Compounds > n-methylaspartate
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n-methylaspartate and carbostyril

n-methylaspartate has been researched along with carbostyril in 14 studies

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (35.71)18.2507
2000's5 (35.71)29.6817
2010's3 (21.43)24.3611
2020's1 (7.14)2.80

Authors

AuthorsStudies
Aizenman, E; Gallop, PM; Jensen, FE; Rosenberg, PA; Tang, LH1
Cordi, AA; Desos, P; Lepagnol, JM; Lestage, P; Morain, P1
Erdõ, SL; Molnár, P1
Baker, R; Carling, RW; Duncton, M; Foster, AC; Grimwood, S; Hudson, ML; Kemp, JA; Leeson, PD; Marshall, GR; Moore, KW; Moyes, CR; Saywell, KL; Tricklebank, MD1
Behl, B; Hofmann, HP; Löscher, W; Potschka, H; Szabo, L; Treiber, HJ; Wlaź, P1
Balster, RL; Wiley, JL1
Chizh, BA; Christoph, T; Englberger, W; Reissmüller, E; Schiene, K1
Adamcio, B; Belozertseva, I; Bespalov, A; Dravolina, O; Zvartau, E1
Ando, K; Fujita, I; Hattori, K; Hirota, M; Hizue, M; Kawai, M; Kawamura, M; Matsumoto, Y; Mizutani, M; Nakamura, H; Ohta, A; Sakurada, I; Sudo, M; Takashima, T; Watanabe, S1
Freichel, C; Künnecke, B; Maco, M; Moreau, JL; Nordquist, RE; Riemer, C; Risterucci, C; Spooren, W; von Kienlin, M1
Bevins, RA; Murray, JE; Polewan, RJ; Walker, AW1
Dudka, J; Oniszczuk, T; Poleszak, E; Serefko, A; Szopa, A; Wlaź, P; Wośko, S; Wróbel, A1
Johnson, SW; Wu, YN1
Bading, H; Bas-Orth, C; Bengtson, CP; Hagenston, AM; Merz, SF; Tepohl, C1

Other Studies

14 other study(ies) available for n-methylaspartate and carbostyril

ArticleYear
Further evidence that pyrroloquinoline quinone interacts with the N-methyl-D-aspartate receptor redox site in rat cortical neurons in vitro.
    Neuroscience letters, 1994, Feb-28, Volume: 168, Issue:1-2

    Topics: Animals; Cells, Cultured; Cerebral Cortex; Coenzymes; Dithionitrobenzoic Acid; Electric Conductivity; Embryo, Mammalian; Ethylmaleimide; Ion Channel Gating; Ion Channels; N-Methylaspartate; Neurons; Oxidation-Reduction; PQQ Cofactor; Quinolones; Rats; Receptors, N-Methyl-D-Aspartate

1994
Structure-activity relationships in a series of 2(1H)-quinolones bearing different acidic function in the 3-position: 6,7-dichloro-2(1H)-oxoquinoline-3-phosphonic acid, a new potent and selective AMPA/kainate antagonist with neuroprotective properties.
    Journal of medicinal chemistry, 1996, Jan-05, Volume: 39, Issue:1

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain; Brain Ischemia; Electrophysiology; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Gerbillinae; Kainic Acid; Mice; Molecular Structure; N-Methylaspartate; Neuroprotective Agents; Organophosphonates; Quinolones; Quinoxalines; Rats; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Structure-Activity Relationship; Xenopus

1996
Differential effects of five glycine site antagonists on NMDA receptor desensitisation.
    European journal of pharmacology, 1996, Sep-12, Volume: 311, Issue:2-3

    Topics: Animals; Benzothiadiazines; Cells, Cultured; Cerebral Cortex; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Glycine; Kynurenic Acid; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Quinolones; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate

1996
4-substituted-3-phenylquinolin-2(1H)-ones: acidic and nonacidic glycine site N-methyl-D-aspartate antagonists with in vivo activity.
    Journal of medicinal chemistry, 1997, Feb-28, Volume: 40, Issue:5

    Topics: Aminoquinolines; Animals; Anticonvulsants; Binding Sites; Binding, Competitive; Brain; Excitatory Amino Acid Antagonists; Glycine; Magnetic Resonance Spectroscopy; Mass Spectrometry; Mice; Mice, Inbred DBA; Molecular Structure; N-Methylaspartate; Quinolones; Rats; Receptors, N-Methyl-D-Aspartate; Structure-Activity Relationship

1997
LU 73068, a new non-NMDA and glycine/NMDA receptor antagonist: pharmacological characterization and comparison with NBQX and L-701,324 in the kindling model of epilepsy.
    British journal of pharmacology, 1998, Volume: 125, Issue:6

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anticonvulsants; Disease Models, Animal; Dizocilpine Maleate; Drug Synergism; Epilepsy; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Imidazoles; Kindling, Neurologic; Male; Mice; Mice, Inbred Strains; N-Methylaspartate; Quinolones; Quinoxalines; Receptors, AMPA; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Tritium

1998
Effects of modulators of N-methyl-D-aspartate receptor-mediated neurotransmission on diazepam discrimination in rats.
    Life sciences, 2004, May-28, Volume: 75, Issue:2

    Topics: Amino Acids; Animals; Biguanides; Binding Sites; Conditioning, Operant; Diazepam; Discrimination, Psychological; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; GABA Agonists; Male; N-Methylaspartate; Pentobarbital; Phencyclidine; Piperazines; Quinolones; Quinoxalines; Rats; Rats, Sprague-Dawley; Riluzole

2004
Antiallodynic effects of NMDA glycine(B) antagonists in neuropathic pain: possible peripheral mechanisms.
    Brain research, 2005, Jun-28, Volume: 1048, Issue:1-2

    Topics: Action Potentials; Animals; Constriction, Pathologic; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Routes; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Kynurenic Acid; Ligation; Male; N-Methylaspartate; Neuralgia; Neurons, Afferent; Pain Measurement; Quinolones; Rats; Rats, Sprague-Dawley; Spinal Cord; Spinal Nerves; Time Factors

2005
Lowered brain stimulation reward thresholds in rats treated with a combination of caffeine and N-methyl-D-aspartate but not alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate or metabotropic glutamate receptor-5 receptor antagonists.
    Behavioural pharmacology, 2006, Volume: 17, Issue:4

    Topics: Animals; Benzodiazepines; Brain; Caffeine; Central Nervous System Stimulants; Conditioning, Operant; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Synergism; Electric Stimulation; Excitatory Amino Acid Antagonists; Male; N-Methylaspartate; Piperazines; Pyridines; Quinolones; Rats; Rats, Wistar; Receptor, Adenosine A2A; Receptor, Metabotropic Glutamate 5; Receptors, AMPA; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Reward; Self Stimulation; Ventral Tegmental Area

2006
Discovery of (-)-6-[2-[4-(3-fluorophenyl)-4-hydroxy-1-piperidinyl]-1-hydroxyethyl]-3,4-dihydro-2(1H)-quinolinone--a potent NR2B-selective N-methyl D-aspartate (NMDA) antagonist for the treatment of pain.
    Bioorganic & medicinal chemistry letters, 2007, Oct-15, Volume: 17, Issue:20

    Topics: Animals; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2D6 Inhibitors; Enzyme Inhibitors; Ether-A-Go-Go Potassium Channels; Inhibitory Concentration 50; Molecular Structure; N-Methylaspartate; Pain; Piperidines; Quinolones; Rats; Receptors, N-Methyl-D-Aspartate; Structure-Activity Relationship

2007
Effects of aripiprazole/OPC-14597 on motor activity, pharmacological models of psychosis, and brain activity in rats.
    Neuropharmacology, 2008, Volume: 54, Issue:2

    Topics: Animals; Antipsychotic Agents; Apomorphine; Aripiprazole; Brain; Catalepsy; Data Interpretation, Statistical; Dopamine Agonists; Hallucinogens; Image Processing, Computer-Assisted; Magnetic Resonance Imaging; Male; Motor Activity; N-Methylaspartate; Piperazines; Postural Balance; Psychoses, Substance-Induced; Quinolones; Rats; Rats, Sprague-Dawley; Reflex, Startle; Serotonin Receptor Agonists

2008
An examination of NMDA receptor contribution to conditioned responding evoked by the conditional stimulus effects of nicotine.
    Psychopharmacology, 2011, Volume: 213, Issue:1

    Topics: 2-Amino-5-phosphonovalerate; Animals; Brain; Conditioning, Classical; Cyclopentanes; Discrimination, Psychological; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Antagonists; Male; Mecamylamine; N-Methylaspartate; Nicotine; Phencyclidine; Phenols; Piperazines; Piperidines; Quinolones; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate

2011
NMDA receptor activation antagonizes the NMDA antagonist-induced antianxiety effect in the elevated plus-maze test in mice.
    Pharmacological reports : PR, 2013, Volume: 65, Issue:5

    Topics: 2-Amino-5-phosphonovalerate; Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Binding Sites; Brain; Disease Models, Animal; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Ligands; Male; Maze Learning; Mice; N-Methylaspartate; Quinolones; Receptors, N-Methyl-D-Aspartate; Serine

2013
Memantine selectively blocks extrasynaptic NMDA receptors in rat substantia nigra dopamine neurons.
    Brain research, 2015, Apr-07, Volume: 1603

    Topics: Animals; Dizocilpine Maleate; Dopaminergic Neurons; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Male; Memantine; Membrane Potentials; N-Methylaspartate; Patch-Clamp Techniques; Pyrazoles; Quinolones; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Substantia Nigra; Tissue Culture Techniques

2015
A microscopy-based small molecule screen in primary neurons reveals neuroprotective properties of the FDA-approved anti-viral drug Elvitegravir.
    Molecular brain, 2020, 09-14, Volume: 13, Issue:1

    Topics: Animals; Antiviral Agents; Cell Death; Cells, Cultured; Channelrhodopsins; Drug Approval; Excitatory Postsynaptic Potentials; HEK293 Cells; Humans; Membrane Potential, Mitochondrial; Mice, Inbred C57BL; Microscopy; N-Methylaspartate; Neurons; Neuroprotection; Neuroprotective Agents; Optogenetics; Quinolones; Receptors, AMPA; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Small Molecule Libraries; Synapses; United States; United States Food and Drug Administration

2020