n-methylaspartate and colforsin

Topics: Animals; Drug Design; Humans; Receptors, Drug

Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Calcium; Cesium; Colforsin; Glycine; Ibotenic Acid; In Vitro Techniques; N-Methylaspartate; Neurokinin A; Neurons; Peptides; Phorbol Esters; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Substance P; Tachykinins

Topics: 8-Bromo Cyclic Adenosine Monophosphate; Alkaloids; Amino Acid Sequence; Animals; Base Sequence; Cloning, Molecular; Colforsin; Diterpenes; Enzyme Activation; Female; Genetic Variation; Kinetics; Ligands; Molecular Sequence Data; N-Methylaspartate; Oligodeoxyribonucleotides; Oocytes; Polyamines; Protein Kinase C; Protein Kinase Inhibitors; Protein Kinases; Rats; Receptors, N-Methyl-D-Aspartate; RNA Splicing; Sphingosine; Staurosporine; Terpenes; Tetradecanoylphorbol Acetate; Xenopus laevis

Topics: Animals; Bucladesine; Calcium; Colforsin; Cyclic AMP; Enzyme Activation; Hippocampus; N-Methylaspartate; Neurons; Protein Kinase C; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate

Topics: Adenosine Triphosphate; Animals; Animals, Newborn; Cells, Cultured; Colforsin; Electric Conductivity; Glutamates; Hippocampus; Ion Channel Gating; Ion Channels; Kainic Acid; Kinetics; Membrane Potentials; N-Methylaspartate; Neurons; Protein Kinases; Rats; Receptors, Glutamate; Receptors, Neurotransmitter

Topics: Animals; Aspartic Acid; Calcineurin; Calmodulin-Binding Proteins; Colforsin; Corpus Striatum; Cyclic AMP; Dibenzocycloheptenes; Dizocilpine Maleate; Dopamine and cAMP-Regulated Phosphoprotein 32; Enzyme Activation; N-Methylaspartate; Nerve Tissue Proteins; Phosphates; Phosphoprotein Phosphatases; Phosphoproteins; Phosphorylation; Phosphothreonine; Protein Kinases; Protein Phosphatase 1; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine

Topics: Action Potentials; Amino Acids; Animals; Aspartic Acid; Calcium; Colforsin; Drug Synergism; Glutamates; Glutamic Acid; N-Methylaspartate; Neurons; Phorbol Esters; Rats; Rats, Inbred Strains; Sodium; Spinal Cord; Synapses; Synaptic Transmission

Topics: Adenosine; Amino Acids; Animals; Aspartic Acid; Chlorides; Colforsin; Cyclic AMP; Cysteine; Drug Interactions; Ethylmaleimide; Glutamates; Glutamic Acid; Guanosine Triphosphate; Guinea Pigs; Hippocampus; Histamine; Male; N-Methylaspartate; Neurotransmitter Agents; Veratridine

Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Animals; Calcium; Chromatography, High Pressure Liquid; Colforsin; Cyclic AMP; Excitatory Amino Acids; Male; N-Methylaspartate; Parietal Lobe; Probenecid; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate

Topics: Animals; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Excitatory Amino Acid Agonists; Male; N-Methylaspartate; Neostriatum; Neurons; Rats; Rats, Sprague-Dawley; Synaptic Transmission

Topics: 2-Amino-5-phosphonovalerate; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; 6-Cyano-7-nitroquinoxaline-2,3-dione; Adenylyl Cyclases; Animals; Ascorbic Acid; Calcium; Calmodulin; Cell Membrane; Colforsin; Cyclic AMP; Deoxyadenosines; Dopamine; Enzyme Activation; Evoked Potentials; Glycine; Hippocampus; In Vitro Techniques; Isoproterenol; Kinetics; Models, Neurological; N-Methylaspartate; Pyramidal Tracts; Quinoxalines; Rats; Receptors, N-Methyl-D-Aspartate; Sulfonamides; Theophylline; Trifluoperazine

Topics: Animals; Cerebellum; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Female; In Vitro Techniques; Isoquinolines; Male; N-Methylaspartate; Nitric Oxide; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Sulfonamides

Topics: Animals; Calcium; Cell Survival; Cells, Cultured; Cerebral Cortex; Colforsin; Cyclic AMP; Cycloleucine; Hydrolysis; L-Lactate Dehydrogenase; Mice; N-Methylaspartate; Neurons; Phosphatidylinositols; Receptors, Metabotropic Glutamate; Second Messenger Systems

Topics: Animals; Arterioles; Asphyxia; Cerebrovascular Circulation; Colforsin; Hypercapnia; N-Methylaspartate; Pia Mater; Respiration, Artificial; Swine; Vasodilation

Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Astrocytes; Biotransformation; Cells, Cultured; Cerebral Cortex; Colforsin; Cyclic AMP; Excitatory Amino Acid Agonists; Excitatory Amino Acids; Extracellular Space; Mice; N-Methylaspartate; Nerve Degeneration; Neuroglia; Neurons; Receptors, Metabotropic Glutamate

Topics: Animals; Azetidinecarboxylic Acid; Benzoates; Cells, Cultured; Colforsin; Cyclic AMP; Epithelial Cells; Epithelium; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Hippocampus; Hydrolysis; Inositol Phosphates; Kidney; Long-Term Potentiation; Male; N-Methylaspartate; Organ Culture Techniques; Patch-Clamp Techniques; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Swine; Temperature; Transfection

Topics: Amyloid beta-Peptides; Animals; Cells, Cultured; Cerebral Cortex; Colforsin; Dizocilpine Maleate; Female; Hippocampus; N-Methylaspartate; Neurons; Neuroprotective Agents; Pregnancy; Rats; Rats, Wistar; Sulfonamides; Thiazoles

Topics: Adenylyl Cyclases; Animals; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Electric Stimulation; Enzyme Activation; Enzyme Inhibitors; Hippocampus; In Vitro Techniques; Long-Term Potentiation; Male; N-Methylaspartate; Rats; Rats, Sprague-Dawley; Signal Transduction; Time Factors

Topics: Adenylate Cyclase Toxin; Animals; Colforsin; Cyclic AMP-Dependent Protein Kinases; Dentate Gyrus; Electric Stimulation; Enzyme Inhibitors; In Vitro Techniques; Male; N-Methylaspartate; Neurons; Pertussis Toxin; Phosphorylation; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Synaptic Transmission; Virulence Factors, Bordetella

Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Brain Stem; Buffers; Calcium; Colforsin; Cyclic AMP; Enzyme Inhibitors; Excitatory Amino Acid Agonists; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Hippocampus; Male; N-Methylaspartate; Neurons; Oxytocin; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Thionucleotides; Vagus Nerve

Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain Ischemia; Calcium; Capillaries; Cattle; Cells, Cultured; Cerebrovascular Circulation; Colforsin; Cyclic AMP; Cycloleucine; Endothelin-1; Endothelium, Vascular; Gene Expression; Humans; Inositol 1,4,5-Trisphosphate; Kainic Acid; Mice; N-Methylaspartate; Neurons; Polymerase Chain Reaction; Rats; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Second Messenger Systems

Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Animals, Newborn; Basal Ganglia; Benzazepines; Calcium; Calcium Channels; Calcium Channels, L-Type; Colforsin; Corpus Striatum; Cyclic AMP Response Element-Binding Protein; Dopamine Agonists; Kinetics; N-Methylaspartate; Organ Culture Techniques; Organ Specificity; Phosphorylation; Rats; Rats, Sprague-Dawley; Time Factors

Topics: 1-Methyl-3-isobutylxanthine; Animals; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Glioma; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Hybrid Cells; Kinetics; Mice; N-Methylaspartate; Narcotic Antagonists; Neuroblastoma; Neurons; Nociceptin; Nociceptin Receptor; Opioid Peptides; Rats; Receptors, Opioid; Signal Transduction

Topics: Animals; Apoptosis; Carbachol; Cell Survival; Cells, Cultured; Central Nervous System Depressants; Cerebellum; Colforsin; Drug Interactions; Ethanol; Excitatory Amino Acid Agonists; gamma-Aminobutyric Acid; Microscopy, Electron; Muscarinic Agonists; N-Methylaspartate; Neurons; Potassium; Rats; Rats, Sprague-Dawley

Topics: Action Potentials; Animals; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Electric Stimulation; Enzyme Activation; Hippocampus; In Vitro Techniques; Male; N-Methylaspartate; Phosphorylation; Rats; Rats, Long-Evans; Receptors, AMPA; Synapses; Synaptic Transmission; Thionucleotides

Topics: Animals; Anticonvulsants; Brain; Cell Line; Cell Membrane; Colforsin; Corpus Striatum; Cyclic AMP; Electroshock; Glutamic Acid; Glycine; Humans; Kinetics; Male; Mice; Mice, Inbred Strains; N-Methylaspartate; Neuroprotective Agents; Phosphatidylinositols; Protein Isoforms; Quinolinic Acid; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Recombinant Proteins; Second Messenger Systems; Seizures; Structure-Activity Relationship

Topics: Animals; Animals, Newborn; Arterioles; Calcitonin Gene-Related Peptide; Cerebral Cortex; Cerebrovascular Circulation; Colforsin; Cortical Spreading Depression; Female; Hypercapnia; Male; N-Methylaspartate; Picolines; Pyrans; Swine; Vasodilation

Topics: Adenylyl Cyclases; Analgesics, Opioid; Animals; Cardiovascular Agents; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Electrophysiology; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enzyme Inhibitors; Excitatory Amino Acid Agonists; gamma-Aminobutyric Acid; In Vitro Techniques; Interneurons; Isoquinolines; Male; Membrane Potentials; Morphine; N-Methylaspartate; Neural Inhibition; Periaqueductal Gray; Phenylephrine; Pyrimidines; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Serotonin; Substance Withdrawal Syndrome; Sulfonamides; Sympathomimetics; Tetrazoles; Tetrodotoxin; Thionucleotides

Topics: Animals; Calcium; Calcium Channel Blockers; Cells, Cultured; Colforsin; Critical Period, Psychological; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Excitatory Amino Acid Agonists; Hippocampus; MAP Kinase Signaling System; Membrane Potentials; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; N-Methylaspartate; Neuronal Plasticity; Neurons; Nimodipine; Phosphoprotein Phosphatases; Phosphorylation; Potassium Chloride; Rats; Receptors, N-Methyl-D-Aspartate

Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Antibody Specificity; Catalytic Domain; Caudate Nucleus; Colforsin; Dihydroxyphenylalanine; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Glutamic Acid; In Vitro Techniques; Male; N-Methylaspartate; Neurons; Okadaic Acid; Oxidopamine; Phosphorylation; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Serine; Sympatholytics; Tyrosine 3-Monooxygenase

Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Colforsin; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Female; Hypothalamus; Isoquinolines; Kinetics; Marine Toxins; N-Methylaspartate; Oocytes; Oxazoles; Phosphoprotein Phosphatases; Protein Kinase C; Protein Phosphatase 1; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Recombinant Proteins; RNA, Messenger; Sulfonamides; Xenopus laevis

Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Colforsin; Corpus Striatum; Dihydroxyphenylalanine; Dopamine; Dopamine Agonists; Male; N-Methylaspartate; Nerve Tissue Proteins; Okadaic Acid; Phosphodiesterase Inhibitors; Phosphoprotein Phosphatases; Phosphorylation; Phosphoserine; Protein Phosphatase 1; Protein Processing, Post-Translational; Quinpirole; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Tyrosine 3-Monooxygenase

Topics: Adenoviridae; Animals; Brain-Derived Neurotrophic Factor; Calcium; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Genes, Dominant; Hippocampus; Ionophores; Mitogen-Activated Protein Kinases; N-Methylaspartate; Nerve Growth Factors; Neurons; Phosphorylation; rap1 GTP-Binding Proteins; ras GTPase-Activating Proteins; ras Proteins; Rats; Signal Transduction; Transfection

Topics: 2-Amino-5-phosphonovalerate; Animals; Animals, Newborn; Apoptosis; Cell Differentiation; Cell Survival; Cells, Cultured; Cerebellar Cortex; Colforsin; Cyclic AMP Response Element-Binding Protein; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Immunohistochemistry; N-Methylaspartate; Neurons; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission

Topics: Adenylyl Cyclases; Animals; Animals, Newborn; Blotting, Western; Brain-Derived Neurotrophic Factor; Cell Nucleus; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Electrophysiology; Enzyme Activation; Hippocampus; Immunohistochemistry; Mice; Mice, Inbred C57BL; Models, Biological; N-Methylaspartate; Neurons; Neuropeptides; Peptides; Phosphorylation; Pituitary Adenylate Cyclase-Activating Polypeptide; Precipitin Tests; Protein Binding; Protein Structure, Tertiary; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fyn; Rats; Rats, Sprague-Dawley; Receptors for Activated C Kinase; Receptors, N-Methyl-D-Aspartate; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Time Factors; Tyrosine

Topics: Acetylcysteine; Analysis of Variance; Animals; Animals, Newborn; Blotting, Western; Calcium; Cells, Cultured; Colforsin; Cysteine Proteinase Inhibitors; Disks Large Homolog 4 Protein; Drug Interactions; Electric Stimulation; Embryo, Mammalian; Endocytosis; Epitopes; Excitatory Amino Acid Agonists; Hippocampus; Humans; Immunoglobulin G; Immunohistochemistry; Immunosuppressive Agents; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; Kidney; Leupeptins; Membrane Potentials; Membrane Proteins; Mutation; N-Methylaspartate; Nerve Tissue Proteins; Neural Inhibition; Neurons; Nuclear Proteins; Patch-Clamp Techniques; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-mdm2; Rats; Rats, Long-Evans; Receptors, AMPA; Synapses; Synapsins; Tacrolimus; Time Factors; Transfection; Ubiquitin

Topics: Animals; Arachidonic Acids; Bicuculline; Cannabinoid Receptor Modulators; Colforsin; Cyclic AMP; Endocannabinoids; Ethanol; Gonadotropin-Releasing Hormone; Hypothalamus, Middle; Kinetics; Male; N-Methylaspartate; Naltrexone; Polyunsaturated Alkamides; Radioimmunoassay; Rats; Rats, Wistar

Topics: 2-Amino-5-phosphonovalerate; Animals; Benzimidazoles; Butadienes; Calcium-Calmodulin-Dependent Protein Kinase Kinase; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Colforsin; Excitatory Amino Acid Antagonists; Hippocampus; Isoquinolines; Long-Term Potentiation; Male; Mice; Mice, Inbred C57BL; Mitogen-Activated Protein Kinase 1; Mutation, Missense; N-Methylaspartate; Naphthalimides; Neurons; Nitriles; Protein Kinase Inhibitors; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; ras-GRF1; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Recombinant Fusion Proteins

Topics: Adenosine; Adenosine A2 Receptor Agonists; Animals; Bicuculline; Blotting, Western; Colforsin; Disks Large Homolog 4 Protein; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Embryo, Mammalian; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; Female; Fluorescent Antibody Technique; GABA Antagonists; Glycine; Hippocampus; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; Male; Membrane Proteins; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Phenethylamines; Phenylacetates; Pregnancy; Presynaptic Terminals; Pyridines; Qa-SNARE Proteins; Rats; Rats, Wistar; Receptor, Metabotropic Glutamate 5; Receptors, Adenosine A2; Receptors, Metabotropic Glutamate; Synaptophysin; Vesicular Glutamate Transport Protein 1

Topics: Animals; Binding Sites; Biotinylation; Blotting, Western; Colforsin; Electrophysiology; Hippocampus; Long-Term Potentiation; Male; N-Methylaspartate; Neuronal Plasticity; Neurons; Phosphorylation; Protein Structure, Tertiary; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Rolipram; Serine; Synaptic Transmission; Time Factors

Topics: Action Potentials; Animals; Cadmium; Calcium; Calcium Channels; Cerebellum; Colforsin; Cyclopropanes; Excitatory Postsynaptic Potentials; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Interneurons; N-Methylaspartate; Nickel; Patch-Clamp Techniques; Presynaptic Terminals; Purkinje Cells; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Synaptic Vesicles

Topics: Animals; Brain-Derived Neurotrophic Factor; Calcium; Cells, Cultured; Cerebellum; Colforsin; Cyclic GMP; Drug Synergism; Enzyme Activation; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Immunoblotting; Immunoprecipitation; N-Methylaspartate; Neurons; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Proto-Oncogene Proteins c-akt; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate

Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Bacterial Proteins; Blotting, Western; Cells, Cultured; Colforsin; Cyclic AMP-Dependent Protein Kinases; Cytoskeletal Proteins; Fluorescent Antibody Technique; Gene Expression; GTP-Binding Protein alpha Subunits, Gs; Luminescent Proteins; Microscopy, Fluorescence; N-Methylaspartate; Nerve Tissue Proteins; Protein Biosynthesis; Rats; Receptors, N-Methyl-D-Aspartate; Recombinant Fusion Proteins; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Transfection

Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Action Potentials; Age Factors; Animals; Behavior, Animal; Brain; Bupropion; Colforsin; Dopamine; Dopamine Agents; Dopamine Uptake Inhibitors; Electric Stimulation; Larva; N-Methylaspartate; Neural Inhibition; Neurons; Patch-Clamp Techniques; Probability; Spinal Cord; Swimming; Time Factors; Tyrosine 3-Monooxygenase; Zebrafish

Topics: Analysis of Variance; Animals; Brain-Derived Neurotrophic Factor; Cell Count; Cell Culture Techniques; Ciliary Neurotrophic Factor; Colforsin; Culture Media; Dose-Response Relationship, Drug; Erythropoietin; Fibroblast Growth Factor 2; Immunohistochemistry; Microscopy, Fluorescence; N-Methylaspartate; Rats; Retinal Ganglion Cells; Toxicity Tests; Tumor Necrosis Factor-alpha

Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Afferent Pathways; Amidines; Amphetamine-Related Disorders; Animals; Benzophenanthridines; Central Nervous System Stimulants; Chronic Disease; Colforsin; Dextroamphetamine; Excitatory Amino Acid Agonists; Female; Glutamic Acid; Isoquinolines; N-Methylaspartate; Oxidants; Protein Kinase Inhibitors; Rats, Wistar; Reflex; Spinal Cord; Sulfonamides; Urinary Retention; Urination; Valine