Compounds > n-methylaspartate
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n-methylaspartate and eliprodil

n-methylaspartate has been researched along with eliprodil in 17 studies

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19902 (11.76)18.7374
1990's14 (82.35)18.2507
2000's1 (5.88)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Butler, TW; Chenard, BL; Prochniak, MA; Shalaby, IA1
Harms, J; Woodward, JJ1
Duval, D; Gauffeny, C; Nowicki, JP; Roome, N; Scatton, B1
Heikkila, RE; Riordan, DE; Sonsalla, PK1
Carter, CJ; Lloyd, KG; Scatton, B; Zivkovic, B1
Benavides, J; Gotti, B; MacKenzie, ET; Scatton, B1
Bertin, J; Carter, C; Dupont, R; Duverger, D; Frost, J; Gaudilliere, B; Gotti, B; MacKenzie, ET; Rousseau, J; Scatton, B1
Arbilla, S; Benavides, J; Carter, C; Legendre, P; Lloyd, KG; MacKenzie, ET; Noel, F; Thuret, F; Vincent, JD; Zivkovic, B1
Carter, C; Fage, D; Nankai, M1
Balster, RL; Nicholson, KL; Sanger, DJ1
Carter, C; Fage, D; Klarica, M; Nankai, M1
Camarasa, J; Camins, A; Escubedo, E; Gabriel, C; Pallàs, M; Sureda, FX1
Kapin, MA; Opitz, T; Reyes, A; Reyes, M; Stanton, PK1
DeSantis, L; Kapin, MA; Nawy, S; Pang, IH; Wexler, EM1
Chandler, ML; DeSantis, LM; Doshi, R; Kapin, MA; Scatton, B1
Sharif, NA; Xu, SX1
Cebere, A; Cebers, G; Liljequist, S; Wägner, A1

Other Studies

17 other study(ies) available for n-methylaspartate and eliprodil

ArticleYear
Neuroprotective effects of the N-methyl-D-aspartate receptor antagonists ifenprodil and SL-82,0715 on hippocampal cells in culture.
    The Journal of pharmacology and experimental therapeutics, 1992, Volume: 260, Issue:2

    Topics: Animals; Cells, Cultured; Culture Media; Dizocilpine Maleate; Drug Antagonism; Glutamates; Glutamic Acid; Hippocampus; L-Lactate Dehydrogenase; N-Methylaspartate; Piperidines; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter

1992
The putative polyamine antagonists ifenprodil and SL 82.0715 enhance dopamine efflux from rat striatal slices independent of NMDA receptor activation.
    European journal of pharmacology, 1992, Jan-21, Volume: 210, Issue:3

    Topics: Adrenergic alpha-Antagonists; Animals; Brain; Cocaine; Dopamine; Male; N-Methylaspartate; Norepinephrine; Piperidines; Polyamines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate

1992
SL 82.0715, an NMDA antagonist acting at the polyamine site, does not induce neurotoxic effects on rat cortical neurons.
    Neuroscience letters, 1992, Mar-30, Volume: 137, Issue:2

    Topics: Animals; Biogenic Polyamines; Cerebral Cortex; Cytoplasm; Dizocilpine Maleate; In Vitro Techniques; Male; Microscopy, Electron; N-Methylaspartate; Neurons; Piperidines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Vacuoles

1992
Competitive and noncompetitive antagonists at N-methyl-D-aspartate receptors protect against methamphetamine-induced dopaminergic damage in mice.
    The Journal of pharmacology and experimental therapeutics, 1991, Volume: 256, Issue:2

    Topics: Amino Acids; Animals; Corpus Striatum; Dizocilpine Maleate; Male; Methamphetamine; Mice; N-Methylaspartate; Pipecolic Acids; Piperidines; Receptors, Dopamine; Receptors, N-Methyl-D-Aspartate; Tyrosine 3-Monooxygenase

1991
Ifenprodil and SL 82.0715 as cerebral antiischemic agents. III. Evidence for antagonistic effects at the polyamine modulatory site within the N-methyl-D-aspartate receptor complex.
    The Journal of pharmacology and experimental therapeutics, 1990, Volume: 253, Issue:2

    Topics: Adrenergic alpha-Antagonists; Animals; Aspartic Acid; Binding Sites; Binding, Competitive; Brain; Cells, Cultured; Drug Interactions; Female; Glycine; Male; N-Methylaspartate; Phencyclidine; Piperidines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Spermidine; Spermine; Spinal Cord

1990
The pharmacotherapy of focal cortical ischaemia in the mouse.
    Brain research, 1990, Jul-09, Volume: 522, Issue:2

    Topics: Animals; Calcium Channel Blockers; Cell Survival; Cyclandelate; Ischemic Attack, Transient; Male; Mice; Molecular Structure; N-Methylaspartate; Piperidines; Platelet Activating Factor; Receptors, GABA-A; Receptors, Opioid; Receptors, sigma; Vincamine

1990
Ifenprodil and SL 82.0715 as cerebral anti-ischemic agents. I. Evidence for efficacy in models of focal cerebral ischemia.
    The Journal of pharmacology and experimental therapeutics, 1988, Volume: 247, Issue:3

    Topics: Animals; Aspartic Acid; Brain Ischemia; Cats; Female; Male; Models, Cardiovascular; N-Methylaspartate; Phencyclidine; Piperidines; Rats; Rats, Inbred F344; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Vasoconstriction

1988
Ifenprodil and SL 82.0715 as cerebral anti-ischemic agents. II. Evidence for N-methyl-D-aspartate receptor antagonist properties.
    The Journal of pharmacology and experimental therapeutics, 1988, Volume: 247, Issue:3

    Topics: Animals; Aspartic Acid; Brain Ischemia; Cells, Cultured; Cerebellum; Corpus Striatum; Cyclic GMP; Dopamine; Harmaline; In Vitro Techniques; Mice; N-Methylaspartate; Phencyclidine; Piperazines; Piperidines; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Spinal Cord

1988
NMDA receptor subtype selectivity: eliprodil, polyamine spider toxins, dextromethorphan, and desipramine selectively block NMDA-evoked striatal acetylcholine but not spermidine release.
    Journal of neurochemistry, 1995, Volume: 64, Issue:5

    Topics: Acetylcholine; Animals; Corpus Striatum; Desipramine; Dextromethorphan; Indoleacetic Acids; N-Methylaspartate; Phenols; Phenylacetates; Piperidines; Polyamines; Rats; Receptors, N-Methyl-D-Aspartate; Spermidine; Spider Venoms

1995
Evaluation of the reinforcing effects of eliprodil in rhesus monkeys and its discriminative stimulus effects in rats.
    Drug and alcohol dependence, 1994, Volume: 35, Issue:3

    Topics: Animals; Appetitive Behavior; Brain; Discrimination Learning; Dizocilpine Maleate; Dose-Response Relationship, Drug; Female; Injections, Intravenous; Macaca mulatta; Male; Motivation; N-Methylaspartate; Phencyclidine; Piperidines; Rats; Rats, Wistar; Reinforcement Schedule; Self Administration

1994
Evidence for native NMDA receptor subtype pharmacology as revealed by differential effects on the NMDA-evoked release of striatal neuromodulators: eliprodil, ifenprodil and other native NMDA receptor subtype selective compounds.
    Neurochemistry international, 1996, Volume: 29, Issue:5

    Topics: Animals; Calcium Channel Blockers; Corpus Striatum; Dantrolene; Excitatory Amino Acid Antagonists; In Vitro Techniques; N-Methylaspartate; Neurotransmitter Agents; Piperidines; Radioligand Assay; Rats; Receptors, N-Methyl-D-Aspartate; Sodium Channel Blockers; Tetrodotoxin

1996
Modulation of neuronal mitochondrial membrane potential by the NMDA receptor: role of arachidonic acid.
    Brain research, 1997, Nov-28, Volume: 777, Issue:1-2

    Topics: 2-Amino-5-phosphonovalerate; Anesthetics, Local; Animals; Arachidonic Acid; Biomarkers; Cells, Cultured; Cerebellum; Dibucaine; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Flow Cytometry; Fluorescent Dyes; Glycine; Intracellular Membranes; Kynurenic Acid; Membrane Potentials; Mitochondria; N-Methylaspartate; Piperidines; Quinacrine; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Rhodamine 123; Rhodamines; Sulfonamides

1997
Eliprodil, a non-competitive, NR2B-selective NMDA antagonist, protects pyramidal neurons in hippocampal slices from hypoxic/ischemic damage.
    Brain research, 1998, Jan-26, Volume: 782, Issue:1-2

    Topics: Animals; Excitatory Amino Acid Antagonists; Hippocampus; Hypoxia; In Vitro Techniques; Ischemia; Male; N-Methylaspartate; Neuroprotective Agents; Piperidines; Pyramidal Cells; Rats; Rats, Sprague-Dawley

1998
Protection by eliprodil against excitotoxicity in cultured rat retinal ganglion cells.
    Investigative ophthalmology & visual science, 1999, Volume: 40, Issue:6

    Topics: Animals; Cell Death; Cells, Cultured; Drug Combinations; Electric Conductivity; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Glycine; Male; N-Methylaspartate; Neuroprotective Agents; Piperidines; Rats; Rats, Sprague-Dawley; Retinal Ganglion Cells

1999
Neuroprotective effects of eliprodil in retinal excitotoxicity and ischemia.
    Investigative ophthalmology & visual science, 1999, Volume: 40, Issue:6

    Topics: Animals; Choline O-Acetyltransferase; Electroretinography; Injections; Injections, Intraperitoneal; Ischemia; N-Methylaspartate; Neuroprotective Agents; Neurotoxins; Piperidines; Rats; Rats, Long-Evans; Retina; Retinal Ganglion Cells; Retinal Vessels; Vitreous Body

1999
Human retina contains polyamine sensitive [3H]-ifenprodil binding sites: implications for neuroprotection?
    The British journal of ophthalmology, 1999, Volume: 83, Issue:2

    Topics: Aged; Aged, 80 and over; Biguanides; Binding Sites; Excitatory Amino Acid Antagonists; Humans; N-Methylaspartate; Neuroprotective Agents; Piperidines; Polyamines; Receptors, N-Methyl-D-Aspartate; Retina

1999
Spermidine attenuates the inhibitory effect of ethanol on NMDA-induced neurotoxicity.
    Naunyn-Schmiedeberg's archives of pharmacology, 2002, Volume: 366, Issue:2

    Topics: Analysis of Variance; Animals; Cell Survival; Cells, Cultured; Cerebellum; Dose-Response Relationship, Drug; Drug Interactions; Ethanol; N-Methylaspartate; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Spermidine

2002