n-methylaspartate has been researched along with ketamine in 234 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 44 (18.80) | 18.7374 |
| 1990's | 79 (33.76) | 18.2507 |
| 2000's | 46 (19.66) | 29.6817 |
| 2010's | 44 (18.80) | 24.3611 |
| 2020's | 21 (8.97) | 2.80 |
| Authors | Studies |
|---|---|
| Fukuda, T; Irifune, M; Nomoto, M; Shimizu, T | 1 |
| Sedlácek, J | 3 |
| Henry, JL; Hong, YG | 1 |
| Henry, JL; Hong, Y | 1 |
| Barun, S; Dalkara, T; Erdemli, G; Onur, R | 1 |
| Albrecht, RF; Hoffman, WE; Kochs, E; Pelligrino, D; Schulte am Esch, J; Werner, C | 1 |
| Kalant, H; Khanna, JM; Mihic, SJ; Shah, G; Weiner, J; Wu, PH | 1 |
| Baimbridge, KG; Church, J; Shacklock, JA | 1 |
| Wayman, CP; Wilson, JF | 1 |
| Huang, JC; Marshall, J; Salt, TE; Voaden, MJ | 1 |
| Carlsson, A; Carlsson, M; Svensson, A | 1 |
| Brent, PJ | 1 |
| Daló, NL; Larson, AA | 1 |
| Millan, MJ | 1 |
| Davies, JA; Lancaster, JM | 1 |
| Lo, EH; Steinberg, GK; Sun, GH | 1 |
| Kulkarni, SK; Nayar, U; Sharma, AC | 1 |
| Kulkarni, SK; Nayar, U; Sharma, AC; Thorat, SN | 1 |
| Baimbridge, KG; Kessler, M; Lynch, G; Oliver, MW; Shacklock, JA | 1 |
| Hestrin, S; Nicoll, RA; Sah, P | 1 |
| Chaki, S; Muramatsu, M; Otomo, S; Usuki-Ito, C | 1 |
| Egert, U; Kossel, A; Rauschecker, JP | 1 |
| Heinemann, U; Mudrick, LA | 1 |
| Catalin, D; Cherkaoui, N; Jean, A; Kessler, JP | 1 |
| Gross, GW; Lucas, JH; Wang, GF | 1 |
| Mohri, T; Suzuki, R; Takadera, T | 1 |
| Church, J; Zeman, S | 1 |
| Banczerowski-Pelyhe, I; Tarnawa, I; Világi, I | 1 |
| Denavit-Saubié, M; Foutz, AS; Pierrefiche, O | 1 |
| Carlsson, M; Svensson, A | 1 |
| Feig, S; Lipton, P | 1 |
| Daniell, LC | 1 |
| France, CP; Winger, GD; Woods, JH | 1 |
| MacDonald, JF; Miljkovic, Z; Pennefather, P | 1 |
| Rothman, S | 1 |
| Harris, KM; Miller, RJ; Reynolds, IJ | 1 |
| Rao, TS; Wood, PL | 1 |
| Iversen, SD; Oles, RJ; Preston, C; Singh, L; Tricklebank, MD | 1 |
| Herberg, LJ; Rose, IC | 1 |
| Iwasaki, M | 1 |
| Miller, RJ; Reynolds, IJ | 1 |
| Haberly, LB; Hoffman, WH | 1 |
| Davidoff, RA; Hackman, JC; Zhang, DX | 1 |
| Halliwell, RF; Lambert, JJ; Peters, JA | 1 |
| France, CP; Ornstein, P; Woods, JH | 1 |
| Johnston, MV; McDonald, JW; Roeser, NF; Silverstein, FS | 1 |
| Headley, PM; Parsons, CG; West, DC | 1 |
| Amrick, CL; Bennett, DA; Bernard, PS | 1 |
| Aram, JA; Church, J; Davies, SN; Lodge, D; Martin, D; Millar, JD | 1 |
| Champagnat, J; Denavit-Saubié, M; Foutz, AS | 1 |
| Koek, W; Winger, GD; Woods, JH | 1 |
| De Prins, E; Marrannes, R; Wauquier, A; Willems, R | 1 |
| Lodge, D; Martin, D | 3 |
| Harrison, NL; Simmonds, MA | 1 |
| Johnson, KM; Snell, LD | 1 |
| MacDonald, JF; Miljkovic, Z; Schneiderman, JH | 1 |
| Lees, GJ | 2 |
| de Carolis, AS; Frank, C; Sagratella, S | 1 |
| Aram, JA; Lodge, D | 1 |
| Davies, SN; Drejer, J; Fletcher, EJ; Honoré, T; Jacobsen, P; Lodge, D; Nielsen, FE | 1 |
| Lee, M; Strahlendorf, HK; Strahlendorf, JC | 1 |
| Mayer, ML; Vyklický, L; Westbrook, GL | 1 |
| Berry, SC; Church, J; Lodge, D | 1 |
| Blake, J; Church, J; Davies, SN; Jacobson, AE; Lessor, RA; Lodge, D; Rice, KC | 1 |
| Prasad, SK; Salt, TE; Wilson, DG | 1 |
| Boast, CA; Pastor, G | 1 |
| Blake, JC; Church, J; Davies, SN; Lodge, D; Martin, D | 1 |
| Iversen, LL; Kemp, JA; Knight, AR; Priestley, T; Wong, EH; Woodruff, GN | 1 |
| Brady, RJ; Swann, JW | 1 |
| Johnston, GA; Lodge, D | 1 |
| Biscoe, TJ; Burton, NR; Duchen, MR | 1 |
| Berry, SC; Dawkins, SL; Lodge, D | 1 |
| Anis, NA; Berry, SC; Lodge, D | 1 |
| Anis, NA; Berry, SC; Burton, NR; Lodge, D | 1 |
| Anis, NA; Burton, NR; Lodge, D | 1 |
| Anderson, LA; Bergstrom, DA; Kelland, MD; Soltis, RP; Walters, JR | 1 |
| Fedele, E; Raiteri, M; Versace, P | 1 |
| Dickie, BG; Greenfield, SA; Jones, SA; Klegeris, A | 1 |
| Arendt-Nielsen, L; Bak, P; Bjerring, P; Fischer, M; Petersen-Felix, S; Zbinden, AM | 1 |
| Anantharam, V; Rodríguez-Paz, JM; Treistman, SN | 1 |
| Grosche, J; Kettenmann, H; Müller, T; Ohlemeyer, C | 1 |
| Henry, JL; Radhakrishnan, V | 1 |
| Gonzales, JM; Irvine, S; Loeb, AL; Reichard, PS | 1 |
| Pike, NV; Wayman, CP; Wilson, JF | 1 |
| Durand, J | 1 |
| Scholfield, CN; Yassin, M | 1 |
| Chau, A; Kalant, H; Khanna, JM; Morato, GS; Shah, G | 1 |
| Hargreaves, RJ; Hill, RG; Iversen, LL | 1 |
| Aguado, L; del Valle, R; Gómez, J; Pérez, L; San Antonio, A | 1 |
| Alford, S; Dubuc, R | 1 |
| Gruner, R; Lodge, D; Millar, J; Parsons, CG; Rozental, J | 1 |
| Chizh, BA; Headley, PM | 2 |
| Chiodo, LA; Kelland, MD | 1 |
| Arai, T; Kimura, H; Mori, K; Nakao, S; Tooyama, I; Yasuhara, O | 1 |
| Kubová, H; Mares, P | 1 |
| Chiou, AL; Lin, JC; Wang, Y; Yang, ST | 1 |
| Clapp, I; Laidlaw, S; Mitchell, IJ; Waters, CM | 1 |
| Armstrong, JD; Barb, CR; Campbell, RM; Estienne, MJ; Harter-Dennis, JM; Hartsock, TG | 1 |
| Barb, CR; Estienne, MJ; Kraeling, RR; Popwell, JM; Rampacek, GB; Utley, RV; Whitley, NC | 1 |
| Adachi, T; Kimura, H; Kurata, J; Mori, K; Murakawa, M; Nakao, S; Shibata, M; Shichino, T; Shinomura, T; Tocyama, I | 1 |
| Arendt-Nielsen, L; Nielsen, J; Petersen-Felix, S; Schnider, TW; Zbinden, AM | 1 |
| Krishtal, OA; Panchenko, VA; Parsons, CG; Pinchenko, VO; Tsyndrenko, AY | 1 |
| Chau, A; Khanna, JM; Shah, G | 1 |
| Bieger, D; Lu, WY | 1 |
| Cai, YC; Fan, GH; Jiang, LZ; Ma, L; Pei, G; Zhao, J | 1 |
| Ando, H; Kagawa, H; Sakube, Y | 1 |
| Fu, ES; Miguel, R; Scharf, JE | 1 |
| Lovinger, DM; Peoples, RW; Weight, FF; White, G | 1 |
| Chau, A; Kalant, H; Khanna, JM; Shah, G | 1 |
| Kitamura, R; Miyawaki, I; Mori, K; Nakamura, K; Yokubol, B | 1 |
| Bielavska, E; Bures, J; Gallo, M; Roldán, G | 1 |
| Fallon, MT; O'Neill, B | 1 |
| Ellershaw, JE; Makin, MK | 1 |
| Lanthorn, TH; Mealing, GA; Morley, P; Murray, CL; Small, DL | 1 |
| Chatterjee, SS; Krishtal, OA; Lishko, PV; Maximyuk, OP; Nöldner, M | 1 |
| Besson, JM; Montagne-Clavel, J; Rivot, JP; Sousa, A | 1 |
| Amabeoku, GJ | 1 |
| Doat, M; Rabin, RA; Winter, JC | 1 |
| Altaf, S; Asif, M; Naseem, AA; Qayyum, M; Rasul, Z; Rizvi, SS | 1 |
| Dohi, S; Iida, H; Nagase, K; Ohata, H | 1 |
| Lauretti, GR; Oliveira, AP; Paccola, CA; Rodrigues, AM | 1 |
| Carpy, A; Elhallaoui, M; Laguerre, M; Ouazzani, FC | 1 |
| Grant, KA; Jordan, K; Szeliga, KT; Vivian, JA; Waters, CA | 1 |
| Akman, H; Gündüz, M; Ozalevli, M; Unlügenç, H | 1 |
| Avila, MT; Lahti, AC; Tamminga, CA; Thaker, GK; Weiler, MA | 1 |
| Baghdoyan, HA; Lydic, R | 1 |
| Davis, SA; Gold, LH; Gutierrez, T; Taffe, MA | 1 |
| Franks, NP; Ma, D; Maze, M; Wilhelm, S | 1 |
| Baker, AK; Hoffmann, VL; Meert, TF | 1 |
| Shi, WX; Zhang, XX | 1 |
| Anderson, JJ; Baccei, CS; Bristow, LJ; Lorrain, DS; Varney, MA | 1 |
| Aithal, HP; Kinjavdekar, P; Singh, GR | 1 |
| Barb, CR; Estienne, MJ | 1 |
| Archer, T; Fredriksson, A | 1 |
| Alonso, TJ; Castro Fuentes, R; García Dopico, J; González Hernández, T; Perdomo Díaz, J; Rodríguez Díaz, M | 1 |
| Abel, T; Connolly, PM; Gur, RE; Kahn, JB; Kanes, SJ; Liang, Y; Maxwell, C; Siegel, SJ; Turetsky, BI | 1 |
| Sun, W; Wessinger, WD | 1 |
| Bermpohl, F; Boeker, H; Grimm, S; Hell, D; Marcar, VL; Martin, E; Northoff, G; Richter, A; Wahl, C | 1 |
| Kiyosue, K; Nakayama, K; Taguchi, T | 1 |
| Miao, B; Yin, XH; Zhang, GY; Zhang, QG | 1 |
| Ackenheil, M; Offenbaecher, M | 1 |
| Bullmore, ET; Fletcher, PC; Honey, GD; Honey, RA; Hu, X; Kumaran, D; Pomarol-Clotet, E; Rugg, MD; Sharar, SR; Simons, JS; Turner, DC | 1 |
| Baker, LE; Brandt, AE; Poling, A; Van Tilburg, TJ | 1 |
| Ishida, A; Ohyashiki, T; Takadera, T | 1 |
| Bartfai, T; Behrens, MM; Conti, B; Davis, CN; Kinney, JW; Tabarean, I | 1 |
| Chen, Z; Ge, QF; Hu, X; Huang, XJ; Liu, JR; Song, Y; Wang, ML; Wei, EQ; Zhang, WP | 1 |
| Chizh, BA; Christoph, T; Englberger, W; Parsons, CG; Schiene, K | 1 |
| Arendt-Nielsen, L; Cairns, BE; Dong, XD; Mann, MK; Sessle, BJ; Svensson, P | 1 |
| Mashimo, T; Shibuta, S; Varathan, S | 1 |
| Badaras, R; Ivaskevicius, J; Jovaisa, T; Laurinenas, G; Sipylaite, J; Vosylius, S | 1 |
| Jackson, AC; Scott, CA; Ward, CA; Weli, SC | 1 |
| Fonteles, MM; Freitas, RM; Sousa, FC; Viana, GS | 1 |
| Chen, Z; Ding, Q; Wei, EQ; Zhang, WP; Zhang, YJ | 1 |
| Assis, MA; Fonteles, MM; Freitas, RL; Freitas, RM; Pereira, MB; Silva, RF; Takahashi, RN | 1 |
| Meyer, PJ; Phillips, TJ | 1 |
| de Lima, VM; Hanke, W | 1 |
| Eriksson, P; Fredriksson, A; Gordh, T; Pontén, E | 1 |
| Tsai, GE | 1 |
| Eisenach, J; Horais, KA; Lafranco, L; Malkmus, S; Rathbun, M; Tozier, N; Yaksh, TL | 1 |
| Arslantas, A; Koken, T; Salman, B; Uzuner, K; Vural, M; Yazihan, N | 1 |
| Carlsson, C; Chen, D; Harakal, C; Kamel, IR; Wendling, KS; Wendling, WW | 1 |
| Chambers, JP; Johnson, CB; Lizarraga, I | 1 |
| Dehpour, AR; Ghasemi, M; Raza, M | 1 |
| Eilers, H; Larson, MD | 1 |
| Alania, M; Chikovani, M; Chkhartishvili, B; Doreulee, N; Mitaishvili, E | 1 |
| Fan, M; Lam, WP; Li, Z; Lu, G; Mak, YT; Wai, MS; Yeung, LY; Yew, DT | 1 |
| Ameli, R; Brutsche, NE; DiazGranados, N; Henter, ID; Ibrahim, LA; Luckenbaugh, DA; Machado-Vieira, R; Zarate, CA | 1 |
| Brutsche, NE; Diazgranados, N; Ibrahim, L; Kammerer, WA; Khalife, S; Kronstein, P; Luckenbaugh, DA; Machado-Vieira, R; Manji, HK; Newberg, A; Quezado, Z; Salvadore, G; Zarate, CA | 1 |
| Aguirre, CA; English, BK; Lazar, L; Meals, E; Rayburn, MS; Shapley, RK; Spentzas, T; Walker, BS | 1 |
| Campbell, LL; Edmands, SD; Hall, AC; Hokenson, KE; Kim, SA; McKeon, JE; Sherrill, H; Stackpole, EE; Suarez, C; Tyson, JA | 1 |
| Baumann, J; Diazgranados, N; Ibrahim, L; Luckenbaugh, DA; Machado-Vieira, R; Mallinger, AG; Zarate, CA | 1 |
| Halder, S; Khanna, N; Mehta, AK; Sharma, KK; Tandon, OP | 1 |
| Canning, BJ; Hilton, ECY; Saulsberry, L; Smith, JA | 1 |
| Gartside, SE; McCardle, CE | 1 |
| Hsieh, WK; Keng, NT; Lai, CC; Lin, HH; Lin, HR | 1 |
| Cryan, JF; Dinan, TG; O' Connor, RM; Pusceddu, MM | 1 |
| Kaster, MP; Machado, DG; Rodrigues, AL; Santos, AR | 1 |
| Pathak, S; Smith, MA | 1 |
| Brutsche, N; Duncan, WC; Sarasso, S; Selter, J; Zarate, CA | 1 |
| Halder, S; Khanna, N; Mehta, AK; Sharma, KK; Singh, UR; Tandon, OP | 1 |
| Chen, SJ; Huang, MH; Lin, KH; Shen, AY; Wu, FT; Wu, SN | 1 |
| Balleine, BW; Bradfield, LA | 1 |
| Bo, L; Dong, Z; Huang, L; Kang, R; Li, X; Liu, Y; Zhang, P | 1 |
| Hillhouse, TM; Porter, JH | 1 |
| Carson, RE; Castner, SA; Gunn, RN; Herdon, H; Huang, Y; Laruelle, M; Murthy, NV; Rabiner, EA; Ridler, K; Roberts, BM; Weinzimmer, DP; Williams, GV; Zheng, MQ | 1 |
| Adeyemi, OI; Akanmu, MA; Owolabi, RA | 1 |
| Anand, KJ; Dong, C; Rovnaghi, CR | 1 |
| Bachmann, LM; Brunner, F; Kessels, AG; Perez, RS; Wertli, MM | 1 |
| Luckenbaugh, DA; Lukkahati, N; Machado-Vieira, R; Niciu, MJ; Nugent, AC; Ortiz, R; Saligan, LN; Zarate, CA | 1 |
| Lloyd, RL; Pekary, AE; Sattin, A | 1 |
| Hanig, JP; Liu, F; Patterson, TA; Paule, MG; Rainosek, SW; Sadovova, N; Slikker, W; Wang, C | 1 |
| Fu, LS; Liu, GL; Liu, Z; Meng, C; Xia, HM; Xu, YN; Zhang, M; Zhang, SH; Zhang, Z | 1 |
| Pitsikas, N; Touzlatzi, N; Trevlopoulou, A | 1 |
| Cortés, P; Harraz, MM; Snyder, SH; Tyagi, R | 1 |
| Katz, DM; Mather, RJ; Menniti, FS | 1 |
| Machado-Vieira, R; Zarate, CA | 1 |
| Ashkenazi, S; Berent, E; Weizman, A; Yuhas, Y | 1 |
| Akbarian, R; Chamanara, M; Dehpour, AR; Ghasemi, M; Imran-Khan, M; Norouzi-Javidan, A; Ostadhadi, S | 1 |
| Gould, TD; Moaddel, R; Moore, CE; Morris, PJ; Thomas, CJ; Zanos, P; Zarate, CA | 1 |
| Deyama, S; Duman, RS; Fogaça, MV; Fukumoto, K; Kato, T; Li, XY | 1 |
| Bo, L; Duan, X; Huang, L; Jiang, S; Jin, W; Kang, R; Li, X; Wang, Y; Wu, J; Zhang, R | 1 |
| Gilbert, JR; Nugent, AC; Wills, KE; Yarrington, JS; Zarate, CA | 1 |
| Brooks, G; Hasekiu, E; Ingle Gonzalez, JE; Kusi, M; Noakes, J | 1 |
| Farber, NB | 1 |
| Fagiolini, M; Hensch, TK; Picard, N; Takesian, AE | 1 |
| Fariborzi, M; Higley, MJ; Lur, G | 1 |
| Aguilera, AH; Dreier, JP; Hartings, JA; Herrera, MG; Kentar, M; Kola, V; Kunzmann, K; Lemale, CL; Major, S; Olivares-Rivera, A; Sakowitz, OW; Sánchez-Porras, R; Santos, E; Uhlmann, L; Unterberg, AW; Woitzik, J; Zerelles, R | 1 |
| Hashimoto, K | 1 |
| Ferrarelli, F | 1 |
| Chen, H; Chen, Y; He, Y; Luo, T; Xu, W; Yuan, Y; Zheng, S | 1 |
| Li, S; Liu, H; Niu, X; Zheng, S | 1 |
| Georgiou, P; Gould, TD; Rudolph, U; Thompson, SM; Troppoli, TA; Zanos, P | 1 |
| Amini-Khoei, H; Boroujeni, SN; Lorigooini, Z; Rahimi-Madiseh, M; Taji, M | 1 |
| Alami, A; Alexander, GC; Mattison, DR; Moore, TJ | 1 |
| Kocsis, B; Mofleh, R; Staszelis, A | 1 |
| Cook, J; Halaris, A | 1 |
| Chen, J; Hu, B; Shen, M; Wang, F; Yang, Y; Zhou, Q; Zou, X | 1 |
| Bastlund, JF; Christensen, SR; De Meyer, K; Gabay, A; Gijsen, S; Herrik, KF; Mehta, MA; Nottage, JF | 1 |
| Bustillo, JR; Kruse, AO | 1 |
| Brown, KA; Georgiou, P; Gould, TD; Thompson, SM; Yuan, P; Zanos, P; Zarate, CA | 1 |
| Hirota, K; Hu, C; Ishikawa, M; Iwasaki, M; Ma, D; Saito, J; Sun, Q; Wu, L; Zao, H | 1 |
| Curic, S; Haaf, M; Leicht, G; Mulert, C; Rauh, J; Steinmann, S | 1 |
| Bhatia, A; Cao, X; Curtis, K; Dahan, A; Gilron, I; Hoydonckx, Y; Kara, J; Khan, J; Narouze, S; Singh, M | 1 |
| Aglio, LS; Akeju, O; Balanza, GA; Brown, EN; Cash, SS; Cosgrove, GR; Eskandar, EN; Lewis, LD; Paulk, AC; Peled, N; Peterfreund, RA; Purdon, PL; Richardson, RM; Santa Cruz Mercado, LA; Soper, D; Tian, F; Williams, ZM; Zelmann, R; Zhou, DW | 1 |
| Cao, SH; Gu, JW; Han, XY; Jiang, CT; Nie, C; Tian, KX; Yu, S; Zhao, ZP | 1 |
| Delis, A; Ettinger, U; Hurlemann, R; Lehmann, M; Neumann, C; Philipsen, A; Schultz, J; Wasserthal, S | 1 |
| Destexhe, A; Susin, E | 1 |
| Gardier, AM; Guilloux, JP; Nguyen, TML | 1 |
6 review(s) available for n-methylaspartate and ketamine
| Article | Year |
|---|---|
Neuroprotective NMDA antagonists: the controversy over their potential for adverse effects on cortical neuronal morphology.
Topics: Animals; Cell Survival; Cerebral Cortex; Dextrorphan; Dizocilpine Maleate; Dose-Response Relationship, Drug; Energy Metabolism; Excitatory Amino Acid Antagonists; Glycine; Gyrus Cinguli; Ketamine; N-Methylaspartate; Neurons; Phencyclidine; Rats; Receptors, N-Methyl-D-Aspartate; Vacuoles | 1994 |
Current trends in neuropathic pain treatments with special reference to fibromyalgia.
Topics: Analgesics; Analgesics, Opioid; Anticonvulsants; Fibromyalgia; Humans; Ketamine; N-Methylaspartate; Needs Assessment; Neuralgia | 2005 |
Rational pain management in complex regional pain syndrome 1 (CRPS 1)--a network meta-analysis.
Topics: Adrenal Cortex Hormones; Aged; Amines; Analgesics; Cyclohexanecarboxylic Acids; Diphosphonates; Drug Utilization; Follow-Up Studies; Gabapentin; gamma-Aminobutyric Acid; Humans; Ketamine; Middle Aged; N-Methylaspartate; Pain Management; Practice Guidelines as Topic; Randomized Controlled Trials as Topic; Reflex Sympathetic Dystrophy; Treatment Outcome; Vasodilator Agents | 2014 |
Safety and effectiveness of NMDA receptor antagonists for depression: A multidisciplinary review.
Topics: Animals; Depression; Humans; Ketamine; Mammals; N-Methylaspartate; Phencyclidine; Receptors, N-Methyl-D-Aspartate | 2022 |
Glutamatergic dysfunction in Schizophrenia.
Topics: Dopamine; Glutamic Acid; Humans; Ketamine; N-Methylaspartate; Schizophrenia | 2022 |
[Ketamine: a neuropsychotropic drug with an innovative mechanism of action].
Topics: Animals; Antidepressive Agents; Depressive Disorder, Major; Glutamic Acid; Ketamine; N-Methylaspartate; Pharmaceutical Preparations; Receptors, AMPA | 2023 |
19 trial(s) available for n-methylaspartate and ketamine
| Article | Year |
|---|---|
The effect of N-methyl-D-aspartate antagonist (ketamine) on single and repeated nociceptive stimuli: a placebo-controlled experimental human study.
Topics: Analgesics; Cross-Over Studies; Double-Blind Method; Electric Stimulation; Electromyography; Evoked Potentials; Humans; Ketamine; Lasers; N-Methylaspartate; Nociceptors; Pain; Pain Threshold; Physical Stimulation; Placebos; Pressure; Receptors, N-Methyl-D-Aspartate; Reflex; Sural Nerve | 1995 |
Effect of racemic mixture and the (S+)-isomer of ketamine on temporal and spatial summation of pain.
Topics: Adult; Anesthetics, Dissociative; Cross-Over Studies; Double-Blind Method; Electric Stimulation; Hot Temperature; Humans; Ketamine; N-Methylaspartate; Pain; Pain Threshold; Physical Stimulation; Pressure; Reaction Time; Skin Temperature; Stereoisomerism | 1996 |
Preemptive ketamine decreases postoperative narcotic requirements in patients undergoing abdominal surgery.
Topics: Abdomen; Analgesia, Patient-Controlled; Double-Blind Method; Excitatory Amino Acid Agonists; Female; Humans; Ketamine; Male; Middle Aged; Morphine; N-Methylaspartate; Pain Measurement; Pain, Postoperative; Premedication | 1997 |
Ketamine, not propofol, attenuates cerebrovascular response to carbon dioxide in humans with isoflurane anesthesia.
Topics: Adult; Anesthesia, Inhalation; Anesthetics, Inhalation; Anesthetics, Intravenous; Blood Flow Velocity; Blood Pressure; Carbon Dioxide; Cerebrovascular Circulation; Female; Heart Rate; Humans; Isoflurane; Ketamine; Male; Middle Cerebral Artery; N-Methylaspartate; Propofol | 2001 |
The effect of transdermal nitroglycerin on spinal S(+)-ketamine antinociception following orthopedic surgery.
Topics: Adjuvants, Anesthesia; Administration, Cutaneous; Adult; Analgesia, Epidural; Analgesics; Anesthesia, Epidural; Anesthesia, Spinal; Double-Blind Method; Female; Humans; Ketamine; Knee Joint; Male; Middle Aged; N-Methylaspartate; Nitric Oxide Donors; Nitroglycerin; Orthopedic Procedures; Pain Measurement; Pain, Postoperative | 2001 |
A comparative study on the analgesic effect of tramadol, tramadol plus magnesium, and tramadol plus ketamine for postoperative pain management after major abdominal surgery.
Topics: Abdomen; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Anesthetics, Combined; Double-Blind Method; Female; Humans; Ketamine; Magnesium Sulfate; Male; Middle Aged; N-Methylaspartate; Pain Measurement; Pain, Postoperative; Tramadol | 2002 |
Interaction between epidurally administered ketamine and pethidine in dogs.
Topics: Analgesics; Analgesics, Opioid; Animals; Dogs; Drug Interactions; Female; Heart Rate; Injections, Epidural; Ketamine; Male; Meperidine; N-Methylaspartate; Pain, Postoperative; Respiration | 2003 |
NMDA hypofunction in the posterior cingulate as a model for schizophrenia: an exploratory ketamine administration study in fMRI.
Topics: Adult; Consciousness Disorders; Double-Blind Method; Excitatory Amino Acid Antagonists; Female; Gyrus Cinguli; Humans; Ketamine; Limbic System; Magnetic Resonance Imaging; Male; Memory; N-Methylaspartate; Reaction Time; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Semantics; Surveys and Questionnaires | 2005 |
Impairment of specific episodic memory processes by sub-psychotic doses of ketamine: the effects of levels of processing at encoding and of the subsequent retrieval task.
Topics: Adolescent; Adult; Arousal; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Infusions, Intravenous; Ketamine; Male; Memory; Middle Aged; N-Methylaspartate; Retention, Psychology; Verbal Learning | 2005 |
Effects of ketamine on precipitated opiate withdrawal.
Topics: Adolescent; Adult; Anesthesia, General; Anesthetics, Dissociative; Cardiovascular System; Data Interpretation, Statistical; Double-Blind Method; Excitatory Amino Acid Antagonists; Female; Humans; Hydrocortisone; Infusions, Intravenous; Ketamine; Male; Morphine; N-Methylaspartate; Narcotic Antagonists; Narcotics; Placebos; Prospective Studies; Substance Withdrawal Syndrome; Surveys and Questionnaires; Time Factors; Treatment Outcome | 2006 |
The effect of ketamine and nitrous oxide on the human pupillary light reflex during general anesthesia.
Topics: Adjuvants, Anesthesia; Adult; Aged; Anesthesia, General; Blood Pressure; Electroencephalography; Female; Heart Rate; Humans; Ketamine; Light; Male; Middle Aged; N-Methylaspartate; Neuromuscular Agents; Nitrous Oxide; Pupil; Receptors, N-Methyl-D-Aspartate; Reflex, Pupillary; Time Factors | 2010 |
Rapid resolution of suicidal ideation after a single infusion of an N-methyl-D-aspartate antagonist in patients with treatment-resistant major depressive disorder.
Topics: Adult; Antidepressive Agents; Depression; Depressive Disorder, Major; Diagnostic and Statistical Manual of Mental Disorders; Excitatory Amino Acid Antagonists; Female; Humans; Infusions, Intravenous; Ketamine; Male; Middle Aged; N-Methylaspartate; Psychiatric Status Rating Scales; Suicidal Ideation; Time Factors; Treatment Outcome | 2010 |
A randomized add-on trial of an N-methyl-D-aspartate antagonist in treatment-resistant bipolar depression.
Topics: Adolescent; Adult; Aged; Bipolar Disorder; Diagnostic and Statistical Manual of Mental Disorders; Double-Blind Method; Drug Resistance; Drug Therapy, Combination; Excitatory Amino Acid Antagonists; Female; Humans; Ketamine; Lithium Compounds; Male; Middle Aged; N-Methylaspartate; Placebos; Psychiatric Status Rating Scales; Treatment Outcome; Valproic Acid | 2010 |
Baseline delta sleep ratio predicts acute ketamine mood response in major depressive disorder.
Topics: Adolescent; Adult; Affect; Aged; Antidepressive Agents; Biomarkers; Depressive Disorder, Major; Drug Resistance; Electroencephalography; Excitatory Amino Acid Antagonists; Female; Humans; Ketamine; Male; Middle Aged; N-Methylaspartate; Psychiatric Status Rating Scales; Sleep; Young Adult | 2013 |
Shank3 as a potential biomarker of antidepressant response to ketamine and its neural correlates in bipolar depression.
Topics: Adult; Aged; Amygdala; Antidepressive Agents; Biomarkers; Bipolar Disorder; Double-Blind Method; Female; Humans; Ketamine; Male; N-Methylaspartate; Receptors, N-Methyl-D-Aspartate; Treatment Outcome | 2015 |
Glutamatergic Signaling Drives Ketamine-Mediated Response in Depression: Evidence from Dynamic Causal Modeling.
Topics: Adolescent; Adult; Affect; Aged; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Antidepressive Agents; Brain; Cross-Over Studies; Depressive Disorder, Major; Double-Blind Method; Evoked Potentials, Somatosensory; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Humans; Infusions, Intravenous; Ketamine; Magnetoencephalography; Male; Middle Aged; Models, Neurological; N-Methylaspartate; Time Factors; Treatment Outcome; Young Adult | 2018 |
Effect of different doses of esketamine compared with fentanyl combined with propofol on hypotension in patients undergoing painless abortion surgery: a prospective, randomized, double-blind controlled clinical trial.
Topics: Analgesics; Anesthetics, Intravenous; Double-Blind Method; Female; Fentanyl; Humans; Hypotension; Ketamine; N-Methylaspartate; Pregnancy; Propofol; Prospective Studies; Receptors, N-Methyl-D-Aspartate | 2022 |
Trial protocol for a multicenter randomized controlled trial to assess the efficacy and safety of intravenous ketamine for chronic daily headaches: the "KetHead" trial.
Topics: Adult; Headache; Headache Disorders; Humans; Ketamine; Multicenter Studies as Topic; N-Methylaspartate; Quality of Life; Randomized Controlled Trials as Topic | 2023 |
Effects of NMDA-receptor blockade by ketamine on mentalizing and its neural correlates in humans: a randomized control trial.
Topics: Glutamates; Humans; Ketamine; Mentalization; N-Methylaspartate; Receptors, N-Methyl-D-Aspartate | 2023 |
209 other study(ies) available for n-methylaspartate and ketamine
| Article | Year |
|---|---|
Ketamine-induced anesthesia involves the N-methyl-D-aspartate receptor-channel complex in mice.
Topics: Amino Acids; Anesthesia, General; Animals; Brain; Drug Synergism; Ion Channels; Ketamine; Male; Mice; N-Methylaspartate; Receptors, N-Methyl-D-Aspartate; Reflex; Time Factors | 1992 |
Influence of ketamine on the spontaneous motility of chick embryos and its development.
Topics: Animals; Cell Movement; Chick Embryo; Dose-Response Relationship, Drug; Embryonic and Fetal Development; gamma-Aminobutyric Acid; Ketamine; N-Methylaspartate; Time Factors | 1992 |
Glutamate, NMDA and NMDA receptor antagonists: cardiovascular effects of intrathecal administration in the rat.
Topics: 2-Amino-5-phosphonovalerate; Analysis of Variance; Animals; Blood Pressure; Glutamates; Glutamic Acid; Heart Rate; Hexamethonium; Hexamethonium Compounds; Injections, Spinal; Ketamine; Male; N-Methylaspartate; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Spinal Cord; Time Factors | 1992 |
NMDA receptor antagonists block cardiovascular responses to intrathecal administration of D-baclofen in the rat.
Topics: 2-Amino-5-phosphonovalerate; Animals; Baclofen; Blood Pressure; Injections, Intravenous; Injections, Spinal; Ketamine; Male; N-Methylaspartate; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Thoracic Vertebrae | 1992 |
Glycine is required for NMDA receptor activation: electrophysiological evidence from intact rat hippocampus.
Topics: Animals; Dizocilpine Maleate; Electric Stimulation; Electrophysiology; Evoked Potentials; Glycine; Hippocampus; Iontophoresis; Ketamine; Kynurenic Acid; Magnesium; Male; N-Methylaspartate; Rats; Receptors, N-Methyl-D-Aspartate; Time Factors | 1992 |
Ketamine decreases plasma catecholamines and improves outcome from incomplete cerebral ischemia in rats.
Topics: Animals; Blood Glucose; Blood Pressure; Brain; Brain Ischemia; Cerebrovascular Circulation; Electroencephalography; Epinephrine; Fentanyl; Ketamine; Male; N-Methylaspartate; Norepinephrine; Oxygen Consumption; Quinoxalines; Rats; Rats, Inbred Strains | 1992 |
Differential inhibition by NMDA antagonists of rapid tolerance to, and cross-tolerance between, ethanol and chlordiazepoxide.
Topics: Animals; Chlordiazepoxide; Dizocilpine Maleate; Drug Tolerance; Ethanol; Ketamine; Male; N-Methylaspartate; Rats; Rats, Inbred Strains; Time Factors | 1992 |
Dextromethorphan and phencyclidine receptor ligands: differential effects on K(+)- and NMDA-evoked increases in cytosolic free Ca2+ concentration.
Topics: Animals; Calcium; Cyclopentanes; Cytosol; Dextromethorphan; Female; Fura-2; Hippocampus; Ketamine; Ligands; N-Methylaspartate; Parasympatholytics; Potassium; Pregnancy; Pyramidal Tracts; Rats; Receptors, Neurotransmitter; Receptors, Phencyclidine | 1991 |
Characteristics of NMDA receptors that stimulate release of hypothalamic alpha-MSH.
Topics: alpha-MSH; Animals; Hypothalamus; In Vitro Techniques; Ketamine; Kinetics; Kynurenic Acid; Magnesium; Male; N-Methylaspartate; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Serine | 1991 |
Non-competitive NMDA-receptor antagonists and anoxic degeneration of the ERG B-wave in vitro.
Topics: Animals; Dextromethorphan; Dizocilpine Maleate; Electroretinography; Female; In Vitro Techniques; Ketamine; N-Methylaspartate; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Retina; Synaptic Transmission; Time Factors | 1991 |
Synergistic interactions between muscarinic antagonists, adrenergic agonists and NMDA antagonists with respect to locomotor stimulatory effects in monoamine-depleted mice.
Topics: Adrenergic alpha-Agonists; Animals; Atropine; Biperiden; Clonidine; Disease Models, Animal; Dizocilpine Maleate; Drug Synergism; Ketamine; Male; Methyldopa; Mice; Mice, Neurologic Mutants; Motor Activity; N-Methylaspartate; Parasympatholytics; Parkinson Disease; Piperazines | 1991 |
Similar behavioural effects of sigma agonists and PCP-like non-competitive NMDA antagonists in guinea-pigs.
Topics: Animals; Antipsychotic Agents; Behavior, Animal; Benzamides; Dizocilpine Maleate; Dopamine Agents; Dopamine Antagonists; Ergolines; Female; Guanidines; Guinea Pigs; Haloperidol; Ketamine; Male; Motor Activity; N-Methylaspartate; Pentazocine; Phenazocine; Phencyclidine; Quinpirole; Receptors, Dopamine D2; Receptors, Opioid; Receptors, sigma; Remoxipride | 1991 |
Effects of urethane and ketamine on substance P- and excitatory amino acid-induced behavior in mice.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Behavior, Animal; Injections, Spinal; Isomerism; Kainic Acid; Ketamine; Male; Mice; N-Methylaspartate; Quisqualic Acid; Substance P; Urethane | 1990 |
Antagonists at the NMDA recognition site and blockers of the associated ion channel induce spontaneous tail-flicks in the rat.
Topics: Animals; Behavior, Animal; Dizocilpine Maleate; Dose-Response Relationship, Drug; Ion Channels; Ketamine; Male; N-Methylaspartate; Organophosphorus Compounds; Phencyclidine; Pipecolic Acids; Piperazines; Piperidines; Pyrrolidinones; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate | 1991 |
Desmethylimipramine potentiates NMDA responses in a mouse cortical slice preparation.
Topics: Action Potentials; Animals; Anticonvulsants; Cerebral Cortex; Convulsants; Corpus Callosum; Desipramine; Epilepsy; Female; Ion Channels; Ketamine; Magnesium; Male; Mice; Mice, Inbred DBA; N-Methylaspartate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Receptors, Phencyclidine; Stimulation, Chemical | 1991 |
Effects of NMDA and calcium channel antagonists on regional cerebral blood flow.
Topics: Animals; Blood Pressure; Calcium Channel Blockers; Cerebral Cortex; Cerebrovascular Circulation; Dextromethorphan; Dextrorphan; Dizocilpine Maleate; Heart Rate; Ketamine; Mesencephalon; N-Methylaspartate; Nimodipine; Rabbits; Reference Values; Regional Blood Flow; Rhombencephalon | 1991 |
Effect of NMDA-receptor ligands on neocortical and hippocampal EEG activity of rat brain.
Topics: Animals; Cerebral Cortex; Dizocilpine Maleate; Electroencephalography; Hippocampus; Ketamine; Ligands; Male; N-Methylaspartate; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate | 1991 |
Dizocilpine, ketamine and ethanol reverse NMDA-induced EEG changes and convulsions in rats and mice.
Topics: Animals; Cerebral Cortex; Dizocilpine Maleate; Electroencephalography; Ethanol; Ketamine; Male; Mice; N-Methylaspartate; Rats; Receptors, N-Methyl-D-Aspartate; Seizures | 1991 |
The glycine site modulates NMDA-mediated changes of intracellular free calcium in cultures of hippocampal neurons.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Calcium; Cells, Cultured; Embryo, Mammalian; Glycine; Hippocampus; Ketamine; Kinetics; Kynurenic Acid; Macromolecular Substances; N-Methylaspartate; Neurons; Rats; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Serine | 1990 |
Mechanisms generating the time course of dual component excitatory synaptic currents recorded in hippocampal slices.
Topics: Animals; Aspartic Acid; Dibenzocycloheptenes; Dizocilpine Maleate; Electrophysiology; Glutamates; Glutamic Acid; Hippocampus; In Vitro Techniques; Kainic Acid; Ketamine; N-Methylaspartate; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Synapses; Temperature; Time Factors | 1990 |
Differentiation of the active site of minaprine from that of phencyclidine in rat hippocampus.
Topics: 2-Amino-5-phosphonovalerate; Acetylcholine; Animals; Binding Sites; Hippocampus; Ketamine; Male; Membranes; N-Methylaspartate; Phencyclidine; Piperazines; Piperidines; Potassium Channels; Pyridazines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate | 1990 |
Effects of NMDA antagonists on developmental plasticity in kitten visual cortex.
Topics: 2-Amino-5-phosphonovalerate; Anesthetics; Animals; Animals, Newborn; Cats; Cerebral Cortex; Dizocilpine Maleate; Injections; Ketamine; N-Methylaspartate; Neuronal Plasticity; Visual Cortex | 1990 |
Quisqualate-induced changes in extracellular sodium and calcium concentrations persist in the combined presence of NMDA and non-NMDA receptor antagonists in rat hippocampal slices.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Evoked Potentials; Extracellular Space; Glutamates; Glutamic Acid; Hippocampus; Ibotenic Acid; In Vitro Techniques; Ketamine; Membrane Potentials; N-Methylaspartate; Quinoxalines; Quisqualic Acid; Rats; Receptors, N-Methyl-D-Aspartate; Sodium | 1990 |
Swallowing responses induced by microinjection of glutamate and glutamate agonists into the nucleus tractus solitarius of ketamine-anesthetized rats.
Topics: Animals; Deglutition; Glutamates; Glutamic Acid; Ketamine; Medulla Oblongata; Microinjections; N-Methylaspartate; Quisqualic Acid; Rats; Rats, Inbred Strains | 1990 |
NMDA antagonists prevent hypothermic injury and death of mammalian spinal neurons.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cell Survival; Dizocilpine Maleate; Female; Freezing; Hypothermia, Induced; Ketamine; Mice; N-Methylaspartate; Neurons; Pregnancy; Spinal Cord Injuries | 1990 |
Protection by ethanol of cortical neurons from N-methyl-D-aspartate-induced neurotoxicity is associated with blocking calcium influx.
Topics: 2-Amino-5-phosphonovalerate; Animals; Calcium; Calcium Channel Blockers; Cell Survival; Cells, Cultured; Cerebral Cortex; Ethanol; Female; Ketamine; L-Lactate Dehydrogenase; N-Methylaspartate; Nervous System Diseases; Neurons; Pregnancy; Rats | 1990 |
Ketamine promotes hippocampal CA1 pyramidal neuron loss after a short-duration ischemic insult in rats.
Topics: Animals; Blood Pressure; Cell Survival; Hippocampus; Ischemic Attack, Transient; Ketamine; N-Methylaspartate; Neurons; Pyramidal Tracts; Rats; Rats, Inbred Strains | 1991 |
Changes in seizure activity of the neocortex during the early postnatal development of the rat: an electrophysiological study on slices in Mg(2+)-free medium.
Topics: Aging; Animals; Cerebral Cortex; Culture Media; Electrodes; Electrophysiology; In Vitro Techniques; Ketamine; Magnesium; N-Methylaspartate; Perfusion; Rats; Seizures; Somatosensory Cortex | 1991 |
Pneumotaxic mechanisms in the non-human primate: effect of the N-methyl-D-aspartate (NMDA) antagonist ketamine.
Topics: Anesthesia; Animals; Female; Halothane; Ketamine; Macaca fascicularis; Motor Neurons; N-Methylaspartate; Pentobarbital; Respiration | 1990 |
Interfering with glutamatergic neurotransmission by means of NMDA antagonist administration discloses the locomotor stimulatory potential of other transmitter systems.
Topics: Animals; Aspartic Acid; Atropine; Biogenic Monoamines; Clonidine; Dibenzocycloheptenes; Dizocilpine Maleate; Drug Synergism; Glutamates; Ketamine; Male; Mice; Motor Activity; N-Methylaspartate; Rats; Rats, Inbred Strains; Synaptic Transmission | 1990 |
N-methyl-D-aspartate receptor activation and Ca2+ account for poor pyramidal cell structure in hippocampal slices.
Topics: Adenosine Triphosphate; Amino Acids; Animals; Aspartic Acid; Buffers; Cell Nucleus; Cytoplasm; Cytoskeleton; Endoplasmic Reticulum; Guinea Pigs; Hippocampus; Ketamine; Magnesium; Microscopy, Electron; Mitochondria; N-Methylaspartate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1990 |
The noncompetitive N-methyl-D-aspartate antagonists, MK-801, phencyclidine and ketamine, increase the potency of general anesthetics.
Topics: Anesthesia, General; Anesthetics; Animals; Aspartic Acid; Behavior, Animal; Dibenzocycloheptenes; Dizocilpine Maleate; Drug Synergism; Ketamine; Male; Mice; Mice, Inbred ICR; N-Methylaspartate; Phencyclidine | 1990 |
Analgesic, anesthetic, and respiratory effects of the competitive N-methyl-D-aspartate (NMDA) antagonist CGS 19755 in rhesus monkeys.
Topics: Analgesics; Anesthetics; Animals; Binding, Competitive; Dose-Response Relationship, Drug; Ketamine; Macaca mulatta; N-Methylaspartate; Pipecolic Acids; Piperidines; Reaction Time; Respiration; Video Recording | 1990 |
Use-dependent block of excitatory amino acid currents in cultured neurons by ketamine.
Topics: Amino Acids; Animals; Aspartic Acid; Cells, Cultured; Electric Conductivity; Glutamates; Glutamic Acid; Hippocampus; Ion Channels; Kainic Acid; Ketamine; Membrane Potentials; Mice; N-Methylaspartate; Spinal Cord | 1987 |
Noncompetitive N-methyl-D-aspartate antagonists affect multiple ionic currents.
Topics: Action Potentials; Animals; Aspartic Acid; Dibenzocycloheptenes; Dizocilpine Maleate; Hippocampus; Ion Channels; Ketamine; N-Methylaspartate; Phencyclidine; Potassium; Rats; Receptors, AMPA; Receptors, Drug; Receptors, Kainic Acid; Receptors, Neurotransmitter | 1988 |
NMDA receptor antagonists that bind to the strychnine-insensitive glycine site and inhibit NMDA-induced Ca2+ fluxes and [3H]GABA release.
Topics: Animals; Anticonvulsants; Aspartic Acid; Brain; Calcium; Desipramine; Dibenzocycloheptenes; Dizocilpine Maleate; gamma-Aminobutyric Acid; Ketamine; Kynurenine; Membranes; N-Methylaspartate; Piperazines; Pyrrolidinones; Radioligand Assay; Rats; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Strychnine | 1989 |
NMDA-coupled and uncoupled forms of the PCP receptor: preliminary in vivo evidence for PCP receptor subtypes.
Topics: Animals; Aspartic Acid; Cerebellum; Cyclic GMP; Harmaline; Ketamine; Male; N-Methylaspartate; Phencyclidine; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Receptors, Phencyclidine; Reference Values | 1989 |
The behavioural effects of MK-801: a comparison with antagonists acting non-competitively and competitively at the NMDA receptor.
Topics: Animals; Anticonvulsants; Aspartic Acid; Behavior, Animal; Binding, Competitive; Dibenzocycloheptenes; Discrimination Learning; Dizocilpine Maleate; Dose-Response Relationship, Drug; Ketamine; Male; Motor Activity; N-Methylaspartate; Phenazocine; Phencyclidine; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Seizures | 1989 |
The effect of MK-801 and other antagonists of NMDA-type glutamate receptors on brain-stimulation reward.
Topics: Animals; Anticonvulsants; Aspartic Acid; Brain; Dibenzocycloheptenes; Dizocilpine Maleate; Dose-Response Relationship, Drug; Ketamine; Kynurenic Acid; Male; N-Methylaspartate; Rats; Receptors, Glutamate; Receptors, Neurotransmitter; Self Stimulation | 1989 |
Effects of pentobarbitone, ketamine and lignocaine on synaptic transmission in the rat olfactory cortex in vitro.
Topics: Action Potentials; Animals; Aspartic Acid; Cerebral Cortex; Depression, Chemical; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; In Vitro Techniques; Ketamine; Lidocaine; Male; N-Methylaspartate; Olfactory Pathways; Oxadiazoles; Pentobarbital; Quisqualic Acid; Rats; Rats, Inbred Strains; Synapses; Synaptic Transmission | 1989 |
Ifenprodil is a novel type of N-methyl-D-aspartate receptor antagonist: interaction with polyamines.
Topics: Acetamides; Animals; Aspartic Acid; Brain; Calcium; Cell Membrane; Dibenzocycloheptenes; Dizocilpine Maleate; Dose-Response Relationship, Drug; Glutamates; Glycine; In Vitro Techniques; Ketamine; Kinetics; N-Methylaspartate; Phencyclidine; Piperidines; Polyamines; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1989 |
Bursting induces persistent all-or-none EPSPs by an NMDA-dependent process in piriform cortex.
Topics: 2-Amino-5-phosphonovalerate; 4-Aminopyridine; Aminopyridines; Animals; Aspartic Acid; Cerebral Cortex; Chlorides; In Vitro Techniques; Ketamine; Magnesium; Membrane Potentials; N-Methylaspartate; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Synapses; Time Factors; Valine | 1989 |
NMDA antagonists and potentiation of NMDA-induced motoneuron depolarizations in the isolated frog spinal cord.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Cell Membrane; Dibenzocycloheptenes; Dizocilpine Maleate; Drug Synergism; Evoked Potentials; Ketamine; Kynurenic Acid; Magnesium; Motor Neurons; N-Methylaspartate; Potassium; Rana pipiens; Spinal Cord; Valine | 1989 |
The mechanism of action and pharmacological specificity of the anticonvulsant NMDA antagonist MK-801: a voltage clamp study on neuronal cells in culture.
Topics: Acetylcholine; Animals; Anticonvulsants; Aspartic Acid; Cells, Cultured; Dibenzocycloheptenes; Dizocilpine Maleate; Electric Stimulation; Evoked Potentials; Hippocampus; Ketamine; N-Methylaspartate; Neurons; Rats; Rats, Inbred Strains; Receptors, Serotonin | 1989 |
The competitive N-methyl-D-aspartate (NMDA) antagonist CGS 19755 attenuates the rate-decreasing effects of NMDA in rhesus monkeys without producing ketamine-like discriminative stimulus effects.
Topics: Animals; Anticonvulsants; Aspartic Acid; Dibenzocycloheptenes; Discrimination, Psychological; Dizocilpine Maleate; Ketamine; Macaca mulatta; Male; N-Methylaspartate; Pipecolic Acids; Piperidines | 1989 |
Quantitative assessment of neuroprotection against NMDA-induced brain injury.
Topics: Animals; Aspartic Acid; Brain; Brain Diseases; Choline O-Acetyltransferase; Corpus Striatum; Dibenzocycloheptenes; Dizocilpine Maleate; Dose-Response Relationship, Drug; Female; Ketamine; Male; N-Methylaspartate; Piperazines; Rats; Rats, Inbred Strains; Regression Analysis | 1989 |
The role of N-methylaspartate receptors in mediating responses of rat and cat spinal neurones to defined sensory stimuli.
Topics: Action Potentials; Animals; Anticonvulsants; Aspartic Acid; Cats; Female; Interneurons; Ketamine; Male; Methohexital; Motor Neurons; N-Methylaspartate; Neurons; Pipecolic Acids; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Reflex, Monosynaptic; Spinal Cord | 1987 |
A comparison of PCP-like compounds for NMDA antagonism in two in vivo models.
Topics: Animals; Aspartic Acid; Behavior, Animal; Dioxolanes; Dioxoles; Ketamine; Male; Mice; Motor Activity; N-Methylaspartate; Piperidines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Seizures | 1988 |
Differences in results from in vivo and in vitro studies on the use-dependency of N-methylaspartate antagonism by MK-801 and other phencyclidine receptor ligands.
Topics: Animals; Aspartic Acid; Cerebral Cortex; Dibenzocycloheptenes; Dizocilpine Maleate; In Vitro Techniques; Ketamine; N-Methylaspartate; Phencyclidine; Rats; Receptors, Neurotransmitter; Receptors, Phencyclidine; Spinal Cord; Substance-Related Disorders | 1988 |
N-methyl-D-aspartate (NMDA) receptors control respiratory off-switch in cat.
Topics: Action Potentials; Animals; Aspartic Acid; Cats; Dibenzocycloheptenes; Dizocilpine Maleate; Iontophoresis; Ketamine; N-Methylaspartate; Oxadiazoles; Phencyclidine; Phrenic Nerve; Quisqualic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Respiration; Respiratory Center | 1988 |
MK-801, a proposed noncompetitive antagonist of excitatory amino acid neurotransmission, produces phencyclidine-like behavioral effects in pigeons, rats and rhesus monkeys.
Topics: Anesthesia; Animals; Anticonvulsants; Aspartic Acid; Behavior, Animal; Catalepsy; Columbidae; Dibenzocycloheptenes; Discrimination Learning; Dizocilpine Maleate; Ketamine; Macaca mulatta; Male; N-Methylaspartate; Phencyclidine; Rats; Rats, Inbred Strains; Self Administration; Synaptic Transmission | 1988 |
Evidence for a role of the N-methyl-D-aspartate (NMDA) receptor in cortical spreading depression in the rat.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Aspartic Acid; Cortical Spreading Depression; Diazepam; Dibenzocycloheptenes; Dizocilpine Maleate; Ketamine; Male; N-Methylaspartate; Phencyclidine; Phenytoin; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1988 |
Phencyclidine receptors and N-methyl-D-aspartate antagonism: electrophysiologic data correlates with known behaviours.
Topics: Anesthetics, Dissociative; Animals; Anura; Aspartic Acid; Brain; Dose-Response Relationship, Drug; Electrophysiology; Ketamine; N-Methylaspartate; Phencyclidine; Rats; Rats, Inbred Strains; Receptors, Neurotransmitter; Receptors, Opioid; Receptors, Phencyclidine; Receptors, sigma; Spinal Cord | 1988 |
Quantitative studies on some antagonists of N-methyl D-aspartate in slices of rat cerebral cortex.
Topics: Animals; Aspartic Acid; Cerebral Cortex; Corpus Callosum; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; In Vitro Techniques; Kainic Acid; Ketamine; Male; Muscimol; N-Methylaspartate; Neuromuscular Depolarizing Agents; Neurons; Oxadiazoles; Potassium; Quisqualic Acid; Rats; Rats, Inbred Strains; Tetrodotoxin | 1985 |
Antagonism of N-methyl-D-aspartate-induced transmitter release in the rat striatum by phencyclidine-like drugs and its relationship to turning behavior.
Topics: Acetylcholine; Amphetamine; Animals; Apomorphine; Aspartic Acid; Benzomorphans; Chlorpromazine; Clozapine; Corpus Striatum; Cyclazocine; Dioxolanes; Dopamine; Haloperidol; Ketamine; Male; Mathematics; Motor Activity; N-Methylaspartate; Phencyclidine; Posture; Rats; Rats, Inbred Strains; Substantia Nigra | 1985 |
Ketamine acts as a non-competitive N-methyl-D-aspartate antagonist on frog spinal cord in vitro.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Kainic Acid; Ketamine; Magnesium; Motor Neurons; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Rana pipiens; Rana temporaria; Spinal Cord; Valine | 1985 |
Excitatory amino acids and regenerative activity in cultured neurons.
Topics: Animals; Aspartic Acid; Cells, Cultured; Electric Conductivity; Ketamine; Membrane Potentials; N-Methylaspartate; Neurons; Neurotransmitter Agents; Phencyclidine; Spinal Cord | 1986 |
Biphasic effect of quinolinate on frog spinal, but not rat cortical, neurones: N-methyl-D-aspartate-like depolarisation and a novel type of hyperpolarisation.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anterior Horn Cells; Anura; Aspartic Acid; Drug Interactions; Gyrus Cinguli; Kainic Acid; Ketamine; Magnesium; Membrane Potentials; Motor Neurons; N-Methylaspartate; Pyridines; Quinolinic Acid; Quinolinic Acids; Rats; Valine | 1987 |
Effects of ketamine on the in vivo toxicity of quinolinate and N-methyl-D-aspartate in the rat hippocampus.
Topics: 2-Amino-5-phosphonovalerate; Anesthesia, General; Animals; Aspartic Acid; Drug Interactions; Female; Halothane; Hippocampus; Ketamine; N-Methylaspartate; Pentobarbital; Pyridines; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains; Valine | 1987 |
Effects of ketamine and (+)cyclazocine on 4-aminopyridine and "magnesium free" epileptogenic activity in hippocampal slices of rats.
Topics: 2-Amino-5-phosphonovalerate; 4-Aminopyridine; Aminopyridines; Animals; Aspartic Acid; Cyclazocine; Epilepsy; Hippocampus; Ketamine; Magnesium; Male; N-Methylaspartate; Rats; Rats, Inbred Strains; Synaptic Transmission; Valine | 1987 |
Epileptiform activity induced by alkalosis in rat neocortical slices: block by antagonists of N-methyl-D-aspartate.
Topics: 2-Amino-5-phosphonovalerate; Alkalosis; Animals; Aspartic Acid; Cerebral Cortex; Epilepsy; In Vitro Techniques; Ketamine; Magnesium Deficiency; N-Methylaspartate; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine | 1987 |
Quinoxalinediones: potent competitive non-NMDA glutamate receptor antagonists.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Binding, Competitive; Cell Membrane; Cerebral Cortex; Ibotenic Acid; Kainic Acid; Ketamine; N-Methylaspartate; Neurons; Piperazines; Quinoxalines; Rats; Receptors, AMPA; Receptors, Drug; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Spinal Cord | 1988 |
Differential effects of N-methyl-D-aspartic acid and L-homocysteic acid on cerebellar Purkinje neurons.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Amino Acids; Animals; Aspartic Acid; Dipeptides; Glutamates; Homocysteine; Iontophoresis; Ketamine; Male; N-Methylaspartate; Purkinje Cells; Rats; Rats, Inbred Strains; Valine | 1988 |
Sites of antagonist action on N-methyl-D-aspartic acid receptors studied using fluctuation analysis and a rapid perfusion technique.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Binding Sites; Binding, Competitive; Cations, Divalent; Cells, Cultured; Glycine; Hippocampus; Ketamine; Kynurenic Acid; Magnesium; Mice; Mice, Inbred C57BL; N-Methylaspartate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine; Zinc | 1988 |
Differential effects of dextrorphan and levorphanol on the excitation of rat spinal neurons by amino acids.
Topics: Acetylcholine; Amino Acids; Animals; Aspartic Acid; Dextrorphan; Ketamine; Levorphanol; Morphinans; N-Methylaspartate; Neurons; Phencyclidine; Rats; Receptors, Opioid; Receptors, sigma; Spinal Cord | 1985 |
Is Metaphit a phencyclidine antagonist? Studies with ketamine, phencyclidine and N-methylaspartate.
Topics: Action Potentials; Animals; Aspartic Acid; Depression, Chemical; Drug Interactions; Kainic Acid; Ketamine; N-Methylaspartate; Neurons; Oxadiazoles; Phencyclidine; Quisqualic Acid; Rats; Receptors, Opioid; Receptors, sigma; Spinal Cord | 1986 |
Antagonism of N-methylaspartate and synaptic responses of neurones in the rat ventrobasal thalamus by ketamine and MK-801.
Topics: Animals; Anticonvulsants; Aspartic Acid; Dibenzocycloheptenes; Dizocilpine Maleate; Female; Ketamine; Male; N-Methylaspartate; Rats; Synapses; Thalamus | 1988 |
Characterization of motor activity patterns induced by N-methyl-D-aspartate antagonists in gerbils.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Dose-Response Relationship, Drug; Electronic Data Processing; Female; Gerbillinae; Ketamine; Motor Activity; N-Methylaspartate; Pipecolic Acids; Piperazines; Piperidines; Time Factors | 1987 |
2-Methyl-3,3-diphenyl-3-propanolamine (2-MDP) selectively antagonises N-methyl-aspartate (NMA).
Topics: Anesthetics; Anesthetics, Dissociative; Animals; Anura; Aspartic Acid; In Vitro Techniques; Kainic Acid; Ketamine; Medulla Oblongata; N-Methylaspartate; Neurons; Oxadiazoles; Phenylpropanolamine; Quisqualic Acid; Rats; Spinal Cord | 1986 |
The anticonvulsant MK-801 is a potent N-methyl-D-aspartate antagonist.
Topics: Animals; Anticonvulsants; Aspartic Acid; Binding Sites; Brain; Dibenzocycloheptenes; Dizocilpine Maleate; In Vitro Techniques; Ketamine; Male; N-Methylaspartate; Phenazocine; Phencyclidine; Rats; Rats, Inbred Strains | 1986 |
Ketamine selectively suppresses synchronized afterdischarges in immature hippocampus.
Topics: Aging; Animals; Aspartic Acid; Evoked Potentials; Hippocampus; Iontophoresis; Ketamine; Membrane Potentials; N-Methylaspartate; Neural Inhibition; Neurons; Penicillins; Rats | 1986 |
Effect of ketamine on amino acid-evoked release of acetylcholine from rat cerebral cortex in vitro.
Topics: Acetylcholine; Amino Acids; Animals; Aspartic Acid; Brain Chemistry; Cerebral Cortex; Dose-Response Relationship, Drug; In Vitro Techniques; Kainic Acid; Ketamine; Magnesium; N-Methylaspartate; Potassium Chloride; Rats | 1985 |
An intracellular study of the interactions of N-methyl-DL-aspartate with ketamine in the mouse hippocampal slice.
Topics: Action Potentials; Animals; Aspartic Acid; Drug Interactions; Hippocampus; In Vitro Techniques; Kainic Acid; Ketamine; Membrane Potentials; Mice; Mice, Inbred C57BL; N-Methylaspartate; Oxadiazoles; Quisqualic Acid | 1985 |
Comparison of sigma- and kappa-opiate receptor ligands as excitatory amino acid antagonists.
Topics: Acetylcholine; Amino Acids; Animals; Aspartic Acid; Cats; Cyclazocine; Ethylketocyclazocine; Kainic Acid; Ketamine; Ligands; Microelectrodes; N-Methylaspartate; Neurons; Oxadiazoles; Phenazocine; Quisqualic Acid; Rats; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, sigma; Stereoisomerism | 1984 |
The effect of the dioxolanes on amino acid induced excitation in the mammalian spinal cord.
Topics: Animals; Aspartic Acid; Cats; Dioxolanes; Dioxoles; Kainic Acid; Ketamine; N-Methylaspartate; Oxadiazoles; Phencyclidine; Quisqualic Acid; Rats; Species Specificity; Spinal Cord; Stereoisomerism; Structure-Activity Relationship | 1984 |
The dissociative anaesthetics, ketamine and phencyclidine, selectively reduce excitation of central mammalian neurones by N-methyl-aspartate.
Topics: Acetylcholine; Animals; Aspartic Acid; Cats; Female; In Vitro Techniques; Ketamine; Male; N-Methylaspartate; Neurons; Phencyclidine; Rats; Receptors, Cell Surface; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Synapses | 1983 |
Effects of optical isomers of ketamine on excitation of cat and rat spinal neurones by amino acids and acetylcholine.
Topics: Acetylcholine; Action Potentials; Animals; Aspartic Acid; Cats; Ketamine; N-Methylaspartate; Neurons; Rats; Spinal Cord; Stereoisomerism | 1982 |
In vivo characterization of two cell types in the rat globus pallidus which have opposite responses to dopamine receptor stimulation: comparison of electrophysiological properties and responses to apomorphine, dizocilpine, and ketamine anesthesia.
Topics: Anesthesia; Animals; Apomorphine; Dizocilpine Maleate; Dopamine Antagonists; Dose-Response Relationship, Drug; Electrophysiology; Globus Pallidus; Ketamine; Male; N-Methylaspartate; Rats; Rats, Sprague-Dawley; Receptors, Dopamine | 1995 |
Evaluation of the mechanisms underlying the kainate-induced impairment of [3H]dopamine release in the rat striatum.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Corpus Striatum; Dizocilpine Maleate; Dopamine; Electric Stimulation; Kainic Acid; Ketamine; Male; N-Methylaspartate; Neuromuscular Depolarizing Agents; Neurons, Afferent; Pipecolic Acids; Quinoxalines; Rats; Rats, Sprague-Dawley | 1993 |
The subthalamo-nigral pathway regulates movement and concomitant acetylcholinesterase release from the substantia nigra.
Topics: Acetylcholinesterase; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Dendrites; Electric Stimulation; Electrophysiology; Excitatory Amino Acid Agonists; Guinea Pigs; Ketamine; Male; Motor Activity; N-Methylaspartate; Neural Pathways; Substantia Nigra; Urethane | 1994 |
Influence of ketamine on the neuronal death caused by NMDA in the rat hippocampus.
Topics: Animals; Cell Death; Diazepam; Dizocilpine Maleate; Hippocampus; Ketamine; N-Methylaspartate; Neurons; Rats; Rats, Wistar | 1995 |
Block of the N-methyl-D-aspartate receptor by phencyclidine-like drugs is influenced by alternative splicing.
Topics: Alternative Splicing; Animals; Dizocilpine Maleate; Dose-Response Relationship, Drug; Gene Expression; Glycine; Ketamine; Kinetics; N-Methylaspartate; Oocytes; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Xenopus | 1995 |
NMDA-activated currents in Bergmann glial cells.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Calcium; Cell Membrane; Cerebellum; In Vitro Techniques; Ion Channels; Ketamine; Mice; N-Methylaspartate; Neuroglia; Neurons; Quinoxalines; Receptors, N-Methyl-D-Aspartate | 1993 |
Excitatory amino acid receptor mediation of sensory inputs to functionally identified dorsal horn neurons in cat spinal cord.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cats; Decerebrate State; Evoked Potentials; Glutamates; Glutamic Acid; Ibotenic Acid; Kainic Acid; Ketamine; Kynurenic Acid; N-Methylaspartate; Neurons; Quinoxalines; Quisqualic Acid; Receptors, Amino Acid; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Synapses | 1993 |
Ketamine inhibits glutamate-, N-methyl-D-aspartate-, and quisqualate-stimulated cGMP production in cultured cerebral neurons.
Topics: Animals; Brain; Cells, Cultured; Cyclic GMP; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glutamic Acid; Ketamine; N-Methylaspartate; Neurons; Nitric Oxide; Nitroprusside; Quisqualic Acid; Rats; Rats, Sprague-Dawley | 1995 |
N-methyl-D-aspartate (NMDA) stimulates release of alpha-MSH from the rat hypothalamus through release of nitric oxide.
Topics: 2-Amino-5-phosphonovalerate; alpha-MSH; Animals; Arginine; Hypothalamus; Ketamine; Male; N-Methylaspartate; NG-Nitroarginine Methyl Ester; Nitric Oxide; Potassium; Rats; Rats, Wistar | 1994 |
Synaptic excitation triggers oscillations during NMDA receptor activation in rat abducens motoneurons.
Topics: 2-Amino-5-phosphonovalerate; Abducens Nerve; Animals; Dizocilpine Maleate; Electrophysiology; Evoked Potentials; Glutamates; Glutamic Acid; Ketamine; Male; Motor Neurons; N-Methylaspartate; Oscillometry; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Synapses | 1993 |
NMDA antagonists increase recovery of evoked potentials from slices of rat olfactory cortex after anoxia.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cell Hypoxia; Dizocilpine Maleate; Evoked Potentials; Female; In Vitro Techniques; Ketamine; N-Methylaspartate; Olfactory Pathways; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 1994 |
Effect of NMDA antagonists on rapid and chronic tolerance to ethanol: importance of intoxicated practice.
Topics: Animals; Dizocilpine Maleate; Drug Tolerance; Ethanol; Ketamine; Learning; Male; N-Methylaspartate; Postural Balance; Psychomotor Performance; Rats; Rats, Sprague-Dawley | 1994 |
Effects of the NMDA receptor antagonist ketamine on flavor memory: conditioned aversion, latent inhibition, and habituation of neophobia.
Topics: Animals; Behavior, Animal; Conditioning, Psychological; Habituation, Psychophysiologic; Inhibition, Psychological; Ketamine; Male; Memory; N-Methylaspartate; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Taste | 1994 |
Glutamate metabotropic receptor mediated depression of synaptic inputs to lamprey reticulospinal neurones.
Topics: 2-Amino-5-phosphonovalerate; Animals; Axons; Cycloleucine; Electric Stimulation; Electrophysiology; Evoked Potentials; GTP-Binding Proteins; Ketamine; Lampreys; Microelectrodes; N-Methylaspartate; Neurons; Receptors, Glutamate; Reticular Formation; Rhombencephalon; Spinal Cord; Synapses | 1993 |
Patch clamp studies on the kinetics and selectivity of N-methyl-D-aspartate receptor antagonism by memantine (1-amino-3,5-dimethyladamantan).
Topics: Animals; Cells, Cultured; Dextrorphan; Dizocilpine Maleate; Dose-Response Relationship, Drug; Embryo, Mammalian; gamma-Aminobutyric Acid; Glycine; Hippocampus; Ketamine; Kinetics; Magnesium; Memantine; Membrane Potentials; N-Methylaspartate; Neurons; Phencyclidine; Rats; Receptors, N-Methyl-D-Aspartate; Superior Colliculi | 1993 |
Thyrotropin-releasing hormone (TRH)-induced facilitation of spinal neurotransmission: a role for NMDA receptors.
Topics: Action Potentials; Animals; Electric Stimulation; Ketamine; Male; Motor Neurons; Muscles; N-Methylaspartate; Nociceptors; Physical Stimulation; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Reflex; Spinal Cord; Synaptic Transmission; Thyrotropin-Releasing Hormone | 1994 |
Effect of ketamine-anesthesia on N-methyl-D-aspartate-induced activation of type I nucleus accumbens neurons.
Topics: Anesthesia; Animals; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Interactions; Electrophysiology; Iontophoresis; Ketamine; Male; N-Methylaspartate; Neurons; Nucleus Accumbens; Rats; Rats, Sprague-Dawley | 1994 |
High-dose ketamine does not induce c-Fos protein expression in rat hippocampus.
Topics: Amygdala; Animals; Behavior, Animal; Cerebral Cortex; Hippocampus; Immunohistochemistry; In Vitro Techniques; Kainic Acid; Ketamine; Male; N-Methylaspartate; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar; Seizures; Thalamus | 1993 |
Suppression of cortical epileptic afterdischarges by ketamine is not stable during ontogenesis in rats.
Topics: Animals; Anticonvulsants; Cerebral Cortex; Dose-Response Relationship, Drug; Electric Stimulation; Electrodes, Implanted; Electroencephalography; Epilepsy; Excitatory Amino Acid Antagonists; Female; Ketamine; Movement; N-Methylaspartate; Rats; Rats, Wistar | 1995 |
Ketamine antagonizes hypoxia-induced dopamine release in rat striatum.
Topics: Animals; Blood Gas Analysis; Dopamine; Dopamine Antagonists; Electrochemistry; Hydrogen-Ion Concentration; Hypercapnia; Hypoxia; Ketamine; Microinjections; N-Methylaspartate; Neostriatum; Nitrogen; Potassium Chloride; Rats; Rats, Sprague-Dawley; Respiration; Tubocurarine | 1995 |
Excitotoxic neurotoxicity in an in vitro brain slice model.
Topics: Animals; Apoptosis; Brain; Disease Models, Animal; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; In Vitro Techniques; Ketamine; Mice; N-Methylaspartate; Necrosis; Receptors, N-Methyl-D-Aspartate | 1995 |
N-methyl-D,L-aspartate-induced growth hormone secretion in barrows: possible mechanisms of action.
Topics: Animals; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Growth Hormone; Growth Hormone-Releasing Hormone; Immune Sera; Injections, Intravenous; Isomerism; Ketamine; Male; N-Methylaspartate; Receptors, N-Methyl-D-Aspartate; Swine | 1996 |
The role of excitatory amino acids in pulsatile secretion of luteinizing hormone in gilts and barrows.
Topics: Animals; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Amino Acids; Female; Hydrocortisone; Ketamine; Luteinizing Hormone; Male; N-Methylaspartate; Ovariectomy; Pituitary-Adrenal System; Swine | 1996 |
Thyrotropin-releasing hormone facilitates spinal nociceptive responses by potentiating NMDA receptor-mediated transmission.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analysis of Variance; Animals; Dose-Response Relationship, Drug; Drug Synergism; Excitatory Amino Acid Antagonists; Hot Temperature; Ketamine; Male; N-Methylaspartate; Pain Measurement; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Thyrotropin-Releasing Hormone | 1996 |
Halothane and diazepam inhibit ketamine-induced c-fos expression in the rat cingulate cortex.
Topics: Anesthetics, Inhalation; Animals; Diazepam; Drug Interactions; Excitatory Amino Acid Antagonists; GABA Modulators; Gene Expression; Genes, fos; Gyrus Cinguli; Halothane; Immunohistochemistry; Ketamine; Male; N-Methylaspartate; Rats; Rats, Wistar | 1996 |
Comparative patch-clamp studies with freshly dissociated rat hippocampal and striatal neurons on the NMDA receptor antagonistic effects of amantadine and memantine.
Topics: Amantadine; Animals; Dose-Response Relationship, Drug; Hippocampus; Ketamine; Memantine; Membrane Potentials; N-Methylaspartate; Patch-Clamp Techniques; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate | 1996 |
Effect of NMDA antagonists on rapid tolerance to benzodiazepines.
Topics: Animals; Chlordiazepoxide; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Tolerance; Ketamine; Male; N-Methylaspartate; Rats; Rats, Sprague-Dawley; Time Factors | 1997 |
Inhibition of nicotinic cholinoceptor mediated current in vagal motor neurons by local anesthetics.
Topics: Anesthetics, Local; Animals; Etidocaine; Ion Channel Gating; Ketamine; Male; Motor Neurons; N-Methylaspartate; Nicotinic Antagonists; Patch-Clamp Techniques; Procaine; Rats; Vagus Nerve | 1996 |
Activation of N-methyl-D-aspartate receptor attenuates acute responsiveness of delta-opioid receptors.
Topics: Analgesics; Animals; CHO Cells; Cricetinae; Cyclic AMP-Dependent Protein Kinases; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Glioma; Ketamine; Mice; N-Methylaspartate; Neuroblastoma; Neurons; Phosphorylation; Protein Kinase C; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid, delta; Signal Transduction | 1997 |
An abnormal ketamine response in mutants defective in the ryanodine receptor gene ryr-1 (unc-68) of Caenorhabditis elegans.
Topics: Amino Acid Sequence; Anesthetics, Dissociative; Animals; Animals, Genetically Modified; Aspartic Acid; Caenorhabditis elegans; Calcium Channels; Cloning, Molecular; Gene Expression; Genes, Helminth; Ketamine; Molecular Sequence Data; Muscle Contraction; Muscle Proteins; Mutation; N-Methylaspartate; Organ Specificity; Phosphorylation; Receptors, N-Methyl-D-Aspartate; Recombinant Fusion Proteins; Ryanodine Receptor Calcium Release Channel; Sequence Analysis, DNA; Sequence Homology, Amino Acid | 1997 |
The effects of NMDA on spontaneous motility and its development in chick embryos.
Topics: Animals; Chick Embryo; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Ketamine; Movement; N-Methylaspartate; Receptors, N-Methyl-D-Aspartate | 1996 |
Ethanol inhibition of N-methyl-D-aspartate-activated current in mouse hippocampal neurones: whole-cell patch-clamp analysis.
Topics: Animals; Cells, Cultured; Dose-Response Relationship, Drug; Ethanol; Hippocampus; Hydrogen-Ion Concentration; Ketamine; Magnesium; Membrane Potentials; Mice; N-Methylaspartate; Neurons; Oxidation-Reduction; Patch-Clamp Techniques; Spermine; Zinc | 1997 |
Effect of NMDA antagonists on development of rapid tolerance to various barbiturates.
Topics: Animals; Barbital; Barbiturates; Dizocilpine Maleate; Drug Tolerance; Ketamine; Male; N-Methylaspartate; Pentobarbital; Phenobarbital; Rats; Rats, Sprague-Dawley | 1998 |
Suppression of cyclic guanosine monophosphate formation in rat cerebellar slices by propofol, ketamine and midazolam.
Topics: Anesthetics, Intravenous; Animals; Cerebellum; Cyclic GMP; Depression, Chemical; Glutamic Acid; In Vitro Techniques; Ketamine; Midazolam; N-Methylaspartate; Nitroprusside; Propofol; Rats; Rats, Wistar; Vasodilator Agents | 1997 |
Tetrodotoxin inactivation of the gustatory cortex disrupts the effect of the N-methyl-D-aspartate antagonist ketamine on latent inhibition of conditioned taste aversion in rats.
Topics: Animals; Avoidance Learning; Cerebral Cortex; Conditioning, Psychological; Female; Injections, Intraperitoneal; Ketamine; Male; N-Methylaspartate; Rats; Rats, Inbred Strains; Taste; Tetrodotoxin | 1998 |
Embryonic development of spontaneous motility in chick embryos. Identification of participation of NMDA-mechanism by magnesium ions.
Topics: Animals; Chick Embryo; Excitatory Amino Acid Antagonists; Ketamine; Magnesium Chloride; Movement; N-Methylaspartate | 1997 |
Substitution of another opioid for morphine. Opioid toxicity should be managed initially by decreasing the opioid dose.
Topics: Analgesics, Opioid; Anesthetics, Dissociative; Humans; Ketamine; Morphine; N-Methylaspartate; Pain; Practice Guidelines as Topic | 1998 |
Substitution of another opioid for morphine. Methadone can be used to manage neuropathic pain related to cancer.
Topics: Analgesics, Opioid; Anesthetics, Dissociative; Humans; Ketamine; Methadone; N-Methylaspartate; Neoplasms; Pain | 1998 |
Differences in degree of trapping of low-affinity uncompetitive N-methyl-D-aspartic acid receptor antagonists with similar kinetics of block.
Topics: Animals; Cells, Cultured; Excitatory Amino Acid Antagonists; Ketamine; Kinetics; Memantine; Mice; Mice, Inbred BALB C; N-Methylaspartate; Neurons; Rats; Receptors, N-Methyl-D-Aspartate | 1999 |
The putative cognitive enhancer KA-672.HCl is an uncompetitive voltage-dependent NMDA receptor antagonist.
Topics: Animals; Benzopyrans; Cognition; Dose-Response Relationship, Drug; Electrophysiology; Excitatory Amino Acid Antagonists; Hippocampus; Ketamine; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Piperazines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate | 1998 |
Nitric oxide (NO) release by glutamate and NMDA in the dorsal horn of the spinal cord: an in vivo electrochemical approach in the rat.
Topics: Animals; Dizocilpine Maleate; Electrochemistry; Excitatory Amino Acid Antagonists; Glutamic Acid; Ketamine; Male; N-Methylaspartate; Nitric Oxide; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Spinal Cord | 1999 |
Gamma-aminobutyric acid and glutamic acid receptors may mediate theophylline-induced seizures in mice.
Topics: 2-Amino-5-phosphonovalerate; Aminobutyrates; Aminooxyacetic Acid; Animals; Baclofen; Bicuculline; Clonidine; Dextromethorphan; Drug Interactions; Female; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Ketamine; Mice; Muscimol; N-Methylaspartate; Picrotoxin; Receptors, GABA; Receptors, Glutamate; Seizures; Theophylline | 1999 |
Potentiation of DOM-induced stimulus control by non-competitive NMDA antagonists: a link between the glutamatergic and serotonergic hypotheses of schizophrenia.
Topics: Animals; Discrimination Learning; Disease Models, Animal; Dizocilpine Maleate; DOM 2,5-Dimethoxy-4-Methylamphetamine; Dose-Response Relationship, Drug; Drug Synergism; Excitatory Amino Acid Antagonists; Hallucinogens; Ketamine; Male; N-Methylaspartate; Phencyclidine; Rats; Rats, Inbred F344; Schizophrenia | 2000 |
The effect of ketamine hydrochloride anesthesia on basal and N-methyl-D,L-aspartate induced plasma prolactin secretion in the adult male rhesus monkey.
Topics: Anesthetics, Dissociative; Animals; Drug Administration Schedule; Drug Interactions; Excitatory Amino Acid Antagonists; Injections, Intramuscular; Ketamine; Macaca mulatta; Male; N-Methylaspartate; Prolactin; Receptors, N-Methyl-D-Aspartate; Stimulation, Chemical | 2001 |
Molecular modeling of noncompetitive antagonists of the NMDA receptor: proposal of a pharmacophore and a description of the interaction mode.
Topics: Binding Sites; Dioxolanes; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Ketamine; Lipids; Models, Molecular; Molecular Structure; N-Methylaspartate; Nitrogen; Phencyclidine; Piperidines; Quinolines; Receptors, N-Methyl-D-Aspartate; Static Electricity | 2002 |
Characterization of the discriminative stimulus effects of N-methyl- D-aspartate ligands under different ethanol training conditions in the cynomolgus monkey ( Macaca fascicularis).
Topics: Animals; Central Nervous System Depressants; Conditioning, Operant; Discrimination, Psychological; Dizocilpine Maleate; Dose-Response Relationship, Drug; Ethanol; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Ketamine; Macaca fascicularis; Male; N-Methylaspartate; Phencyclidine; Receptors, N-Methyl-D-Aspartate; Sex Factors | 2002 |
Effects of ketamine on leading saccades during smooth-pursuit eye movements may implicate cerebellar dysfunction in schizophrenia.
Topics: Adult; Cerebellum; Double-Blind Method; Female; Humans; Ketamine; Male; N-Methylaspartate; Placebos; Psychiatric Status Rating Scales; Pursuit, Smooth; Receptors, N-Methyl-D-Aspartate; Saccades; Schizophrenia; Synaptic Transmission | 2002 |
Ketamine and MK-801 decrease acetylcholine release in the pontine reticular formation, slow breathing, and disrupt sleep.
Topics: Acetylcholine; Animals; Cats; Chromatography, High Pressure Liquid; Dizocilpine Maleate; Electroencephalography; Electromyography; Electrooculography; Excitatory Amino Acid Antagonists; Ketamine; Male; N-Methylaspartate; Polysomnography; Pons; Respiration; Reticular Formation; Sleep Wake Disorders; Sleep, REM; Time Factors; Wakefulness | 2002 |
Ketamine impairs multiple cognitive domains in rhesus monkeys.
Topics: Anesthetics, Dissociative; Animals; Brain; Cognition; Dose-Response Relationship, Drug; Ketamine; Macaca mulatta; Male; Motor Skills; N-Methylaspartate; Neuropsychological Tests; Psychomotor Performance; Reaction Time; Task Performance and Analysis | 2002 |
Neuroprotective and neurotoxic properties of the 'inert' gas, xenon.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Biomarkers; Brain; Brain Injuries; Dizocilpine Maleate; Female; Gene Expression; Haloperidol; Ketamine; Models, Animal; N-Methylaspartate; Neuroprotective Agents; Nitrous Oxide; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Xenon | 2002 |
Interactions of NMDA antagonists and an alpha 2 agonist with mu, delta and kappa opioids in an acute nociception assay.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Adrenergic alpha-Agonists; Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Benzamides; Clonidine; Dextromethorphan; Dose-Response Relationship, Drug; Drug Synergism; Fentanyl; Ketamine; Male; Mice; Morphine; N-Methylaspartate; Pain; Pain Measurement; Piperazines; Reaction Time; Receptors, Opioid | 2002 |
Dendritic glutamate-induced bursting in the prefrontal cortex: further characterization and effects of phencyclidine.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Dendrites; Electrophysiology; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamates; Hallucinogens; Ketamine; Lysine; Male; Membrane Potentials; N-Methylaspartate; Phencyclidine; Prefrontal Cortex; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Synapses | 2003 |
Effects of ketamine and N-methyl-D-aspartate on glutamate and dopamine release in the rat prefrontal cortex: modulation by a group II selective metabotropic glutamate receptor agonist LY379268.
Topics: Amino Acids; Anesthetics, Local; Animals; Bridged Bicyclo Compounds, Heterocyclic; Dopamine; Drug Administration Routes; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Ketamine; Male; Microdialysis; N-Methylaspartate; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Tetrodotoxin; Time Factors | 2003 |
Modulation of growth hormone, luteinizing hormone, and testosterone secretion by excitatory amino acids in boars.
Topics: Animals; Excitatory Amino Acids; Growth Hormone; Ketamine; Luteinizing Hormone; Male; N-Methylaspartate; Receptors, N-Methyl-D-Aspartate; Swine; Testosterone | 2002 |
Hyperactivity following postnatal NMDA antagonist treatment: reversal by D-amphetamine.
Topics: Animals; Behavior, Animal; Brain; Central Nervous System Depressants; Central Nervous System Stimulants; Dextroamphetamine; Dizocilpine Maleate; Ethanol; Excitatory Amino Acid Antagonists; Female; Fluoresceins; Fluorescent Dyes; Habituation, Psychophysiologic; Hyperkinesis; Ketamine; Male; Mice; Motor Activity; N-Methylaspartate; Organic Chemicals; Pregnancy; Weight Gain | 2003 |
Extracellular taurine in the substantia nigra: taurine-glutamate interaction.
Topics: Adrenergic Agents; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Brain Chemistry; Calcium; Chelating Agents; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Drug Interactions; Egtazic Acid; Excitatory Amino Acid Antagonists; Extracellular Space; gamma-Aminobutyric Acid; Glutamic Acid; Kainic Acid; Ketamine; Male; Membrane Potentials; Microdialysis; N-Methylaspartate; Oxidopamine; Potassium; Rats; Rats, Sprague-Dawley; Substantia Nigra; Taurine; Time Factors; Zinc | 2004 |
The effects of ketamine vary among inbred mouse strains and mimic schizophrenia for the P80, but not P20 or N40 auditory ERP components.
Topics: Animals; Disease Models, Animal; Evoked Potentials, Auditory; Humans; Ketamine; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Inbred Strains; N-Methylaspartate; Schizophrenia; Species Specificity | 2004 |
Characterization of the non-competitive antagonist binding site of the NMDA receptor in dark Agouti rats.
Topics: Animals; Binding, Competitive; Brain; Dextromethorphan; Dioxolanes; Dizocilpine Maleate; Dose-Response Relationship, Drug; Female; Ketamine; N-Methylaspartate; Phenazocine; Phencyclidine; Piperidines; Rats; Rats, Mutant Strains; Receptors, N-Methyl-D-Aspartate; Scintillation Counting; Tritium | 2004 |
Diminished neuronal activity increases neuron-neuron connectivity underlying silent synapse formation and the rapid conversion of silent to functional synapses.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cell Count; Cells, Cultured; Dizocilpine Maleate; Dose-Response Relationship, Radiation; Drug Interactions; Electric Stimulation; Embryo, Mammalian; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamate Decarboxylase; Hippocampus; Immunohistochemistry; Isoenzymes; Ketamine; Membrane Potentials; N-Methylaspartate; Nerve Net; Neural Inhibition; Neurons; Patch-Clamp Techniques; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Sodium Channel Blockers; Statistics, Nonparametric; Synapses; Synaptic Transmission; Synaptophysin; Tetrodotoxin; Time Factors | 2005 |
Neuroprotective effects of preconditioning ischaemia on ischaemic brain injury through inhibition of mixed-lineage kinase 3 via NMDA receptor-mediated Akt1 activation.
Topics: Animals; Blotting, Western; Brain; Brain Ischemia; Cell Death; Chromones; Dimethyl Sulfoxide; Disease Models, Animal; Drug Interactions; Enzyme Activation; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Free Radical Scavengers; Ischemic Preconditioning; Ketamine; Male; MAP Kinase Kinase Kinases; Mitogen-Activated Protein Kinase Kinase Kinase 11; Mitogen-Activated Protein Kinase Kinases; Models, Biological; Morpholines; N-Methylaspartate; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Receptors, N-Methyl-D-Aspartate; Reperfusion; Time Factors | 2005 |
Discriminative stimulus effects of gamma-hydroxybutyrate (GHB) and its metabolic precursor, gamma-butyrolactone (GBL) in rats.
Topics: 4-Butyrolactone; Animals; Discrimination Learning; Dose-Response Relationship, Drug; Ethanol; Generalization, Stimulus; Illicit Drugs; Ketamine; Male; N-Methylaspartate; Phencyclidine; Rats; Rats, Sprague-Dawley; Sodium Oxybate | 2005 |
Ketamine-induced apoptosis in cultured rat cortical neurons.
Topics: Anesthetics, Dissociative; Animals; Apoptosis; Caspase 3; Caspases; Cell Survival; Cells, Cultured; Cerebral Cortex; Dizocilpine Maleate; Glycogen Synthase Kinase 3; Ketamine; N-Methylaspartate; Neurons; Phosphorylation; Proto-Oncogene Proteins c-akt; Rats; Rats, Wistar | 2006 |
A specific role for NR2A-containing NMDA receptors in the maintenance of parvalbumin and GAD67 immunoreactivity in cultured interneurons.
Topics: Animals; Calcium; Cells, Cultured; Cyclic AMP Response Element-Binding Protein; Excitatory Amino Acid Antagonists; Extracellular Signal-Regulated MAP Kinases; Glutamate Decarboxylase; Immunohistochemistry; Interneurons; Isoenzymes; Ketamine; Mice; N-Methylaspartate; Parvalbumins; Patch-Clamp Techniques; Phosphorylation; Prosencephalon; Receptors, N-Methyl-D-Aspartate | 2006 |
Minocycline protects PC12 cells against NMDA-induced injury via inhibiting 5-lipoxygenase activation.
Topics: Analysis of Variance; Animals; Arachidonate 5-Lipoxygenase; Blotting, Western; Calcium; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Activation; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Flavanones; Immunohistochemistry; Ketamine; Minocycline; N-Methylaspartate; Neuroprotective Agents; PC12 Cells; Rats; Tetrazolium Salts; Thiazoles; Time Factors | 2006 |
The antiallodynic effect of NMDA antagonists in neuropathic pain outlasts the duration of the in vivo NMDA antagonism.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analgesics, Opioid; Animals; Cold Temperature; Constriction, Pathologic; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Fentanyl; Iontophoresis; Ketamine; Male; Motor Activity; N-Methylaspartate; Pain; Peripheral Nervous System Diseases; Phthalazines; Posterior Horn Cells; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Spinal Cord | 2006 |
Sensitivity of rat temporalis muscle afferent fibers to peripheral N-methyl-D-aspartate receptor activation.
Topics: Afferent Pathways; Analysis of Variance; Animals; Blood Pressure; Electric Stimulation; Estrogens; Evoked Potentials; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Ketamine; Male; N-Methylaspartate; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, N-Methyl-D-Aspartate; Sensory Thresholds; Sex Factors; Temporal Muscle; Trigeminal Nerve | 2006 |
Ketamine and thiopental sodium: individual and combined neuroprotective effects on cortical cultures exposed to NMDA or nitric oxide.
Topics: Anesthetics, Dissociative; Anesthetics, Intravenous; Animals; Cell Survival; Cells, Cultured; Cerebral Cortex; Dose-Response Relationship, Drug; Drug Combinations; Ketamine; N-Methylaspartate; Neurons; Neuroprotective Agents; Rats; Rats, Wistar; Thiopental; Triazenes | 2006 |
Rabies virus infection of primary neuronal cultures and adult mice: failure to demonstrate evidence of excitotoxicity.
Topics: Animals; Apoptosis; Caspase 3; Caspase Inhibitors; Cells, Cultured; Cysteine Proteinase Inhibitors; Disease Models, Animal; Excitatory Amino Acid Antagonists; Ketamine; Mice; N-Methylaspartate; Neurons; Oligopeptides; Rabies; Rabies virus | 2006 |
Effect of gabaergic, glutamatergic, antipsychotic and antidepressant drugs on pilocarpine-induced seizures and status epilepticus.
Topics: Amines; Amitriptyline; Animals; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagonists; Fluoxetine; Gabapentin; gamma-Aminobutyric Acid; Humans; Ketamine; Male; Muscarinic Agonists; N-Methylaspartate; Pilocarpine; Pimozide; Rats; Seizures; Status Epilepticus | 2006 |
Cysteinyl leukotriene receptor 1 is involved in N-methyl-D-aspartate-mediated neuronal injury in mice.
Topics: Animals; Antioxidants; Antipyrine; Brain; Brain Injuries; Chromones; Edaravone; Ketamine; Male; Membrane Proteins; Mice; N-Methylaspartate; Neurons; Receptors, Leukotriene; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Up-Regulation | 2006 |
Study pharmacologic of the GABAergic and glutamatergic drugs on seizures and status epilepticus induced by pilocarpine in adult Wistar rats.
Topics: Amines; Animals; Anticonvulsants; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Ketamine; Male; Muscarinic Agonists; N-Methylaspartate; Phenobarbital; Pilocarpine; Rats; Rats, Wistar; Receptors, GABA; Receptors, Neurotransmitter; Seizures; Status Epilepticus; Vigabatrin | 2007 |
Behavioral sensitization to ethanol does not result in cross-sensitization to NMDA receptor antagonists.
Topics: Animals; Behavior, Animal; Central Nervous System Depressants; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Tolerance; Ethanol; Excitatory Amino Acid Agonists; Female; Hypersensitivity; Infusions, Intravenous; Injections, Intraperitoneal; Ketamine; Male; Mice; Mice, Inbred DBA; Motor Activity; N-Methylaspartate; Receptors, N-Methyl-D-Aspartate; Sensory Thresholds; Stereotyped Behavior; Time Factors | 2007 |
Central nervous tissue: an excitable medium. a study using the retinal spreading depression as a tool.
Topics: Animals; Chickens; Cortical Spreading Depression; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Ketamine; N-Methylaspartate; Retina; Video Recording | 2008 |
Neonatal exposure to a combination of N-methyl-D-aspartate and gamma-aminobutyric acid type A receptor anesthetic agents potentiates apoptotic neurodegeneration and persistent behavioral deficits.
Topics: Analgesics; Anesthetics, Combined; Anesthetics, Intravenous; Animals; Animals, Newborn; Anti-Anxiety Agents; Apoptosis; Behavior, Animal; Brain; Diazepam; Disease Models, Animal; Drug Combinations; Drug Synergism; Excitatory Amino Acid Agonists; GABA Antagonists; Ketamine; Male; Maze Learning; Mice; N-Methylaspartate; Neurodegenerative Diseases; Propofol; Receptors, GABA-A; Sodium Chloride; Thiopental; Time Factors | 2007 |
Searching for rational anti N-methyl-D-aspartate treatment for depression.
Topics: Cognition Disorders; Depressive Disorder; Excitatory Amino Acid Antagonists; Humans; Ketamine; N-Methylaspartate; Neurodegenerative Diseases; Psychoses, Substance-Induced; Receptors, N-Methyl-D-Aspartate | 2007 |
Toxicology profile of N-methyl-D-aspartate antagonists delivered by intrathecal infusion in the canine model.
Topics: Amitriptyline; Animals; Dizocilpine Maleate; Dogs; Female; Infusion Pumps, Implantable; Infusions, Parenteral; Ketamine; Male; Memantine; Models, Animal; N-Methylaspartate; Sulfamethizole | 2008 |
Erythropoietin improves oxidative stress following spinal cord trauma in rats.
Topics: Analgesics; Animals; Antioxidants; Erythropoietin; Glutathione; Ketamine; Lipid Peroxidation; Malondialdehyde; N-Methylaspartate; Neuroprotective Agents; Oxidative Stress; Rats; Rats, Wistar; Spinal Cord Injuries; Spinal Cord Ischemia | 2008 |
N-methyl-D-aspartate (NMDA) antagonists--S(+)-ketamine, dextrorphan, and dextromethorphan--act as calcium antagonists on bovine cerebral arteries.
Topics: Animals; Calcium; Calcium Channel Blockers; Calcium Radioisotopes; Cattle; Dextromethorphan; Dextrorphan; Dose-Response Relationship, Drug; Electric Stimulation; Excitatory Amino Acid Agonists; In Vitro Techniques; Isometric Contraction; Ketamine; Middle Cerebral Artery; Muscle Tonus; Muscle, Smooth, Vascular; N-Methylaspartate; Nimodipine; Vascular Resistance; Vasoconstrictor Agents | 2008 |
Prevention of N-methyl-D-aspartate-induced mechanical nociception by intrathecal administration of ketoprofen and ketamine in sheep.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Female; Injections, Spinal; Ketamine; Ketoprofen; N-Methylaspartate; Pain; Sheep; Xylans | 2008 |
NMDA receptor antagonists augment antidepressant-like effects of lithium in the mouse forced swimming test.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Injections, Intraperitoneal; Ketamine; Lithium Chloride; Male; Mice; Models, Animal; Motor Activity; N-Methylaspartate; Piperidines; Receptors, N-Methyl-D-Aspartate; Swimming; Time Factors | 2010 |
The role of the mGluR allosteric modulation in the NMDA-hypofunction model of schizophrenia.
Topics: Allosteric Regulation; Animals; Disease Models, Animal; Humans; Ketamine; N-Methylaspartate; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Schizophrenia | 2009 |
Hyperphosphorylated tau in the brains of mice and monkeys with long-term administration of ketamine.
Topics: Animals; Entorhinal Cortex; In Situ Nick-End Labeling; Ketamine; Macaca fascicularis; Mice; N-Methylaspartate; Phosphorylation; Prefrontal Cortex; tau Proteins | 2010 |
Ketamine inhibits tumor necrosis factor secretion by RAW264.7 murine macrophages stimulated with antibiotic-exposed strains of community-associated, methicillin-resistant Staphylococcus aureus.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anti-Bacterial Agents; Cell Line; Daptomycin; Dizocilpine Maleate; Drug Synergism; Ketamine; Macrophage Activation; Macrophages; Methicillin-Resistant Staphylococcus aureus; Mice; N-Methylaspartate; Receptors, N-Methyl-D-Aspartate; Time Factors; Tumor Necrosis Factor-alpha; Vancomycin | 2011 |
Assessment of general anaesthetic cytotoxicity in murine cortical neurones in dissociated culture.
Topics: Anesthetics, General; Animals; Animals, Newborn; Cell Survival; Cerebral Cortex; gamma-Aminobutyric Acid; Isoflurane; Ketamine; L-Lactate Dehydrogenase; Mice; Mice, Inbred C57BL; Microscopy, Fluorescence; Microtubule-Associated Proteins; N-Methylaspartate; Neurons; Nitrous Oxide | 2011 |
Rapid decrease in depressive symptoms with an N-methyl-d-aspartate antagonist in ECT-resistant major depression.
Topics: Adolescent; Adult; Aged; Depressive Disorder, Major; Electroconvulsive Therapy; Excitatory Amino Acid Antagonists; Female; Humans; Injections, Intravenous; Ketamine; Linear Models; Male; Middle Aged; N-Methylaspartate; Psychiatric Status Rating Scales; Sample Size; Socioeconomic Factors; Treatment Failure; Young Adult | 2011 |
Antagonism of stimulation-produced analgesia by naloxone and N-methyl-D-aspartate: role of opioid and N-methyl-D-aspartate receptors.
Topics: Analgesia; Analgesics, Opioid; Animals; Disease Models, Animal; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Hot Temperature; Ketamine; Male; Morphine; N-Methylaspartate; Naloxone; Narcotic Antagonists; Neuralgia; Periaqueductal Gray; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid; Sciatic Nerve | 2012 |
Antitussive effects of memantine in guinea pigs.
Topics: Animals; Antitussive Agents; Baclofen; Bradykinin; Citric Acid; Cough; Dextromethorphan; Guinea Pigs; Ketamine; Male; Mecamylamine; Memantine; N-Methylaspartate; Serotonin | 2012 |
Effects of general anaesthetics on 5-HT neuronal activity in the dorsal raphe nucleus.
Topics: Action Potentials; Anesthetics, General; Animals; Chloral Hydrate; Hypnotics and Sedatives; Isoxazoles; Ketamine; Male; N-Methylaspartate; Pentobarbital; Raphe Nuclei; Rats; Serotonergic Neurons; Serotonin; Urethane | 2012 |
Dual regulation by ethanol of the inhibitory effects of ketamine on spinal NMDA-induced pressor responses in rats.
Topics: Animals; Blotting, Western; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Ethanol; Injections, Spinal; Ketamine; Male; N-Methylaspartate; Phosphorylation; Phosphoserine; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Thionucleotides; Time Factors | 2012 |
Impact of early-life stress, on group III mGlu receptor levels in the rat hippocampus: effects of ketamine, electroconvulsive shock therapy and fluoxetine treatment.
Topics: Animals; Antidepressive Agents; Electroshock; Excitatory Amino Acid Antagonists; Fluoxetine; Hippocampus; Ketamine; Male; Maternal Deprivation; N-Methylaspartate; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Stress, Psychological | 2013 |
Involvement of NMDA receptors in the antidepressant-like action of adenosine.
Topics: Adenosine; Animals; Antidepressive Agents; Antidepressive Agents, Tricyclic; Chlorides; Depression; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Synergism; Imipramine; Immobilization; Ketamine; Male; Mice; N-Methylaspartate; Receptor, Adenosine A1; Receptors, N-Methyl-D-Aspartate; Serine; Swimming; Time Factors; Zinc Compounds | 2012 |
The promise of rapidly acting antidepressants: challenges and opportunities.
Topics: Antidepressive Agents; Depression; Drug Discovery; Humans; Ketamine; N-Methylaspartate | 2012 |
Role of NMDA and opioid receptors in neuropathic pain induced by chronic constriction injury of sciatic nerve in rats.
Topics: Analgesics, Opioid; Animals; Disease Models, Animal; Excitatory Amino Acid Agonists; Ketamine; Male; Morphine; N-Methylaspartate; Naloxone; Narcotic Antagonists; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid; Sciatic Neuropathy | 2012 |
Effects of ketamine and its metabolites on ion currents in differentiated hippocampal H19-7 neuronal cells and in HEK293T cells transfected with α-hslo subunit.
Topics: Adjuvants, Immunologic; Animals; Biophysics; Calcium; Cell Differentiation; Cell Line; Diterpenes; Electric Stimulation; Electroporation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Humans; Ketamine; Large-Conductance Calcium-Activated Potassium Channels; Lithium Chloride; Membrane Potentials; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Rats; Time Factors; Transfection | 2012 |
Hierarchical and binary associations compete for behavioral control during instrumental biconditional discrimination.
Topics: Animals; Association Learning; Conditioning, Operant; Corpus Striatum; Discrimination, Psychological; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Extinction, Psychological; Ketamine; Male; Maze Learning; N-Methylaspartate; Rats; Rats, Long-Evans | 2013 |
In vitro dose-dependent inhibition of the intracellular spontaneous calcium oscillations in developing hippocampal neurons by ketamine.
Topics: Analgesics; Animals; Apoptosis; Calcium Signaling; Collagen; Dose-Response Relationship, Drug; Drug Combinations; Gene Expression Regulation, Developmental; Hippocampus; Ketamine; Laminin; Microscopy, Confocal; N-Methylaspartate; Neurons; Oscillometry; Proteoglycans; Rats; Rats, Sprague-Dawley; Time Factors | 2013 |
Ketamine, but not MK-801, produces antidepressant-like effects in rats responding on a differential-reinforcement-of-low-rate operant schedule.
Topics: Animals; Antidepressive Agents; Conditioning, Operant; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Combinations; Excitatory Amino Acid Antagonists; Imipramine; Ketamine; Male; N-Methylaspartate; Rats; Rats, Sprague-Dawley; Reinforcement Schedule; Reinforcement, Psychology | 2014 |
Relationship between glycine transporter 1 inhibition as measured with positron emission tomography and changes in cognitive performances in nonhuman primates.
Topics: Animals; Benzamides; Brain; Carbon Radioisotopes; Central Nervous System Agents; Excitatory Amino Acid Antagonists; Female; Glycine Plasma Membrane Transport Proteins; Ketamine; Macaca mulatta; Male; Memory, Short-Term; N-Methylaspartate; Neuropsychological Tests; Positron-Emission Tomography; Radiopharmaceuticals; Spatial Memory; Tetrahydronaphthalenes | 2014 |
Effects of ketamine and N-methyl-D-aspartate on fluoxetine-induced antidepressant-related behavior using the forced swimming test.
Topics: Animals; Antidepressive Agents, Second-Generation; Behavior, Animal; Depression; Fluoxetine; Ketamine; Mice; N-Methylaspartate; Receptors, N-Methyl-D-Aspartate; Swimming; Synaptic Transmission | 2014 |
Ketamine affects the neurogenesis of rat fetal neural stem progenitor cells via the PI3K/Akt-p27 signaling pathway.
Topics: Analgesics; Animals; Brain; Cell Proliferation; Cells, Cultured; Cyclin-Dependent Kinase Inhibitor p27; Ketamine; MAP Kinase Signaling System; N-Methylaspartate; Neural Stem Cells; Neurogenesis; Phosphatidylinositol 3-Kinases; Phosphorylation; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 2014 |
Ketamine modulates TRH and TRH-like peptide turnover in brain and peripheral tissues of male rats.
Topics: Animals; Brain; Depressive Disorder, Major; Humans; Ketamine; Male; N-Methylaspartate; Peptides; Rats; Rats, Sprague-Dawley; Suicide; Thyrotropin-Releasing Hormone | 2015 |
Ketamine-Induced Toxicity in Neurons Differentiated from Neural Stem Cells.
Topics: Animals; Apoptosis; Astrocytes; Calcium; Cell Division; Cells, Cultured; Cerebral Cortex; Culture Media; DNA Damage; Dose-Response Relationship, Drug; Extracellular Fluid; Glycine; Intercellular Signaling Peptides and Proteins; Ketamine; Mitochondria; N-Methylaspartate; Necrosis; Nerve Degeneration; Neural Stem Cells; Neurogenesis; Neurons; Oligodendroglia; Rats; Rats, Sprague-Dawley | 2015 |
Ketamine promotes inflammation through increasing TLR4 expression in RAW264.7 cells.
Topics: Anesthetics, Dissociative; Animals; Cell Survival; Gene Expression Regulation; Inflammation Mediators; Interleukin-6; Ketamine; Lipopolysaccharides; Macrophages; Male; Mice; N-Methylaspartate; RAW 264.7 Cells; Signal Transduction; Toll-Like Receptor 4; Tumor Necrosis Factor-alpha | 2015 |
The nitric oxide donor sodium nitroprusside attenuates recognition memory deficits and social withdrawal produced by the NMDA receptor antagonist ketamine and induces anxiolytic-like behaviour in rats.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Excitatory Amino Acid Antagonists; Ketamine; Male; Memory Disorders; Motor Activity; N-Methylaspartate; Nitric Oxide Donors; Nitroprusside; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Recognition, Psychology; Social Behavior | 2016 |
Antidepressant action of ketamine via mTOR is mediated by inhibition of nitrergic Rheb degradation.
Topics: Animals; Antidepressive Agents; Cells, Cultured; Cerebral Cortex; Cysteine; Depression; Disease Models, Animal; Embryo, Mammalian; Exploratory Behavior; Female; Gene Expression Regulation; HEK293 Cells; Humans; Ketamine; Male; Mice, Inbred C57BL; Mice, Knockout; Monomeric GTP-Binding Proteins; N-Methylaspartate; Neurons; Neuropeptides; Nitric Oxide; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Pregnancy; Proteolysis; Ras Homolog Enriched in Brain Protein; S-Nitrosothiols; Signal Transduction; Swimming; Time Factors; TOR Serine-Threonine Kinases | 2016 |
N-Methyl-D-Aspartate Receptors, Ketamine, and Rett Syndrome: Something Special on the Road to Treatments?
Topics: Excitatory Amino Acid Antagonists; Humans; Ketamine; N-Methylaspartate; Receptors, N-Methyl-D-Aspartate; Rett Syndrome; Spinal Cord | 2016 |
GSK-3: A key regulatory target for ketamine's rapid antidepressant effects mediated by enhanced AMPA to NMDA throughput.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Antidepressive Agents; Bipolar Disorder; Glycogen Synthase Kinase 3; Humans; Ketamine; N-Methylaspartate; Receptors, N-Methyl-D-Aspartate | 2016 |
Ketamine upregulates eNOS expression in human astroglial A172 cells: Possible role in its antidepressive properties.
Topics: Astrocytes; Cell Line, Transformed; Dose-Response Relationship, Drug; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glioblastoma; Humans; Immunosuppressive Agents; Ketamine; MAP Kinase Signaling System; N-Methylaspartate; Nitric Oxide Synthase Type III; RNA, Messenger; Sirolimus; Time Factors; Up-Regulation; Valine | 2017 |
Involvement of NMDA receptors in the antidepressant-like effect of tramadol in the mouse forced swimming test.
Topics: Animals; Antidepressive Agents; Depressive Disorder; Disease Models, Animal; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Agents; Ketamine; Magnesium Sulfate; Male; Mice; N-Methylaspartate; Receptors, N-Methyl-D-Aspartate; Swimming; Tramadol | 2017 |
Synthesis and N-Methyl-d-aspartate (NMDA) Receptor Activity of Ketamine Metabolites.
Topics: Antidepressive Agents; Ketamine; Molecular Structure; N-Methylaspartate; Receptors, N-Methyl-D-Aspartate | 2017 |
BDNF release and signaling are required for the antidepressant actions of GLYX-13.
Topics: Animals; Antidepressive Agents; Brain-Derived Neurotrophic Factor; Depression; Ketamine; Male; Membrane Glycoproteins; Mice; Mice, Inbred C57BL; N-Methylaspartate; Oligopeptides; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Receptor, trkB; Receptors, N-Methyl-D-Aspartate; Signal Transduction | 2018 |
Ketamine-induced neurotoxicity blocked by N-Methyl-d-aspartate is mediated through activation of PKC/ERK pathway in developing hippocampal neurons.
Topics: Anesthetics, Dissociative; Animals; Apoptosis; Cell Cycle; Cells, Cultured; Dose-Response Relationship, Drug; Hippocampus; Ketamine; MAP Kinase Signaling System; N-Methylaspartate; Neurons; Protein Kinase C; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 2018 |
Modeling Schizophrenia's Abnormal Cortical Neural Synchrony in Monkeys.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Haplorhini; Humans; Ketamine; N-Methylaspartate; Schizophrenia | 2018 |
NMDA Antagonists for Treatment-Resistant Depression.
Topics: Depression; Depressive Disorder, Major; Humans; Ketamine; N-Methylaspartate; Pilot Projects | 2019 |
NMDA 2A receptors in parvalbumin cells mediate sex-specific rapid ketamine response on cortical activity.
Topics: Animals; Estrous Cycle; Female; Interneurons; Ketamine; Male; Mice; Mice, Inbred C57BL; N-Methylaspartate; Parvalbumins; Prefrontal Cortex; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Sex Factors | 2019 |
Ketamine disrupts neuromodulatory control of glutamatergic synaptic transmission.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Brain; Depression; Female; Glutamine; Ketamine; Male; Mice; Mice, Inbred C57BL; N-Methylaspartate; Neurons; Neurotransmitter Agents; Prefrontal Cortex; Receptors, AMPA; Receptors, GABA; Signal Transduction; Swimming; Synapses; Synaptic Potentials; Synaptic Transmission; Video Recording | 2019 |
Lasting s-ketamine block of spreading depolarizations in subarachnoid hemorrhage: a retrospective cohort study.
Topics: Adult; Aged; Cohort Studies; Female; Humans; Hypnotics and Sedatives; Ketamine; Length of Stay; Male; Midazolam; Middle Aged; N-Methylaspartate; Neuromuscular Depolarizing Agents; Odds Ratio; Retrospective Studies; Subarachnoid Hemorrhage | 2019 |
Are NMDA and opioid receptors involved in the antidepressant actions of ketamine?
Topics: Animals; Antidepressive Agents; Depression; Ketamine; N-Methylaspartate; Receptors, Opioid; Rodentia | 2020 |
Ketamine, NMDA hypofunction, and sleep oscillatory abnormalities in schizophrenia.
Topics: Humans; Ketamine; N-Methylaspartate; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Sleep | 2020 |
Topics: Adult; Anesthetics, Dissociative; Calcium; Cells, Cultured; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Gene Expression; Humans; Ion Transport; Ketamine; Male; N-Methylaspartate; Receptors, N-Methyl-D-Aspartate; Spermatozoa | 2021 |
Role of Different Doses of Ketamine in Postoperative Neurocognitive Function in Aged Mice Undergoing Partial Hepatectomy by Regulating the Bmal1/NMDA/NF-Κb Axis.
Topics: Animals; Hepatectomy; Ketamine; Mice; N-Methylaspartate; NF-kappa B; Receptors, N-Methyl-D-Aspartate; Synapsins | 2022 |
Negative Allosteric Modulation of Gamma-Aminobutyric Acid A Receptors at α5 Subunit-Containing Benzodiazepine Sites Reverses Stress-Induced Anhedonia and Weakened Synaptic Function in Mice.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Anhedonia; Animals; Benzodiazepines; Female; gamma-Aminobutyric Acid; Humans; Ketamine; Male; Mice; N-Methylaspartate; Receptors, GABA; Receptors, GABA-A; Sucrose | 2022 |
The Role of the NMDA Receptor in the Anticonvulsant Effect of Ellagic Acid in Pentylenetetrazole-Induced Seizures in Male Mice.
Topics: Animals; Anticonvulsants; Dose-Response Relationship, Drug; Ellagic Acid; Ketamine; Male; Mice; N-Methylaspartate; Pentylenetetrazole; Receptors, N-Methyl-D-Aspartate; Seizures | 2022 |
The effect of ketamine on delta-range coupling between prefrontal cortex and hippocampus supported by respiratory rhythmic input from the olfactory bulb.
Topics: Animals; Hippocampus; Humans; Ketamine; N-Methylaspartate; Olfactory Bulb; Prefrontal Cortex; Rats | 2022 |
Adjunctive dopaminergic enhancement of esketamine in treatment-resistant depression.
Topics: Bupropion; Depression; Depressive Disorder, Treatment-Resistant; Dopamine; Humans; Ketamine; N-Methylaspartate | 2022 |
The effect of ketamine and D-cycloserine on the high frequency resting EEG spectrum in humans.
Topics: Cross-Over Studies; Cycloserine; Double-Blind Method; Electroencephalography; Humans; Ketamine; Male; N-Methylaspartate; Receptors, N-Methyl-D-Aspartate | 2023 |
NMDA Receptor Activation-Dependent Antidepressant-Relevant Behavioral and Synaptic Actions of Ketamine.
Topics: Animals; Antidepressive Agents; Depression; Ketamine; Male; Mice; N-Methylaspartate; Receptors, N-Methyl-D-Aspartate | 2023 |
"Anti-cancer" effect of ketamine in comparison with MK801 on neuroglioma and lung cancer cells.
Topics: Apoptosis; Caspase 3; Cyclin D1; Dizocilpine Maleate; Humans; Ketamine; Lung Neoplasms; Matrix Metalloproteinase 9; N-Methylaspartate; Reactive Oxygen Species; Receptors, N-Methyl-D-Aspartate | 2023 |
Opposite Modulation of the NMDA Receptor by Glycine and S-Ketamine and the Effects on Resting State EEG Gamma Activity: New Insights into the Glutamate Hypothesis of Schizophrenia.
Topics: Biomarkers; Electroencephalography; Glutamic Acid; Humans; Ketamine; Male; N-Methylaspartate; Receptors, N-Methyl-D-Aspartate; Schizophrenia | 2023 |
Characterizing brain dynamics during ketamine-induced dissociation and subsequent interactions with propofol using human intracranial neurophysiology.
Topics: Antidepressive Agents; Cerebral Cortex; Humans; Ketamine; N-Methylaspartate; Neurophysiology; Propofol; Receptors, N-Methyl-D-Aspartate | 2023 |
Low-Dose Ketamine-Induced Deficits in Arbitrary Visuomotor Mapping in Monkeys.
Topics: Animals; Brain; Haplorhini; Ketamine; Memory, Short-Term; N-Methylaspartate | 2023 |
A Network Model of the Modulation of γ Oscillations by NMDA Receptors in Cerebral Cortex.
Topics: Cerebral Cortex; Excitatory Amino Acid Antagonists; Humans; Ketamine; N-Methylaspartate; Receptors, N-Methyl-D-Aspartate | 2023 |