n-methylaspartate has been researched along with gyki 52466 in 27 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 20 (74.07) | 18.2507 |
| 2000's | 7 (25.93) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Arvin, B; Le Peillet, E; Meldrum, BS; Moncada, C | 1 |
| Durand, J; Ouardouz, M | 1 |
| Meldrum, BS; Smith, SE | 1 |
| Barnes, KA; Buchan, AM; Huang, ZG; Lesiuk, H; Li, H; Smith, KE; Xue, D | 1 |
| Barnes, K; Buchan, AM; Huang, ZG; Lesiuk, HJ; Smith, KE; Xue, D | 1 |
| Gyevai, A; Mike, A; Osipenko, O; Vizi, ES | 1 |
| Gruner, R; Parsons, CG; Rozental, J | 1 |
| Balázs, R; Hack, N | 1 |
| Durand, J; Engberg, I; Ouardouz, M; Tarnawa, I | 1 |
| Champagnat, J; Denavit-Saubié, M; Foutz, AS; Pierrefiche, O | 1 |
| De Bernardi, R; Ferro, F; Fontana, G; Gemignani, A; Raiteri, M | 1 |
| Czuczwar, SJ; Kleinrok, Z; Turski, WA; Tutka, P | 1 |
| McCaslin, PP; Oh, S | 1 |
| Regan, RF | 1 |
| Cole, BJ; Stephens, DN | 1 |
| Bleuel, Z; Clifford, MM; Ellis, GJ; Humbel, U; Klingelschmidt, A; Messer, J; Mutel, V; Richards, JG; Trube, G | 1 |
| Kratzer, U; Kretschmer, BD; Schmidt, WJ | 1 |
| Donevan, SD; Rogawski, MA | 1 |
| Blanco, R; de la Villa, P | 1 |
| Chen, Q; Reiner, A; Surmeier, DJ | 1 |
| Caicedo, A; Jafri, MS; Roper, SD | 1 |
| Kristensen, BW; Noraberg, J; Zimmer, J | 1 |
| Choi, JH; Chun, SW; Kim, MS; Park, BR | 1 |
| Caicedo, A; Eybalin, M; Puel, JL; Renard, N; Ruel, J | 1 |
| Bennett, SA; Cheung, EC; Cregan, SP; Ferguson, KL; McIntosh, WC; Melanson-Drapeau, L; Park, DS; Slack, RS; Vanderluit, JL | 1 |
| Tian, M; Yang, XL | 1 |
| June Liu, S; Sun, L | 1 |
27 other study(ies) available for n-methylaspartate and gyki 52466
| Article | Year |
|---|---|
Non-NMDA antagonists protect against kainate more than AMPA toxicity in the rat hippocampus.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Benzodiazepines; Hippocampus; Ibotenic Acid; Kainic Acid; Male; N-Methylaspartate; Nerve Degeneration; Neurons; Neurotoxins; Pyramidal Tracts; Quinoxalines; Rats; Rats, Inbred Strains | 1991 |
GYKI 52466 antagonizes glutamate responses but not NMDA and kainate responses in rat abducens motoneurones.
Topics: Abducens Nerve; Animals; Anti-Anxiety Agents; Benzodiazepines; Electric Stimulation; Evoked Potentials; Excitatory Amino Acid Antagonists; Glutamates; Kainic Acid; Male; Motor Neurons; N-Methylaspartate; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate | 1991 |
Receptor site specificity for the acute effects of beta-N-methylamino-alanine in mice.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids, Diamino; Animals; Anti-Anxiety Agents; Anticonvulsants; Behavior, Animal; Benzodiazepines; Cyanobacteria Toxins; Glutamine; Ibotenic Acid; Injections, Intraventricular; Kainic Acid; Kinetics; Male; Mice; N-Methylaspartate; Organophosphorus Compounds; Piperazines; Receptors, Drug; Receptors, N-Methyl-D-Aspartate | 1990 |
AMPA antagonists: do they hold more promise for clinical stroke trials than NMDA antagonists?
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Benzodiazepines; Cerebral Infarction; Cerebrovascular Disorders; Dizocilpine Maleate; Drug Administration Schedule; Injections, Intraperitoneal; Male; N-Methylaspartate; Quinoxalines; Rats; Rats, Wistar; Reperfusion | 1993 |
Delayed treatment with AMPA, but not NMDA, antagonists reduces neocortical infarction.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Benzodiazepines; Cerebral Cortex; Cerebral Infarction; Cerebrovascular Circulation; Injections, Intraperitoneal; Injections, Intravenous; Kidney; Male; N-Methylaspartate; Pilot Projects; Quinoxalines; Rats; Rats, Inbred SHR; Sodium Chloride | 1994 |
Evidence that GYKI 52466, a novel non-NMDA antagonist enhances the decay of kainate-induced current in cultured chicken cortical neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Benzodiazepines; Cerebral Cortex; Chick Embryo; Electrophysiology; Excitatory Amino Acid Antagonists; Ion Channels; Kainic Acid; Membrane Potentials; N-Methylaspartate; Neurons; Neurotoxins; Quinoxalines | 1994 |
Comparative patch clamp studies on the kinetics and selectivity of glutamate receptor antagonism by 2,3-dihydroxy-6-nitro-7-sulfamoyl-benzo(F)quinoxaline (NBQX) and 1-(4-amino-phenyl)-4-methyl-7,8-methyl-endioxyl-5H-2,3-benzodiaze pine (GYKI 52466).
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Benzodiazepines; Cells, Cultured; Excitatory Amino Acid Antagonists; Hippocampus; Kainic Acid; Kinetics; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Quinoxalines; Rats; Receptors, AMPA; Superior Colliculi | 1994 |
Properties of AMPA receptors expressed in rat cerebellar granule cell cultures: Ca2+ influx studies.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Benzodiazepines; Benzothiadiazines; Calcium; Calcium Radioisotopes; Cell Survival; Cells, Cultured; Cerebellum; Cobalt; Concanavalin A; Excitatory Amino Acids; Kainic Acid; N-Methylaspartate; Quinoxalines; Rats; Receptors, AMPA; Wheat Germ Agglutinins | 1995 |
An analysis of synaptic transmission to motoneurones in the cat spinal cord using a new selective receptor blocker.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Cats; Electrophysiology; Female; Ibotenic Acid; Male; Motor Neurons; N-Methylaspartate; Spinal Cord; Synapses; Synaptic Transmission | 1993 |
NMDA and non-NMDA receptors may play distinct roles in timing mechanisms and transmission in the feline respiratory network.
Topics: Action Potentials; Anesthesia; Animals; Anti-Anxiety Agents; Benzodiazepines; Blood Pressure; Carbon Dioxide; Cats; Dizocilpine Maleate; N-Methylaspartate; Neurons; Phrenic Nerve; Pulmonary Alveoli; Quinoxalines; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Reflex; Respiration; Synaptic Transmission; Time Factors | 1994 |
Characterization of the glutamate receptors mediating release of somatostatin from cultured hippocampal neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Benzodiazepines; Calcium; Cells, Cultured; Cycloleucine; Dizocilpine Maleate; Drug Synergism; Glutamic Acid; Hippocampus; Kainic Acid; N-Methylaspartate; Pyramidal Cells; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Somatostatin; Tetrodotoxin | 1996 |
Influence of aminophylline and strychnine on the protective activity of excitatory amino acid antagonists against maximal electroshock-induced convulsions in mice.
Topics: Aminophylline; Animals; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Convulsants; Electroshock; Excitatory Amino Acid Antagonists; Male; Mice; N-Methylaspartate; Phosphodiesterase Inhibitors; Piperazines; Seizures; Strychnine; Valproic Acid | 1996 |
Kainate produces concentration-dependent elevation of glutamate release but not cGMP levels in cultured neuron.
Topics: Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Cerebellum; Cyclic GMP; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Kainic Acid; N-Methylaspartate; Neurons; Neurotoxins; Piperazines; Quinoxalines | 1996 |
The vulnerability of spinal cord neurons to excitotoxic injury: comparison with cortical neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Benzodiazepines; Cerebral Cortex; Cobalt; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Kainic Acid; Mice; N-Methylaspartate; Neurons; Neurotoxins; Spinal Cord; Staining and Labeling; Time Factors | 1996 |
AMPA antagonists differ from NMDA antagonists in their effects on operant DRL and delayed matching to position tasks.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Benzodiazepines; Conditioning, Operant; Discrimination, Psychological; Dizocilpine Maleate; Dose-Response Relationship, Drug; Male; N-Methylaspartate; Quinoxalines; Rats; Rats, Wistar; Reinforcement, Psychology | 1996 |
Binding characteristics of a potent AMPA receptor antagonist [3H]Ro 48-8587 in rat brain.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Benzodiazepines; Brain Chemistry; Dizocilpine Maleate; Electrophysiology; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Imidazoles; In Situ Hybridization; Kainic Acid; Kinetics; Male; N-Methylaspartate; Quinazolines; Quinoxalines; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, AMPA; RNA, Messenger; Tritium | 1998 |
Riluzole, a glutamate release inhibitor, and motor behavior.
Topics: Animals; Anti-Anxiety Agents; Antipsychotic Agents; Behavior, Animal; Benzazepines; Benzodiazepines; Catalepsy; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Haloperidol; Locomotion; Male; Motor Activity; N-Methylaspartate; Neuropsychological Tests; Postural Balance; Psychomotor Performance; Rats; Rats, Sprague-Dawley; Riluzole; Smell | 1998 |
Allosteric regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole-propionate receptors by thiocyanate and cyclothiazide at a common modulatory site distinct from that of 2,3-benzodiazepines.
Topics: Allosteric Regulation; Animals; Anti-Anxiety Agents; Antihypertensive Agents; Benzodiazepines; Benzothiadiazines; Binding Sites; Cells, Cultured; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Hippocampus; Ion Channel Gating; Kainic Acid; Membrane Potentials; N-Methylaspartate; Neurons; Oocytes; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Thiocyanates; Xenopus | 1998 |
Ionotropic glutamate receptors in isolated horizontal cells of the rabbit retina.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Benzodiazepines; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Ion Channel Gating; Kainic Acid; Membrane Potentials; N-Methylaspartate; Patch-Clamp Techniques; Quinoxalines; Rabbits; Receptors, AMPA; Receptors, Kainic Acid; Retina | 1999 |
NMDA and non-NMDA receptor-mediated excitotoxicity are potentiated in cultured striatal neurons by prior chronic depolarization.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Benzodiazepines; Calcium; Cells, Cultured; Corpus Striatum; Cycloleucine; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Female; Fetus; GluK2 Kainate Receptor; GluK3 Kainate Receptor; Kainic Acid; Membrane Potentials; N-Methylaspartate; Nerve Degeneration; Neurons; Neuroprotective Agents; Neurotoxins; Potassium Chloride; Pregnancy; Quinolinic Acid; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Kainic Acid; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate | 1999 |
In situ Ca2+ imaging reveals neurotransmitter receptors for glutamate in taste receptor cells.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Benzodiazepines; Calcium; Cells, Cultured; Dextrans; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Female; Fluorescent Dyes; Glutamic Acid; In Vitro Techniques; Kainic Acid; Male; Microscopy, Confocal; N-Methylaspartate; Neurotransmitter Agents; Organic Chemicals; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Glutamate; Taste Buds | 2000 |
Comparison of excitotoxic profiles of ATPA, AMPA, KA and NMDA in organotypic hippocampal slice cultures.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Benzodiazepines; Dizocilpine Maleate; Dose-Response Relationship, Drug; Hippocampus; In Vitro Techniques; Isoxazoles; Kainic Acid; Microtubule-Associated Proteins; N-Methylaspartate; Neuroprotective Agents; Neurotoxins; Nissl Bodies; Nuclear Proteins; Propidium; Propionates; Quinoxalines; Rats; Rats, Wistar | 2001 |
Characterization of spontaneous synaptic transmission in rat medial vestibular nucleus.
Topics: 2-Amino-5-phosphonovalerate; Animals; Benzodiazepines; Bicuculline; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; GABA-A Receptor Antagonists; Glycine Agents; In Vitro Techniques; Kinetics; N-Methylaspartate; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Strychnine; Synaptic Transmission; Vestibular Nuclei | 2003 |
Transient Ca2+-permeable AMPA receptors in postnatal rat primary auditory neurons.
Topics: Age Factors; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Benzodiazepines; Blotting, Western; Calcium; Cobalt; Cochlea; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Fluorescent Antibody Technique; Gene Expression Regulation, Developmental; Glycine; In Vitro Techniques; Microscopy, Confocal; N-Methylaspartate; Neurons; Parvalbumins; Peptides, Cyclic; Permeability; Rats; Rats, Wistar; Receptors, AMPA; Spider Venoms | 2004 |
Apoptosis-inducing factor is a key factor in neuronal cell death propagated by BAX-dependent and BAX-independent mechanisms.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Apoptosis; Apoptosis Inducing Factor; Apoptotic Protease-Activating Factor 1; bcl-2-Associated X Protein; Benzodiazepines; Benzothiadiazines; Camptothecin; Caspase Inhibitors; Cells, Cultured; Cerebellum; Cerebral Cortex; Convulsants; Dizocilpine Maleate; Drug Resistance; Flavoproteins; Glutamic Acid; Glycine; Hippocampus; Kainic Acid; Male; Membrane Proteins; Mice; Mice, Knockout; Mice, Mutant Strains; N-Methylaspartate; Neurons; Neurotoxins; Proteins; Proto-Oncogene Proteins c-bcl-2; Recombinant Fusion Proteins; Seizures | 2005 |
C-type natriuretic peptide modulates glutamate receptors on cultured rat retinal amacrine cells.
Topics: Amacrine Cells; Animals; Animals, Newborn; Benzodiazepines; Blotting, Western; Cells, Cultured; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Glutamic Acid; Immunohistochemistry; Isoenzymes; Membrane Potentials; N-Methylaspartate; Natriuretic Agents; Natriuretic Peptide, C-Type; Patch-Clamp Techniques; Polysaccharides; Rats; Receptors, Glutamate; Retina; Syntaxin 1 | 2006 |
Activation of extrasynaptic NMDA receptors induces a PKC-dependent switch in AMPA receptor subtypes in mouse cerebellar stellate cells.
Topics: Animals; Benzodiazepines; Calcium; Carrier Proteins; Cell Cycle Proteins; Cerebellum; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Mice; Mice, Inbred C57BL; N-Methylaspartate; Neuronal Plasticity; Nuclear Proteins; Organophosphonates; Peptide Fragments; Piperazines; Protein Kinase C; Protein Kinase Inhibitors; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Synapses; Synaptic Transmission; Time Factors | 2007 |