhanced endogenous ornithine concentrations protect against tonic seizures and coma in acute ammonia intoxication. Pharmacology & toxicology, 1993, Volume: 72, Issue:2 Topics: 3-Mercaptopropionic Acid; Ammonia; Animals; Brain Chemistry; Coma; Dialysis; Dizocilpine Maleate; Electroshock; Epilepsy, Generalized; Female; Glutamate-Ammonia Ligase; Methionine Sulfoximine; Mice; N-Methylaspartate; Ornithine; Ornithine-Oxo-Acid Transaminase; Pentylenetetrazole; Postural Balance; Putrescine; Strychnine	1993
Effect of acute alcohol withdrawal on sensitivity to pro- and anticonvulsant treatments in WSP mice. Alcoholism, clinical and experimental research, 1993, Volume: 17, Issue:6 Topics: Alcohol Withdrawal Delirium; Animals; Anticonvulsants; Arousal; Convulsants; Diazepam; Dizocilpine Maleate; Dose-Response Relationship, Drug; Female; Handling, Psychological; Kainic Acid; Mice; Mice, Inbred Strains; N-Methylaspartate; Pentylenetetrazole; Receptors, N-Methyl-D-Aspartate; Seizures	1993
Anticonvulsant effects of extracts of the west African black pepper, Piper guineense. Journal of ethnopharmacology, 1993, Volume: 39, Issue:2 Topics: Acoustic Stimulation; Animals; Anticonvulsants; Ethanol; Male; Medicine, African Traditional; Mice; Mice, Inbred DBA; N-Methylaspartate; Pentylenetetrazole; Plant Extracts; Seizures; Spices; Water	1993
D-23129: a new anticonvulsant with a broad spectrum activity in animal models of epileptic seizures. Epilepsy research, 1996, Volume: 23, Issue:3 Topics: Administration, Oral; Animals; Anticonvulsants; Behavior, Animal; Bicuculline; Carbamates; Dyskinesia, Drug-Induced; Electroshock; Female; Injections, Intraperitoneal; Injections, Subcutaneous; Male; Mice; Mice, Inbred DBA; N-Methylaspartate; Pentylenetetrazole; Phenylenediamines; Postural Balance; Rats; Rats, Wistar; Seizures; Strychnine	1996
Concentration of putrescine in plasma, frontal cortex and hippocampus of rats after systemic administration of the convulsants N-methyl-D-aspartate, pentylentetrazol, picrotoxinine, lindane and 4-aminopyridine. Neuroscience letters, 1996, Oct-11, Volume: 217, Issue:1 Topics: Aminopyrine; Analysis of Variance; Animals; Convulsants; Drug Evaluation, Preclinical; Evaluation Studies as Topic; Excitatory Amino Acid Agonists; Frontal Lobe; Hexachlorocyclohexane; Hippocampus; Kainic Acid; Male; N-Methylaspartate; Pentylenetetrazole; Picrotoxin; Putrescine; Rats; Rats, Wistar; Sesterterpenes	1996
The role of nitric oxide in chemically- and electrically-induced seizures in mice. Neuroscience letters, 1996, Oct-18, Volume: 217, Issue:2-3 Topics: Animals; Convulsants; Electroshock; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Indazoles; Male; Mice; Muscarinic Agonists; N-Methylaspartate; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Pentylenetetrazole; Pilocarpine; Seizures	1996
NMDA receptor-mediated increase in cyclic GMP in the rat cerebellum in vivo is blocked by alaproclate and GEA-857. Pharmacology & toxicology, 1997, Volume: 80, Issue:2 Topics: 4-Aminopyridine; Alanine; Animals; Behavior, Animal; Cerebellum; Convulsants; Cyclic GMP; Drug Interactions; Harmaline; Male; N-Methylaspartate; Pentylenetetrazole; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Seizures; Selective Serotonin Reuptake Inhibitors; Valine	1997
Anticonvulsant activity of novel derivatives of 2- and 3-piperidinecarboxylic acid in mice and rats. Neuropharmacology, 1996, Volume: 35, Issue:12 Topics: 4-Aminopyridine; Amygdala; Animals; Anticonvulsants; Brain; Convulsants; Kindling, Neurologic; Male; Mice; Mice, Inbred Strains; Molecular Structure; N-Methylaspartate; Neurotoxins; Nipecotic Acids; Pentylenetetrazole; Pipecolic Acids; Proline; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Receptors, Phencyclidine; Seizures; Structure-Activity Relationship; Valproic Acid	1996
The effect of lactation on induced Fos-like immunoreactivity in the rat hypothalamic paraventricular nucleus. Brain research, 1997, Apr-18, Volume: 754, Issue:1-2 Topics: Adrenalectomy; Animals; Excitatory Amino Acid Agonists; Female; Lactation; N-Methylaspartate; Paraventricular Hypothalamic Nucleus; Pentylenetetrazole; Postpartum Period; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley	1997
[Possible role of nitric oxide in pathogenesis of model seizure of the different etiology]. Biulleten' eksperimental'noi biologii i meditsiny, 1998, Volume: 125, Issue:1 Topics: Animals; Brain; Convulsants; Electron Spin Resonance Spectroscopy; Electroshock; Excitatory Amino Acid Agonists; gamma-Aminobutyric Acid; Lipid Peroxidation; Male; N-Methylaspartate; Nitric Oxide; Pentylenetetrazole; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Seizures; Semicarbazides	1998
Anticonvulsant activity of melatonin against seizures induced by quinolinate, kainate, glutamate, NMDA, and pentylenetetrazole in mice. Journal of pineal research, 1998, Volume: 24, Issue:4 Topics: Animals; Anticonvulsants; Brain; Convulsants; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamates; Injections, Intraperitoneal; Injections, Intraventricular; Kainic Acid; Male; Melatonin; Mice; Mice, Inbred C57BL; Motor Activity; N-Methylaspartate; Pentylenetetrazole; Quinolinic Acid; Seizures	1998
[S]-AR-R 15896AR-A novel anticonvulsant: acute safety, pharmacokinetic and pharmacodynamic properties. The Journal of pharmacology and experimental therapeutics, 1999, Volume: 288, Issue:1 Topics: 4-Aminopyridine; Animals; Anticonvulsants; Bicuculline; Electric Stimulation; Kainic Acid; Male; Mice; N-Methylaspartate; Pentylenetetrazole; Picrotoxin; Pyridines; Rats; Rats, Sprague-Dawley; Seizures; Seizures, Febrile; Strychnine; Time Factors; Weaning	1999
[Nitric oxide in the rat cerebral cortex in seizure models: potential ways of pharmacological modulation]. Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova, 1998, Volume: 84, Issue:10 Topics: Animals; Anticonvulsants; Arginine; Convulsants; Dizocilpine Maleate; Electron Spin Resonance Spectroscopy; Electroshock; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Male; N-Methylaspartate; Nitric Oxide; Nitroarginine; Pentylenetetrazole; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Seizures; Semicarbazides	1998
Anticonvulsant properties of linalool in glutamate-related seizure models. Phytomedicine : international journal of phytotherapy and phytopharmacology, 1999, Volume: 6, Issue:2 Topics: Acyclic Monoterpenes; Animals; Anticonvulsants; Cerebral Cortex; Disease Models, Animal; Dizocilpine Maleate; Glutamic Acid; Kindling, Neurologic; Male; Monoterpenes; N-Methylaspartate; Pentylenetetrazole; Phenobarbital; Quinolinic Acid; Radioligand Assay; Rats; Rats, Wistar; Seizures; Terpenes	1999
Convulsant actions of the neurosteroid pregnenolone sulfate in mice. Brain research, 1999, Jun-12, Volume: 831, Issue:1-2 Topics: Animals; Convulsants; Disease Susceptibility; Drug Synergism; Injections, Intraventricular; Male; Mice; N-Methylaspartate; Pentylenetetrazole; Pregnenolone; Receptors, GABA-A; Seizures	1999
Forebrain ischemia: effect on pharmacologically induced seizure thresholds in the rat. Brain research, 1999, Jun-12, Volume: 831, Issue:1-2 Topics: Analysis of Variance; Animals; Brain Ischemia; Convulsants; Lidocaine; Male; N-Methylaspartate; Pentylenetetrazole; Picrotoxin; Prosencephalon; Rats; Rats, Sprague-Dawley; Seizures	1999
The anticonvulsive effect of glutathione in mice. Biological & pharmaceutical bulletin, 1999, Volume: 22, Issue:11 Topics: Animals; Anticonvulsants; Behavior, Animal; Glutathione; Injections, Intraventricular; Male; Mice; N-Methylaspartate; Oxidation-Reduction; Pentylenetetrazole; Seizures	1999
Roles of group II metabotropic glutamate receptors in modulation of seizure activity. Naunyn-Schmiedeberg's archives of pharmacology, 2000, Volume: 361, Issue:3 Topics: Analysis of Variance; Animals; Anti-Anxiety Agents; Brain; Bridged Bicyclo Compounds; Convulsants; Diazepam; Dose-Response Relationship, Drug; Drug Combinations; Electrophysiology; Male; Mice; N-Methylaspartate; Pentylenetetrazole; Picrotoxin; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Seizures	2000
Synthesis and anticonvulsant and neurotoxic properties of substituted N-phenyl derivatives of the phthalimide pharmacophore. Journal of medicinal chemistry, 2000, Apr-06, Volume: 43, Issue:7 Topics: Administration, Oral; Animals; Anticonvulsants; Batrachotoxins; Cerebral Cortex; Convulsants; Electroshock; Excitatory Amino Acid Agonists; gamma-Aminobutyric Acid; In Vitro Techniques; Ion Channel Gating; Kainic Acid; Magnesium Deficiency; Mice; N-Methylaspartate; Patch-Clamp Techniques; Pentylenetetrazole; Phenytoin; Phthalimides; Rats; Seizures; Sodium Channel Blockers; Structure-Activity Relationship; Synaptosomes; Tumor Cells, Cultured	2000
Chemical kindling and seizure susceptibility in morphine dependent rats. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2000, Volume: 10, Issue:6 Topics: Animals; Caffeine; Convulsants; Disease Models, Animal; Drug Interactions; Excitatory Amino Acid Agonists; GABA Antagonists; Kindling, Neurologic; Male; Morphine; Morphine Dependence; N-Methylaspartate; Pentylenetetrazole; Picrotoxin; Rats; Rats, Wistar; Receptors, GABA; Receptors, Purinergic P1; Seizures	2000
Anticonvulsant properties of the methanolic extract of Cyperus articulatus (Cyperaceae). Journal of ethnopharmacology, 2001, Volume: 76, Issue:2 Topics: Animals; Anticonvulsants; Behavior, Animal; Convulsants; Electroshock; Male; Medicine, Traditional; Mice; N-Methylaspartate; Pentylenetetrazole; Plant Extracts; Seizures	2001
Differential effects of NMDA antagonists microinjections into the nucleus reticularis pontis caudalis on seizures induced by pentylenetetrazol in the rat. Epilepsy research, 2001, Volume: 46, Issue:1 Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Dizocilpine Maleate; Electroencephalography; Excitatory Amino Acid Antagonists; Male; Microinjections; N-Methylaspartate; Pentylenetetrazole; Pons; Rats; Rats, Wistar; Reticular Formation; Seizures	2001
Nociceptin, OP4 receptor ligand in different models of experimental epilepsy. Peptides, 2002, Volume: 23, Issue:3 Topics: Animals; Bicuculline; Disease Models, Animal; Electric Stimulation; Epilepsy; Female; Mice; N-Methylaspartate; Nociceptin; Nociceptin Receptor; Opioid Peptides; Pentylenetetrazole; Receptors, Opioid	2002
Anticonvulsant activity of aqueous extract of Leonotis leonurus. Phytomedicine : international journal of phytotherapy and phytopharmacology, 2002, Volume: 9, Issue:3 Topics: Animals; Anticonvulsants; Bicuculline; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Lamiaceae; Male; Mice; N-Methylaspartate; Pentylenetetrazole; Phytotherapy; Picrotoxin; Plant Extracts; Seizures	2002
NMDA-induced seizures in developing rats cause long-term learning impairment and increased seizure susceptibility. Epilepsy research, 2003, Volume: 53, Issue:1-2 Topics: Animals; Animals, Newborn; Brain; Cognition Disorders; Convulsants; Electroencephalography; Excitatory Amino Acid Agonists; Learning Disabilities; Maze Learning; N-Methylaspartate; Neurons; Pentylenetetrazole; Phenotype; Rats; Rats, Sprague-Dawley; Seizures; Status Epilepticus	2003
Evaluation of toluene dependence and cross-sensitization to diazepam. Life sciences, 2003, May-16, Volume: 72, Issue:26 Topics: Animals; Convulsants; Diazepam; Excitatory Amino Acid Agonists; Inhalation Exposure; Male; Mice; Motor Activity; N-Methylaspartate; Pentylenetetrazole; Seizures; Solvents; Substance-Related Disorders; Toluene	2003
[Anticonvulsant effect of phencynonate hydrochloride on maximal electroshock seizure and the metrazol seizure threshold test in mice]. Yao xue xue bao = Acta pharmaceutica Sinica, 2005, Volume: 40, Issue:6 Topics: Animals; Animals, Newborn; Anticonvulsants; Aza Compounds; Cells, Cultured; Electroshock; Female; Glycolates; Hippocampus; Lethal Dose 50; Male; Mice; N-Methylaspartate; Neurons; Neuroprotective Agents; Pentylenetetrazole; Rats; Rats, Wistar; Seizures	2005
Anticonvulsant effects of phencynonate hydrochloride and other anticholinergic drugs in soman poisoning: neurochemical mechanisms. Life sciences, 2005, Nov-26, Volume: 78, Issue:2 Topics: Animals; Anticonvulsants; Aza Compounds; Behavior, Animal; Brain Chemistry; Cells, Cultured; Cholinergic Antagonists; Cholinesterase Inhibitors; Convulsants; Electroencephalography; Excitatory Amino Acid Agonists; Female; Glycolates; Hippocampus; Male; Mice; Mice, Inbred Strains; N-Methylaspartate; Neurons; Oximes; Parasympathetic Nervous System; Pentylenetetrazole; Pyridinium Compounds; Quinuclidines; Rats; Rats, Wistar; Seizures; Soman	2005
Anticonvulsant activity of Cotyledon orbiculata L. (Crassulaceae) leaf extract in mice. Journal of ethnopharmacology, 2007, May-30, Volume: 112, Issue:1 Topics: Animals; Anticonvulsants; Bicuculline; Convulsants; Crassulaceae; Dose-Response Relationship, Drug; Male; Mice; N-Methylaspartate; Pentylenetetrazole; Phytotherapy; Picrotoxin; Plant Extracts; Plant Leaves; Seizures	2007
Lacosamide, a novel anti-convulsant drug, shows efficacy with a wide safety margin in rodent models for epilepsy. Epilepsy research, 2007, Volume: 74, Issue:2-3 Topics: Acetamides; Animals; Anticonvulsants; Bicuculline; Cobalt; Convulsants; Electroshock; Epilepsies, Partial; Epilepsy; Epilepsy, Generalized; Epilepsy, Reflex; Excitatory Amino Acid Agonists; GABA Antagonists; Homocysteine; Kindling, Neurologic; Lacosamide; Male; Mice; N-Methylaspartate; Neurotoxicity Syndromes; Pentylenetetrazole; Picrotoxin; Rats; Rats, Sprague-Dawley; Status Epilepticus	2007
Glutamate transporters regulate extrasynaptic NMDA receptor modulation of Kv2.1 potassium channels. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2008, Aug-27, Volume: 28, Issue:35 Topics: Amino Acid Transport System X-AG; Analysis of Variance; Animals; Animals, Newborn; Cells, Cultured; Cerebral Cortex; Disks Large Homolog 4 Protein; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Hippocampus; Intracellular Signaling Peptides and Proteins; Male; Membrane Potentials; Membrane Proteins; N-Methylaspartate; Neurons; Organ Culture Techniques; Patch-Clamp Techniques; Pentylenetetrazole; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Seizures; Shab Potassium Channels; Synapses	2008
Paradoxical facilitation of pentylenetetrazole-induced convulsion susceptibility in mice lacking neuronal nitric oxide synthase. Neuroscience, 2009, Mar-17, Volume: 159, Issue:2 Topics: Animals; Convulsants; Disease Models, Animal; Dizocilpine Maleate; Dose-Response Relationship, Drug; Gene Expression Regulation; Imidazoles; Indazoles; Mice; Mice, Inbred C57BL; Mice, Knockout; N-Methylaspartate; Neuroprotective Agents; Nitric Oxide; Nitric Oxide Synthase Type I; Pentylenetetrazole; Quinoxalines; Seizures	2009
Validation of anticonvulsant and sedative activity of six medicinal plants. Epilepsy & behavior : E&B, 2009, Volume: 14, Issue:3 Topics: Animals; Anticonvulsants; Convulsants; Diazepam; Dose-Response Relationship, Drug; Electroshock; Epilepsy; Excitatory Amino Acid Agonists; Hypnotics and Sedatives; Isoniazid; Male; Medicine, African Traditional; Mice; N-Methylaspartate; Pentylenetetrazole; Picrotoxin; Plants, Medicinal; Sleep Initiation and Maintenance Disorders; Stereotyped Behavior; Strychnine	2009
Anticonvulsant activity of Nylandtia spinosa L. Dumont (Polygalaceae) aqueous and methanol leaf extracts in mice. Human & experimental toxicology, 2008, Volume: 27, Issue:11 Topics: Animals; Anticonvulsants; Bicuculline; Convulsants; Epilepsy, Generalized; Lethal Dose 50; Male; Methanol; Mice; N-Methylaspartate; Pentylenetetrazole; Picrotoxin; Plant Extracts; Plant Leaves; Polygalaceae; Seizures; Solvents; Water	2008
Anticonvulsant, anxiolytic, and sedative properties of the roots of Nauclea latifolia Smith in mice. Epilepsy & behavior : E&B, 2009, Volume: 15, Issue:4 Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Anxiety; Cameroon; Convulsants; Diazepam; Dose-Response Relationship, Drug; Electroshock; Excitatory Amino Acid Agonists; Fever; Hypnotics and Sedatives; Male; Mice; Motor Activity; N-Methylaspartate; Pentylenetetrazole; Plant Roots; Rubiaceae; Seizures; Sleep; Stress, Psychological; Strychnine	2009
Specificity of action of epileptogenic agents in diazepam-tolerant rats. Bulletin of experimental biology and medicine, 2009, Volume: 147, Issue:6 Topics: Analysis of Variance; Animals; Anticonvulsants; Brain; Diazepam; Excitatory Amino Acid Agonists; Kainic Acid; Male; N-Methylaspartate; Pentylenetetrazole; Rats; Rats, Wistar; Seizures	2009
Anticonvulsant effects of Searsia dentata (Anacardiaceae) leaf extract in rats. Phytotherapy research : PTR, 2010, Volume: 24, Issue:6 Topics: Anacardiaceae; Animals; Anticonvulsants; Bicuculline; Disease Models, Animal; Epilepsy; Kainic Acid; Male; N-Methylaspartate; Pentylenetetrazole; Plant Extracts; Plant Leaves; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Seizures	2010
Neurodevelopmental effects of chronic exposure to elevated levels of pro-inflammatory cytokines in a developing visual system. Neural development, 2010, Jan-12, Volume: 5 Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Avoidance Learning; Behavior, Animal; Convulsants; Cytokines; Dendrites; Electrophysiology; Excitatory Postsynaptic Potentials; GABA Antagonists; Interleukin-1beta; Interleukin-6; Larva; N-Methylaspartate; Nervous System; Neural Pathways; Neurons; Pentylenetetrazole; Retina; Seizures; Superior Colliculi; Synapses; Synaptic Transmission; Tectum Mesencephali; Time Factors; Tumor Necrosis Factor-alpha; Visual Pathways	2010
[EFfect of quercetin on the severity of chemically induced seizures and the content of heat shock protein 70 in the rat brain structures]. Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova, 2010, Volume: 96, Issue:3 Topics: Animals; Antioxidants; Ataxia; Behavior, Animal; Corpus Callosum; Excitatory Amino Acid Agonists; GABA Antagonists; Gene Expression Regulation; Hippocampus; HSP70 Heat-Shock Proteins; Male; N-Methylaspartate; Pentylenetetrazole; Quercetin; Rats; Rats, Wistar; Seizures; Severity of Illness Index	2010
Anticonvulsant activity of berberine, an isoquinoline alkaloid in mice. Epilepsy & behavior : E&B, 2010, Volume: 18, Issue:3 Topics: Animals; Anticonvulsants; Berberine; Diazepam; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Electroshock; Kainic Acid; Male; Mice; N-Methylaspartate; Pentylenetetrazole; Rotarod Performance Test; Seizures	2010
Exogenous protein Hsp70/Hsc70 can penetrate into brain structures and attenuate the severity of chemically-induced seizures. Journal of neurochemistry, 2010, Volume: 115, Issue:4 Topics: Animals; Anticonvulsants; Brain; Cattle; HSC70 Heat-Shock Proteins; HSP70 Heat-Shock Proteins; Humans; Male; N-Methylaspartate; Pentylenetetrazole; Prospective Studies; Protein Transport; Rats; Rats, Wistar; Recombinant Proteins; Seizures; Severity of Illness Index	2010
Anticonvulsant profile of the alkaloids (+)-erythravine and (+)-11-α-hydroxy-erythravine isolated from the flowers of Erythrina mulungu Mart ex Benth (Leguminosae-Papilionaceae). Epilepsy & behavior : E&B, 2011, Volume: 20, Issue:3 Topics: Animals; Anticonvulsants; Bicuculline; Chi-Square Distribution; Disease Models, Animal; Dose-Response Relationship, Drug; Fabaceae; Flowers; Heterocyclic Compounds, 4 or More Rings; Injections, Intraventricular; Kainic Acid; Male; N-Methylaspartate; Pentylenetetrazole; Phytotherapy; Plant Extracts; Rats; Rats, Wistar; Reaction Time; Seizures	2011
Behavioral characterization of knockin mice with mutations M287L and Q266I in the glycine receptor α1 subunit. The Journal of pharmacology and experimental therapeutics, 2012, Volume: 340, Issue:2 Topics: 1-Butanol; Alcohol Drinking; Alcohol Withdrawal Seizures; Amino Acid Substitution; Animals; Behavior, Animal; Central Nervous System Depressants; Conditioning, Classical; Drug Synergism; Eating; Ethanol; Female; Food Preferences; Gene Knock-In Techniques; Male; Mice; Mice, 129 Strain; Mice, Inbred C57BL; Mice, Transgenic; Motor Skills; Mutation; N-Methylaspartate; Nicotine; Pentylenetetrazole; Quinine; Receptors, Glycine; Reflex, Righting; Reflex, Startle; Rotarod Performance Test; Saccharin; Seizures; Sex Characteristics; Strychnine; Taste Perception	2012
Endogenous ACh effects on NMDA-induced interictal-like discharges along the septotemporal hippocampal axis of adult rats and their modulation by an early life generalized seizure. Epilepsia, 2012, Volume: 53, Issue:5 Topics: Acetylcholine; Analysis of Variance; Animals; Atropine; Cholinesterase Inhibitors; Convulsants; Disease Models, Animal; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Hippocampus; In Vitro Techniques; Male; Muscarinic Antagonists; N-Methylaspartate; Neurons; Pentylenetetrazole; Physostigmine; Rats; Rats, Sprague-Dawley; Seizures; Sex Factors; Valine	2012
Protective activity of α-lactoalbumin (ALAC), a whey protein rich in tryptophan, in rodent models of epileptogenesis. Neuroscience, 2012, Dec-13, Volume: 226 Topics: Animals; Convulsants; Epilepsy; Epilepsy, Absence; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Hippocampus; Kynurenic Acid; Lactalbumin; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Milk Proteins; N-Methylaspartate; Pentylenetetrazole; Pilocarpine; Rats; Tryptophan; Whey Proteins	2012
Mygalin: a new anticonvulsant polyamine in acute seizure model and neuroethological schedule. Central nervous system agents in medicinal chemistry, 2013, Volume: 13, Issue:2 Topics: Acute Disease; Animals; Anticonvulsants; Cognition; Diazepam; Dizocilpine Maleate; Drug Evaluation, Preclinical; Epilepsy, Tonic-Clonic; Excitatory Amino Acid Antagonists; Exploratory Behavior; Locomotion; Male; Maze Learning; N-Methylaspartate; Pentylenetetrazole; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Rotarod Performance Test; Spermidine	2013
Combined blockade of NMDA and AMPA receptors prevents acute kainate seizures and chronic kainate lethality in rats. Bulletin of experimental biology and medicine, 2014, Volume: 157, Issue:1 Topics: Adamantane; Amines; Animals; Anticonvulsants; Convulsants; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Injections, Intramuscular; Kainic Acid; Male; Memantine; N-Methylaspartate; Neuroprotective Agents; Pentylenetetrazole; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Seizures; Survival Analysis	2014
Effects of D-penicillamine on pentylenetetrazole-induced seizures in mice: involvement of nitric oxide/NMDA pathways. Epilepsy & behavior : E&B, 2014, Volume: 39 Topics: Animals; Anticonvulsants; Convulsants; Disease Models, Animal; Male; Mice; N-Methylaspartate; Nitric Oxide; Nitric Oxide Synthase; Penicillamine; Pentylenetetrazole; Seizures; Signal Transduction	2014
Structure-activity relationship for the anticonvulsant effects of organic solvents. Neurotoxicology, 2016, Volume: 57 Topics: Animals; Anticonvulsants; Convulsants; Disease Models, Animal; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Male; Mice; N-Methylaspartate; Pentylenetetrazole; Seizures; Solvents; Structure-Activity Relationship	2016
Transient Switching of NMDA-Dependent Long-Term Synaptic Potentiation in CA3-CA1 Hippocampal Synapses to mGluR Cellular and molecular neurobiology, 2019, Volume: 39, Issue:2 Topics: Animals; CA1 Region, Hippocampal; CA3 Region, Hippocampal; Excitatory Postsynaptic Potentials; Long-Term Potentiation; Maze Learning; N-Methylaspartate; Pentylenetetrazole; Rats, Wistar; Receptors, AMPA; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Seizures; Spatial Memory; Synapses	2019
Interaction of morphine tolerance with pentylenetetrazole-induced seizure threshold in mice: The role of NMDA-receptor/NO pathway. Epilepsy & behavior : E&B, 2020, Volume: 112 Topics: Animals; Anticonvulsants; Dose-Response Relationship, Drug; Mice; Morphine; N-Methylaspartate; NG-Nitroarginine Methyl Ester; Nitric Oxide; Pentylenetetrazole; Receptors, N-Methyl-D-Aspartate; Seizures	2020
Acteoside Isolated from Colebrookea oppositifolia Smith Attenuates Epilepsy in Mice Via Modulation of Gamma-Aminobutyric Acid Pathways. Neurotoxicity research, 2020, Volume: 38, Issue:4 Topics: Animals; Anticonvulsants; Dose-Response Relationship, Drug; Epilepsy; GABA Antagonists; gamma-Aminobutyric Acid; Glucosides; Lamiaceae; Male; Mice; N-Methylaspartate; Pentylenetetrazole; Phenols; Plant Extracts; Plant Roots; Signal Transduction	2020
Neuroprotective effect of sumatriptan in pentylenetetrazole-induced seizure is mediated through N-methyl-D-aspartate/nitric oxide and cAMP response element-binding protein signaling pathway. Fundamental & clinical pharmacology, 2022, Volume: 36, Issue:2 Topics: Animals; Cyclic AMP Response Element-Binding Protein; Mice; N-Methylaspartate; Neuroprotective Agents; Nitric Oxide; Pentylenetetrazole; Seizures; Signal Transduction; Sumatriptan	2022
Anticonvulsive Effects and Pharmacokinetic Profile of Cannabidiol (CBD) in the Pentylenetetrazol (PTZ) or N-Methyl-D-Aspartate (NMDA) Models of Seizures in Infantile Rats. International journal of molecular sciences, 2021, Dec-22, Volume: 23, Issue:1 Topics: Animals; Anticonvulsants; Brain; Cannabidiol; Disease Models, Animal; Epilepsy; Male; N-Methylaspartate; Pentylenetetrazole; Rats; Rats, Wistar; Seizures	2021
The Role of the NMDA Receptor in the Anticonvulsant Effect of Ellagic Acid in Pentylenetetrazole-Induced Seizures in Male Mice. Behavioural neurology, 2022, Volume: 2022 Topics: Animals; Anticonvulsants; Dose-Response Relationship, Drug; Ellagic Acid; Ketamine; Male; Mice; N-Methylaspartate; Pentylenetetrazole; Receptors, N-Methyl-D-Aspartate; Seizures	2022
Pentylenetetrazole preconditioning attenuates severity of status epilepticus induced by lithium-pilocarpine in male rats: evaluation of opioid/NMDA receptors and nitric oxide pathway. Pharmacological reports : PR, 2022, Volume: 74, Issue:4 Topics: Analgesics, Opioid; Animals; Anticonvulsants; Enzyme Inhibitors; Lithium; Male; N-Methylaspartate; Nitric Oxide; Pentylenetetrazole; Pilocarpine; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid; Signal Transduction; Status Epilepticus	2022