n-methylaspartate has been researched along with cyclic gmp in 205 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 25 (12.20) | 18.7374 |
| 1990's | 111 (54.15) | 18.2507 |
| 2000's | 49 (23.90) | 29.6817 |
| 2010's | 15 (7.32) | 24.3611 |
| 2020's | 5 (2.44) | 2.80 |
| Authors | Studies |
|---|---|
| Bockaert, J; Desagher, S; Deshager, S; Fagni, L; Manzoni, O; Marin, P; Prezeau, L | 1 |
| Costa, E; Kiedrowski, L; Wroblewski, JT | 3 |
| Boje, KM; Skolnick, P | 1 |
| Li, M; Ryan, R; Wood, PL | 2 |
| Boje, K; Maccecchini, ML; Miller, R; Pennington, M; Skolnick, P | 1 |
| Cler, JA; Garland, DJ; Hood, WF; Iyengar, S; Mick, SJ; Monahan, JB; Rao, TS; Sun, ET; Vazquez, ML | 1 |
| Andersen, CF; Frandsen, A; Schousboe, A | 1 |
| Braid, DJ; Garthwaite, J; Morris, R; Southam, E | 1 |
| Matsuda, Y; Nonaka, H; Nozawa, M; Toki, S; Tsukuda, E; Yoshida, M | 1 |
| East, SJ; Garthwaite, J | 2 |
| Bredt, DS; Dawson, TM; Dawson, VL; London, ED; Snyder, SH | 1 |
| Baron, BM; Edwards, ML; Reynolds, IJ | 1 |
| Bermudez, J; Chang, XY; Morgan, WW | 1 |
| Barzizza, A; Maura, G; Raiteri, M | 1 |
| Garthwaite, J; Southam, E | 1 |
| Braquet, P; Chabrier, PE; Demerlé-Pallardy, C; Lonchampt, MO | 1 |
| Baron, BM; Cheng, HC; Doherty, NS; Lambert, LE; McDonald, IA; Whitten, JP | 1 |
| Cler, JA; Contreras, PC; Dilworth, VM; Iyengar, S; Mick, SJ; Monahan, JB; Rao, TS; Wood, PL | 1 |
| Cler, JA; Contreras, PC; Emmett, MR; Farah, JM; Iyengar, S; Mick, SJ; Rao, TS; Wood, PL | 1 |
| Baron, BM; McDonald, IA; Miller, F; Muench, D; White, HS; Whitten, JP | 1 |
| Buso, M; Facci, L; Leon, A; Milani, D; Skaper, SD; Toffano, G | 1 |
| Cler, J; Emmett, MR; Iyengar, S; Mick, S; Oei, E; Rao, TS; Wood, PL | 1 |
| Cruz, LJ; Gullak, MF; Mena, EE; Olivera, BM; Pagnozzi, MJ; Richter, KE; Rivier, J | 1 |
| Brooker, G; Costa, E; Danysz, W; Wroblewski, JT | 1 |
| Hoffman, PL; Moses, F; Rabe, CS; Tabakoff, B | 1 |
| Baron, BM; Dudley, MW; McCarty, DR; Miller, FP; Reynolds, IJ; Schmidt, CJ | 1 |
| Rao, TS; Wood, PL | 1 |
| Cler, J; Emmett, MR; Iyengar, S; Mick, S; Rao, TS; Wood, PL | 1 |
| McCaslin, PP; Morgan, WW | 5 |
| Bredt, DS; Snyder, SH | 1 |
| Cheney, DL; Lehmann, J; McPherson, SE; Steel, D; Wood, PL | 1 |
| Carter, CJ; Noel, F; Scatton, B | 2 |
| Chapman, AG; Hutchison, A; Lehmann, J; Meldrum, BS; Tsai, C; Wood, PL | 1 |
| Arbilla, S; Benavides, J; Carter, C; Legendre, P; Lloyd, KG; MacKenzie, ET; Noel, F; Thuret, F; Vincent, JD; Zivkovic, B | 1 |
| Carter, C; Noel, F; Scatton, B | 1 |
| Canning, HM; Leach, MJ; Marden, CM | 1 |
| Garthwaite, G; Garthwaite, J | 1 |
| Bennett, DA; Bernard, P; Boehm, C; Lehmann, J; McPherson, S; Murphy, DE; Pastor, G; Schneider, J; Steel, DJ; Tsai, C | 1 |
| Anand, H; Badman, G; Collins, JF; Dixon, AJ; Roberts, PJ | 1 |
| Foster, GA; Roberts, PJ | 1 |
| Garthwaite, J | 1 |
| Coyle, JT; Ferkany, JW; Zaczek, R | 1 |
| Burgal, M; Grisolía, S; Jordá, A; Lizondo, J | 1 |
| Cai, Z; Hersey, K; Rhodes, PG; Sigrest, T | 1 |
| Colasanti, M; Lauro, GM; Mollace, V; Nistico, G; Rodino, P; Rotiroti, D | 1 |
| Raiteri, M; Vallebuona, F | 3 |
| Bockaert, J; Culcasi, M; Gaven, F; Lafon-Cazal, M; Pietri, S | 1 |
| Patel, J; Pullan, LM; Stumpo, RJ; Thompson, C; Zinkand, WC | 1 |
| Emmett, MR; Wood, JA; Wood, PL | 1 |
| Nicklas, WJ; Zeevalk, GD | 1 |
| Bockaert, J; Culcasi, M; Lafon-Cazal, M; Pietri, S | 1 |
| de Vente, J; Garthwaite, J; Gittins, SR; Morris, R; Southam, E | 1 |
| Cummings, JA; Malenka, RC; Nicola, SM | 1 |
| Kakuyama, M; Miyawaki, I; Mori, K; Nakamura, K; Terasako, K; Toda, H | 1 |
| Bockaert, J; Fagni, L; Lafon-Cazal, M; Quignard, JF; Rodriguez, J | 1 |
| Stout, AK; Woodward, JJ | 1 |
| Acuña, C; Cudeiro, J; Grieve, KL; Martínez-Conde, S; Rivadulla, C; Rodríguez, R | 2 |
| Bockaert, J; Fagni, L; Lafon-Cazal, M; Lerner-Natoli, M; Manzoni, O; Rondouin, G | 1 |
| Boulton, CL; Garthwaite, J; Mayer, B; Nielsen, EB; Schmidt, K; Southam, E | 1 |
| Beart, PM; Frandsen, A; Schousboe, A | 1 |
| Berisha, HI; Pakbaz, H; Said, SI | 2 |
| Bartley, DA; Dawson, TM; Dawson, VL; Snyder, SH; Uhl, GR | 1 |
| Ambrosini, A; Racagni, G | 1 |
| Ambrosini, A; Bresciani, L; Brunello, N; Fracchia, S; Racagni, G | 1 |
| Cui, LN; Inenaga, K; Nagatomo, T; Yamashita, H | 1 |
| Frandsen, A; Schousboe, A | 1 |
| Johnston, HM; Morris, BJ | 3 |
| Gonzales, JM; Irvine, S; Loeb, AL; Reichard, PS | 1 |
| Hsu, GL; Lue, TF; Martinez-Piñeiro, L; Tanagho, EA; Trigo-Rocha, F; von Heyden, B | 1 |
| Chang, CM; Chang, LW; Wei, JW | 1 |
| Matsuki, N; Saito, H; Tanaka, T | 1 |
| Madison, DV; Meffert, MK; Schulman, H; Schuman, EM | 1 |
| Amir, S | 1 |
| Bockaert, J; Lafon-Cazal, M; Marin, P; Quignard, JF | 1 |
| Choi, DW; Corbett, JA; Hewett, SJ; McDaniel, ML | 1 |
| Li, J; Smith, SS | 1 |
| Cler, JA; Cordi, AA; Dappen, MS; Emmett, MR; Gray, NM; Iyengar, S; Mick, SJ; Monahan, JB; Rao, TS; Wood, PL | 1 |
| Nicklas, WJ; Schoepp, D; Zeevalk, GD | 1 |
| Maura, G; Raiteri, M | 1 |
| Belsham, DD; Mellon, PL; Wetsel, WC | 1 |
| Kalra, PS; Kalra, SP; Pu, S; Xu, B | 1 |
| Chalimoniuk, M; Samochocki, M; Strosznajder, J | 1 |
| McCaslin, PP; Oh, S | 1 |
| Eboli, ML; Esposito, E; Riccio, A | 1 |
| de Vente, J; Rinkens, A; Steinbusch, HW; van Eden, CG | 1 |
| Beart, PM; Carroll, FY; Cheung, NS | 1 |
| Grieve, A; Griffiths, R; Malcolm, C; Ritchie, L; Schousboe, A | 1 |
| Basile, AS; Fossom, LH; Skolnick, P | 1 |
| Aguilar, E; González, D; Pinilla, L; Tena-Sempere, M | 1 |
| Fedele, E; Jin, Y; Raiteri, M; Varnier, G | 1 |
| De Vente, J; Johns, RA; Zuo, Z | 1 |
| Eblen, F; Klockgether, T; Löschmann, PA; Turski, L; Wüllner, U | 1 |
| Angeretti, N; Chiesa, R; Forloni, G; Lucca, E; Vezzani, A | 1 |
| Bisaglia, M; Fedele, E; Raiteri, M | 1 |
| Haberecht, MF; Lo, GJ; Mitchell, CK; Redburn, DA | 1 |
| Hu, PS; Ross, SB | 1 |
| Johns, RA; Pajewski, TN; Rengasamy, A | 1 |
| McCaslin, PP; Oh, S; Tokuyama, S | 1 |
| Baron, BM; Fadayel, GM; Harrison, BL; Kehne, JH; McCloskey, TC; Murawsky, MK; Nyce, P; Salituro, FG; Schmidt, CJ; Senyah, Y; Siegel, BW; Taylor, VL; van Giersbergen, PL; White, HS | 1 |
| Akunne, HC; Corbin, AE; Heffner, TG; Ninteman, FW; Pei, Y; Pugsley, TA; Tecle, H; Whetzel, SZ; Wiley, JN | 1 |
| Blanco, I; Bockaert, J; Lafon-Cazal, M; Rodriguez-Alvarez, J | 1 |
| Marcoli, M; Maura, G; Raiteri, M; Tortarolo, M | 2 |
| Agulló, L; Baltrons, MA; García, A; Saadoun, S | 1 |
| Fabiano, C; Ientile, R; Macaione, S; Macaione, V; Pedale, S; Picciurro, V | 1 |
| Kitamura, R; Miyawaki, I; Mori, K; Nakamura, K; Yokubol, B | 1 |
| Dai, D; Pantazis, NJ; West, JR | 1 |
| Gomi, H; Kimura, S; Kudoh, M; Shibuki, K; Takahashi, K; Takeda, M; Wakatsuki, H | 1 |
| Felipo, V; Gaztelu, JM; Hermenegildo, C; Llansola, M; Miñana, MD; Montoliu, C; Muñoz, MD | 1 |
| Cuénod, M; Do, KQ; Grima, G; Mayer, B; Pfeiffer, S | 1 |
| Akaike, A; Ibi, M; Inoue, R; Kihara, T; Kimura, J; Kitamura, Y; Sawada, H; Shimohama, S; Taniguchi, T; Urushitani, M | 1 |
| Ansaldo, MA; Fedele, E; Raiteri, M; Varnier, G | 2 |
| Blute, TA; De Grenier, J; Eldred, WD | 1 |
| Bockaert, J; Fagni, L; Guiraud, MJ; Lafon-Cazal, M; Lerner-Natoli, M; Mary, S; Pin, JP; Shigemoto, R | 1 |
| McCaslin, PP; Oh, S; Ryoo, IJ; Yoo, ID; Yun, BS | 1 |
| Cannavò, L; Ginoprelli, T; Ientile, R; Macaione, S; Pedale, S | 1 |
| Coffin, DO; Hewett, SJ; Kim, S; Vidwans, AS; Wink, DA | 1 |
| Felipo, V; Hermenegildo, C; Manzo, L; Minoia, C; Sáez, R | 1 |
| Charles, SL; Salt, TE; Shaw, PJ | 1 |
| Johns, RA; Tichotsky, A; Zuo, Z | 1 |
| Haddad, E; Hassan, A; Johns, RA; Tao, YX | 1 |
| Chalimoniuk, M; Stepień, A; Strosznajder, J | 1 |
| Belsham, DD; Mellon, PL | 1 |
| De Laurentiis, A; Faletti, AG; Lomniczi, A; Mastronardi, CA; McCann, SM; Rettori, V; Seilicovich, A | 1 |
| Johns, RA; Tao, YX | 1 |
| Bai, D; Jackson, MF; Jia, Z; Lei, S; MacDonald, JF; Orser, BA; Roder, J | 1 |
| Marcoli, M; Maura, G; Pepicelli, O; Raiteri, M; Rosu, C; Viola, C | 1 |
| Díaz-Trelles, R; Fernández-Sánchez, MT; Marini, A; Novelli, A; Vega, JA | 1 |
| Axer, H; Steinbusch, HW; Teunissen, CE | 1 |
| Delahunty, TM; Hamm, RJ; Lyeth, BG; Phillips, LL; Povlishock, JT; Temple, MD | 1 |
| Corbalán, R; Córdoba, J; Felipo, V; López-Talavera, J; Martinez, L; Monfort, P | 1 |
| Di Renzo, G; Lorenzon, T; Navarra, M; Romano, C; Rotiroti, D | 1 |
| Chai, CY; Su, CK; Wang, Y; Wu, WC | 1 |
| Barnstable, CJ; Cohen, ED; Daw, NW; Jin, X; Wei, JY | 1 |
| Lee, YJ; Tsai, LH | 1 |
| Butcher, SP; Macleod, MR | 1 |
| O'Donnell, JM; Suvarna, NU | 1 |
| Felipo, V; Llansola, M | 2 |
| Clark, JD; Li, X | 1 |
| Duffy, S; Horn, TF; Keilhoff, G; MacVicar, BA; Weiss, S; Wolf, G | 1 |
| Aarts, M; Arundine, M; Besshoh, S; Gurd, JW; Liu, L; Liu, Y; Salter, MW; Tymianski, M; Wang, YT | 1 |
| Dall'Olio, R; Gaggi, R; Gandolfi, O; Voltattorni, M | 1 |
| Bonavita, C; Cereseto, M; Ferrero, A; Rubio, M; Velardez, M; Wikinski, S | 1 |
| Albrecht, J; Anderzhanova, E; Hilgier, W; Oja, SS; Saransaari, P | 1 |
| Oja, SS; Saransaari, P | 1 |
| d'Ischia, M; Di Cosmo, A; Fiore, G; Palumbo, A; Poli, A | 1 |
| Duport, S; Garthwaite, J; Keynes, RG | 1 |
| Bucelli, RC; Rabin, RA; Regina, MJ; Winter, JC | 1 |
| Chai, CY; Su, CK; Wu, WC; Yang, CY | 1 |
| Katsura, M; Mohri, Y; Ohkuma, S; Shibata, D; Shuto, K; Tachi, M; Tsujimura, A | 1 |
| Cassano, T; Cuomo, V; Kendrick, KM; Steardo, L; Trabace, L; Tucci, P | 1 |
| Aizenman, E; Epstein, PM; Herin, GA; Li, Y; Lu, Y; Rosenberg, PA | 1 |
| Díaz-Trelles, R; Fernández-Sánchez, MT; Groppetti, A; Novelli, A | 1 |
| Funahashi, M; Hanazaki, M; Kohjitani, A; Matsuo, R; Miyawaki, T; Shimada, M | 1 |
| Kodama, T; Koyama, Y | 1 |
| Jurado, S; Lamas, S; Reimunde, FM; Rodríguez-Pascual, F; Sánchez-Prieto, J; Torres, M | 1 |
| Felipo, V; Llansola, M; Sánchez-Pérez, AM | 1 |
| Alexander, GM; Godwin, DW; Kurukulasuriya, NC; Mu, J | 1 |
| Garthwaite, J; Hopper, RA | 1 |
| Erceg, S; Felipo, V; Llansola, M; Monfort, P; Montoliu, C | 1 |
| Erceg, S; Felipo, V; Piedrafita, B; Rodrigo, R; Rodriguez-Diaz, J; Saez-Valero, J; Suarez, I | 1 |
| Cauli, O; Felipo, V; Montoliu, C; Piedrafita, B | 1 |
| Anrather, J; Iadecola, C; Kawano, T; Kunz, A; Orio, M; Zhou, P | 1 |
| Brocardo, Pde S; Budni, J; Kaster, MP; Lobato, KR; Rodrigues, AL | 1 |
| Goudarz, SH; Minoo, I; Shahpar, S; Vahid, N | 1 |
| Corlew, R; Currie, DA; de Vente, J; Moody, WJ | 1 |
| Anrather, J; Gallo, EF; Girouard, H; Iadecola, C; Pickel, VM; Wang, G; Zhou, P | 1 |
| Felipo, V; Llansola, M; Montoliu, C; Piedrafita, B; Rodrigo, R | 1 |
| Eysel, UT; Koesling, D; Mergia, E; Mittmann, T; Neitz, A; Taqatqeh, F | 1 |
| Johnson, SW; Shen, KZ | 1 |
| Boix, J; Cauli, O; Felipo, V | 1 |
| Agustí, A; Cauli, O; Felipo, V; González-Usano, A | 2 |
| Balen, Gde O; Budni, J; Fernandes, SC; Freitas, AE; Moretti, M; Rodrigues, AL | 1 |
| Albrecht, J; Frontczak-Baniewicz, M; Hilgier, W; Strużynska, L; Łazarewicz, JW | 1 |
| Bettio, LE; Budni, J; Colla, AR; Cunha, MP; Oliveira, Á; Pazini, FL; Rodrigues, AL | 1 |
| Aguiar, DC; Deolindo, MV; Guimarães, FS; Hott, SC; Resstel, LB | 1 |
| Batista, Ede J; Brasil, A; Crespo-Lopez, ME; Herculano, AM; Lima, MG; Matos Oliveira, KR; Maximino, C; Picanço-Diniz, DL; Rocha, FA | 1 |
| Ding, S; Hu, J; Huang, W; Lin, Y; Liu, L; Lu, Q; Wang, X; Yang, J; Ye, Y | 1 |
| Crystal, JD; Hohmann, AG; Kulkarni, PM; Lai, YY; Smith, AE; Thakur, GA; Xu, Z | 1 |
| Mantovani, AC; Nogueira, CW; Pesarico, AP; Rosa, SG; Stangherlin, EC; Zeni, G | 1 |
| Dehpour, AR; Imran Khan, M; Norouzi-Javidan, A; Ostadhadi, S | 1 |
| Balogh, C; Battonyai, I; Elekes, K; Hegedűs, C; Nacsa, K; Serfőző, Z; Veréb, Z | 1 |
| Chen, G; Ge, R; Guo, X; Nie, C; Qian, S; Shen, Q; Sheng, L; Sun, Y; Wang, W; Xue, W; Yao, Y; Zhang, H; Zhang, Y; Zhou, T | 1 |
| Aman, W; Dehpour, AR; Haider, A; Khan, MI; Khan, SN; Mumtaz, F; Naveed, A; Nikoui, V; Ullah, N; Wahab, A; Zaman, H | 1 |
| Giesen, J; Koesling, D; Mergia, E; Russwurm, M | 1 |
| Cabrera-Pastor, A; Felipo, V; Sancho-Alonso, M; Taoro-Gonzalez, L; Teruel-Martí, V | 1 |
| da Motta, KP; Luchese, C; Martins, CC; Reis, AS; Wilhelm, EA | 1 |
2 review(s) available for n-methylaspartate and cyclic gmp
| Article | Year |
|---|---|
Involvement of nitric oxide in ischemia-evoked taurine release in the mouse hippocampus.
Topics: Animals; Brain Ischemia; Cyclic GMP; Hippocampus; Mice; N-Methylaspartate; Nitric Oxide; Nitric Oxide Donors; Taurine | 2003 |
Nitric oxide as a regulatory molecule in the processing of the visual stimulus.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cyclic GMP; Gene Expression Regulation; Geniculate Bodies; Glutamine; Humans; N-Methylaspartate; Neurons; Nitric Oxide; Retina; Retinal Ganglion Cells; Signal Transduction; Vision, Ocular; Visual Cortex | 2014 |
203 other study(ies) available for n-methylaspartate and cyclic gmp
| Article | Year |
|---|---|
Nitric oxide-induced blockade of NMDA receptors.
Topics: Animals; Calcium; Cyclic GMP; In Vitro Techniques; Mice; Molsidomine; N-Methylaspartate; N-Nitrosopyrrolidine; Nitric Oxide; Nitroso Compounds; Receptors, N-Methyl-D-Aspartate; Sodium Nitrite | 1992 |
Sodium nitroprusside inhibits N-methyl-D-aspartate-evoked calcium influx via a nitric oxide- and cGMP-independent mechanism.
Topics: Animals; Biological Transport; Calcium; Cells, Cultured; Cyclic GMP; N-Methylaspartate; Neurons; Nitric Oxide; Nitroprusside; Rats; Rats, Inbred Strains | 1992 |
Nitric oxide does not mediate the neurotrophic effects of excitatory amino acids in cultured cerebellar granule neurons.
Topics: Animals; Arginine; Cell Survival; Cells, Cultured; Cerebellum; Cyclic GMP; Drug Stability; Kainic Acid; N-Methylaspartate; Nitric Oxide; Nitroarginine; Penicillamine; Rats; Rats, Inbred Strains; S-Nitroso-N-Acetylpenicillamine | 1992 |
Excitatory amino acid signal transduction in the hippocampus: role of noradrenergic afferents and nitric oxide in cGMP increases in vivo.
Topics: Analysis of Variance; Animals; Cyclic GMP; Hippocampus; Kainic Acid; Male; N-Methylaspartate; Nitric Oxide; Norepinephrine; Quisqualic Acid; Rats; Rats, Inbred Strains; Signal Transduction | 1992 |
Noncompetitive inhibition of N-methyl-D-aspartate by conantokin-G: evidence for an allosteric interaction at polyamine sites.
Topics: Animals; Binding Sites; Cerebellum; Conotoxins; Cyclic GMP; Dizocilpine Maleate; Granulocytes; Male; Mollusk Venoms; N-Methylaspartate; Osmolar Concentration; Peptides, Cyclic; Polyamines; Prosencephalon; Rats; Rats, Sprague-Dawley | 1992 |
Characterization of 3-carboxy-5-phosphono-1,2,3,4-tetrahydroisoquinoline (SC-48981), a potent competitive N-methy-D-aspartate (NMDA) receptor antagonist, in vitro and in vivo.
Topics: Animals; Binding, Competitive; Cerebellum; Cyclic GMP; Glutamates; Glutamic Acid; Glycine; In Vitro Techniques; Isoquinolines; Male; Mice; N-Methylaspartate; Organophosphorus Compounds; Phencyclidine; Receptors, N-Methyl-D-Aspartate; Tetrahydroisoquinolines | 1992 |
NMDA-, but not kainate- or quisqualate-dependent increases in cerebellar cGMP are dependent upon monoaminergic innervation.
Topics: Animals; Cerebellum; Cyclic GMP; Kainic Acid; Male; Mice; N-Methylaspartate; Neurotransmitter Agents; Norepinephrine; Quisqualic Acid; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Serine | 1992 |
Glutamate receptor agonists stimulate nitric oxide synthase in primary cultures of cerebellar granule cells.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Calcium; Cells, Cultured; Cerebellum; Citrulline; Cyclic GMP; Glutamates; Glutamic Acid; Granulocytes; Kainic Acid; N-Methylaspartate; Nitric Oxide Synthase; Quisqualic Acid; Receptors, Glutamate; Receptors, Neurotransmitter | 1992 |
Possible role of cGMP in excitatory amino acid induced cytotoxicity in cultured cerebral cortical neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Cell Death; Cells, Cultured; Cerebral Cortex; Cholera Toxin; Cyclic GMP; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; Ibotenic Acid; Kainic Acid; Mice; N-Methylaspartate; Neurons; Pertussis Toxin; Quisqualic Acid; Time Factors; Virulence Factors, Bordetella | 1992 |
In vitro interaction between cerebellar astrocytes and granule cells: a putative role for nitric oxide.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Astrocytes; Calcimycin; Cell Communication; Cells, Cultured; Cerebellum; Citrulline; Cyclic GMP; Kinetics; N-Methylaspartate; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; Rats | 1992 |
Nitric oxide may act as a messenger between dorsal root ganglion neurones and their satellite cells.
Topics: Amino Acid Oxidoreductases; Animals; Cyclic GMP; Ganglia, Spinal; N-Methylaspartate; NADP; NADPH Dehydrogenase; Neurotransmitter Agents; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; Rats | 1992 |
The ES-242s, novel N-methyl-D-aspartate antagonists of microbial origin, interact with both the neurotransmitter recognition site and the ion channel domain.
Topics: Animals; Binding, Competitive; Biological Transport; Calcium; Cells, Cultured; Cyclic GMP; Dizocilpine Maleate; Hippocampus; Ion Channels; Kinetics; Mice; N-Methylaspartate; Neurons; Neurotransmitter Agents; Phencyclidine; Pipecolic Acids; Pyrans; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Synaptic Membranes | 1992 |
NMDA receptor activation in rat hippocampus induces cyclic GMP formation through the L-arginine-nitric oxide pathway.
Topics: Animals; Arginine; Cyclic GMP; Hippocampus; In Vitro Techniques; Kinetics; N-Methylaspartate; Nitric Oxide; Nitroarginine; omega-N-Methylarginine; Rats; Receptors, N-Methyl-D-Aspartate | 1991 |
Nitric oxide mediates glutamate neurotoxicity in primary cortical cultures.
Topics: Animals; Arginine; Cell Survival; Cells, Cultured; Citrulline; Cyclic GMP; Dizocilpine Maleate; Fetus; Glutamates; Hemoglobins; Hippocampus; Kinetics; N-Methylaspartate; Neurons; Neurotoxins; Nitric Oxide; Rats; Receptors, N-Methyl-D-Aspartate; Superoxide Dismutase | 1991 |
1,10-bis(guanidino)decane inhibits N-methyl-D-aspartate responses in vitro and in vivo.
Topics: Animals; Calcium; Cells, Cultured; Cyclic GMP; Dizocilpine Maleate; Glycine; Guanidines; Male; Mice; Mice, Inbred Strains; N-Methylaspartate; Neurons; Prosencephalon; Rats; Receptors, N-Methyl-D-Aspartate; Tritium | 1991 |
The relative potency of pentobarbital in suppressing the kainic acid- or the N-methyl-D-aspartic acid-induced enhancement of cGMP in cerebellar cells.
Topics: Animals; Cells, Cultured; Cerebellum; Cyclic GMP; Kainic Acid; N-Methylaspartate; Neurons; Pentobarbital; Rats; Rats, Inbred Strains | 1991 |
Activation of presynaptic 5-hydroxytryptamine1-like receptors on glutamatergic terminals inhibits N-methyl-D-aspartate-induced cyclic GMP production in rat cerebellar slices.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Calcium; Cerebellum; Citalopram; Cyclic GMP; Fenfluramine; Glutamates; Glutamic Acid; In Vitro Techniques; Male; Methiothepin; N-Methylaspartate; Potassium; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, Cell Surface; Receptors, N-Methyl-D-Aspartate; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Tetrahydronaphthalenes | 1991 |
Intercellular action of nitric oxide in adult rat cerebellar slices.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cerebellum; Cyclic GMP; Drug Interactions; Glutamates; Glutamic Acid; Hemoglobins; Hydroxylamine; Hydroxylamines; Ibotenic Acid; Kainic Acid; Molsidomine; N-Methylaspartate; Nitric Oxide; Nitroprusside; Penicillamine; Rats; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; S-Nitroso-N-Acetylpenicillamine | 1991 |
Absence of implication of L-arginine/nitric oxide pathway on neuronal cell injury induced by L-glutamate or hypoxia.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Arginine; Brain; Cell Hypoxia; Cells, Cultured; Cyclic GMP; Dizocilpine Maleate; Fetus; Glutamates; Glutamic Acid; Kainic Acid; Kinetics; N-Methylaspartate; Neuroglia; Neurons; Nitric Oxide; Nitroarginine; Nitroprusside; omega-N-Methylarginine; Quisqualic Acid; Rats | 1991 |
Nitric oxide synthesis in the CNS endothelium and macrophages differs in its sensitivity to inhibition by arginine analogues.
Topics: Animals; Arginine; Central Nervous System; Cyclic GMP; Endothelium; In Vitro Techniques; Macrophages; Mice; N-Methylaspartate; Nitric Oxide; Nitroarginine; omega-N-Methylarginine; Rats | 1991 |
Contrasting neurochemical interactions of tiletamine, a potent phencyclidine (PCP) receptor ligand, with the N-methyl-D-aspartate-coupled and -uncoupled PCP recognition sites.
Topics: Animals; Behavior, Animal; Binding Sites; Cerebral Cortex; Cyclic GMP; Dizocilpine Maleate; Dopamine; Drug Interactions; Ligands; Male; N-Methylaspartate; Olfactory Pathways; Phencyclidine; Rats; Rats, Inbred Strains; Receptors, Neurotransmitter; Receptors, Phencyclidine; Tiletamine | 1991 |
Neurochemical interactions of competitive N-methyl-D-aspartate antagonists with dopaminergic neurotransmission and the cerebellar cyclic GMP system: functional evidence for a phasic glutamatergic control of the nigrostriatal dopaminergic pathway.
Topics: Animals; Cerebellum; Corpus Striatum; Cyclic GMP; Dopamine; Glutamine; Male; Mice; Mice, Inbred Strains; N-Methylaspartate; Rats; Rats, Inbred Strains; Substantia Nigra; Synaptic Transmission | 1991 |
Nanomolar N(G)-nitroarginine inhibits NMDA-induced cyclic GMP formation in rat cerebellum.
Topics: Animals; Arginine; Cerebellum; Cyclic GMP; In Vitro Techniques; N-Methylaspartate; Nitroarginine; Rats | 1990 |
(R)-4-oxo-5-phosphononorvaline: a new competitive glutamate antagonist at the NMDA receptor complex.
Topics: Animals; Binding, Competitive; Cerebellum; Cyclic GMP; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; Kindling, Neurologic; Mice; Mice, Inbred DBA; N-Methylaspartate; Rats; Receptors, N-Methyl-D-Aspartate; Valine | 1990 |
Excitatory amino acid receptor agonists stimulate membrane inositol phospholipid hydrolysis and increase cytoplasmic free Ca2+ in primary cultures of retinal neurons.
Topics: Amino Acids; Animals; Calcium; Cells, Cultured; Cyclic GMP; Cytoplasm; Glutamates; Glutamic Acid; Hydrolysis; Kainic Acid; N-Methylaspartate; Neurons; Phosphatidylinositols; Receptors, Amino Acid; Receptors, Cell Surface; Retina | 1990 |
In vivo antagonism of agonist actions at N-methyl-D-aspartate and N-methyl-D-aspartate-associated glycine receptors in mouse cerebellum: studies of 1-hydroxy-3-aminopyrrolidone-2.
Topics: Animals; Aspartic Acid; Cerebellum; Cyclic GMP; Male; Mice; N-Methylaspartate; Pyrrolidinones; Receptors, Glycine; Receptors, Neurotransmitter | 1990 |
Conantokin-G: a novel peptide antagonist to the N-methyl-D-aspartic acid (NMDA) receptor.
Topics: Amino Acid Sequence; Animals; Conotoxins; Cyclic GMP; Glutamates; Glycine; In Vitro Techniques; Kainic Acid; Molecular Sequence Data; N-Methylaspartate; Peptides, Cyclic; Phencyclidine; Rats; Receptors, N-Methyl-D-Aspartate; Tritium | 1990 |
Modulation of glutamate receptors by phencyclidine and glycine in the rat cerebellum: cGMP increase in vivo.
Topics: Amino Acids; Animals; Aspartic Acid; Binding, Competitive; Brain; Cerebellum; Cyclic GMP; Glycine; Injections, Intraventricular; N-Methylaspartate; Phencyclidine; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1989 |
N-methyl-D-aspartate receptors and ethanol: inhibition of calcium flux and cyclic GMP production.
Topics: Animals; Aspartic Acid; Calcium; Cells, Cultured; Cerebellum; Cyclic GMP; Dose-Response Relationship, Drug; Ethanol; Glycine; Granulocytes; N-Methylaspartate; Osmolar Concentration; Phencyclidine; Picrotoxin | 1989 |
Guanine nucleotides are competitive inhibitors of N-methyl-D-aspartate at its receptor site both in vitro and in vivo.
Topics: Animals; Aspartic Acid; Binding, Competitive; Brain; Calcium; Cerebellum; Cerebral Cortex; Cyclic GMP; Cytosol; Guanine Nucleotides; Hippocampus; Intracellular Membranes; Kinetics; Male; N-Methylaspartate; Neurons; Norepinephrine; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Synaptosomes | 1989 |
NMDA-coupled and uncoupled forms of the PCP receptor: preliminary in vivo evidence for PCP receptor subtypes.
Topics: Animals; Aspartic Acid; Cerebellum; Cyclic GMP; Harmaline; Ketamine; Male; N-Methylaspartate; Phencyclidine; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Receptors, Phencyclidine; Reference Values | 1989 |
In vivo modulation of the N-methyl-D-aspartate receptor complex by D-serine: potentiation of ongoing neuronal activity as evidenced by increased cerebellar cyclic GMP.
Topics: Animals; Aspartic Acid; Cerebellum; Cyclic GMP; Cycloserine; Dibenzocycloheptenes; Dizocilpine Maleate; Male; Mice; N-Methylaspartate; Neurons; Piperazines; Pyrrolidinones; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Serine | 1989 |
Increased response of cerebellar cGMP to kainate but not NMDA or quisqualate following barbital withdrawal from dependent rats.
Topics: Animals; Aspartic Acid; Barbital; Barbiturates; Cerebellum; Cyclic GMP; Dose-Response Relationship, Drug; Female; Injections, Intraventricular; Kainic Acid; N-Methylaspartate; Neuromuscular Depolarizing Agents; Oxadiazoles; Quisqualic Acid; Rats; Rats, Inbred Strains; Substance Withdrawal Syndrome; Substance-Related Disorders | 1989 |
Nitric oxide mediates glutamate-linked enhancement of cGMP levels in the cerebellum.
Topics: Animals; Arginine; Aspartic Acid; Cerebellum; Citrulline; Cyclic GMP; Glutamates; Glutamic Acid; Hemoglobins; In Vitro Techniques; Kainic Acid; Kinetics; N-Methylaspartate; Nitric Oxide; omega-N-Methylarginine; Oxadiazoles; Quisqualic Acid; Rats | 1989 |
2-Amino-7-phosphonoheptanoic acid, a selective antagonist of N-methyl-D-aspartate, prevents barbital withdrawal-induced convulsions and the elevation of cerebellar cyclic GMP in dependent rats.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Barbital; Barbiturates; Cerebellum; Cyclic GMP; Female; N-Methylaspartate; Rats; Rats, Inbred Strains; Seizures; Substance Withdrawal Syndrome; Substance-Related Disorders | 1987 |
Cultured cerebellar cells as an in vitro model of excitatory amino acid receptor function.
Topics: Animals; Aspartic Acid; Cells, Cultured; Cerebellum; Cyclic GMP; Kainic Acid; Models, Neurological; N-Methylaspartate; Neurons; Oxadiazoles; Quisqualic Acid; Radioimmunoassay; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, Cell Surface | 1987 |
Antagonism of N-methyl-D-aspartate (NMDA) evoked increases in cerebellar cGMP and striatal ACh release by phencyclidine (PCP) receptor agonists: evidence for possible allosteric coupling of NMDA and PCP receptors.
Topics: Acetylcholine; Animals; Aspartic Acid; Brain Chemistry; Cerebellum; Corpus Striatum; Cyclic GMP; Dose-Response Relationship, Drug; In Vitro Techniques; Male; Mice; N-Methylaspartate; Radioimmunoassay; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Receptors, Phencyclidine | 1987 |
Raised extracellular potassium relieves the blockade by magnesium of NMDA-induced cerebellar cyclic GMP production.
Topics: Animals; Aspartic Acid; Cerebellum; Cyclic GMP; Extracellular Space; Magnesium; Magnesium Sulfate; N-Methylaspartate; Osmolar Concentration; Potassium; Potassium Chloride; Rats | 1987 |
CGS 19755 is a potent and competitive antagonist at NMDA-type receptors.
Topics: Acetylcholine; Animals; Aspartic Acid; Binding, Competitive; Blood-Brain Barrier; Cerebellum; Cyclic GMP; Harmaline; Male; Mice; Mice, Inbred DBA; N-Methylaspartate; Pipecolic Acids; Piperidines; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Seizures | 1988 |
Ifenprodil and SL 82.0715 as cerebral anti-ischemic agents. II. Evidence for N-methyl-D-aspartate receptor antagonist properties.
Topics: Animals; Aspartic Acid; Brain Ischemia; Cells, Cultured; Cerebellum; Corpus Striatum; Cyclic GMP; Dopamine; Harmaline; In Vitro Techniques; Mice; N-Methylaspartate; Phencyclidine; Piperazines; Piperidines; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Spinal Cord | 1988 |
Sodium dependence of NMDA's effects on cyclic GMP production in immature rat cerebellar slices.
Topics: Animals; Aspartic Acid; Calcium Channels; Cerebellum; Cyclic GMP; N-Methylaspartate; Rats; Sodium | 1988 |
(+/-)-cis-2,3-Piperidine dicarboxylic acid is a partial N-methyl-D-aspartate agonist in the in vitro rat cerebellar cGMP model.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Aspartic Acid; Cerebellum; Cyclic GMP; Dose-Response Relationship, Drug; Female; In Vitro Techniques; Magnesium; Male; N-Methylaspartate; Pipecolic Acids; Rats; Rats, Inbred Strains; Valine | 1986 |
Continuously infused 2-amino-7-phosphonoheptanoic acid antagonizes N-methyl-D-aspartate-induced elevations of cyclic GMP in vivo in multiple brain areas and chemically-induced seizure activity.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Aspartic Acid; Barbiturates; Bicuculline; Brain; Brain Chemistry; Cyclic GMP; Female; Injections, Intraventricular; N-Methylaspartate; Pentylenetetrazole; Rats; Rats, Inbred Strains | 1986 |
Cellular origins of cyclic GMP responses to excitatory amino acid receptor agonists in rat cerebellum in vitro.
Topics: Amino Acids; Animals; Aspartic Acid; Cerebellum; Cyclic GMP; Drug Interactions; Glutamates; Glutamic Acid; In Vitro Techniques; Kainic Acid; N-Methylaspartate; Nitroprusside; Purkinje Cells; Rats; Tetrodotoxin | 1987 |
CPP, a selective N-methyl-D-aspartate (NMDA)-type receptor antagonist: characterization in vitro and in vivo.
Topics: Acetylcholine; Animals; Aspartic Acid; Cerebellum; Corpus Striatum; Cyclic GMP; Glutamates; Glutamic Acid; In Vitro Techniques; Kinetics; Male; Mice; Mice, Inbred DBA; N-Methylaspartate; Piperazines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Seizures | 1987 |
Novel kainic acid analogues. Effects on cyclic GMP content of adult rat cerebellar slices.
Topics: Animals; Aspartic Acid; Calcium; Cerebellum; Cyclic GMP; In Vitro Techniques; Kainic Acid; Male; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Rats; Receptors, Neurotransmitter; Structure-Activity Relationship | 1986 |
2-Amino-7-phosphonoheptanoic acid, a selective N-methyl-D-aspartate antagonist, blocks swim-induced elevation of cerebellar cyclic guanosine monophosphate.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Cerebellum; Cyclic GMP; Female; Motor Activity; N-Methylaspartate; Rats; Rats, Inbred Strains; Swimming | 1986 |
Ionic mechanisms implicated in the stimulation of cerebellar cyclic GMP levels by N-methyl-D-aspartate.
Topics: Animals; Aspartic Acid; Calcium; Cerebellum; Cyclic GMP; Dose-Response Relationship, Drug; Female; Male; N-Methylaspartate; Nifedipine; Rats; Zinc | 1987 |
Stimulation of rat cerebellar guanosine 3',5'-cyclic monophosphate (cyclic GMP) levels: effects of amino acid antagonists.
Topics: Amino Acids; Animals; Aspartic Acid; Calcium; Cerebellum; Cyclic GMP; Female; Glutamates; Glutamic Acid; In Vitro Techniques; Kainic Acid; Kinetics; N-Methylaspartate; Protoveratrines; Rats; Rats, Inbred Strains | 1981 |
Excitatory amino acid receptors and guanosine 3',5'-cyclic monophosphate in incubated slices of immature and adult rat cerebellum.
Topics: Amino Acids; Animals; Aspartic Acid; Cerebellum; Cyclic GMP; Glutamates; Glutamic Acid; In Vitro Techniques; Kainic Acid; N-Methylaspartate; Neurotransmitter Agents; Rats; Receptors, Amino Acid; Receptors, Cell Surface | 1982 |
Kainic acid stimulates excitatory amino acid neurotransmitter release at presynaptic receptors.
Topics: 2-Aminoadipic Acid; Animals; Aspartic Acid; Calcium; Cerebellum; Corpus Striatum; Cyclic GMP; Glutamates; Hippocampus; Kainic Acid; Male; Mice; N-Methylaspartate; Pyrrolidines; Receptors, Cell Surface; Receptors, Glutamate; Receptors, Neurotransmitter | 1982 |
Inhibition by N-acetyl-aspartate of aspartate binding to a proteolipid fraction from rat cerebral cortex.
Topics: Animals; Aspartic Acid; Cerebral Cortex; Cyclic AMP; Cyclic GMP; Male; N-Methylaspartate; Protein Binding; Proteolipids; Rats; Rats, Inbred Strains | 1984 |
Intrauterine hypoxia-ischemia increases N-methyl-D-aspartate-induced cGMP formation and glutamate accumulation in cultured rat cerebellar granule cells.
Topics: Animals; Arginine; Brain Ischemia; Cells, Cultured; Cerebellar Diseases; Chronic Disease; Cyclic GMP; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Fetal Hypoxia; Gestational Age; Glutamic Acid; Hypoxia, Brain; Kainic Acid; N-Methylaspartate; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley | 1995 |
NMDA-dependent prostaglandin E2 release by human cultured astroglial cells is driven by nitric oxide.
Topics: Arachidonic Acid; Arginine; Astrocytes; Astrocytoma; Cell Line; Cyclic GMP; Dinoprostone; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Kinetics; N-Methylaspartate; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Nitroprusside; Oxyhemoglobins; Receptors, N-Methyl-D-Aspartate; Tumor Cells, Cultured | 1995 |
Extracellular cGMP in the hippocampus of freely moving rats as an index of nitric oxide (NO) synthase activity.
Topics: Amino Acid Oxidoreductases; Animals; Behavior, Animal; Cyclic GMP; Extracellular Space; Hippocampus; Male; Microdialysis; Motor Activity; N-Methylaspartate; Nitric Oxide; Nitric Oxide Synthase; Phosphodiesterase Inhibitors; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 1994 |
Monitoring of cyclic GMP during cerebellar microdialysis in freely-moving rats as an index of nitric oxide synthase activity.
Topics: 1-Methyl-3-isobutylxanthine; Amino Acid Oxidoreductases; Animals; Cerebellum; Cyclic GMP; Extracellular Space; Male; Microdialysis; Monitoring, Physiologic; Motor Activity; N-Methylaspartate; Nitric Oxide Synthase; Phosphodiesterase Inhibitors; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 1993 |
Nitric oxide, superoxide and peroxynitrite: putative mediators of NMDA-induced cell death in cerebellar granule cells.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Catalase; Cell Death; Cells, Cultured; Cerebellum; Cyclic GMP; Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Mice; Molsidomine; N-Methylaspartate; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Receptors, N-Methyl-D-Aspartate; Superoxide Dismutase; Superoxides; Xanthine Oxidase | 1993 |
Lack of involvement of nitric oxide in NMDA-induced neuronal cell death in cortical culture.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cell Death; Cells, Cultured; Cerebral Cortex; Cyclic GMP; Models, Neurological; N-Methylaspartate; Neurons; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Rats | 1993 |
Involvement of granule, basket and stellate neurons but not Purkinje or Golgi cells in cerebellar cGMP increases in vivo.
Topics: Amino Acid Oxidoreductases; Amino Acids; Animals; Cerebellum; Cyclic GMP; Cytoplasmic Granules; Female; Golgi Apparatus; Harmaline; Immunohistochemistry; Methylazoxymethanol Acetate; Mice; Mice, Neurologic Mutants; N-Methylaspartate; Neurons; Nitric Oxide Synthase; Pregnancy; Purkinje Cells | 1994 |
Nitric oxide in retina: relation to excitatory amino acids and excitotoxicity.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cell Death; Chick Embryo; Cyclic GMP; gamma-Aminobutyric Acid; Glutamates; L-Lactate Dehydrogenase; N-Methylaspartate; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Retina | 1994 |
Glutamate receptors induce a burst of superoxide via activation of nitric oxide synthase in arginine-depleted neurons.
Topics: Amino Acid Oxidoreductases; Animals; Arginase; Arginine; Brain; Cell Death; Cells, Cultured; Cyclic GMP; Electron Spin Resonance Spectroscopy; Enzyme Activation; Male; Mice; N-Methylaspartate; Neurons; Nitric Oxide Synthase; Receptors, Glutamate; Superoxides | 1994 |
The NO-cGMP pathway in neonatal rat dorsal horn.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acid Oxidoreductases; Animals; Animals, Newborn; Arginine; Biomarkers; Cyclic GMP; Female; Glutathione; Male; N-Methylaspartate; NADPH Dehydrogenase; Nerve Tissue Proteins; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Nitroprusside; Nitroso Compounds; Pain; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; S-Nitrosoglutathione; Second Messenger Systems; Signal Transduction; Spinal Cord | 1994 |
Induction in the rat hippocampus of long-term potentiation (LTP) and long-term depression (LTD) in the presence of a nitric oxide synthase inhibitor.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cyclic GMP; Electric Stimulation; Evoked Potentials; Hippocampus; In Vitro Techniques; Long-Term Potentiation; N-Methylaspartate; Neuronal Plasticity; Neurons; Nitric Oxide Synthase; Nitroarginine; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Time Factors | 1994 |
Inhibitory effects of anesthetics on cyclic guanosine monophosphate (cGMP) accumulation in rat cerebellar slices.
Topics: 2-Amino-5-phosphonovalerate; Amino Acid Oxidoreductases; Anesthetics; Animals; Cerebellum; Cyclic GMP; Halothane; In Vitro Techniques; N-Methylaspartate; Nitric Oxide Synthase; Nitroprusside; Rats; Rats, Wistar; Thiopental | 1994 |
Blockade of nitric oxide synthesis by tyrosine kinase inhibitors in neurones.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Amino Acid Oxidoreductases; Animals; Calcium Channels; Cells, Cultured; Cerebellum; Cyclic GMP; Dizocilpine Maleate; Genistein; Isoflavones; Mice; N-Methylaspartate; Neostriatum; Neuronal Plasticity; Neurons; Nitric Oxide; Nitric Oxide Synthase; Patch-Clamp Techniques; Phenols; Protein-Tyrosine Kinases | 1994 |
Differential effects of nitric oxide gas and nitric oxide donors on depolarization-induced release of [3H]norepinephrine from rat hippocampal slices.
Topics: Amino Acid Oxidoreductases; Animals; Cells, Cultured; Cyclic GMP; Dopamine; Ferrocyanides; Hippocampus; In Vitro Techniques; Male; N-Methylaspartate; Neuromuscular Depolarizing Agents; Nitric Oxide; Nitric Oxide Synthase; Norepinephrine; Potassium Chloride; Rats; Rats, Sprague-Dawley | 1994 |
The role of nitric oxide in the transformation of visual information within the dorsal lateral geniculate nucleus of the cat.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cats; Cyclic GMP; Geniculate Bodies; Iontophoresis; N-Methylaspartate; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Receptors, N-Methyl-D-Aspartate; Vision, Ocular | 1994 |
The role of free radicals in NMDA-dependent neurotoxicity.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Calcium; Cells, Cultured; Cerebellar Cortex; Cyclic GMP; Electron Spin Resonance Spectroscopy; Enzyme Activation; Epilepsy; Feedback; Free Radicals; Glutamic Acid; Guanylate Cyclase; Kindling, Neurologic; Mice; Molsidomine; N-Methylaspartate; Nerve Tissue Proteins; Neurons; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Rats; Receptors, N-Methyl-D-Aspartate | 1994 |
Age-related changes in the NMDA receptor/nitric oxide/cGMP pathway in the hippocampus and cerebellum of freely moving rats subjected to transcerebral microdialysis.
Topics: Aging; Amino Acid Oxidoreductases; Animals; Behavior, Animal; Cerebellum; Cyclic GMP; Extracellular Space; Guanylate Cyclase; Hippocampus; Male; Microdialysis; N-Methylaspartate; Nitric Oxide; Nitric Oxide Synthase; Penicillamine; Phosphodiesterase Inhibitors; Rats; Rats, Inbred WKY; Receptors, N-Methyl-D-Aspartate; S-Nitroso-N-Acetylpenicillamine; Serine; Vasodilator Agents | 1995 |
Potent and selective inhibition of nitric oxide-sensitive guanylyl cyclase by 1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acid Oxidoreductases; Animals; Cattle; Cells, Cultured; Cerebellum; Cyclic GMP; Guanylate Cyclase; Hippocampus; In Vitro Techniques; N-Methylaspartate; Nitric Oxide; Nitric Oxide Synthase; Oxadiazoles; Quinoxalines; Rats; Rats, Wistar | 1995 |
Blockade by polyamine NMDA antagonists related to ifenprodil of NMDA-induced synthesis of cyclic GMP, increases in calcium and cytotoxicity in cultured neurones.
Topics: Animals; Calcium; Cells, Cultured; Cyclic GMP; Dose-Response Relationship, Drug; Female; Mice; N-Methylaspartate; Neurons; Piperidines; Propanolamines; Receptors, N-Methyl-D-Aspartate | 1995 |
N-methyl-D-aspartate receptors outside the central nervous system: activation causes acute lung injury that is mediated by nitric oxide synthesis and prevented by vasoactive intestinal peptide.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cyclic GMP; Lung Diseases; N-Methylaspartate; Nitric Oxide; Organ Size; Peripheral Nervous System; Rats; Receptors, N-Methyl-D-Aspartate; Vasoactive Intestinal Peptide | 1995 |
Mechanisms of nitric oxide-mediated neurotoxicity in primary brain cultures.
Topics: Amino Acid Oxidoreductases; Animals; Brain; Calcium; Cells, Cultured; Cyclic GMP; N-Methylaspartate; Neurons; Neurotoxins; Nitric Oxide; Nitric Oxide Synthase; Rats; Superoxides | 1993 |
Glutamate receptor-induced cyclic GMP formation in primary cultures of mesencephalic neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acid Oxidoreductases; Animals; Arginine; Carbachol; Cells, Cultured; Cyclic GMP; Fetus; Glutamates; Glutamic Acid; Ibotenic Acid; Kainic Acid; Kinetics; Mesencephalon; Mice; N-Methylaspartate; Neurons; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Phorbol 12,13-Dibutyrate; Quinoxalines; Receptors, Glutamate | 1993 |
Metabotropic glutamate receptors negatively coupled to adenylate cyclase inhibit N-methyl-D-aspartate receptor activity and prevent neurotoxicity in mesencephalic neurons in vitro.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Amino Acids, Dicarboxylic; Animals; Cells, Cultured; Cyclic GMP; Cycloleucine; GTP-Binding Proteins; In Vitro Techniques; Mesencephalon; Mice; N-Methylaspartate; Neurons; Neurotoxins; Phosphatidylinositols; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Second Messenger Systems | 1995 |
Sodium nitroprusside modulates NMDA response in the rat supraoptic neurons in vitro.
Topics: Animals; Arginine; Cyclic GMP; Ferricyanides; In Vitro Techniques; Isosorbide Dinitrate; Kainic Acid; Male; Membrane Potentials; N-Methylaspartate; Neurons; Nitroarginine; Nitroprusside; Protein Kinases; Quisqualic Acid; Rats; Rats, Wistar; Supraoptic Nucleus | 1994 |
Effect of magnesium on NMDA mediated toxicity and increases in [Ca2+]i and cGMP in cultured neocortical neurons: evidence for distinct regulation of different responses.
Topics: Animals; Calcium; Cells, Cultured; Cerebral Cortex; Culture Media; Cyclic GMP; Magnesium; Mice; N-Methylaspartate; Neurons | 1994 |
Selective regulation of dendritic MAP2 mRNA levels in hippocampal granule cells by nitric oxide.
Topics: Animals; Base Sequence; Cyclic GMP; Cytoskeleton; Dendrites; Gene Expression Regulation; Hippocampus; Male; Microtubule-Associated Proteins; Molecular Sequence Data; Molsidomine; N-Methylaspartate; Nerve Tissue Proteins; Nitric Oxide; Nitroprusside; Rats; Rats, Wistar; Receptors, Glutamate; RNA, Messenger | 1994 |
Ketamine inhibits glutamate-, N-methyl-D-aspartate-, and quisqualate-stimulated cGMP production in cultured cerebral neurons.
Topics: Animals; Brain; Cells, Cultured; Cyclic GMP; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glutamic Acid; Ketamine; N-Methylaspartate; Neurons; Nitric Oxide; Nitroprusside; Quisqualic Acid; Rats; Rats, Sprague-Dawley | 1995 |
Cyclic guanosine monophosphate mediates penile erection in the rat.
Topics: Alprostadil; Animals; Calcitonin Gene-Related Peptide; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Ethylmaleimide; Glutamates; Glutamic Acid; Male; Methylene Blue; Muscle Relaxation; N-Methylaspartate; Neurotransmitter Agents; Nitroprusside; Papaverine; Penile Erection; Rats; Rats, Sprague-Dawley; Vasoactive Intestinal Peptide | 1993 |
Differential responses in cyclic GMP formation induced by excitatory amino acids (EAA) and sodium nitroprusside (SNP) in various regions of the brain and of rats of varied age.
Topics: Aging; Amino Acids; Animals; Brain; Cyclic GMP; Female; Glutamates; Glutamic Acid; In Vitro Techniques; Kainic Acid; Male; N-Methylaspartate; Nitroprusside; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Sex Characteristics | 1993 |
Endogenous nitric oxide inhibits NMDA- and kainate- responses by a negative feedback system in rat hippocampal neurons.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Arginine; Calcium; Cells, Cultured; Cyclic GMP; Feedback; Glutamates; Glutamic Acid; Hemoglobins; Hippocampus; Kainic Acid; N-Methylaspartate; Neurons; Nitric Oxide; Nitroarginine; Osmolar Concentration; Rats; Rats, Wistar; Receptors, Amino Acid | 1993 |
Nitric oxide alters proenkephalin and prodynorphin gene expression in hippocampal granule cells.
Topics: 2-Amino-5-phosphonovalerate; Animals; Base Sequence; Cyclic GMP; Dendrites; Enkephalins; Gene Expression Regulation; Hippocampus; In Situ Hybridization; Molecular Sequence Data; Molsidomine; N-Methylaspartate; Nitric Oxide; Nitroprusside; Protein Precursors; Rats; RNA, Messenger; Vasodilator Agents | 1994 |
An ADP-ribosyltransferase as a potential target for nitric oxide action in hippocampal long-term potentiation.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cyclic GMP; Dibutyryl Cyclic GMP; Evoked Potentials; Hippocampus; In Vitro Techniques; Long-Term Potentiation; Male; Molsidomine; N-Methylaspartate; NAD; Niacinamide; Nitric Oxide; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Vasodilator Agents | 1994 |
N-Methyl-D-aspartate receptor-mediated signaling in the supraoptic nucleus involves activation of a nitric oxide-dependent pathway.
Topics: Animals; Arginine; Calcimycin; Chlorisondamine; Cyclic GMP; Heart Rate; Male; Microinjections; N-Methylaspartate; NG-Nitroarginine Methyl Ester; Nitric Oxide; Piperazines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Supraoptic Nucleus | 1994 |
Non-classical glutamate receptors, blocked by both NMDA and non-NMDA antagonists, stimulate nitric oxide production in neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Arginine; Cells, Cultured; Corpus Striatum; Cyclic GMP; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Female; Mice; N-Methylaspartate; Neurons; Nitric Oxide; Nitroarginine; omega-N-Methylarginine; Pregnancy; Quinoxalines; Quisqualic Acid; Receptors, Glutamate | 1993 |
NMDA and nitric oxide increase microtubule-associated protein 2 gene expression in hippocampal granule cells.
Topics: Animals; Base Sequence; Cyclic GMP; Gene Expression Regulation; Hippocampus; Male; Microinjections; Microtubule-Associated Proteins; Molecular Sequence Data; Molsidomine; N-Methylaspartate; Nitric Oxide; Rats; Rats, Wistar; RNA, Messenger | 1994 |
Inhibition of nitric oxide formation does not protect murine cortical cell cultures from N-methyl-D-aspartate neurotoxicity.
Topics: Animals; Arginine; Cell Death; Cells, Cultured; Cerebral Cortex; Cyclic GMP; Dextrorphan; Mice; N-Methylaspartate; Nitric Oxide; Nitroarginine; omega-N-Methylarginine; Rats | 1993 |
Novel action of nitric oxide as mediator of N-methyl-D-aspartate-induced phosphatidylinositol hydrolysis in neonatal rat cerebellum.
Topics: Animals; Animals, Newborn; Baclofen; Cerebellum; Cyclic GMP; Female; Hydrolysis; In Vitro Techniques; N-Methylaspartate; Nitric Oxide; Phosphatidylinositols; Rats | 1993 |
Indole-2-carboxylates, novel antagonists of the N-methyl-D-aspartate (NMDA)-associated glycine recognition sites: in vivo characterization.
Topics: Animals; Brain; Cerebellum; Cyclic GMP; Harmaline; Indoleacetic Acids; Kynurenic Acid; Ligands; Male; Mice; N-Methylaspartate; Pyrrolidinones; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1993 |
Aurintricarboxylic acid prevents NMDA-mediated excitotoxicity: evidence for its action as an NMDA receptor antagonist.
Topics: Animals; Aurintricarboxylic Acid; Chick Embryo; Cyclic GMP; GABA Antagonists; gamma-Aminobutyric Acid; N-Methylaspartate; Neurotoxins; Receptors, N-Methyl-D-Aspartate; Time Factors | 1993 |
Serotonin 5-HT1D and 5-HT1A receptors respectively mediate inhibition of glutamate release and inhibition of cyclic GMP production in rat cerebellum in vitro.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Afferent Pathways; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cerebellum; Cyclic GMP; Glutamic Acid; Male; N-Methylaspartate; Oxadiazoles; Piperazines; Potassium; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1D; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin; Serotonin Agents; Signal Transduction; Sumatriptan; Synapses; Synaptic Transmission | 1996 |
NMDA and nitric oxide act through the cGMP signal transduction pathway to repress hypothalamic gonadotropin-releasing hormone gene expression.
Topics: Animals; Base Sequence; Calcium; Cell Line; Cyclic GMP; DNA Primers; Excitatory Amino Acid Agonists; Gene Expression; Gonadotropin-Releasing Hormone; Guanylate Cyclase; Hypothalamus; Mice; Molecular Sequence Data; N-Methylaspartate; Nitric Oxide; Nitric Oxide Synthase; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Signal Transduction; Transfection | 1996 |
Evidence that gonadal steroids modulate nitric oxide efflux in the medial preoptic area: effects of N-methyl-D-aspartate and correlation with luteinizing hormone secretion.
Topics: 2-Amino-5-phosphonovalerate; Animals; Arginine; Cyclic GMP; Enzyme Inhibitors; Female; Luteinizing Hormone; Male; N-Methylaspartate; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Preoptic Area; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 1996 |
Excitotoxicity in the lung: N-methyl-D-aspartate-induced, nitric oxide-dependent, pulmonary edema is attenuated by vasoactive intestinal peptide and by inhibitors of poly(ADP-ribose) polymerase.
Topics: Animals; Arginine; Benzamides; Cyclic GMP; Enzyme Inhibitors; In Vitro Techniques; Lung; Lung Injury; Magnesium; Male; Models, Biological; N-Methylaspartate; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Perfusion; Poly(ADP-ribose) Polymerase Inhibitors; Pulmonary Edema; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Vasoactive Intestinal Peptide | 1996 |
Activation of serotonergic 5-HT1A receptor reduces Ca(2+)- and glutamatergic receptor-evoked arachidonic acid and No/cGMP release in adult hippocampus.
Topics: 2-Amino-5-phosphonovalerate; Animals; Arachidonic Acid; Buspirone; Calcium; Cyclic GMP; Enzyme Inhibitors; Hippocampus; In Vitro Techniques; Ketanserin; N-Methylaspartate; Neurons; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Quinacrine; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin; Synaptosomes | 1996 |
Kainate produces concentration-dependent elevation of glutamate release but not cGMP levels in cultured neuron.
Topics: Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Cerebellum; Cyclic GMP; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Kainic Acid; N-Methylaspartate; Neurons; Neurotoxins; Piperazines; Quinoxalines | 1996 |
Modulation by protein kinase C of nitric oxide and cyclic GMP poffation in cultured cerebellar granule cells.
Topics: Animals; Cells, Cultured; Cerebellum; Cyclic GMP; Down-Regulation; Enzyme Inhibitors; N-Methylaspartate; NADP; Naphthalenes; Nitric Oxide; Nitric Oxide Synthase; Protein Kinase C; Rats; Rats, Wistar; Staurosporine | 1996 |
Developmental pattern of NADPH-diaphorase activity and nitric oxide-stimulated cGMP immunoreactivity in the frontal rat cortex and its role in functional recovery from aspiration lesions.
Topics: Age Factors; Animals; Animals, Newborn; Cyclic GMP; Excitatory Amino Acid Agonists; Immunohistochemistry; N-Methylaspartate; NADPH Dehydrogenase; Nitric Oxide; Nitroprusside; Prefrontal Cortex; Rats; Rats, Wistar; Vasodilator Agents | 1996 |
NMDA-mediated activation of the NO/cGMP pathway: characteristics and regulation in cultured neocortical neurones.
Topics: Animals; Cells, Cultured; Cerebral Cortex; Cyclic GMP; Mice; N-Methylaspartate; Neurons; Nitric Oxide | 1996 |
NMDA receptor-mediated cGMP synthesis in primary cultures of mouse cerebellar granule cells appears to involve neuron-astrocyte communication with NO operating as the intercellular messenger.
Topics: Animals; Astrocytes; Calcimycin; Calcium; Calcium Channel Blockers; Cell Communication; Cells, Cultured; Cerebellum; Cyclic GMP; Excitatory Amino Acid Antagonists; Glutamate-Ammonia Ligase; Glutamic Acid; Hemoglobins; Kinetics; Magnesium; Mice; Mice, Inbred Strains; N-Methylaspartate; Neurons; Nifedipine; Nitric Oxide; Nitroarginine; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Verapamil | 1996 |
Sustained exposure to 1-aminocyclopropanecarboxylic acid, a glycine partial agonist, alters N-methyl-D-aspartate receptor function and subunit composition.
Topics: Amino Acids; Amino Acids, Cyclic; Animals; Calcium; Cell Death; Cerebellum; Cyclic GMP; Cytoplasmic Granules; Drug Synergism; Glutamic Acid; Glycine; Macromolecular Substances; Mice; N-Methylaspartate; Neurons; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; RNA; Stimulation, Chemical | 1995 |
Involvement of endogneous nitric oxide in the control of pituitary responsiveness to different elicitors of growth hormone release in prepubertal rats.
Topics: Animals; Cells, Cultured; Cyclic GMP; Enzyme Inhibitors; Female; Growth Hormone; Growth Hormone-Releasing Hormone; Male; N-Methylaspartate; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Nitroprusside; Oligopeptides; Pituitary Gland, Anterior; Rats; Rats, Wistar | 1996 |
In vivo microdialysis study of a specific inhibitor of soluble guanylyl cyclase on the glutamate receptor/nitric oxide/cyclic GMP pathway.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cerebellum; Cyclic GMP; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Guanylate Cyclase; Hippocampus; Male; Microdialysis; N-Methylaspartate; Nitric Oxide; Oxadiazoles; Penicillamine; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; S-Nitroso-N-Acetylpenicillamine | 1996 |
Halothane and isoflurane dose-dependently inhibit the cyclic GMP increase caused by N-methyl-D-aspartate in rat cerebellum: novel localization and quantitation by in vitro autoradiography.
Topics: Anesthetics, General; Animals; Autoradiography; Cerebellum; Cyclic GMP; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Halothane; Immunohistochemistry; In Vitro Techniques; Isoflurane; N-Methylaspartate; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley | 1996 |
Effects of 7-nitroindazole, NG-nitro-L-arginine, and D-CPPene on harmaline-induced postural tremor, N-methyl-D-aspartate-induced seizures, and lisuride-induced rotations in rats with nigral 6-hydroxydopamine lesions.
Topics: Animals; Anticonvulsants; Behavior, Animal; Brain; Cyclic GMP; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Harmaline; Hydroxydopamines; Indazoles; Lisuride; Locomotion; Male; N-Methylaspartate; Nitric Oxide Synthase; Nitroarginine; Piperazines; Rats; Receptors, N-Methyl-D-Aspartate; Seizures | 1996 |
Neuroprotective effect of somatostatin on nonapoptotic NMDA-induced neuronal death: role of cyclic GMP.
Topics: Animals; Cell Death; Cyclic GMP; Excitatory Amino Acid Agonists; N-Methylaspartate; Neurons; Neuroprotective Agents; Rats; Somatostatin | 1997 |
D-serine modulates the NMDA receptor/nitric oxide/cGMP pathway in the rat cerebellum during in vivo microdialysis.
Topics: Animals; Cerebellum; Cyclic GMP; Dose-Response Relationship, Drug; Male; Microdialysis; N-Methylaspartate; Nitric Oxide; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Serine | 1997 |
N-methyl-D-aspartate-mediated glutamate toxicity in the developing rabbit retina.
Topics: 2-Amino-5-phosphonovalerate; Aging; Animals; Animals, Newborn; Cell Death; Cyclic GMP; Dextromethorphan; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Glutamic Acid; N-Methylaspartate; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Rabbits; Receptors, N-Methyl-D-Aspartate; Retina | 1997 |
NMDA receptor-mediated increase in cyclic GMP in the rat cerebellum in vivo is blocked by alaproclate and GEA-857.
Topics: 4-Aminopyridine; Alanine; Animals; Behavior, Animal; Cerebellum; Convulsants; Cyclic GMP; Drug Interactions; Harmaline; Male; N-Methylaspartate; Pentylenetetrazole; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Seizures; Selective Serotonin Reuptake Inhibitors; Valine | 1997 |
Inhalational anesthetic effects on rat cerebellar nitric oxide and cyclic guanosine monophosphate production.
Topics: Anesthetics, Inhalation; Animals; Arginine; Cerebellum; Citrulline; Cyclic GMP; Drug Interactions; Excitatory Amino Acid Agonists; Halothane; Isoflurane; N-Methylaspartate; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Stimulation, Chemical; Tritium | 1997 |
Dual effects of NMDA-induced intracellular Ca2+ elevations on cGMP levels in cultured cerebellar granule neurons.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Calcium; Cells, Cultured; Cerebellum; Cyclic GMP; Excitatory Amino Acid Agonists; N-Methylaspartate; Neurons; Nitroprusside; Phosphodiesterase Inhibitors; Rats; Rats, Sprague-Dawley | 1997 |
Pharmacological characterization of MDL 105,519, an NMDA receptor glycine site antagonist.
Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Calcium Channels; Cells, Cultured; Cerebellum; Cyclic GMP; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Indoles; Ligands; Male; Mice; Mice, Inbred DBA; Motor Activity; N-Methylaspartate; Phencyclidine; Rats; Rats, Inbred F344; Rats, Wistar; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Sodium Channels | 1997 |
The pharmacology of the novel and selective sigma ligand, PD 144418.
Topics: Animals; Behavior, Animal; Brain; Calcium; Cells, Cultured; Cyclic GMP; Guinea Pigs; Haloperidol; Isoxazoles; Male; Mice; Motor Activity; N-Methylaspartate; Pyridines; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, sigma | 1997 |
Different routes of Ca2+ influx in NMDA-mediated generation of nitric oxide and arachidonic acid.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Arachidonic Acid; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-Type; Cells, Cultured; Cyclic GMP; Fetus; Kinetics; Mice; N-Methylaspartate; Neurons; Nifedipine; Nitric Oxide; omega-Agatoxin IVA; omega-Conotoxin GVIA; Peptides; Spider Venoms; Visual Cortex | 1997 |
Serotonin inhibition of the NMDA receptor/nitric oxide/cyclic GMP pathway in rat cerebellum: involvement of 5-hydroxytryptamine2C receptors.
Topics: Adrenergic alpha-Antagonists; Animals; Cerebellum; Cyclic GMP; Excitatory Amino Acid Agonists; Fluorobenzenes; Indoles; Male; N-Methylaspartate; Nitric Oxide; Organ Culture Techniques; Phenols; Piperidines; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2C; Receptors, N-Methyl-D-Aspartate; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Urea; Yohimbine | 1997 |
Regulation by calcium of the nitric oxide/cyclic GMP system in cerebellar granule cells and astroglia in culture.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Astrocytes; Calcium; Cells, Cultured; Cerebellum; Cyclic GMP; Enzyme Inhibitors; Guanylate Cyclase; Male; N-Methylaspartate; Nitric Oxide; Nitric Oxide Synthase; Phosphodiesterase Inhibitors; Rats; Rats, Sprague-Dawley; Sulfonamides; Vasodilator Agents | 1997 |
Actions of compounds manipulating the nitric oxide system in the cat primary visual cortex.
Topics: Acetylcholine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Arginine; Cats; Cyclic GMP; Electrophysiology; Enzyme Inhibitors; Excitatory Amino Acids; Hydrazines; Iontophoresis; N-Methylaspartate; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Nitrogen Oxides; Visual Cortex | 1997 |
Nitric oxide mediates NMDA-evoked [3H]GABA release from chick retina cells.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Cell Differentiation; Cells, Cultured; Chick Embryo; Cyclic GMP; Dizocilpine Maleate; gamma-Aminobutyric Acid; Isoquinolines; N-Methylaspartate; Nitric Oxide; Nitroarginine; Nitrogen Oxides; Purinones; Receptors, N-Methyl-D-Aspartate; Retina; Spermine; Tritium | 1997 |
Suppression of cyclic guanosine monophosphate formation in rat cerebellar slices by propofol, ketamine and midazolam.
Topics: Anesthetics, Intravenous; Animals; Cerebellum; Cyclic GMP; Depression, Chemical; Glutamic Acid; In Vitro Techniques; Ketamine; Midazolam; N-Methylaspartate; Nitroprusside; Propofol; Rats; Rats, Wistar; Vasodilator Agents | 1997 |
The nitric oxide-cyclic GMP pathway plays an essential role in both promoting cell survival of cerebellar granule cells in culture and protecting the cells against ethanol neurotoxicity.
Topics: Aminoquinolines; Animals; Cell Survival; Cells, Cultured; Cerebellum; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Ethanol; N-Methylaspartate; Neurons; Neuroprotective Agents; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroso Compounds; Rats; Rats, Sprague-Dawley | 1998 |
Trazodone is a potent agonist at 5-HT2C receptors mediating inhibition of the N-methyl-D-aspartate/nitric oxide/cyclic GMP pathway in rat cerebellum.
Topics: Animals; Anti-Anxiety Agents; Cerebellum; Cyclic GMP; Dose-Response Relationship, Drug; Male; N-Methylaspartate; Nitric Oxide; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Trazodone | 1998 |
Layer-specific NO dependence of long-term potentiation and biased NO release in layer V in the rat auditory cortex.
Topics: Animals; Auditory Cortex; Cyclic GMP; Electric Stimulation; Excitatory Amino Acid Agonists; Female; Immunohistochemistry; In Vitro Techniques; Long-Term Potentiation; Male; Membrane Potentials; N-Methylaspartate; Nerve Tissue Proteins; Neurons; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Rats; Rats, Wistar; Signal Transduction | 1998 |
Chronic hyperammonemia impairs the glutamate-nitric oxide-cyclic GMP pathway in cerebellar neurons in culture and in the rat in vivo.
Topics: Ammonia; Animals; Cell Death; Cells, Cultured; Cerebellum; Cyclic GMP; Dialysis Solutions; Dose-Response Relationship, Drug; Extracellular Space; Glutamic Acid; Male; Microdialysis; N-Methylaspartate; Neurons; Nitric Oxide; Perfusion; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Time Factors | 1998 |
Arginine availability controls the N-methyl-D-aspartate-induced nitric oxide synthesis: involvement of a glial-neuronal arginine transfer.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Arginine; Cerebellum; Cerebral Cortex; Cyclic GMP; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; In Vitro Techniques; N-Methylaspartate; Neuroglia; Neurons; Nitric Oxide; Nitroarginine; Rats; Rats, Inbred Strains | 1998 |
Mechanism of selective motor neuronal death after exposure of spinal cord to glutamate: involvement of glutamate-induced nitric oxide in motor neuron toxicity and nonmotor neuron protection.
Topics: Amyotrophic Lateral Sclerosis; Animals; Cell Death; Cell Survival; Cells, Cultured; Cyclic GMP; Dicarboxylic Acids; Embryo, Mammalian; Glutamic Acid; Models, Neurological; Motor Neurons; N-Methylaspartate; Neurons; Neurotransmitter Uptake Inhibitors; Nitric Oxide; Nitric Oxide Donors; Pyrrolidines; Rats; Rats, Wistar; Spinal Cord | 1998 |
Nicotine administration stimulates the in vivo N-methyl-D-aspartate receptor/nitric oxide/cyclic GMP pathway in rat hippocampus through glutamate release.
Topics: Amino Acids; Animals; Cyclic GMP; Ganglionic Stimulants; Glutamic Acid; Guanylate Cyclase; Hippocampus; Injections, Intraperitoneal; Male; N-Methylaspartate; Nicotine; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 1998 |
Stimulation with N-methyl-D-aspartate or kainic acid increases cyclic guanosine monophosphate-like immunoreactivity in turtle retina: involvement of nitric oxide synthase.
Topics: Animals; Cyclic GMP; Immunohistochemistry; Kainic Acid; N-Methylaspartate; Nitric Oxide Synthase; Receptors, Glutamate; Retina; Signal Transduction; Turtles | 1999 |
mGluR7-like metabotropic glutamate receptors inhibit NMDA-mediated excitotoxicity in cultured mouse cerebellar granule neurons.
Topics: Animals; Calcium Channels; Cell Death; Cells, Cultured; Cerebellum; Cyclic GMP; Cycloleucine; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Kainic Acid; Mice; Microtubule-Associated Proteins; N-Methylaspartate; Neurons; Neuroprotective Agents; Neurotoxins; Patch-Clamp Techniques; Phosphoserine; Propionates; Receptors, AMPA; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate | 1999 |
Nitric oxide synthase inhibitor decreases NMDA-induced elevations of extracellular glutamate and intracellular Ca2+ levels via a cGMP-independent mechanism in cerebellar granule neurons.
Topics: Animals; Calcium; Cells, Cultured; Cerebellum; Cyclic GMP; Dibutyryl Cyclic GMP; Excitatory Amino Acid Agonists; Extracellular Space; Glutamic Acid; N-Methylaspartate; Neurons; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley | 1999 |
Intracellular polyamine levels are involved in NMDA-evoked nitric oxide production in chick retina cells.
Topics: Animals; Arginine; Cells, Cultured; Chick Embryo; Citrulline; Cyclic GMP; Eflornithine; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Glycine; N-Methylaspartate; NADPH Dehydrogenase; Nitric Oxide; Nitric Oxide Synthase; Polyamines; Receptors, N-Methyl-D-Aspartate; Retina; Spermidine | 1999 |
Analysis of the neuroprotective effects of various nitric oxide donor compounds in murine mixed cortical cell culture.
Topics: Animals; Antioxidants; Calcium; Cells, Cultured; Cerebral Cortex; Cyclic GMP; Excitatory Amino Acid Agonists; Hydrazines; Intracellular Membranes; Mice; N-Methylaspartate; Neurons; Neuroprotective Agents; Neurotoxins; Nitric Oxide; Nitric Oxide Donors; Nitrogen Oxides; Rats; Rats, Inbred Strains | 1999 |
Chronic exposure to aluminium impairs the glutamate-nitric oxide-cyclic GMP pathway in the rat in vivo.
Topics: Aluminum; Animals; Calmodulin; Cyclic GMP; Enzyme Activation; Glutamic Acid; Guanylate Cyclase; Male; N-Methylaspartate; Nitric Oxide; Nitric Oxide Donors; Penicillamine; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; S-Nitroso-N-Acetylpenicillamine; Tissue Distribution | 1999 |
Actions of 8-bromo-cyclic-GMP on neurones in the rat thalamus in vivo and in vitro.
Topics: Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cyclic GMP; Evoked Potentials, Visual; Excitatory Amino Acid Agonists; Geniculate Bodies; Guanylate Cyclase; In Vitro Techniques; Molsidomine; N-Methylaspartate; Neurons, Afferent; Nitric Oxide; Nitric Oxide Donors; Rats; Rats, Wistar | 1999 |
Inhibition of excitatory neurotransmitter-nitric oxide signaling pathway by inhalational anesthetics.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Anesthetics, Inhalation; Animals; Arginine; Cells, Cultured; Cerebral Cortex; Cyclic GMP; Drug Interactions; Enzyme Activation; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Guanylate Cyclase; Halothane; Isoflurane; Kainic Acid; N-Methylaspartate; Neurons; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitroprusside; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Signal Transduction | 1999 |
Expression and action of cyclic GMP-dependent protein kinase Ialpha in inflammatory hyperalgesia in rat spinal cord.
Topics: Animals; Antibodies; Behavior, Animal; Cyclic GMP; Cyclic GMP-Dependent Protein Kinase Type I; Cyclic GMP-Dependent Protein Kinases; Dizocilpine Maleate; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Formaldehyde; Guanylate Cyclase; Hyperalgesia; Male; Myelitis; N-Methylaspartate; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nociceptors; Pain; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Spinal Cord; Thionucleotides | 2000 |
Serotonin 5HT1B/1D receptor agonists abolish NMDA receptor-evoked enhancement of nitric oxide synthase activity and cGMP concentration in brain cortex slices.
Topics: Animals; Cerebral Cortex; Cyclic GMP; Excitatory Amino Acid Agonists; Male; N-Methylaspartate; Nitric Oxide Synthase; Oxazoles; Oxazolidinones; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1B; Receptor, Serotonin, 5-HT1D; Receptors, N-Methyl-D-Aspartate; Receptors, Serotonin; Serotonin Receptor Agonists; Sumatriptan; Tryptamines | 1999 |
Transcription factors Oct-1 and C/EBPbeta (CCAAT/enhancer-binding protein-beta) are involved in the glutamate/nitric oxide/cyclic-guanosine 5'-monophosphate-mediated repression of mediated repression of gonadotropin-releasing hormone gene expression.
Topics: Animals; Binding Sites; CCAAT-Enhancer-Binding Proteins; Cell Line; Cyclic GMP; DNA-Binding Proteins; Enhancer Elements, Genetic; Gene Expression Regulation; Glutamic Acid; Gonadotropin-Releasing Hormone; Host Cell Factor C1; Hypothalamus; Mice; N-Methylaspartate; Neurons; Nitric Oxide; Nitroprusside; Nuclear Proteins; Octamer Transcription Factor-1; Rats; Repressor Proteins; Signal Transduction; Transcription Factors | 2000 |
Inhibitory pathways and the inhibition of luteinizing hormone-releasing hormone release by alcohol.
Topics: Animals; Arachidonic Acid; beta-Endorphin; Cyclic GMP; Dinoprostone; Ethanol; Excitatory Amino Acid Agonists; gamma-Aminobutyric Acid; Gonadotropin-Releasing Hormone; Hypothalamus; In Vitro Techniques; Male; N-Methylaspartate; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitroprusside; Rats; Rats, Wistar | 2000 |
Activation of cGMP-dependent protein kinase Ialpha is required for N-methyl-D-aspartate- or nitric oxide-produced spinal thermal hyperalgesia.
Topics: Animals; Cyclic GMP; Cyclic GMP-Dependent Protein Kinase Type I; Cyclic GMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Hyperalgesia; Injections, Spinal; Male; N-Methylaspartate; Nitric Oxide; Nitric Oxide Donors; Nitroso Compounds; Pain; Pain Measurement; Rats; Rats, Sprague-Dawley; Thionucleotides | 2000 |
Cyclic GMP-dependent feedback inhibition of AMPA receptors is independent of PKG.
Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinase Type 1; Calcium-Calmodulin-Dependent Protein Kinases; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Dibutyryl Cyclic GMP; Dose-Response Relationship, Drug; Excitatory Postsynaptic Potentials; Feedback; Glutamic Acid; Hippocampus; In Vitro Techniques; N-Methylaspartate; Neural Inhibition; Nitric Oxide Donors; Nitric Oxide Synthase; Patch-Clamp Techniques; Protein Kinase C; Protein Kinase Inhibitors; Protein Kinases; Pyramidal Cells; Rats; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission | 2000 |
Benzodiazepine-sensitive GABA(A) receptors limit the activity of the NMDA/NO/cyclic GMP pathway: a microdialysis study in the cerebellum of freely moving rats.
Topics: Animals; Anti-Anxiety Agents; Bicuculline; Cerebellum; Cyclic GMP; Diazepam; Flumazenil; Infusions, Parenteral; Kinetics; Male; Microdialysis; Muscimol; N-Methylaspartate; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Zolpidem | 2000 |
Serotonin inhibition of the NMDA receptor/nitric oxide/cyclic GMP pathway in human neocortex slices: involvement of 5-HT(2C) and 5-HT(1A) receptors.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adult; Aged; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Ethylamines; Female; Humans; In Vitro Techniques; Indoles; Male; Middle Aged; N-Methylaspartate; Neocortex; Nitric Oxide; Nitroarginine; Oxadiazoles; Piperazines; Pyridines; Quinoxalines; Receptor, Serotonin, 5-HT2C; Receptors, N-Methyl-D-Aspartate; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Signal Transduction; Trazodone | 2000 |
Antihistamine terfenadine potentiates NMDA receptor-mediated calcium influx, oxygen radical formation, and neuronal death.
Topics: Animals; Biological Transport; Calcium; Cell Death; Cell Survival; Cells, Cultured; Cerebellum; Chlorpheniramine; Cyclic GMP; Dizocilpine Maleate; Drug Synergism; Glutamic Acid; Histamine; Histamine H1 Antagonists; N-Methylaspartate; Neurons; Piperazines; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Terfenadine; Triprolidine | 2000 |
Whole brain spheroid cultures as a model to study the development of nitric oxide synthase-guanylate cyclase signal transduction.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Astrocytes; Atrial Natriuretic Factor; Brain; Cell Culture Techniques; Cells, Cultured; Cyclic GMP; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Female; Guanylate Cyclase; N-Methylaspartate; Neurons; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitroprusside; Oxadiazoles; Phosphodiesterase Inhibitors; Pregnancy; Quinoxalines; Rats; Rats, Inbred Lew; Signal Transduction; Vasodilator Agents | 2000 |
Subtle alterations in NMDA-stimulated cyclic GMP levels following lateral fluid percussion brain injury.
Topics: Animals; Brain Injuries; Cognition Disorders; Cyclic GMP; Disease Models, Animal; Functional Laterality; Hippocampus; Male; N-Methylaspartate; Percussion; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Time Factors | 2001 |
Altered content and modulation of soluble guanylate cyclase in the cerebellum of rats with portacaval anastomosis.
Topics: Animals; Cerebellum; Cyclic GMP; Disease Models, Animal; Enzyme Activators; Excitatory Amino Acid Agonists; Glutamic Acid; Guanylate Cyclase; Hepatic Encephalopathy; Hyperammonemia; Immunoblotting; Indazoles; Lymphocytes; Male; Microdialysis; N-Methylaspartate; Nitric Oxide; Nitric Oxide Donors; Penicillamine; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; S-Nitroso-N-Acetylpenicillamine; Synaptic Transmission | 2001 |
Ethanol exposure inhibits the cytotoxic effect induced by gp120 in CHP100 human neuroblastoma cells.
Topics: Calcium; Cell Death; Central Nervous System Depressants; Cyclic GMP; Dose-Response Relationship, Drug; Ethanol; Excitatory Amino Acid Agonists; HIV Envelope Protein gp120; Humans; N-Methylaspartate; Neuroblastoma; Neurons; Nitric Oxide; Tumor Cells, Cultured | 2001 |
The nNOS/cGMP signal transducing system is involved in the cardiovascular responses induced by activation of NMDA receptors in the rostral ventrolateral medulla of cats.
Topics: Animals; Blood Pressure; Bradycardia; Cats; Cyclic GMP; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Female; Guanylate Cyclase; Heart Rate; Hypertension; Indazoles; Male; Medulla Oblongata; N-Methylaspartate; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Oxadiazoles; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Signal Transduction | 2001 |
cGMP-induced presynaptic depression and postsynaptic facilitation at glutamatergic synapses in visual cortex.
Topics: Animals; Calcium; Calcium Channels; Cells, Cultured; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; Glutamic Acid; N-Methylaspartate; Neural Inhibition; Neurons; Oligopeptides; Patch-Clamp Techniques; Presynaptic Terminals; Rats; Visual Cortex | 2002 |
NMDA inhibits oxotremorine-induced acid secretion via the NO-dependent cyclic GMP system in rat stomach.
Topics: Animals; Cyclic GMP; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Gastric Acid; Gastric Mucosa; In Vitro Techniques; Male; N-Methylaspartate; Nitric Oxide; Nitroarginine; Oxotremorine; Rats; Rats, Sprague-Dawley | 2001 |
Nitric-oxide-synthase-mediated cyclic guanosine monophosphate production in neonatal rat cerebellar prisms is resistant to calcineurin inhibition.
Topics: Animals; Animals, Newborn; Brain Ischemia; Calcineurin; Calcineurin Inhibitors; Cerebellum; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Female; Immunosuppressive Agents; Male; N-Methylaspartate; Neurons; Neuroprotective Agents; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Phosphorylation; Phosphoserine; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Tacrolimus | 2002 |
Hydrolysis of N-methyl-D-aspartate receptor-stimulated cAMP and cGMP by PDE4 and PDE2 phosphodiesterases in primary neuronal cultures of rat cerebral cortex and hippocampus.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenine; Adenosine; Animals; Cells, Cultured; Cerebral Cortex; Cyclic AMP; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 2; Cyclic Nucleotide Phosphodiesterases, Type 4; Dizocilpine Maleate; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Guanylate Cyclase; Hippocampus; N-Methylaspartate; Neurons; Nitric Oxide Donors; Nitric Oxide Synthase; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Pregnancy; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Rolipram | 2002 |
Carnitine prevents NMDA receptor-mediated activation of MAP-kinase and phosphorylation of microtubule-associated protein 2 in cerebellar neurons in culture.
Topics: Animals; Carnitine; Cells, Cultured; Cerebellum; Cyclic GMP; Microtubule-Associated Proteins; Mitogen-Activated Protein Kinases; N-Methylaspartate; Neurons; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Phosphorylation; Precipitin Tests; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; S-Nitroso-N-Acetylpenicillamine | 2002 |
Spinal cord heme oxygenase participates in glutamate-induced pain-related behaviors.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Behavior, Animal; Cyclic GMP; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Glutamic Acid; Heme Oxygenase (Decyclizing); In Vitro Techniques; Injections, Spinal; Male; Mesoporphyrins; Metalloporphyrins; Mice; Mice, Inbred C57BL; Mice, Knockout; N-Methylaspartate; Pain; Protoporphyrins; Spinal Cord | 2002 |
Nitric oxide promotes intracellular calcium release from mitochondria in striatal neurons.
Topics: Animals; Calcium; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Cells, Cultured; Corpus Striatum; Cyclic GMP; Cyclosporine; Dose-Response Relationship, Drug; Glucose; Mice; Microscopy, Confocal; Mitochondria; N-Methylaspartate; Neurons; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Thapsigargin | 2002 |
Treatment of ischemic brain damage by perturbing NMDA receptor- PSD-95 protein interactions.
Topics: Amino Acid Sequence; Animals; Brain; Brain Ischemia; Calcium; Cells, Cultured; Cerebral Infarction; Cyclic GMP; Disks Large Homolog 4 Protein; Guanylate Kinases; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; Male; Membrane Proteins; Mice; Mice, Inbred C57BL; N-Methylaspartate; Nerve Tissue Proteins; Neurons; Patch-Clamp Techniques; Peptides; Protein Binding; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Recombinant Fusion Proteins; Signal Transduction; Synaptic Transmission | 2002 |
The activation of serotonin receptors prevents glutamate-induced neurotoxicity and NMDA-stimulated cGMP accumulation in primary cortical cell cultures.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Cell Survival; Cells, Cultured; Cyclic GMP; Glutamic Acid; Indophenol; N-Methylaspartate; Neocortex; Neurons; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin Receptor Agonists | 2002 |
Adaptive changes in the rat hippocampal glutamatergic neurotransmission are observed during long-term treatment with lorazepam.
Topics: Adaptation, Physiological; Animals; Anti-Anxiety Agents; Cyclic GMP; Dizocilpine Maleate; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Lorazepam; Male; N-Methylaspartate; Potassium; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission | 2003 |
Taurine reduces ammonia- and N-methyl-D-aspartate-induced accumulation of cyclic GMP and hydroxyl radicals in microdialysates of the rat striatum.
Topics: Ammonium Chloride; Animals; Chromatography, High Pressure Liquid; Corpus Striatum; Cyclic GMP; Hydroxyl Radical; Male; Microdialysis; N-Methylaspartate; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Taurine | 2003 |
Dopamine in the ink defence system of Sepia officinalis: biosynthesis, vesicular compartmentation in mature ink gland cells, nitric oxide (NO)/cGMP-induced depletion and fate in secreted ink.
Topics: Animals; Catecholamines; Cell Compartmentation; Cyclic GMP; Cytoplasmic Vesicles; Dihydroxyphenylalanine; Dopamine; Immunohistochemistry; Mollusca; N-Methylaspartate; Nitric Oxide | 2004 |
Hippocampal neurons in organotypic slice culture are highly resistant to damage by endogenous and exogenous nitric oxide.
Topics: Animals; Cell Death; Cyclic GMP; Dose-Response Relationship, Drug; Hippocampus; N-Methylaspartate; Neurons; Nitric Oxide; Organ Culture Techniques; Rats; Rats, Sprague-Dawley | 2004 |
Cellular mechanisms of serotonin 5-HT2A receptor-mediated cGMP formation: the essential role of glutamate.
Topics: Animals; Brain; Cyclic GMP; Glutamic Acid; Male; N-Methylaspartate; PC12 Cells; Rats; Rats, Inbred F344; Receptor, Serotonin, 5-HT2A; Receptors, N-Methyl-D-Aspartate; Serotonin 5-HT2 Receptor Agonists; Serotonin Receptor Agonists | 2004 |
The nNos/cGMP mediation of the depressor response to NMDA receptor stimulation in the caudal ventrolateral medulla.
Topics: Anesthesia; Animals; Blood Pressure; Cats; Cyclic GMP; Excitatory Amino Acid Agonists; Female; Heart Rate; Male; Medulla Oblongata; N-Methylaspartate; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Receptors, N-Methyl-D-Aspartate | 2003 |
Continuous exposure to nitric oxide enhances diazepam binding inhibitor mRNA expression in mouse cerebral cortical neurons.
Topics: Analysis of Variance; Animals; Blotting, Northern; Cells, Cultured; Cerebellar Cortex; Cyclic GMP; Diazepam Binding Inhibitor; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Gene Expression Regulation; Hybridization, Genetic; Immunohistochemistry; L-Lactate Dehydrogenase; Mice; N-Methylaspartate; Neurons; Nitric Oxide; Nitric Oxide Donors; Nitroso Compounds; Oxadiazoles; Phosphopyruvate Hydratase; RNA, Messenger; Time; Time Factors | 2004 |
The effects of nitric oxide on striatal serotoninergic transmission involve multiple targets: an in vivo microdialysis study in the awake rat.
Topics: Animals; Cyclic GMP; Enzyme Inhibitors; Free Radical Scavengers; Guanylate Cyclase; Male; Microdialysis; N-Methylaspartate; Neostriatum; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Peroxynitrous Acid; Rats; Rats, Wistar; Serotonin; Signal Transduction; Superoxides; Synaptic Transmission | 2004 |
Elevation of intracellular cAMP evokes activity-dependent release of adenosine in cultured rat forebrain neurons.
Topics: Adenosine; Animals; Animals, Newborn; Astrocytes; Cells, Cultured; Cyclic AMP; Cyclic GMP; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Interactions; Embryo, Mammalian; Enzyme Activation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Extracellular Space; Female; Glutamic Acid; Intracellular Space; Male; Membrane Potentials; Models, Neurological; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Phosphodiesterase Inhibitors; Pregnancy; Prosencephalon; Purinones; Rats; Rats, Sprague-Dawley; Thionucleotides | 2004 |
Nefopam inhibits calcium influx, cGMP formation, and NMDA receptor-dependent neurotoxicity following activation of voltage sensitive calcium channels.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Analgesics, Non-Narcotic; Animals; Calcium; Calcium Channel Agonists; Calcium Channels; Calcium Signaling; Cells, Cultured; Cyclic GMP; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Kainic Acid; N-Methylaspartate; Nefopam; Neuromuscular Depolarizing Agents; Neurons; Neurotoxins; Rats; Receptors, N-Methyl-D-Aspartate | 2005 |
Peripheral N-methyl-D-aspartate receptors modulate nonadrenergic noncholinergic lower esophageal sphincter relaxation in rabbits.
Topics: Animals; Cyclic GMP; Dizocilpine Maleate; Dose-Response Relationship, Drug; Esophageal Sphincter, Lower; Magnesium; Male; Muscle Relaxation; N-Methylaspartate; Nitric Oxide; Potassium Chloride; Rabbits; Receptors, N-Methyl-D-Aspartate; Superoxide Dismutase | 2005 |
Nitric oxide from the laterodorsal tegmental neurons: its possible retrograde modulation on norepinephrine release from the axon terminal of the locus coeruleus neurons.
Topics: Acetylcholine; Animals; Cyclic GMP; Electroencephalography; Electromyography; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Locomotion; Locus Coeruleus; Microdialysis; N-Methylaspartate; Neurons; Nitric Oxide; Nitric Oxide Synthase; Norepinephrine; Polysomnography; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Sleep; Tegmentum Mesencephali | 2006 |
NMDA induces post-transcriptional regulation of alpha2-guanylyl-cyclase-subunit expression in cerebellar granule cells.
Topics: 3' Untranslated Regions; Animals; Base Sequence; Cell Nucleus; Cells, Cultured; Cerebellum; Cyclic GMP; ELAV Proteins; Female; Guanylate Cyclase; Heterogeneous Nuclear Ribonucleoprotein D0; Heterogeneous-Nuclear Ribonucleoprotein D; Male; Molecular Sequence Data; N-Methylaspartate; Nitric Acid; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; RNA Processing, Post-Transcriptional; RNA Stability; RNA, Messenger; Up-Regulation | 2006 |
Modulation of NMDA receptors by AKT kinase.
Topics: Animals; Brain-Derived Neurotrophic Factor; Calcium; Cells, Cultured; Cerebellum; Colforsin; Cyclic GMP; Drug Synergism; Enzyme Activation; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Immunoblotting; Immunoprecipitation; N-Methylaspartate; Neurons; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Proto-Oncogene Proteins c-akt; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate | 2006 |
Cortical feedback to the thalamus is selectively enhanced by nitric oxide.
Topics: Animals; Animals, Newborn; Arginine; Cerebral Cortex; Cyclic GMP; Drug Interactions; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Feedback; Ferrets; Geniculate Bodies; In Vitro Techniques; Male; N-Methylaspartate; Neural Pathways; Neurons; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Penicillamine; Superoxide Dismutase; Synaptic Transmission; Triazoles | 2006 |
Tonic and phasic nitric oxide signals in hippocampal long-term potentiation.
Topics: Analysis of Variance; Animals; Animals, Newborn; Blotting, Western; Cyclic GMP; Dose-Response Relationship, Radiation; Electric Stimulation; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; Hippocampus; In Vitro Techniques; Long-Term Potentiation; Mice; Mice, Inbred C57BL; Mice, Knockout; N-Methylaspartate; Neural Inhibition; Nitric Oxide Synthase Type III; Rats; Rats, Sprague-Dawley; Signal Transduction | 2006 |
Prenatal exposure to polybrominated diphenylether 99 enhances the function of the glutamate-nitric oxide-cGMP pathway in brain in vivo and in cultured neurons.
Topics: Age Factors; Animals; Animals, Newborn; Cells, Cultured; Cerebellum; Cyclic GMP; Dose-Response Relationship, Drug; Drug Interactions; Female; Gene Expression Regulation; Glutamic Acid; Halogenated Diphenyl Ethers; N-Methylaspartate; Neurons; Nitric Oxide; Penicillamine; Phenyl Ethers; Polybrominated Biphenyls; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Wistar; Signal Transduction | 2007 |
Glutamate-induced activation of nitric oxide synthase is impaired in cerebral cortex in vivo in rats with chronic liver failure.
Topics: Ammonia; Animals; Blotting, Western; Cerebral Cortex; Chronic Disease; Cyclic GMP; Enzyme Activation; Fluorescent Antibody Technique, Indirect; Glutamic Acid; Immunohistochemistry; In Vitro Techniques; Liver Failure; Male; N-Methylaspartate; Nitrates; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Nitrites; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction | 2007 |
The function of the glutamate-nitric oxide-cGMP pathway in brain in vivo and learning ability decrease in parallel in mature compared with young rats.
Topics: Aging; Animals; Brain; Cyclic GMP; Female; Glutamic Acid; Immunoblotting; Male; Maze Learning; Microdialysis; N-Methylaspartate; Nitric Oxide; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate | 2007 |
Lipopolysaccharide induces early tolerance to excitotoxicity via nitric oxide and cGMP.
Topics: Animals; Anisomycin; Brain Diseases; Cyclic GMP; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Guanylate Cyclase; Ischemic Preconditioning; Lipopolysaccharides; Male; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; N-Methylaspartate; Neuroprotective Agents; Neurotoxins; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Oxadiazoles; Protein Synthesis Inhibitors; Quinoxalines | 2007 |
Antidepressant-like effect of folic acid: Involvement of NMDA receptors and L-arginine-nitric oxide-cyclic guanosine monophosphate pathway.
Topics: Animals; Antidepressive Agents; Arginine; Cyclic GMP; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Female; Folic Acid; Indazoles; Injections, Intraventricular; Male; Methylene Blue; Mice; N-Methylaspartate; Nitric Oxide; Nitric Oxide Donors; Receptors, N-Methyl-D-Aspartate; S-Nitroso-N-Acetylpenicillamine; Signal Transduction; Swimming; Vitamin B Complex | 2008 |
Physiological effects of NO-cGMP pathway on ovarian steroidogenesis in rat.
Topics: Animals; Cyclic GMP; Female; gamma-Aminobutyric Acid; Gonadotropin-Releasing Hormone; N-Methylaspartate; Nitric Oxide; Norepinephrine; Ovary; Rats; Sexual Maturation; Steroids | 2007 |
Elevated glutamate and NMDA disrupt production of the second messenger cyclic GMP in the early postnatal mouse cortex.
Topics: Animals; Animals, Newborn; Cerebral Cortex; Cyclic GMP; Glutamic Acid; Immunohistochemistry; Mice; N-Methylaspartate; Organ Culture Techniques | 2009 |
NMDA receptor activation increases free radical production through nitric oxide and NOX2.
Topics: Analysis of Variance; Animals; Brain; Cells, Cultured; Cerebrovascular Circulation; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Dizocilpine Maleate; Embryo, Mammalian; Enzyme Inhibitors; Excitatory Amino Acid Agents; Membrane Glycoproteins; Mice; Mice, Inbred C57BL; Mice, Knockout; Microscopy, Immunoelectron; N-Methylaspartate; NADPH Oxidase 2; NADPH Oxidases; Neurons; Nitric Oxide; Nitric Oxide Synthase Type I; Reactive Oxygen Species; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Synapses | 2009 |
Polychlorinated biphenyls PCB 153 and PCB 126 impair the glutamate-nitric oxide-cGMP pathway in cerebellar neurons in culture by different mechanisms.
Topics: Animals; Animals, Newborn; Calcium; Cell Survival; Cells, Cultured; Cerebellum; Cyclic GMP; Dose-Response Relationship, Drug; Excitatory Amino Acid Agents; Glutamic Acid; N-Methylaspartate; Neurons; Neurotoxins; Nitric Oxide; Polychlorinated Biphenyls; Rats; Rats, Wistar; Signal Transduction; Time Factors | 2009 |
More than a retrograde messenger: nitric oxide needs two cGMP pathways to induce hippocampal long-term potentiation.
Topics: Animals; Cyclic GMP; Electric Stimulation; Excitatory Postsynaptic Potentials; Female; Guanylate Cyclase; Hippocampus; In Vitro Techniques; Long-Term Potentiation; Male; Mice; Mice, Knockout; N-Methylaspartate; Nitric Oxide; Patch-Clamp Techniques; Receptors, Cytoplasmic and Nuclear; Signal Transduction; Soluble Guanylyl Cyclase; Synapses | 2009 |
Metabotropic glutamate receptor 5, but not 1, modulates NMDA receptor-mediated activation of neuronal nitric oxide synthase.
Topics: Animals; Arginine; Blotting, Western; Calcium; Cells, Cultured; Cerebellum; Citrulline; Cyclic AMP; Cyclic GMP; Enzyme Activation; Excitatory Amino Acid Agonists; Guanylate Cyclase; N-Methylaspartate; Neurons; Nitrates; Nitric Oxide Synthase Type I; Nitrites; Oncogene Protein v-akt; Rats; Rats, Wistar; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate | 2010 |
Ca2+ influx through NMDA-gated channels activates ATP-sensitive K+ currents through a nitric oxide-cGMP pathway in subthalamic neurons.
Topics: Action Potentials; Animals; Barium; Calcium; Cyclic GMP; Ion Channel Gating; KATP Channels; Male; N-Methylaspartate; Neural Conduction; Neurons; Nitric Oxide; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Subthalamic Nucleus | 2010 |
Developmental exposure to polychlorinated biphenyls 52, 138 or 180 affects differentially learning or motor coordination in adult rats. Mechanisms involved.
Topics: Animals; Cerebellum; Cyclic GMP; Discrimination, Psychological; Environmental Pollutants; Extracellular Space; Female; gamma-Aminobutyric Acid; Glutamic Acid; Learning; Male; Maternal Exposure; Maze Learning; N-Methylaspartate; Polychlorinated Biphenyls; Pregnancy; Prenatal Exposure Delayed Effects; Psychomotor Performance; Rats; Receptors, N-Methyl-D-Aspartate; Sex Factors | 2010 |
Differential modulation of the glutamate-nitric oxide-cyclic GMP pathway by distinct neurosteroids in cerebellum in vivo.
Topics: Animals; Cerebellum; Cyclic GMP; Dehydroepiandrosterone; gamma-Aminobutyric Acid; Glutamic Acid; Male; N-Methylaspartate; Neurotransmitter Agents; Nitric Oxide; Pregnanolone; Pregnenolone; Rats; Rats, Wistar; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Signal Transduction | 2011 |
Involvement of nitric oxide-cGMP pathway in the antidepressant-like effect of ascorbic acid in the tail suspension test.
Topics: Animals; Antidepressive Agents; Arginine; Ascorbic Acid; Cyclic GMP; Depression; Disease Models, Animal; Dizocilpine Maleate; Enzyme Inhibitors; Exploratory Behavior; Female; Hindlimb Suspension; Indazoles; Mice; N-Methylaspartate; Nitric Oxide; Oxadiazoles; Piperazines; Purines; Quinoxalines; Signal Transduction; Sildenafil Citrate; Sulfones | 2011 |
Repeated exposure of adult rats to Aroclor 1254 induces neuronal injury and impairs the neurochemical manifestations of the NMDA receptor-mediated intracellular signaling in the hippocampus.
Topics: Amino Acids; Animals; Calcium Isotopes; Chlorodiphenyl (54% Chlorine); Cyclic GMP; Environmental Pollutants; Excitatory Amino Acid Agonists; Hippocampus; Male; Microdialysis; Microscopy, Electron, Transmission; N-Methylaspartate; Neurons; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Signal Transduction | 2012 |
Guanosine produces an antidepressant-like effect through the modulation of NMDA receptors, nitric oxide-cGMP and PI3K/mTOR pathways.
Topics: Analysis of Variance; Animals; Antidepressive Agents; Arginine; Cyclic GMP; Depression; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Excitatory Amino Acid Agents; Exploratory Behavior; Female; Freezing Reaction, Cataleptic; Guanosine; Hindlimb Suspension; Immunosuppressive Agents; Male; Mice; N-Methylaspartate; Nitric Oxide; Phosphatidylinositol 3-Kinases; Receptors, N-Methyl-D-Aspartate; Serine; Signal Transduction; Sirolimus; Swimming; TOR Serine-Threonine Kinases | 2012 |
Hyperammonemia alters the modulation by different neurosteroids of the glutamate-nitric oxide-cyclic GMP pathway through NMDA- GABAA - or sigma receptors in cerebellum in vivo.
Topics: Animals; Cerebellum; Citrulline; Cyclic GMP; Extracellular Space; Glutamic Acid; Hyperammonemia; Male; N-Methylaspartate; Neurotransmitter Agents; Nitric Oxide; Nitric Oxide Synthase Type I; Rats; Rats, Wistar; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Receptors, sigma | 2013 |
The dorsolateral periaqueductal grey N-methyl-D-aspartate/nitric oxide/cyclic guanosine monophosphate pathway modulates the expression of contextual fear conditioning in rats.
Topics: Animals; Conditioning, Psychological; Cyclic GMP; Fear; Heart; Male; N-Methylaspartate; Nitric Oxide; Nitric Oxide Synthase; Periaqueductal Gray; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Signal Transduction | 2014 |
Elevated intracranial dopamine impairs the glutamate‑nitric oxide‑cyclic guanosine monophosphate pathway in cortical astrocytes in rats with minimal hepatic encephalopathy.
Topics: Animals; Astrocytes; Behavior, Animal; Calmodulin; Cerebral Cortex; Cyclic GMP; Disease Models, Animal; Dopamine; Dose-Response Relationship, Drug; Glial Fibrillary Acidic Protein; Glutamates; Guanylate Cyclase; Hepatic Encephalopathy; Memory; N-Methylaspartate; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Soluble Guanylyl Cyclase | 2014 |
Source memory in rats is impaired by an NMDA receptor antagonist but not by PSD95-nNOS protein-protein interaction inhibitors.
Topics: Aminosalicylic Acids; Animals; Benzylamines; Cells, Cultured; Chlorophenols; Cyclic GMP; Disease Models, Animal; Disks Large Homolog 4 Protein; Dizocilpine Maleate; Embryo, Mammalian; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Hippocampus; Intracellular Signaling Peptides and Proteins; Male; Maze Learning; Membrane Proteins; Memory Disorders; N-Methylaspartate; Neurons; Nitric Oxide Synthase Type I; Rats; Rats, Long-Evans; Triazoles | 2016 |
Contribution of NMDA, GABAA and GABAB receptors and l-arginine-NO-cGMP, MEK1/2 and CaMK-II pathways in the antidepressant-like effect of 7-fluoro-1,3-diphenylisoquinoline-1-amine in mice.
Topics: Animals; Antidepressive Agents; Arginine; Biological Transport; Cyclic GMP; Glutamic Acid; Locomotion; Male; MAP Kinase Kinase 1; MAP Kinase Kinase 2; Mice; N-Methylaspartate; Nitric Oxide; Quinolines; Receptors, GABA-A; Receptors, GABA-B; Receptors, N-Methyl-D-Aspartate; Signal Transduction | 2016 |
Antidepressant effect of pramipexole in mice forced swimming test: A cross talk between dopamine receptor and NMDA/nitric oxide/cGMP pathway.
Topics: Animals; Antidepressive Agents; Arginine; Benzothiazoles; Cyclic GMP; Dizocilpine Maleate; Haloperidol; Immobilization; Injections, Intraperitoneal; Male; Methylene Blue; Mice; Motor Activity; N-Methylaspartate; NG-Nitroarginine Methyl Ester; Nitric Oxide; Pramipexole; Receptors, Dopamine; Signal Transduction; Sildenafil Citrate; Swimming | 2016 |
Nitric oxide-coupled signaling in odor elicited molecular events in the olfactory center of the terrestrial snail, Helix pomatia.
Topics: Animals; Cyclic GMP; Glutamic Acid; Helix, Snails; Models, Biological; N-Methylaspartate; Neurons; Nitric Oxide; Odorants; Olfactory Bulb; Phosphorylation; Receptors, N-Methyl-D-Aspartate; Signal Transduction | 2017 |
Yueju-Ganmaidazao Decoction confers rapid antidepressant-like effects and the involvement of suppression of NMDA/NO/cGMP signaling.
Topics: Animals; Antidepressive Agents; Cyclic GMP; Depression; Drugs, Chinese Herbal; Mice; N-Methylaspartate; Nitric Oxide; Signal Transduction | 2020 |
Antidepressant-like effect of ethanol in mice forced swimming test is mediated via inhibition of NMDA/nitric oxide/cGMP signaling pathway.
Topics: Animals; Antidepressive Agents; Arginine; Cyclic GMP; Depression; Ethanol; Mice; N-Methylaspartate; Nitric Oxide; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Swimming | 2021 |
Hippocampal AMPA- and NMDA-induced cGMP signals are mainly generated by NO-GC2 and are under tight control by PDEs 1 and 2.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cyclic GMP; Hippocampus; Mice; N-Methylaspartate; Nitric Oxide; Phosphoric Diester Hydrolases; Protein Isoforms | 2022 |
Hyperammonemia Alters the Function of AMPA and NMDA Receptors in Hippocampus: Extracellular cGMP Reverses Some of These Alterations.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cyclic GMP; Hippocampus; Hyperammonemia; N-Methylaspartate; Rats; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate | 2022 |
Mechanistic pathways of fibromyalgia induced by intermittent cold stress in mice is sex-dependently.
Topics: Adenosine Triphosphatases; Animals; Arginine; Cold-Shock Response; Cyclic GMP; Dizocilpine Maleate; Female; Fibromyalgia; Male; Methylene Blue; Mice; N-Methylaspartate; Nitric Oxide; Quality of Life; Receptors, N-Methyl-D-Aspartate | 2022 |