n-methylaspartate has been researched along with dextrorphan in 28 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (32.14) | 18.7374 |
| 1990's | 17 (60.71) | 18.2507 |
| 2000's | 1 (3.57) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (3.57) | 2.80 |
| Authors | Studies |
|---|---|
| Faden, AI; Panter, SS | 1 |
| Bakshi, R; Faden, AI; Ni, RX | 1 |
| Fujiwara, M; Iwasaki, K; Mine, K; Okada, M; Urae, A | 1 |
| Ohno, M; Ueki, S; Watanabe, S; Yamamoto, T | 1 |
| Choi, DW; Regan, RF | 1 |
| Lo, EH; Steinberg, GK; Sun, GH | 1 |
| DeLaPaz, R; Kunis, D; Saleh, J; Steinberg, GK | 1 |
| Demediuk, P; Faden, AI; Panter, SS; Vink, R | 1 |
| Choi, DW; Goldberg, MP; Monyer, H; Tecoma, ES | 1 |
| Aryanpur, JJ; Cole, AE; Eccles, CU; Fisher, RS | 1 |
| DeLaPaz, R; Kunis, D; Saleh, J; Steinberg, GK; Zarnegar, SR | 2 |
| Choi, DW; Coulter, DA; Prince, DA; Wong, BY | 1 |
| Berry, SC; Church, J; Lodge, D | 1 |
| Choi, DW; Peters, S; Viseskul, V | 1 |
| Kunis, D; Saleh, J; Steinberg, GK | 1 |
| Grant, GA; Kunis, DM; Maier, CM; Steinberg, GK; Sun, GH; Yoon, EJ | 1 |
| Akaike, N; Himori, N; Imai, M; Kurasawa, M; Matsukura, T; Mishima, K; Tanaka, Y; Ueno, K; Watanabe, H | 1 |
| Hargreaves, RJ; Hill, RG; Iversen, LL | 1 |
| Gruner, R; Lodge, D; Millar, J; Parsons, CG; Rozental, J | 1 |
| Chen, J; Graham, SH; Simon, RP | 1 |
| Choi, DW; Corbett, JA; Hewett, SJ; McDaniel, ML | 1 |
| Anderson, DK; Farooqui, AA; Horrocks, LA | 1 |
| Dickenson, AH | 1 |
| Arnold, GL; Griebel, ML; Kearns, GL; Koroma, DM; Valentine, JL | 1 |
| Choi, DW; Hsu, CY; Jacquin, MF; Kanellopoulos, GK; Kato, H; Kouchoukos, NT; Matsuo, S; Wu, YJ | 1 |
| Carlsson, C; Chen, D; Harakal, C; Kamel, IR; Wendling, KS; Wendling, WW | 1 |
| Cerne, R; Izenwasser, S; Newman, AH; Smith, JL; Tortella, FC; Witkin, JM | 1 |
2 review(s) available for n-methylaspartate and dextrorphan
| Article | Year |
|---|---|
Neuroprotective NMDA antagonists: the controversy over their potential for adverse effects on cortical neuronal morphology.
Topics: Animals; Cell Survival; Cerebral Cortex; Dextrorphan; Dizocilpine Maleate; Dose-Response Relationship, Drug; Energy Metabolism; Excitatory Amino Acid Antagonists; Glycine; Gyrus Cinguli; Ketamine; N-Methylaspartate; Neurons; Phencyclidine; Rats; Receptors, N-Methyl-D-Aspartate; Vacuoles | 1994 |
Neurophysiology of opioid poorly responsive pain.
Topics: Analgesics, Opioid; Animals; Central Nervous System; Clonidine; Dextromethorphan; Dextrorphan; Dynorphins; Humans; Morphine; N-Methylaspartate; Neoplasms; Neurophysiology; Neuroprotective Agents; Pain; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid; Sympatholytics | 1994 |
26 other study(ies) available for n-methylaspartate and dextrorphan
| Article | Year |
|---|---|
Pretreatment with NMDA antagonists limits release of excitatory amino acids following traumatic brain injury.
Topics: Amino Acids; Animals; Brain Injuries; Chromatography, High Pressure Liquid; Dextrorphan; Dialysis; Glutamates; Glutamic Acid; Male; N-Methylaspartate; Pipecolic Acids; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate | 1992 |
N-methyl-D-aspartate (NMDA) and opioid receptors mediate dynorphin-induced spinal cord injury: behavioral and histological studies.
Topics: Animals; Dextrorphan; Dynorphins; Glial Fibrillary Acidic Protein; Immunohistochemistry; Infusions, Parenteral; Male; Motor Activity; N-Methylaspartate; Naltrexone; Narcotic Antagonists; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, kappa; Serotonin; Silver Staining; Spinal Cord; Staining and Labeling | 1992 |
Effects of the N-methyl-D-aspartate antagonists on the rise in [Ca2+]i following depolarization in aged rat brain synaptosomes.
Topics: Aging; Animals; Brain; Calcium; Dextrorphan; Dizocilpine Maleate; Fluorescent Dyes; Heterocyclic Compounds, 3-Ring; Magnesium; Male; Membrane Potentials; N-Methylaspartate; Potassium; Rats; Rats, Inbred F344; Receptors, N-Methyl-D-Aspartate; Spectrometry, Fluorescence; Synaptosomes; Time Factors | 1992 |
Protection by N-methyl-D-aspartate receptor antagonists against impairment of working memory in rats following transient cerebral ischemia.
Topics: Animals; Dextrorphan; Dizocilpine Maleate; Ischemic Attack, Transient; Memory; N-Methylaspartate; Pipecolic Acids; Prosencephalon; Rats; Receptors, N-Methyl-D-Aspartate | 1992 |
Glutamate neurotoxicity in spinal cord cell culture.
Topics: Animals; Cells, Cultured; Dextromethorphan; Dextrorphan; Glutamates; Glutamic Acid; Glycine; N-Methylaspartate; Neurons; Spinal Cord | 1991 |
Effects of NMDA and calcium channel antagonists on regional cerebral blood flow.
Topics: Animals; Blood Pressure; Calcium Channel Blockers; Cerebral Cortex; Cerebrovascular Circulation; Dextromethorphan; Dextrorphan; Dizocilpine Maleate; Heart Rate; Ketamine; Mesencephalon; N-Methylaspartate; Nimodipine; Rabbits; Reference Values; Regional Blood Flow; Rhombencephalon | 1991 |
Protection after transient focal cerebral ischemia by the N-methyl-D-aspartate antagonist dextrorphan is dependent upon plasma and brain levels.
Topics: Animals; Brain; Dextrorphan; Dose-Response Relationship, Drug; Ischemic Attack, Transient; Magnetic Resonance Imaging; Male; N-Methylaspartate; Nervous System Diseases; Rabbits | 1991 |
The role of excitatory amino acids and NMDA receptors in traumatic brain injury.
Topics: Animals; Aspartic Acid; Binding, Competitive; Brain; Brain Injuries; Dextrorphan; Glutamates; Glutamic Acid; Magnesium; Magnetic Resonance Spectroscopy; Male; N-Methylaspartate; Phosphates; Phosphocreatine; Piperazines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1989 |
Traumatic neuronal injury in vitro is attenuated by NMDA antagonists.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Cell Survival; Cells, Cultured; Cerebral Cortex; Dextrorphan; Mice; Morphinans; N-Methylaspartate; Nerve Tissue; Neuroglia; Neurons; Stress, Mechanical | 1989 |
Selective depression of N-methyl-D-aspartate-mediated responses by dextrorphan in the hippocampal slice in rat.
Topics: Animals; Anticonvulsants; Aspartic Acid; Dextrorphan; Dibenzocycloheptenes; Dizocilpine Maleate; Dose-Response Relationship, Drug; Evoked Potentials; Hippocampus; In Vitro Techniques; Magnesium; Male; Morphinans; N-Methylaspartate; Neurons; Oxadiazoles; Quisqualic Acid; Rats; Rats, Inbred Strains | 1989 |
Protective effect of N-methyl-D-aspartate antagonists after focal cerebral ischemia in rabbits.
Topics: Animals; Aspartic Acid; Cerebral Cortex; Corpus Striatum; Dextromethorphan; Dextrorphan; Ischemic Attack, Transient; Levorphanol; Magnetic Resonance Imaging; Male; Morphinans; N-Methylaspartate; Neurons; Rabbits | 1989 |
Pretreatment with the NMDA antagonist dextrorphan reduces cerebral injury following transient focal ischemia in rabbits.
Topics: Animals; Aspartic Acid; Brain; Brain Edema; Cerebral Cortex; Dextrorphan; Ischemic Attack, Transient; Magnetic Resonance Spectroscopy; Male; Morphinans; N-Methylaspartate; Neurons; Rabbits | 1989 |
Dextrorphan and dextromethorphan, common antitussives, are antiepileptic and antagonize N-methyl-D-aspartate in brain slices.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Antitussive Agents; Aspartic Acid; Cerebral Cortex; Dextromethorphan; Dextrorphan; Evoked Potentials; Guinea Pigs; In Vitro Techniques; Levorphanol; Morphinans; N-Methylaspartate; Seizures; Valine | 1988 |
Differential effects of dextrorphan and levorphanol on the excitation of rat spinal neurons by amino acids.
Topics: Acetylcholine; Amino Acids; Animals; Aspartic Acid; Dextrorphan; Ketamine; Levorphanol; Morphinans; N-Methylaspartate; Neurons; Phencyclidine; Rats; Receptors, Opioid; Receptors, sigma; Spinal Cord | 1985 |
Dextrorphan and levorphanol selectively block N-methyl-D-aspartate receptor-mediated neurotoxicity on cortical neurons.
Topics: Animals; Aspartic Acid; Cell Survival; Cells, Cultured; Cerebral Cortex; Dextrorphan; Kainic Acid; Levorphanol; Mice; Morphinans; N-Methylaspartate; Neurons; Neurotoxins; Quinolinic Acid; Quinolinic Acids; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1987 |
Delayed treatment with dextromethorphan and dextrorphan reduces cerebral damage after transient focal ischemia.
Topics: Animals; Aspartic Acid; Brain Ischemia; Dextromethorphan; Dextrorphan; Levorphanol; Male; Morphinans; N-Methylaspartate; Rabbits | 1988 |
Neuroprotection by N-methyl-D-aspartate antagonists in focal cerebral ischemia is dependent on continued maintenance dosing.
Topics: Animals; Body Temperature; Brain Edema; Brain Ischemia; Cerebral Cortex; Corpus Striatum; Dextromethorphan; Dextrorphan; Hydrogen-Ion Concentration; N-Methylaspartate; Neuroprotective Agents; Oxygen; Rabbits | 1995 |
Dextrorphan attenuates the behavioral consequences of ischemia and the biochemical consequences of anoxia: possible role of N-methyl-d-aspartate receptor antagonism and ATP replenishing action in its cerebroprotecting profile.
Topics: Adenosine Triphosphate; Adenylyl Cyclases; Animals; Avoidance Learning; Behavior, Animal; Brain Ischemia; Dextrorphan; Dizocilpine Maleate; Exploratory Behavior; Hypoxia, Brain; Injections, Intraventricular; Male; Maze Learning; Mice; Mice, Inbred ICR; Mice, Inbred Strains; N-Methylaspartate; Nerve Degeneration; Oxidative Phosphorylation; Postural Balance; Potassium Cyanide; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate | 1993 |
Patch clamp studies on the kinetics and selectivity of N-methyl-D-aspartate receptor antagonism by memantine (1-amino-3,5-dimethyladamantan).
Topics: Animals; Cells, Cultured; Dextrorphan; Dizocilpine Maleate; Dose-Response Relationship, Drug; Embryo, Mammalian; gamma-Aminobutyric Acid; Glycine; Hippocampus; Ketamine; Kinetics; Magnesium; Memantine; Membrane Potentials; N-Methylaspartate; Neurons; Phencyclidine; Rats; Receptors, N-Methyl-D-Aspartate; Superior Colliculi | 1993 |
A dose-response study of dextrorphan in permanent focal ischemia.
Topics: Analysis of Variance; Animals; Basal Ganglia; Blood Gas Analysis; Blood Pressure; Brain Ischemia; Cerebral Arteries; Cerebral Infarction; Dextrorphan; Dose-Response Relationship, Drug; N-Methylaspartate; Rats | 1993 |
Inhibition of nitric oxide formation does not protect murine cortical cell cultures from N-methyl-D-aspartate neurotoxicity.
Topics: Animals; Arginine; Cell Death; Cells, Cultured; Cerebral Cortex; Cyclic GMP; Dextrorphan; Mice; N-Methylaspartate; Nitric Oxide; Nitroarginine; omega-N-Methylarginine; Rats | 1993 |
Effect of glutamate and its analogs on diacylglycerol and monoacylglycerol lipase activities of neuron-enriched cultures.
Topics: Animals; Cells, Cultured; Dextrorphan; Dizocilpine Maleate; Dose-Response Relationship, Drug; Embryo, Mammalian; Glutamates; Kinetics; Lipoprotein Lipase; Mice; Mice, Inbred Strains; Monoacylglycerol Lipases; N-Methylaspartate; Neurons; Spinal Cord | 1993 |
Dextromethorphan in nonketotic hyperglycinaemia: metabolic variation confounds the dose-response relationship.
Topics: Child; Dextromethorphan; Dextrorphan; Dose-Response Relationship, Drug; Female; Humans; Hyperglycemic Hyperosmolar Nonketotic Coma; Infant, Newborn; N-Methylaspartate; Seizures | 1997 |
Protection of rat spinal cord from ischemia with dextrorphan and cycloheximide: effects on necrosis and apoptosis.
Topics: Animals; Apoptosis; Cycloheximide; Dextrorphan; Excitatory Amino Acid Antagonists; Male; Microscopy, Electron; N-Methylaspartate; Necrosis; Neurons; Paraplegia; Premedication; Protein Synthesis Inhibitors; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Reperfusion Injury; Spinal Cord; Time Factors | 1997 |
N-methyl-D-aspartate (NMDA) antagonists--S(+)-ketamine, dextrorphan, and dextromethorphan--act as calcium antagonists on bovine cerebral arteries.
Topics: Animals; Calcium; Calcium Channel Blockers; Calcium Radioisotopes; Cattle; Dextromethorphan; Dextrorphan; Dose-Response Relationship, Drug; Electric Stimulation; Excitatory Amino Acid Agonists; In Vitro Techniques; Isometric Contraction; Ketamine; Middle Cerebral Artery; Muscle Tonus; Muscle, Smooth, Vascular; N-Methylaspartate; Nimodipine; Vascular Resistance; Vasoconstrictor Agents | 2008 |
N-Substituted-3-alkoxy-derivatives of dextromethorphan are functional NMDA receptor antagonists in vivo: Evidence from an NMDA-induced seizure model in rats.
Topics: Alcohols; Animals; Anticonvulsants; Binding Sites; Dextromethorphan; Dextrorphan; Disease Models, Animal; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Infusions, Intraventricular; Ligands; Male; N-Methylaspartate; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Receptors, sigma; Seizures; Sigma-1 Receptor; Treatment Outcome | 2021 |