n-methylaspartate has been researched along with arginine in 154 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (1.30) | 18.7374 |
| 1990's | 112 (72.73) | 18.2507 |
| 2000's | 21 (13.64) | 29.6817 |
| 2010's | 14 (9.09) | 24.3611 |
| 2020's | 5 (3.25) | 2.80 |
| Authors | Studies |
|---|---|
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Corasaniti, MT; Finazzi-Agrò, A; Melino, G; Nisticò, G; Tartaglia, RL | 2 |
| Bockaert, J; de Bock, F; Lerner-Natoli, M; Rondouin, G | 1 |
| Haley, JE; Kitto, KF; Wilcox, GL | 1 |
| Boje, KM; Skolnick, P | 1 |
| Dykstra, C; Gebhart, GF; Meller, ST | 1 |
| Dingledine, R; Heinemann, SF; Hume, RI | 1 |
| Costa, E; Kiedrowski, L; Wroblewski, JT | 2 |
| De Francesco, EA; Mollace, V; Nisticó, G | 1 |
| Dolphin, AC; Kobrinsky, EM; Pearson, HA; Pullar, IA; Scott, RH; Sweeney, MI; Timms, GH; Wedley, S | 1 |
| Gribkoff, VK; Lum-Ragan, JT | 1 |
| Arvin, B; Lekieffre, D; Meldrum, B; Moncada, C | 1 |
| Davies, JA; Dickie, BG; Lewis, MJ | 1 |
| Clifford, DB; Izumi, Y; Zorumski, CF | 1 |
| Benz, AM; Clifford, DB; Izumi, Y; Zorumski, CF | 1 |
| East, SJ; Garthwaite, J | 2 |
| Bredt, DS; Dawson, TM; Dawson, VL; London, ED; Snyder, SH | 1 |
| Braquet, P; Chabrier, PE; Demerlé-Pallardy, C; Lonchampt, MO | 1 |
| Baron, BM; Cheng, HC; Doherty, NS; Lambert, LE; McDonald, IA; Whitten, JP | 1 |
| Bagetta, G; Mollace, V; Nisticò, G | 1 |
| De Sarro, A; De Sarro, GB; Donato Di Paola, E; Vidal, MJ | 1 |
| Hiromi, K; Inoue, K; Inoue, Y; Kagamiyama, H; Kuramitsu, S; Morino, Y; Tanase, S | 1 |
| Bredt, DS; Snyder, SH | 1 |
| Cai, Z; Hersey, K; Rhodes, PG; Sigrest, T | 1 |
| Colasanti, M; Lauro, GM; Mollace, V; Nistico, G; Rodino, P; Rotiroti, D | 1 |
| Alagarsamy, S; Johnson, KM; Lonart, G | 1 |
| Knezevich, S; Luo, D; Vincent, SR | 1 |
| Friedlander, MJ; Gancayco, CD; Marchase, RB; Montague, PR; Winn, MJ | 1 |
| Bockaert, J; Culcasi, M; Gaven, F; Lafon-Cazal, M; Pietri, S | 1 |
| Patel, J; Pullan, LM; Stumpo, RJ; Thompson, C; Zinkand, WC | 1 |
| Nicklas, WJ; Zeevalk, GD | 1 |
| Bockaert, J; Culcasi, M; Lafon-Cazal, M; Pietri, S | 1 |
| Hamada, T; Shibata, S; Watanabe, A; Watanabe, S | 1 |
| de Vente, J; Garthwaite, J; Gittins, SR; Morris, R; Southam, E | 1 |
| Black, SM; Bristow, JD; Grumbach, MM; Kaplan, SL; Mahachoklertwattana, P | 1 |
| Binns, KE; Do, KQ; Salt, TE | 1 |
| Björkman, R; Hallman, KM; Hedner, J; Hedner, T; Henning, M | 1 |
| Gebhart, GF; Meller, ST | 1 |
| el-Fakahany, EE; Hu, J; Mahmoud, MI | 1 |
| Cummings, JA; Malenka, RC; Nicola, SM | 1 |
| Chen, D; Ding, JM; Faiman, LE; Gillette, MU; Rea, MA; Weber, ET | 1 |
| Argiolas, A; Melis, MR; Stancampiano, R | 1 |
| Luo, D; Vincent, SR | 1 |
| Acuña, C; Cudeiro, J; Grieve, KL; Martínez-Conde, S; Rivadulla, C; Rodríguez, R | 2 |
| Garthwaite, G; Garthwaite, J | 1 |
| Bockaert, J; Fagni, L; Lafon-Cazal, M; Lerner-Natoli, M; Manzoni, O; Rondouin, G | 1 |
| Beninger, RJ; Boegman, RJ; Connop, BP; Jhamandas, K | 1 |
| Brorson, JR; Marcuccilli, CJ; Miller, RJ | 1 |
| Bhardwaj, A; Hanley, DF; Koehler, RC; Northington, FJ; Stiefel, T; Traystman, RJ | 1 |
| Budai, D; Larson, AA; Wilcox, GL | 1 |
| Chau, A; Khanna, JM; Morato, GS; Shah, G | 1 |
| Doorty, KB; Kollegger, H; McBean, GJ; Tipton, KF | 1 |
| Busto, R; Dietrich, WD; Ginsberg, MD; Globus, MY; Prado, R; Sanchez-Ramos, J; Zhao, W | 1 |
| Chai, CY; Kao, LS; Lin, AM | 1 |
| Koehler, RC; Northington, FJ; Tobin, JR; Traystman, RJ | 1 |
| Kollegger, H; McBean, GJ; Tipton, KF | 1 |
| Henry, JL; Radhakrishnan, V | 1 |
| Baudry, M; Musleh, WY; Shahi, K | 1 |
| Ambrosini, A; Racagni, G | 1 |
| Boulu, RG; Buisson, A; Callebert, J; Margaill, I; Plotkine, M | 1 |
| Kato, K; Zorumski, CF | 1 |
| Hastings, TG; Reynolds, IJ | 1 |
| Babbedge, R; Dray, A; Levers, T; Thompson, SW; Urban, L | 1 |
| Cui, LN; Inenaga, K; Nagatomo, T; Yamashita, H | 1 |
| Argiolas, A | 1 |
| Pike, NV; Wayman, CP; Wilson, JF | 1 |
| Matsuki, N; Saito, H; Tanaka, T | 1 |
| Gebhart, GF; Kolhekar, R; Meller, ST | 1 |
| Furness, LE; Horan, R; Maier, SF; Martinez, J; Watkins, LR; Wiertelak, EP | 1 |
| Amir, S | 1 |
| Ishida, Y; Mitsuyama, Y; Yamamoto, R | 1 |
| Bockaert, J; Lafon-Cazal, M; Marin, P; Quignard, JF | 1 |
| Garaschuk, O; Kovalchuk, Yu; Krishtal, O | 1 |
| Sorkin, LS | 1 |
| Craig, CG; White, TD | 1 |
| Malmberg, AB; Yaksh, TL | 1 |
| Bonavera, JJ; Kalra, PS; Kalra, SP; Sahu, A | 1 |
| Choi, DW; Corbett, JA; Hewett, SJ; McDaniel, ML | 1 |
| De Sarro, A; De Sarro, G; Di Paola, ED; Vidal, MJ | 1 |
| Reif, DW | 1 |
| Johnston, MV; Taylor, GA; Traystman, RJ; Trescher, WH | 1 |
| Felipo, V; Grisolía, S; Marcaida, G; Miñana, MD | 1 |
| Carter, C; Fage, D; Nankai, M | 1 |
| Kalra, PS; Kalra, SP; Pu, S; Xu, B | 1 |
| Biggs, CS; Getting, SJ; Segieth, J; Whitton, PS | 1 |
| Arai, I; Ohno, M; Watanabe, S | 1 |
| Berisha, HI; Pakbaz, H; Said, SI | 1 |
| Acu-na, C; Cudeiro, J; Grieve, KL; Martinez, L; Martinez-Conde, S; Rivadulla, C; Rodriguez, R | 1 |
| Dun, NJ; Wu, SY | 1 |
| Bland-Ward, PA; Moore, PK | 1 |
| Chu, HP; Etgen, AM | 1 |
| Amico, C; Cupello, A; Robello, M | 1 |
| Nabeshima, T; Yamada, K | 2 |
| Johns, RA; Pajewski, TN; Rengasamy, A | 1 |
| Jones, GD; Poston, L | 1 |
| Dawson, TM; Dawson, VL; Facchinetti, F; Hoffman, BE; Newcamp, C; Resink, A; Samdani, AF | 1 |
| Adachi, K; Akaike, A; Fujita, Y; Furutani, I; Honda, Y; Kashii, S; Morizane, C | 1 |
| Ger, LP; Lin, HC; Lo, WC; Tseng, CJ; Tung, CS | 1 |
| Tang, H; Yamamoto, H | 1 |
| Sedlácek, J | 1 |
| Alagarsamy, S; DeWitt, DS; Johnson, KM | 1 |
| Ikarashi, Y; Ishimaru, H; Maruyama, Y; Shiobara, T; Takahashi, A | 1 |
| Cuénod, M; Do, KQ; Grima, G; Mayer, B; Pfeiffer, S | 1 |
| Cox, BA; Johnson, SW | 1 |
| Bashkatova, VG; Mikoian, VD; Narkevich, VB; Raevskiĭ, KS; Vanin, AF; Vitskova, GIu | 1 |
| Cannavò, L; Ginoprelli, T; Ientile, R; Macaione, S; Pedale, S | 1 |
| Kim, HS; Kim, SH; Son, YR | 1 |
| Bartlewski, PM; Beard, AP; Cook, SJ; Honaramooz, A; Rawlings, NC | 1 |
| Nie, H; Qiao, JT; Wang, H; Zhang, RX | 1 |
| Johns, RA; Tichotsky, A; Zuo, Z | 1 |
| Brown, RE; Podhorna, J | 1 |
| Arnolda, LF; Llewellyn-Smith, IJ; McKitrick, DJ; Minson, JB | 1 |
| Gentry, LR; Sticker, LS; Thompson, DL | 1 |
| Leonard, CS; Michaelis, EK; Mitchell, KM | 1 |
| Lefebvre, RA; Timmermans, JP; Van Geldre, LA | 1 |
| Ogonowski, AA; Smith, JB | 1 |
| Ballou, DP; Marsh, EN; Xia, L | 1 |
| Fowler, L; Pearce, B; Watts, J; Whitton, PS | 1 |
| Catterall, WA; Scheuer, T; Sokolov, S | 1 |
| Miguel, TT; Nunes-de-Souza, RL | 1 |
| Cadilhe, DV; Cossenza, M; Coutinho, RN; Paes-de-Carvalho, R | 1 |
| Alexander, GM; Godwin, DW; Kurukulasuriya, NC; Mu, J | 1 |
| Leusink, J; Maarsingh, H; Meurs, H; Zaagsma, J | 1 |
| Fofonova, NV; Saulskaya, NB | 1 |
| Rudhard, Y; Rusakov, DA; Schoepfer, R; Thalhammer, A; Tigaret, CM; Volynski, KE | 1 |
| Brocardo, Pde S; Budni, J; Kaster, MP; Lobato, KR; Rodrigues, AL | 1 |
| Amaral, VC; Carvalho-Netto, EF; Gomes, KS; Nunes-de-Souza, RL | 1 |
| Augusto, O; Camargo, AC; Fox, JW; Guerreiro, JR; Klitzke, CF; Lameu, C; Lebrun, I; Linares, E; Melo, RL; Oliveira, EF; Serrano, SM | 1 |
| Calaza, KC; Gardino, PF; Guimarães-Souza, EM; Maggesissi, RS; Paes-de-Carvalho, R; Silva, RB | 1 |
| Eskridge, LL; Fairbanks, CA; Kitto, KF; Nguyen, HO; Stone, LS; Wade, CL; Wilcox, G | 1 |
| Felipo, V; Llansola, M | 1 |
| Furuse, T; Gondo, Y; Hattori, K; Hirose, R; Kanda, T; Kaneda, H; Kobayashi, K; Kushida, T; Masuya, H; Miura, I; Nakanishi, K; Noda, T; Seno, N; Sezutsu, H; Shibukawa, Y; Toki, S; Wada, Y; Wakana, S; Yamada, I; Yuasa, S | 1 |
| Gorbachevskaia, AI; Saul'skaia, NB | 1 |
| Anrather, J; Chan, J; Coleman, CG; Delagrammatikas, GJ; Iadecola, C; Park, L; Pickel, VM; Wang, G; Zhou, J | 1 |
| Aguiar, DC; Guimarães, FS | 1 |
| Caviedes, A; González, A; Gundelfinger, ED; Kaehne, T; Michea, L; Pancetti, F; Sandoval, R; Smalla, KH; Wyneken, U | 1 |
| Balen, Gde O; Budni, J; Fernandes, SC; Freitas, AE; Moretti, M; Rodrigues, AL | 1 |
| Bettio, LE; Budni, J; Colla, AR; Cunha, MP; Oliveira, Á; Pazini, FL; Rodrigues, AL | 1 |
| Lin, SE; Shen, LJ; Wei, MF; Wu, FL | 1 |
| Corrêa da Silva, JA; da Silva, LM; de Souza, MM; Holzmann, I; Steimbach, VM | 1 |
| Mantovani, AC; Nogueira, CW; Pesarico, AP; Rosa, SG; Stangherlin, EC; Zeni, G | 1 |
| Dehpour, AR; Imran Khan, M; Norouzi-Javidan, A; Ostadhadi, S | 1 |
| Ahangari, M; Akbarian, R; Chamanara, M; Dehpour, AR; Jazaeri, F; Nikoui, V; Norouzi-Javidan, A; Ostadhadi, S; Zolfaghari, S | 1 |
| Almeida, A; Arenillas, JF; Colàs-Campàs, L; Cortijo Garcia, E; de Lera Alfonso, M; Delgado-Esteban, M; Purroy, F; Ramos-Araque, ME; Rodriguez, C; Sanchez Barba, M; Vecino, R | 1 |
| Campello-Costa, P; Cossenza, M; Gladulich, LFH; Paes-de-Carvalho, R; Peixoto-Rodrigues, MC | 1 |
| Hayashi, D; Miyazaki, Y; Okubo, T; Suzuki, T; Takizawa, T; Tanaka, K; Usami, M | 1 |
| Aman, W; Dehpour, AR; Haider, A; Khan, MI; Khan, SN; Mumtaz, F; Naveed, A; Nikoui, V; Ullah, N; Wahab, A; Zaman, H | 1 |
| da Motta, KP; Luchese, C; Martins, CC; Reis, AS; Wilhelm, EA | 1 |
| Akdağlı Ekici, A; Alagöz, A; Ayaz, E; Doğan, G; Karaca, O; Kayır, S; Özcan, O; Yağan, Ö; Yalvaç, M; Zengin, EN; Zengin, M | 1 |
1 trial(s) available for n-methylaspartate and arginine
| Article | Year |
|---|---|
Neuroprotective effects of amantadine for experimental acute carbon monoxide poisoning.
Topics: Amantadine; Animals; Antioxidants; Arginine; Carbon Monoxide; Carbon Monoxide Poisoning; Catalase; D-Aspartic Acid; Formaldehyde; N-Methylaspartate; Neuroprotective Agents; Nitric Oxide; Paraffin; Rats; Receptors, N-Methyl-D-Aspartate; Superoxide Dismutase | 2022 |
153 other study(ies) available for n-methylaspartate and arginine
| Article | Year |
|---|---|
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Evidence that CHP100 neuroblastoma cell death induced by N-methyl-D-aspartate involves L-arginine-nitric oxide pathway activation.
Topics: Amino Acid Oxidoreductases; Arginine; Biotransformation; Brain Neoplasms; Cell Death; Dizocilpine Maleate; Humans; N-Methylaspartate; Neuroblastoma; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Tumor Cells, Cultured | 1992 |
Chronic NO synthase inhibition fails to protect hippocampal neurones against NMDA toxicity.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Hippocampus; N-Methylaspartate; Neurons; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Rats | 1992 |
Involvement of nitric oxide in spinally mediated hyperalgesia in the mouse.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acid Oxidoreductases; Animals; Arginine; Cycloleucine; Hemoglobins; Hydroxylamine; Hydroxylamines; Hyperalgesia; Ibotenic Acid; Injections, Spinal; Kainic Acid; Male; Mice; Mice, Inbred ICR; N-Methylaspartate; Neurotoxins; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; Spinal Cord; Time Factors | 1992 |
Nitric oxide does not mediate the neurotrophic effects of excitatory amino acids in cultured cerebellar granule neurons.
Topics: Animals; Arginine; Cell Survival; Cells, Cultured; Cerebellum; Cyclic GMP; Drug Stability; Kainic Acid; N-Methylaspartate; Nitric Oxide; Nitroarginine; Penicillamine; Rats; Rats, Inbred Strains; S-Nitroso-N-Acetylpenicillamine | 1992 |
Production of endogenous nitric oxide and activation of soluble guanylate cyclase are required for N-methyl-D-aspartate-produced facilitation of the nociceptive tail-flick reflex.
Topics: 2-Amino-5-phosphonovalerate; Animals; Arginine; Enzyme Activation; Guanylate Cyclase; Male; N-Methylaspartate; Nitric Oxide; Pain; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Reflex | 1992 |
Structural determinants of barium permeation and rectification in non-NMDA glutamate receptor channels.
Topics: Amino Acid Sequence; Animals; Arginine; Barium; Glutamates; Glutamic Acid; Glutamine; Molecular Sequence Data; Mutation; N-Methylaspartate; Permeability; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Xenopus | 1992 |
Glutamate receptor agonists stimulate nitric oxide synthase in primary cultures of cerebellar granule cells.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Calcium; Cells, Cultured; Cerebellum; Citrulline; Cyclic GMP; Glutamates; Glutamic Acid; Granulocytes; Kainic Acid; N-Methylaspartate; Nitric Oxide Synthase; Quisqualic Acid; Receptors, Glutamate; Receptors, Neurotransmitter | 1992 |
In vitro interaction between cerebellar astrocytes and granule cells: a putative role for nitric oxide.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Astrocytes; Calcimycin; Cell Communication; Cells, Cultured; Cerebellum; Citrulline; Cyclic GMP; Kinetics; N-Methylaspartate; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; Rats | 1992 |
Evidence that pharmacological manipulations of central L-arginine-NO pathway influence blood pressure and heart rate in rats.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Blood Pressure; Brain; Endotoxins; Heart Rate; Injections, Intraventricular; Lipopolysaccharides; Male; N-Methylaspartate; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate | 1992 |
Actions of arginine polyamine on voltage and ligand-activated whole cell currents recorded from cultured neurones.
Topics: Animals; Arginine; Calcium; Calcium Channels; Cells, Cultured; Electrophysiology; gamma-Aminobutyric Acid; Ganglia, Spinal; Ion Channels; N-Methylaspartate; Neurons; omega-Conotoxins; Peptides, Cyclic; Polyamines; Potassium; Rats | 1992 |
Evidence for nitric oxide synthase inhibitor-sensitive and insensitive hippocampal synaptic potentiation.
Topics: 2-Amino-5-phosphonovalerate; Amino Acid Oxidoreductases; Animals; Arginine; Conditioning, Psychological; Evoked Potentials; Hippocampus; In Vitro Techniques; Male; N-Methylaspartate; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Rats; Rats, Inbred F344; Synapses | 1992 |
Effect of NO synthase inhibition on NMDA- and ischaemia-induced hippocampal lesions.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acid Oxidoreductases; Animals; Arginine; Brain Ischemia; Dose-Response Relationship, Drug; Hippocampus; Ibotenic Acid; Male; N-Methylaspartate; Neurons; Neurotoxins; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Pyramidal Tracts; Rats; Rats, Wistar | 1992 |
NMDA-induced release of nitric oxide potentiates aspartate overflow from cerebellar slices.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Arginine; Aspartic Acid; Cerebellum; Ibotenic Acid; In Vitro Techniques; Kainic Acid; Magnesium; N-Methylaspartate; Nitric Oxide; omega-N-Methylarginine; Quisqualic Acid; Rats; Rats, Wistar | 1992 |
Inhibition of long-term potentiation by NMDA-mediated nitric oxide release.
Topics: Animals; Arginine; Electrophysiology; Hemoglobins; Hippocampus; In Vitro Techniques; N-Methylaspartate; Nitric Oxide; Nitroprusside; omega-N-Methylarginine; Rats; Time Factors | 1992 |
Nitric oxide inhibitors attenuate N-methyl-D-aspartate excitotoxicity in rat hippocampal slices.
Topics: Animals; Arginine; Calcium; Hemoglobins; Hippocampus; In Vitro Techniques; N-Methylaspartate; Nerve Degeneration; Nitric Oxide; Nitroarginine; omega-N-Methylarginine; Rats; Synapses | 1992 |
NMDA receptor activation in rat hippocampus induces cyclic GMP formation through the L-arginine-nitric oxide pathway.
Topics: Animals; Arginine; Cyclic GMP; Hippocampus; In Vitro Techniques; Kinetics; N-Methylaspartate; Nitric Oxide; Nitroarginine; omega-N-Methylarginine; Rats; Receptors, N-Methyl-D-Aspartate | 1991 |
Nitric oxide mediates glutamate neurotoxicity in primary cortical cultures.
Topics: Animals; Arginine; Cell Survival; Cells, Cultured; Citrulline; Cyclic GMP; Dizocilpine Maleate; Fetus; Glutamates; Hemoglobins; Hippocampus; Kinetics; N-Methylaspartate; Neurons; Neurotoxins; Nitric Oxide; Rats; Receptors, N-Methyl-D-Aspartate; Superoxide Dismutase | 1991 |
Absence of implication of L-arginine/nitric oxide pathway on neuronal cell injury induced by L-glutamate or hypoxia.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Arginine; Brain; Cell Hypoxia; Cells, Cultured; Cyclic GMP; Dizocilpine Maleate; Fetus; Glutamates; Glutamic Acid; Kainic Acid; Kinetics; N-Methylaspartate; Neuroglia; Neurons; Nitric Oxide; Nitroarginine; Nitroprusside; omega-N-Methylarginine; Quisqualic Acid; Rats | 1991 |
Nitric oxide synthesis in the CNS endothelium and macrophages differs in its sensitivity to inhibition by arginine analogues.
Topics: Animals; Arginine; Central Nervous System; Cyclic GMP; Endothelium; In Vitro Techniques; Macrophages; Mice; N-Methylaspartate; Nitric Oxide; Nitroarginine; omega-N-Methylarginine; Rats | 1991 |
Evidence that L-arginine possesses proconvulsant effects mediated through nitric oxide.
Topics: Animals; Arginine; Behavior, Animal; Convulsants; Electrocardiography; Exploratory Behavior; Injections, Intraventricular; Male; Motor Activity; N-Methylaspartate; Nitric Oxide; Nitroarginine; Rats; Rats, Inbred Strains; Stereotaxic Techniques | 1991 |
Role of nitric oxide in the genesis of excitatory amino acid-induced seizures from the deep prepiriform cortex.
Topics: Animals; Arginine; Electric Stimulation; Electroencephalography; Kainic Acid; Male; Methylene Blue; N-Methylaspartate; Nitric Oxide; omega-N-Methylarginine; Rats; Rats, Inbred Strains; Seizures; Temporal Lobe | 1991 |
Nanomolar N(G)-nitroarginine inhibits NMDA-induced cyclic GMP formation in rat cerebellum.
Topics: Animals; Arginine; Cerebellum; Cyclic GMP; In Vitro Techniques; N-Methylaspartate; Nitroarginine; Rats | 1990 |
Substitution of a lysyl residue for arginine 386 of Escherichia coli aspartate aminotransferase.
Topics: Amino Acid Sequence; Arginine; Aspartate Aminotransferases; Aspartic Acid; Binding Sites; Catalysis; Escherichia coli; Kinetics; Lysine; Mutation; N-Methylaspartate; Substrate Specificity | 1989 |
Nitric oxide mediates glutamate-linked enhancement of cGMP levels in the cerebellum.
Topics: Animals; Arginine; Aspartic Acid; Cerebellum; Citrulline; Cyclic GMP; Glutamates; Glutamic Acid; Hemoglobins; In Vitro Techniques; Kainic Acid; Kinetics; N-Methylaspartate; Nitric Oxide; omega-N-Methylarginine; Oxadiazoles; Quisqualic Acid; Rats | 1989 |
Intrauterine hypoxia-ischemia increases N-methyl-D-aspartate-induced cGMP formation and glutamate accumulation in cultured rat cerebellar granule cells.
Topics: Animals; Arginine; Brain Ischemia; Cells, Cultured; Cerebellar Diseases; Chronic Disease; Cyclic GMP; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Fetal Hypoxia; Gestational Age; Glutamic Acid; Hypoxia, Brain; Kainic Acid; N-Methylaspartate; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley | 1995 |
NMDA-dependent prostaglandin E2 release by human cultured astroglial cells is driven by nitric oxide.
Topics: Arachidonic Acid; Arginine; Astrocytes; Astrocytoma; Cell Line; Cyclic GMP; Dinoprostone; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Kinetics; N-Methylaspartate; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Nitroprusside; Oxyhemoglobins; Receptors, N-Methyl-D-Aspartate; Tumor Cells, Cultured | 1995 |
The role of P-type calcium channels in the depolarization-induced activation of nitric oxide synthase in frontal cortex.
Topics: Amiloride; Amino Acid Oxidoreductases; Analysis of Variance; Animals; Arginine; Calcium Channel Blockers; Calcium Channels; Carrier Proteins; Citrulline; Enzyme Activation; Frontal Lobe; In Vitro Techniques; Male; N-Methylaspartate; Nitric Oxide Synthase; Nitroarginine; omega-Conotoxins; Peptides; Pipecolic Acids; Polyamines; Potassium; Rats; Rats, Sprague-Dawley; Sodium-Calcium Exchanger | 1994 |
N-methyl-D-aspartate-induced nitric oxide release: an in vivo microdialysis study.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Dose-Response Relationship, Drug; Male; Microdialysis; N-Methylaspartate; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Rats; Rats, Wistar | 1993 |
Role of NO production in NMDA receptor-mediated neurotransmitter release in cerebral cortex.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cerebral Cortex; Glutamates; Glutamic Acid; Guinea Pigs; In Vitro Techniques; Indazoles; Male; N-Methylaspartate; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Norepinephrine; omega-N-Methylarginine; Potassium Chloride; Receptors, N-Methyl-D-Aspartate; Synaptosomes | 1994 |
Nitric oxide, superoxide and peroxynitrite: putative mediators of NMDA-induced cell death in cerebellar granule cells.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Catalase; Cell Death; Cells, Cultured; Cerebellum; Cyclic GMP; Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Mice; Molsidomine; N-Methylaspartate; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Receptors, N-Methyl-D-Aspartate; Superoxide Dismutase; Superoxides; Xanthine Oxidase | 1993 |
Lack of involvement of nitric oxide in NMDA-induced neuronal cell death in cortical culture.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cell Death; Cells, Cultured; Cerebral Cortex; Cyclic GMP; Models, Neurological; N-Methylaspartate; Neurons; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Rats | 1993 |
Nitric oxide in retina: relation to excitatory amino acids and excitotoxicity.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cell Death; Chick Embryo; Cyclic GMP; gamma-Aminobutyric Acid; Glutamates; L-Lactate Dehydrogenase; N-Methylaspartate; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Retina | 1994 |
Glutamate receptors induce a burst of superoxide via activation of nitric oxide synthase in arginine-depleted neurons.
Topics: Amino Acid Oxidoreductases; Animals; Arginase; Arginine; Brain; Cell Death; Cells, Cultured; Cyclic GMP; Electron Spin Resonance Spectroscopy; Enzyme Activation; Male; Mice; N-Methylaspartate; Neurons; Nitric Oxide Synthase; Receptors, Glutamate; Superoxides | 1994 |
Effects of nitric oxide synthase inhibitors on N-methyl-D-aspartate-induced phase delay of circadian rhythm of neuronal activity in the rat suprachiasmatic nucleus in vitro.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acid Oxidoreductases; Animals; Arginine; Circadian Rhythm; In Vitro Techniques; N-Methylaspartate; Neurons; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Rats; Rats, Wistar; Stereoisomerism; Suprachiasmatic Nucleus | 1994 |
The NO-cGMP pathway in neonatal rat dorsal horn.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acid Oxidoreductases; Animals; Animals, Newborn; Arginine; Biomarkers; Cyclic GMP; Female; Glutathione; Male; N-Methylaspartate; NADPH Dehydrogenase; Nerve Tissue Proteins; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Nitroprusside; Nitroso Compounds; Pain; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; S-Nitrosoglutathione; Second Messenger Systems; Signal Transduction; Spinal Cord | 1994 |
Nitric oxide synthesized by gonadotropin-releasing hormone neurons is a mediator of N-methyl-D-aspartate (NMDA)-induced GnRH secretion.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Blotting, Northern; Calcium; Cell Line; DNA; Gonadotropin-Releasing Hormone; Hypothalamus; N-Methylaspartate; Neurons; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Nitroprusside; RNA, Messenger | 1994 |
Release of the nitric oxide precursor, arginine, from the thalamus upon sensory afferent stimulation, and its effect on thalamic neurons in vivo.
Topics: Afferent Pathways; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Arginine; Glutamic Acid; Male; N-Methylaspartate; Neurons; Neurons, Afferent; NG-Nitroarginine Methyl Ester; Nitric Oxide; Potassium; Rats; Rats, Wistar; Synaptic Transmission; Thalamus; Vibrissae | 1994 |
Acetaminophen blocks spinal hyperalgesia induced by NMDA and substance P.
Topics: Acetaminophen; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Arginine; Behavior, Animal; Dose-Response Relationship, Drug; Hyperalgesia; Injections, Spinal; N-Methylaspartate; Nociceptors; Rats; Rats, Sprague-Dawley; Spinal Cord Diseases; Substance P | 1994 |
Spinal mediators of hyperalgesia.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Arachidonic Acid; Arginine; Calcium; Cycloleucine; Disease Models, Animal; Excitatory Amino Acids; Hot Temperature; Hyperalgesia; Male; N-Methylaspartate; Neuronal Plasticity; Neurons, Afferent; Neurotoxins; NG-Nitroarginine Methyl Ester; Nitric Oxide; Physical Stimulation; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Stress, Mechanical | 1994 |
Polyamines inhibit nitric oxide synthase in rat cerebellum.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cells, Cultured; Cerebellum; Citrulline; Cytosol; Eflornithine; Kinetics; N-Methylaspartate; Neurons; Nitric Oxide Synthase; omega-N-Methylarginine; Polyamines; Putrescine; Rats; Spermidine; Spermine; Tritium | 1994 |
Induction in the rat hippocampus of long-term potentiation (LTP) and long-term depression (LTD) in the presence of a nitric oxide synthase inhibitor.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cyclic GMP; Electric Stimulation; Evoked Potentials; Hippocampus; In Vitro Techniques; Long-Term Potentiation; N-Methylaspartate; Neuronal Plasticity; Neurons; Nitric Oxide Synthase; Nitroarginine; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Time Factors | 1994 |
Resetting the biological clock: mediation of nocturnal circadian shifts by glutamate and NO.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Biological Clocks; Circadian Rhythm; Glutamic Acid; In Vitro Techniques; Light; N-Methylaspartate; Neurons, Afferent; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Receptors, N-Methyl-D-Aspartate; Retina; Signal Transduction; Suprachiasmatic Nucleus | 1994 |
Nitric oxide synthase inhibitors prevent N-methyl-D-aspartic acid-induced penile erection and yawning in male rats.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Dose-Response Relationship, Drug; Free Radical Scavengers; Injections; Male; Methemoglobin; Methylene Blue; N-Methylaspartate; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Paraventricular Hypothalamic Nucleus; Penile Erection; Rats; Rats, Sprague-Dawley; Yawning | 1994 |
NMDA-dependent nitric oxide release in the hippocampus in vivo: interactions with noradrenaline.
Topics: Adrenergic alpha-1 Receptor Antagonists; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acid Oxidoreductases; Animals; Arginine; Benzylamines; Hippocampus; Male; Microdialysis; N-Methylaspartate; Neurotransmitter Uptake Inhibitors; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Norepinephrine; Rats; Rats, Wistar | 1994 |
The role of nitric oxide in the transformation of visual information within the dorsal lateral geniculate nucleus of the cat.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cats; Cyclic GMP; Geniculate Bodies; Iontophoresis; N-Methylaspartate; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Receptors, N-Methyl-D-Aspartate; Vision, Ocular | 1994 |
Nitric oxide does not mediate acute glutamate neurotoxicity, nor is it neuroprotective, in rat brain slices.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cerebellum; Excitatory Amino Acids; Glutamic Acid; Hippocampus; In Vitro Techniques; N-Methylaspartate; Nerve Degeneration; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Rats; Rats, Wistar | 1994 |
The role of free radicals in NMDA-dependent neurotoxicity.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Calcium; Cells, Cultured; Cerebellar Cortex; Cyclic GMP; Electron Spin Resonance Spectroscopy; Enzyme Activation; Epilepsy; Feedback; Free Radicals; Glutamic Acid; Guanylate Cyclase; Kindling, Neurologic; Mice; Molsidomine; N-Methylaspartate; Nerve Tissue Proteins; Neurons; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Rats; Receptors, N-Methyl-D-Aspartate | 1994 |
Excitotoxic action of NMDA agonists on nigrostriatal dopaminergic neurons: modulation by inhibition of nitric oxide synthesis.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cerebellum; Corpus Striatum; Dose-Response Relationship, Drug; Immunohistochemistry; Male; N-Methylaspartate; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Quinolinic Acid; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Substantia Nigra | 1995 |
Delayed antagonism of calpain reduces excitotoxicity in cultured neurons.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Calpain; Cell Survival; Cells, Cultured; Cerebellum; Dipeptides; Enzyme Activation; Glutamic Acid; Hippocampus; Kainic Acid; Leucine; N-Methylaspartate; Neurons; Neuroprotective Agents; Nitric Oxide Synthase; Nitroarginine; Rats; Receptors, N-Methyl-D-Aspartate; Spectrin; Time Factors | 1995 |
Adenosine modulates N-methyl-D-aspartate-stimulated hippocampal nitric oxide production in vivo.
Topics: 2-Chloroadenosine; Adenosine; Amino Acid Oxidoreductases; Animals; Arginine; Carbon Radioisotopes; Citrulline; Excitatory Amino Acid Antagonists; Hippocampus; Male; N-Methylaspartate; Neuroprotective Agents; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Norbornanes; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Xanthines | 1995 |
Effects of nitric oxide availability on responses of spinal wide dynamic range neurons to excitatory amino acids.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acid Oxidoreductases; Analysis of Variance; Animals; Arginine; Iontophoresis; Kainic Acid; Male; N-Methylaspartate; Neurons; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Ornithine; Penicillamine; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; S-Nitroso-N-Acetylpenicillamine; Spinal Canal | 1995 |
Influence of nitric oxide synthase inhibition on the development of rapid tolerance to ethanol.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Brain; Cycloserine; Drug Tolerance; Ethanol; Male; N-Methylaspartate; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Postural Balance; Rats; Rats, Sprague-Dawley | 1995 |
Alteration in the glial cell metabolism of glutamate by kainate and N-methyl-D-aspartate.
Topics: Animals; Arginine; Brain; Brain Chemistry; Glutamate-Ammonia Ligase; Glutamate-Cysteine Ligase; Glutamic Acid; In Vitro Techniques; Kainic Acid; N-Methylaspartate; Neuroglia; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Phosphopyruvate Hydratase; Rats; Rats, Wistar | 1995 |
A dual role for nitric oxide in NMDA-mediated toxicity in vivo.
Topics: Animals; Arginine; Autoradiography; Cerebrovascular Circulation; Corpus Striatum; Male; N-Methylaspartate; Neurotoxins; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Wistar | 1995 |
Involvement of nitric oxide in dopaminergic transmission in rat striatum: an in vivo electrochemical study.
Topics: Animals; Arginine; Corpus Striatum; Dopamine; Electrochemistry; Male; N-Methylaspartate; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; Rats; Rats, Sprague-Dawley; Stereoisomerism; Synaptic Transmission | 1995 |
In vivo production of nitric oxide correlates with NMDA-induced cerebral hyperemia in newborn sheep.
Topics: 2-Chloroadenosine; Animals; Animals, Newborn; Arginine; Blood Volume; Cerebrovascular Circulation; Citrulline; Drug Combinations; Microdialysis; N-Methylaspartate; NG-Nitroarginine Methyl Ester; Nitric Oxide; Parietal Lobe; Sheep | 1995 |
Reduction of striatal N-methyl-D-aspartate toxicity by inhibition of nitric oxide synthase.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Corpus Striatum; Glutamate-Ammonia Ligase; Kainic Acid; N-Methylaspartate; Nitric Oxide Synthase; Nitroarginine; Phosphopyruvate Hydratase; Rats | 1993 |
L-NAME blocks responses to NMDA, substance P and noxious cutaneous stimuli in cat dorsal horn.
Topics: Animals; Appetite Depressants; Arginine; Cats; Electrodes; Electrophysiology; Extracellular Space; Iontophoresis; N-Methylaspartate; NG-Nitroarginine Methyl Ester; Physical Stimulation; Quisqualic Acid; Skin; Skin Physiological Phenomena; Spinal Cord; Substance P | 1993 |
Further studies concerning the role of nitric oxide in LTP induction and maintenance.
Topics: 2-Amino-5-phosphonovalerate; Amino Acid Oxidoreductases; Animals; Arginine; Electric Stimulation; Evoked Potentials; Free Radical Scavengers; Hemoglobins; Hippocampus; In Vitro Techniques; Male; N-Methylaspartate; Neuronal Plasticity; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Potassium Channels; Rats; Rats, Sprague-Dawley; Synapses; Tetraethylammonium Compounds | 1993 |
Glutamate receptor-induced cyclic GMP formation in primary cultures of mesencephalic neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acid Oxidoreductases; Animals; Arginine; Carbachol; Cells, Cultured; Cyclic GMP; Fetus; Glutamates; Glutamic Acid; Ibotenic Acid; Kainic Acid; Kinetics; Mesencephalon; Mice; N-Methylaspartate; Neurons; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Phorbol 12,13-Dibutyrate; Quinoxalines; Receptors, Glutamate | 1993 |
Mechanisms involved in the neuroprotective activity of a nitric oxide synthase inhibitor during focal cerebral ischemia.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Aspartic Acid; Blood Pressure; Corpus Striatum; Glutamates; Glutamic Acid; Ischemic Attack, Transient; Kinetics; Male; N-Methylaspartate; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Potassium; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 1993 |
Nitric oxide inhibitors facilitate the induction of hippocampal long-term potentiation by modulating NMDA responses.
Topics: 2-Amino-5-phosphonovalerate; Amino Acid Oxidoreductases; Animals; Arginine; Culture Techniques; Hippocampus; Long-Term Potentiation; Male; Membrane Potentials; N-Methylaspartate; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Rats; Receptors, N-Methyl-D-Aspartate | 1993 |
Glutamate induces the production of reactive oxygen species in cultured forebrain neurons following NMDA receptor activation.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Arginine; Calcium; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Cells, Cultured; Cerebral Cortex; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Fetus; Glutamic Acid; Indomethacin; Kainic Acid; Kinetics; Masoprocol; N-Methylaspartate; Neurons; Nitroarginine; Prosencephalon; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Spectrometry, Fluorescence; Time Factors | 1995 |
No evidence for contribution of nitric oxide to spinal reflex activity in the rat spinal cord in vitro.
Topics: 2-Amino-5-phosphonovalerate; Animals; Arginine; Electric Stimulation; Hyperalgesia; In Vitro Techniques; N-Methylaspartate; Nerve Fibers; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Reflex; Spinal Cord; Spinal Nerve Roots | 1995 |
Sodium nitroprusside modulates NMDA response in the rat supraoptic neurons in vitro.
Topics: Animals; Arginine; Cyclic GMP; Ferricyanides; In Vitro Techniques; Isosorbide Dinitrate; Kainic Acid; Male; Membrane Potentials; N-Methylaspartate; Neurons; Nitroarginine; Nitroprusside; Protein Kinases; Quisqualic Acid; Rats; Rats, Wistar; Supraoptic Nucleus | 1994 |
N-methyl-D-aspartate-induced excessive formation of nitric oxide in CHP100 neuroblastoma cells produces death of BMEL melanoma cells in co-culture.
Topics: Arginine; Cell Death; Dizocilpine Maleate; Histocytochemistry; Humans; Melanoma, Experimental; N-Methylaspartate; NADPH Dehydrogenase; Neuroblastoma; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroprusside; omega-N-Methylarginine; Tumor Cells, Cultured | 1994 |
Nitric oxide is a central mediator of penile erection.
Topics: Animals; Apomorphine; Arginine; Dose-Response Relationship, Drug; Injections; Injections, Intraventricular; Male; Methylene Blue; N-Methylaspartate; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroglycerin; Oxytocin; Paraventricular Hypothalamic Nucleus; Penile Erection; Rats; Rats, Sprague-Dawley | 1994 |
N-methyl-D-aspartate (NMDA) stimulates release of alpha-MSH from the rat hypothalamus through release of nitric oxide.
Topics: 2-Amino-5-phosphonovalerate; alpha-MSH; Animals; Arginine; Hypothalamus; Ketamine; Male; N-Methylaspartate; NG-Nitroarginine Methyl Ester; Nitric Oxide; Potassium; Rats; Rats, Wistar | 1994 |
Endogenous nitric oxide inhibits NMDA- and kainate- responses by a negative feedback system in rat hippocampal neurons.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Arginine; Calcium; Cells, Cultured; Cyclic GMP; Feedback; Glutamates; Glutamic Acid; Hemoglobins; Hippocampus; Kainic Acid; N-Methylaspartate; Neurons; Nitric Oxide; Nitroarginine; Osmolar Concentration; Rats; Rats, Wistar; Receptors, Amino Acid | 1993 |
Characterization of the role of spinal N-methyl-D-aspartate receptors in thermal nociception in the rat.
Topics: 2-Amino-5-phosphonovalerate; Animals; Arginine; Behavior, Animal; Cold Temperature; Hot Temperature; Male; Methysergide; N-Methylaspartate; Nitroarginine; Nociceptors; Pain; Phentolamine; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Reflex; Spinal Cord | 1993 |
Subcutaneous formalin produces centrifugal hyperalgesia at a non-injected site via the NMDA-nitric oxide cascade.
Topics: 2-Amino-5-phosphonovalerate; Animals; Arginine; Cordotomy; Formaldehyde; Hot Temperature; Hyperalgesia; Injections, Spinal; Injections, Subcutaneous; N-Methylaspartate; NG-Nitroarginine Methyl Ester; Nitric Oxide; Pain Measurement; Rats; Rats, Sprague-Dawley; Spinal Cord | 1994 |
N-Methyl-D-aspartate receptor-mediated signaling in the supraoptic nucleus involves activation of a nitric oxide-dependent pathway.
Topics: Animals; Arginine; Calcimycin; Chlorisondamine; Cyclic GMP; Heart Rate; Male; Microinjections; N-Methylaspartate; NG-Nitroarginine Methyl Ester; Nitric Oxide; Piperazines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Supraoptic Nucleus | 1994 |
Effects of L- and D-enantiomers of N omega-nitro-arginine on NMDA-evoked striatal dopamine overflow.
Topics: Animals; Arginine; Corpus Striatum; Dopamine; Extracellular Space; Male; Microdialysis; N-Methylaspartate; Nitroarginine; Osmolar Concentration; Rats; Rats, Wistar | 1994 |
Non-classical glutamate receptors, blocked by both NMDA and non-NMDA antagonists, stimulate nitric oxide production in neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Arginine; Cells, Cultured; Corpus Striatum; Cyclic GMP; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Female; Mice; N-Methylaspartate; Neurons; Nitric Oxide; Nitroarginine; omega-N-Methylarginine; Pregnancy; Quinoxalines; Quisqualic Acid; Receptors, Glutamate | 1993 |
Glutamate and theta-rhythm stimulation selectively enhance NMDA component of EPSC in CA1 neurons of young rats.
Topics: Aging; Animals; Arginine; Evoked Potentials; Glutamates; Glutamic Acid; Hemoglobins; In Vitro Techniques; N-Methylaspartate; Neuronal Plasticity; Neurons; Nitroarginine; Norepinephrine; Rats; Rats, Wistar; Synapses; Synaptic Transmission; Theta Rhythm | 1993 |
NMDA evokes an L-NAME sensitive spinal release of glutamate and citrulline.
Topics: Animals; Arginine; Citrulline; Dialysis; Dizocilpine Maleate; Glutamates; Glutamic Acid; Injections, Spinal; Male; N-Methylaspartate; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Sprague-Dawley; Spinal Cord | 1993 |
NMDA-evoked adenosine release from rat cortex does not require the intermediate formation of nitric oxide.
Topics: Adenosine; Animals; Arginine; Cerebral Cortex; In Vitro Techniques; Male; N-Methylaspartate; Nitric Oxide; Nitroarginine; Nitroprusside; Rats; Rats, Sprague-Dawley | 1993 |
Spinal nitric oxide synthesis inhibition blocks NMDA-induced thermal hyperalgesia and produces antinociception in the formalin test in rats.
Topics: Analgesics; Animals; Arginine; Behavior, Animal; Formaldehyde; Hot Temperature; Injections, Spinal; Male; N-Methylaspartate; NG-Nitroarginine Methyl Ester; Nitric Oxide; omega-N-Methylarginine; Pain; Pain Measurement; Rats; Rats, Sprague-Dawley; Spinal Cord | 1993 |
Evidence that nitric oxide may mediate the ovarian steroid-induced luteinizing hormone surge: involvement of excitatory amino acids.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Arginine; Estradiol; Female; Hypothalamus, Middle; Luteinizing Hormone; N-Methylaspartate; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroprusside; Ovariectomy; Pituitary Gland; Preoptic Area; Progesterone; Rats | 1993 |
Inhibition of nitric oxide formation does not protect murine cortical cell cultures from N-methyl-D-aspartate neurotoxicity.
Topics: Animals; Arginine; Cell Death; Cells, Cultured; Cerebral Cortex; Cyclic GMP; Dextrorphan; Mice; N-Methylaspartate; Nitric Oxide; Nitroarginine; omega-N-Methylarginine; Rats | 1993 |
L-arginine potentiates excitatory amino acid-induced seizures elicited in the deep prepiriform cortex.
Topics: Animals; Arginine; Brain; Drug Synergism; Electroencephalography; Kainic Acid; Male; Microinjections; N-Methylaspartate; Nitric Oxide; Nitroprusside; Rats; Rats, Wistar; Seizures; Stereoisomerism | 1993 |
Delayed production of nitric oxide contributes to NMDA-mediated neuronal damage.
Topics: Animals; Arginine; Cell Death; Cells, Cultured; Cerebral Cortex; L-Lactate Dehydrogenase; Mice; N-Methylaspartate; Neurons; Nitric Oxide; Nitroarginine | 1993 |
Experimental neuronal injury in the newborn lamb: a comparison of N-methyl-D-aspartic acid receptor blockade and nitric oxide synthesis inhibition on lesion size and cerebral hyperemia.
Topics: Animals; Animals, Newborn; Arginine; Brain Diseases; Cattle; Disease Models, Animal; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Hemodynamics; Hyperemia; N-Methylaspartate; Neuroprotective Agents; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Receptors, N-Methyl-D-Aspartate; Sheep | 1995 |
Lack of correlation between glutamate-induced depletion of ATP and neuronal death in primary cultures of cerebellum.
Topics: Adenosine Triphosphate; Animals; Arginine; Cell Death; Cells, Cultured; Cerebellum; Coloring Agents; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; N-Methylaspartate; Neurons; Nitric Oxide Synthase; Nitroarginine; Rats; Rats, Wistar; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate | 1995 |
Striatal NMDA receptor subtypes: the pharmacology of N-methyl-D-aspartate-evoked dopamine, gamma-aminobutyric acid, acetylcholine and spermidine release.
Topics: Animals; Arginine; Corpus Striatum; Dantrolene; Excitatory Amino Acid Antagonists; Glycine Agents; In Vitro Techniques; Muscle Relaxants, Central; N-Methylaspartate; Neurotransmitter Agents; Nitroarginine; Rats; Receptors, N-Methyl-D-Aspartate; Spermidine; Tetrodotoxin | 1995 |
Evidence that gonadal steroids modulate nitric oxide efflux in the medial preoptic area: effects of N-methyl-D-aspartate and correlation with luteinizing hormone secretion.
Topics: 2-Amino-5-phosphonovalerate; Animals; Arginine; Cyclic GMP; Enzyme Inhibitors; Female; Luteinizing Hormone; Male; N-Methylaspartate; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Preoptic Area; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 1996 |
Nitric oxide regulates excitatory amino acid release in a biphasic manner in freely moving rats.
Topics: Animals; Arginine; Aspartic Acid; Enzyme Inhibitors; Excitatory Amino Acids; Glutamic Acid; Hippocampus; Male; Microdialysis; Motor Activity; N-Methylaspartate; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Penicillamine; Rats; Rats, Wistar; S-Nitroso-N-Acetylpenicillamine; Vasodilator Agents | 1995 |
N-methyl-D-aspartate stimulates dopamine release through nitric oxide formation in the nucleus accumbens of rats.
Topics: Animals; Arginine; Dopamine; Dose-Response Relationship, Drug; Male; N-Methylaspartate; Nitric Oxide; Nucleus Accumbens; Rats; Rats, Wistar | 1995 |
Excitotoxicity in the lung: N-methyl-D-aspartate-induced, nitric oxide-dependent, pulmonary edema is attenuated by vasoactive intestinal peptide and by inhibitors of poly(ADP-ribose) polymerase.
Topics: Animals; Arginine; Benzamides; Cyclic GMP; Enzyme Inhibitors; In Vitro Techniques; Lung; Lung Injury; Magnesium; Male; Models, Biological; N-Methylaspartate; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Perfusion; Poly(ADP-ribose) Polymerase Inhibitors; Pulmonary Edema; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Vasoactive Intestinal Peptide | 1996 |
Further observations on the role of nitric oxide in the feline lateral geniculate nucleus.
Topics: Afferent Pathways; Animals; Arginine; Cats; Electric Stimulation; Electroencephalography; Enzyme Inhibitors; gamma-Aminobutyric Acid; Geniculate Bodies; Iontophoresis; Models, Neurological; N-Methylaspartate; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Nitroprusside; omega-N-Methylarginine; Paralysis; Penicillamine; Photic Stimulation; S-Nitroso-N-Acetylpenicillamine; Synapses; Time Factors; Visual Fields; Visual Perception | 1996 |
Calcium-activated release of nitric oxide potentiates excitatory synaptic potentials in immature rat sympathetic preganglionic neurons.
Topics: Adrenergic Fibers; Animals; Arginine; Autonomic Fibers, Preganglionic; Calcium; Calcium Channels; Chelating Agents; Egtazic Acid; Enzyme Inhibitors; Hemoglobins; In Vitro Techniques; Ion Channel Gating; Membrane Potentials; N-Methylaspartate; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Spinal Cord; Synapses | 1995 |
7-nitroindazole: an inhibitor of nitric oxide synthase.
Topics: Analgesics; Animals; Aorta; Arginine; Carbachol; Cattle; Cerebellum; Endothelium, Vascular; Enzyme Inhibitors; Female; Indazoles; Isoenzymes; Lung; Male; Mice; Molecular Structure; N-Methylaspartate; Neurons; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitro Compounds; Rabbits; Radioisotope Dilution Technique; Rats; Sensitivity and Specificity; Structure-Activity Relationship; Tritium | 1996 |
Effects of nitric oxide on stimulated release of norepinephrine from female rat hypothalamic slices.
Topics: Adrenergic Uptake Inhibitors; Animals; Arginine; Electric Stimulation; Enzyme Inhibitors; Estrogens; Female; Hypothalamus; In Vitro Techniques; N-Methylaspartate; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; Norepinephrine; Ovariectomy; Preoptic Area; Progesterone; Rats; Rats, Sprague-Dawley | 1996 |
A dual mechanism for impairment of GABAA receptor activity by NMDA receptor activation in rat cerebellum granule cells.
Topics: Animals; Arginine; Calcineurin; Calcium; Calmodulin-Binding Proteins; Cells, Cultured; Cerebellum; Cytoplasmic Granules; Electrophysiology; Enzyme Inhibitors; N-Methylaspartate; Nitric Oxide Synthase; Phosphoprotein Phosphatases; Rats; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate | 1997 |
Simultaneous measurement of nitrite and nitrate levels as indices of nitric oxide release in the cerebellum of conscious rats.
Topics: Animals; Arginine; Calcium; Cerebellum; Enzyme Inhibitors; Extracellular Space; Glutamic Acid; Male; N-Methylaspartate; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Rats; Rats, Wistar | 1997 |
Inhalational anesthetic effects on rat cerebellar nitric oxide and cyclic guanosine monophosphate production.
Topics: Anesthetics, Inhalation; Animals; Arginine; Cerebellum; Citrulline; Cyclic GMP; Drug Interactions; Excitatory Amino Acid Agonists; Halothane; Isoflurane; N-Methylaspartate; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Stimulation, Chemical; Tritium | 1997 |
The role of endogenous nitric oxide synthesis in contractility of term or preterm human myometrium.
Topics: Arginine; Female; Humans; Muscle Contraction; Myometrium; N-Methylaspartate; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Obstetric Labor, Premature; Pregnancy | 1997 |
Differential susceptibility to neurotoxicity mediated by neurotrophins and neuronal nitric oxide synthase.
Topics: Animals; Arginine; Brain-Derived Neurotrophic Factor; Cell Survival; Cells, Cultured; Cerebral Cortex; Coculture Techniques; Embryo, Mammalian; Fetus; Gene Expression Regulation, Enzymologic; Glial Cell Line-Derived Neurotrophic Factor; Kinetics; Mice; Mice, Inbred C57BL; N-Methylaspartate; Nerve Growth Factors; Nerve Tissue Proteins; Neuroglia; Neurons; Neurotoxins; Neurotrophin 3; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitroprusside; Peptides; Rats; Rats, Sprague-Dawley | 1997 |
N(omega)-nitro-L-arginine methyl ester protects retinal neurons against N-methyl-D-aspartate-induced neurotoxicity in vivo.
Topics: Animals; Arginine; Cell Count; Dizocilpine Maleate; Drug Interactions; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Male; N-Methylaspartate; Neurons; Neuroprotective Agents; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Retina; Stereoisomerism; Vitreous Body | 1997 |
Two pathways of nitric oxide production through glutamate receptors in the rat cerebellum in vivo.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Arginine; Calcium; Cerebellum; Cycloleucine; Cytochrome P-450 Enzyme Inhibitors; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Extracellular Space; Male; N-Methylaspartate; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Rats; Rats, Wistar; Receptors, Glutamate | 1997 |
Actions of compounds manipulating the nitric oxide system in the cat primary visual cortex.
Topics: Acetylcholine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Arginine; Cats; Cyclic GMP; Electrophysiology; Enzyme Inhibitors; Excitatory Amino Acids; Hydrazines; Iontophoresis; N-Methylaspartate; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Nitrogen Oxides; Visual Cortex | 1997 |
Cardiovascular effects of nitric oxide and N-methyl-D-aspartate receptors in the nucleus tractus solitarii of rats.
Topics: Animals; Arginine; Blood Pressure; Brain Mapping; Brain Stem; Excitatory Amino Acid Antagonists; Glutamic Acid; Heart Rate; Male; Microinjections; N-Methylaspartate; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Solitary Nucleus | 1997 |
Effects of 2-amino-7-phosphonohepatanoic acid, melatonin or NG-nitro-L-arginine on cyanide or N-methyl-D-aspartate-induced neurotoxicity in rat cortical cells.
Topics: 2-Amino-5-phosphonovalerate; Animals; Arginine; Cells, Cultured; Cerebral Cortex; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Free Radicals; In Vitro Techniques; L-Lactate Dehydrogenase; Melatonin; N-Methylaspartate; Neurons; Nitric Oxide Synthase; Poisons; Potassium Cyanide; Rats | 1998 |
On the intrinsic mechanisms of spontaneous motility in chick embryos.
Topics: Animals; Arginine; Chick Embryo; Movement; N-Methylaspartate; Nitric Oxide; Nitric Oxide Synthase | 1998 |
Effects of moderate, central fluid percussion traumatic brain injury on nitric oxide synthase activity in rats.
Topics: Analysis of Variance; Animals; Arginine; Blood Pressure; Brain Injuries; Cerebral Cortex; Cerebrovascular Circulation; Disease Models, Animal; Excitatory Amino Acid Agonists; Ionomycin; Ionophores; Male; N-Methylaspartate; Nitric Oxide Synthase; Potassium Chloride; Rats; Rats, Sprague-Dawley | 1998 |
The role of nitric oxide in striatal acetylcholine release induced by N-methyl-D-aspartate.
Topics: Acetylcholine; Animals; Arginine; Corpus Striatum; Dibutyryl Cyclic GMP; Dizocilpine Maleate; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Male; N-Methylaspartate; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; omega-N-Methylarginine; Piperazines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate | 1998 |
Arginine availability controls the N-methyl-D-aspartate-induced nitric oxide synthesis: involvement of a glial-neuronal arginine transfer.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Arginine; Cerebellum; Cerebral Cortex; Cyclic GMP; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; In Vitro Techniques; N-Methylaspartate; Neuroglia; Neurons; Nitric Oxide; Nitroarginine; Rats; Rats, Inbred Strains | 1998 |
Nitric oxide facilitates N-methyl-D-aspartate-induced burst firing in dopamine neurons from rat midbrain slices.
Topics: Animals; Apamin; Arginine; Dopamine; Drug Synergism; Electrophysiology; Enzyme Inhibitors; In Vitro Techniques; Indazoles; Male; Mesencephalon; N-Methylaspartate; Neurons; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroarginine; Rats; Rats, Sprague-Dawley | 1998 |
[Nitric oxide in the rat cerebral cortex in seizure models: potential ways of pharmacological modulation].
Topics: Animals; Anticonvulsants; Arginine; Convulsants; Dizocilpine Maleate; Electron Spin Resonance Spectroscopy; Electroshock; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Male; N-Methylaspartate; Nitric Oxide; Nitroarginine; Pentylenetetrazole; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Seizures; Semicarbazides | 1998 |
Intracellular polyamine levels are involved in NMDA-evoked nitric oxide production in chick retina cells.
Topics: Animals; Arginine; Cells, Cultured; Chick Embryo; Citrulline; Cyclic GMP; Eflornithine; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Glycine; N-Methylaspartate; NADPH Dehydrogenase; Nitric Oxide; Nitric Oxide Synthase; Polyamines; Receptors, N-Methyl-D-Aspartate; Retina; Spermidine | 1999 |
Nitric oxide synthase inhibitors enhance 5-HT2 receptor-mediated behavior, the head-twitch response in mice.
Topics: Animals; Arginine; Dextromethorphan; Dizocilpine Maleate; Dose-Response Relationship, Drug; Enzyme Inhibitors; Head Movements; Male; Methylene Blue; Mice; Mice, Inbred ICR; Molsidomine; N-Methylaspartate; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitroprusside; Penicillamine; Receptors, Serotonin; Serotonin; Serotonin Antagonists | 1999 |
Nitric oxide regulation of gonadotrophin secretion in prepubertal heifers1.
Topics: Animals; Arginine; Cattle; Drug Combinations; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Female; Follicle Stimulating Hormone; Gonadotropins; Luteinizing Hormone; N-Methylaspartate; NG-Nitroarginine Methyl Ester; Nitric Oxide | 1999 |
Peripheral nitric oxide contributes to both formalin- and NMDA-induced activation of nociceptors: An immunocytochemical study in rats.
Topics: Animals; Arginine; Enzyme Inhibitors; Formaldehyde; Immunohistochemistry; Male; N-Methylaspartate; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nociceptors; Rats; Rats, Wistar | 1999 |
Inhibition of excitatory neurotransmitter-nitric oxide signaling pathway by inhalational anesthetics.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Anesthetics, Inhalation; Animals; Arginine; Cells, Cultured; Cerebral Cortex; Cyclic GMP; Drug Interactions; Enzyme Activation; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Guanylate Cyclase; Halothane; Isoflurane; Kainic Acid; N-Methylaspartate; Neurons; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitroprusside; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Signal Transduction | 1999 |
Interactions between N-methyl-D-aspartate and nitric oxide in the modulation of ultrasonic vocalizations of infant rats.
Topics: Animals; Animals, Newborn; Arginine; Behavior, Animal; Body Temperature; Drug Interactions; Excitatory Amino Acid Antagonists; Female; Gravity Sensing; Male; Motor Activity; N-Methylaspartate; NG-Nitroarginine Methyl Ester; Nitric Oxide; Piperazines; Rats; Rats, Long-Evans; Ultrasonics; Vocalization, Animal | 2000 |
Nitric oxide limits pressor responses to sympathetic activation in rat spinal cord.
Topics: Anesthesia; Animals; Arginine; Calcium; Enzyme Activation; Enzyme Inhibitors; Male; Molsidomine; N-Methylaspartate; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Pressoreceptors; Rats; Rats, Inbred WKY; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Sympathetic Nervous System | 2000 |
Pituitary hormone and insulin responses to infusion of amino acids and N-methyl-D,L-aspartate in horses.
Topics: Amino Acids; Animals; Arginine; Aspartic Acid; Female; Glutamic Acid; Growth Hormone; Horses; Insulin; Lysine; Male; N-Methylaspartate; Pituitary Hormones; Prolactin; Radioimmunoassay; Thyrotropin | 2001 |
Activity-dependent nitric oxide concentration dynamics in the laterodorsal tegmental nucleus in vitro.
Topics: Animals; Arginine; Calcium; Cholinergic Fibers; Electric Stimulation; Electrochemistry; Excitatory Amino Acid Agonists; Extracellular Space; Female; Guinea Pigs; Hemoglobins; In Vitro Techniques; N-Methylaspartate; Neurons; Nitric Oxide; Nitric Oxide Synthase; Osmolar Concentration; Raphe Nuclei; Signal Transduction; Tegmentum Mesencephali; Tissue Distribution | 2001 |
L-citrulline recycling by argininosuccinate synthetase and lyase in rat gastric fundus.
Topics: Animals; Arginase; Arginine; Argininosuccinate Lyase; Argininosuccinate Synthase; Argininosuccinic Acid; Aspartic Acid; Citrulline; Dinoprost; Electric Stimulation; Enzyme Inhibitors; Gastric Fundus; Glutamic Acid; Glutamine; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth; N-Methylaspartate; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Rats; Rats, Wistar; Thiolester Hydrolases; Ubiquitin Thiolesterase | 2002 |
Behavioral effects of NMDA receptor agonists and antagonists in combination with nitric oxide-related compounds.
Topics: 2-Amino-5-phosphonovalerate; Animals; Arginine; Conditioning, Operant; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Combinations; Drug Interactions; Gallic Acid; Guanidines; Indazoles; Injections, Intraperitoneal; Kynurenic Acid; Molsidomine; N-Methylaspartate; NG-Nitroarginine Methyl Ester; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitroprusside; Phencyclidine; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 2003 |
Role of Arg100 in the active site of adenosylcobalamin-dependent glutamate mutase.
Topics: Arginine; Bacterial Proteins; Binding Sites; Catalysis; Cobamides; Deuterium; Glutamic Acid; Hydrogen Bonding; Intramolecular Transferases; Kinetics; Lysine; Mutagenesis, Site-Directed; N-Methylaspartate; Spectrophotometry; Substrate Specificity; Vitamin B 12 | 2004 |
Release of arginine, glutamate and glutamine in the hippocampus of freely moving rats: Involvement of nitric oxide.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Arginine; Behavior, Animal; Drug Interactions; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Glutamic Acid; Glutamine; Hippocampus; Indazoles; Male; Microdialysis; N-Methylaspartate; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Oxadiazoles; Penicillamine; Quinoxalines; Rats; Rats, Wistar; Wakefulness | 2005 |
Ion permeation through a voltage- sensitive gating pore in brain sodium channels having voltage sensor mutations.
Topics: Amino Acid Substitution; Animals; Arginine; Electric Stimulation; Excitatory Amino Acids; Ion Channel Gating; Ion Channels; Membrane Potentials; Mutagenesis, Site-Directed; Mutation; N-Methylaspartate; NAV1.2 Voltage-Gated Sodium Channel; Nerve Tissue Proteins; Neural Conduction; Oocytes; Patch-Clamp Techniques; Potassium Channel Blockers; Sodium Channel Blockers; Sodium Channels; Tetraethylammonium; Tetrodotoxin; Transfection; Xenopus | 2005 |
Defensive-like behaviors and antinociception induced by NMDA injection into the periaqueductal gray of mice depend on nitric oxide synthesis.
Topics: Analysis of Variance; Animals; Arginine; Behavior, Animal; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Freezing Reaction, Cataleptic; Male; Mice; N-Methylaspartate; Nitric Oxide Synthase; Pain; Pain Measurement; Periaqueductal Gray; Reaction Time; Running | 2006 |
Inhibition of protein synthesis by activation of NMDA receptors in cultured retinal cells: a new mechanism for the regulation of nitric oxide production.
Topics: Animals; Arginine; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Chick Embryo; Citrulline; Elongation Factor 2 Kinase; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; N-Methylaspartate; Nerve Tissue Proteins; Neuroglia; Neurons; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Peptide Elongation Factor 2; Phosphorylation; Protein Synthesis Inhibitors; Receptors, N-Methyl-D-Aspartate; Retina; Up-Regulation | 2006 |
Cortical feedback to the thalamus is selectively enhanced by nitric oxide.
Topics: Animals; Animals, Newborn; Arginine; Cerebral Cortex; Cyclic GMP; Drug Interactions; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Feedback; Ferrets; Geniculate Bodies; In Vitro Techniques; Male; N-Methylaspartate; Neural Pathways; Neurons; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Penicillamine; Superoxide Dismutase; Synaptic Transmission; Triazoles | 2006 |
Role of the L-citrulline/L-arginine cycle in iNANC nerve-mediated nitric oxide production and airway smooth muscle relaxation in allergic asthma.
Topics: Allergens; Animals; Arginine; Argininosuccinate Lyase; Argininosuccinate Synthase; Asthma; Citrulline; Disease Models, Animal; Electric Stimulation; Enzyme Inhibitors; Guinea Pigs; Male; Muscle Relaxation; Muscle, Smooth; N-Methylaspartate; Neural Inhibition; Neurons; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type I; Ovalbumin; Specific Pathogen-Free Organisms; Succinic Acid; Trachea | 2006 |
Effects of N-methyl-D-aspartate on extracellular citrulline level in the rat nucleus accumbens.
Topics: Animals; Arginine; Citrulline; Dizocilpine Maleate; Dose-Response Relationship, Drug; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Extracellular Space; Male; Microdialysis; N-Methylaspartate; Nucleus Accumbens; Rats; Rats, Sprague-Dawley | 2006 |
CaMKII translocation requires local NMDA receptor-mediated Ca2+ signaling.
Topics: Animals; Arginine; Calcium Signaling; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Dendritic Spines; Mice; Models, Neurological; Mutant Proteins; N-Methylaspartate; Protein Transport; Receptors, N-Methyl-D-Aspartate; Synapses | 2006 |
Antidepressant-like effect of folic acid: Involvement of NMDA receptors and L-arginine-nitric oxide-cyclic guanosine monophosphate pathway.
Topics: Animals; Antidepressive Agents; Arginine; Cyclic GMP; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Female; Folic Acid; Indazoles; Injections, Intraventricular; Male; Methylene Blue; Mice; N-Methylaspartate; Nitric Oxide; Nitric Oxide Donors; Receptors, N-Methyl-D-Aspartate; S-Nitroso-N-Acetylpenicillamine; Signal Transduction; Swimming; Vitamin B Complex | 2008 |
Role of glutamate NMDA receptors and nitric oxide located within the periaqueductal gray on defensive behaviors in mice confronted by predator.
Topics: Animals; Arginine; Avoidance Learning; Behavior, Animal; Dose-Response Relationship, Drug; Fear; Freezing Reaction, Cataleptic; Male; Mice; N-Methylaspartate; Nitric Oxide; Nitric Oxide Synthase Type I; Periaqueductal Gray; Predatory Behavior; Rats; Rats, Long-Evans; Receptors, N-Methyl-D-Aspartate | 2009 |
Argininosuccinate synthetase is a functional target for a snake venom anti-hypertensive peptide: role in arginine and nitric oxide production.
Topics: Animals; Antihypertensive Agents; Arginine; Argininosuccinate Synthase; Blood Pressure; Bothrops; Cells, Cultured; Crotalid Venoms; Endothelial Cells; Guinea Pigs; Humans; Kidney; Male; Mice; Mice, Inbred BALB C; N-Methylaspartate; Nitrogen Oxides; Protein Binding; Rats; Rats, Inbred SHR; Rats, Wistar | 2009 |
Modulation of GABA release by nitric oxide in the chick retina: different effects of nitric oxide depending on the cell population.
Topics: Amacrine Cells; Animals; Arginine; Chickens; gamma-Aminobutyric Acid; N-Methylaspartate; Nitric Oxide; Nitric Oxide Synthase Type I; Retina; Retinal Ganglion Cells; Tissue Culture Techniques; Tissue Fixation | 2009 |
Immunoneutralization of agmatine sensitizes mice to micro-opioid receptor tolerance.
Topics: Agmatine; Analgesics, Opioid; Animals; Antibodies, Blocking; Arginine; Behavior, Animal; Dose-Response Relationship, Drug; Drug Tolerance; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Excitatory Amino Acid Agonists; Guinea Pigs; Immunoglobulin G; Immunohistochemistry; Injections, Spinal; Male; Mice; N-Methylaspartate; Oligopeptides; Pain Measurement; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Spinal Cord | 2009 |
Metabotropic glutamate receptor 5, but not 1, modulates NMDA receptor-mediated activation of neuronal nitric oxide synthase.
Topics: Animals; Arginine; Blotting, Western; Calcium; Cells, Cultured; Cerebellum; Citrulline; Cyclic AMP; Cyclic GMP; Enzyme Activation; Excitatory Amino Acid Agonists; Guanylate Cyclase; N-Methylaspartate; Neurons; Nitrates; Nitric Oxide Synthase Type I; Nitrites; Oncogene Protein v-akt; Rats; Rats, Wistar; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate | 2010 |
Phenotypic characterization of a new Grin1 mutant mouse generated by ENU mutagenesis.
Topics: Alkylating Agents; Amino Acid Sequence; Analysis of Variance; Animals; Arginine; Calcium; Carrier Proteins; Cells, Cultured; Central Nervous System Stimulants; Cerebral Cortex; Chromosome Mapping; Cysteine; Embryo, Mammalian; Ethylnitrosourea; Exploratory Behavior; Gene Expression Regulation; Male; Methylphenidate; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Transgenic; Mitogen-Activated Protein Kinase 1; Motor Activity; Mutagenesis; Mutation, Missense; N-Methylaspartate; Nerve Tissue Proteins; Neurons; Phenazines; Phenotype; Proto-Oncogene Proteins c-fos; Receptors, N-Methyl-D-Aspartate | 2010 |
[NMDA-dependent increase of exracellular arginine level in the nucleus accumbens is mediated by NO-synthase activation].
Topics: Animals; Arginine; Brain Chemistry; Chromatography, High Pressure Liquid; Dizocilpine Maleate; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Male; Microdialysis; N-Methylaspartate; Nitric Oxide Synthase; Nitroarginine; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 2010 |
Chronic intermittent hypoxia induces NMDA receptor-dependent plasticity and suppresses nitric oxide signaling in the mouse hypothalamic paraventricular nucleus.
Topics: Analysis of Variance; Animals; Arginine; Blood Gas Analysis; Blood Pressure; Cyclic N-Oxides; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Free Radical Scavengers; Hydrogen-Ion Concentration; Hypoxia; Imidazoles; In Vitro Techniques; Male; Membrane Potentials; Mice; Mice, Inbred C57BL; Microscopy, Electron, Transmission; N-Methylaspartate; Neuronal Plasticity; Neurons; Nitric Oxide; Nitric Oxide Synthase Type I; Paraventricular Hypothalamic Nucleus; Receptors, N-Methyl-D-Aspartate; S-Nitroso-N-Acetylpenicillamine; Signal Transduction; Time Factors; Vasopressins | 2010 |
Blockade of NMDA or NO in the dorsal premammillary nucleus attenuates defensive behaviors.
Topics: 2-Amino-5-phosphonovalerate; Animals; Arginine; Behavior, Animal; Cats; Defense Mechanisms; Excitatory Amino Acid Antagonists; Fear; Freezing Reaction, Cataleptic; Locomotion; Male; Mammillary Bodies; N-Methylaspartate; Nitric Oxide; Rats; Rats, Wistar; Statistics, Nonparametric | 2011 |
Homeostatic NMDA receptor down-regulation via brain derived neurotrophic factor and nitric oxide-dependent signalling in cortical but not in hippocampal neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Analysis of Variance; Animals; Animals, Newborn; Arginine; Bicuculline; Brain-Derived Neurotrophic Factor; Calcium; Cells, Cultured; Cerebral Cortex; Down-Regulation; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; GABA-A Receptor Antagonists; Guanylate Cyclase; Hippocampus; Intracellular Fluid; Larva; Male; N-Methylaspartate; Neurons; Nitric Oxide; Post-Synaptic Density; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Synaptosomes; Xenopus | 2011 |
Involvement of nitric oxide-cGMP pathway in the antidepressant-like effect of ascorbic acid in the tail suspension test.
Topics: Animals; Antidepressive Agents; Arginine; Ascorbic Acid; Cyclic GMP; Depression; Disease Models, Animal; Dizocilpine Maleate; Enzyme Inhibitors; Exploratory Behavior; Female; Hindlimb Suspension; Indazoles; Mice; N-Methylaspartate; Nitric Oxide; Oxadiazoles; Piperazines; Purines; Quinoxalines; Signal Transduction; Sildenafil Citrate; Sulfones | 2011 |
Guanosine produces an antidepressant-like effect through the modulation of NMDA receptors, nitric oxide-cGMP and PI3K/mTOR pathways.
Topics: Analysis of Variance; Animals; Antidepressive Agents; Arginine; Cyclic GMP; Depression; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Excitatory Amino Acid Agents; Exploratory Behavior; Female; Freezing Reaction, Cataleptic; Guanosine; Hindlimb Suspension; Immunosuppressive Agents; Male; Mice; N-Methylaspartate; Nitric Oxide; Phosphatidylinositol 3-Kinases; Receptors, N-Methyl-D-Aspartate; Serine; Signal Transduction; Sirolimus; Swimming; TOR Serine-Threonine Kinases | 2012 |
Depletion of arginine by recombinant arginine deiminase induces nNOS-activated neurotoxicity in neuroblastoma cells.
Topics: Arginine; Cell Culture Techniques; Cell Survival; Humans; Hydrolases; Membrane Potential, Mitochondrial; N-Methylaspartate; Neurodegenerative Diseases; Neurons; Nitric Oxide; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Recombinant Proteins | 2014 |
Antidepressant-like effect of quercetin in bulbectomized mice and involvement of the antioxidant defenses, and the glutamatergic and oxidonitrergic pathways.
Topics: Animals; Antidepressive Agents; Antioxidants; Arginine; Behavior, Animal; Disease Models, Animal; Drug Synergism; Fluoxetine; Hippocampus; Indazoles; Male; Methylene Blue; Mice; N-Methylaspartate; Olfactory Bulb; Oxidative Stress; Quercetin; Signal Transduction; Sildenafil Citrate | 2015 |
Contribution of NMDA, GABAA and GABAB receptors and l-arginine-NO-cGMP, MEK1/2 and CaMK-II pathways in the antidepressant-like effect of 7-fluoro-1,3-diphenylisoquinoline-1-amine in mice.
Topics: Animals; Antidepressive Agents; Arginine; Biological Transport; Cyclic GMP; Glutamic Acid; Locomotion; Male; MAP Kinase Kinase 1; MAP Kinase Kinase 2; Mice; N-Methylaspartate; Nitric Oxide; Quinolines; Receptors, GABA-A; Receptors, GABA-B; Receptors, N-Methyl-D-Aspartate; Signal Transduction | 2016 |
Antidepressant effect of pramipexole in mice forced swimming test: A cross talk between dopamine receptor and NMDA/nitric oxide/cGMP pathway.
Topics: Animals; Antidepressive Agents; Arginine; Benzothiazoles; Cyclic GMP; Dizocilpine Maleate; Haloperidol; Immobilization; Injections, Intraperitoneal; Male; Methylene Blue; Mice; Motor Activity; N-Methylaspartate; NG-Nitroarginine Methyl Ester; Nitric Oxide; Pramipexole; Receptors, Dopamine; Signal Transduction; Sildenafil Citrate; Swimming | 2016 |
Pharmacological evidence for the involvement of the NMDA receptor and nitric oxide pathway in the antidepressant-like effect of lamotrigine in the mouse forced swimming test.
Topics: Animals; Antidepressive Agents; Arginine; Dizocilpine Maleate; Immobilization; Lamotrigine; Male; Methylene Blue; Mice; Motor Activity; N-Methylaspartate; NG-Nitroarginine Methyl Ester; Nitric Oxide; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Sildenafil Citrate; Swimming; Time Factors; Triazines | 2016 |
The Neuronal Ischemic Tolerance Is Conditioned by the Tp53 Arg72Pro Polymorphism.
Topics: Aged; Aged, 80 and over; Animals; Apoptosis; Arginine; Brain Ischemia; Caspase 3; Cell Hypoxia; Cells, Cultured; Cerebral Cortex; Cohort Studies; Electron Transport Complex IV; Embryo, Mammalian; Excitatory Amino Acid Agonists; Female; Glucose; Humans; Ischemic Preconditioning; Male; Membrane Potentials; Mice; Microtubule-Associated Proteins; Middle Aged; N-Methylaspartate; Neurons; Polymorphism, Single Nucleotide; Proline; Subcellular Fractions; Tumor Suppressor Protein p53 | 2019 |
NMDA-induced nitric oxide generation and CREB activation in central nervous system is dependent on eukaryotic elongation factor 2 kinase.
Topics: Animals; Arginine; Central Nervous System; Chickens; Cyclic AMP Response Element-Binding Protein; Cycloheximide; Elongation Factor 2 Kinase; Indazoles; Male; N-Methylaspartate; Nitric Oxide; Phosphorylation; Pyridines; Pyrimidines; Rats | 2020 |
Valproic acid up-regulates the whole NO-citrulline cycle for potent iNOS-NO signaling to promote neuronal differentiation of adipose tissue-derived stem cells.
Topics: Adipose Tissue; Animals; Arginine; Argininosuccinate Synthase; Cell Differentiation; Citrulline; Enzyme Inhibitors; Male; N-Methylaspartate; Neurons; Nitric Oxide; Nitric Oxide Synthase Type II; Rats, Wistar; Signal Transduction; Stem Cells; Up-Regulation; Valproic Acid | 2021 |
Antidepressant-like effect of ethanol in mice forced swimming test is mediated via inhibition of NMDA/nitric oxide/cGMP signaling pathway.
Topics: Animals; Antidepressive Agents; Arginine; Cyclic GMP; Depression; Ethanol; Mice; N-Methylaspartate; Nitric Oxide; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Swimming | 2021 |
Mechanistic pathways of fibromyalgia induced by intermittent cold stress in mice is sex-dependently.
Topics: Adenosine Triphosphatases; Animals; Arginine; Cold-Shock Response; Cyclic GMP; Dizocilpine Maleate; Female; Fibromyalgia; Male; Methylene Blue; Mice; N-Methylaspartate; Nitric Oxide; Quality of Life; Receptors, N-Methyl-D-Aspartate | 2022 |