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n-methylaspartate and enkephalin, ala(2)-mephe(4)-gly(5)-

n-methylaspartate has been researched along with enkephalin, ala(2)-mephe(4)-gly(5)- in 26 studies

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-19901 (3.85)18.7374
1990's12 (46.15)18.2507
2000's10 (38.46)29.6817
2010's2 (7.69)24.3611
2020's1 (3.85)2.80

Authors

AuthorsStudies
Pinnock, RD1
Randić, M; Rusin, KI1
Chen, L; Huang, LY1
Henderson, G; Lacey, MG1
Clements, JD; Oleskevich, S; Williams, JT1
Avoli, M; Barbarosie, M; Köhling, R; Lopantsev, V; Lücke, A; Nagao, T1
Mokha, SS; Wang, XM; Zhang, KM1
Bizon, JL; Gallagher, M; Nicolle, MM1
Mokha, SS; Wang, XM1
Martin, G; Nie, Z; Siggins, GR1
Hogenboom, F; Mulder, AH; Schoffelmeer, AN1
Budai, D; Fields, HL1
Fisone, G; Fredholm, B; Greengard, P; Lindskog, M; Svenningsson, P1
Aghajanian, GK; Jolas, T; Nestler, EJ1
Flores, CA; Long, LO; Mokha, SS; Wang, XM; Zhang, KM1
Schoffelmeer, AN; Vanderschuren, LJ; Wardeh, G1
Ackerman, TF; Bodnar, RJ; Christian, G; Echo, JA; Lamonte, N; Znamensky, V1
Commons, KG; Kow, LM; Ogawa, S; Pfaff, DW1
Bourgoin, S; Glowinski, J; Godeheu, G; Jabourian, M; Kemel, ML; Ozon, S; Pérez, S; Venance, L1
Bozsó, Z; Budai, D; Datki, Z; Farkas, T; Fülöp, L; Juhász, G; Juhász-Vedres, G; Kis, Z; Laczkó, I; Lakatos, A; Penke, B; Rózsa, E; Soós, K; Szegedi, V; Toldi, J; Tóth, G; Zarándi, M1
Deniau, JM; Ezan, P; Glowinski, J; Jabourian, M; Kemel, ML; Pérez, S1
Akaike, N; Koyama, S1
Eskridge, LL; Fairbanks, CA; Kitto, KF; Nguyen, HO; Stone, LS; Wade, CL; Wilcox, G1
Beitz, AJ; Han, HJ; Lee, JH; Roh, DH; Seo, HS; Song, S; Yoon, SY1
Bang, S; Berta, T; Chen, G; Chen, W; Gao, YJ; Ji, RR; Lay, M; Park, CK; Xie, RG; Xu, ZZ; Zhao, LX1
da Cunha, JM; Godoi, MM; Junior, HZ; Zanoveli, JM1

Other Studies

26 other study(ies) available for n-methylaspartate and enkephalin, ala(2)-mephe(4)-gly(5)-

ArticleYear
Activation of kappa-opioid receptors depresses electrically evoked excitatory postsynaptic potentials on 5-HT-sensitive neurones in the rat dorsal raphé nucleus in vitro.
    Brain research, 1992, Jun-26, Volume: 583, Issue:1-2

    Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Afferent Pathways; Animals; Benzofurans; Bicuculline; Bombesin; Cholecystokinin; Electric Stimulation; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Evoked Potentials; Glutamates; Glutamic Acid; In Vitro Techniques; Kynurenic Acid; N-Methylaspartate; Naloxone; Naltrexone; Neurons; Picrotoxin; Prazosin; Pyrrolidines; Quinoxalines; Raphe Nuclei; Rats; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu; Serotonin; Synapses; Tetrodotoxin

1992
Modulation of NMDA-induced currents by mu-opioid receptor agonist DAGO in acutely isolated rat spinal dorsal horn neurons.
    Neuroscience letters, 1991, Apr-01, Volume: 124, Issue:2

    Topics: Animals; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; In Vitro Techniques; N-Methylaspartate; Naloxone; Neurons; Neurons, Afferent; Rats; Receptors, Opioid; Receptors, Opioid, mu; Spinal Cord; Synaptic Transmission; Tetrodotoxin

1991
Sustained potentiation of NMDA receptor-mediated glutamate responses through activation of protein kinase C by a mu opioid.
    Neuron, 1991, Volume: 7, Issue:2

    Topics: Animals; Endorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Enzyme Activation; Glutamates; Glutamic Acid; Medulla Oblongata; N-Methylaspartate; Neurons; Protein Kinase C; Rats; Receptors, N-Methyl-D-Aspartate

1991
Actions of phencyclidine on rat locus coeruleus neurones in vitro.
    Neuroscience, 1986, Volume: 17, Issue:2

    Topics: Action Potentials; Animals; Aspartic Acid; Cell Count; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Evoked Potentials; Locus Coeruleus; Male; Membrane Potentials; N-Methylaspartate; Neurons; Norepinephrine; Phencyclidine; Rats; Rats, Inbred Strains; Stereoisomerism; Time Factors

1986
Opioid-glutamate interactions in rat locus coeruleus neurons.
    Journal of neurophysiology, 1993, Volume: 70, Issue:3

    Topics: Afferent Pathways; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Endorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Glutamates; Glutamic Acid; Locus Coeruleus; Male; Membrane Potentials; N-Methylaspartate; Neurons; Rats; Rats, Wistar; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid; Receptors, Opioid, mu; Synaptic Transmission

1993
Synchronous GABA-mediated potentials and epileptiform discharges in the rat limbic system in vitro.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1996, Jun-15, Volume: 16, Issue:12

    Topics: 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Analgesics; Animals; Disease Models, Animal; Electrophysiology; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Entorhinal Cortex; Epilepsy; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Hippocampus; Limbic System; Male; Membrane Potentials; N-Methylaspartate; Nerve Fibers; Piperazines; Potassium; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Serotonin Receptor Agonists

1996
Opioids modulate N-methyl-D-aspartic acid (NMDA)-evoked responses of neurons in the superficial and deeper dorsal horn of the medulla (trigeminal nucleus caudalis).
    Brain research, 1996, May-06, Volume: 719, Issue:1-2

    Topics: Analgesics, Opioid; Animals; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Evoked Potentials; Male; N-Methylaspartate; Neurons; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Receptors, Opioid, mu; Trigeminal Caudal Nucleus

1996
In vitro autoradiography of ionotropic glutamate receptors in hippocampus and striatum of aged Long-Evans rats: relationship to spatial learning.
    Neuroscience, 1996, Volume: 74, Issue:3

    Topics: Aging; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Autoradiography; Corpus Striatum; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Hippocampus; Kainic Acid; Male; Maze Learning; N-Methylaspartate; Organ Specificity; Prosencephalon; Rats; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Regression Analysis; Tritium

1996
Opioids modulate N-methyl-D-aspartic acid (NMDA)-evoked responses of trigeminothalamic neurons.
    Journal of neurophysiology, 1996, Volume: 76, Issue:3

    Topics: Analgesics; Animals; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Male; Microelectrodes; N-Methylaspartate; Naloxone; Narcotic Antagonists; Neurons; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid, delta; Receptors, Opioid, mu; Thalamus; Trigeminal Nuclei

1996
mu-Opioid receptors modulate NMDA receptor-mediated responses in nucleus accumbens neurons.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1997, Jan-01, Volume: 17, Issue:1

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Electric Stimulation; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Excitatory Amino Acid Agonists; Kainic Acid; Male; N-Methylaspartate; Neurons; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid, mu; Synapses; Synaptic Transmission

1997
Kappa1- and kappa2-opioid receptors mediating presynaptic inhibition of dopamine and acetylcholine release in rat neostriatum.
    British journal of pharmacology, 1997, Volume: 122, Issue:3

    Topics: Acetylcholine; Animals; Benzeneacetamides; Dopamine; Dynorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Ethylketocyclazocine; In Vitro Techniques; Male; N-Methylaspartate; Naloxone; Neostriatum; Neural Inhibition; Peptide Fragments; Pyrrolidines; Rats; Rats, Wistar; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu

1997
Endogenous opioid peptides acting at mu-opioid receptors in the dorsal horn contribute to midbrain modulation of spinal nociceptive neurons.
    Journal of neurophysiology, 1998, Volume: 79, Issue:2

    Topics: Adrenergic alpha-Agonists; Analgesics, Opioid; Animals; Bicuculline; Clonidine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Excitatory Amino Acid Agonists; GABA Antagonists; Hot Temperature; Iontophoresis; Kainic Acid; Male; Medulla Oblongata; N-Methylaspartate; Naloxone; Narcotic Antagonists; Nociceptors; Opioid Peptides; Pain; Peptide Fragments; Peptides; Periaqueductal Gray; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Somatostatin; Spinal Cord; Tail

1998
Mu- and delta-opioid receptor agonists inhibit DARPP-32 phosphorylation in distinct populations of striatal projection neurons.
    The European journal of neuroscience, 1999, Volume: 11, Issue:6

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Corpus Striatum; Dopamine and cAMP-Regulated Phosphoprotein 32; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; In Vitro Techniques; Male; N-Methylaspartate; Nerve Tissue Proteins; Neurons; Phosphoproteins; Phosphorylation; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Receptors, Opioid, mu

1999
Chronic morphine increases GABA tone on serotonergic neurons of the dorsal raphe nucleus: association with an up-regulation of the cyclic AMP pathway.
    Neuroscience, 2000, Volume: 95, Issue:2

    Topics: Adenylyl Cyclases; Analgesics, Opioid; Animals; Cardiovascular Agents; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Electrophysiology; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enzyme Inhibitors; Excitatory Amino Acid Agonists; gamma-Aminobutyric Acid; In Vitro Techniques; Interneurons; Isoquinolines; Male; Membrane Potentials; Morphine; N-Methylaspartate; Neural Inhibition; Periaqueductal Gray; Phenylephrine; Pyrimidines; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Serotonin; Substance Withdrawal Syndrome; Sulfonamides; Sympathomimetics; Tetrazoles; Tetrodotoxin; Thionucleotides

2000
Endomorphin-1 and endomorphin-2 modulate responses of trigeminal neurons evoked by N-methyl-D-aspartic acid and somatosensory stimuli.
    Journal of neurophysiology, 2000, Volume: 83, Issue:6

    Topics: Analgesics, Opioid; Animals; Electric Stimulation; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Excitatory Amino Acid Agonists; Iontophoresis; Male; Medulla Oblongata; N-Methylaspartate; Naloxone; Narcotic Antagonists; Neurons; Nociceptors; Oligopeptides; Physical Stimulation; Rats; Rats, Sprague-Dawley; Trigeminal Nerve

2000
Morphine acutely and persistently attenuates nonvesicular GABA release in rat nucleus accumbens.
    Synapse (New York, N.Y.), 2001, Volume: 42, Issue:2

    Topics: Analgesics; Animals; Benzeneacetamides; Carrier Proteins; Dopamine; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Excitatory Amino Acid Agonists; gamma-Aminobutyric Acid; Male; Morphine; Morphine Dependence; N-Methylaspartate; Naloxone; Neural Inhibition; Neurons; Nucleus Accumbens; Organ Culture Techniques; Pyrrolidines; Rats; Rats, Wistar; Receptors, Dopamine D1; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid, mu; Substance Withdrawal Syndrome; Tritium

2001
Excitatory amino acid receptor subtype agonists induce feeding in the nucleus accumbens shell in rats: opioid antagonist actions and interactions with mu-opioid agonists.
    Brain research, 2001, Dec-07, Volume: 921, Issue:1-2

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analgesics, Opioid; Animals; Dose-Response Relationship, Drug; Drug Interactions; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Excitatory Amino Acid Agonists; Feeding Behavior; Male; N-Methylaspartate; Naltrexone; Narcotic Antagonists; Neurons; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid, mu; Synaptic Transmission

2001
Potentiation of the excitatory action of NMDA in ventrolateral periaqueductal gray by the mu-opioid receptor agonist, DAMGO.
    Brain research, 2002, May-10, Volume: 935, Issue:1-2

    Topics: Action Potentials; Analgesics, Opioid; Animals; Dose-Response Relationship, Drug; Drug Interactions; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Methionine; Enzyme Inhibitors; Ethylmaleimide; Female; Male; N-Methylaspartate; Naltrexone; Narcotic Antagonists; Neural Inhibition; Neural Pathways; Neurons; Organ Culture Techniques; Periaqueductal Gray; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid, mu; Synaptic Transmission

2002
Functional mu opioid receptors are expressed in cholinergic interneurons of the rat dorsal striatum: territorial specificity and diurnal variation.
    The European journal of neuroscience, 2005, Volume: 21, Issue:12

    Topics: Acetylcholine; Analgesics, Opioid; Animals; Blotting, Northern; Choline O-Acetyltransferase; Circadian Rhythm; Corpus Striatum; Drug Interactions; Electric Stimulation; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Excitatory Amino Acid Agonists; Immunohistochemistry; In Vitro Techniques; Interneurons; Limbic System; Membrane Potentials; N-Methylaspartate; Naltrexone; Narcotic Antagonists; Patch-Clamp Techniques; Potassium; Protein Precursors; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Synaptosomes; Tritium

2005
Endomorphin-2, an endogenous tetrapeptide, protects against Abeta1-42 in vitro and in vivo.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2006, Volume: 20, Issue:8

    Topics: Amyloid beta-Peptides; Animals; Cell Line, Tumor; Cell Survival; Cells, Cultured; Circular Dichroism; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Evoked Potentials; Excitatory Postsynaptic Potentials; Iontophoresis; Light; Microscopy, Electron, Transmission; N-Methylaspartate; Neurons; Neuroprotective Agents; Oligopeptides; Peptide Fragments; Radioligand Assay; Rats; Rats, Wistar; Scattering, Radiation

2006
Impact of 6-hydroxydopamine lesions and cocaine exposure on mu-opioid receptor expression and regulation of cholinergic transmission in the limbic-prefrontal territory of the rat dorsal striatum.
    The European journal of neuroscience, 2007, Volume: 25, Issue:5

    Topics: Acetylcholine; Animals; Behavior, Animal; Brain Injuries; Circadian Rhythm; Cocaine; Corpus Striatum; Dopamine Uptake Inhibitors; Drug Administration Schedule; Drug Interactions; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Excitatory Amino Acid Agonists; Functional Laterality; Male; Models, Neurological; N-Methylaspartate; Oxidopamine; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Tritium

2007
Activation of mu-opioid receptor selectively potentiates NMDA-induced outward currents in rat locus coeruleus neurons.
    Neuroscience research, 2008, Volume: 60, Issue:1

    Topics: Action Potentials; Analgesics, Opioid; Animals; Dose-Response Relationship, Drug; Drug Synergism; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Glutamic Acid; Locus Coeruleus; N-Methylaspartate; Narcotic Antagonists; Neural Inhibition; Organ Culture Techniques; Patch-Clamp Techniques; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid, mu; Synaptic Transmission

2008
Immunoneutralization of agmatine sensitizes mice to micro-opioid receptor tolerance.
    The Journal of pharmacology and experimental therapeutics, 2009, Volume: 331, Issue:2

    Topics: Agmatine; Analgesics, Opioid; Animals; Antibodies, Blocking; Arginine; Behavior, Animal; Dose-Response Relationship, Drug; Drug Tolerance; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Excitatory Amino Acid Agonists; Guinea Pigs; Immunoglobulin G; Immunohistochemistry; Injections, Spinal; Male; Mice; N-Methylaspartate; Oligopeptides; Pain Measurement; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Spinal Cord

2009
Activation of spinal alpha-2 adrenoceptors, but not mu-opioid receptors, reduces the intrathecal N-methyl-D-aspartate-induced increase in spinal NR1 subunit phosphorylation and nociceptive behaviors in the rat.
    Anesthesia and analgesia, 2010, Feb-01, Volume: 110, Issue:2

    Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Analgesics; Animals; Behavior, Animal; Clonidine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Immunohistochemistry; Injections, Spinal; Male; N-Methylaspartate; Pain; Phosphorylation; Posterior Horn Cells; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid, mu

2010
β-arrestin-2 regulates NMDA receptor function in spinal lamina II neurons and duration of persistent pain.
    Nature communications, 2016, 08-19, Volume: 7

    Topics: Analgesics, Opioid; Animals; beta-Arrestin 2; Chronic Pain; Disease Models, Animal; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Humans; Hyperalgesia; Injections, Spinal; Male; Mice; Mice, Inbred ICR; Mice, Knockout; N-Methylaspartate; Neuralgia; Neurons; Peripheral Nerve Injuries; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid, mu; Spinal Cord Dorsal Horn; Substantia Gelatinosa; Time Factors

2016
Mu-opioid and CB1 cannabinoid receptors of the dorsal periaqueductal gray interplay in the regulation of fear response, but not antinociception.
    Pharmacology, biochemistry, and behavior, 2020, Volume: 194

    Topics: Analgesics, Opioid; Animals; Arachidonic Acids; Behavior, Animal; Cannabinoid Receptor Agonists; Cannabinoid Receptor Antagonists; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Excitatory Amino Acid Agonists; Fear; Freezing Reaction, Cataleptic; Male; Microinjections; N-Methylaspartate; Nociception; Pain; Pain Measurement; Periaqueductal Gray; Piperidines; Pyrazoles; Rats; Receptor, Cannabinoid, CB1; Receptors, Opioid, mu; Somatostatin

2020